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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxo3b+foxo6a+foxo6b

Z-value: 0.46

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Transcription factors associated with foxo3b+foxo6a+foxo6b

Gene Symbol Gene ID Gene Info
foxo6b
ENSDARG00000024619 forkhead box O6 b
foxo3b
ENSDARG00000042904 forkhead box O3b
foxo6a
ENSDARG00000100486 forkhead box O6 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxo6adr11_v1_chr16_-_7362806_7362806-0.881.4e-06Click!
foxo6bdr11_v1_chr19_+_15571290_15571290-0.493.8e-02Click!
foxo3bdr11_v1_chr20_-_32332736_32332736-0.428.5e-02Click!

Activity profile of foxo3b+foxo6a+foxo6b motif

Sorted Z-values of foxo3b+foxo6a+foxo6b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_28322986 1.80 ENSDART00000134710
birc5b
baculoviral IAP repeat containing 5b
chr22_+_25753972 1.39 ENSDART00000188417
AL929192.2

chr15_+_38299563 1.27 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr15_+_38299385 1.20 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr5_+_25733774 1.05 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr9_+_27720428 1.03 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr9_+_426392 0.99 ENSDART00000172515
bzw1b
basic leucine zipper and W2 domains 1b
chr8_-_16464453 0.98 ENSDART00000098691
rnf11b
ring finger protein 11b
chr21_-_17037907 0.87 ENSDART00000101263
ube2g1b
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr12_-_48188928 0.84 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr9_-_27410597 0.79 ENSDART00000135652
ENSDART00000042297
kdelc1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr2_+_22409249 0.78 ENSDART00000182915
zgc:56628
zgc:56628
chr23_-_36670369 0.78 ENSDART00000006881
zbtb39
zinc finger and BTB domain containing 39
chr2_-_7131657 0.75 ENSDART00000175565
ENSDART00000092116
extl2
exostosin-like glycosyltransferase 2
chr10_-_25570647 0.74 ENSDART00000134215
grik1a
glutamate receptor, ionotropic, kainate 1a
chr7_-_20241346 0.73 ENSDART00000173619
ENSDART00000127699
si:ch73-335l21.4
si:ch73-335l21.4
chr25_-_36261836 0.73 ENSDART00000179411
dus2
dihydrouridine synthase 2
chr25_-_8160030 0.72 ENSDART00000067159
tph1a
tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a
chr5_-_12031174 0.69 ENSDART00000159896
castor1
cytosolic arginine sensor for mTORC1 subunit 1
chr11_-_23697217 0.68 ENSDART00000124810
pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr14_-_6402769 0.67 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr14_-_45551572 0.67 ENSDART00000111410
ganab
glucosidase, alpha; neutral AB
chr23_+_36308428 0.67 ENSDART00000134607
hnrnpa1b
heterogeneous nuclear ribonucleoprotein A1b
chr19_-_13286722 0.61 ENSDART00000168296
ENSDART00000158330
zfpm2b
zinc finger protein, FOG family member 2b
chr12_+_18970790 0.58 ENSDART00000153279
ENSDART00000153235
ENSDART00000078494
l3mbtl2
l(3)mbt-like 2 (Drosophila)
chr7_-_41881177 0.56 ENSDART00000174258
ENSDART00000018972
zgc:92818
zgc:92818
chr23_-_912817 0.56 ENSDART00000192851
rhoac
ras homolog gene family, member Ac
chr2_-_37478418 0.54 ENSDART00000146103
dapk3
death-associated protein kinase 3
chr20_-_24165509 0.53 ENSDART00000124919
map3k7
mitogen-activated protein kinase kinase kinase 7
chr17_+_51746830 0.52 ENSDART00000184230
odc1
ornithine decarboxylase 1
chr5_+_29652513 0.52 ENSDART00000035400
tsc1a
TSC complex subunit 1a
chr22_-_21676364 0.51 ENSDART00000183668
tle2b
transducin like enhancer of split 2b
chr11_+_14343445 0.51 ENSDART00000171347
ENSDART00000170547
si:ch211-262i1.6
si:ch211-262i1.6
chr12_+_17603528 0.50 ENSDART00000111565
pms2
PMS1 homolog 2, mismatch repair system component
chr6_-_41138854 0.49 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr7_+_69449814 0.49 ENSDART00000109644
ctdnep1b
CTD nuclear envelope phosphatase 1b
chr2_-_38080075 0.48 ENSDART00000056544
tox4a
TOX high mobility group box family member 4 a
chr12_-_28799642 0.48 ENSDART00000066303
mrpl10
mitochondrial ribosomal protein L10
chr19_-_7441686 0.47 ENSDART00000168194
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr9_+_24088062 0.47 ENSDART00000126198
lrrfip1a
leucine rich repeat (in FLII) interacting protein 1a
chr5_-_25733745 0.46 ENSDART00000051566
zgc:101016
zgc:101016
chr24_+_19414561 0.45 ENSDART00000193157
sulf1
sulfatase 1
chr16_+_46410520 0.45 ENSDART00000131072
rpz2
rapunzel 2
chr1_+_10018466 0.44 ENSDART00000113551
trim2b
tripartite motif containing 2b
chr24_+_32411753 0.44 ENSDART00000058530
neurod6a
neuronal differentiation 6a
chr5_+_28433215 0.42 ENSDART00000165072
ENSDART00000168005
nsmfb
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr23_-_12158685 0.42 ENSDART00000135035
fam217b
family with sequence similarity 217, member B
chr12_+_46582168 0.42 ENSDART00000189402
ush1gb
Usher syndrome 1Gb (autosomal recessive)
chr19_-_30447611 0.42 ENSDART00000073705
ENSDART00000048977
ENSDART00000191237
abcf1
ATP-binding cassette, sub-family F (GCN20), member 1
chr13_-_13030851 0.42 ENSDART00000009499
nsd2
nuclear receptor binding SET domain protein 2
chr2_-_43850897 0.40 ENSDART00000005449
zeb1a
zinc finger E-box binding homeobox 1a
chr21_+_17301790 0.39 ENSDART00000145057
tsc1b
TSC complex subunit 1b
chr14_+_45350008 0.38 ENSDART00000025749
ttc9c
tetratricopeptide repeat domain 9C
chr16_+_53519048 0.38 ENSDART00000124691
smpd5
sphingomyelin phosphodiesterase 5
chr15_-_19334448 0.36 ENSDART00000062576
thyn1
thymocyte nuclear protein 1
chr24_+_19415124 0.36 ENSDART00000186931
sulf1
sulfatase 1
chr7_-_50764714 0.36 ENSDART00000110283
iqgap1
IQ motif containing GTPase activating protein 1
chr6_-_3998199 0.35 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr5_-_51998708 0.35 ENSDART00000097194
serinc5
serine incorporator 5
chr25_+_4855549 0.35 ENSDART00000163839
ap4e1
adaptor-related protein complex 4, epsilon 1 subunit
chr19_-_7441948 0.34 ENSDART00000003544
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr3_+_9588705 0.34 ENSDART00000172543
ENSDART00000104875
trap1
TNF receptor-associated protein 1
chr5_-_30145939 0.34 ENSDART00000086795
zbtb44
zinc finger and BTB domain containing 44
chr15_-_33304133 0.34 ENSDART00000186092
nbeab
neurobeachin b
chr8_+_18010978 0.34 ENSDART00000039887
ENSDART00000144532
ssbp3b
single stranded DNA binding protein 3b
chr16_+_26747766 0.33 ENSDART00000183257
rad54b
RAD54 homolog B (S. cerevisiae)
chr20_+_33994580 0.33 ENSDART00000061729
si:dkey-97o5.1
si:dkey-97o5.1
chr9_-_52386733 0.33 ENSDART00000171721
dap1b
death associated protein 1b
chr3_+_60828813 0.32 ENSDART00000128260
CABZ01087514.1

chr16_-_25400257 0.32 ENSDART00000040756
zgc:136493
zgc:136493
chr16_-_44878245 0.32 ENSDART00000154391
ENSDART00000154925
ENSDART00000154697
arhgap33
Rho GTPase activating protein 33
chr21_-_3606539 0.32 ENSDART00000062418
dym
dymeclin
chr5_-_17876709 0.31 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr21_-_28640316 0.29 ENSDART00000128237
nrg2a
neuregulin 2a
chr9_-_12574473 0.29 ENSDART00000191372
ENSDART00000193667
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr22_+_2533514 0.28 ENSDART00000147967
si:ch73-92e7.4
si:ch73-92e7.4
chr11_+_23933016 0.28 ENSDART00000000486
cntn2
contactin 2
chr16_-_31351419 0.28 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr18_+_41527877 0.27 ENSDART00000146972
selenot1b
selenoprotein T, 1b
chr6_-_18531760 0.27 ENSDART00000167167
utp6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr22_+_18319666 0.26 ENSDART00000033103
gatad2ab
GATA zinc finger domain containing 2Ab
chr7_-_26049282 0.26 ENSDART00000136389
ENSDART00000101124
rnaseka
ribonuclease, RNase K a
chr7_+_40094081 0.25 ENSDART00000186054
si:ch73-174h16.4
si:ch73-174h16.4
chr8_-_18010735 0.25 ENSDART00000125014
acot11b
acyl-CoA thioesterase 11b
chr1_-_59567685 0.24 ENSDART00000159144
ENSDART00000182913
zmp:0000001082
zmp:0000001082
chr6_+_55819038 0.24 ENSDART00000108786
si:ch211-81n22.1
si:ch211-81n22.1
chr1_+_19708508 0.24 ENSDART00000054581
ENSDART00000131206
march1
membrane-associated ring finger (C3HC4) 1
chr20_+_41801913 0.23 ENSDART00000139805
mcm9
minichromosome maintenance 9 homologous recombination repair factor
chr5_-_62940851 0.23 ENSDART00000137052
specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr2_+_24317465 0.23 ENSDART00000139339
ENSDART00000136284
mrpl34
mitochondrial ribosomal protein L34
chr3_+_52078798 0.22 ENSDART00000156882
si:dkey-88e12.3
si:dkey-88e12.3
chr3_-_26341959 0.22 ENSDART00000169344
ENSDART00000142878
ENSDART00000087196
zgc:153240
zgc:153240
chr7_+_30240791 0.22 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr1_-_45616242 0.22 ENSDART00000150066
atf7ip
activating transcription factor 7 interacting protein
chr7_-_36358303 0.22 ENSDART00000130028
fto
fat mass and obesity associated
chr25_-_35127617 0.22 ENSDART00000125128
hist1h2a4
histone cluster 1 H2A family member 4
chr24_-_25030173 0.21 ENSDART00000126395
ENSDART00000019350
nup58
nucleoporin 58
chr7_+_32021669 0.21 ENSDART00000173976
mettl15
methyltransferase like 15
chr18_+_21113216 0.21 ENSDART00000060191
kmt5b
lysine methyltransferase 5B
chr5_-_68795063 0.21 ENSDART00000016307
her1
hairy-related 1
chr6_-_46560207 0.21 ENSDART00000187607
kcnb1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr2_-_37797577 0.20 ENSDART00000110781
nfatc4
nuclear factor of activated T cells 4
chr7_-_36358735 0.20 ENSDART00000188392
fto
fat mass and obesity associated
chr7_+_32021982 0.20 ENSDART00000173848
mettl15
methyltransferase like 15
chr4_-_12781182 0.20 ENSDART00000058020
helb
helicase (DNA) B
chr22_-_10440688 0.20 ENSDART00000111962
nol8
nucleolar protein 8
chr23_+_42482137 0.19 ENSDART00000160199
cyp2aa3
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr17_+_24111392 0.19 ENSDART00000180123
ENSDART00000182787
ENSDART00000189752
ENSDART00000184940
ENSDART00000185363
ENSDART00000064067
ehbp1
EH domain binding protein 1
chr25_+_28158352 0.18 ENSDART00000151854
cadps2
Ca++-dependent secretion activator 2
chr7_-_57949117 0.17 ENSDART00000138803
ank2b
ankyrin 2b, neuronal
chr16_-_21692024 0.16 ENSDART00000123597
si:ch211-154o6.2
si:ch211-154o6.2
chr5_-_31035198 0.16 ENSDART00000086534
cyb5d2
cytochrome b5 domain containing 2
chr24_+_32472155 0.15 ENSDART00000098859
neurod6a
neuronal differentiation 6a
chr7_+_26006819 0.15 ENSDART00000112908
pelp1
proline, glutamate and leucine rich protein 1
chr4_-_31666343 0.14 ENSDART00000190758
ENSDART00000192721
si:dkey-16p6.1
si:dkey-16p6.1
chr7_-_30174882 0.14 ENSDART00000110409
frmd5
FERM domain containing 5
chr13_+_48358467 0.14 ENSDART00000171080
ENSDART00000162531
msh6
mutS homolog 6 (E. coli)
chr19_-_7690975 0.13 ENSDART00000151384
si:dkey-204a24.10
si:dkey-204a24.10
chr12_-_4424424 0.12 ENSDART00000152314
si:ch211-173d10.1
si:ch211-173d10.1
chr5_+_56119975 0.12 ENSDART00000083137
mrm1
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr8_-_36125849 0.12 ENSDART00000159581
CT583723.1

chr20_-_33583779 0.12 ENSDART00000097823
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr5_+_3118231 0.12 ENSDART00000179809
supt4h1
SPT4 homolog, DSIF elongation factor subunit
chr17_-_2834764 0.12 ENSDART00000024027
bdkrb1
bradykinin receptor B1
chr9_-_3834686 0.11 ENSDART00000141492
myo3b
myosin IIIB
chr22_-_34995333 0.11 ENSDART00000110900
kcnip2
Kv channel interacting protein 2
chr6_+_39279831 0.10 ENSDART00000155088
ankrd33ab
ankyrin repeat domain 33Ab
chr9_-_16877456 0.10 ENSDART00000161105
ENSDART00000160869
fbxl3a
F-box and leucine-rich repeat protein 3a
chr21_+_26539157 0.09 ENSDART00000021121
stx5al
syntaxin 5A, like
chr1_+_29515160 0.09 ENSDART00000152226
si:dkey-228l14.1
si:dkey-228l14.1
chr10_+_38526496 0.09 ENSDART00000144329
acer3
alkaline ceramidase 3
chr20_+_22067337 0.09 ENSDART00000152636
clocka
clock circadian regulator a
chr11_-_7147540 0.09 ENSDART00000143942
bmp7a
bone morphogenetic protein 7a
chr10_-_36244864 0.08 ENSDART00000123748
or109-1
odorant receptor, family D, subfamily 109, member 1
chr6_+_58549080 0.08 ENSDART00000180117
stmn3
stathmin-like 3
chr8_+_47897734 0.08 ENSDART00000140266
mfn2
mitofusin 2
chr16_-_29405009 0.08 ENSDART00000149289
tlr18
toll-like receptor 18
chr1_+_56972616 0.08 ENSDART00000152812
si:ch211-1f22.11
si:ch211-1f22.11
chr23_-_1017428 0.08 ENSDART00000110588
ENSDART00000183158
cdh26.1
cadherin 26, tandem duplicate 1
chr15_-_46736432 0.08 ENSDART00000124567
ilkap
integrin-linked kinase-associated serine/threonine phosphatase
chr3_-_34051363 0.07 ENSDART00000151768
ighv3-2
immunoglobulin heavy variable 3-2
chr22_+_2524615 0.07 ENSDART00000134277
znf1003
zinc finger protein 1003
chr4_+_38547203 0.07 ENSDART00000171349
si:ch211-209n20.1
si:ch211-209n20.1
chr2_+_23130389 0.07 ENSDART00000142834
si:dkey-218h11.6
si:dkey-218h11.6
chr19_-_19599372 0.07 ENSDART00000160002
ENSDART00000171664
tax1bp1a
Tax1 (human T-cell leukemia virus type I) binding protein 1a
chr1_-_11606903 0.07 ENSDART00000136093
si:dkey-26i13.6
si:dkey-26i13.6
chr15_-_31357634 0.07 ENSDART00000127485
or111-2
odorant receptor, family D, subfamily 111, member 2
chr7_-_32021853 0.07 ENSDART00000134521
kif18a
kinesin family member 18A
chr8_-_53044089 0.06 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr7_+_3597413 0.06 ENSDART00000064281
si:dkey-192d15.2
si:dkey-192d15.2
chr22_-_23590069 0.06 ENSDART00000172067
f13b
coagulation factor XIII, B polypeptide
chr22_+_18319230 0.06 ENSDART00000184747
ENSDART00000184649
gatad2ab
GATA zinc finger domain containing 2Ab
chr9_+_30211038 0.06 ENSDART00000190847
senp7a
SUMO1/sentrin specific peptidase 7a
chr11_-_21404044 0.06 ENSDART00000080116
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr5_+_29652198 0.06 ENSDART00000184083
tsc1a
TSC complex subunit 1a
chr21_-_43949208 0.06 ENSDART00000150983
camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr1_-_11607062 0.06 ENSDART00000158253
si:dkey-26i13.6
si:dkey-26i13.6
chr21_-_37973081 0.05 ENSDART00000136569
ripply1
ripply transcriptional repressor 1
chr4_+_32772213 0.05 ENSDART00000137958
ENSDART00000125835
si:dkey-16p6.1
si:dkey-16p6.1
chr17_+_28670132 0.05 ENSDART00000076344
ENSDART00000164981
ENSDART00000182851
hectd1
HECT domain containing 1
chr21_+_17541634 0.05 ENSDART00000191700
ENSDART00000163238
stom
stomatin
chr8_+_28695914 0.05 ENSDART00000033386
ocstamp
osteoclast stimulatory transmembrane protein
chr3_+_43460696 0.04 ENSDART00000164581
galr2b
galanin receptor 2b
chr10_-_7472323 0.04 ENSDART00000163702
ENSDART00000167054
ENSDART00000167706
nrg1
neuregulin 1
chr23_+_17878969 0.04 ENSDART00000154934
ENSDART00000154140
ENSDART00000156331
si:ch73-390p7.2
si:ch73-390p7.2
chr14_-_17306261 0.04 ENSDART00000191747
jakmip1
janus kinase and microtubule interacting protein 1
chr15_-_8191992 0.04 ENSDART00000155381
ENSDART00000190714
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr8_-_53044300 0.04 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr15_-_8177919 0.03 ENSDART00000101463
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr14_-_2221877 0.03 ENSDART00000106704
pcdh2ab1
protocadherin 2 alpha b 1
chr7_-_13362590 0.03 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr8_-_49201258 0.03 ENSDART00000114584
ENSDART00000142172
zgc:171501
zgc:171501
chr4_-_53047883 0.03 ENSDART00000157496
si:dkey-201g16.5
si:dkey-201g16.5
chr24_-_36723116 0.03 ENSDART00000088204
si:ch73-334d15.1
si:ch73-334d15.1
chr16_+_29586004 0.03 ENSDART00000149520
mcl1b
MCL1, BCL2 family apoptosis regulator b
chr7_+_4971938 0.03 ENSDART00000172889
ENSDART00000145389
si:dkey-81n2.2
si:dkey-81n2.2
chr17_-_5610514 0.03 ENSDART00000004043
enpp4
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr8_-_8426504 0.03 ENSDART00000191686
ENSDART00000181523
cdk16
cyclin-dependent kinase 16
chr12_-_44122412 0.02 ENSDART00000169094
si:ch73-329n5.3
si:ch73-329n5.3
chr10_+_40700311 0.02 ENSDART00000157650
ENSDART00000138342
taar19n
trace amine associated receptor 19n
chr1_-_11616142 0.02 ENSDART00000131668
si:dkey-26i13.5
si:dkey-26i13.5
chr3_+_23710839 0.02 ENSDART00000151584
hoxb4a
homeobox B4a
chr20_+_45853154 0.02 ENSDART00000181109
AL929237.4

chr14_-_17305657 0.02 ENSDART00000168853
jakmip1
janus kinase and microtubule interacting protein 1
chr15_-_8191841 0.02 ENSDART00000156663
bach1a
BTB and CNC homology 1, basic leucine zipper transcription factor 1 a
chr16_+_24972826 0.02 ENSDART00000063115
fpr1
formyl peptide receptor 1
chr4_-_77377596 0.02 ENSDART00000186068
slco1e1
solute carrier organic anion transporter family, member 1E1
chr19_+_3840955 0.01 ENSDART00000172305
lsm10
LSM10, U7 small nuclear RNA associated
chr9_-_3149896 0.01 ENSDART00000020861
pdk1
pyruvate dehydrogenase kinase, isozyme 1
chr13_-_29420885 0.01 ENSDART00000024225
chata
choline O-acetyltransferase a
chr16_-_29480335 0.01 ENSDART00000148930
lingo4b
leucine rich repeat and Ig domain containing 4b
chr18_-_20560007 0.01 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
si:ch211-238n5.4
chr5_-_56513825 0.01 ENSDART00000024207
tbx2a
T-box 2a
chr15_-_31406093 0.01 ENSDART00000123444
or111-8
odorant receptor, family D, subfamily 111, member 8
chr4_-_46946643 0.01 ENSDART00000180392
ENSDART00000184563
si:dkey-16p6.1
si:dkey-16p6.1
chr1_+_8314826 0.01 ENSDART00000160440
cacna1hb
calcium channel, voltage-dependent, T type, alpha 1H subunit b
chr3_+_52684556 0.01 ENSDART00000139037
pgls
6-phosphogluconolactonase
chr17_-_50472864 0.01 ENSDART00000161066
ENSDART00000156963
si:ch211-235i11.3
si:ch211-235i11.3
chr5_+_27897504 0.00 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr14_-_17305849 0.00 ENSDART00000160971
jakmip1
janus kinase and microtubule interacting protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3b+foxo6a+foxo6b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0000212 meiotic spindle organization(GO:0000212)
0.3 1.0 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.4 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.4 GO:0042245 RNA repair(GO:0042245)
0.1 0.7 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.8 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:0010867 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.3 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 1.0 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.4 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773) regulation of isotype switching(GO:0045191) positive regulation of isotype switching(GO:0045830)
0.1 1.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.5 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.3 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.3 GO:0045454 cell redox homeostasis(GO:0045454)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.6 GO:0032300 mismatch repair complex(GO:0032300)
0.0 1.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 1.0 GO:0005795 Golgi stack(GO:0005795)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034618 arginine binding(GO:0034618)
0.1 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0035516 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.3 GO:0070513 death domain binding(GO:0070513)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0032405 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 1.0 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII