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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxd2_foxd5

Z-value: 1.40

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Transcription factors associated with foxd2_foxd5

Gene Symbol Gene ID Gene Info
foxd2
ENSDARG00000058133 forkhead box D2
foxd5
ENSDARG00000042485 forkhead box D5
foxd5
ENSDARG00000109712 forkhead box D5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxd5dr11_v1_chr8_+_30452945_304529450.931.8e-08Click!
foxd2dr11_v1_chr8_+_19674369_196743690.806.6e-05Click!

Activity profile of foxd2_foxd5 motif

Sorted Z-values of foxd2_foxd5 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_8264751 8.96 ENSDART00000091628
ccdc151
coiled-coil domain containing 151
chr5_+_67662430 6.88 ENSDART00000137700
ENSDART00000142586
si:dkey-70b23.2
si:dkey-70b23.2
chr4_+_12013043 6.19 ENSDART00000130692
cry1aa
cryptochrome circadian clock 1aa
chr10_+_26973063 4.43 ENSDART00000143162
ENSDART00000186210
tm7sf2
transmembrane 7 superfamily member 2
chr10_+_26972755 4.43 ENSDART00000042162
tm7sf2
transmembrane 7 superfamily member 2
chr2_-_40191603 4.29 ENSDART00000180691
si:ch211-122l24.6
si:ch211-122l24.6
chr14_-_4121052 4.05 ENSDART00000167074
irf2
interferon regulatory factor 2
chr12_-_30583668 3.88 ENSDART00000153406
casp7
caspase 7, apoptosis-related cysteine peptidase
chr25_+_19149241 3.71 ENSDART00000184982
ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr24_+_26345427 3.35 ENSDART00000089756
lrrc34
leucine rich repeat containing 34
chr11_-_25730416 3.35 ENSDART00000191612
brpf3a
bromodomain and PHD finger containing, 3a
chr25_-_7759453 2.96 ENSDART00000142439
ENSDART00000021577
phf21ab
PHD finger protein 21Ab
chr13_+_32446169 2.83 ENSDART00000143325
nt5c1ba
5'-nucleotidase, cytosolic IB a
chr11_+_6295370 2.81 ENSDART00000139882
ranbp3a
RAN binding protein 3a
chr5_+_13385837 2.79 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr5_-_29671586 2.70 ENSDART00000098336
spaca9
sperm acrosome associated 9
chr15_-_37829160 2.58 ENSDART00000099425
ctrl
chymotrypsin-like
chr3_+_36424055 2.57 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr20_-_52603094 2.57 ENSDART00000136945
ENSDART00000133798
si:dkey-235d18.6
si:dkey-235d18.6
chr14_-_4120636 2.52 ENSDART00000059230
irf2
interferon regulatory factor 2
chr8_+_16004551 2.48 ENSDART00000165141
elavl4
ELAV like neuron-specific RNA binding protein 4
chr24_+_26345609 2.43 ENSDART00000186844
lrrc34
leucine rich repeat containing 34
chr6_+_2097690 2.42 ENSDART00000193770
tgm2b
transglutaminase 2b
chr19_+_9186175 2.34 ENSDART00000039325
hcn3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr19_+_816208 2.28 ENSDART00000093304
nrm
nurim
chr8_-_44586981 2.25 ENSDART00000026831
ENSDART00000113945
rsph14
radial spoke head 14 homolog
chr11_+_8660158 2.24 ENSDART00000169141
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr5_+_29671681 2.24 ENSDART00000043096
ak8
adenylate kinase 8
chr22_-_15562933 2.18 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr25_+_24250247 2.13 ENSDART00000064646
tmem86a
transmembrane protein 86A
chr16_-_13388821 2.13 ENSDART00000144062
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr4_-_16412084 2.09 ENSDART00000188460
dcn
decorin
chr6_+_24661736 2.07 ENSDART00000169283
znf644b
zinc finger protein 644b
chr24_-_22756508 2.03 ENSDART00000035409
ENSDART00000146247
zc2hc1a
zinc finger, C2HC-type containing 1A
chr20_+_34717403 1.99 ENSDART00000034252
pnocb
prepronociceptin b
chr16_+_43139504 1.98 ENSDART00000065643
dbf4
DBF4 zinc finger
chr20_-_51355465 1.92 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
tcte1
t-complex-associated-testis-expressed 1
chr20_-_22778394 1.90 ENSDART00000152645
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr14_+_11457500 1.77 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr1_-_35924495 1.73 ENSDART00000184424
smad1
SMAD family member 1
chr8_+_7975745 1.66 ENSDART00000137920
si:ch211-169p10.1
si:ch211-169p10.1
chr21_+_35215810 1.64 ENSDART00000135256
ubtd2
ubiquitin domain containing 2
chr5_-_22027357 1.63 ENSDART00000023306
asb12a
ankyrin repeat and SOCS box-containing 12a
chr24_+_5840258 1.62 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr12_-_28848015 1.62 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr15_+_28368823 1.59 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr14_+_46410766 1.57 ENSDART00000032342
anxa5a
annexin A5a
chr14_+_21107032 1.57 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldob
aldolase b, fructose-bisphosphate
chr11_+_41858807 1.53 ENSDART00000161605
iffo2b
intermediate filament family orphan 2b
chr15_+_24691088 1.49 ENSDART00000110618
LRRC75A
si:dkey-151p21.7
chr22_-_17595310 1.42 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr15_+_28368644 1.41 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr5_-_14344647 1.39 ENSDART00000188456
tet3
tet methylcytosine dioxygenase 3
chr16_-_7692568 1.37 ENSDART00000148980
pimr209
Pim proto-oncogene, serine/threonine kinase, related 209
chr3_-_16289826 1.27 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr14_+_11458044 1.26 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr23_-_4925641 1.22 ENSDART00000140861
ENSDART00000060718
taz
tafazzin
chr13_+_32144370 1.21 ENSDART00000020270
osr1
odd-skipped related transciption factor 1
chr10_-_8295294 1.20 ENSDART00000075412
ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr2_-_30693742 1.20 ENSDART00000090292
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr17_+_21964472 1.14 ENSDART00000063704
ENSDART00000188904
crip3
cysteine-rich protein 3
chr10_-_8294965 1.14 ENSDART00000167380
plpp1a
phospholipid phosphatase 1a
chr16_+_11724230 1.12 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr22_-_13042992 1.09 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr23_-_26077038 1.08 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr16_-_44349845 1.08 ENSDART00000170932
rims2a
regulating synaptic membrane exocytosis 2a
chr3_-_60711127 1.08 ENSDART00000184119
ubald2
UBA-like domain containing 2
chr23_-_16960972 1.07 ENSDART00000142546
cdc42l2
cell division cycle 42 like 2
chr5_-_51756210 1.06 ENSDART00000163464
lhfpl2b
LHFPL tetraspan subfamily member 2b
chr15_-_15968883 1.01 ENSDART00000166583
ENSDART00000154042
synrg
synergin, gamma
chr4_+_12013642 1.01 ENSDART00000067281
cry1aa
cryptochrome circadian clock 1aa
chr13_-_30662403 1.00 ENSDART00000012457
si:dkey-275b16.2
si:dkey-275b16.2
chr2_-_127945 0.99 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr1_+_33697170 0.99 ENSDART00000131664
NSUN3
NOP2/Sun RNA methyltransferase family member 3
chr17_-_24564674 0.95 ENSDART00000105435
ENSDART00000135086
abch1
ATP-binding cassette, sub-family H, member 1
chr19_-_31402429 0.94 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr3_-_15081874 0.93 ENSDART00000192532
nme4
NME/NM23 nucleoside diphosphate kinase 4
chr2_-_9748039 0.93 ENSDART00000134870
si:ch1073-170o4.1
si:ch1073-170o4.1
chr12_-_34887943 0.91 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr23_-_44219902 0.91 ENSDART00000185874
zgc:158659
zgc:158659
chr10_+_33744098 0.89 ENSDART00000147775
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr14_-_41556720 0.88 ENSDART00000149244
itga6l
integrin, alpha 6, like
chr5_-_11943750 0.84 ENSDART00000074979
rnft2
ring finger protein, transmembrane 2
chr16_-_19373310 0.83 ENSDART00000148294
dnah11
dynein, axonemal, heavy chain 11
chr6_-_40098641 0.82 ENSDART00000017402
ip6k2b
inositol hexakisphosphate kinase 2b
chr4_-_25215968 0.82 ENSDART00000066932
ENSDART00000066933
itih2
inter-alpha-trypsin inhibitor heavy chain 2
chr23_-_20258490 0.82 ENSDART00000147326
lamb2
laminin, beta 2 (laminin S)
chr14_+_34966598 0.82 ENSDART00000004550
rnf145a
ring finger protein 145a
chr20_+_39375280 0.81 ENSDART00000172434
pimr131
Pim proto-oncogene, serine/threonine kinase, related 131
chr22_-_11438627 0.81 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr8_+_16004154 0.80 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
elavl4
ELAV like neuron-specific RNA binding protein 4
chr24_+_12133814 0.80 ENSDART00000158562
ENSDART00000159029
ENSDART00000168248
lztfl1
leucine zipper transcription factor-like 1
chr23_+_20705849 0.79 ENSDART00000079538
ccdc30
coiled-coil domain containing 30
chr23_-_42810664 0.77 ENSDART00000102328
pfkfb2a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr9_+_45789887 0.76 ENSDART00000135202
si:dkey-34f9.3
si:dkey-34f9.3
chr3_+_41917499 0.74 ENSDART00000028673
lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_13013123 0.71 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr4_-_12723585 0.70 ENSDART00000185639
mgst1.2
microsomal glutathione S-transferase 1.2
chr22_-_23668356 0.68 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr11_-_38914265 0.68 ENSDART00000141229
si:ch211-122l14.4
si:ch211-122l14.4
chr6_+_40671336 0.67 ENSDART00000111639
ENSDART00000186617
rereb
arginine-glutamic acid dipeptide (RE) repeats b
chr6_-_40697585 0.66 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr5_+_54400971 0.65 ENSDART00000169695
bspry
B-box and SPRY domain containing
chr25_+_29160102 0.65 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr18_-_46354269 0.64 ENSDART00000010813
foxa3
forkhead box A3
chr17_-_10073926 0.64 ENSDART00000166081
ENSDART00000161574
zgc:109986
zgc:109986
chr21_+_44684577 0.63 ENSDART00000099528
spry4
sprouty homolog 4 (Drosophila)
chr10_+_36650222 0.62 ENSDART00000126963
ucp3
uncoupling protein 3
chr5_+_43530388 0.61 ENSDART00000190254
ENSDART00000097618
ENSDART00000133006
si:dkey-40c11.2
si:dkey-40c11.2
chr3_+_34683096 0.60 ENSDART00000084432
dusp3b
dual specificity phosphatase 3b
chr9_+_22364997 0.60 ENSDART00000188054
ENSDART00000046116
crygs3
crystallin, gamma S3
chr14_-_26377044 0.60 ENSDART00000022236
emx3
empty spiracles homeobox 3
chr22_+_31059919 0.59 ENSDART00000077063
sec13
SEC13 homolog, nuclear pore and COPII coat complex component
chr3_-_41292569 0.58 ENSDART00000111856
sdk1a
sidekick cell adhesion molecule 1a
chr20_-_25436389 0.58 ENSDART00000153266
itsn2a
intersectin 2a
chr21_+_17110598 0.56 ENSDART00000101282
ENSDART00000191864
bcr
breakpoint cluster region
chr25_+_4760489 0.56 ENSDART00000167399
FP245455.1

chr16_+_21330634 0.55 ENSDART00000191285
ENSDART00000183267
osbpl3b
oxysterol binding protein-like 3b
chr5_+_26795465 0.55 ENSDART00000053001
tcn2
transcobalamin II
chr24_+_7631797 0.54 ENSDART00000187464
cavin1b
caveolae associated protein 1b
chr4_+_57093908 0.54 ENSDART00000170198
si:ch211-238e22.5
si:ch211-238e22.5
chr3_+_39566999 0.52 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr24_-_35707552 0.50 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr19_+_43359075 0.50 ENSDART00000148287
ENSDART00000149856
ENSDART00000188236
ENSDART00000136695
ENSDART00000193859
yrk
Yes-related kinase
chr14_-_40389699 0.49 ENSDART00000181581
ENSDART00000173398
pcdh19
protocadherin 19
chr2_-_48171112 0.49 ENSDART00000156258
pfkpb
phosphofructokinase, platelet b
chr16_+_46492994 0.45 ENSDART00000134734
rpz5
rapunzel 5
chr20_+_2950005 0.45 ENSDART00000135919
amd1
adenosylmethionine decarboxylase 1
chr18_-_16181952 0.43 ENSDART00000157824
slc6a15
solute carrier family 6 (neutral amino acid transporter), member 15
chr7_-_17600415 0.43 ENSDART00000080717
nitr6b
novel immune-type receptor 6b
chr22_-_38819603 0.42 ENSDART00000104437
si:ch211-262h13.5
si:ch211-262h13.5
chr21_-_32284532 0.42 ENSDART00000190676
clk4b
CDC-like kinase 4b
chr19_-_22387141 0.41 ENSDART00000151234
eppk1
epiplakin 1
chr14_-_33613794 0.41 ENSDART00000010022
xpnpep2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr20_+_16721933 0.40 ENSDART00000063950
psmc1b
proteasome 26S subunit, ATPase 1b
chr19_+_32856907 0.40 ENSDART00000148232
rpl30
ribosomal protein L30
chr16_-_35952789 0.38 ENSDART00000180118
eva1ba
eva-1 homolog Ba (C. elegans)
chr4_-_7212875 0.38 ENSDART00000161297
lrrn3b
leucine rich repeat neuronal 3b
chr4_-_5913338 0.37 ENSDART00000183590
arl1
ADP-ribosylation factor-like 1
chr12_-_22524388 0.37 ENSDART00000020942
shbg
sex hormone-binding globulin
chr3_-_50863370 0.37 ENSDART00000169771
ENSDART00000165083
pmp22a
peripheral myelin protein 22a
chr16_-_19349318 0.36 ENSDART00000020821
dnah11
dynein, axonemal, heavy chain 11
chr4_-_6373735 0.35 ENSDART00000140100
MDFIC
si:ch73-156e19.1
chr18_-_5111449 0.35 ENSDART00000046902
pdcd10a
programmed cell death 10a
chr8_+_23703464 0.34 ENSDART00000132584
ppardb
peroxisome proliferator-activated receptor delta b
chr6_+_37754763 0.34 ENSDART00000110770
herc2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr12_+_29173523 0.34 ENSDART00000153212
adgra1a
adhesion G protein-coupled receptor A1a
chr19_+_7043634 0.33 ENSDART00000133954
mhc1uka
major histocompatibility complex class I UKA
chr16_+_23975930 0.33 ENSDART00000147858
ENSDART00000144347
ENSDART00000115270
apoc4
apolipoprotein C-IV
chr4_-_9867476 0.33 ENSDART00000091630
fbxo18
F-box protein, helicase, 18
chr1_-_37087966 0.33 ENSDART00000172111
ENSDART00000160056
nr3c2
nuclear receptor subfamily 3, group C, member 2
chr20_+_26881600 0.32 ENSDART00000174799
serpinb1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr14_+_52481288 0.32 ENSDART00000169164
ENSDART00000159297
tcerg1a
transcription elongation regulator 1a (CA150)
chr17_-_37052622 0.32 ENSDART00000186408
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr13_+_29773153 0.31 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
pax2a
paired box 2a
chr4_-_9867785 0.29 ENSDART00000133169
ENSDART00000185905
ENSDART00000185204
ENSDART00000180753
fbxo18
F-box protein, helicase, 18
chr10_-_35236949 0.28 ENSDART00000145804
ypel2a
yippee-like 2a
chr1_-_656693 0.28 ENSDART00000170483
ENSDART00000166786
appa
amyloid beta (A4) precursor protein a
chr14_-_33894915 0.28 ENSDART00000143290
urp1
urotensin-related peptide 1
chr21_+_27416284 0.28 ENSDART00000077593
ENSDART00000108763
cfb
complement factor B
chr15_+_23911655 0.27 ENSDART00000156304
si:ch1073-145m9.1
si:ch1073-145m9.1
chr21_-_18993110 0.26 ENSDART00000144086
si:ch211-222n4.6
si:ch211-222n4.6
chr24_+_13642126 0.26 ENSDART00000126769
trpa1b
transient receptor potential cation channel, subfamily A, member 1b
chr17_+_13088594 0.26 ENSDART00000193207
gemin2
gem (nuclear organelle) associated protein 2
chr18_+_19974289 0.25 ENSDART00000090334
ENSDART00000192982
skor1b
SKI family transcriptional corepressor 1b
chr19_+_11984725 0.25 ENSDART00000185960
spag1a
sperm associated antigen 1a
chr24_+_34970680 0.24 ENSDART00000113014
rb1cc1
RB1-inducible coiled-coil 1
chr12_+_23424108 0.24 ENSDART00000077732
bambia
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr11_-_20987378 0.23 ENSDART00000110140
taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_-_24053404 0.23 ENSDART00000168511
si:dkey-44g17.6
si:dkey-44g17.6
chr9_-_16109001 0.22 ENSDART00000053473
upp2
uridine phosphorylase 2
chr8_-_16697615 0.22 ENSDART00000187929
rpe65b
retinal pigment epithelium-specific protein 65b
chr8_-_16499508 0.22 ENSDART00000108659
ttc39a
tetratricopeptide repeat domain 39A
chr8_+_23142946 0.22 ENSDART00000152933
si:ch211-196c10.13
si:ch211-196c10.13
chr18_-_24988645 0.22 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr19_-_42238440 0.22 ENSDART00000132591
si:ch211-191i18.4
si:ch211-191i18.4
chr15_-_16121496 0.20 ENSDART00000128624
sgk494a
uncharacterized serine/threonine-protein kinase SgK494a
chr20_+_43083745 0.20 ENSDART00000139014
ENSDART00000153438
moxd1l
monooxygenase, DBH-like 1, like
chr18_+_13837746 0.20 ENSDART00000169552
cdh13
cadherin 13, H-cadherin (heart)
chr7_+_32722227 0.20 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr21_-_39327223 0.20 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr25_-_18778356 0.19 ENSDART00000111425
fbxl13
F-box and leucine-rich repeat protein 13
chr19_-_3874986 0.19 ENSDART00000161830
thrap3b
thyroid hormone receptor associated protein 3b
chr22_-_15280638 0.19 ENSDART00000063008
mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_+_33314925 0.19 ENSDART00000148590
coro2ba
coronin, actin binding protein, 2Ba
chr5_+_32206378 0.19 ENSDART00000126873
ENSDART00000051361
myhz2
myosin, heavy polypeptide 2, fast muscle specific
chr12_+_2648043 0.18 ENSDART00000082220
gdf2
growth differentiation factor 2
chr8_-_47329755 0.17 ENSDART00000060853
pex10
peroxisomal biogenesis factor 10
chr6_+_54187643 0.17 ENSDART00000056830
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr16_+_38119004 0.16 ENSDART00000132087
pogzb
pogo transposable element derived with ZNF domain b
chr20_-_3166168 0.16 ENSDART00000134137
si:ch73-212j7.3
si:ch73-212j7.3
chr7_+_22637515 0.15 ENSDART00000158698
si:dkey-112a7.5
si:dkey-112a7.5
chr14_-_1635296 0.15 ENSDART00000186658
LO018564.1

chr20_+_27647436 0.14 ENSDART00000180557
ENSDART00000185628
mthfd1a
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr20_+_36233873 0.13 ENSDART00000131867
cnih3
cornichon family AMPA receptor auxiliary protein 3
chr22_+_2660505 0.13 ENSDART00000135555
ENSDART00000031485
znf1162
zinc finger protein 1162
chr13_+_32740509 0.13 ENSDART00000076423
ENSDART00000160138
sobpa
sine oculis binding protein homolog (Drosophila) a
chr14_-_41556533 0.13 ENSDART00000074401
itga6l
integrin, alpha 6, like
chr5_+_4575800 0.13 ENSDART00000180952
cst14b.2
cystatin 14b, tandem duplicate 2
chr3_+_15828999 0.13 ENSDART00000104397
tmem11
transmembrane protein 11

Network of associatons between targets according to the STRING database.

First level regulatory network of foxd2_foxd5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0048389 intermediate mesoderm development(GO:0048389)
0.3 8.9 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.3 2.0 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.3 1.4 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.3 2.8 GO:0006611 protein export from nucleus(GO:0006611)
0.2 3.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.2 2.8 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 0.6 GO:0048785 hatching gland development(GO:0048785)
0.2 1.9 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 0.6 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 0.5 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.2 1.6 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 0.7 GO:0055016 hypochord development(GO:0055016)
0.1 3.9 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 0.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.3 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 2.1 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 1.2 GO:0032048 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 2.4 GO:0018149 peptide cross-linking(GO:0018149)
0.1 2.3 GO:0060324 face development(GO:0060324)
0.1 0.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 2.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 3.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 1.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.3 GO:0007635 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.3 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.1 0.8 GO:1903828 negative regulation of cellular protein localization(GO:1903828)
0.1 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 2.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.1 0.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 2.8 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.5 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.9 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.1 0.2 GO:0046333 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 1.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.6 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.9 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.5 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.9 GO:0032418 lysosome localization(GO:0032418)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0016123 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.1 2.9 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.1 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.1 1.6 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.5 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 3.0 GO:0007338 single fertilization(GO:0007338)
0.0 0.8 GO:0016203 muscle attachment(GO:0016203)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.8 GO:0014823 response to activity(GO:0014823)
0.0 0.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0008343 adult feeding behavior(GO:0008343)
0.0 2.2 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.0 2.0 GO:0071696 ectodermal placode development(GO:0071696)
0.0 0.6 GO:0031297 replication fork processing(GO:0031297)
0.0 1.9 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 1.3 GO:0072175 epithelial tube formation(GO:0072175)
0.0 0.6 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.6 GO:0021952 forebrain neuron differentiation(GO:0021879) central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0044206 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.1 GO:0090342 regulation of cell aging(GO:0090342)
0.0 0.2 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 0.0 GO:0072020 proximal straight tubule development(GO:0072020)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0030168 platelet activation(GO:0030168)
0.0 2.3 GO:0006814 sodium ion transport(GO:0006814)
0.0 2.7 GO:0006914 autophagy(GO:0006914)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 2.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 9.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 3.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.9 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.3 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.9 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 3.3 GO:0043204 perikaryon(GO:0043204)
0.1 2.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 5.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 2.0 GO:0043679 axon terminus(GO:0043679)
0.1 1.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.2 GO:0031514 motile cilium(GO:0031514)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 2.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.9 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.0 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.4 2.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.4 1.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.3 8.9 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.3 1.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 2.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.3 2.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.2 3.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 3.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.2 0.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.0 GO:0046592 polyamine oxidase activity(GO:0046592)
0.2 1.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.2 0.6 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 2.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 2.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 2.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.2 GO:0031628 opioid receptor binding(GO:0031628)
0.1 1.0 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.7 GO:0070411 I-SMAD binding(GO:0070411)
0.1 3.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 1.3 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 2.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 2.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.8 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.2 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.1 2.3 GO:0005272 sodium channel activity(GO:0005272)
0.1 0.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.9 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 4.5 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.1 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0070643 vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.3 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.4 8.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.4 6.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.