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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for fosb+fosl2+si:ch211-153j24.3

Z-value: 0.85

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Transcription factors associated with fosb+fosl2+si:ch211-153j24.3

Gene Symbol Gene ID Gene Info
fosl2
ENSDARG00000040623 fos-like antigen 2
fosb
ENSDARG00000055751 FBJ murine osteosarcoma viral oncogene homolog B
si_ch211-153j24.3
ENSDARG00000068428 si_ch211-153j24.3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
fosbdr11_v1_chr18_+_36770166_367701660.911.5e-07Click!
fosl2dr11_v1_chr17_+_41302660_413026600.814.3e-05Click!
si:ch211-153j24.3dr11_v1_chr20_+_46560258_465602580.522.5e-02Click!

Activity profile of fosb+fosl2+si:ch211-153j24.3 motif

Sorted Z-values of fosb+fosl2+si:ch211-153j24.3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_46382484 3.49 ENSDART00000024202
ENSDART00000142790
daw1
dynein assembly factor with WDR repeat domains 1
chr12_-_212843 3.47 ENSDART00000083574
CABZ01102039.1

chr11_-_24681292 3.30 ENSDART00000089601
olfml3b
olfactomedin-like 3b
chr10_+_31222656 2.48 ENSDART00000140988
ENSDART00000143387
tmem218
transmembrane protein 218
chr16_+_42829735 2.39 ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr24_+_31361407 2.26 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr10_+_31222433 1.93 ENSDART00000185080
tmem218
transmembrane protein 218
chr2_+_17524278 1.85 ENSDART00000165633
pimr196
Pim proto-oncogene, serine/threonine kinase, related 196
chr5_-_21888368 1.83 ENSDART00000020725
smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr3_-_61593274 1.73 ENSDART00000154132
ENSDART00000055071
nptx2a
neuronal pentraxin 2a
chr21_-_30545121 1.65 ENSDART00000019199
rab39ba
RAB39B, member RAS oncogene family a
chr1_-_52498146 1.64 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr7_-_52963493 1.53 ENSDART00000052029
cart3
cocaine- and amphetamine-regulated transcript 3
chr21_+_22828500 1.52 ENSDART00000151109
si:rp71-1p14.7
si:rp71-1p14.7
chr9_-_27805801 1.51 ENSDART00000140608
ENSDART00000114542
si:rp71-45g20.10
si:rp71-45g20.10
chr12_+_8074343 1.50 ENSDART00000124084
cabcoco1
ciliary associated calcium binding coiled-coil 1
chr23_-_39636195 1.49 ENSDART00000144439
vwa1
von Willebrand factor A domain containing 1
chr1_+_44360973 1.40 ENSDART00000167568
si:ch211-165a10.5
si:ch211-165a10.5
chr16_+_42830152 1.40 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr10_+_26747755 1.30 ENSDART00000100329
f9b
coagulation factor IXb
chr10_-_27566481 1.27 ENSDART00000078920
auts2a
autism susceptibility candidate 2a
chr16_-_13818061 1.26 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr6_+_29791164 1.25 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr23_-_37113396 1.25 ENSDART00000102886
ENSDART00000134461
zgc:193690
zgc:193690
chr3_+_24986145 1.24 ENSDART00000055428
cbx7a
chromobox homolog 7a
chr16_+_41517188 1.23 ENSDART00000049976
si:dkey-11p23.7
si:dkey-11p23.7
chr16_+_23960744 1.23 ENSDART00000058965
apoeb
apolipoprotein Eb
chr10_+_4987766 1.17 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr22_+_25049563 1.16 ENSDART00000078173
dzank1
double zinc ribbon and ankyrin repeat domains 1
chr1_-_59411901 1.14 ENSDART00000167015
si:ch211-188p14.4
si:ch211-188p14.4
chr12_+_20506197 1.14 ENSDART00000153010
si:zfos-754c12.2
si:zfos-754c12.2
chr17_+_7524389 1.14 ENSDART00000067579
klhl10b.2
kelch-like family member 10b, tandem duplicate 2
chr3_+_24197934 1.13 ENSDART00000055609
atf4b
activating transcription factor 4b
chr1_-_52497834 1.13 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr7_-_25697285 1.13 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr25_+_4954220 1.11 ENSDART00000156034
si:ch73-265h17.2
si:ch73-265h17.2
chr2_+_48288461 1.10 ENSDART00000141495
hes6
hes family bHLH transcription factor 6
chr24_+_38522254 1.07 ENSDART00000156189
si:ch1073-66l23.1
si:ch1073-66l23.1
chr23_-_37113215 1.06 ENSDART00000146835
zgc:193690
zgc:193690
chr13_+_50368668 1.04 ENSDART00000127610
dnajc12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr1_+_44249616 0.99 ENSDART00000164173
si:ch211-165a10.10
si:ch211-165a10.10
chr2_-_17828279 0.98 ENSDART00000083314
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr17_+_6667441 0.97 ENSDART00000123503
ENSDART00000180381
ENSDART00000156140
smc6
structural maintenance of chromosomes 6
chr2_-_17827983 0.97 ENSDART00000166518
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr4_-_14915268 0.94 ENSDART00000067040
si:dkey-180p18.9
si:dkey-180p18.9
chr1_+_2190714 0.94 ENSDART00000132126
mbnl2
muscleblind-like splicing regulator 2
chr3_+_26064091 0.92 ENSDART00000143697
si:dkeyp-69e1.8
si:dkeyp-69e1.8
chr2_-_39759059 0.89 ENSDART00000007333
slc25a36a
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr19_+_23932259 0.89 ENSDART00000139040
si:dkey-222b8.1
si:dkey-222b8.1
chr2_+_17540720 0.87 ENSDART00000114638
pimr198
Pim proto-oncogene, serine/threonine kinase, related 198
chr22_-_10110959 0.87 ENSDART00000031005
ENSDART00000147580
gls2b
glutaminase 2b (liver, mitochondrial)
chr23_-_42752387 0.87 ENSDART00000149781
si:ch73-217n20.1
si:ch73-217n20.1
chr9_-_27771339 0.83 ENSDART00000135722
ENSDART00000140381
si:rp71-45g20.11
si:rp71-45g20.11
chr22_+_16497670 0.83 ENSDART00000014330
ier5
immediate early response 5
chr3_-_8765165 0.80 ENSDART00000191131
CABZ01058333.1

chr2_-_14798295 0.78 ENSDART00000143430
ENSDART00000145869
si:ch73-366i20.1
si:ch73-366i20.1
chr11_+_13630107 0.76 ENSDART00000172220
si:ch211-1a19.3
si:ch211-1a19.3
chr25_+_21832938 0.74 ENSDART00000148299
ckmt1
creatine kinase, mitochondrial 1
chr23_+_3731375 0.74 ENSDART00000141782
smim29
small integral membrane protein 29
chr16_-_21785261 0.74 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr22_-_15593824 0.72 ENSDART00000123125
tpm4a
tropomyosin 4a
chr21_+_40589770 0.72 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pdk3b
pyruvate dehydrogenase kinase, isozyme 3b
chr14_+_33882973 0.72 ENSDART00000019396
clic2
chloride intracellular channel 2
chr1_-_47071979 0.71 ENSDART00000160817
itsn1
intersectin 1 (SH3 domain protein)
chr4_-_69189894 0.71 ENSDART00000169596
si:ch211-209j12.1
si:ch211-209j12.1
chr14_-_26436760 0.70 ENSDART00000088677
si:dkeyp-110e4.6
si:dkeyp-110e4.6
chr14_-_26436951 0.70 ENSDART00000140173
si:dkeyp-110e4.6
si:dkeyp-110e4.6
chr6_+_33885828 0.70 ENSDART00000179994
gpbp1l1
GC-rich promoter binding protein 1-like 1
chr18_+_14477740 0.70 ENSDART00000146472
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr5_-_19052184 0.70 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr20_-_26532167 0.69 ENSDART00000061914
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr23_+_35714574 0.69 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr1_+_52518176 0.68 ENSDART00000003278
tacr3l
tachykinin receptor 3-like
chr1_-_59139599 0.68 ENSDART00000152233
si:ch1073-110a20.3
si:ch1073-110a20.3
chr4_+_357810 0.68 ENSDART00000163436
ENSDART00000103645
tmem181
transmembrane protein 181
chr6_-_40899618 0.67 ENSDART00000153949
ENSDART00000021969
zgc:172271
zgc:172271
chr9_-_34915351 0.67 ENSDART00000100728
ENSDART00000139608
upf3a
UPF3A, regulator of nonsense mediated mRNA decay
chr4_-_2440175 0.67 ENSDART00000058059
OSBPL8
oxysterol binding protein like 8
chr16_+_49005321 0.64 ENSDART00000160919
CABZ01068499.1

chr5_-_25582721 0.63 ENSDART00000123986
anxa1a
annexin A1a
chr25_+_22643954 0.63 ENSDART00000182843
ENSDART00000121791
ush1c
Usher syndrome 1C
chr14_+_8725216 0.63 ENSDART00000157630
pimr57
Pim proto-oncogene, serine/threonine kinase, related 57
chr4_+_16715267 0.62 ENSDART00000143849
pkp2
plakophilin 2
chr23_+_4324625 0.62 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
ENSDART00000179819
sgk2a
serum/glucocorticoid regulated kinase 2a
chr9_-_27805644 0.61 ENSDART00000192431
si:rp71-45g20.10
si:rp71-45g20.10
chr2_-_49997055 0.60 ENSDART00000140294
si:ch211-106n13.3
si:ch211-106n13.3
chr8_+_44714336 0.60 ENSDART00000145801
elmod3
ELMO/CED-12 domain containing 3
chr5_+_15819651 0.60 ENSDART00000081230
ENSDART00000186969
ENSDART00000134206
hspb8
heat shock protein b8
chr25_+_7423770 0.60 ENSDART00000155458
ubap1la
ubiquitin associated protein 1-like a
chr7_-_29200090 0.60 ENSDART00000173973
herc1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr20_-_26531850 0.58 ENSDART00000183317
ENSDART00000131994
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr11_+_26609110 0.58 ENSDART00000042322
map1lc3a
microtubule-associated protein 1 light chain 3 alpha
chr5_+_54400971 0.56 ENSDART00000169695
bspry
B-box and SPRY domain containing
chr14_+_49382180 0.55 ENSDART00000158329
tnip1
TNFAIP3 interacting protein 1
chr19_-_12078583 0.53 ENSDART00000024193
rnf19a
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr19_-_31402429 0.52 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr3_+_25825043 0.52 ENSDART00000153749
pik3r6b
phosphoinositide-3-kinase, regulatory subunit 6b
chr8_+_3530761 0.51 ENSDART00000081272
gcn1
GCN1 eIF2 alpha kinase activator homolog
chr2_+_42236118 0.51 ENSDART00000114162
ENSDART00000141199
ftr02
finTRIM family, member 2
chr15_-_30832171 0.50 ENSDART00000152414
ENSDART00000152790
msi2b
musashi RNA-binding protein 2b
chr18_-_18849916 0.50 ENSDART00000142422
tgm2l
transglutaminase 2, like
chr21_+_22845317 0.50 ENSDART00000065555
birc2
baculoviral IAP repeat containing 2
chr6_-_442163 0.49 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
grap2b
GRB2-related adaptor protein 2b
chr18_+_50089000 0.49 ENSDART00000058936
scamp5b
secretory carrier membrane protein 5b
chr24_+_39186940 0.48 ENSDART00000155817
spsb3b
splA/ryanodine receptor domain and SOCS box containing 3b
chr16_-_21668082 0.46 ENSDART00000088513
gnl1
guanine nucleotide binding protein-like 1
chr23_+_33718602 0.46 ENSDART00000024695
dazap2
DAZ associated protein 2
chr1_-_33380340 0.46 ENSDART00000181515
cd99
CD99 molecule
chr5_+_38276582 0.45 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr25_-_3549321 0.45 ENSDART00000181214
ENSDART00000160600
hdhd5
haloacid dehalogenase like hydrolase domain containing 5
chr7_+_23577723 0.45 ENSDART00000049885
si:dkey-172j4.3
si:dkey-172j4.3
chr25_-_173165 0.44 ENSDART00000193594
CABZ01114053.1

chr21_+_30502002 0.44 ENSDART00000043727
slc7a3a
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3a
chr20_-_54508650 0.43 ENSDART00000147642
CABZ01118770.1

chr19_+_37118547 0.42 ENSDART00000103163
cx30.9
connexin 30.9
chr16_+_9762261 0.42 ENSDART00000020654
psmd4b
proteasome 26S subunit, non-ATPase 4b
chr5_+_21225017 0.42 ENSDART00000141573
si:dkey-13n15.11
si:dkey-13n15.11
chr4_-_13902188 0.42 ENSDART00000032805
gxylt1b
glucoside xylosyltransferase 1b
chr2_-_41861040 0.41 ENSDART00000045763
keap1a
kelch-like ECH-associated protein 1a
chr12_-_28363111 0.41 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr21_+_5636008 0.41 ENSDART00000158385
shroom3
shroom family member 3
chr21_-_2238277 0.40 ENSDART00000165754
si:dkey-50i6.6
si:dkey-50i6.6
chr14_+_34966598 0.40 ENSDART00000004550
rnf145a
ring finger protein 145a
chr2_+_7849890 0.39 ENSDART00000114241
si:ch211-38m6.6
si:ch211-38m6.6
chr22_+_36547670 0.39 ENSDART00000125991
ENSDART00000186372
armc9
armadillo repeat containing 9
chr9_-_710896 0.39 ENSDART00000180478
ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr20_+_7084154 0.39 ENSDART00000136448
ftr85
finTRIM family, member 85
chr14_-_33613794 0.38 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr19_+_22216778 0.38 ENSDART00000052521
nfatc1
nuclear factor of activated T cells 1
chr21_+_10794914 0.38 ENSDART00000084035
znf532
zinc finger protein 532
chr6_-_41091151 0.38 ENSDART00000154963
ENSDART00000153818
srsf3a
serine/arginine-rich splicing factor 3a
chr24_-_6078222 0.37 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_+_41588170 0.37 ENSDART00000139175
si:dkey-56e3.2
si:dkey-56e3.2
chr11_+_11267829 0.37 ENSDART00000026814
ENSDART00000173346
ENSDART00000151926
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr12_-_36521947 0.37 ENSDART00000152946
unc13d
unc-13 homolog D (C. elegans)
chr3_+_19207176 0.37 ENSDART00000087803
rln3a
relaxin 3a
chr2_+_21486529 0.36 ENSDART00000047468
inhbab
inhibin, beta Ab
chr13_-_11035420 0.36 ENSDART00000108709
cep170aa
centrosomal protein 170Aa
chr7_+_23875269 0.36 ENSDART00000101406
rab39bb
RAB39B, member RAS oncogene family b
chr6_+_13933464 0.35 ENSDART00000109144
ptprnb
protein tyrosine phosphatase, receptor type, Nb
chr23_+_40460333 0.35 ENSDART00000184658
soga3b
SOGA family member 3b
chr4_-_25168458 0.34 ENSDART00000066929
taf3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto
chr8_+_50983551 0.34 ENSDART00000142061
si:dkey-32e23.4
si:dkey-32e23.4
chr19_-_7495006 0.33 ENSDART00000148836
rfx5
regulatory factor X, 5
chr2_-_985417 0.33 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr6_-_25189739 0.33 ENSDART00000181980
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr15_-_37733238 0.33 ENSDART00000115178
si:dkey-42l23.7
si:dkey-42l23.7
chr16_-_28878080 0.33 ENSDART00000149501
si:dkey-239n17.4
si:dkey-239n17.4
chr4_+_47656992 0.32 ENSDART00000161148
znf1040
zinc finger protein 1040
chr10_+_28428222 0.32 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr4_+_5317483 0.32 ENSDART00000150366
si:ch211-214j24.10
si:ch211-214j24.10
chr13_+_6086730 0.31 ENSDART00000049328
fam120b
family with sequence similarity 120B
chr5_+_61556172 0.30 ENSDART00000131937
orai2
ORAI calcium release-activated calcium modulator 2
chr21_+_6328801 0.30 ENSDART00000163577
fnbp1b
formin binding protein 1b
chr4_-_20208166 0.30 ENSDART00000066891
gsap
gamma-secretase activating protein
chr5_-_43959972 0.29 ENSDART00000180517
si:ch211-204c21.1
si:ch211-204c21.1
chr7_+_13418812 0.29 ENSDART00000191905
ENSDART00000091567
dagla
diacylglycerol lipase, alpha
chr25_+_13191615 0.28 ENSDART00000168849
si:ch211-147m6.2
si:ch211-147m6.2
chr11_+_13629528 0.28 ENSDART00000186509
si:ch211-1a19.3
si:ch211-1a19.3
chr7_+_33172066 0.27 ENSDART00000174013
si:ch211-194p6.12
si:ch211-194p6.12
chr25_+_3549401 0.27 ENSDART00000166312
ccdc77
coiled-coil domain containing 77
chr23_+_24272421 0.27 ENSDART00000029974
clcnk
chloride channel K
chr4_+_77971104 0.27 ENSDART00000188609
zgc:113921
zgc:113921
chr19_+_9050852 0.27 ENSDART00000151031
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr2_-_32366287 0.27 ENSDART00000144758
ubtfl
upstream binding transcription factor, like
chr2_-_22927958 0.26 ENSDART00000141621
myo7bb
myosin VIIBb
chr18_+_5137241 0.26 ENSDART00000159601
serpini1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr25_+_21324588 0.25 ENSDART00000151842
lrrn3a
leucine rich repeat neuronal 3a
chr8_-_52871056 0.25 ENSDART00000170179
nr5a1a
nuclear receptor subfamily 5, group A, member 1a
chr8_-_20291922 0.25 ENSDART00000148304
myo1f
myosin IF
chr10_-_300000 0.25 ENSDART00000183273
emsy
EMSY BRCA2-interacting transcriptional repressor
chr7_+_50395856 0.25 ENSDART00000032324
hddc3
HD domain containing 3
chr3_-_10621391 0.25 ENSDART00000058834
map2k4a
mitogen-activated protein kinase kinase 4a
chr15_-_41438821 0.25 ENSDART00000136952
nlrc8
NLR family CARD domain containing 8
chr3_-_32859335 0.24 ENSDART00000158916
si:dkey-16l2.20
si:dkey-16l2.20
chr10_+_1638876 0.24 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
sgsm1b
small G protein signaling modulator 1b
chr17_+_15413412 0.24 ENSDART00000149871
cx40.8
connexin 40.8
chr15_+_2421729 0.23 ENSDART00000082294
ENSDART00000156428
hephl1a
hephaestin-like 1a
chr25_+_13191391 0.23 ENSDART00000109937
si:ch211-147m6.2
si:ch211-147m6.2
chr4_-_28958601 0.23 ENSDART00000111294
zgc:174315
zgc:174315
chr5_-_9073433 0.23 ENSDART00000099891
atp5meb
ATP synthase membrane subunit eb
chr4_+_77933084 0.23 ENSDART00000148728
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr8_+_20950401 0.23 ENSDART00000136484
ENSDART00000131329
ENSDART00000144451
ENSDART00000144929
si:dkeyp-82a1.1
si:dkeyp-82a1.1
chr4_-_19742300 0.23 ENSDART00000066964
ENSDART00000100952
hgfa
hepatocyte growth factor a
chr3_-_61185746 0.22 ENSDART00000028219
pvalb4
parvalbumin 4
chr9_-_21838045 0.22 ENSDART00000147471
acod1
aconitate decarboxylase 1
chr25_-_11026907 0.22 ENSDART00000156846
mespbb
mesoderm posterior bb
chr3_-_34069637 0.22 ENSDART00000151588
ighv9-1
immunoglobulin heavy variable 9-1
chr10_+_466926 0.22 ENSDART00000145220
arvcfa
ARVCF, delta catenin family member a
chr8_+_41038141 0.21 ENSDART00000075620
gpat2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr2_+_30379650 0.21 ENSDART00000129542
crispld1b
cysteine-rich secretory protein LCCL domain containing 1b
chr23_+_37185247 0.21 ENSDART00000146269
vwa5b1
von Willebrand factor A domain containing 5B1
chr1_+_8601935 0.20 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr16_+_20915319 0.20 ENSDART00000079383
hoxa9b
homeobox A9b
chr19_+_42847306 0.20 ENSDART00000135164
pdcd6ip
programmed cell death 6 interacting protein
chr10_-_4316015 0.20 ENSDART00000109916
ENSDART00000180867
grin3a
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr3_-_7436932 0.20 ENSDART00000163501
CR847850.1

chr7_+_53541173 0.20 ENSDART00000159449
gramd2aa
GRAM domain containing 2Aa
chr9_+_41024973 0.20 ENSDART00000014660
ENSDART00000144467
ormdl1
ORMDL sphingolipid biosynthesis regulator 1
chr2_-_3038904 0.19 ENSDART00000186795
guk1a
guanylate kinase 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of fosb+fosl2+si:ch211-153j24.3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.3 0.9 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.3 1.1 GO:0042117 plasma membrane repair(GO:0001778) monocyte activation(GO:0042117)
0.2 1.2 GO:0045124 regulation of bone resorption(GO:0045124)
0.2 1.2 GO:0070254 mucus secretion(GO:0070254)
0.2 2.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.2 1.5 GO:0008343 adult feeding behavior(GO:0008343)
0.2 2.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.2 3.5 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.5 GO:0060546 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 3.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.9 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.6 GO:0045625 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.7 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.6 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.6 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.4 GO:0089718 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 2.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 1.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.7 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 1.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.0 GO:0030800 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.0 0.7 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.6 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.3 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:1903426 regulation of reactive oxygen species biosynthetic process(GO:1903426)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.9 GO:0006826 iron ion transport(GO:0006826)
0.0 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.8 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.2 GO:0008206 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.6 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.3 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 6.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0001843 neural tube closure(GO:0001843)
0.0 0.2 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.7 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.5 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.6 GO:0034620 cellular response to unfolded protein(GO:0034620)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 1.8 GO:0016589 NURF complex(GO:0016589)
0.3 3.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.2 3.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.1 GO:0030315 T-tubule(GO:0030315)
0.1 0.6 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.1 0.4 GO:0016234 inclusion body(GO:0016234)
0.0 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 0.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 8.0 GO:0005929 cilium(GO:0005929)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.3 0.9 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.3 2.8 GO:0004046 aminoacylase activity(GO:0004046)
0.2 1.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 1.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.6 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.9 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.0 GO:0008026 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 0.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.0 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 2.3 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.0 0.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors