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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for fli1b

Z-value: 1.92

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Transcription factors associated with fli1b

Gene Symbol Gene ID Gene Info
fli1b
ENSDARG00000040080 Fli-1 proto-oncogene, ETS transcription factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fli1bdr11_v1_chr16_+_42018041_42018042-0.608.4e-03Click!

Activity profile of fli1b motif

Sorted Z-values of fli1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_30117798 5.57 ENSDART00000135723
ENSDART00000000198
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr20_+_23947004 5.33 ENSDART00000144195
casp8ap2
caspase 8 associated protein 2
chr21_-_4793686 4.49 ENSDART00000158232
notch1a
notch 1a
chr16_-_34195002 4.38 ENSDART00000054026
rcc1
regulator of chromosome condensation 1
chr19_+_10661520 4.12 ENSDART00000091813
ENSDART00000165653
ago3b
argonaute RISC catalytic component 3b
chr23_-_10175898 4.07 ENSDART00000146185
krt5
keratin 5
chr6_-_49547680 4.03 ENSDART00000169678
ppp4r1l
protein phosphatase 4, regulatory subunit 1-like
chr18_+_15271993 3.98 ENSDART00000099777
si:dkey-103i16.6
si:dkey-103i16.6
chr3_+_43102010 3.94 ENSDART00000162096
micall2a
mical-like 2a
chr24_-_2423791 3.81 ENSDART00000190402
rreb1a
ras responsive element binding protein 1a
chr5_-_29512538 3.74 ENSDART00000098364
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr25_-_21782435 3.72 ENSDART00000089616
bmt2
base methyltransferase of 25S rRNA 2 homolog
chr17_-_7733037 3.70 ENSDART00000064657
stx11a
syntaxin 11a
chr9_+_2041535 3.64 ENSDART00000093187
lnpa
limb and neural patterns a
chr23_+_30730121 3.60 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr20_+_27087539 3.49 ENSDART00000062094
tmem251
transmembrane protein 251
chr20_+_27749133 3.43 ENSDART00000089013
vrtn
vertebrae development associated
chr10_-_15849027 3.21 ENSDART00000184682
tjp2a
tight junction protein 2a (zona occludens 2)
chr25_-_25575717 3.17 ENSDART00000067138
hic1l
hypermethylated in cancer 1 like
chr14_-_34605607 3.14 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr6_-_21726758 3.11 ENSDART00000083085
mtmr14
myotubularin related protein 14
chr7_+_41812817 3.10 ENSDART00000174165
orc6
origin recognition complex, subunit 6
chr18_+_27511976 3.10 ENSDART00000132017
ENSDART00000140781
tp53i11b
tumor protein p53 inducible protein 11b
chr10_+_5954787 3.08 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
map3k1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr7_+_41812636 3.07 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr6_+_3717613 3.05 ENSDART00000184330
ssb
Sjogren syndrome antigen B (autoantigen La)
chr18_-_39787040 3.02 ENSDART00000169916
dmxl2
Dmx-like 2
chr6_-_17849786 3.02 ENSDART00000172709
rptor
regulatory associated protein of MTOR, complex 1
chr2_-_55779927 2.98 ENSDART00000168579
CABZ01066725.1

chr3_-_40051425 2.92 ENSDART00000146700
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr15_+_38299385 2.92 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr6_+_4255319 2.91 ENSDART00000170351
nbeal1
neurobeachin-like 1
chr11_+_44226200 2.89 ENSDART00000191417
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr5_-_69716501 2.87 ENSDART00000158956
mob1a
MOB kinase activator 1A
chr5_-_54712159 2.85 ENSDART00000149207
ccnb1
cyclin B1
chr17_+_24064014 2.84 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr20_-_34028967 2.83 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr6_+_10333920 2.82 ENSDART00000151667
ENSDART00000151477
cobll1a
cordon-bleu WH2 repeat protein-like 1a
chr16_+_40043673 2.77 ENSDART00000102552
ENSDART00000125484
trmt11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr18_+_27598755 2.72 ENSDART00000193808
cd82b
CD82 molecule b
chr25_-_25575241 2.67 ENSDART00000150636
hic1l
hypermethylated in cancer 1 like
chr3_+_19665319 2.65 ENSDART00000007857
ENSDART00000193509
mettl2a
methyltransferase like 2A
chr14_+_30285613 2.65 ENSDART00000173090
mtus1a
microtubule associated tumor suppressor 1a
chr14_-_34605804 2.64 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr15_-_31265375 2.63 ENSDART00000086592
vezf1b
vascular endothelial zinc finger 1b
chr8_-_22531817 2.62 ENSDART00000140606
csde1
cold shock domain containing E1, RNA-binding
chr13_+_7575563 2.61 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr21_-_25295087 2.60 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr4_+_4079418 2.57 ENSDART00000028016
waslb
Wiskott-Aldrich syndrome-like b
chr18_-_40753583 2.56 ENSDART00000026767
akt2
v-akt murine thymoma viral oncogene homolog 2
chr8_+_21254192 2.55 ENSDART00000167718
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr14_+_32918172 2.54 ENSDART00000182867
lnx2b
ligand of numb-protein X 2b
chr7_-_26601307 2.54 ENSDART00000188934
plscr3b
phospholipid scramblase 3b
chr2_-_15040345 2.53 ENSDART00000109657
si:dkey-10f21.4
si:dkey-10f21.4
chr8_-_52909850 2.52 ENSDART00000161943
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr13_+_25505580 2.50 ENSDART00000140634
inpp5f
inositol polyphosphate-5-phosphatase F
chr6_-_4214297 2.49 ENSDART00000191433
trak2
trafficking protein, kinesin binding 2
chr19_+_26072624 2.46 ENSDART00000147627
jarid2b
jumonji, AT rich interactive domain 2b
chr12_+_28955766 2.42 ENSDART00000123417
ENSDART00000139347
znf668
zinc finger protein 668
chr5_+_44655148 2.42 ENSDART00000124059
dapk1
death-associated protein kinase 1
chr5_-_29195063 2.42 ENSDART00000109926
man1b1b
mannosidase, alpha, class 1B, member 1b
chr15_-_16946124 2.39 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr19_-_43750389 2.39 ENSDART00000147328
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr7_+_24153070 2.39 ENSDART00000076735
lrp10
low density lipoprotein receptor-related protein 10
chr3_+_17939828 2.38 ENSDART00000185047
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr25_+_19870603 2.37 ENSDART00000047251
gramd4b
GRAM domain containing 4b
chr13_-_35765028 2.37 ENSDART00000157391
erlec1
endoplasmic reticulum lectin 1
chr9_-_11655031 2.37 ENSDART00000044314
itgav
integrin, alpha V
chr1_-_24349759 2.36 ENSDART00000142740
ENSDART00000177989
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr2_+_34112100 2.35 ENSDART00000056666
ENSDART00000146624
klhl20
kelch-like family member 20
chr6_-_40851499 2.34 ENSDART00000182591
rft1
RFT1 homolog
chr8_-_30424182 2.32 ENSDART00000099021
dock8
dedicator of cytokinesis 8
chr19_-_43750659 2.27 ENSDART00000151309
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr21_+_25765734 2.26 ENSDART00000021664
cldnb
claudin b
chr22_-_31517300 2.26 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr17_+_5931530 2.25 ENSDART00000168326
ENSDART00000189790
znf513b
zinc finger protein 513b
chr20_-_18789543 2.24 ENSDART00000182240
ccm2
cerebral cavernous malformation 2
chr23_-_21534738 2.24 ENSDART00000134587
rcc2
regulator of chromosome condensation 2
chr14_+_32918484 2.22 ENSDART00000105721
lnx2b
ligand of numb-protein X 2b
chr15_-_34865952 2.20 ENSDART00000186868
sh3bp5la
SH3-binding domain protein 5-like, a
chr23_-_36303216 2.20 ENSDART00000188720
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr2_+_3823813 2.19 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
npc1
Niemann-Pick disease, type C1
chr10_-_15879569 2.19 ENSDART00000136789
tjp2a
tight junction protein 2a (zona occludens 2)
chr15_+_20239141 2.18 ENSDART00000101152
ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr15_-_34866219 2.17 ENSDART00000099723
sh3bp5la
SH3-binding domain protein 5-like, a
chr3_-_36364903 2.17 ENSDART00000028883
gna13b
guanine nucleotide binding protein (G protein), alpha 13b
chr16_+_10329701 2.16 ENSDART00000172845
mdc1
mediator of DNA damage checkpoint 1
chr16_+_10330178 2.16 ENSDART00000121966
mdc1
mediator of DNA damage checkpoint 1
chr23_-_21534455 2.15 ENSDART00000139092
rcc2
regulator of chromosome condensation 2
chr9_-_28939181 2.15 ENSDART00000101276
ENSDART00000135334
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr9_-_30243393 2.14 ENSDART00000089539
si:dkey-100n23.3
si:dkey-100n23.3
chr5_+_872299 2.14 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr21_+_37513488 2.13 ENSDART00000185394
amot
angiomotin
chr5_+_40837539 2.13 ENSDART00000188279
si:dkey-3h3.3
si:dkey-3h3.3
chr2_+_27651984 2.13 ENSDART00000126762
tmem68
transmembrane protein 68
chr19_-_2085027 2.13 ENSDART00000063615
snx13
sorting nexin 13
chr2_-_4787566 2.12 ENSDART00000160663
ENSDART00000157808
tnk2b
tyrosine kinase, non-receptor, 2b
chr6_-_33871055 2.11 ENSDART00000115409
mast2
microtubule associated serine/threonine kinase 2
chr8_+_8643901 2.11 ENSDART00000142076
ENSDART00000075624
usp11
ubiquitin specific peptidase 11
chr1_+_12301913 2.10 ENSDART00000165733
gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr3_-_30909487 2.10 ENSDART00000025046
ppp1caa
protein phosphatase 1, catalytic subunit, alpha isozyme a
chr17_+_1544903 2.08 ENSDART00000156244
ENSDART00000112183
cep170b
centrosomal protein 170B
chr12_+_27232173 2.08 ENSDART00000193714
tmem106a
transmembrane protein 106A
chr21_+_37513058 2.06 ENSDART00000141096
amot
angiomotin
chr2_+_27652386 2.06 ENSDART00000188261
tmem68
transmembrane protein 68
chr2_-_27651674 2.04 ENSDART00000177402
tgs1
trimethylguanosine synthase 1
chr22_-_17652112 2.04 ENSDART00000189205
hmha1b
histocompatibility (minor) HA-1 b
chr6_+_612330 2.04 ENSDART00000166872
ENSDART00000191758
kynu
kynureninase
chr15_-_43284021 2.03 ENSDART00000041677
serpine2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr2_+_47489679 2.03 ENSDART00000074968
acsl3b
acyl-CoA synthetase long chain family member 3b
chr19_-_42503143 2.03 ENSDART00000007642
zgc:110239
zgc:110239
chr14_+_24840669 2.03 ENSDART00000106039
arhgef37
Rho guanine nucleotide exchange factor (GEF) 37
chr18_+_49969568 2.01 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr19_+_42086862 2.01 ENSDART00000151605
nfyc
nuclear transcription factor Y, gamma
chr18_+_45666489 2.01 ENSDART00000180147
ENSDART00000151351
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr16_+_47207691 1.99 ENSDART00000062507
ica1
islet cell autoantigen 1
chr11_+_24313931 1.99 ENSDART00000017599
ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr4_+_26056548 1.99 ENSDART00000171204
SCYL2
si:ch211-244b2.1
chr16_-_39241801 1.97 ENSDART00000171342
tmem42a
transmembrane protein 42a
chr23_-_21535040 1.96 ENSDART00000010647
rcc2
regulator of chromosome condensation 2
chr24_+_21174851 1.96 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr18_-_11595567 1.96 ENSDART00000098565
CRACR2A
calcium release activated channel regulator 2A
chr6_+_27992886 1.95 ENSDART00000160354
amotl2a
angiomotin like 2a
chr21_+_11923701 1.95 ENSDART00000109292
ubap2a
ubiquitin associated protein 2a
chr1_-_45213565 1.94 ENSDART00000145757
ddx39aa
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr9_-_20853439 1.93 ENSDART00000028247
ENSDART00000133321
gdap2
ganglioside induced differentiation associated protein 2
chr21_-_34972872 1.93 ENSDART00000023838
lipia
lipase, member Ia
chr6_+_37655078 1.92 ENSDART00000122199
ENSDART00000065127
cyfip1
cytoplasmic FMR1 interacting protein 1
chr12_-_13730501 1.92 ENSDART00000152370
foxh1
forkhead box H1
chr12_-_10508952 1.91 ENSDART00000152806
zgc:152977
zgc:152977
chr14_-_41478265 1.91 ENSDART00000149886
ENSDART00000016002
tspan7
tetraspanin 7
chr13_-_17943135 1.90 ENSDART00000176027
march8
membrane-associated ring finger (C3HC4) 8
chr7_+_26545502 1.89 ENSDART00000140528
tnk1
tyrosine kinase, non-receptor, 1
chr24_+_35911020 1.89 ENSDART00000088480
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr11_+_24314148 1.88 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr13_-_25745089 1.88 ENSDART00000189333
ENSDART00000147420
sgpl1
sphingosine-1-phosphate lyase 1
chr2_+_47708853 1.88 ENSDART00000124307
mbnl1
muscleblind-like splicing regulator 1
chr18_-_22094102 1.88 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr23_+_27779452 1.87 ENSDART00000134785
kmt2d
lysine (K)-specific methyltransferase 2D
chr22_-_37834312 1.87 ENSDART00000076128
ppp1r2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr9_+_33340311 1.86 ENSDART00000140064
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr24_-_31904924 1.83 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
si:ch73-78o10.1
chr6_-_10037207 1.81 ENSDART00000179701
nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr20_-_48898371 1.81 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr3_+_17933132 1.81 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr2_+_22363824 1.79 ENSDART00000163172
hs2st1a
heparan sulfate 2-O-sulfotransferase 1a
chr16_+_39242339 1.79 ENSDART00000102510
zgc:77056
zgc:77056
chr20_+_39250673 1.79 ENSDART00000153003
reps1
RALBP1 associated Eps domain containing 1
chr19_+_46222918 1.78 ENSDART00000158703
vps28
vacuolar protein sorting 28 (yeast)
chr11_-_4023940 1.77 ENSDART00000058728
ENSDART00000171245
nek4
NIMA-related kinase 4
chr5_+_15495351 1.76 ENSDART00000111646
ENSDART00000114446
suds3
SDS3 homolog, SIN3A corepressor complex component
chr13_-_42749916 1.75 ENSDART00000140019
capn2a
calpain 2, (m/II) large subunit a
chr24_+_21174523 1.75 ENSDART00000183849
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr18_+_3579829 1.75 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
lrch3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr17_-_11418513 1.75 ENSDART00000064412
ENSDART00000151847
arid4a
AT rich interactive domain 4A (RBP1-like)
chr13_-_33700461 1.74 ENSDART00000160520
mad2l1bp
MAD2L1 binding protein
chr7_-_28641522 1.74 ENSDART00000182071
slc7a6
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr24_-_16975960 1.74 ENSDART00000180687
klhl15
kelch-like family member 15
chr14_-_46616487 1.74 ENSDART00000105417
ENSDART00000166550
ENSDART00000105418
prom1a
prominin 1a
chr15_+_21711671 1.69 ENSDART00000136151
NKAPD1
zgc:162339
chr1_-_40519340 1.68 ENSDART00000114659
maml3
mastermind-like transcriptional coactivator 3
chr6_-_21616659 1.68 ENSDART00000074256
ppp1r12c
protein phosphatase 1, regulatory subunit 12C
chr21_+_21201346 1.67 ENSDART00000142961
rictorb
RPTOR independent companion of MTOR, complex 2b
chr6_-_55423220 1.67 ENSDART00000158929
ctsa
cathepsin A
chr5_-_65158203 1.67 ENSDART00000171656
sh2d3cb
SH2 domain containing 3Cb
chr2_-_37462462 1.67 ENSDART00000145896
si:dkey-57k2.7
si:dkey-57k2.7
chr20_+_38201644 1.66 ENSDART00000022694
ehd3
EH-domain containing 3
chr19_+_43523690 1.66 ENSDART00000113031
wasf2
WAS protein family, member 2
chr25_-_21507676 1.66 ENSDART00000010706
immp2l
inner mitochondrial membrane peptidase subunit 2
chr6_+_40554551 1.65 ENSDART00000017859
ENSDART00000155928
ddi2
DNA-damage inducible protein 2
chr5_-_29152457 1.65 ENSDART00000078469
noxa1
NADPH oxidase activator 1
chr16_-_32672883 1.65 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
pnisr
PNN-interacting serine/arginine-rich protein
chr17_-_26721007 1.64 ENSDART00000034580
calm1a
calmodulin 1a
chr16_+_3982590 1.64 ENSDART00000149295
zc3h12a
zinc finger CCCH-type containing 12A
chr10_-_28380919 1.63 ENSDART00000183409
ENSDART00000183105
ENSDART00000100207
ENSDART00000185392
ENSDART00000131220
btg3
B-cell translocation gene 3
chr19_-_11846958 1.62 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr2_-_24069331 1.62 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr21_+_13245302 1.62 ENSDART00000189498
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr12_-_4301234 1.61 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr22_+_24603930 1.60 ENSDART00000180240
ENSDART00000164256
CU655842.1

chr14_+_31473866 1.60 ENSDART00000173088
ccdc160
coiled-coil domain containing 160
chr12_-_17686404 1.59 ENSDART00000079065
ccz1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
chr5_-_56924747 1.58 ENSDART00000014028
ppm1db
protein phosphatase, Mg2+/Mn2+ dependent, 1Db
chr9_-_34842414 1.58 ENSDART00000126348
BX601644.1
Danio rerio cytokine receptor-like factor 2 (crlf2), mRNA.
chr19_+_2619444 1.58 ENSDART00000169483
fam126a
family with sequence similarity 126, member A
chr13_+_22719789 1.58 ENSDART00000057672
nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr23_+_19594608 1.57 ENSDART00000134865
slmapb
sarcolemma associated protein b
chr6_-_44161262 1.57 ENSDART00000035513
shq1
SHQ1, H/ACA ribonucleoprotein assembly factor
chr6_-_40713183 1.57 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr5_-_39171302 1.56 ENSDART00000020808
paqr3a
progestin and adipoQ receptor family member IIIa
chr22_+_30089054 1.56 ENSDART00000185369
add3a
adducin 3 (gamma) a
chr2_+_5406236 1.56 ENSDART00000154167
sft2d3
SFT2 domain containing 3
chr10_+_6907715 1.56 ENSDART00000041068
slc38a9
solute carrier family 38, member 9
chr23_-_18057851 1.54 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr4_+_13909398 1.54 ENSDART00000187959
ENSDART00000184926
pphln1
periphilin 1
chr18_+_45862414 1.54 ENSDART00000024615
rnpepl1
arginyl aminopeptidase like 1
chr3_-_21137362 1.54 ENSDART00000104051
cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr15_+_30310843 1.53 ENSDART00000112784
lyrm9
LYR motif containing 9
chr1_+_43686251 1.53 ENSDART00000074604
ENSDART00000137791
cisd2
CDGSH iron sulfur domain 2
chr21_+_43199237 1.52 ENSDART00000151748
aff4
AF4/FMR2 family, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of fli1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
1.3 5.2 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
1.0 3.0 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.9 3.7 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.8 2.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.8 3.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.8 3.9 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.8 6.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.7 2.2 GO:0006041 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.7 2.1 GO:0010657 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.6 2.6 GO:0046324 regulation of glucose import(GO:0046324)
0.6 4.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.6 2.4 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.5 1.6 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5 1.6 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.5 2.0 GO:0043420 ketone catabolic process(GO:0042182) anthranilate metabolic process(GO:0043420)
0.5 3.8 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.5 1.9 GO:0099563 modification of synaptic structure(GO:0099563)
0.5 1.9 GO:0048327 axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
0.5 1.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.4 5.4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.4 2.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.4 1.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.4 2.1 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.4 2.5 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.4 4.1 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.4 1.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 2.4 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.4 2.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.4 5.0 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.4 2.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.4 1.5 GO:0010259 multicellular organism aging(GO:0010259)
0.4 1.1 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.4 1.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.4 1.4 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.4 1.4 GO:0010668 ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.4 1.4 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.3 1.0 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.3 1.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 3.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.3 1.0 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.3 0.9 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.3 1.9 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.3 2.2 GO:0032570 response to progesterone(GO:0032570)
0.3 1.5 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.3 0.9 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.3 1.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.3 1.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.3 0.9 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.3 1.1 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.3 1.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 2.1 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.3 4.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 2.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 3.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 5.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.2 1.7 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 1.7 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 5.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.2 2.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 2.5 GO:0046548 retinal rod cell development(GO:0046548)
0.2 5.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.2 2.5 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.8 GO:0006203 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.2 1.8 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.2 1.3 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 1.3 GO:0006699 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.2 5.3 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.2 1.0 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.2 1.9 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.2 2.8 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 1.2 GO:0071800 podosome assembly(GO:0071800)
0.2 1.0 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 1.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.3 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 0.6 GO:0035973 aggrephagy(GO:0035973)
0.2 0.7 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 6.2 GO:0006270 DNA replication initiation(GO:0006270)
0.2 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.5 GO:1900180 regulation of protein localization to nucleus(GO:1900180) positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 0.7 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 1.6 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.2 1.0 GO:0032218 riboflavin transport(GO:0032218)
0.2 4.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.1 0.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 2.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 5.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.1 1.7 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 2.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.8 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 3.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.4 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 2.7 GO:0060021 palate development(GO:0060021)
0.1 2.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 2.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.6 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.1 1.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.3 GO:0009397 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.1 3.7 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 1.0 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 2.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 2.9 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 1.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.5 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.2 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.3 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.4 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.1 2.3 GO:0002097 tRNA wobble base modification(GO:0002097)
0.1 0.9 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 2.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.4 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 1.3 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 5.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 1.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.1 0.9 GO:2000142 regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) regulation of DNA-templated transcription, initiation(GO:2000142)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 1.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 2.5 GO:0055088 lipid homeostasis(GO:0055088)
0.1 3.3 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.7 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 1.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 2.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 1.3 GO:0048844 artery morphogenesis(GO:0048844)
0.1 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.1 2.6 GO:0001841 neural tube formation(GO:0001841)
0.1 1.0 GO:0061055 myotome development(GO:0061055)
0.1 2.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 2.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 2.3 GO:0072348 sulfur compound transport(GO:0072348)
0.1 1.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 2.6 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 5.6 GO:0001755 neural crest cell migration(GO:0001755)
0.1 1.9 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.2 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.2 GO:0071456 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.1 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.7 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 2.2 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.9 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.8 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.6 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 3.2 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 3.2 GO:0034968 histone lysine methylation(GO:0034968)
0.0 1.0 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.7 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.9 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 1.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 1.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 2.1 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.6 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.5 GO:0050926 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.7 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 1.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.7 GO:0031647 regulation of protein stability(GO:0031647)
0.0 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.0 1.0 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 2.9 GO:0031101 fin regeneration(GO:0031101)
0.0 2.2 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 2.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.6 GO:0003333 amino acid transmembrane transport(GO:0003333) organic acid transmembrane transport(GO:1903825) carboxylic acid transmembrane transport(GO:1905039)
0.0 0.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 1.4 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 1.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 2.4 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.6 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 1.4 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 2.9 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.9 GO:0000077 DNA damage checkpoint(GO:0000077)
0.0 2.1 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 1.2 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 1.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.5 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.3 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.0 0.0 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.4 GO:0007568 aging(GO:0007568)
0.0 0.1 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 1.5 GO:0016197 endosomal transport(GO:0016197)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.9 GO:0031018 endocrine pancreas development(GO:0031018)
0.0 0.0 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.0 0.6 GO:0035825 reciprocal DNA recombination(GO:0035825)
0.0 2.3 GO:0032259 methylation(GO:0032259)
0.0 1.0 GO:0006821 chloride transport(GO:0006821)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.9 2.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.8 3.0 GO:0043291 RAVE complex(GO:0043291)
0.7 3.7 GO:0031415 NatA complex(GO:0031415)
0.6 2.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.5 3.7 GO:1990130 Iml1 complex(GO:1990130)
0.5 1.6 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.5 3.6 GO:0035517 PR-DUB complex(GO:0035517)
0.5 6.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.5 4.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.5 7.0 GO:0002102 podosome(GO:0002102)
0.4 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 1.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.4 3.0 GO:0031931 TORC1 complex(GO:0031931)
0.4 3.2 GO:0031526 brush border membrane(GO:0031526)
0.3 1.7 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 3.6 GO:0045095 keratin filament(GO:0045095)
0.3 1.0 GO:0042382 paraspeckles(GO:0042382)
0.3 1.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.3 1.1 GO:0035339 SPOTS complex(GO:0035339)
0.2 0.9 GO:0016600 flotillin complex(GO:0016600)
0.2 3.6 GO:0031209 SCAR complex(GO:0031209)
0.2 1.7 GO:0071914 prominosome(GO:0071914)
0.2 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 1.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.2 1.2 GO:0005955 calcineurin complex(GO:0005955)
0.2 4.5 GO:0030667 secretory granule membrane(GO:0030667)
0.2 3.3 GO:0000813 ESCRT I complex(GO:0000813)
0.2 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.2 2.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 3.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 8.0 GO:0030496 midbody(GO:0030496)
0.2 1.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.9 GO:0031262 Ndc80 complex(GO:0031262)
0.1 18.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.7 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 2.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 2.5 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.1 1.0 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 4.9 GO:0016605 PML body(GO:0016605)
0.1 2.7 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.6 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 2.9 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 5.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.7 GO:0060170 ciliary membrane(GO:0060170)
0.1 4.7 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.1 0.7 GO:0032021 NELF complex(GO:0032021)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 3.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.6 GO:0005921 gap junction(GO:0005921)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.9 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 3.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 4.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 1.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.9 GO:0043209 myelin sheath(GO:0043209)
0.1 1.0 GO:0071004 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.1 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 4.2 GO:0030027 lamellipodium(GO:0030027)
0.0 5.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.9 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 1.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 4.8 GO:0016607 nuclear speck(GO:0016607)
0.0 1.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.0 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 2.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 3.6 GO:0005764 lysosome(GO:0005764)
0.0 0.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 3.4 GO:0005769 early endosome(GO:0005769)
0.0 1.1 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.2 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 2.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 5.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.2 GO:0005794 Golgi apparatus(GO:0005794)
0.0 0.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.9 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
1.1 3.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.9 3.5 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.8 2.5 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.7 2.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.7 3.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.7 2.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.7 2.8 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.7 2.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.6 1.8 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.5 1.9 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.5 1.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.5 2.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.4 4.1 GO:0035198 miRNA binding(GO:0035198)
0.3 1.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.3 1.3 GO:0047611 acetylspermidine deacetylase activity(GO:0047611)
0.3 2.7 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.3 1.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 1.0 GO:0047690 aspartyltransferase activity(GO:0047690)
0.3 2.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 4.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.3 1.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.3 0.9 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.3 0.9 GO:0032184 SUMO polymer binding(GO:0032184)
0.3 3.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 2.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 4.0 GO:0070403 NAD+ binding(GO:0070403)
0.3 0.8 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.3 1.5 GO:0008126 acetylesterase activity(GO:0008126)
0.2 2.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 2.4 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.2 5.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 2.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.2 0.7 GO:0043621 protein self-association(GO:0043621)
0.2 2.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 3.8 GO:0002039 p53 binding(GO:0002039)
0.2 2.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 0.8 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 4.0 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.2 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 2.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.0 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.2 1.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.6 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 4.5 GO:0005112 Notch binding(GO:0005112)
0.2 2.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.2 1.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.2 1.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 2.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 0.9 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.2 1.9 GO:0043495 protein anchor(GO:0043495)
0.2 1.8 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 1.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 1.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 2.5 GO:0045159 myosin II binding(GO:0045159)
0.1 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 3.6 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 3.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.0 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 8.0 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.0 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 3.3 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 1.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 2.5 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.1 8.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 3.0 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.1 10.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.9 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.0 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.4 GO:0051117 ATPase binding(GO:0051117)
0.1 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 1.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 1.5 GO:0035497 cAMP response element binding(GO:0035497)
0.1 5.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.2 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.0 GO:0005537 mannose binding(GO:0005537)
0.1 1.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.1 0.8 GO:0005042 netrin receptor activity(GO:0005042)
0.1 6.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.2 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 0.8 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 1.3 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.9 GO:0042287 MHC protein binding(GO:0042287)
0.1 0.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.7 GO:0008422 beta-glucosidase activity(GO:0008422)
0.1 0.2 GO:0004776 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 2.3 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.1 6.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 8.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.4 GO:0016896 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0 0.2 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 5.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 3.8 GO:0042802 identical protein binding(GO:0042802)
0.0 2.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.0 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 3.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 1.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.4 GO:0044325 ion channel binding(GO:0044325)
0.0 4.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.3 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 1.7 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 4.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 3.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 2.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 3.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 1.9 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 2.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 6.9 ST GAQ PATHWAY G alpha q Pathway
0.2 5.5 PID ATM PATHWAY ATM pathway
0.2 5.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.4 PID IFNG PATHWAY IFN-gamma pathway
0.1 1.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 8.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 2.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 4.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 1.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 4.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 3.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 2.0 PID AURORA B PATHWAY Aurora B signaling
0.1 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 1.8 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.4 2.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 1.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 7.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 2.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.3 3.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 3.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 2.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 2.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 5.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 2.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 2.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 1.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 4.7 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.2 2.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 2.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 1.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 2.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 3.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 4.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.9 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 1.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.6 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.6 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
0.1 1.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 7.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 3.5 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 2.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein