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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for fosl2l

Z-value: 0.49

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Transcription factors associated with fosl2l

Gene Symbol Gene ID Gene Info
fosl2l
ENSDARG00000092174 fos-like antigen 2 like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:ch211-59d15.4dr11_v1_chr20_+_9211237_9211237-0.272.8e-01Click!

Activity profile of fosl2l motif

Sorted Z-values of fosl2l motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_32877348 1.10 ENSDART00000018977
ENSDART00000133421
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1
chr24_-_33366188 0.91 ENSDART00000074161
slc4a2b
solute carrier family 4 (anion exchanger), member 2b
chr1_+_46598764 0.78 ENSDART00000053240
cab39l
calcium binding protein 39-like
chr7_-_26262978 0.67 ENSDART00000137769
ap1s1
adaptor-related protein complex 1, sigma 1 subunit
chr16_+_23403602 0.66 ENSDART00000159848
s100w
S100 calcium binding protein W
chr5_+_9037650 0.62 ENSDART00000158226
si:ch211-155m12.1
si:ch211-155m12.1
chr1_+_46598502 0.62 ENSDART00000132861
cab39l
calcium binding protein 39-like
chr8_+_8671229 0.61 ENSDART00000131963
usp11
ubiquitin specific peptidase 11
chr19_+_37120491 0.59 ENSDART00000032341
pef1
penta-EF-hand domain containing 1
chr19_-_7043355 0.57 ENSDART00000104845
tapbp.1
TAP binding protein (tapasin), tandem duplicate 1
chr6_-_33685325 0.57 ENSDART00000181883
mast2
microtubule associated serine/threonine kinase 2
chr7_+_66884570 0.56 ENSDART00000082664
sbf2
SET binding factor 2
chr22_+_17399124 0.51 ENSDART00000145769
rabgap1l
RAB GTPase activating protein 1-like
chr12_-_3077395 0.49 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_+_34549845 0.48 ENSDART00000139317
aif1l
allograft inflammatory factor 1-like
chr20_-_34670236 0.48 ENSDART00000033325
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr2_-_985417 0.46 ENSDART00000140540
si:ch211-241e1.3
si:ch211-241e1.3
chr6_-_59357256 0.46 ENSDART00000074534
fam210b
family with sequence similarity 210, member B
chr20_+_23501535 0.45 ENSDART00000177922
ENSDART00000058532
palld
palladin, cytoskeletal associated protein
chr9_+_33154841 0.44 ENSDART00000132465
dopey2
dopey family member 2
chr24_+_24726956 0.44 ENSDART00000144574
ENSDART00000066628
mtfr1
mitochondrial fission regulator 1
chr22_+_24603930 0.44 ENSDART00000180240
ENSDART00000164256
CU655842.1

chr5_-_49951106 0.44 ENSDART00000135954
fam172a
family with sequence similarity 172, member A
chr21_+_13245302 0.44 ENSDART00000189498
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr9_+_22929675 0.44 ENSDART00000061299
tsn
translin
chr19_-_7070691 0.43 ENSDART00000168755
tapbp.2
TAP binding protein (tapasin), tandem duplicate 2
chr5_-_13076779 0.42 ENSDART00000192826
ypel1
yippee-like 1
chr23_-_24226533 0.42 ENSDART00000109134
plekhm2
pleckstrin homology domain containing, family M (with RUN domain) member 2
chr18_+_15841449 0.41 ENSDART00000141800
ENSDART00000091349
eea1
early endosome antigen 1
chr7_-_7764287 0.41 ENSDART00000173021
ENSDART00000113131
intu
inturned planar cell polarity protein
chr17_+_51743908 0.41 ENSDART00000149039
ENSDART00000148869
odc1
ornithine decarboxylase 1
chr12_-_17147473 0.40 ENSDART00000106035
stambpl1
STAM binding protein-like 1
chr9_+_33158191 0.39 ENSDART00000180786
dopey2
dopey family member 2
chr20_+_28364742 0.39 ENSDART00000103355
rhov
ras homolog family member V
chr15_+_17343319 0.39 ENSDART00000018461
vmp1
vacuole membrane protein 1
chr22_+_23359369 0.39 ENSDART00000170886
dennd1b
DENN/MADD domain containing 1B
chr21_+_43199237 0.39 ENSDART00000151748
aff4
AF4/FMR2 family, member 4
chr21_-_20945658 0.38 ENSDART00000079701
rnf180
ring finger protein 180
chr16_+_13818743 0.38 ENSDART00000090191
flcn
folliculin
chr4_+_20051478 0.38 ENSDART00000143642
lamtor4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr4_-_1801519 0.38 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr23_+_28378543 0.38 ENSDART00000145327
zgc:153867
zgc:153867
chr5_+_51227147 0.37 ENSDART00000083340
ubac1
UBA domain containing 1
chr17_+_51744450 0.37 ENSDART00000190955
ENSDART00000149807
odc1
ornithine decarboxylase 1
chr4_+_25181572 0.36 ENSDART00000078529
ENSDART00000136643
kin
Kin17 DNA and RNA binding protein
chr12_-_5455936 0.35 ENSDART00000109305
tbc1d12b
TBC1 domain family, member 12b
chr16_+_13818500 0.35 ENSDART00000135245
flcn
folliculin
chr19_-_5805923 0.34 ENSDART00000134340
si:ch211-264f5.8
si:ch211-264f5.8
chr12_-_35787801 0.33 ENSDART00000171682
aatkb
apoptosis-associated tyrosine kinase b
chr9_+_28140089 0.33 ENSDART00000046880
plekhm3
pleckstrin homology domain containing, family M, member 3
chr2_+_37838259 0.33 ENSDART00000136796
parp2
poly (ADP-ribose) polymerase 2
chr22_+_26600834 0.32 ENSDART00000157411
adcy9
adenylate cyclase 9
chr10_+_16225117 0.32 ENSDART00000169885
slc12a2
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr25_+_3549401 0.32 ENSDART00000166312
ccdc77
coiled-coil domain containing 77
chr4_+_5317483 0.31 ENSDART00000150366
si:ch211-214j24.10
si:ch211-214j24.10
chr6_+_51713076 0.30 ENSDART00000146281
ripor3
RIPOR family member 3
chr17_+_32623931 0.30 ENSDART00000144217
ctsba
cathepsin Ba
chr7_+_50395856 0.30 ENSDART00000032324
hddc3
HD domain containing 3
chr18_-_37355666 0.30 ENSDART00000098914
yap1
Yes-associated protein 1
chr2_+_25378457 0.29 ENSDART00000089108
fndc3ba
fibronectin type III domain containing 3Ba
chr6_+_49901465 0.29 ENSDART00000023515
chmp4ba
charged multivesicular body protein 4Ba
chr11_-_18601955 0.29 ENSDART00000180565
zmynd8
zinc finger, MYND-type containing 8
chr3_+_19245804 0.29 ENSDART00000134514
smarca4a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr9_+_41024973 0.29 ENSDART00000014660
ENSDART00000144467
ormdl1
ORMDL sphingolipid biosynthesis regulator 1
chr7_-_7398350 0.28 ENSDART00000012637
zgc:101810
zgc:101810
chr6_+_54711306 0.28 ENSDART00000074605
pkp1b
plakophilin 1b
chr19_-_43750389 0.27 ENSDART00000147328
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr3_+_19687217 0.27 ENSDART00000141937
tlk2
tousled-like kinase 2
chr3_-_39190317 0.27 ENSDART00000013167
retsat
retinol saturase (all-trans-retinol 13,14-reductase)
chr4_+_1722899 0.27 ENSDART00000021139
fgfr1op2
FGFR1 oncogene partner 2
chr15_+_24704798 0.27 ENSDART00000192470
LRRC75A
si:dkey-151p21.7
chr3_-_32362872 0.26 ENSDART00000035545
ENSDART00000012630
prmt1
protein arginine methyltransferase 1
chr3_-_21062706 0.26 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
fam57ba
family with sequence similarity 57, member Ba
chr7_+_34549198 0.25 ENSDART00000173784
fhod1
formin homology 2 domain containing 1
chr11_-_11965033 0.25 ENSDART00000193683
abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr12_-_27212596 0.25 ENSDART00000153101
psme3
proteasome activator subunit 3
chr5_-_42123794 0.25 ENSDART00000051135
emc6
ER membrane protein complex subunit 6
chr8_+_50190742 0.25 ENSDART00000099863
slc25a37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr3_-_24205339 0.24 ENSDART00000157135
si:dkey-110g7.8
si:dkey-110g7.8
chr21_+_6290566 0.24 ENSDART00000161647
fnbp1b
formin binding protein 1b
chr21_-_14692119 0.24 ENSDART00000123047
ehmt1b
euchromatic histone-lysine N-methyltransferase 1b
chr15_+_40188076 0.24 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr24_-_31090948 0.24 ENSDART00000176799
hccsb
holocytochrome c synthase b
chr15_+_20352123 0.23 ENSDART00000011030
ENSDART00000163532
ENSDART00000169537
ENSDART00000161047
il15l
interleukin 15, like
chr7_+_34549377 0.23 ENSDART00000191814
fhod1
formin homology 2 domain containing 1
chr23_-_14990865 0.23 ENSDART00000147799
ndrg3b
ndrg family member 3b
chr23_-_7797207 0.22 ENSDART00000181611
myt1b
myelin transcription factor 1b
chr25_+_18583877 0.22 ENSDART00000148741
met
MET proto-oncogene, receptor tyrosine kinase
chr19_+_48359259 0.22 ENSDART00000167353
sgo1
shugoshin 1
chr23_-_36003441 0.22 ENSDART00000164699
calcoco1a
calcium binding and coiled-coil domain 1a
chr1_+_41690402 0.21 ENSDART00000177298
fbxo41
F-box protein 41
chr13_+_6188759 0.21 ENSDART00000161062
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr8_-_11170114 0.21 ENSDART00000133532
si:ch211-204d2.4
si:ch211-204d2.4
chr11_+_45153104 0.21 ENSDART00000159204
ENSDART00000177585
tk1
thymidine kinase 1, soluble
chr18_+_618005 0.21 ENSDART00000189667
prtga
protogenin homolog a (Gallus gallus)
chr15_+_2559875 0.21 ENSDART00000178505
SH2B2
SH2B adaptor protein 2
chr8_-_18516385 0.21 ENSDART00000149446
si:dkey-30h22.11
si:dkey-30h22.11
chr25_+_13498188 0.20 ENSDART00000015710
snrkb
SNF related kinase b
chr21_+_6328801 0.20 ENSDART00000163577
fnbp1b
formin binding protein 1b
chr8_+_54274355 0.19 ENSDART00000067639
TMCC1 (1 of many)
transmembrane and coiled-coil domain family 1
chr23_-_7799184 0.19 ENSDART00000190946
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr12_+_32292564 0.19 ENSDART00000152945
ANKFN1
si:ch211-277e21.2
chr18_-_41160975 0.19 ENSDART00000187517
CABZ01005876.1

chr25_+_8407892 0.19 ENSDART00000153536
muc5.2
mucin 5.2
chr23_-_36003282 0.19 ENSDART00000103150
calcoco1a
calcium binding and coiled-coil domain 1a
chr23_+_19759128 0.19 ENSDART00000135820
flna
filamin A, alpha (actin binding protein 280)
chr25_-_31907590 0.18 ENSDART00000149707
ENSDART00000149471
eif3ja
eukaryotic translation initiation factor 3, subunit Ja
chr5_-_20678300 0.18 ENSDART00000088639
wscd2
WSC domain containing 2
chr24_+_19415124 0.18 ENSDART00000186931
sulf1
sulfatase 1
chr17_+_43946269 0.18 ENSDART00000017376
ktn1
kinectin 1
chr23_-_437467 0.18 ENSDART00000192106
tspan2b
tetraspanin 2b
chr15_+_29709382 0.18 ENSDART00000099956
nrip1a
nuclear receptor interacting protein 1a
chr13_+_6189203 0.17 ENSDART00000109665
ppm1g
protein phosphatase, Mg2+/Mn2+ dependent, 1G
chr4_-_4535189 0.17 ENSDART00000057519
zgc:194209
zgc:194209
chr14_-_22100118 0.17 ENSDART00000157547
ssrp1a
structure specific recognition protein 1a
chr3_+_24708685 0.17 ENSDART00000153507
mkl1a
megakaryoblastic leukemia (translocation) 1a
chr25_+_10410620 0.17 ENSDART00000151886
ehf
ets homologous factor
chr7_-_40145097 0.17 ENSDART00000173634
wdr60
WD repeat domain 60
chr19_+_49721 0.17 ENSDART00000160489
col14a1b
collagen, type XIV, alpha 1b
chr5_-_23464970 0.17 ENSDART00000141028
si:dkeyp-20g2.1
si:dkeyp-20g2.1
chr25_-_6432463 0.17 ENSDART00000110389
ptpn9a
protein tyrosine phosphatase, non-receptor type 9, a
chr4_-_789645 0.17 ENSDART00000164441
mapre3b
microtubule-associated protein, RP/EB family, member 3b
chr17_+_24597001 0.16 ENSDART00000191834
rlf
rearranged L-myc fusion
chr5_+_24059598 0.16 ENSDART00000051547
gabarapa
GABA(A) receptor-associated protein a
chr19_+_15441022 0.16 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr6_-_60079551 0.16 ENSDART00000154753
pmepa1
prostate transmembrane protein, androgen induced 1
chr3_-_30248277 0.16 ENSDART00000133516
ENSDART00000077029
emc10
ER membrane protein complex subunit 10
chr7_+_67381912 0.16 ENSDART00000167564
nfat5b
nuclear factor of activated T cells 5b
chr9_-_12493628 0.16 ENSDART00000180832
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr10_+_11260170 0.16 ENSDART00000155742
hsdl2
hydroxysteroid dehydrogenase like 2
chr23_-_1017428 0.16 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr9_+_46745348 0.15 ENSDART00000025256
igfbp2b
insulin-like growth factor binding protein 2b
chr23_-_31693309 0.15 ENSDART00000146327
sgk1
serum/glucocorticoid regulated kinase 1
chr6_-_25189739 0.15 ENSDART00000181980
lrrc8db
leucine rich repeat containing 8 VRAC subunit Db
chr13_-_33134611 0.15 ENSDART00000026280
plek2
pleckstrin 2
chr24_+_80653 0.15 ENSDART00000158473
ENSDART00000129135
reck
reversion-inducing-cysteine-rich protein with kazal motifs
chr5_+_19320554 0.15 ENSDART00000165119
rusc2
RUN and SH3 domain containing 2
chr13_+_19283936 0.15 ENSDART00000111462
eif3s10
eukaryotic translation initiation factor 3, subunit 10 (theta)
chr10_-_105100 0.15 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr25_+_32496723 0.15 ENSDART00000087978
ctdspl2a
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a
chr19_-_43757568 0.14 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr7_-_40144686 0.14 ENSDART00000109166
wdr60
WD repeat domain 60
chr6_+_18367388 0.14 ENSDART00000163394
dgke
diacylglycerol kinase, epsilon
chr4_+_9400012 0.14 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr21_-_30254185 0.14 ENSDART00000101054
dnajc18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr8_-_22288004 0.14 ENSDART00000100042
si:ch211-147a11.3
si:ch211-147a11.3
chr12_+_1286642 0.14 ENSDART00000157467
pemt
phosphatidylethanolamine N-methyltransferase
chr23_+_24989387 0.14 ENSDART00000172299
ENSDART00000145307
arhgap4a
Rho GTPase activating protein 4a
chr7_+_7019911 0.14 ENSDART00000172421
rbm14b
RNA binding motif protein 14b
chr19_-_7420867 0.14 ENSDART00000081741
rab25a
RAB25, member RAS oncogene family a
chr8_-_22288258 0.13 ENSDART00000140978
ENSDART00000100046
si:ch211-147a11.3
si:ch211-147a11.3
chr10_-_13239367 0.13 ENSDART00000001253
si:busm1-57f23.1
si:busm1-57f23.1
chr5_+_61556172 0.13 ENSDART00000131937
orai2
ORAI calcium release-activated calcium modulator 2
chr23_+_33718602 0.13 ENSDART00000024695
dazap2
DAZ associated protein 2
chr21_+_17301790 0.13 ENSDART00000145057
tsc1b
TSC complex subunit 1b
chr8_+_10835456 0.12 ENSDART00000151388
mapk13
mitogen-activated protein kinase 13
chr23_+_30967686 0.12 ENSDART00000144485
si:ch211-197l9.2
si:ch211-197l9.2
chr4_-_4261673 0.12 ENSDART00000150694
cd9b
CD9 molecule b
chr20_-_21994901 0.12 ENSDART00000004984
daam1b
dishevelled associated activator of morphogenesis 1b
chr7_-_44704910 0.12 ENSDART00000037850
dync1li2
dynein, cytoplasmic 1, light intermediate chain 2
chr11_+_11267829 0.12 ENSDART00000026814
ENSDART00000173346
ENSDART00000151926
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr23_-_4704938 0.12 ENSDART00000067293
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr22_+_5574952 0.11 ENSDART00000171774
zgc:171566
zgc:171566
chr2_-_39675829 0.11 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr2_+_47944967 0.11 ENSDART00000135584
ftr19
finTRIM family, member 19
chr7_+_38680034 0.11 ENSDART00000171691
ENSDART00000007913
psmc3
proteasome 26S subunit, ATPase 3
chr3_+_43955864 0.10 ENSDART00000168267
BX571715.1

chr22_-_38543630 0.10 ENSDART00000172029
si:ch211-126j24.1
si:ch211-126j24.1
chr7_-_71456117 0.10 ENSDART00000042492
sepsecs
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr22_+_17828267 0.10 ENSDART00000136016
hapln4
hyaluronan and proteoglycan link protein 4
chr11_-_27821 0.10 ENSDART00000158769
ENSDART00000172970
ENSDART00000173118
ENSDART00000168674
ENSDART00000163545
ENSDART00000173411
ENSDART00000172132
sp1
sp1 transcription factor
chr15_-_43978141 0.10 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr9_+_38481780 0.09 ENSDART00000087241
lss
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr14_+_23184517 0.09 ENSDART00000181410
enox2
ecto-NOX disulfide-thiol exchanger 2
chr23_-_1017605 0.09 ENSDART00000138290
cdh26.1
cadherin 26, tandem duplicate 1
chr2_+_47945359 0.09 ENSDART00000098054
ftr19
finTRIM family, member 19
chr14_-_16807206 0.09 ENSDART00000157957
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr23_+_25292147 0.08 ENSDART00000131486
pa2g4b
proliferation-associated 2G4, b
chr20_-_47347962 0.08 ENSDART00000080863
dtnba
dystrobrevin, beta a
chr18_-_13360106 0.08 ENSDART00000091512
cmip
c-Maf inducing protein
chr20_-_47348116 0.08 ENSDART00000162087
ENSDART00000160769
ENSDART00000164484
dtnba
dystrobrevin, beta a
chr11_-_14102131 0.08 ENSDART00000085158
ENSDART00000191962
tmem259
transmembrane protein 259
chr9_-_9282519 0.08 ENSDART00000146821
si:ch211-214p13.3
si:ch211-214p13.3
chr11_+_11267493 0.08 ENSDART00000148425
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr20_+_37661229 0.07 ENSDART00000138539
aig1
androgen-induced 1 (H. sapiens)
chr2_+_27932781 0.07 ENSDART00000019555
mc4r
melanocortin 4 receptor
chr23_-_4705110 0.07 ENSDART00000144536
ENSDART00000129050
ENSDART00000136399
cnbpa
CCHC-type zinc finger, nucleic acid binding protein a
chr2_-_24407933 0.07 ENSDART00000088584
si:dkey-208k22.6
si:dkey-208k22.6
chr17_-_45150763 0.07 ENSDART00000155043
ENSDART00000156786
ENSDART00000191147
tmed8
transmembrane p24 trafficking protein 8
chr15_+_42235449 0.07 ENSDART00000114801
ENSDART00000182053
SGPP2
sphingosine-1-phosphate phosphatase 2
chr11_-_45152702 0.07 ENSDART00000168066
afmid
arylformamidase
chr17_+_28624321 0.07 ENSDART00000122260
heatr5a
HEAT repeat containing 5a
chr6_-_41091151 0.07 ENSDART00000154963
ENSDART00000153818
srsf3a
serine/arginine-rich splicing factor 3a
chr10_-_44482911 0.07 ENSDART00000085556
hip1ra
huntingtin interacting protein 1 related a
chr9_-_47654204 0.07 ENSDART00000015159
tns1b
tensin 1b
chr16_-_31598771 0.06 ENSDART00000016386
tg
thyroglobulin
chr8_+_29749017 0.06 ENSDART00000185144
mapk4
mitogen-activated protein kinase 4
chr9_+_38962398 0.06 ENSDART00000134294
map2
microtubule-associated protein 2
chr16_+_48714048 0.06 ENSDART00000148709
ENSDART00000150121
brd2b
bromodomain containing 2b
chr4_+_77661056 0.06 ENSDART00000152953
si:dkey-61p9.7
si:dkey-61p9.7

Network of associatons between targets according to the STRING database.

First level regulatory network of fosl2l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.6 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.7 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.4 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.8 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.4 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.2 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.6 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.4 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.3 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.4 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 0.2 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.6 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.0 0.5 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.3 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.4 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.0 0.4 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.5 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.3 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.1 GO:0048521 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:1901296 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0007164 establishment of planar polarity(GO:0001736) establishment of tissue polarity(GO:0007164)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 1.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.4 GO:0035197 siRNA binding(GO:0035197)
0.1 0.8 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 0.4 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.2 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.0 0.4 GO:0032977 membrane insertase activity(GO:0032977)
0.0 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.3 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.3 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism