Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for foxa_foxa1_foxa2

Z-value: 0.65

Motif logo

logo of logo of logo of

Transcription factors associated with foxa_foxa1_foxa2

Gene Symbol Gene ID Gene Info
foxa
ENSDARG00000087094 forkhead box A sequence
foxa
ENSDARG00000110743 forkhead box A sequence
foxa
ENSDARG00000115019 forkhead box A sequence
foxa1
ENSDARG00000102138 forkhead box A1
foxa2
ENSDARG00000003411 forkhead box A2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxa2dr11_v1_chr17_-_42568498_42568498-0.965.5e-10Click!
foxa1dr11_v1_chr17_+_10318071_10318071-0.949.2e-09Click!
foxadr11_v1_chr14_-_33981544_339815440.841.2e-05Click!

Activity profile of foxa_foxa1_foxa2 motif

Sorted Z-values of foxa_foxa1_foxa2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_38299385 2.57 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr19_-_43757568 2.53 ENSDART00000058491
ppt1
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr1_+_45707219 2.48 ENSDART00000143363
si:ch211-214c7.4
si:ch211-214c7.4
chr23_-_22523303 2.46 ENSDART00000079019
spsb1
splA/ryanodine receptor domain and SOCS box containing 1
chr15_+_38299563 2.40 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr22_+_24559947 2.00 ENSDART00000169847
wdr47b
WD repeat domain 47b
chr14_+_15155684 2.00 ENSDART00000167966
zgc:158852
zgc:158852
chr16_-_26820634 1.92 ENSDART00000111156
pdp1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr17_+_24036791 1.91 ENSDART00000140767
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr10_+_7709724 1.78 ENSDART00000097670
ggcx
gamma-glutamyl carboxylase
chr17_+_32623931 1.73 ENSDART00000144217
ctsba
cathepsin Ba
chr7_+_67699178 1.69 ENSDART00000160086
zgc:162592
zgc:162592
chr13_-_32726178 1.56 ENSDART00000012232
pdss2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr12_-_48188928 1.49 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr17_-_30652738 1.46 ENSDART00000154960
sh3yl1
SH3 and SYLF domain containing 1
chr23_-_36449111 1.45 ENSDART00000110478
zgc:174906
zgc:174906
chr9_-_6991650 1.44 ENSDART00000081718
slc9a2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr19_+_7549854 1.42 ENSDART00000138866
ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr9_+_33154841 1.42 ENSDART00000132465
dopey2
dopey family member 2
chr12_+_22404108 1.40 ENSDART00000153055
hdlbpb
high density lipoprotein binding protein b
chr24_+_19210001 1.33 ENSDART00000179373
ENSDART00000139299
zgc:162928
zgc:162928
chr16_-_41714988 1.32 ENSDART00000138798
cep85
centrosomal protein 85
chr17_-_15188440 1.28 ENSDART00000151885
wdhd1
WD repeat and HMG-box DNA binding protein 1
chr8_-_25771474 1.25 ENSDART00000193883
suv39h1b
suppressor of variegation 3-9 homolog 1b
chr20_+_46741074 1.24 ENSDART00000145294
si:ch211-57i17.1
si:ch211-57i17.1
chr1_+_45969240 1.24 ENSDART00000042086
arhgef7b
Rho guanine nucleotide exchange factor (GEF) 7b
chr11_-_35171162 1.23 ENSDART00000017393
traip
TRAF-interacting protein
chr5_+_41496490 1.22 ENSDART00000039369
fancg
Fanconi anemia, complementation group G
chr3_+_40255408 1.21 ENSDART00000074746
smcr8a
Smith-Magenis syndrome chromosome region, candidate 8a
chr3_+_46762703 1.17 ENSDART00000133283
prkcsh
protein kinase C substrate 80K-H
chr22_+_105376 1.15 ENSDART00000059140
slc25a20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr5_-_33236637 1.15 ENSDART00000085512
ENSDART00000144694
kank1b
KN motif and ankyrin repeat domains 1b
chr19_-_46091497 1.13 ENSDART00000178772
ENSDART00000167255
ptdss1b
si:dkey-108k24.2
phosphatidylserine synthase 1b
si:dkey-108k24.2
chr18_-_44935174 1.09 ENSDART00000081025
pex16
peroxisomal biogenesis factor 16
chr13_-_23956178 1.05 ENSDART00000133646
phactr2
phosphatase and actin regulator 2
chr16_+_38940758 1.04 ENSDART00000102482
ENSDART00000136215
eny2
enhancer of yellow 2 homolog (Drosophila)
chr7_+_52712807 1.04 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
znf280d
zinc finger protein 280D
chr8_-_30338872 1.04 ENSDART00000137583
dock8
dedicator of cytokinesis 8
chr12_-_48199227 1.02 ENSDART00000171058
pald1a
phosphatase domain containing, paladin 1a
chr8_-_1219815 1.01 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr20_-_52928541 1.00 ENSDART00000162812
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr13_-_23956361 0.99 ENSDART00000101150
phactr2
phosphatase and actin regulator 2
chr18_-_13121983 0.97 ENSDART00000092648
rxylt1
ribitol xylosyltransferase 1
chr5_-_31772559 0.97 ENSDART00000183879
fam102ab
family with sequence similarity 102, member Ab
chr14_-_6931889 0.97 ENSDART00000166439
si:ch211-266k2.1
si:ch211-266k2.1
chr7_-_26601307 0.97 ENSDART00000188934
plscr3b
phospholipid scramblase 3b
chr11_+_11120532 0.97 ENSDART00000026135
ENSDART00000189872
ly75
lymphocyte antigen 75
chr9_+_50110763 0.96 ENSDART00000162990
cobll1b
cordon-bleu WH2 repeat protein-like 1b
chr9_+_42607138 0.96 ENSDART00000138133
ENSDART00000002027
gulp1a
GULP, engulfment adaptor PTB domain containing 1a
chr20_-_28361574 0.96 ENSDART00000103352
vps18
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr6_-_40657653 0.96 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr16_-_35532937 0.95 ENSDART00000193209
ctps1b
CTP synthase 1b
chr20_+_30378803 0.95 ENSDART00000148242
ENSDART00000169140
ENSDART00000062441
rnaseh1
ribonuclease H1
chr16_-_25233515 0.92 ENSDART00000058943
zgc:110182
zgc:110182
chr21_+_520479 0.92 ENSDART00000168054
CABZ01079760.1

chr14_-_16082806 0.92 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr6_+_4371137 0.92 ENSDART00000168973
rbm26
RNA binding motif protein 26
chr9_-_46072805 0.91 ENSDART00000169682
hdac4
histone deacetylase 4
chr2_+_1988036 0.91 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr13_-_33114933 0.91 ENSDART00000140543
ENSDART00000075953
zfyve26
zinc finger, FYVE domain containing 26
chr5_-_31773208 0.87 ENSDART00000137556
ENSDART00000122066
fam102ab
family with sequence similarity 102, member Ab
chr9_+_41459759 0.86 ENSDART00000132501
ENSDART00000100265
nemp2
nuclear envelope integral membrane protein 2
chr20_+_29209767 0.85 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr6_+_4370935 0.85 ENSDART00000192368
rbm26
RNA binding motif protein 26
chr14_+_32918484 0.85 ENSDART00000105721
lnx2b
ligand of numb-protein X 2b
chr21_+_20386865 0.84 ENSDART00000144366
si:dkey-30k6.5
si:dkey-30k6.5
chr1_-_9277986 0.83 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubn1
ubinuclein 1
chr8_-_35960987 0.82 ENSDART00000160503
slc15a4
solute carrier family 15 (oligopeptide transporter), member 4
chr23_-_25686894 0.81 ENSDART00000181420
ENSDART00000088208
lrp1ab
low density lipoprotein receptor-related protein 1Ab
chr23_-_10722664 0.80 ENSDART00000146526
ENSDART00000129022
ENSDART00000104985
foxp1a
forkhead box P1a
chr20_+_29209926 0.80 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr18_-_22094102 0.80 ENSDART00000100904
pard6a
par-6 family cell polarity regulator alpha
chr6_+_38626926 0.79 ENSDART00000190339
atp10a
ATPase phospholipid transporting 10A
chr5_-_23675222 0.79 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr3_-_55525627 0.79 ENSDART00000189234
tex2
testis expressed 2
chr6_-_3998199 0.79 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr1_-_354115 0.79 ENSDART00000141590
ENSDART00000098627
pros1
protein S
chr8_-_42712573 0.78 ENSDART00000132229
ENSDART00000137258
si:ch73-138n13.1
si:ch73-138n13.1
chr4_-_16824556 0.78 ENSDART00000165289
ENSDART00000185839
gys2
glycogen synthase 2
chr6_+_40952031 0.78 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr14_+_7699443 0.76 ENSDART00000123139
brd8
bromodomain containing 8
chr4_-_16824231 0.76 ENSDART00000014007
gys2
glycogen synthase 2
chr6_-_10728057 0.76 ENSDART00000002247
sp3b
Sp3b transcription factor
chr6_+_38626684 0.76 ENSDART00000086533
atp10a
ATPase phospholipid transporting 10A
chr5_+_28271412 0.76 ENSDART00000031727
vamp8
vesicle-associated membrane protein 8 (endobrevin)
chr10_+_11260170 0.74 ENSDART00000155742
hsdl2
hydroxysteroid dehydrogenase like 2
chr19_-_25119443 0.73 ENSDART00000148953
ptp4a3
protein tyrosine phosphatase type IVA, member 3
chr3_-_34528306 0.73 ENSDART00000023039
sept9a
septin 9a
chr20_+_29209615 0.73 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr20_-_25902141 0.73 ENSDART00000142611
ENSDART00000024821
elmsan1a
ELM2 and Myb/SANT-like domain containing 1a
chr5_+_67835595 0.72 ENSDART00000159386
si:ch211-271b14.1
si:ch211-271b14.1
chr15_-_25365570 0.72 ENSDART00000152754
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr2_-_32262287 0.72 ENSDART00000056621
ENSDART00000039717
fam49ba
family with sequence similarity 49, member Ba
chr22_+_1940595 0.72 ENSDART00000163506
znf1167
zinc finger protein 1167
chr17_+_33415319 0.71 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr3_+_54168007 0.71 ENSDART00000109894
olfm2a
olfactomedin 2a
chr4_-_10835620 0.71 ENSDART00000150739
ppfibp1a
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr15_+_40079468 0.70 ENSDART00000154947
ngef
neuronal guanine nucleotide exchange factor
chr15_-_25365319 0.70 ENSDART00000152651
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr14_+_50918769 0.70 ENSDART00000146918
rnf44
ring finger protein 44
chr14_+_34495216 0.70 ENSDART00000147756
wnt8a
wingless-type MMTV integration site family, member 8a
chr10_-_36633882 0.69 ENSDART00000077161
ENSDART00000137688
rsf1b.1
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr7_-_58098814 0.69 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr3_+_19685873 0.67 ENSDART00000006490
tlk2
tousled-like kinase 2
chr9_+_24065855 0.67 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr12_-_28537615 0.66 ENSDART00000067762
MYO1D
si:ch211-94l19.4
chr20_-_28800999 0.65 ENSDART00000049462
rab15
RAB15, member RAS oncogene family
chr17_-_26719821 0.64 ENSDART00000186813
calm1a
calmodulin 1a
chr11_-_11336986 0.64 ENSDART00000016677
zgc:77929
zgc:77929
chr16_-_44673851 0.63 ENSDART00000015139
dcaf13
ddb1 and cul4 associated factor 13
chr5_-_66749535 0.62 ENSDART00000132183
kat5b
K(lysine) acetyltransferase 5b
chr6_+_6780873 0.62 ENSDART00000011865
sec23b
Sec23 homolog B, COPII coat complex component
chr7_-_29723761 0.62 ENSDART00000173560
vps13c
vacuolar protein sorting 13 homolog C (S. cerevisiae)
chr24_+_19542323 0.62 ENSDART00000140379
ENSDART00000142830
sulf1
sulfatase 1
chr2_-_21167652 0.61 ENSDART00000185792
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr19_+_25971000 0.60 ENSDART00000089836
jarid2b
jumonji, AT rich interactive domain 2b
chr22_-_11520405 0.60 ENSDART00000063157
slc26a11
solute carrier family 26 (anion exchanger), member 11
chr11_-_14102131 0.60 ENSDART00000085158
ENSDART00000191962
tmem259
transmembrane protein 259
chr5_+_36650096 0.60 ENSDART00000111414
alkbh6
alkB homolog 6
chr8_-_16725959 0.60 ENSDART00000183593
depdc1a
DEP domain containing 1a
chr1_+_51537250 0.60 ENSDART00000152789
etaa1
ETAA1, ATR kinase activator
chr3_+_32663865 0.59 ENSDART00000190240
si:dkey-16l2.16
si:dkey-16l2.16
chr21_-_30030644 0.59 ENSDART00000190810
CU855895.2

chr17_+_33415542 0.59 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr10_-_15128771 0.58 ENSDART00000101261
spp1
secreted phosphoprotein 1
chr17_-_14966384 0.57 ENSDART00000105064
txndc16
thioredoxin domain containing 16
chr7_+_36898850 0.57 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr23_-_10723009 0.57 ENSDART00000189721
foxp1a
forkhead box P1a
chr16_-_17713859 0.57 ENSDART00000149275
zgc:174935
zgc:174935
chr19_+_7636941 0.56 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr3_-_21280373 0.56 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr20_+_23742574 0.56 ENSDART00000050559
sh3rf1
SH3 domain containing ring finger 1
chr12_+_45238292 0.55 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr19_-_7272921 0.55 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
rxrba
retinoid x receptor, beta a
chr13_-_33207367 0.53 ENSDART00000146138
ENSDART00000109667
ENSDART00000182741
trip11
thyroid hormone receptor interactor 11
chr10_+_11261576 0.53 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr22_+_33135253 0.52 ENSDART00000004504
dag1
dystroglycan 1
chr2_-_4032732 0.52 ENSDART00000158335
rab18b
RAB18B, member RAS oncogene family
chr16_+_31511739 0.52 ENSDART00000049420
ndrg1b
N-myc downstream regulated 1b
chr21_+_26522571 0.51 ENSDART00000134617
adssl
adenylosuccinate synthase, like
chr1_-_8917902 0.51 ENSDART00000137900
grin2ab
glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b
chr5_+_31214341 0.51 ENSDART00000133432
atp2a3
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
chr5_+_52625975 0.51 ENSDART00000170341
ENSDART00000168317
apba1a
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr17_-_4252221 0.51 ENSDART00000152020
gdf3
growth differentiation factor 3
chr21_+_19547806 0.50 ENSDART00000159707
ENSDART00000184869
ENSDART00000181321
ENSDART00000058487
ENSDART00000058485
rai14
retinoic acid induced 14
chr2_-_57227542 0.49 ENSDART00000182675
ENSDART00000159480
btbd2b
BTB (POZ) domain containing 2b
chr6_-_41138854 0.49 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr10_-_14929392 0.49 ENSDART00000137430
smad2
SMAD family member 2
chr23_-_3759345 0.49 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr11_+_18612421 0.48 ENSDART00000110621
ncoa3
nuclear receptor coactivator 3
chr12_-_22238004 0.48 ENSDART00000038310
ormdl3
ORMDL sphingolipid biosynthesis regulator 3
chr22_+_39007533 0.48 ENSDART00000185958
ENSDART00000129848
fam208aa
family with sequence similarity 208, member Aa
chr24_-_17389263 0.47 ENSDART00000122757
cul1b
cullin 1b
chr17_-_37474689 0.47 ENSDART00000103980
crip2
cysteine-rich protein 2
chr6_-_40922971 0.47 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr17_+_25213229 0.47 ENSDART00000110451
arhgef10
Rho guanine nucleotide exchange factor (GEF) 10
chr10_-_17710637 0.46 ENSDART00000147553
stard7
StAR-related lipid transfer (START) domain containing 7
chr17_+_32158951 0.46 ENSDART00000165348
ENSDART00000108736
adam12
ADAM metallopeptidase domain 12
chr3_-_26787430 0.45 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr22_+_1947494 0.45 ENSDART00000159121
si:dkey-15h8.15
si:dkey-15h8.15
chr11_+_35171406 0.45 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr24_-_21172122 0.45 ENSDART00000154259
atp6v1ab
ATPase H+ transporting V1 subunit Ab
chr13_+_37653851 0.45 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
phf3
PHD finger protein 3
chr12_-_28794957 0.45 ENSDART00000020667
osbpl7
oxysterol binding protein-like 7
chr15_+_21712328 0.44 ENSDART00000192553
NKAPD1
zgc:162339
chr17_-_21162821 0.44 ENSDART00000157283
abhd12
abhydrolase domain containing 12
chr23_-_27501923 0.44 ENSDART00000188394
asb8
ankyrin repeat and SOCS box containing 8
chr15_-_28908027 0.44 ENSDART00000182790
ENSDART00000192461
eml2
echinoderm microtubule associated protein like 2
chr6_-_41135215 0.44 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr4_-_9579299 0.43 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
shank3b
SH3 and multiple ankyrin repeat domains 3b
chr20_-_33487729 0.43 ENSDART00000061843
smek1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr17_+_32622933 0.42 ENSDART00000077418
ctsba
cathepsin Ba
chr6_+_49723289 0.42 ENSDART00000190452
stx16
syntaxin 16
chr1_+_11107688 0.41 ENSDART00000109858
knstrn
kinetochore-localized astrin/SPAG5 binding protein
chr15_-_47338769 0.41 ENSDART00000164983
ENSDART00000176289
anapc15
anaphase promoting complex subunit 15
chr9_-_44905867 0.40 ENSDART00000138316
ENSDART00000131252
ENSDART00000179383
ENSDART00000159337
zgc:66484
zgc:66484
chr17_-_21280185 0.39 ENSDART00000123198
hspa12a
heat shock protein 12A
chr12_+_23991639 0.39 ENSDART00000003143
psme4b
proteasome activator subunit 4b
chr14_+_32926385 0.39 ENSDART00000139159
lnx2b
ligand of numb-protein X 2b
chr19_+_32807236 0.38 ENSDART00000008698
stk3
serine/threonine kinase 3 (STE20 homolog, yeast)
chr12_+_35203091 0.38 ENSDART00000153022
ndst2b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
chr25_+_28253844 0.38 ENSDART00000151891
cadps2
Ca++-dependent secretion activator 2
chr23_+_39346774 0.37 ENSDART00000190985
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr21_-_26028205 0.37 ENSDART00000034875
sdf2
stromal cell-derived factor 2
chr2_-_30200206 0.37 ENSDART00000130142
ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr8_+_16676894 0.37 ENSDART00000076586
si:ch211-198n5.11
si:ch211-198n5.11
chr17_+_44030692 0.37 ENSDART00000049503
peli2
pellino E3 ubiquitin protein ligase family member 2
chr4_-_13156971 0.36 ENSDART00000182164
grip1
glutamate receptor interacting protein 1
chr16_+_47207691 0.36 ENSDART00000062507
ica1
islet cell autoantigen 1
chr6_+_51932267 0.36 ENSDART00000156256
angpt4
angiopoietin 4
chr16_+_19029297 0.36 ENSDART00000115263
ENSDART00000114954
rapgef5b
Rap guanine nucleotide exchange factor (GEF) 5b
chr18_-_39702327 0.35 ENSDART00000149158
dmxl2
Dmx-like 2
chr20_+_34502606 0.35 ENSDART00000139739
gorab
golgin, rab6-interacting
chr4_+_14981854 0.35 ENSDART00000067046
cax1
cation/H+ exchanger protein 1
chr23_-_31763753 0.35 ENSDART00000053399
aldh8a1
aldehyde dehydrogenase 8 family, member A1
chr4_+_1619584 0.34 ENSDART00000148486
scaf11
SR-related CTD-associated factor 11
chr13_+_29925397 0.34 ENSDART00000123482
cuedc2
CUE domain containing 2
chr7_+_38808027 0.34 ENSDART00000052323
harbi1
harbinger transposase derived 1
chr15_-_5624361 0.34 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr1_-_28861226 0.33 ENSDART00000075502
timmdc1
translocase of inner mitochondrial membrane domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxa_foxa1_foxa2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:1904184 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.4 1.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.8 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.3 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.2 1.0 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 0.7 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.9 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 2.8 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.2 1.4 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.0 GO:0043476 pigment accumulation(GO:0043476)
0.2 1.4 GO:0042539 hypotonic response(GO:0006971) hypotonic salinity response(GO:0042539)
0.2 0.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 0.8 GO:0070254 mucus secretion(GO:0070254)
0.1 0.7 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.9 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0090266 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.8 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.0 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.5 GO:1900060 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.6 GO:1901976 regulation of cell cycle checkpoint(GO:1901976) regulation of DNA damage checkpoint(GO:2000001)
0.1 1.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.4 GO:0097401 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.1 1.0 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.6 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.1 0.3 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.5 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.6 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.8 GO:0006857 oligopeptide transport(GO:0006857)
0.1 1.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.4 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.6 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.3 GO:0042182 ketone catabolic process(GO:0042182)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.7 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.6 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0045191 regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 0.6 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.4 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.5 GO:0033292 T-tubule organization(GO:0033292)
0.1 1.6 GO:0009749 response to glucose(GO:0009749)
0.1 0.4 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.4 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.3 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.1 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.7 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.5 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 1.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 1.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.6 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.4 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.2 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 1.1 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.3 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.1 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.3 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.2 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.7 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.4 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.9 GO:0048599 oocyte development(GO:0048599)
0.0 0.6 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0032392 DNA geometric change(GO:0032392) DNA duplex unwinding(GO:0032508)
0.0 1.3 GO:0034968 histone lysine methylation(GO:0034968)
0.0 2.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.6 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:2000252 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.2 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.5 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.1 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.0 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0048942 myelination of lateral line nerve axons(GO:0048897) posterior lateral line nerve glial cell differentiation(GO:0048931) myelination of posterior lateral line nerve axons(GO:0048932) lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048938) posterior lateral line nerve glial cell development(GO:0048941) posterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048942)
0.0 0.8 GO:0001841 neural tube formation(GO:0001841)
0.0 1.4 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0045905 positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.5 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.0 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0 0.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0032196 transposition(GO:0032196)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0017177 glucosidase II complex(GO:0017177)
0.2 1.0 GO:0097268 cytoophidium(GO:0097268)
0.2 0.7 GO:0097189 apoptotic body(GO:0097189)
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.2 1.0 GO:0070390 transcription export complex 2(GO:0070390)
0.1 1.0 GO:0030897 HOPS complex(GO:0030897)
0.1 1.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 0.2 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 2.2 GO:0043596 nuclear replication fork(GO:0043596)
0.1 0.5 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.6 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 2.0 GO:0031201 SNARE complex(GO:0031201)
0.0 5.7 GO:0005764 lysosome(GO:0005764)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.9 GO:0030027 lamellipodium(GO:0030027)
0.0 0.7 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.0 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.8 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.4 1.5 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.3 1.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 1.0 GO:0003883 CTP synthase activity(GO:0003883)
0.2 1.7 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.2 3.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 1.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.9 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.4 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.9 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.6 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.3 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0070883 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 2.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 4.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.0 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.0 0.0 GO:0032028 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.0 GO:0051380 norepinephrine binding(GO:0051380)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 1.9 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction