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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for gfi1aa+gfi1ab

Z-value: 0.81

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Transcription factors associated with gfi1aa+gfi1ab

Gene Symbol Gene ID Gene Info
gfi1aa
ENSDARG00000020746 growth factor independent 1A transcription repressor a
gfi1ab
ENSDARG00000044457 growth factor independent 1A transcription repressor b
gfi1ab
ENSDARG00000114140 growth factor independent 1A transcription repressor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gfi1aadr11_v1_chr2_+_10766744_10766744-0.644.0e-03Click!
gfi1abdr11_v1_chr6_-_29007493_29007493-0.571.4e-02Click!

Activity profile of gfi1aa+gfi1ab motif

Sorted Z-values of gfi1aa+gfi1ab motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_35252761 1.84 ENSDART00000051278
tnpo1
transportin 1
chr11_-_10456387 1.78 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr14_-_49110280 1.70 ENSDART00000023654
sfxn1
sideroflexin 1
chr11_-_10456553 1.69 ENSDART00000169509
ENSDART00000185574
ENSDART00000188276
ect2
epithelial cell transforming 2
chr6_-_53143667 1.63 ENSDART00000079694
gnai2b
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b
chr20_+_26940178 1.60 ENSDART00000190888
cdca4
cell division cycle associated 4
chr2_-_9915814 1.54 ENSDART00000091644
ENSDART00000177556
abi1b
abl-interactor 1b
chr2_+_23007675 1.52 ENSDART00000163649
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr7_-_26603743 1.50 ENSDART00000099003
plscr3b
phospholipid scramblase 3b
chr5_+_57328535 1.43 ENSDART00000149646
slc31a1
solute carrier family 31 (copper transporter), member 1
chr10_-_15849027 1.41 ENSDART00000184682
tjp2a
tight junction protein 2a (zona occludens 2)
chr3_+_54168007 1.38 ENSDART00000109894
olfm2a
olfactomedin 2a
chr3_-_36440705 1.37 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr21_+_13233377 1.33 ENSDART00000142569
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr9_+_54984900 1.33 ENSDART00000191622
mospd2
motile sperm domain containing 2
chr20_+_27749133 1.32 ENSDART00000089013
vrtn
vertebrae development associated
chr7_-_60351876 1.31 ENSDART00000098563
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr13_+_15816573 1.30 ENSDART00000137061
klc1a
kinesin light chain 1a
chr20_+_26939742 1.29 ENSDART00000138369
ENSDART00000062061
ENSDART00000152992
cdca4
cell division cycle associated 4
chr6_-_39518489 1.25 ENSDART00000185446
atf1
activating transcription factor 1
chr16_-_51151993 1.25 ENSDART00000156255
ago1
argonaute RISC catalytic component 1
chr7_-_60351537 1.24 ENSDART00000159875
plcb3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr18_+_35130416 1.24 ENSDART00000151595
si:ch211-195m9.3
si:ch211-195m9.3
chr25_+_36292465 1.21 ENSDART00000152649
bmb
brambleberry
chr5_-_54714525 1.20 ENSDART00000150138
ENSDART00000150070
ccnb1
cyclin B1
chr5_-_54714789 1.20 ENSDART00000063357
ccnb1
cyclin B1
chr14_-_7245971 1.20 ENSDART00000108796
stox2b
storkhead box 2b
chr24_+_39137001 1.19 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr25_-_17918536 1.18 ENSDART00000148660
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr6_-_53326421 1.17 ENSDART00000191740
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr2_+_9821757 1.17 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr25_+_7532811 1.16 ENSDART00000161593
ptdss2
phosphatidylserine synthase 2
chr10_+_41939963 1.14 ENSDART00000126248
tmem120b
transmembrane protein 120B
chr21_-_9466201 1.14 ENSDART00000167211
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr16_+_39159752 1.14 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr7_+_69187585 1.14 ENSDART00000160499
ENSDART00000166258
marveld3
MARVEL domain containing 3
chr16_-_54187374 1.11 ENSDART00000186989
ENSDART00000190113
LO017872.1

chr4_+_9279784 1.10 ENSDART00000014897
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr8_+_16758304 1.09 ENSDART00000133514
elovl7a
ELOVL fatty acid elongase 7a
chr24_+_12835935 1.09 ENSDART00000114762
nanog
nanog homeobox
chr3_-_54607166 1.09 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr6_-_49537646 1.09 ENSDART00000180438
FO704848.1

chr24_-_26622423 1.08 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr13_-_18691041 1.07 ENSDART00000057867
sfxn3
sideroflexin 3
chr6_+_36821621 1.07 ENSDART00000104157
tmem45a
transmembrane protein 45a
chr21_+_38033226 1.06 ENSDART00000085728
klf8
Kruppel-like factor 8
chr11_+_11120532 1.05 ENSDART00000026135
ENSDART00000189872
ly75
lymphocyte antigen 75
chr4_-_12477224 1.03 ENSDART00000027756
ENSDART00000182706
ENSDART00000127150
arhgef39
Rho guanine nucleotide exchange factor (GEF) 39
chr24_+_19518303 1.02 ENSDART00000027022
ENSDART00000056080
sulf1
sulfatase 1
chr13_-_45022527 1.02 ENSDART00000159021
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr20_-_25645150 1.01 ENSDART00000063137
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr15_+_30126971 1.00 ENSDART00000100214
nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr9_-_34500197 0.99 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr18_+_22793465 0.99 ENSDART00000149685
gnao1a
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr10_+_38663917 0.98 ENSDART00000170182
acat1
acetyl-CoA acetyltransferase 1
chr4_-_1720648 0.97 ENSDART00000103484
gas2l3
growth arrest-specific 2 like 3
chr1_-_40519340 0.97 ENSDART00000114659
maml3
mastermind-like transcriptional coactivator 3
chr24_+_19518570 0.97 ENSDART00000056081
sulf1
sulfatase 1
chr16_+_45337663 0.97 ENSDART00000147343
ENSDART00000185731
dnase2
deoxyribonuclease II, lysosomal
chr16_-_34285106 0.97 ENSDART00000044235
phactr4b
phosphatase and actin regulator 4b
chr17_+_14965570 0.96 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr17_-_22573311 0.96 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exo1
exonuclease 1
chr6_+_40563848 0.96 ENSDART00000154766
si:ch73-15b2.5
si:ch73-15b2.5
chr20_-_31427390 0.95 ENSDART00000007735
ust
uronyl-2-sulfotransferase
chr4_-_20177868 0.95 ENSDART00000003621
sinup
siaz-interacting nuclear protein
chr16_+_30117798 0.94 ENSDART00000135723
ENSDART00000000198
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr8_-_7308373 0.94 ENSDART00000132009
ENSDART00000145345
grip2a
glutamate receptor interacting protein 2a
chr8_+_10869183 0.94 ENSDART00000188111
brpf3b
bromodomain and PHD finger containing, 3b
chr22_-_10541712 0.93 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr5_-_25572151 0.92 ENSDART00000144995
si:dkey-229d2.4
si:dkey-229d2.4
chr14_-_33278084 0.92 ENSDART00000132850
stard14
START domain containing 14
chr11_-_30508843 0.91 ENSDART00000101667
ENSDART00000179930
map4k3a
mitogen-activated protein kinase kinase kinase kinase 3a
chr14_-_33277743 0.91 ENSDART00000048130
stard14
START domain containing 14
chr12_-_28794957 0.90 ENSDART00000020667
osbpl7
oxysterol binding protein-like 7
chr16_+_43077909 0.90 ENSDART00000014140
rundc3b
RUN domain containing 3b
chr13_+_22712406 0.89 ENSDART00000132847
si:ch211-134m17.9
si:ch211-134m17.9
chr13_-_45022301 0.89 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr17_-_31483469 0.87 ENSDART00000062907
ENSDART00000061547
ltk
leukocyte receptor tyrosine kinase
chr3_+_26244353 0.87 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr11_+_13424116 0.86 ENSDART00000125563
homer3b
homer scaffolding protein 3b
chr4_-_20235904 0.86 ENSDART00000146621
ENSDART00000193655
stk38l
serine/threonine kinase 38 like
chr23_+_1216215 0.86 ENSDART00000165957
utrn
utrophin
chr25_-_17918810 0.86 ENSDART00000023959
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr6_+_40523370 0.86 ENSDART00000033819
prkcda
protein kinase C, delta a
chr12_+_16087077 0.86 ENSDART00000141898
znf281b
zinc finger protein 281b
chr12_+_10706772 0.86 ENSDART00000158227
top2a
DNA topoisomerase II alpha
chr3_+_32661765 0.85 ENSDART00000165562
si:dkey-16l2.16
si:dkey-16l2.16
chr20_-_13625588 0.85 ENSDART00000078893
sytl3
synaptotagmin-like 3
chr13_-_48431766 0.85 ENSDART00000159688
ENSDART00000171765
fbxo11a
F-box protein 11a
chr13_+_11829072 0.83 ENSDART00000079356
ENSDART00000170160
sufu
suppressor of fused homolog (Drosophila)
chr11_+_19370717 0.83 ENSDART00000165906
prickle2b
prickle homolog 2b
chr17_-_8638713 0.82 ENSDART00000148971
ctbp2a
C-terminal binding protein 2a
chr15_-_17025212 0.82 ENSDART00000014465
hip1
huntingtin interacting protein 1
chr5_-_31773208 0.82 ENSDART00000137556
ENSDART00000122066
fam102ab
family with sequence similarity 102, member Ab
chr13_+_47710434 0.81 ENSDART00000188724
TMEM87B
transmembrane protein 87B
chr20_+_23625387 0.81 ENSDART00000147945
ENSDART00000150497
palld
palladin, cytoskeletal associated protein
chr23_-_26228077 0.81 ENSDART00000162423
BX927204.1

chr9_+_33340311 0.79 ENSDART00000140064
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr6_+_38626926 0.78 ENSDART00000190339
atp10a
ATPase phospholipid transporting 10A
chr18_+_22217489 0.78 ENSDART00000165464
ripor1
RHO family interacting cell polarization regulator 1
chr22_-_10541372 0.77 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr18_-_38270430 0.77 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr21_-_929448 0.76 ENSDART00000133976
txnl1
thioredoxin-like 1
chr12_-_48188928 0.76 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr15_-_9294929 0.76 ENSDART00000155717
si:ch211-261a10.5
si:ch211-261a10.5
chr5_-_54712159 0.76 ENSDART00000149207
ccnb1
cyclin B1
chr19_+_791538 0.75 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr15_-_31265375 0.75 ENSDART00000086592
vezf1b
vascular endothelial zinc finger 1b
chr2_+_9822319 0.75 ENSDART00000144078
ENSDART00000144371
anxa13l
annexin A13, like
chr3_+_26294161 0.75 ENSDART00000157648
ENSDART00000172337
rhot1a
ras homolog family member T1a
chr13_-_24263682 0.74 ENSDART00000176800
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr20_-_51814080 0.74 ENSDART00000041476
mia3
melanoma inhibitory activity family, member 3
chr19_+_37120491 0.74 ENSDART00000032341
pef1
penta-EF-hand domain containing 1
chr5_-_45958838 0.74 ENSDART00000135072
poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr3_-_33113879 0.74 ENSDART00000044677
rarab
retinoic acid receptor, alpha b
chr22_+_30137374 0.74 ENSDART00000187808
add3a
adducin 3 (gamma) a
chr23_+_9268083 0.73 ENSDART00000055054
acss2
acyl-CoA synthetase short chain family member 2
chr20_-_28842524 0.73 ENSDART00000046035
ENSDART00000139843
ENSDART00000129858
ENSDART00000137425
ENSDART00000135720
max
myc associated factor X
chr8_+_3649036 0.73 ENSDART00000033152
rab35b
RAB35, member RAS oncogene family b
chr24_-_27256673 0.73 ENSDART00000181182
zmynd11
zinc finger, MYND-type containing 11
chr3_+_29082267 0.73 ENSDART00000145615
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr6_+_27090800 0.73 ENSDART00000121558
atg4b
autophagy related 4B, cysteine peptidase
chr19_-_27448606 0.73 ENSDART00000079251
vars2
valyl-tRNA synthetase 2, mitochondrial (putative)
chr3_-_34561624 0.72 ENSDART00000129313
sept9a
septin 9a
chr5_-_69180227 0.72 ENSDART00000154816
zgc:171967
zgc:171967
chr17_-_37795865 0.72 ENSDART00000025853
zfp36l1a
zinc finger protein 36, C3H type-like 1a
chr11_+_14104417 0.72 ENSDART00000059752
ENSDART00000186575
med16
mediator complex subunit 16
chr23_-_31645760 0.72 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr22_-_506522 0.71 ENSDART00000106645
ENSDART00000067637
dstyk
dual serine/threonine and tyrosine protein kinase
chr15_-_17024779 0.70 ENSDART00000154719
hip1
huntingtin interacting protein 1
chr9_+_22634073 0.70 ENSDART00000181822
etv5a
ets variant 5a
chr12_-_33817804 0.70 ENSDART00000191385
twnk
twinkle mtDNA helicase
chr2_-_21786826 0.69 ENSDART00000016208
chd7
chromodomain helicase DNA binding protein 7
chr13_-_42724645 0.69 ENSDART00000046066
capn1a
calpain 1, (mu/I) large subunit a
chr9_+_28232522 0.69 ENSDART00000031761
fzd5
frizzled class receptor 5
chr22_-_11493236 0.69 ENSDART00000002691
tspan7b
tetraspanin 7b
chr5_-_69934558 0.68 ENSDART00000124954
ugt2a4
UDP glucuronosyltransferase 2 family, polypeptide A4
chr23_+_27778670 0.68 ENSDART00000053863
kmt2d
lysine (K)-specific methyltransferase 2D
chr7_+_56735195 0.68 ENSDART00000082830
KIAA0895L
KIAA0895 like
chr6_-_12912606 0.68 ENSDART00000164640
ical1
islet cell autoantigen 1-like
chr9_+_54984537 0.67 ENSDART00000029528
mospd2
motile sperm domain containing 2
chr8_-_16674584 0.67 ENSDART00000100727
osbpl9
oxysterol binding protein-like 9
chr3_-_26244256 0.67 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr8_-_36618073 0.67 ENSDART00000047912
gpkow
G patch domain and KOW motifs
chr24_-_21973365 0.67 ENSDART00000081204
ENSDART00000030592
acot9.1
acyl-CoA thioesterase 9, tandem duplicate 1
chr8_+_54081819 0.67 ENSDART00000005857
ENSDART00000161795
prickle2a
prickle homolog 2a
chr6_+_50393047 0.66 ENSDART00000055502
ENSDART00000055511
ergic3
ERGIC and golgi 3
chr12_-_8958353 0.65 ENSDART00000041728
cyp26a1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr18_+_20047374 0.65 ENSDART00000146957
uacaa
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr1_-_46650022 0.65 ENSDART00000148759
ENSDART00000053222
rcbtb1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr15_-_17169935 0.64 ENSDART00000110111
cul5a
cullin 5a
chr20_+_25645459 0.63 ENSDART00000143555
ENSDART00000036350
aasdh
aminoadipate-semialdehyde dehydrogenase
chr19_-_8798178 0.63 ENSDART00000188232
cers2a
ceramide synthase 2a
chr5_+_31959954 0.63 ENSDART00000142826
myo1hb
myosin IHb
chr9_-_22057658 0.63 ENSDART00000101944
crygmxl1
crystallin, gamma MX, like 1
chr17_+_30591287 0.62 ENSDART00000154243
si:dkey-190l8.2
si:dkey-190l8.2
chr2_+_36620011 0.62 ENSDART00000177428
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr15_+_17100697 0.62 ENSDART00000183565
ENSDART00000123197
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr18_+_27571448 0.62 ENSDART00000147886
cd82b
CD82 molecule b
chr3_-_5228137 0.62 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr22_+_22437561 0.62 ENSDART00000089622
kif14
kinesin family member 14
chr24_+_39277043 0.61 ENSDART00000165458
MPRIP
si:ch73-103b11.2
chr24_-_21973163 0.61 ENSDART00000131406
acot9.1
acyl-CoA thioesterase 9, tandem duplicate 1
chr16_-_31284922 0.61 ENSDART00000142638
mroh1
maestro heat-like repeat family member 1
chr7_+_66884570 0.61 ENSDART00000082664
sbf2
SET binding factor 2
chr18_-_20466061 0.61 ENSDART00000060311
paqr5a
progestin and adipoQ receptor family member Va
chr11_-_43473824 0.61 ENSDART00000179561
tmem63bb
transmembrane protein 63Bb
chr1_+_10003193 0.60 ENSDART00000162675
trim2b
tripartite motif containing 2b
chr3_-_58165254 0.60 ENSDART00000093031
snu13a
SNU13 homolog, small nuclear ribonucleoprotein a (U4/U6.U5)
chr22_+_25088999 0.59 ENSDART00000158225
rrbp1b
ribosome binding protein 1b
chr15_-_41310340 0.59 ENSDART00000192112
si:dkey-75b17.1
si:dkey-75b17.1
chr16_+_26601364 0.58 ENSDART00000087537
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr6_-_14040136 0.58 ENSDART00000065361
ENSDART00000179765
etv5b
ets variant 5b
chr8_+_16738282 0.58 ENSDART00000134265
ENSDART00000100698
ercc8
excision repair cross-complementation group 8
chr11_+_25693395 0.58 ENSDART00000110224
mon1bb
MON1 secretory trafficking family member Bb
chr20_-_25902141 0.58 ENSDART00000142611
ENSDART00000024821
elmsan1a
ELM2 and Myb/SANT-like domain containing 1a
chr17_+_19630068 0.57 ENSDART00000182619
rgs7a
regulator of G protein signaling 7a
chr21_-_27619701 0.57 ENSDART00000133441
ENSDART00000180100
pcnxl3
pecanex-like 3 (Drosophila)
chr8_-_25566347 0.57 ENSDART00000138289
ENSDART00000078022
prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr7_+_34236238 0.57 ENSDART00000052474
tipin
timeless interacting protein
chr12_+_32368574 0.57 ENSDART00000086389
ANKFN1
si:ch211-277e21.2
chr19_+_27448625 0.57 ENSDART00000052352
ppp1r11
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr13_+_43650632 0.57 ENSDART00000141024
zfyve21
zinc finger, FYVE domain containing 21
chr10_+_7719796 0.57 ENSDART00000191795
ggcx
gamma-glutamyl carboxylase
chr6_-_46053300 0.57 ENSDART00000169722
ca16b
carbonic anhydrase XVI b
chr16_+_26439518 0.57 ENSDART00000041787
trim35-28
tripartite motif containing 35-28
chr2_+_31308587 0.57 ENSDART00000027090
clul1
clusterin-like 1 (retinal)
chr18_+_16722129 0.56 ENSDART00000146163
eif4g2b
eukaryotic translation initiation factor 4, gamma 2b
chr7_-_48396193 0.56 ENSDART00000083555
sin3ab
SIN3 transcription regulator family member Ab
chr2_-_40889465 0.56 ENSDART00000192631
ENSDART00000180824
uggt1
UDP-glucose glycoprotein glucosyltransferase 1
chr23_+_19594608 0.56 ENSDART00000134865
slmapb
sarcolemma associated protein b
chr11_+_14333441 0.56 ENSDART00000171969
ptbp1b
polypyrimidine tract binding protein 1b
chr16_-_42770064 0.55 ENSDART00000112879
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr6_+_59642695 0.55 ENSDART00000166373
ENSDART00000161030
R3HDM2
R3H domain containing 2
chr7_+_17063761 0.54 ENSDART00000182880
htatip2
HIV-1 Tat interactive protein 2
chr3_-_1400309 0.54 ENSDART00000159893
wbp11
WW domain binding protein 11
chr18_-_25905574 0.54 ENSDART00000143899
ENSDART00000163369
sema4ba
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr18_-_38270077 0.54 ENSDART00000185546
caprin1b
cell cycle associated protein 1b
chr18_+_44703343 0.54 ENSDART00000131510
b3gnt2l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr23_-_32157865 0.54 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of gfi1aa+gfi1ab

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.4 1.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.4 3.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.3 1.7 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.3 3.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.3 1.4 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.3 1.1 GO:0060074 synapse maturation(GO:0060074)
0.2 2.0 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.2 0.7 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.2 0.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 1.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 0.8 GO:1900181 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.2 1.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 2.9 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 2.5 GO:0090279 regulation of calcium ion import(GO:0090279)
0.1 1.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.6 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 0.4 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.1 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.0 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 1.0 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.7 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.5 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031) pancreas morphogenesis(GO:0061113)
0.1 0.9 GO:0070285 pigment cell development(GO:0070285)
0.1 0.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.7 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.1 1.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.5 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.4 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.1 1.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.8 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.5 GO:1904667 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 1.3 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.6 GO:0043111 replication fork arrest(GO:0043111)
0.1 0.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.8 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.6 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.4 GO:0071674 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.3 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.7 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.3 GO:0042148 strand invasion(GO:0042148)
0.1 1.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 1.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.9 GO:0001840 neural plate development(GO:0001840)
0.1 0.7 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.7 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.1 0.7 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 1.0 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.3 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 1.1 GO:0006265 DNA topological change(GO:0006265)
0.1 0.9 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.2 GO:0039529 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 0.3 GO:2000252 negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 0.7 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 2.1 GO:0009648 photoperiodism(GO:0009648)
0.1 1.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.6 GO:0045444 fat cell differentiation(GO:0045444)
0.1 0.2 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.3 GO:0035889 otolith tethering(GO:0035889)
0.1 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.4 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.3 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.1 0.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.5 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.2 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.4 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.4 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.1 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.3 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.5 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:1903723 negative regulation of centriole elongation(GO:1903723)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.7 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 1.5 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 1.7 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 1.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.7 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.3 GO:0035475 angioblast cell migration involved in selective angioblast sprouting(GO:0035475)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 2.4 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.0 1.3 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 2.4 GO:0051170 nuclear import(GO:0051170)
0.0 0.2 GO:0048909 anterior lateral line nerve development(GO:0048909)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.5 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 2.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0006298 mismatch repair(GO:0006298)
0.0 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 1.0 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.9 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.4 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) vasodilation(GO:0042311)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 4.3 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0003315 heart rudiment formation(GO:0003315)
0.0 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.0 1.0 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.0 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 1.2 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.7 GO:0060389 pathway-restricted SMAD protein phosphorylation(GO:0060389)
0.0 0.4 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.3 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.5 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.4 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.2 GO:0048794 swim bladder development(GO:0048794)
0.0 0.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 1.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.8 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 0.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) mannosylation(GO:0097502)
0.0 0.1 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.1 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.6 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 0.3 GO:0007632 visual behavior(GO:0007632)
0.0 0.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672) regulation of chromatin assembly(GO:0010847)
0.0 1.3 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.9 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0 0.2 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.0 0.2 GO:0014855 striated muscle cell proliferation(GO:0014855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.2 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 1.5 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 1.4 GO:0043291 RAVE complex(GO:0043291)
0.2 0.7 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.2 0.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.8 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.6 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0001772 immunological synapse(GO:0001772)
0.1 1.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.5 GO:0000796 condensin complex(GO:0000796)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.4 GO:0043194 axon initial segment(GO:0043194)
0.1 3.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.2 GO:1990745 EARP complex(GO:1990745)
0.1 1.3 GO:0005921 gap junction(GO:0005921)
0.1 0.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.7 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.2 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 2.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.6 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 2.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 2.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.9 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.7 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0045495 pole plasm(GO:0045495)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.3 GO:0005938 cell cortex(GO:0005938)
0.0 0.2 GO:0046930 pore complex(GO:0046930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.3 1.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.3 1.0 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.3 1.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 1.4 GO:0031852 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.7 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.2 0.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.7 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.7 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.1 0.6 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.1 1.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.4 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 2.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 1.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.0 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 1.9 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 3.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.7 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.7 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.9 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 1.0 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 2.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 1.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.5 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 1.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.6 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.4 GO:0003916 DNA topoisomerase activity(GO:0003916) DNA topoisomerase type I activity(GO:0003917)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 3.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.2 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.7 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.9 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.9 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 4.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 1.4 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 2.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 2.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 3.0 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.6 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.3 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.8 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 3.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 1.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling