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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for figla

Z-value: 0.92

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Transcription factors associated with figla

Gene Symbol Gene ID Gene Info
figla
ENSDARG00000087166 folliculogenesis specific bHLH transcription factor
figla
ENSDARG00000115572 folliculogenesis specific bHLH transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
figladr11_v1_chr5_-_13848296_138482960.465.4e-02Click!

Activity profile of figla motif

Sorted Z-values of figla motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_58751504 3.27 ENSDART00000024185
zgc:56231
zgc:56231
chr5_-_23696926 2.58 ENSDART00000021462
rnf128a
ring finger protein 128a
chr15_+_38299385 2.56 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr10_-_25217347 2.42 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr15_+_38299563 2.40 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr7_+_57089354 2.28 ENSDART00000140702
scamp2l
secretory carrier membrane protein 2, like
chr10_-_31805923 2.11 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr5_+_57924611 2.11 ENSDART00000050949
btg4
B-cell translocation gene 4
chr13_-_21672131 1.96 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr5_-_15494164 1.90 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
taok3a
TAO kinase 3a
chr2_-_50225411 1.89 ENSDART00000147117
ENSDART00000000042
mcm6l
MCM6 minichromosome maintenance deficient 6, like
chr2_-_17114852 1.88 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr24_-_2423791 1.82 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr19_+_32979331 1.79 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr7_+_57088920 1.68 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr2_-_17115256 1.67 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr7_+_67699178 1.65 ENSDART00000160086
zgc:162592
zgc:162592
chr4_-_858434 1.61 ENSDART00000006961
sobpb
sine oculis binding protein homolog (Drosophila) b
chr14_+_24840669 1.46 ENSDART00000106039
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr6_-_37749711 1.42 ENSDART00000078324
nipa1
non imprinted in Prader-Willi/Angelman syndrome 1
chr5_-_29531948 1.37 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr8_+_45334255 1.36 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr5_+_28271412 1.35 ENSDART00000031727
vamp8
vesicle-associated membrane protein 8 (endobrevin)
chr20_-_21672970 1.34 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr1_-_6085750 1.31 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr22_+_11756040 1.29 ENSDART00000105808
krt97
keratin 97
chr4_-_12978925 1.26 ENSDART00000013839
tmbim4
transmembrane BAX inhibitor motif containing 4
chr6_-_49537646 1.25 ENSDART00000180438
FO704848.1

chr7_+_67699009 1.24 ENSDART00000192810
zgc:162592
zgc:162592
chr18_+_45666489 1.23 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr5_-_22052852 1.23 ENSDART00000002938
mtmr8
myotubularin related protein 8
chr11_-_6452444 1.22 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr21_-_21178410 1.22 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
ftsj1
FtsJ RNA methyltransferase homolog 1
chr11_+_13423776 1.22 ENSDART00000102553
homer3b
homer scaffolding protein 3b
chr24_-_34335265 1.20 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr13_+_39282477 1.19 ENSDART00000132198
si:dkey-85a20.4
si:dkey-85a20.4
chr3_+_26245731 1.18 ENSDART00000103734
atad5a
ATPase family, AAA domain containing 5a
chr10_+_37173029 1.17 ENSDART00000136510
ksr1a
kinase suppressor of ras 1a
chr14_+_35464994 1.17 ENSDART00000115307
si:ch211-203d1.3
si:ch211-203d1.3
chr18_+_45573416 1.16 ENSDART00000132184
ENSDART00000145288
kifc3
kinesin family member C3
chr10_-_2942900 1.16 ENSDART00000002622
oclna
occludin a
chr19_+_43684376 1.14 ENSDART00000051723
si:ch211-193k19.1
si:ch211-193k19.1
chr23_-_31810222 1.14 ENSDART00000134319
ENSDART00000139076
hbs1l
HBS1-like translational GTPase
chr22_-_17677947 1.14 ENSDART00000139911
tjp3
tight junction protein 3
chr23_+_9522942 1.12 ENSDART00000137751
osbpl2b
oxysterol binding protein-like 2b
chr18_+_45573251 1.09 ENSDART00000191309
kifc3
kinesin family member C3
chr6_-_8360918 1.08 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr4_-_13614797 1.07 ENSDART00000138366
ENSDART00000165212
irf5
interferon regulatory factor 5
chr2_+_1988036 1.07 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr5_-_65121747 1.05 ENSDART00000165556
tor2a
torsin family 2, member A
chr2_-_57916317 1.05 ENSDART00000183930
si:dkeyp-68b7.7
si:dkeyp-68b7.7
chr3_+_19665319 1.05 ENSDART00000007857
ENSDART00000193509
mettl2a
methyltransferase like 2A
chr20_-_13625588 1.04 ENSDART00000078893
sytl3
synaptotagmin-like 3
chr14_-_31087830 1.03 ENSDART00000002250
hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr16_-_20932896 1.03 ENSDART00000180646
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr21_-_4250682 1.02 ENSDART00000099389
dnlz
DNL-type zinc finger
chr2_+_43204919 1.01 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
pard3ab
par-3 family cell polarity regulator alpha, b
chr2_+_37838259 1.01 ENSDART00000136796
parp2
poly (ADP-ribose) polymerase 2
chr23_+_9522781 1.01 ENSDART00000136486
osbpl2b
oxysterol binding protein-like 2b
chr3_+_42923275 1.00 ENSDART00000168228
tmem184a
transmembrane protein 184a
chr21_+_17016337 1.00 ENSDART00000065755
gpn3
GPN-loop GTPase 3
chr19_+_7636941 1.00 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr1_+_594584 0.99 ENSDART00000135944
jam2a
junctional adhesion molecule 2a
chr3_-_26183699 0.99 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr12_-_23365737 0.98 ENSDART00000170376
mpp7a
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr1_+_20593653 0.97 ENSDART00000132440
si:ch211-142c4.1
si:ch211-142c4.1
chr5_-_25572151 0.97 ENSDART00000144995
si:dkey-229d2.4
si:dkey-229d2.4
chr1_+_45958904 0.96 ENSDART00000108528
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b
chr3_-_29962345 0.95 ENSDART00000136819
bcat2
branched chain amino-acid transaminase 2, mitochondrial
chr7_-_48251234 0.94 ENSDART00000024062
ENSDART00000098904
cpeb1b
cytoplasmic polyadenylation element binding protein 1b
chr19_-_10214264 0.93 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr5_-_29152457 0.92 ENSDART00000078469
noxa1
NADPH oxidase activator 1
chr14_-_35672890 0.91 ENSDART00000074710
pdgfc
platelet derived growth factor c
chr3_-_2613990 0.91 ENSDART00000137102
si:dkey-217f16.6
si:dkey-217f16.6
chr12_-_4301234 0.90 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr12_-_47601845 0.90 ENSDART00000169548
ENSDART00000182889
rgs7b
regulator of G protein signaling 7b
chr5_+_6670945 0.89 ENSDART00000185686
pxna
paxillin a
chr9_-_28939181 0.89 ENSDART00000101276
ENSDART00000135334
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr5_-_69212184 0.88 ENSDART00000053963
mat2ab
methionine adenosyltransferase II, alpha b
chr11_+_34921492 0.86 ENSDART00000128070
gnai2a
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr5_+_4016271 0.85 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
ggnbp2
gametogenetin binding protein 2
chr1_-_53625142 0.84 ENSDART00000166852
USP34
ubiquitin specific peptidase 34
chr19_-_30404096 0.83 ENSDART00000103475
agr2
anterior gradient 2
chr14_+_591216 0.83 ENSDART00000169624
zgc:158257
zgc:158257
chr17_+_1360192 0.82 ENSDART00000184561
siva1
SIVA1, apoptosis-inducing factor
chr13_+_31716820 0.82 ENSDART00000034745
prkcha
protein kinase C, eta, a
chr11_-_43473824 0.82 ENSDART00000179561
tmem63bb
transmembrane protein 63Bb
chr18_+_22220656 0.81 ENSDART00000191862
ripor1
RHO family interacting cell polarization regulator 1
chr20_-_1191910 0.81 ENSDART00000043218
ube2j1
ubiquitin-conjugating enzyme E2, J1
chr22_-_5171829 0.80 ENSDART00000140313
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr14_-_33277743 0.80 ENSDART00000048130
stard14
START domain containing 14
chr16_+_43077909 0.79 ENSDART00000014140
rundc3b
RUN domain containing 3b
chr6_-_41135215 0.79 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr21_+_39100289 0.79 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr5_+_54497730 0.78 ENSDART00000157722
tmem203
transmembrane protein 203
chr14_-_33278084 0.78 ENSDART00000132850
stard14
START domain containing 14
chr2_+_27855102 0.78 ENSDART00000150330
buc
bucky ball
chr5_+_54497475 0.78 ENSDART00000158149
ENSDART00000163968
ENSDART00000160446
tmem203
transmembrane protein 203
chr2_+_9560740 0.77 ENSDART00000003465
gipc2
GIPC PDZ domain containing family, member 2
chr15_+_34963316 0.76 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr4_-_277081 0.76 ENSDART00000166174
si:ch73-252i11.1
si:ch73-252i11.1
chr15_-_29326254 0.76 ENSDART00000114492
si:dkey-52l18.4
si:dkey-52l18.4
chr11_-_44999858 0.76 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr6_+_42338309 0.75 ENSDART00000015277
gpx1b
glutathione peroxidase 1b
chr23_-_18057851 0.75 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr6_-_13709591 0.74 ENSDART00000151771
chpfb
chondroitin polymerizing factor b
chr16_-_47381519 0.74 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
si:dkey-256h2.1
chr15_-_5624361 0.73 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr21_-_17016788 0.72 ENSDART00000186703
AL844518.1

chr11_+_18873619 0.71 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr1_-_20593778 0.71 ENSDART00000124770
ugt8
UDP glycosyltransferase 8
chr6_-_12912606 0.71 ENSDART00000164640
ical1
islet cell autoantigen 1-like
chr23_-_19831739 0.70 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr2_+_27855346 0.70 ENSDART00000175159
ENSDART00000192645
buc
bucky ball
chr7_+_67748939 0.69 ENSDART00000162978
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr14_-_16810401 0.68 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr4_+_13901458 0.68 ENSDART00000137549
pphln1
periphilin 1
chr23_+_4741543 0.68 ENSDART00000144761
raf1a
Raf-1 proto-oncogene, serine/threonine kinase a
chr7_+_17096281 0.68 ENSDART00000035558
htatip2
HIV-1 Tat interactive protein 2
chr18_+_13248956 0.67 ENSDART00000080709
plcg2
phospholipase C, gamma 2
chr5_+_62374092 0.67 ENSDART00000082965
CU928117.1

chr14_-_45551572 0.67 ENSDART00000111410
ganab
glucosidase, alpha; neutral AB
chr8_-_14554785 0.67 ENSDART00000057645
qsox1
quiescin Q6 sulfhydryl oxidase 1
chr5_+_58679071 0.66 ENSDART00000019561
zgc:171734
zgc:171734
chr8_-_13735572 0.66 ENSDART00000139642
si:dkey-258f14.7
si:dkey-258f14.7
chr13_+_8892784 0.66 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr11_+_24313931 0.65 ENSDART00000017599
ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr23_-_25686894 0.65 ENSDART00000181420
ENSDART00000088208
lrp1ab
low density lipoprotein receptor-related protein 1Ab
chr12_-_3773869 0.65 ENSDART00000092983
si:ch211-166g5.4
si:ch211-166g5.4
chr22_+_30046365 0.65 ENSDART00000192546
add3a
adducin 3 (gamma) a
chr8_-_11324143 0.64 ENSDART00000008215
pip5k1bb
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr10_-_26218354 0.64 ENSDART00000180764
arfip2b
ADP-ribosylation factor interacting protein 2b
chr3_-_58165254 0.64 ENSDART00000093031
snu13a
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr23_-_18130264 0.63 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr23_-_18057553 0.63 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr15_+_29024895 0.63 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr17_+_132555 0.62 ENSDART00000158159
zgc:77287
zgc:77287
chr2_+_21048661 0.62 ENSDART00000156876
rreb1b
ras responsive element binding protein 1b
chr16_+_19637384 0.61 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr11_-_26701611 0.61 ENSDART00000083010
acad9
acyl-CoA dehydrogenase family, member 9
chr20_-_40367493 0.60 ENSDART00000075096
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr17_+_23462972 0.59 ENSDART00000112959
ENSDART00000192168
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr12_+_33484458 0.59 ENSDART00000000069
slc9a3r1a
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr2_+_34967022 0.58 ENSDART00000134926
astn1
astrotactin 1
chr4_-_21466480 0.58 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr21_+_30673183 0.57 ENSDART00000144652
clcn5a
chloride channel, voltage-sensitive 5a
chr1_+_59328030 0.57 ENSDART00000172464
CABZ01052576.1

chr1_+_594736 0.57 ENSDART00000166731
jam2a
junctional adhesion molecule 2a
chr5_-_64431927 0.56 ENSDART00000158248
brd3b
bromodomain containing 3b
chr14_-_47963115 0.56 ENSDART00000003826
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr6_-_55423220 0.55 ENSDART00000158929
ctsa
cathepsin A
chr15_-_23485752 0.55 ENSDART00000152706
nlrx1
NLR family member X1
chr21_-_34261677 0.54 ENSDART00000124649
ENSDART00000172381
ENSDART00000064320
alg13
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr8_-_15211164 0.53 ENSDART00000110550
bcar3
BCAR3, NSP family adaptor protein
chr2_-_27855576 0.52 ENSDART00000121623
FO834800.1

chr2_+_23048620 0.52 ENSDART00000170669
csnk1g2a
casein kinase 1, gamma 2a
chr2_-_39086540 0.52 ENSDART00000110826
NMNAT3
si:ch73-170l17.1
chr9_-_16140860 0.51 ENSDART00000142974
myo1b
myosin IB
chr20_-_28404362 0.51 ENSDART00000055932
ENSDART00000188161
pigh
phosphatidylinositol glycan anchor biosynthesis, class H
chr20_-_874807 0.51 ENSDART00000020506
snx14
sorting nexin 14
chr5_+_31959954 0.51 ENSDART00000142826
myo1hb
myosin IHb
chr3_+_53240562 0.50 ENSDART00000031234
stxbp2
syntaxin binding protein 2
chr20_+_21391181 0.50 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jag2b
jagged 2b
chr22_-_18546649 0.50 ENSDART00000171277
cirbpb
cold inducible RNA binding protein b
chr2_+_34967210 0.49 ENSDART00000141796
astn1
astrotactin 1
chr9_-_29578037 0.49 ENSDART00000189026
cenpj
centromere protein J
chr8_+_44677569 0.48 ENSDART00000191104
grk5l
G protein-coupled receptor kinase 5 like
chr15_-_34878388 0.48 ENSDART00000154094
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr6_-_10728921 0.48 ENSDART00000151484
sp3b
Sp3b transcription factor
chr24_+_33802528 0.47 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
atg9b
autophagy related 9B
chr10_-_1961930 0.47 ENSDART00000122446
tdgf1
teratocarcinoma-derived growth factor 1
chr14_-_32631013 0.47 ENSDART00000176815
atp11c
ATPase phospholipid transporting 11C
chr16_-_42066523 0.47 ENSDART00000180538
ENSDART00000058620
zp3d.1
zona pellucida glycoprotein 3d tandem duplicate 1
chr16_+_26601364 0.47 ENSDART00000087537
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr17_+_15983247 0.47 ENSDART00000154275
clmn
calmin
chr10_-_14929630 0.47 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
smad2
SMAD family member 2
chr20_-_2298970 0.46 ENSDART00000136067
EPB41L2
si:ch73-18b11.1
chr18_+_9493720 0.46 ENSDART00000053125
sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_-_37280617 0.46 ENSDART00000190458
nadkb
NAD kinase b
chr17_-_11151655 0.46 ENSDART00000156383
CU179699.1

chr23_-_31810391 0.46 ENSDART00000189749
ENSDART00000180850
hbs1l
HBS1-like translational GTPase
chr6_-_28961660 0.45 ENSDART00000147285
tomm70a
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr3_-_21061931 0.45 ENSDART00000036741
fam57ba
family with sequence similarity 57, member Ba
chr2_+_21000334 0.45 ENSDART00000062563
ENSDART00000147809
rreb1b
ras responsive element binding protein 1b
chr25_-_893464 0.45 ENSDART00000159321
znf609a
zinc finger protein 609a
chr2_+_37480669 0.44 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr17_-_8692722 0.44 ENSDART00000148931
ENSDART00000192891
ctbp2a
C-terminal binding protein 2a
chr7_+_38962459 0.44 ENSDART00000173851
dgkza
diacylglycerol kinase, zeta a
chr5_-_69923241 0.43 ENSDART00000187389
fktn
fukutin
chr6_-_35032792 0.43 ENSDART00000168256
ddr2a
discoidin domain receptor tyrosine kinase 2a
chr7_+_52887701 0.42 ENSDART00000109973
tp53bp1
tumor protein p53 binding protein, 1
chr8_+_54135642 0.42 ENSDART00000170712
brpf1
bromodomain and PHD finger containing, 1
chr21_-_25722834 0.41 ENSDART00000101208
abhd11
abhydrolase domain containing 11
chr11_+_31730680 0.41 ENSDART00000145497
diaph3
diaphanous-related formin 3
chr23_-_42883522 0.39 ENSDART00000148500
dlgap4a
discs, large (Drosophila) homolog-associated protein 4a
chr21_-_25522906 0.39 ENSDART00000110923
cnksr2b
connector enhancer of kinase suppressor of Ras 2b
chr1_-_50293946 0.39 ENSDART00000053028
ENSDART00000125099
tbck
TBC1 domain containing kinase
chr10_-_1961576 0.38 ENSDART00000042441
tdgf1
teratocarcinoma-derived growth factor 1
chr24_-_35707552 0.38 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr5_+_20030414 0.38 ENSDART00000181430
ENSDART00000047841
ENSDART00000182813
sgsm1a
small G protein signaling modulator 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of figla

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 3.5 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.3 0.9 GO:0090008 hypoblast development(GO:0090008)
0.3 1.4 GO:0070254 mucus secretion(GO:0070254)
0.3 1.0 GO:1902414 protein localization to cell junction(GO:1902414)
0.2 1.5 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.2 0.9 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 1.8 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 2.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.9 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.2 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 1.9 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.7 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 0.6 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.8 GO:0010269 response to selenium ion(GO:0010269)
0.1 1.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.9 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.9 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 1.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 1.1 GO:0045453 bone resorption(GO:0045453)
0.1 0.3 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 2.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.9 GO:0030104 water homeostasis(GO:0030104)
0.1 0.3 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.3 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 3.1 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.4 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.4 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 2.8 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.4 GO:0032979 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1 1.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.5 GO:0061511 centriole elongation(GO:0061511)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.4 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.3 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.3 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.1 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.9 GO:0061055 myotome development(GO:0061055)
0.1 0.9 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 1.0 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.2 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.5 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.6 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.5 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.7 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 1.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 1.0 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.6 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.3 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 2.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 1.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.4 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 1.3 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.4 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.5 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.3 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.9 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.9 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.1 GO:0051607 defense response to virus(GO:0051607)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.6 GO:0021591 ventricular system development(GO:0021591)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.3 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.4 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.1 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.7 GO:0007098 centrosome cycle(GO:0007098)
0.0 3.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.8 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.7 GO:0051170 nuclear import(GO:0051170)
0.0 1.0 GO:0008033 tRNA processing(GO:0008033)
0.0 1.1 GO:0008285 negative regulation of cell proliferation(GO:0008285)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 0.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.1 GO:0030904 retromer complex(GO:0030904)
0.2 1.5 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 2.1 GO:0042555 MCM complex(GO:0042555)
0.1 0.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 2.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 0.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.1 3.5 GO:0005657 replication fork(GO:0005657)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 5.7 GO:0043296 apical junction complex(GO:0043296)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.9 GO:0005871 kinesin complex(GO:0005871)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 3.0 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.6 GO:0099572 postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.4 1.9 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.4 2.9 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.4 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 1.0 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.2 1.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 0.9 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.7 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.9 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 0.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.0 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 2.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.5 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.9 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 2.0 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 2.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.0 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 2.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 1.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0005536 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.2 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 2.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 4.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.6 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.5 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965) GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.8 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.9 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.9 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 2.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 2.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes