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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for gata1a+gata2b
Z-value: 0.18
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Transcription factors associated with gata1a+gata2b
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
gata2b
|
ENSDARG00000009094 | GATA binding protein 2b |
|
gata1a
|
ENSDARG00000013477 | GATA binding protein 1a |
|
gata1a
|
ENSDARG00000117116 | GATA binding protein 1a |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| gata1a | dr11_v1_chr11_-_25418856_25418856 | -0.81 | 4.2e-05 | Click! |
| gata2b | dr11_v1_chr6_+_40794015_40794015 | 0.45 | 6.0e-02 | Click! |
Activity profile of gata1a+gata2b motif
Sorted Z-values of gata1a+gata2b motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_35532937 | 0.33 |
ENSDART00000193209
|
ctps1b
|
CTP synthase 1b |
| chr22_+_21398508 | 0.33 |
ENSDART00000089408
ENSDART00000186091 |
shdb
|
Src homology 2 domain containing transforming protein D, b |
| chr18_+_3169579 | 0.26 |
ENSDART00000164724
ENSDART00000186340 ENSDART00000181247 ENSDART00000168056 |
pak1
|
p21 protein (Cdc42/Rac)-activated kinase 1 |
| chr10_+_42589391 | 0.21 |
ENSDART00000067689
ENSDART00000075259 |
fgfr1b
|
fibroblast growth factor receptor 1b |
| chr11_-_40457325 | 0.19 |
ENSDART00000128442
|
tnfrsf1b
|
tumor necrosis factor receptor superfamily, member 1B |
| chr8_-_6825588 | 0.18 |
ENSDART00000135834
|
dock5
|
dedicator of cytokinesis 5 |
| chr10_-_31175744 | 0.17 |
ENSDART00000191728
|
pknox2
|
pbx/knotted 1 homeobox 2 |
| chr4_-_2380173 | 0.12 |
ENSDART00000177727
|
nap1l1
|
nucleosome assembly protein 1-like 1 |
| chr19_-_32710922 | 0.07 |
ENSDART00000004034
|
hpca
|
hippocalcin |
| chr22_-_16270462 | 0.07 |
ENSDART00000105681
|
cdc14ab
|
cell division cycle 14Ab |
| chr6_-_49159207 | 0.07 |
ENSDART00000041942
|
tspan2a
|
tetraspanin 2a |
| chr5_+_18047111 | 0.06 |
ENSDART00000132164
|
hira
|
histone cell cycle regulator a |
| chr22_+_15507218 | 0.03 |
ENSDART00000125450
|
gpc1a
|
glypican 1a |
| chr5_-_7199998 | 0.02 |
ENSDART00000167316
|
CABZ01087502.1
|
|
| chr21_+_43561650 | 0.02 |
ENSDART00000085071
|
gpr185a
|
G protein-coupled receptor 185 a |
| chr14_+_918287 | 0.01 |
ENSDART00000167066
|
CU462913.1
|
|
| chr15_-_16704417 | 0.00 |
ENSDART00000155163
|
caln1
|
calneuron 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of gata1a+gata2b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.0 | 0.3 | GO:0003232 | bulbus arteriosus development(GO:0003232) |
| 0.0 | 0.2 | GO:1901534 | positive regulation of hematopoietic progenitor cell differentiation(GO:1901534) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0097268 | cytoophidium(GO:0097268) |
| 0.0 | 0.1 | GO:1902636 | kinociliary basal body(GO:1902636) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.1 | 0.3 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.2 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.3 | PID S1P S1P2 PATHWAY | S1P2 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |