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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for fosaa+fosab+fosl1a

Z-value: 2.48

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Transcription factors associated with fosaa+fosab+fosl1a

Gene Symbol Gene ID Gene Info
fosl1a
ENSDARG00000015355 FOS-like antigen 1a
fosab
ENSDARG00000031683 v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
fosaa
ENSDARG00000040135 v-fos FBJ murine osteosarcoma viral oncogene homolog Aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fosl1adr11_v1_chr14_-_30747686_30747686-0.987.9e-13Click!
fosabdr11_v1_chr20_-_46554440_46554440-0.831.9e-05Click!
fosaadr11_v1_chr17_-_50234004_50234004-0.781.3e-04Click!

Activity profile of fosaa+fosab+fosl1a motif

Sorted Z-values of fosaa+fosab+fosl1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_60886984 23.85 ENSDART00000170974
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr2_-_17115256 9.50 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr1_-_33647138 9.03 ENSDART00000142111
ENSDART00000015547
cldng
claudin g
chr11_+_29537756 8.83 ENSDART00000103388
wu:fi42e03
wu:fi42e03
chr17_-_6514962 7.85 ENSDART00000163514
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr10_-_32877348 7.73 ENSDART00000018977
ENSDART00000133421
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1
chr18_+_45573416 7.30 ENSDART00000132184
ENSDART00000145288
kifc3
kinesin family member C3
chr24_+_10027902 7.03 ENSDART00000175961
ENSDART00000172773
si:ch211-146l10.8
si:ch211-146l10.8
chr3_+_7808459 6.39 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr24_-_10006158 5.85 ENSDART00000106244
zgc:171750
zgc:171750
chr22_-_5171362 5.82 ENSDART00000124889
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr8_-_2616326 5.71 ENSDART00000027214
slc25a25a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr22_-_5171829 5.59 ENSDART00000140313
tnfaip8l1
tumor necrosis factor, alpha-induced protein 8-like 1
chr19_+_14109348 5.48 ENSDART00000159015
zgc:175136
zgc:175136
chr7_-_33684632 5.47 ENSDART00000130553
tle3b
transducin-like enhancer of split 3b
chr10_+_39283985 5.40 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr19_+_791538 5.36 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr25_-_17918536 5.33 ENSDART00000148660
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr25_+_36292465 5.09 ENSDART00000152649
bmb
brambleberry
chr1_+_30723380 5.04 ENSDART00000127943
ENSDART00000062628
ENSDART00000127670
bora
bora, aurora kinase A activator
chr25_-_17918810 4.98 ENSDART00000023959
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr11_+_45287541 4.92 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr24_+_17334682 4.88 ENSDART00000018868
pdia4
protein disulfide isomerase family A, member 4
chr4_-_1720648 4.87 ENSDART00000103484
gas2l3
growth arrest-specific 2 like 3
chr24_-_9997948 4.82 ENSDART00000136274
si:ch211-146l10.7
si:ch211-146l10.7
chr6_-_25952848 4.72 ENSDART00000076997
ENSDART00000148748
lmo4b
LIM domain only 4b
chr1_+_30723677 4.70 ENSDART00000177900
bora
bora, aurora kinase A activator
chr5_-_54712159 4.70 ENSDART00000149207
ccnb1
cyclin B1
chr2_-_17114852 4.61 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr19_+_9111550 4.61 ENSDART00000088336
setdb1a
SET domain, bifurcated 1a
chr7_+_34794829 4.58 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr3_-_26191960 4.45 ENSDART00000113843
ypel3
yippee-like 3
chr7_+_30626378 4.45 ENSDART00000173533
ENSDART00000052541
ccnb2
cyclin B2
chr8_-_20230559 4.42 ENSDART00000193677
mllt1a
MLLT1, super elongation complex subunit a
chr12_+_13344896 4.36 ENSDART00000089017
rnasen
ribonuclease type III, nuclear
chr22_-_10539180 4.33 ENSDART00000131217
ippk
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr8_-_1219815 4.30 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr3_-_40054615 4.25 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr20_+_28266892 4.24 ENSDART00000103330
chac1
ChaC, cation transport regulator homolog 1 (E. coli)
chr11_-_10456387 4.22 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr24_-_9989634 4.18 ENSDART00000115275
zgc:152652
zgc:152652
chr23_+_36306539 4.16 ENSDART00000053267
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr13_+_8892784 4.14 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr10_-_39283883 4.11 ENSDART00000023831
cry5
cryptochrome circadian clock 5
chr21_+_13383413 4.10 ENSDART00000151345
zgc:113162
zgc:113162
chr16_+_54641230 4.10 ENSDART00000157641
ENSDART00000159540
fbxo43
F-box protein 43
chr1_-_54972170 4.08 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr22_-_11493236 4.03 ENSDART00000002691
tspan7b
tetraspanin 7b
chr15_-_31177324 4.02 ENSDART00000008854
wsb1
WD repeat and SOCS box containing 1
chr8_-_20230802 4.00 ENSDART00000063400
mllt1a
MLLT1, super elongation complex subunit a
chr11_-_10456553 3.98 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr8_+_16758304 3.97 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr1_+_12394205 3.96 ENSDART00000138622
ENSDART00000136421
ENSDART00000139440
ENSDART00000184296
ENSDART00000008127
zgc:77739
zgc:77739
chr8_-_16464453 3.95 ENSDART00000098691
rnf11b
ring finger protein 11b
chr21_-_41624697 3.93 ENSDART00000100039
pcyox1l
prenylcysteine oxidase 1 like
chr20_-_52939501 3.88 ENSDART00000166508
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr25_+_36292057 3.86 ENSDART00000152329
bmb
brambleberry
chr7_+_51805525 3.86 ENSDART00000026571
slc38a7
solute carrier family 38, member 7
chr24_-_9979342 3.83 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr5_-_1999417 3.82 ENSDART00000155437
ENSDART00000145781
si:ch211-160e1.5
si:ch211-160e1.5
chr18_+_45573251 3.80 ENSDART00000191309
kifc3
kinesin family member C3
chr10_+_16036573 3.79 ENSDART00000188757
lmnb1
lamin B1
chr22_-_817479 3.76 ENSDART00000123487
zgc:153675
zgc:153675
chr18_-_7031409 3.76 ENSDART00000148485
ENSDART00000005405
calub
calumenin b
chr14_+_1170968 3.68 ENSDART00000125203
ENSDART00000193575
hopx
HOP homeobox
chr13_-_18691041 3.66 ENSDART00000057867
sfxn3
sideroflexin 3
chr10_+_16036246 3.66 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr23_-_36305874 3.52 ENSDART00000147598
ENSDART00000146986
ENSDART00000086985
ENSDART00000133259
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr19_+_42328423 3.51 ENSDART00000077059
anp32e
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr21_-_32781612 3.49 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr17_+_24445818 3.43 ENSDART00000139963
ugp2b
UDP-glucose pyrophosphorylase 2b
chr23_-_893547 3.41 ENSDART00000136805
rbm10
RNA binding motif protein 10
chr5_-_72390259 3.41 ENSDART00000172302
wbp1
WW domain binding protein 1
chr9_+_32178050 3.39 ENSDART00000169526
coq10b
coenzyme Q10B
chr7_+_57088920 3.35 ENSDART00000024076
scamp2l
secretory carrier membrane protein 2, like
chr10_+_5268054 3.34 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr3_-_25377163 3.31 ENSDART00000055490
kpna2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_+_27691647 3.24 ENSDART00000079091
cyp2r1
cytochrome P450, family 2, subfamily R, polypeptide 1
chr25_+_30196039 3.21 ENSDART00000005299
hsd17b12a
hydroxysteroid (17-beta) dehydrogenase 12a
chr1_-_54971968 3.19 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr15_-_43287515 3.18 ENSDART00000155103
prss16
protease, serine, 16 (thymus)
chr19_-_34063567 3.16 ENSDART00000157815
ENSDART00000183907
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr2_-_55797318 3.14 ENSDART00000158147
calr3b
calreticulin 3b
chr23_-_36306337 3.14 ENSDART00000142760
ENSDART00000136929
ENSDART00000143340
cbx5
chromobox homolog 5 (HP1 alpha homolog, Drosophila)
chr18_+_3243292 3.10 ENSDART00000166580
pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr1_+_16600690 3.09 ENSDART00000162164
mtus1b
microtubule associated tumor suppressor 1b
chr9_-_30247961 3.09 ENSDART00000131519
si:dkey-100n23.3
si:dkey-100n23.3
chr7_-_48251234 3.09 ENSDART00000024062
ENSDART00000098904
cpeb1b
cytoplasmic polyadenylation element binding protein 1b
chr20_-_29498178 3.05 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
rrm2
ribonucleotide reductase M2 polypeptide
chr12_+_48340133 3.03 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr14_-_35892767 3.03 ENSDART00000052648
tmem144b
transmembrane protein 144b
chr19_-_2115040 3.02 ENSDART00000020497
snx13
sorting nexin 13
chr2_-_47620806 3.02 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr13_+_46941930 2.99 ENSDART00000056962
fbxo5
F-box protein 5
chr7_+_36467315 2.98 ENSDART00000138893
aktip
akt interacting protein
chr3_-_6417328 2.98 ENSDART00000160979
jpt1b
Jupiter microtubule associated homolog 1b
chr24_+_12835935 2.97 ENSDART00000114762
nanog
nanog homeobox
chr24_-_9991153 2.97 ENSDART00000137794
ENSDART00000106252
ENSDART00000188309
ENSDART00000188266
ENSDART00000188660
ENSDART00000185713
ENSDART00000179773
zgc:152652
zgc:152652
chr5_-_42180205 2.94 ENSDART00000145247
fam222ba
family with sequence similarity 222, member Ba
chr17_+_17804752 2.94 ENSDART00000123350
sptlc2a
serine palmitoyltransferase, long chain base subunit 2a
chr6_-_7686594 2.94 ENSDART00000091836
ENSDART00000151697
ubn2a
ubinuclein 2a
chr9_+_32178374 2.93 ENSDART00000078576
coq10b
coenzyme Q10B
chr5_+_37343643 2.91 ENSDART00000163993
ENSDART00000164459
ENSDART00000167006
ENSDART00000128122
ENSDART00000183720
klhl13
kelch-like family member 13
chr7_-_26518086 2.86 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr11_+_14321113 2.85 ENSDART00000039822
ENSDART00000137347
ENSDART00000132997
ptbp1b
polypyrimidine tract binding protein 1b
chr20_+_27749133 2.83 ENSDART00000089013
vrtn
vertebrae development associated
chr5_+_25733774 2.81 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr12_-_34827477 2.80 ENSDART00000153026
NDUFAF8
si:dkey-21c1.6
chr12_-_33359052 2.79 ENSDART00000135943
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr20_-_4793450 2.78 ENSDART00000053870
galca
galactosylceramidase a
chr2_-_40889465 2.78 ENSDART00000192631
ENSDART00000180824
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr5_-_10082244 2.74 ENSDART00000036421
chek2
checkpoint kinase 2
chr1_-_18811517 2.73 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr16_+_40043673 2.72 ENSDART00000102552
ENSDART00000125484
trmt11
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr16_+_50434668 2.71 ENSDART00000193500
IGLON5
zgc:110372
chr12_-_42368296 2.71 ENSDART00000171075
zgc:111868
zgc:111868
chr12_+_1469090 2.69 ENSDART00000183637
usp22
ubiquitin specific peptidase 22
chr3_-_60589292 2.68 ENSDART00000157822
jmjd6
jumonji domain containing 6
chr5_+_26213874 2.68 ENSDART00000193816
ENSDART00000098514
oclnb
occludin b
chr8_+_3649036 2.67 ENSDART00000033152
rab35b
RAB35, member RAS oncogene family b
chr8_+_54081819 2.65 ENSDART00000005857
ENSDART00000161795
prickle2a
prickle homolog 2a
chr12_-_10674606 2.63 ENSDART00000157919
med24
mediator complex subunit 24
chr16_-_6424816 2.62 ENSDART00000164864
ENSDART00000141860
mboat1
membrane bound O-acyltransferase domain containing 1
chr8_+_26868105 2.62 ENSDART00000005337
rimkla
ribosomal modification protein rimK-like family member A
chr13_+_11829072 2.61 ENSDART00000079356
ENSDART00000170160
sufu
suppressor of fused homolog (Drosophila)
chr6_-_23002373 2.61 ENSDART00000037709
ENSDART00000170369
nol11
nucleolar protein 11
chr2_-_37684641 2.61 ENSDART00000012191
hiat1a
hippocampus abundant transcript 1a
chr17_+_23556764 2.60 ENSDART00000146787
pank1a
pantothenate kinase 1a
chr3_-_33175583 2.57 ENSDART00000126022
rarab
retinoic acid receptor, alpha b
chr10_+_29770120 2.56 ENSDART00000100032
ENSDART00000193205
hyou1
hypoxia up-regulated 1
chr1_-_9527200 2.56 ENSDART00000110790
si:ch73-12o23.1
si:ch73-12o23.1
chr6_-_14040136 2.55 ENSDART00000065361
ENSDART00000179765
etv5b
ets variant 5b
chr16_-_13680692 2.54 ENSDART00000047452
ube2s
ubiquitin-conjugating enzyme E2S
chr22_-_4439311 2.54 ENSDART00000169317
uhrf1
ubiquitin-like with PHD and ring finger domains 1
chr8_-_1266181 2.54 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr8_+_1009831 2.52 ENSDART00000172414
fabp1b.2
fatty acid binding protein 1b, liver, tandem duplicate 2
chr4_-_16876281 2.51 ENSDART00000016690
ENSDART00000044005
ENSDART00000042874
ENSDART00000125762
ENSDART00000185974
tmpoa
thymopoietin a
chr22_-_20419660 2.51 ENSDART00000105520
pias4a
protein inhibitor of activated STAT, 4a
chr19_-_15420678 2.50 ENSDART00000151454
ENSDART00000027697
serinc2
serine incorporator 2
chr3_+_1167026 2.48 ENSDART00000031823
ENSDART00000155340
triobpb
TRIO and F-actin binding protein b
chr9_+_45227028 2.48 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr6_-_1820606 2.48 ENSDART00000183228
FO834857.1

chr3_-_30909487 2.48 ENSDART00000025046
ppp1caa
protein phosphatase 1, catalytic subunit, alpha isozyme a
chr13_-_36050303 2.47 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr15_+_38299563 2.47 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr19_-_31686252 2.43 ENSDART00000131721
ripor2
RHO family interacting cell polarization regulator 2
chr18_+_39416357 2.43 ENSDART00000183174
ENSDART00000127955
ENSDART00000171303
lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr6_+_612330 2.42 ENSDART00000166872
ENSDART00000191758
kynu
kynureninase
chr16_+_39159752 2.38 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr5_+_44804791 2.38 ENSDART00000122288
ctsla
cathepsin La
chr15_+_25438714 2.37 ENSDART00000154164
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr1_+_6135176 2.37 ENSDART00000092324
ENSDART00000179970
abcb6a
ATP-binding cassette, sub-family B (MDR/TAP), member 6a
chr11_+_45153104 2.37 ENSDART00000159204
ENSDART00000177585
tk1
thymidine kinase 1, soluble
chr10_-_35257458 2.37 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr22_-_3299100 2.36 ENSDART00000160305
si:zfos-943e10.1
si:zfos-943e10.1
chr16_-_25680666 2.36 ENSDART00000132693
ENSDART00000140539
ENSDART00000015302
tomm40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr8_+_16738282 2.36 ENSDART00000134265
ENSDART00000100698
ercc8
excision repair cross-complementation group 8
chr18_+_20047374 2.35 ENSDART00000146957
uacaa
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr15_+_15258758 2.34 ENSDART00000155719
c2cd3
C2 calcium-dependent domain containing 3
chr19_+_33464688 2.33 ENSDART00000142275
triqk
triple QxxK/R motif containing
chr14_-_246342 2.33 ENSDART00000054823
aurkb
aurora kinase B
chr3_-_49514874 2.33 ENSDART00000167179
asf1ba
anti-silencing function 1Ba histone chaperone
chr6_-_9676108 2.33 ENSDART00000169915
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr2_-_17492080 2.32 ENSDART00000024302
kdm4ab
lysine (K)-specific demethylase 4A, genome duplicate b
chr17_+_19481049 2.31 ENSDART00000024194
kif11
kinesin family member 11
chr20_-_10487951 2.31 ENSDART00000064112
glrx5
glutaredoxin 5 homolog (S. cerevisiae)
chr10_+_6010570 2.30 ENSDART00000190025
ENSDART00000163680
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr18_+_27489595 2.30 ENSDART00000182018
tp53i11b
tumor protein p53 inducible protein 11b
chr10_-_7821686 2.28 ENSDART00000121531
mat2aa
methionine adenosyltransferase II, alpha a
chr18_+_16053455 2.27 ENSDART00000189163
ENSDART00000188269
FO834850.1

chr15_-_44052927 2.26 ENSDART00000166209
wu:fb44b02
wu:fb44b02
chr22_+_15960005 2.26 ENSDART00000033617
stil
scl/tal1 interrupting locus
chr18_+_14307059 2.25 ENSDART00000186558
zgc:173742
zgc:173742
chr4_+_76311161 2.25 ENSDART00000167988
si:ch73-389k6.1
si:ch73-389k6.1
chr5_-_54714525 2.23 ENSDART00000150138
ENSDART00000150070
ccnb1
cyclin B1
chr5_+_15992655 2.22 ENSDART00000182148
znrf3
zinc and ring finger 3
chr5_-_23596339 2.21 ENSDART00000024815
fam76b
family with sequence similarity 76, member B
chr20_+_23501535 2.21 ENSDART00000177922
ENSDART00000058532
palld
palladin, cytoskeletal associated protein
chr1_-_48933 2.20 ENSDART00000171162
ildr1a
immunoglobulin-like domain containing receptor 1a
chr25_-_2723902 2.19 ENSDART00000143721
ENSDART00000175224
adpgk
ADP-dependent glucokinase
chr22_+_15959844 2.18 ENSDART00000182201
stil
scl/tal1 interrupting locus
chr13_-_25198025 2.17 ENSDART00000159585
ENSDART00000144227
adka
adenosine kinase a
chr6_+_60112200 2.17 ENSDART00000008243
prelid3b
PRELI domain containing 3
chr1_+_54737353 2.17 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr25_-_2723682 2.17 ENSDART00000113382
adpgk
ADP-dependent glucokinase
chr3_+_16664212 2.17 ENSDART00000013816
zgc:55558
zgc:55558
chr5_-_54714789 2.16 ENSDART00000063357
ccnb1
cyclin B1
chr18_-_35407695 2.16 ENSDART00000191845
ENSDART00000141703
snrpa
small nuclear ribonucleoprotein polypeptide A
chr17_+_19626479 2.16 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr18_-_35407530 2.15 ENSDART00000137663
snrpa
small nuclear ribonucleoprotein polypeptide A
chr18_-_25051846 2.15 ENSDART00000013082
st8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr1_+_43686251 2.14 ENSDART00000074604
ENSDART00000137791
cisd2
CDGSH iron sulfur domain 2
chr22_-_3299355 2.14 ENSDART00000190993
si:zfos-943e10.1
si:zfos-943e10.1
chr23_-_10786400 2.13 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr13_-_51846224 2.13 ENSDART00000184663
LT631684.2

chr10_+_29771256 2.12 ENSDART00000193195
hyou1
hypoxia up-regulated 1
chr7_-_33868903 2.12 ENSDART00000173500
ENSDART00000178746
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr2_-_39675829 2.12 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr15_+_25439106 2.11 ENSDART00000156252
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr8_-_39884359 2.11 ENSDART00000131372
mlec
malectin

Network of associatons between targets according to the STRING database.

First level regulatory network of fosaa+fosab+fosl1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 9.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
1.8 9.0 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
1.5 4.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.2 14.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
1.1 5.5 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
1.1 4.3 GO:0052746 inositol phosphorylation(GO:0052746)
1.0 3.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
1.0 9.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.0 3.0 GO:0010658 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.9 1.9 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.9 7.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.9 2.6 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.9 1.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.8 11.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.8 2.4 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.8 2.4 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.8 9.5 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.8 2.3 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.8 6.2 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.8 5.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.8 3.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.7 2.2 GO:0019408 dolichol biosynthetic process(GO:0019408)
0.7 4.9 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.7 3.4 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.7 2.7 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.7 2.6 GO:1900181 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.6 3.7 GO:0003232 bulbus arteriosus development(GO:0003232)
0.6 3.1 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.6 2.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.6 2.4 GO:0043420 ketone catabolic process(GO:0042182) anthranilate metabolic process(GO:0043420)
0.6 2.4 GO:0060074 synapse maturation(GO:0060074)
0.6 2.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.6 2.2 GO:0032801 receptor catabolic process(GO:0032801)
0.5 3.2 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.5 2.1 GO:0010259 multicellular organism aging(GO:0010259)
0.5 3.7 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.5 1.6 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.5 1.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.5 4.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.5 2.4 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.5 2.4 GO:0061072 iris morphogenesis(GO:0061072)
0.5 9.3 GO:0007032 endosome organization(GO:0007032)
0.5 1.4 GO:0071922 regulation of sister chromatid cohesion(GO:0007063) regulation of chromosome condensation(GO:0060623) regulation of cohesin loading(GO:0071922)
0.4 1.8 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.4 3.1 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.4 2.6 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.4 4.8 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 3.9 GO:0006167 AMP biosynthetic process(GO:0006167)
0.4 4.8 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.4 1.3 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.4 0.4 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4 6.8 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.4 2.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 1.7 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.4 2.5 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.4 1.3 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.4 0.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.4 2.1 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.4 13.8 GO:0009648 photoperiodism(GO:0009648)
0.4 3.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.4 1.6 GO:0006531 aspartate metabolic process(GO:0006531)
0.4 1.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.4 4.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.4 3.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.4 2.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.4 0.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.4 1.5 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.4 2.9 GO:0034475 U4 snRNA 3'-end processing(GO:0034475)
0.4 1.4 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.4 2.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.4 4.6 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.4 2.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.3 2.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.3 0.7 GO:0009139 pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139)
0.3 1.7 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.3 2.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 1.7 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.3 2.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.3 2.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3 9.1 GO:0031100 organ regeneration(GO:0031100)
0.3 14.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.3 1.2 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.3 0.9 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.3 4.8 GO:0016926 protein desumoylation(GO:0016926)
0.3 2.1 GO:0036010 protein localization to endosome(GO:0036010)
0.3 4.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.3 1.7 GO:0035889 otolith tethering(GO:0035889)
0.3 4.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.3 2.0 GO:0009303 rRNA transcription(GO:0009303)
0.3 1.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 1.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 1.1 GO:0040016 embryonic cleavage(GO:0040016)
0.3 2.2 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.3 0.8 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.3 2.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.3 3.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 2.9 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.3 1.6 GO:0060876 semicircular canal formation(GO:0060876)
0.3 0.5 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.3 0.8 GO:0036315 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 1.9 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.3 1.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.3 2.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 1.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.3 1.3 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 1.0 GO:0001715 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.2 2.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.2 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2 2.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.2 3.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.2 1.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 1.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 2.4 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.2 2.8 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 0.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 1.7 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.2 2.6 GO:0003139 secondary heart field specification(GO:0003139)
0.2 1.3 GO:0007100 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.2 1.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.2 2.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.2 2.1 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.2 3.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 0.8 GO:0021516 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.2 2.4 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 2.2 GO:0046548 retinal rod cell development(GO:0046548)
0.2 0.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 1.4 GO:0071623 negative regulation of leukocyte migration(GO:0002686) negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.2 5.9 GO:0036294 cellular response to decreased oxygen levels(GO:0036294)
0.2 1.7 GO:0006901 vesicle coating(GO:0006901)
0.2 10.9 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.2 0.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 1.5 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.2 2.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 1.5 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 0.7 GO:0034627 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.2 1.3 GO:0007584 response to nutrient(GO:0007584)
0.2 1.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.2 0.5 GO:0030521 androgen receptor signaling pathway(GO:0030521) regulation of androgen receptor signaling pathway(GO:0060765)
0.2 1.6 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.2 3.9 GO:0043486 histone exchange(GO:0043486)
0.2 1.4 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.2 2.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.2 4.9 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.2 1.0 GO:0003272 endocardial cushion formation(GO:0003272)
0.2 0.8 GO:0070650 actin filament bundle distribution(GO:0070650)
0.2 2.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 0.5 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.2 0.8 GO:0034505 tooth mineralization(GO:0034505)
0.2 0.8 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.6 GO:0031053 primary miRNA processing(GO:0031053)
0.2 1.0 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.2 1.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 0.5 GO:0044320 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.2 0.5 GO:0097676 histone H3-K4 trimethylation(GO:0080182) histone H3-K36 dimethylation(GO:0097676)
0.2 2.6 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.1 3.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.0 GO:0030728 ovulation(GO:0030728)
0.1 0.7 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.4 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 1.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 5.4 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.6 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.7 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.1 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.5 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 3.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 0.5 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 1.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 0.4 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 1.1 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.1 1.1 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.6 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551) regulation of phospholipid metabolic process(GO:1903725)
0.1 1.2 GO:0070307 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 3.1 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.1 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.6 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.8 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.3 GO:0006565 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.1 0.4 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 1.9 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.9 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 1.0 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 3.1 GO:0051225 spindle assembly(GO:0051225)
0.1 0.4 GO:0060406 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.1 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.2 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.1 17.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.1 2.4 GO:0060541 respiratory system development(GO:0060541)
0.1 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.7 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.6 GO:0071800 podosome assembly(GO:0071800)
0.1 1.3 GO:0007260 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 3.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 2.1 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 3.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.5 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 1.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 5.8 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1 1.8 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.1 1.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.0 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.6 GO:0097178 ruffle assembly(GO:0097178)
0.1 0.3 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 3.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 1.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.2 GO:0098924 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.1 0.2 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 2.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 1.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.2 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 4.4 GO:0034249 negative regulation of translation(GO:0017148) negative regulation of cellular amide metabolic process(GO:0034249)
0.1 1.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.8 GO:0009060 aerobic respiration(GO:0009060)
0.1 3.6 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.7 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.5 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.6 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.4 GO:0090497 mesenchymal cell migration(GO:0090497)
0.1 1.8 GO:0007340 acrosome reaction(GO:0007340)
0.1 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.1 3.6 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.1 0.5 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.8 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174) negative regulation of metaphase/anaphase transition of cell cycle(GO:1902100)
0.1 2.9 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.9 GO:0035476 angioblast cell migration(GO:0035476)
0.1 4.0 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.1 0.7 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.1 0.3 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.1 GO:0048477 oogenesis(GO:0048477)
0.0 2.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 5.7 GO:0006909 phagocytosis(GO:0006909)
0.0 2.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 1.5 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:1904427 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of calcium ion transmembrane transport(GO:1904427)
0.0 2.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 1.1 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.6 GO:0014823 response to activity(GO:0014823)
0.0 1.2 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.6 GO:0060324 face development(GO:0060324)
0.0 0.8 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.6 GO:0002063 chondrocyte development(GO:0002063)
0.0 2.8 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.9 GO:0043038 amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 0.3 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 2.0 GO:0006096 glycolytic process(GO:0006096)
0.0 0.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.2 GO:0043489 RNA stabilization(GO:0043489)
0.0 2.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 1.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate metabolic process(GO:0009256) 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.9 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 2.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0016446 meiotic mismatch repair(GO:0000710) somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 1.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.6 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534) homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.0 1.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:0042476 odontogenesis(GO:0042476)
0.0 2.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 3.9 GO:0045055 regulated exocytosis(GO:0045055)
0.0 3.7 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.2 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.6 GO:0006506 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0061550 cranial ganglion development(GO:0061550)
0.0 0.4 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 3.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.4 GO:0097306 cellular response to alcohol(GO:0097306)
0.0 0.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.1 GO:0039694 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.0 1.5 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 1.9 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 1.7 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.5 GO:1903038 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 1.2 GO:0048916 posterior lateral line development(GO:0048916)
0.0 1.1 GO:0071482 cellular response to light stimulus(GO:0071482)
0.0 4.6 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.4 GO:0001757 somite specification(GO:0001757)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0072350 citrate metabolic process(GO:0006101) tricarboxylic acid metabolic process(GO:0072350)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 1.0 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.9 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.1 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.3 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.6 GO:0007030 Golgi organization(GO:0007030)
0.0 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.8 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.0 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.1 GO:0050890 cognition(GO:0050890)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of chromosome segregation(GO:0051984) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.0 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.5 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.3 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.6 4.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.2 7.5 GO:0070695 FHF complex(GO:0070695)
0.9 2.7 GO:0098536 deuterosome(GO:0098536)
0.7 4.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.7 2.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.7 2.6 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.6 8.8 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.6 1.8 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.6 2.4 GO:0060171 stereocilium membrane(GO:0060171)
0.6 2.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.6 2.3 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.6 1.7 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.5 1.0 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.5 2.0 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.5 1.9 GO:0005880 nuclear microtubule(GO:0005880)
0.4 8.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.4 3.0 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.4 0.4 GO:0034709 methylosome(GO:0034709)
0.4 4.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.4 2.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.4 2.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.4 8.5 GO:0005685 U1 snRNP(GO:0005685)
0.4 1.8 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.4 3.5 GO:0000812 Swr1 complex(GO:0000812)
0.4 3.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 3.1 GO:0070652 HAUS complex(GO:0070652)
0.3 18.2 GO:0005657 replication fork(GO:0005657)
0.3 2.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3 1.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 1.0 GO:0030689 Noc complex(GO:0030689)
0.3 1.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.3 1.6 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.3 14.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 4.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.3 2.0 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3 3.3 GO:0016580 Sin3 complex(GO:0016580)
0.3 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 2.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 2.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 0.8 GO:0043291 RAVE complex(GO:0043291)
0.2 1.8 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 1.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.7 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 0.5 GO:0097361 CIA complex(GO:0097361)
0.2 0.5 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.3 GO:0071914 prominosome(GO:0071914)
0.2 1.0 GO:0070876 SOSS complex(GO:0070876)
0.2 1.7 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.2 1.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.2 GO:0000796 condensin complex(GO:0000796)
0.1 3.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.5 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.8 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 2.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.8 GO:0071256 translocon complex(GO:0071256)
0.1 5.1 GO:0031941 filamentous actin(GO:0031941)
0.1 1.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 2.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.6 GO:0030891 VCB complex(GO:0030891)
0.1 0.6 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.8 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 3.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 7.8 GO:0005795 Golgi stack(GO:0005795)
0.1 10.2 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 5.4 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 3.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 3.5 GO:0030175 filopodium(GO:0030175)
0.1 1.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 18.0 GO:0005730 nucleolus(GO:0005730)
0.1 1.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 6.6 GO:0005882 intermediate filament(GO:0005882)
0.1 1.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.1 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.5 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.5 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 5.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 4.3 GO:0005871 kinesin complex(GO:0005871)
0.0 2.6 GO:0005774 vacuolar membrane(GO:0005774)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 2.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.5 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 2.0 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 6.3 GO:0010008 endosome membrane(GO:0010008)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 2.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.6 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 2.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 4.9 GO:0005938 cell cortex(GO:0005938)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 3.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 2.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 3.8 GO:0005764 lysosome(GO:0005764)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 4.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 1.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.5 GO:0030135 coated vesicle(GO:0030135)
0.0 7.2 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 14.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
1.4 4.1 GO:0003913 DNA photolyase activity(GO:0003913)
1.4 5.5 GO:0071889 14-3-3 protein binding(GO:0071889)
1.3 3.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
1.3 3.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
1.3 3.9 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
1.1 5.5 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
1.0 10.4 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.9 3.7 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.9 4.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.9 2.7 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.9 4.5 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.9 2.6 GO:0072591 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.9 3.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.8 6.8 GO:0030619 U1 snRNA binding(GO:0030619)
0.8 2.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.7 6.3 GO:0048039 ubiquinone binding(GO:0048039)
0.7 2.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.7 2.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.7 3.4 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.7 4.8 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.7 2.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.7 5.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.6 2.6 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.6 2.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.6 4.1 GO:0035173 histone kinase activity(GO:0035173)
0.6 2.9 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.6 2.3 GO:0045547 dehydrodolichyl diphosphate synthase activity(GO:0045547)
0.5 8.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.5 4.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 2.0 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.5 4.0 GO:0015232 heme transporter activity(GO:0015232)
0.4 5.8 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.4 2.6 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.4 2.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.4 2.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.4 2.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.4 1.3 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.4 1.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 3.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.4 1.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.4 3.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.4 1.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.4 1.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.3 1.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 11.2 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.3 3.0 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 1.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.3 2.3 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.3 2.0 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 4.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 2.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.3 1.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.3 2.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 2.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.3 2.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.3 1.2 GO:0097157 U12 snRNA binding(GO:0030626) pre-mRNA intronic binding(GO:0097157)
0.3 9.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 0.9 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.3 2.0 GO:0008312 7S RNA binding(GO:0008312)
0.3 1.1 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 2.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 2.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.3 0.8 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.3 1.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.3 1.8 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 0.7 GO:0004061 arylformamidase activity(GO:0004061)
0.2 0.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 3.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.2 2.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.2 0.7 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 3.7 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.2 1.1 GO:0043295 glutathione binding(GO:0043295)
0.2 3.8 GO:0045159 myosin II binding(GO:0045159)
0.2 2.0 GO:0004096 catalase activity(GO:0004096)
0.2 0.7 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 1.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.2 2.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 0.6 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.6 GO:0098808 mRNA cap binding(GO:0098808)
0.2 2.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 3.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 1.5 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 7.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 0.7 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.2 1.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 1.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 2.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.2 1.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 0.6 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 3.0 GO:0030515 snoRNA binding(GO:0030515)
0.2 1.4 GO:0051920 peroxiredoxin activity(GO:0051920)
0.2 7.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.2 1.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.2 0.6 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 2.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 2.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 1.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 2.3 GO:0016896 3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.1 1.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.9 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 2.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 4.4 GO:0019003 GDP binding(GO:0019003)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 2.1 GO:0002039 p53 binding(GO:0002039)
0.1 3.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.6 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 5.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 2.1 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.8 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 1.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 1.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.9 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.9 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 1.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 3.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.3 GO:0005123 death receptor binding(GO:0005123)
0.1 1.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 7.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 10.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0043495 protein anchor(GO:0043495)
0.1 1.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.0 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 6.2 GO:0051082 unfolded protein binding(GO:0051082)
0.1 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 5.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 3.4 GO:0003777 microtubule motor activity(GO:0003777)
0.1 2.2 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.4 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.0 GO:0019894 kinesin binding(GO:0019894)
0.1 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 17.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 2.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 4.1 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.7 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 11.4 GO:0042802 identical protein binding(GO:0042802)
0.1 3.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 1.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 2.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 1.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 1.9 GO:0071949 FAD binding(GO:0071949)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 5.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 1.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 6.8 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 1.3 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.9 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.5 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 3.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.9 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.1 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 9.4 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 6.8 GO:0051015 actin filament binding(GO:0051015)
0.0 1.2 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.5 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.7 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.7 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.6 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 2.0 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 6.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.3 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 39.1 PID PLK1 PATHWAY PLK1 signaling events
0.6 2.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.5 17.3 PID AURORA B PATHWAY Aurora B signaling
0.4 2.6 PID ATM PATHWAY ATM pathway
0.4 13.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 3.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.3 10.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.3 14.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 3.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 5.7 PID RAS PATHWAY Regulation of Ras family activation
0.2 1.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 7.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 4.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 3.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.0 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 4.1 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 1.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.8 PID BARD1 PATHWAY BARD1 signaling events
0.1 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 1.5 PID FOXO PATHWAY FoxO family signaling
0.1 2.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 0.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 1.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
1.4 4.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.9 7.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.8 14.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7 7.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5 2.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.5 3.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.5 9.3 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.4 2.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.4 2.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 8.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.4 4.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.3 2.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 13.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 1.5 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.3 8.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.3 6.1 REACTOME KINESINS Genes involved in Kinesins
0.3 1.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.3 1.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 3.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 2.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 3.5 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 2.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 1.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 2.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 2.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 3.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 4.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.1 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 3.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 3.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 1.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 4.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 2.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 10.8 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 6.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 2.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 2.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.7 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 2.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 0.6 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 0.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 2.4 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.6 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 6.1 REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION Genes involved in Class I MHC mediated antigen processing & presentation
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.3 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.8 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production