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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxc1a+foxc1b

Z-value: 0.78

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Transcription factors associated with foxc1a+foxc1b

Gene Symbol Gene ID Gene Info
foxc1b
ENSDARG00000055398 forkhead box C1b
foxc1a
ENSDARG00000091481 forkhead box C1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxc1adr11_v1_chr2_-_689047_6890470.971.3e-11Click!
foxc1bdr11_v1_chr20_+_26702377_267023770.978.9e-11Click!

Activity profile of foxc1a+foxc1b motif

Sorted Z-values of foxc1a+foxc1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_34141935 2.71 ENSDART00000127063
fam183a
family with sequence similarity 183, member A
chr2_+_49644803 2.69 ENSDART00000160342
si:ch211-209f23.7
si:ch211-209f23.7
chr10_+_2587234 2.49 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr16_-_31974482 2.37 ENSDART00000189073
styk1
serine/threonine/tyrosine kinase 1
chr8_+_47817454 2.23 ENSDART00000144825
pimr185
Pim proto-oncogene, serine/threonine kinase, related 185
chr13_-_10727550 2.18 ENSDART00000190925
ppm1ba
protein phosphatase, Mg2+/Mn2+ dependent, 1Ba
chr16_+_28727383 1.95 ENSDART00000149753
dcst2
DC-STAMP domain containing 2
chr9_-_48736388 1.88 ENSDART00000022074
dhrs9
dehydrogenase/reductase (SDR family) member 9
chr4_-_25064510 1.73 ENSDART00000025153
gata3
GATA binding protein 3
chr16_-_24815091 1.69 ENSDART00000154269
ENSDART00000131025
kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr16_-_13818061 1.68 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr18_+_25752592 1.60 ENSDART00000111767
si:ch211-39k3.2
si:ch211-39k3.2
chr3_-_18030938 1.59 ENSDART00000013540
si:ch73-141c7.1
si:ch73-141c7.1
chr7_-_16598212 1.49 ENSDART00000128488
e2f8
E2F transcription factor 8
chr3_-_43770876 1.49 ENSDART00000160162
zgc:92162
zgc:92162
chr8_-_48770163 1.39 ENSDART00000160959
pimr184
Pim proto-oncogene, serine/threonine kinase, related 184
chr22_+_26793389 1.37 ENSDART00000165381
pimr69
Pim proto-oncogene, serine/threonine kinase, related 69
chr11_-_38910527 1.36 ENSDART00000143105
pimr126
Pim proto-oncogene, serine/threonine kinase, related 126
chr2_-_24554416 1.32 ENSDART00000052061
cnn2
calponin 2
chr7_+_49695904 1.31 ENSDART00000183550
ENSDART00000126991
ascl1b
achaete-scute family bHLH transcription factor 1b
chr17_+_53250802 1.29 ENSDART00000143819
VASH1
vasohibin 1
chr22_+_20720808 1.27 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr23_-_42752387 1.26 ENSDART00000149781
si:ch73-217n20.1
si:ch73-217n20.1
chr19_-_33370271 1.20 ENSDART00000132628
nkd3l
naked cuticle homolog 3, like
chr21_+_6556635 1.17 ENSDART00000139598
col5a1
procollagen, type V, alpha 1
chr16_+_7662609 1.16 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
bves
blood vessel epicardial substance
chr3_-_16227683 1.14 ENSDART00000111707
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr2_+_6181383 1.07 ENSDART00000153307
si:ch73-344o19.1
si:ch73-344o19.1
chr3_-_16227490 0.96 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr2_-_31614277 0.94 ENSDART00000137054
ENSDART00000131507
ENSDART00000137674
ENSDART00000147041
si:ch211-106h4.5
si:ch211-106h4.5
chr21_-_22114625 0.93 ENSDART00000177426
ENSDART00000135410
elmod1
ELMO/CED-12 domain containing 1
chr8_-_13471916 0.91 ENSDART00000146558
pimr105
Pim proto-oncogene, serine/threonine kinase, related 105
chr19_-_19339285 0.86 ENSDART00000158413
ENSDART00000170479
cspg5b
chondroitin sulfate proteoglycan 5b
chr1_-_25679339 0.85 ENSDART00000161703
ENSDART00000054230
fgg
fibrinogen gamma chain
chr4_+_12358822 0.81 ENSDART00000172557
ENSDART00000150627
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr14_-_46310204 0.80 ENSDART00000188713
ENSDART00000184930
crybb1l1
crystallin, beta B1, like 1
chr20_+_51478939 0.80 ENSDART00000149758
tlr5a
toll-like receptor 5a
chr25_+_16601839 0.80 ENSDART00000008986
atp6v1e1a
ATPase H+ transporting V1 subunit E1a
chr1_-_9109699 0.79 ENSDART00000147833
vap
vascular associated protein
chr4_+_12342173 0.79 ENSDART00000161518
pimr214
Pim proto-oncogene, serine/threonine kinase, related 214
chr12_+_695619 0.78 ENSDART00000161691
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr22_+_38978084 0.73 ENSDART00000025482
arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr15_-_20468302 0.70 ENSDART00000018514
dlc
deltaC
chr11_-_45138857 0.69 ENSDART00000166501
cant1b
calcium activated nucleotidase 1b
chr19_-_26736336 0.68 ENSDART00000109258
ENSDART00000182802
csnk2b
casein kinase 2, beta polypeptide
chr7_+_23907692 0.66 ENSDART00000045479
syt4
synaptotagmin IV
chr24_+_9372292 0.66 ENSDART00000082422
ENSDART00000191127
ENSDART00000180510
si:ch211-285f17.1
si:ch211-285f17.1
chr1_-_54947592 0.66 ENSDART00000129710
crtac1a
cartilage acidic protein 1a
chr1_-_17663108 0.66 ENSDART00000131559
si:dkey-256e7.5
si:dkey-256e7.5
chr8_-_13419049 0.66 ENSDART00000133656
pimr101
Pim proto-oncogene, serine/threonine kinase, related 101
chr15_+_47903864 0.64 ENSDART00000063835
otx5
orthodenticle homolog 5
chr22_-_23000815 0.63 ENSDART00000137111
ptprc
protein tyrosine phosphatase, receptor type, C
chr17_+_12265095 0.63 ENSDART00000153812
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr19_-_10730488 0.61 ENSDART00000126033
slc9a3.1
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 1
chr23_+_18944388 0.60 ENSDART00000104487
cox4i2
cytochrome c oxidase subunit IV isoform 2
chr11_+_583142 0.60 ENSDART00000168157
mkrn2os.2
MKRN2 opposite strand, tandem duplicate 2
chr3_+_26064091 0.60 ENSDART00000143697
si:dkeyp-69e1.8
si:dkeyp-69e1.8
chr7_-_22132265 0.60 ENSDART00000125284
ENSDART00000112978
nlgn2a
neuroligin 2a
chr5_-_28029558 0.60 ENSDART00000078649
abcb9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr21_-_17290941 0.59 ENSDART00000147993
gfi1b
growth factor independent 1B transcription repressor
chr11_+_39135050 0.59 ENSDART00000180571
ENSDART00000189685
cdc42
cell division cycle 42
chr1_-_46326156 0.58 ENSDART00000040284
atp11a
ATPase phospholipid transporting 11A
chr10_+_38512270 0.56 ENSDART00000109752
serpinh1a
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr4_-_14899113 0.54 ENSDART00000137829
si:dkey-14k9.3
si:dkey-14k9.3
chr13_+_28417297 0.54 ENSDART00000043658
slc2a15a
solute carrier family 2 (facilitated glucose transporter), member 15a
chr7_+_20030888 0.53 ENSDART00000192808
slc16a13
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr11_+_16138065 0.53 ENSDART00000188616
pimr204
Pim proto-oncogene, serine/threonine kinase, related 204
chr20_+_51479263 0.53 ENSDART00000148798
tlr5a
toll-like receptor 5a
chr13_+_36680564 0.51 ENSDART00000136030
ENSDART00000006923
atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex subunit s
chr6_+_9398074 0.50 ENSDART00000151772
kalrnb
kalirin RhoGEF kinase b
chr12_-_24060358 0.50 ENSDART00000050831
chac2
ChaC, cation transport regulator homolog 2 (E. coli)
chr22_-_26175237 0.50 ENSDART00000108737
c3b.2
complement component c3b, tandem duplicate 2
chr5_+_30680804 0.50 ENSDART00000078049
pdzd3b
PDZ domain containing 3b
chr16_-_1709328 0.49 ENSDART00000168865
ascc3
activating signal cointegrator 1 complex subunit 3
chr4_+_12333168 0.49 ENSDART00000172455
ENSDART00000146166
pimr214
pimr171
Pim proto-oncogene, serine/threonine kinase, related 214
Pim proto-oncogene, serine/threonine kinase, related 171
chr17_-_17764801 0.49 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr16_-_5721386 0.48 ENSDART00000136655
ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr11_-_11331052 0.48 ENSDART00000081765
ENSDART00000160247
mrpl4
mitochondrial ribosomal protein L4
chr20_+_38276690 0.48 ENSDART00000061437
ccl38.6
chemokine (C-C motif) ligand 38, duplicate 6
chr11_+_11200550 0.47 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr2_-_9816492 0.47 ENSDART00000138472
ENSDART00000124051
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr19_-_5103313 0.47 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr17_-_53439866 0.47 ENSDART00000154826
mycbp
c-myc binding protein
chr18_-_41219790 0.46 ENSDART00000162387
ENSDART00000193753
zbtb38
zinc finger and BTB domain containing 38
chr20_-_48061351 0.45 ENSDART00000164962
prep
prolyl endopeptidase
chr5_+_61941610 0.45 ENSDART00000168808
si:dkeyp-117b8.4
si:dkeyp-117b8.4
chr21_-_22928214 0.45 ENSDART00000182760
dub
duboraya
chr21_-_4918735 0.45 ENSDART00000150936
kcnt1
potassium channel, subfamily T, member 1
chr4_-_73299225 0.45 ENSDART00000174178
ENSDART00000174198
si:cabz01021430.2
si:cabz01021430.2
chr3_+_25825043 0.43 ENSDART00000153749
pik3r6b
phosphoinositide-3-kinase, regulatory subunit 6b
chr14_-_2602445 0.42 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr19_+_164013 0.42 ENSDART00000167379
carmil1
capping protein regulator and myosin 1 linker 1
chr9_+_51180508 0.41 ENSDART00000138990
ifih1
interferon induced with helicase C domain 1
chr5_-_61431809 0.41 ENSDART00000082952
rcc1l
RCC1 like
chr7_+_9981757 0.41 ENSDART00000113429
ENSDART00000173233
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr20_+_10723292 0.40 ENSDART00000152805
si:ch211-182e10.4
si:ch211-182e10.4
chr4_+_57093908 0.40 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr6_-_10828880 0.39 ENSDART00000131458
ENSDART00000020261
chrna1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr25_-_3087556 0.39 ENSDART00000193249
best1
bestrophin 1
chr6_+_18441331 0.39 ENSDART00000171005
si:dkey-31g6.4
si:dkey-31g6.4
chr23_+_25893020 0.39 ENSDART00000144769
pkig
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_22338521 0.39 ENSDART00000176849
si:ch73-380n15.2
si:ch73-380n15.2
chr9_+_13985567 0.37 ENSDART00000102296
cd28
CD28 molecule
chr3_-_1938588 0.37 ENSDART00000013001
ENSDART00000186405
zgc:152753
zgc:152753
chr1_-_14332283 0.37 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr1_+_7540978 0.35 ENSDART00000147770
mylz3
myosin, light polypeptide 3, skeletal muscle
chr13_-_47800342 0.35 ENSDART00000121817
fbln7
fibulin 7
chr10_-_302827 0.34 ENSDART00000157582
emsy
EMSY BRCA2-interacting transcriptional repressor
chr21_-_2310064 0.33 ENSDART00000169520
si:ch211-241b2.1
si:ch211-241b2.1
chr21_-_43606502 0.31 ENSDART00000151030
si:ch73-362m14.4
si:ch73-362m14.4
chr8_-_44015210 0.31 ENSDART00000186879
ENSDART00000188965
ENSDART00000001313
ENSDART00000188902
ENSDART00000185935
ENSDART00000147869
rimbp2
rimbp2
RIMS binding protein 2
RIMS binding protein 2
chr8_-_46525092 0.31 ENSDART00000030482
sult1st2
sulfotransferase family 1, cytosolic sulfotransferase 2
chr23_-_15090782 0.30 ENSDART00000133624
si:ch211-218g4.2
si:ch211-218g4.2
chr9_-_370225 0.30 ENSDART00000163637
si:dkey-11f4.7
si:dkey-11f4.7
chr17_+_45404758 0.29 ENSDART00000147557
tagapa
T cell activation RhoGTPase activating protein a
chr7_-_28463106 0.29 ENSDART00000137799
trim66
tripartite motif containing 66
chr23_+_16910071 0.29 ENSDART00000104793
si:dkey-147f3.8
si:dkey-147f3.8
chr2_-_50372467 0.28 ENSDART00000108900
cntnap2b
contactin associated protein like 2b
chr8_+_53464216 0.28 ENSDART00000169514
cacna1db
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr17_-_50430817 0.28 ENSDART00000154007
si:ch211-235i11.4
si:ch211-235i11.4
chr21_-_26250744 0.28 ENSDART00000044735
gria1b
glutamate receptor, ionotropic, AMPA 1b
chr25_-_31953516 0.28 ENSDART00000110180
duox2
dual oxidase 2
chr16_+_9726038 0.28 ENSDART00000192988
ENSDART00000020859
pip5k1ab
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr25_+_3525494 0.27 ENSDART00000169775
RAB19 (1 of many)
RAB19, member RAS oncogene family
chr6_-_8480815 0.27 ENSDART00000162300
rasal3
RAS protein activator like 3
chr12_-_31794908 0.27 ENSDART00000105583
ENSDART00000153449
nat9
N-acetyltransferase 9 (GCN5-related, putative)
chr18_+_808911 0.27 ENSDART00000172518
cox5ab
cytochrome c oxidase subunit Vab
chr18_+_16986903 0.26 ENSDART00000142088
si:ch211-218c6.8
si:ch211-218c6.8
chr17_-_28097760 0.26 ENSDART00000149861
kdm1a
lysine (K)-specific demethylase 1a
chr9_-_21918963 0.25 ENSDART00000090782
lmo7a
LIM domain 7a
chr21_-_4032650 0.25 ENSDART00000151648
ntng2b
netrin g2b
chr18_+_17754510 0.25 ENSDART00000189372
ENSDART00000135236
ENSDART00000137239
si:ch211-216l23.2
si:ch211-216l23.2
chr1_+_31638274 0.25 ENSDART00000057885
fgf8b
fibroblast growth factor 8 b
chr5_-_54300725 0.24 ENSDART00000163048
slc25a35
solute carrier family 25, member 35
chr13_+_46927350 0.24 ENSDART00000165041
ENSDART00000167931
mtrf1l
mitochondrial translational release factor 1-like
chr17_-_12336987 0.23 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr5_+_39087364 0.23 ENSDART00000004286
anxa3a
annexin A3a
chr5_+_31860043 0.23 ENSDART00000036235
ENSDART00000140541
iscub
iron-sulfur cluster assembly enzyme b
chr12_-_9438227 0.23 ENSDART00000003932
erbb2
erb-b2 receptor tyrosine kinase 2
chr24_-_40726073 0.22 ENSDART00000168100
smyhc2
slow myosin heavy chain 2
chr20_+_28960340 0.22 ENSDART00000147917
gpr176
G protein-coupled receptor 176
chr7_-_17337233 0.22 ENSDART00000050236
ENSDART00000102141
nitr8
novel immune-type receptor 8
chr24_-_10917243 0.22 ENSDART00000144372
asap1b
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr1_+_44911405 0.22 ENSDART00000182465
wu:fc21g02
wu:fc21g02
chr10_+_17714866 0.21 ENSDART00000039969
slc20a1b
solute carrier family 20 (phosphate transporter), member 1b
chr9_-_24244383 0.21 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr15_-_568645 0.21 ENSDART00000156744
cbln18
cerebellin 18
chr7_-_43787616 0.21 ENSDART00000179758
cdh11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr16_-_42004544 0.20 ENSDART00000034544
caspa
caspase a
chr9_-_32659805 0.20 ENSDART00000141482
gzm3.2
granzyme 3, tandem duplicate 2
chr9_-_7421135 0.19 ENSDART00000144600
bin1a
bridging integrator 1a
chr15_-_1590858 0.19 ENSDART00000081875
nnr
nanor
chr4_-_5317006 0.19 ENSDART00000150867
si:ch211-214j24.15
si:ch211-214j24.15
chr8_-_18200003 0.18 ENSDART00000080014
rps8b
ribosomal protein S8b
chr2_+_56139941 0.18 ENSDART00000164741
pgpep1
pyroglutamyl-peptidase I
chr15_+_638457 0.18 ENSDART00000157162
znf1013
zinc finger protein 1013
chr12_+_29236274 0.18 ENSDART00000006505
mxtx2
mix-type homeobox gene 2
chr1_-_37383741 0.18 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr15_-_3976035 0.18 ENSDART00000168061
si:ch73-309g22.1
si:ch73-309g22.1
chr16_+_38119004 0.18 ENSDART00000132087
pogzb
pogo transposable element derived with ZNF domain b
chr17_-_23412705 0.18 ENSDART00000126995
si:ch211-149k12.3
si:ch211-149k12.3
chr8_-_15398760 0.17 ENSDART00000162011
agbl4
ATP/GTP binding protein-like 4
chr11_+_42765963 0.17 ENSDART00000156080
ENSDART00000179888
tdrd3
tudor domain containing 3
chr8_-_51340773 0.17 ENSDART00000060633
kansl3
KAT8 regulatory NSL complex subunit 3
chr9_-_7257877 0.17 ENSDART00000153514
si:ch211-121j5.4
si:ch211-121j5.4
chr5_-_61942482 0.16 ENSDART00000097338
napaa
N-ethylmaleimide-sensitive factor attachment protein, alpha a
chr14_-_44773864 0.16 ENSDART00000158386
si:dkey-109l4.3
si:dkey-109l4.3
chr14_-_38865800 0.16 ENSDART00000173047
gsr
glutathione reductase
chr20_-_15062606 0.16 ENSDART00000175585
ENSDART00000135212
prrc2c
proline-rich coiled-coil 2C
chr5_+_23597144 0.16 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
kat5b
K(lysine) acetyltransferase 5b
chr22_+_29135846 0.14 ENSDART00000143811
baiap2l2b
BAI1-associated protein 2-like 2b
chr15_-_18574716 0.14 ENSDART00000142010
ENSDART00000019006
ncam1b
neural cell adhesion molecule 1b
chr5_-_67629263 0.13 ENSDART00000133753
zbtb20
zinc finger and BTB domain containing 20
chr12_-_22524388 0.13 ENSDART00000020942
shbg
sex hormone-binding globulin
chr13_-_50614639 0.13 ENSDART00000170527
vent
ventral expressed homeobox
chr1_-_23274393 0.13 ENSDART00000147800
ENSDART00000130277
ENSDART00000054340
ENSDART00000054338
rpl9
ribosomal protein L9
chr6_-_51811095 0.13 ENSDART00000161048
psmf1
proteasome inhibitor subunit 1
chr25_+_20216159 0.12 ENSDART00000048642
tnnt2d
troponin T2d, cardiac
chr12_+_20641471 0.12 ENSDART00000133654
calcoco2
calcium binding and coiled-coil domain 2
chr1_-_37383539 0.12 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr23_+_24926407 0.11 ENSDART00000137486
klhl21
kelch-like family member 21
chr13_+_31002658 0.11 ENSDART00000140257
lrrc18a
leucine rich repeat containing 18a
chr1_+_45056371 0.11 ENSDART00000073689
ENSDART00000167309
btr01
bloodthirsty-related gene family, member 1
chr5_-_4219741 0.11 ENSDART00000100093
si:ch211-283g2.2
si:ch211-283g2.2
chr22_+_15720381 0.10 ENSDART00000128149
fam32a
family with sequence similarity 32, member A
chr6_+_72040 0.10 ENSDART00000122957
crygm4
crystallin, gamma M4
chr20_-_19365875 0.10 ENSDART00000063703
ENSDART00000187707
ENSDART00000161065
si:dkey-71h2.2
si:dkey-71h2.2
chr20_-_35578435 0.09 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr12_-_37941733 0.09 ENSDART00000130167
CABZ01046949.1

chr20_-_3166168 0.09 ENSDART00000134137
si:ch73-212j7.3
si:ch73-212j7.3
chr18_-_16792561 0.09 ENSDART00000145546
ampd3b
adenosine monophosphate deaminase 3b
chr21_-_30111134 0.09 ENSDART00000014223
slc23a1
solute carrier family 23 (ascorbic acid transporter), member 1
chr2_-_27473645 0.09 ENSDART00000186152
CU469530.2

chr16_-_13992646 0.09 ENSDART00000139623
si:dkey-85k15.6
si:dkey-85k15.6
chr9_+_15893093 0.08 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
si:dkey-14o1.20
chr24_-_36271352 0.08 ENSDART00000153682
ENSDART00000155892
si:ch211-40k21.5
si:ch211-40k21.5
chr1_+_18550864 0.08 ENSDART00000142515
si:dkey-192k22.2
si:dkey-192k22.2
chr14_-_22390821 0.08 ENSDART00000054396
fbxl3l
F-box and leucine-rich repeat protein 3, like
chr17_-_465285 0.08 ENSDART00000168718
chrm5a
cholinergic receptor, muscarinic 5a
chr15_-_12319065 0.08 ENSDART00000162973
ENSDART00000170543
fxyd6
FXYD domain containing ion transport regulator 6

Network of associatons between targets according to the STRING database.

First level regulatory network of foxc1a+foxc1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.3 1.3 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.2 1.7 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.2 1.2 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.2 1.5 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.2 0.5 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 1.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.4 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.5 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.7 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 0.5 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 2.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 1.9 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 0.9 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.4 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.6 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 0.2 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.4 GO:0032648 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 0.2 GO:0048940 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.1 0.6 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.6 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.6 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 2.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0086009 membrane repolarization(GO:0086009)
0.0 0.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.0 10.6 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.5 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 1.3 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.6 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.4 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.6 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation(GO:0050731)
0.0 0.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.3 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.1 2.7 GO:0097546 ciliary base(GO:0097546)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 0.4 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.6 GO:0031526 brush border membrane(GO:0031526)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 2.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.8 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.5 GO:0031430 M band(GO:0031430)
0.0 2.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.7 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.2 1.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.6 GO:0046978 TAP1 binding(GO:0046978)
0.2 1.7 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 1.5 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.6 GO:0048039 ubiquinone binding(GO:0048039)
0.2 0.5 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.5 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 2.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.2 GO:0030552 cAMP binding(GO:0030552)
0.1 0.2 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 2.2 GO:0030145 manganese ion binding(GO:0030145)
0.1 0.6 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases