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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for gfi1b

Z-value: 0.81

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Transcription factors associated with gfi1b

Gene Symbol Gene ID Gene Info
gfi1b
ENSDARG00000079947 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gfi1bdr11_v1_chr21_-_17290941_17290941-0.302.2e-01Click!

Activity profile of gfi1b motif

Sorted Z-values of gfi1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_15937610 1.96 ENSDART00000061134
ENSDART00000154505
itpr2
inositol 1,4,5-trisphosphate receptor, type 2
chr21_+_7605803 1.66 ENSDART00000121813
wdr41
WD repeat domain 41
chr11_+_31121340 1.50 ENSDART00000185172
stx10
syntaxin 10
chr7_+_69187585 1.48 ENSDART00000160499
ENSDART00000166258
marveld3
MARVEL domain containing 3
chr3_-_36440705 1.35 ENSDART00000162875
rogdi
rogdi homolog (Drosophila)
chr3_-_54607166 1.27 ENSDART00000021977
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr10_-_35257458 1.26 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr25_-_17918536 1.21 ENSDART00000148660
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr5_-_45958838 1.20 ENSDART00000135072
poc5
POC5 centriolar protein homolog (Chlamydomonas)
chr2_+_9821757 1.17 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr7_+_35191220 1.12 ENSDART00000110552
zdhhc1
zinc finger, DHHC-type containing 1
chr24_-_23716097 1.11 ENSDART00000084954
ENSDART00000129028
pign
phosphatidylinositol glycan anchor biosynthesis, class N
chr13_+_15816573 1.09 ENSDART00000137061
klc1a
kinesin light chain 1a
chr13_-_40282770 1.06 ENSDART00000140875
zgc:123010
zgc:123010
chr21_+_31253048 1.06 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr18_+_27511976 1.03 ENSDART00000132017
ENSDART00000140781
tp53i11b
tumor protein p53 inducible protein 11b
chr8_+_10862353 1.01 ENSDART00000140717
brpf3b
bromodomain and PHD finger containing, 3b
chr11_-_35171768 1.00 ENSDART00000192896
traip
TRAF-interacting protein
chr6_-_12912606 1.00 ENSDART00000164640
ical1
islet cell autoantigen 1-like
chr3_+_51684963 0.97 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
baiap2a
BAI1-associated protein 2a
chr11_-_35171162 0.96 ENSDART00000017393
traip
TRAF-interacting protein
chr16_+_26612401 0.96 ENSDART00000145571
epb41l4b
erythrocyte membrane protein band 4.1 like 4B
chr20_+_6535176 0.96 ENSDART00000054652
si:ch211-191a24.4
si:ch211-191a24.4
chr20_+_6535438 0.95 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr6_+_37655078 0.90 ENSDART00000122199
ENSDART00000065127
cyfip1
cytoplasmic FMR1 interacting protein 1
chr12_+_38563073 0.90 ENSDART00000009172
ttyh2
tweety family member 2
chr22_+_34784075 0.90 ENSDART00000167538
lcor
ligand dependent nuclear receptor corepressor
chr11_+_13424116 0.90 ENSDART00000125563
homer3b
homer scaffolding protein 3b
chr13_-_42724645 0.88 ENSDART00000046066
capn1a
calpain 1, (mu/I) large subunit a
chr5_-_24029228 0.87 ENSDART00000051546
rps6ka3a
ribosomal protein S6 kinase a, polypeptide 3a
chr9_-_19489264 0.86 ENSDART00000122894
wdr4
WD repeat domain 4
chr25_+_418932 0.81 ENSDART00000059193
prtgb
protogenin homolog b (Gallus gallus)
chr2_+_9822319 0.80 ENSDART00000144078
ENSDART00000144371
anxa13l
annexin A13, like
chr11_+_13423776 0.80 ENSDART00000102553
homer3b
homer scaffolding protein 3b
chr25_-_17918810 0.79 ENSDART00000023959
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr1_-_59240975 0.78 ENSDART00000166170
mvb12a
multivesicular body subunit 12A
chr24_+_35387517 0.77 ENSDART00000058571
snai2
snail family zinc finger 2
chr3_-_37148594 0.77 ENSDART00000140855
mlx
MLX, MAX dimerization protein
chr16_-_44945224 0.76 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr13_+_22712406 0.74 ENSDART00000132847
si:ch211-134m17.9
si:ch211-134m17.9
chr16_+_10329701 0.74 ENSDART00000172845
mdc1
mediator of DNA damage checkpoint 1
chr16_+_39159752 0.73 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr7_-_33684632 0.73 ENSDART00000130553
tle3b
transducin-like enhancer of split 3b
chr18_-_22735002 0.72 ENSDART00000023721
nudt21
nudix hydrolase 21
chr14_-_33277743 0.72 ENSDART00000048130
stard14
START domain containing 14
chr2_+_37836821 0.71 ENSDART00000143203
parp2
poly (ADP-ribose) polymerase 2
chr14_-_33278084 0.70 ENSDART00000132850
stard14
START domain containing 14
chr16_-_41667101 0.70 ENSDART00000084528
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr12_-_3778848 0.70 ENSDART00000152128
si:ch211-166g5.4
si:ch211-166g5.4
chr11_+_18612166 0.69 ENSDART00000162694
ncoa3
nuclear receptor coactivator 3
chr8_-_15182232 0.68 ENSDART00000138855
bcar3
BCAR3, NSP family adaptor protein
chr11_-_2297832 0.68 ENSDART00000158266
znf740a
zinc finger protein 740a
chr19_+_20201254 0.68 ENSDART00000010140
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr8_+_11425048 0.66 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr18_-_38270430 0.65 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr18_-_38270077 0.65 ENSDART00000185546
caprin1b
cell cycle associated protein 1b
chr18_-_35459996 0.65 ENSDART00000141023
itpkcb
inositol-trisphosphate 3-kinase Cb
chr5_+_60928576 0.65 ENSDART00000131041
doc2b
double C2-like domains, beta
chr7_+_13609457 0.64 ENSDART00000172857
ankdd1a
ankyrin repeat and death domain containing 1A
chr18_-_35459605 0.63 ENSDART00000135691
itpkcb
inositol-trisphosphate 3-kinase Cb
chr24_-_25096199 0.62 ENSDART00000185076
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr19_-_425145 0.61 ENSDART00000164905
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr4_-_20235904 0.60 ENSDART00000146621
ENSDART00000193655
stk38l
serine/threonine kinase 38 like
chr6_+_50393047 0.60 ENSDART00000055502
ENSDART00000055511
ergic3
ERGIC and golgi 3
chr5_+_44064764 0.60 ENSDART00000143843
si:dkey-84j12.1
si:dkey-84j12.1
chr16_-_6849754 0.60 ENSDART00000149206
ENSDART00000149778
mbpb
myelin basic protein b
chr24_+_21684189 0.60 ENSDART00000014696
pdx1
pancreatic and duodenal homeobox 1
chr1_+_35495368 0.60 ENSDART00000053806
gab1
GRB2-associated binding protein 1
chr19_+_20201593 0.60 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr3_-_42086577 0.58 ENSDART00000083111
ENSDART00000187312
ttyh3a
tweety family member 3a
chr2_-_15040345 0.58 ENSDART00000109657
si:dkey-10f21.4
si:dkey-10f21.4
chr20_-_45772306 0.57 ENSDART00000062092
trmt6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr16_-_31824525 0.57 ENSDART00000058737
cdc42l
cell division cycle 42, like
chr12_+_19199735 0.55 ENSDART00000066393
pdap1a
pdgfa associated protein 1a
chr7_+_39054478 0.54 ENSDART00000173825
dgkza
diacylglycerol kinase, zeta a
chr19_-_12193622 0.53 ENSDART00000041960
ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr22_+_22437561 0.53 ENSDART00000089622
kif14
kinesin family member 14
chr23_-_18415872 0.51 ENSDART00000135430
fam120c
family with sequence similarity 120C
chr13_+_15657911 0.51 ENSDART00000134972
ENSDART00000138991
ENSDART00000133342
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr13_+_13681681 0.49 ENSDART00000057825
cfd
complement factor D (adipsin)
chr11_-_6452444 0.49 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr4_+_6833735 0.48 ENSDART00000136355
dock4b
dedicator of cytokinesis 4b
chr9_+_54984900 0.48 ENSDART00000191622
mospd2
motile sperm domain containing 2
chr4_-_75057322 0.47 ENSDART00000157935
large1
LARGE xylosyl- and glucuronyltransferase 1
chr6_-_24103666 0.47 ENSDART00000164915
scinla
scinderin like a
chr9_+_54984537 0.47 ENSDART00000029528
mospd2
motile sperm domain containing 2
chr4_+_6833583 0.46 ENSDART00000165179
ENSDART00000186134
ENSDART00000174507
dock4b
dedicator of cytokinesis 4b
chr19_+_40322912 0.45 ENSDART00000146893
cdk6
cyclin-dependent kinase 6
chr20_+_4157815 0.44 ENSDART00000113132
gnpat
glyceronephosphate O-acyltransferase
chr9_+_44722205 0.43 ENSDART00000086176
ENSDART00000145271
ENSDART00000132696
nckap1
NCK-associated protein 1
chr7_+_22801465 0.42 ENSDART00000052862
ENSDART00000173633
rbm4.1
RNA binding motif protein 4.1
chr7_-_66133786 0.42 ENSDART00000154961
btbd10b
BTB (POZ) domain containing 10b
chr2_+_34967022 0.41 ENSDART00000134926
astn1
astrotactin 1
chr5_+_43965078 0.41 ENSDART00000113502
ENSDART00000187143
TMEM8B
si:dkey-84j12.1
chr6_-_3924543 0.41 ENSDART00000170584
tlk1b
tousled-like kinase 1b
chr23_-_29505463 0.41 ENSDART00000050915
kif1b
kinesin family member 1B
chr6_-_3924723 0.40 ENSDART00000171804
tlk1b
tousled-like kinase 1b
chr9_+_48007081 0.40 ENSDART00000060593
ENSDART00000099835
zgc:92380
zgc:92380
chr8_-_51954562 0.39 ENSDART00000132527
ENSDART00000057315
cep78
centrosomal protein 78
chr7_+_30201611 0.38 ENSDART00000075588
wdr76
WD repeat domain 76
chr14_+_49007501 0.38 ENSDART00000128508
zdhhc5b
zinc finger, DHHC-type containing 5b
chr17_+_9308425 0.38 ENSDART00000188283
ENSDART00000183311
NPAS3
neuronal PAS domain protein 3
chr7_+_30202104 0.37 ENSDART00000173525
wdr76
WD repeat domain 76
chr5_+_57773222 0.36 ENSDART00000135344
ppp2r1ba
protein phosphatase 2, regulatory subunit A, beta a
chr12_+_21299338 0.35 ENSDART00000074540
ENSDART00000133188
ca10a
carbonic anhydrase Xa
chr11_+_35171406 0.35 ENSDART00000110839
mon1a
MON1 secretory trafficking family member A
chr23_-_3721444 0.35 ENSDART00000141682
nudt3a
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr19_-_31707892 0.35 ENSDART00000088427
ripor2
RHO family interacting cell polarization regulator 2
chr2_+_31838442 0.34 ENSDART00000066789
stard3nl
STARD3 N-terminal like
chr7_+_7019911 0.34 ENSDART00000172421
rbm14b
RNA binding motif protein 14b
chr2_+_34967210 0.34 ENSDART00000141796
astn1
astrotactin 1
chr23_-_29505645 0.34 ENSDART00000146458
kif1b
kinesin family member 1B
chr19_-_9503473 0.32 ENSDART00000091615
iffo1a
intermediate filament family orphan 1a
chr4_+_13615731 0.32 ENSDART00000141395
ENSDART00000144310
ccdc87
coiled-coil domain containing 87
chr4_-_14624481 0.31 ENSDART00000137847
plxnb2a
plexin b2a
chr17_+_49127003 0.31 ENSDART00000157360
tiam2a
T cell lymphoma invasion and metastasis 2a
chr7_+_9981757 0.31 ENSDART00000113429
ENSDART00000173233
adamts17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr17_-_37195163 0.31 ENSDART00000108514
asxl2
additional sex combs like transcriptional regulator 2
chr17_+_24687338 0.30 ENSDART00000135794
selenon
selenoprotein N
chr20_-_43917647 0.29 ENSDART00000026213
mark3b
MAP/microtubule affinity-regulating kinase 3b
chr8_-_16515127 0.29 ENSDART00000146469
ENSDART00000132681
ttc39a
tetratricopeptide repeat domain 39A
chr11_-_6877973 0.29 ENSDART00000160271
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr14_-_47391084 0.28 ENSDART00000159608
fstl5
follistatin-like 5
chr13_-_24396199 0.26 ENSDART00000181093
tbp
TATA box binding protein
chr17_+_34805897 0.26 ENSDART00000137090
ENSDART00000077626
id2a
inhibitor of DNA binding 2a
chr11_-_24532988 0.25 ENSDART00000067078
plekhg5a
pleckstrin homology domain containing, family G (with RhoGef domain) member 5a
chr14_-_31151148 0.24 ENSDART00000026569
gpc4
glypican 4
chr9_+_19489304 0.24 ENSDART00000151920
si:ch211-140m22.7
si:ch211-140m22.7
chr3_-_30941362 0.22 ENSDART00000076830
coro1a
coronin, actin binding protein, 1A
chr6_+_45494227 0.22 ENSDART00000159863
cntn4
contactin 4
chr9_+_6255973 0.22 ENSDART00000078525
uxs1
UDP-glucuronate decarboxylase 1
chr7_-_72208248 0.21 ENSDART00000108916
zmp:0000001168
zmp:0000001168
chr12_+_4845448 0.21 ENSDART00000160666
ghrhr2
growth hormone releasing hormone receptor 2
chr9_+_6255682 0.21 ENSDART00000149827
uxs1
UDP-glucuronate decarboxylase 1
chr23_-_10137322 0.21 ENSDART00000142442
plxnb1a
plexin b1a
chr14_+_35023923 0.20 ENSDART00000172171
ebf3a
early B cell factor 3a
chr7_+_28960518 0.20 ENSDART00000182903
ENSDART00000188250
ENSDART00000191830
dok4
docking protein 4
chr12_-_26022663 0.19 ENSDART00000166769
bmpr1ab
bone morphogenetic protein receptor, type IAb
chr14_-_9713549 0.18 ENSDART00000193356
ENSDART00000166739
si:zfos-2326c3.2
si:zfos-2326c3.2
chr3_+_23691847 0.16 ENSDART00000078453
hoxb7a
homeobox B7a
chr3_+_36972586 0.16 ENSDART00000102784
si:ch211-18i17.2
si:ch211-18i17.2
chr20_-_29864390 0.16 ENSDART00000161834
ENSDART00000132278
rnf144ab
ring finger protein 144ab
chr14_-_45512807 0.14 ENSDART00000173172
si:ch211-114c17.1
si:ch211-114c17.1
chr4_-_27897160 0.13 ENSDART00000066924
ENSDART00000066925
ENSDART00000193020
tbc1d22a
TBC1 domain family, member 22a
chr8_-_1266181 0.13 ENSDART00000148654
ENSDART00000149924
cdc14b
cell division cycle 14B
chr19_+_4892281 0.12 ENSDART00000150969
cdk12
cyclin-dependent kinase 12
chr21_-_11327830 0.12 ENSDART00000122331
rtkn2b
rhotekin 2b
chr5_-_37871526 0.11 ENSDART00000136450
arhgap35b
Rho GTPase activating protein 35b
chr7_+_39360797 0.11 ENSDART00000173481
acp2
acid phosphatase 2, lysosomal
chr20_+_13783040 0.10 ENSDART00000115329
ENSDART00000152497
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr16_-_17560822 0.09 ENSDART00000089230
casp2
caspase 2, apoptosis-related cysteine peptidase
chr19_-_28130658 0.08 ENSDART00000079114
irx1b
iroquois homeobox 1b
chr5_+_36439405 0.08 ENSDART00000102973
eda
ectodysplasin A
chr3_+_19299309 0.07 ENSDART00000046297
ENSDART00000146955
ldlra
low density lipoprotein receptor a
chr3_+_36972298 0.07 ENSDART00000150917
si:ch211-18i17.2
si:ch211-18i17.2
chr21_+_26733529 0.07 ENSDART00000168379
pcxa
pyruvate carboxylase a
chr13_-_9119867 0.07 ENSDART00000137255
si:dkey-112g5.15
si:dkey-112g5.15
chr9_+_3055566 0.06 ENSDART00000189906
ENSDART00000175891
ENSDART00000093021
ppp1r9ala
protein phosphatase 1 regulatory subunit 9A-like A
chr9_-_1965727 0.05 ENSDART00000082354
hoxd9a
homeobox D9a
chr23_+_25232711 0.05 ENSDART00000128510
erbb3b
erb-b2 receptor tyrosine kinase 3b
chr12_+_8474868 0.05 ENSDART00000062858
adoa
2-aminoethanethiol (cysteamine) dioxygenase a
chr17_-_37395460 0.05 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr1_+_18863060 0.05 ENSDART00000139241
rnf38
ring finger protein 38
chr8_+_37111643 0.04 ENSDART00000061336
ren
renin
chr19_+_29798064 0.04 ENSDART00000167803
ENSDART00000051804
marcksl1b
MARCKS-like 1b
chr20_+_34596205 0.04 ENSDART00000138338
si:ch211-242b18.1
si:ch211-242b18.1
chr4_-_42242844 0.04 ENSDART00000163476
si:ch211-129p6.2
si:ch211-129p6.2
chr17_-_33552363 0.03 ENSDART00000154400
tmem121aa
transmembrane protein 121Aa
chr16_+_10422836 0.02 ENSDART00000161568
ino80e
INO80 complex subunit E
chr10_-_34867401 0.02 ENSDART00000145545
dclk1a
doublecortin-like kinase 1a
chr23_+_25232411 0.01 ENSDART00000138974
erbb3b
erb-b2 receptor tyrosine kinase 3b
chr19_-_31584444 0.01 ENSDART00000052183
zgc:111986
zgc:111986
chr5_-_23715861 0.01 ENSDART00000019992
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr14_-_6943934 0.01 ENSDART00000126279
clk4a
CDC-like kinase 4a
chr5_-_58832332 0.01 ENSDART00000161230
arhgef12b
Rho guanine nucleotide exchange factor (GEF) 12b
chr9_+_13638329 0.01 ENSDART00000143432
als2a
amyotrophic lateral sclerosis 2a (juvenile)
chr16_-_45235947 0.00 ENSDART00000164436
si:dkey-33i11.4
si:dkey-33i11.4
chr16_-_54978981 0.00 ENSDART00000154023
wdtc1
WD and tetratricopeptide repeats 1
chr1_+_1805294 0.00 ENSDART00000103850
atp1a1a.3
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3

Network of associatons between targets according to the STRING database.

First level regulatory network of gfi1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.3 0.9 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 1.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.3 0.8 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.3 1.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.2 0.7 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.2 1.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.7 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.2 0.9 GO:0099563 modification of synaptic structure(GO:0099563)
0.2 0.9 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.2 0.7 GO:0060074 synapse maturation(GO:0060074)
0.2 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.7 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 1.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.3 GO:2000402 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.4 GO:1901906 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.6 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 2.3 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.1 1.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.6 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.2 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 2.0 GO:0009648 photoperiodism(GO:0009648)
0.0 0.4 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.0 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.2 GO:0007632 visual behavior(GO:0007632)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269) skeletal muscle tissue regeneration(GO:0043403)
0.0 1.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.7 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0043588 skin development(GO:0043588)
0.0 0.1 GO:0048939 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.0 0.6 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.5 GO:0048278 vesicle docking(GO:0048278)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.0 1.3 GO:0051028 mRNA transport(GO:0051028)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 1.6 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 1.5 GO:0006821 chloride transport(GO:0006821)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0043291 RAVE complex(GO:0043291)
0.2 0.7 GO:0042382 paraspeckles(GO:0042382)
0.2 1.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 2.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.1 2.0 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.3 GO:0031209 SCAR complex(GO:0031209)
0.1 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.6 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 1.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 1.0 GO:0030175 filopodium(GO:0030175)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 1.5 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.3 1.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 1.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 1.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 2.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 0.8 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.7 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.6 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.0 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.7 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.4 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.9 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 2.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.3 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 2.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 1.3 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways