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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxa3

Z-value: 0.51

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Transcription factors associated with foxa3

Gene Symbol Gene ID Gene Info
foxa3
ENSDARG00000012788 forkhead box A3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxa3dr11_v1_chr18_-_46354269_463542690.799.7e-05Click!

Activity profile of foxa3 motif

Sorted Z-values of foxa3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_52411530 1.78 ENSDART00000163684
nme8
NME/NM23 family member 8
chr16_+_23978978 1.63 ENSDART00000058964
ENSDART00000135084
apoa2
apolipoprotein A-II
chr6_-_40352215 1.51 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr18_+_7456888 1.18 ENSDART00000081468
terb1
telomere repeat binding bouquet formation protein 1
chr12_-_2993095 1.16 ENSDART00000152316
si:dkey-202c14.3
si:dkey-202c14.3
chr1_-_54622227 1.16 ENSDART00000049010
tekt4
tektin 4
chr3_-_43770876 1.14 ENSDART00000160162
zgc:92162
zgc:92162
chr4_-_9722568 1.13 ENSDART00000067190
tspan9b
tetraspanin 9b
chr1_-_10806625 1.11 ENSDART00000139749
si:ch73-222h13.1
si:ch73-222h13.1
chr14_-_8724290 1.10 ENSDART00000161171
pimr56
Pim proto-oncogene, serine/threonine kinase, related 56
chr23_+_42813415 1.08 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr16_-_54455573 1.03 ENSDART00000075275
pklr
pyruvate kinase L/R
chr12_+_26467847 1.03 ENSDART00000022495
ndel1a
nudE neurodevelopment protein 1-like 1a
chr20_-_43462190 1.00 ENSDART00000100697
pimr133
Pim proto-oncogene, serine/threonine kinase, related 133
chr20_-_1383916 0.92 ENSDART00000152373
scara5
scavenger receptor class A, member 5 (putative)
chr12_-_23129453 0.89 ENSDART00000077453
armc4
armadillo repeat containing 4
chr4_-_12795030 0.85 ENSDART00000150427
b2m
beta-2-microglobulin
chr8_+_25902170 0.82 ENSDART00000193130
rhoab
ras homolog gene family, member Ab
chr7_+_38395197 0.82 ENSDART00000138669
cep89
centrosomal protein 89
chr21_-_21324828 0.81 ENSDART00000136033
si:ch211-191j22.7
si:ch211-191j22.7
chr9_+_44431174 0.78 ENSDART00000149726
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr18_+_20566817 0.78 ENSDART00000100716
bida
BH3 interacting domain death agonist
chr4_-_13921185 0.78 ENSDART00000143202
ENSDART00000080334
yaf2
YY1 associated factor 2
chr8_+_24747865 0.76 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr7_-_33023404 0.76 ENSDART00000052383
cd81a
CD81 molecule a
chr14_-_36799280 0.76 ENSDART00000168615
rnf130
ring finger protein 130
chr14_-_25040359 0.76 ENSDART00000162556
TMEM216
si:rp71-1d10.5
chr14_-_17576391 0.75 ENSDART00000161355
ENSDART00000168959
rnf4
ring finger protein 4
chr7_-_58729894 0.73 ENSDART00000149347
chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr14_-_24397718 0.73 ENSDART00000110164
si:ch211-163m17.4
si:ch211-163m17.4
chr1_-_45752010 0.72 ENSDART00000101410
si:ch211-214c7.5
si:ch211-214c7.5
chr20_+_52546186 0.72 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr3_+_24986145 0.70 ENSDART00000055428
cbx7a
chromobox homolog 7a
chr20_-_14925281 0.70 ENSDART00000152641
dnm3a
dynamin 3a
chr4_-_12795436 0.68 ENSDART00000131026
ENSDART00000075127
b2m
beta-2-microglobulin
chr11_+_35364445 0.67 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr21_-_17296789 0.67 ENSDART00000192180
gfi1b
growth factor independent 1B transcription repressor
chr15_+_36941490 0.67 ENSDART00000172664
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr4_-_149334 0.66 ENSDART00000163280
tbk1
TANK-binding kinase 1
chr6_+_24817852 0.66 ENSDART00000165609
barhl2
BarH-like homeobox 2
chr25_-_13188214 0.65 ENSDART00000187298
si:ch211-147m6.1
si:ch211-147m6.1
chr1_+_26071869 0.65 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr5_-_16351306 0.64 ENSDART00000168643
CABZ01088700.1

chr4_+_12358822 0.64 ENSDART00000172557
ENSDART00000150627
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr3_-_45298487 0.63 ENSDART00000102245
pdpk1a
3-phosphoinositide dependent protein kinase 1a
chr16_+_23961276 0.63 ENSDART00000192754
apoeb
apolipoprotein Eb
chr14_-_4120636 0.63 ENSDART00000059230
irf2
interferon regulatory factor 2
chr5_+_49744713 0.61 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr20_-_29474859 0.61 ENSDART00000152906
ENSDART00000045249
scg5
secretogranin V
chr1_-_45752261 0.61 ENSDART00000141756
si:ch211-214c7.5
si:ch211-214c7.5
chr20_-_29475172 0.61 ENSDART00000183164
scg5
secretogranin V
chr1_+_38362412 0.60 ENSDART00000075086
cep44
centrosomal protein 44
chr16_-_21785261 0.59 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr5_-_32882162 0.59 ENSDART00000085769
lrsam1
leucine rich repeat and sterile alpha motif containing 1
chr4_+_14926948 0.59 ENSDART00000019647
psmc2
proteasome 26S subunit, ATPase 2
chr15_+_46386261 0.58 ENSDART00000191793
igsf11
immunoglobulin superfamily member 11
chr22_-_10110959 0.58 ENSDART00000031005
ENSDART00000147580
gls2b
glutaminase 2b (liver, mitochondrial)
chr25_+_19149241 0.58 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr7_+_52766211 0.57 ENSDART00000186191
ppip5k1a
diphosphoinositol pentakisphosphate kinase 1a
chr16_-_50203058 0.56 ENSDART00000154570
vsig10l
V-set and immunoglobulin domain containing 10 like
chr11_-_30634286 0.56 ENSDART00000191019
zgc:153665
zgc:153665
chr19_-_47526737 0.55 ENSDART00000186636
scg5
secretogranin V
chr16_-_41131578 0.55 ENSDART00000102649
ENSDART00000145956
ptpn23a
protein tyrosine phosphatase, non-receptor type 23, a
chr1_+_49668423 0.54 ENSDART00000150880
tsga10
testis specific, 10
chr5_-_28029558 0.54 ENSDART00000078649
abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr5_+_26913120 0.54 ENSDART00000126609
tbx3b
T-box 3b
chr6_+_3934738 0.53 ENSDART00000159673
dync1i2b
dynein, cytoplasmic 1, intermediate chain 2b
chr15_-_34558579 0.53 ENSDART00000140882
ispd
isoprenoid synthase domain containing
chr8_+_17184602 0.52 ENSDART00000050228
ENSDART00000140531
dimt1l
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr2_+_5563077 0.52 ENSDART00000111220
mb21d2
Mab-21 domain containing 2
chr19_-_28789404 0.51 ENSDART00000191453
ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr22_-_24285432 0.51 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr3_+_29941777 0.51 ENSDART00000113889
ifi35
interferon-induced protein 35
chr11_+_2416064 0.49 ENSDART00000067117
ube2v1
ubiquitin-conjugating enzyme E2 variant 1
chr12_+_1455147 0.49 ENSDART00000018752
cops3
COP9 signalosome subunit 3
chr2_+_10134345 0.49 ENSDART00000100725
ahsg2
alpha-2-HS-glycoprotein 2
chr25_+_14087045 0.48 ENSDART00000155770
actc1c
actin, alpha, cardiac muscle 1c
chr1_+_2190714 0.48 ENSDART00000132126
mbnl2
muscleblind-like splicing regulator 2
chr3_+_52442102 0.47 ENSDART00000155455
si:ch211-191c10.1
si:ch211-191c10.1
chr21_+_30549512 0.47 ENSDART00000132831
rab38c
RAB38c, member of RAS oncogene family
chr7_-_27033080 0.47 ENSDART00000173516
nucb2a
nucleobindin 2a
chr23_+_36653376 0.45 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr13_-_47403154 0.44 ENSDART00000114318
bcl2l11
BCL2 like 11
chr2_+_16160906 0.44 ENSDART00000135783
selenoj
selenoprotein J
chr8_-_14184423 0.43 ENSDART00000063817
ndufb11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11
chr3_-_41292275 0.42 ENSDART00000144088
sdk1a
sidekick cell adhesion molecule 1a
chr4_+_1600034 0.42 ENSDART00000146779
slc38a2
solute carrier family 38, member 2
chr16_-_34477805 0.42 ENSDART00000136546
serinc2l
serine incorporator 2, like
chr22_+_31821815 0.41 ENSDART00000159825
dock3
dedicator of cytokinesis 3
chr4_-_6373735 0.41 ENSDART00000140100
MDFIC
si:ch73-156e19.1
chr17_+_6079881 0.41 ENSDART00000033947
chrna2a
cholinergic receptor, nicotinic, alpha 2a (neuronal)
chr1_+_25801648 0.41 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr5_+_34622320 0.41 ENSDART00000141338
enc1
ectodermal-neural cortex 1
chr24_+_25259154 0.40 ENSDART00000171125
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr24_-_26369185 0.40 ENSDART00000080039
lrrc31
leucine rich repeat containing 31
chr11_-_12705608 0.40 ENSDART00000158937
ENSDART00000114391
zgc:174353
zgc:174353
chr19_-_47527093 0.40 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
scg5
secretogranin V
chr5_+_36513605 0.39 ENSDART00000013590
wnt11
wingless-type MMTV integration site family, member 11
chr3_+_13559199 0.39 ENSDART00000166547
si:ch73-106n3.1
si:ch73-106n3.1
chr20_+_51104367 0.38 ENSDART00000073981
eif2s1b
eukaryotic translation initiation factor 2, subunit 1 alpha b
chr24_-_31306724 0.38 ENSDART00000165399
acp5b
acid phosphatase 5b, tartrate resistant
chr23_-_44848961 0.38 ENSDART00000136839
wu:fb72h05
wu:fb72h05
chr3_+_32492467 0.38 ENSDART00000151329
trpm4a
transient receptor potential cation channel, subfamily M, member 4a
chr20_+_6142433 0.38 ENSDART00000054084
ENSDART00000136986
ttr
transthyretin (prealbumin, amyloidosis type I)
chr9_-_456541 0.37 ENSDART00000159596
zgc:91849
zgc:91849
chr1_-_44940830 0.37 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
tmem176
transmembrane protein 176
chr13_-_36439061 0.36 ENSDART00000084867
dcaf5
ddb1 and cul4 associated factor 5
chr18_-_16795262 0.36 ENSDART00000048722
ampd3b
adenosine monophosphate deaminase 3b
chr8_+_26818446 0.35 ENSDART00000134987
ENSDART00000138835
si:ch211-156j16.1
si:ch211-156j16.1
chr4_-_18436899 0.35 ENSDART00000141671
socs2
suppressor of cytokine signaling 2
chr4_-_64703 0.35 ENSDART00000167851
CU856344.1

chr7_-_26844064 0.34 ENSDART00000162241
si:ch211-107p11.3
si:ch211-107p11.3
chr3_+_5575313 0.34 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
si:ch211-106h11.3
chr17_+_51262556 0.34 ENSDART00000186748
ENSDART00000181606
ENSDART00000063738
ENSDART00000189066
eipr1
EARP complex and GARP complex interacting protein 1
chr4_-_14926637 0.34 ENSDART00000110199
prdm4
PR domain containing 4
chr21_+_17768174 0.33 ENSDART00000141380
rxraa
retinoid X receptor, alpha a
chr21_-_20840714 0.32 ENSDART00000144861
ENSDART00000139430
c6
complement component 6
chr22_+_6905210 0.32 ENSDART00000167530
CABZ01065328.2

chr21_-_22951604 0.32 ENSDART00000083449
ENSDART00000180129
dub
duboraya
chr19_+_19600297 0.32 ENSDART00000160134
ENSDART00000183493
hibadha
3-hydroxyisobutyrate dehydrogenase a
chr3_-_41292569 0.32 ENSDART00000111856
sdk1a
sidekick cell adhesion molecule 1a
chr25_-_31423493 0.32 ENSDART00000027661
myod1
myogenic differentiation 1
chr18_+_17611627 0.31 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr5_-_66160415 0.31 ENSDART00000073895
mboat4
membrane bound O-acyltransferase domain containing 4
chr15_+_15390882 0.31 ENSDART00000062024
ca4b
carbonic anhydrase IV b
chr21_-_25573064 0.30 ENSDART00000134310
CR388166.1

chr6_-_8736766 0.30 ENSDART00000143956
cavin2b
caveolae associated protein 2b
chr24_+_23716918 0.29 ENSDART00000080332
cops5
COP9 signalosome subunit 5
chr8_+_48484455 0.29 ENSDART00000122737
PRDM16
si:ch211-263k4.2
chr3_-_6719232 0.28 ENSDART00000154294
atg4db
autophagy related 4D, cysteine peptidase b
chr17_+_8324345 0.28 ENSDART00000172443
cdc42bpaa
CDC42 binding protein kinase alpha (DMPK-like) a
chr4_-_1824836 0.28 ENSDART00000111858
mrpl42
mitochondrial ribosomal protein L42
chr22_-_21176269 0.27 ENSDART00000112839
rex1bd
required for excision 1-B domain containing
chr10_+_19017146 0.27 ENSDART00000038674
tmem230a
transmembrane protein 230a
chr17_-_53439866 0.27 ENSDART00000154826
mycbp
c-myc binding protein
chr15_-_28247583 0.26 ENSDART00000112967
rilp
Rab interacting lysosomal protein
chr16_+_11724230 0.26 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr8_+_8012570 0.26 ENSDART00000183429
si:ch211-169p10.1
si:ch211-169p10.1
chr24_-_26485098 0.26 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eif5a
eukaryotic translation initiation factor 5A
chr12_-_32066469 0.26 ENSDART00000140685
ENSDART00000062185
rab40b
RAB40B, member RAS oncogene family
chr16_+_43152727 0.26 ENSDART00000125590
ENSDART00000154493
adam22
ADAM metallopeptidase domain 22
chr10_-_25069155 0.25 ENSDART00000078226
ENSDART00000181941
mtnr1bb
melatonin receptor 1Bb
chr11_-_36350876 0.25 ENSDART00000146495
ENSDART00000020655
psma5
proteasome subunit alpha 5
chr3_+_12484008 0.25 ENSDART00000182229
vasnb
vasorin b
chr20_+_38525567 0.25 ENSDART00000147787
znf512
zinc finger protein 512
chr15_+_29123031 0.25 ENSDART00000133988
ENSDART00000060030
zgc:101731
zgc:101731
chr8_+_39795918 0.25 ENSDART00000143413
si:ch211-170d8.2
si:ch211-170d8.2
chr11_-_36350421 0.25 ENSDART00000141477
psma5
proteasome subunit alpha 5
chr2_+_38161318 0.25 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr20_+_46492175 0.24 ENSDART00000060695
zc3h14
zinc finger CCCH-type containing 14
chr11_+_7528599 0.24 ENSDART00000171813
adgrl2a
adhesion G protein-coupled receptor L2a
chr21_-_39081107 0.24 ENSDART00000075935
vtnb
vitronectin b
chr7_-_18545515 0.23 ENSDART00000040534
rgs12a
regulator of G protein signaling 12a
chr24_+_11381400 0.23 ENSDART00000058703
ackr4b
atypical chemokine receptor 4b
chr19_-_6134802 0.23 ENSDART00000140051
cica
capicua transcriptional repressor a
chr9_+_13714379 0.23 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr23_+_24600494 0.23 ENSDART00000184854
nckap5l
NCK-associated protein 5-like
chr2_-_11258547 0.23 ENSDART00000165803
ENSDART00000193817
slc44a5a
solute carrier family 44, member 5a
chr8_+_12930216 0.23 ENSDART00000115405
KIF2A
zgc:103670
chr9_+_44430974 0.23 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr9_-_34396264 0.23 ENSDART00000045754
grtp1b
growth hormone regulated TBC protein 1b
chr11_-_31172276 0.22 ENSDART00000171520
si:dkey-238i5.3
si:dkey-238i5.3
chr5_+_32345187 0.22 ENSDART00000147132
c9
complement component 9
chr25_+_4812685 0.22 ENSDART00000193103
myo5c
myosin VC
chr6_+_41446541 0.22 ENSDART00000029553
ENSDART00000128756
ENSDART00000144864
rsg1
REM2 and RAB-like small GTPase 1
chr9_-_21912227 0.22 ENSDART00000145576
lmo7a
LIM domain 7a
chr23_+_32044410 0.22 ENSDART00000048628
mylk2
myosin light chain kinase 2
chr20_+_38620681 0.22 ENSDART00000045850
si:ch211-243j20.2
si:ch211-243j20.2
chr15_+_36187434 0.22 ENSDART00000181536
ENSDART00000099501
ENSDART00000154432
masp1
mannan-binding lectin serine peptidase 1
chr15_+_24644016 0.21 ENSDART00000043292
smtnl
smoothelin, like
chr20_+_54274431 0.21 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr5_-_24000211 0.21 ENSDART00000188865
map7d2a
MAP7 domain containing 2a
chr22_+_7497319 0.21 ENSDART00000034564
CELA1 (1 of many)
zgc:92511
chr4_-_16334362 0.21 ENSDART00000101461
epyc
epiphycan
chr20_-_39273505 0.20 ENSDART00000153114
clu
clusterin
chr17_+_43843536 0.20 ENSDART00000164097
FO704777.1

chr9_-_2573121 0.20 ENSDART00000181340
scrn3
secernin 3
chr4_-_12286067 0.20 ENSDART00000022646
cnot4b
CCR4-NOT transcription complex, subunit 4b
chr6_+_18298444 0.20 ENSDART00000166018
card14
caspase recruitment domain family, member 14
chr21_-_25774605 0.19 ENSDART00000002128
CLDN4 (1 of many)
zgc:112437
chr14_+_20893065 0.19 ENSDART00000079452
lygl1
lysozyme g-like 1
chr7_+_39684652 0.19 ENSDART00000040946
tbc1d14
TBC1 domain family, member 14
chr24_+_25258904 0.18 ENSDART00000155714
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr1_-_26071535 0.18 ENSDART00000185187
pdcd4a
programmed cell death 4a
chr1_+_33647682 0.18 ENSDART00000114384
znf654
zinc finger protein 654
chr22_-_36856405 0.18 ENSDART00000029588
kng1
kininogen 1
chr16_-_13109749 0.18 ENSDART00000142610
prkcg
protein kinase C, gamma
chr11_-_25539323 0.18 ENSDART00000155785
si:dkey-245f22.3
si:dkey-245f22.3
chr13_+_22480857 0.17 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
ldb3a
LIM domain binding 3a
chr5_-_52243424 0.17 ENSDART00000159078
erap2
endoplasmic reticulum aminopeptidase 2
chr16_+_18535618 0.17 ENSDART00000021596
rxrbb
retinoid x receptor, beta b
chr13_+_30169233 0.17 ENSDART00000181183
pald1b
phosphatase domain containing, paladin 1b
chr17_-_42988356 0.17 ENSDART00000024558
zgc:92137
zgc:92137
chr20_+_28960340 0.17 ENSDART00000147917
gpr176
G protein-coupled receptor 176
chr17_-_43399896 0.17 ENSDART00000156033
ENSDART00000156418
itpk1b
inositol-tetrakisphosphate 1-kinase b
chr15_-_35100858 0.17 ENSDART00000099677
bloc1s3
biogenesis of lysosomal organelles complex-1, subunit 3
chr8_-_16697912 0.17 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr23_+_2778813 0.17 ENSDART00000142621
top1
DNA topoisomerase I
chr20_-_39273987 0.17 ENSDART00000127173
clu
clusterin
chr3_+_32443395 0.17 ENSDART00000188447
prr12b
proline rich 12b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxa3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0090220 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.2 0.6 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 0.8 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 1.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.9 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.4 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.8 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.5 GO:0045824 negative regulation of toll-like receptor signaling pathway(GO:0034122) negative regulation of innate immune response(GO:0045824)
0.1 0.3 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.3 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.4 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 1.1 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.2 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.6 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.3 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.6 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.1 0.7 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.2 GO:0016117 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 0.8 GO:0032094 response to food(GO:0032094)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.1 2.1 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.4 GO:0009914 hormone transport(GO:0009914)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.0 0.2 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.4 GO:0006868 glutamine transport(GO:0006868)
0.0 0.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.4 GO:0045453 bone resorption(GO:0045453)
0.0 0.6 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 2.6 GO:0003341 cilium movement(GO:0003341)
0.0 0.7 GO:0039022 pronephric duct development(GO:0039022)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:1902023 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.4 GO:0032438 melanosome organization(GO:0032438)
0.0 0.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.7 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 1.0 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 1.2 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.0 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.0 GO:1903779 regulation of heart looping(GO:1901207) regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:0030320 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320) cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.2 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.5 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0043202 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.5 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.4 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 2.7 GO:0031514 motile cilium(GO:0031514)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 1.5 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.8 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.2 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.5 GO:0046978 TAP1 binding(GO:0046978)
0.2 1.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.6 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 1.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.6 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.2 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.5 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0099604 ligand-gated calcium channel activity(GO:0099604)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 1.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE