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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for gli1+gli2b

Z-value: 0.49

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Transcription factors associated with gli1+gli2b

Gene Symbol Gene ID Gene Info
gli2b
ENSDARG00000020884 GLI family zinc finger 2b
gli1
ENSDARG00000101244 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gli1dr11_v1_chr6_-_59505589_59505589-0.857.9e-06Click!
gli2bdr11_v1_chr11_+_43661735_436617350.542.1e-02Click!

Activity profile of gli1+gli2b motif

Sorted Z-values of gli1+gli2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_15155684 1.06 ENSDART00000167966
zgc:158852
zgc:158852
chr7_-_4110462 1.03 ENSDART00000173318
zgc:55733
zgc:55733
chr20_-_41992878 1.00 ENSDART00000100967
si:dkeyp-114g9.1
si:dkeyp-114g9.1
chr24_-_17029374 0.96 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr9_+_45227028 0.83 ENSDART00000185579
adarb1b
adenosine deaminase, RNA-specific, B1b
chr22_-_38459316 0.76 ENSDART00000149683
ENSDART00000098461
ptk7a
protein tyrosine kinase 7a
chr13_-_33317323 0.76 ENSDART00000110295
ENSDART00000144848
ENSDART00000136701
tmem234
transmembrane protein 234
chr10_+_16036573 0.75 ENSDART00000188757
lmnb1
lamin B1
chr15_+_25489406 0.75 ENSDART00000162482
zgc:152863
zgc:152863
chr18_-_158541 0.74 ENSDART00000188914
ENSDART00000191052
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr22_-_22340688 0.73 ENSDART00000105597
si:ch211-129c21.1
si:ch211-129c21.1
chr22_-_22147375 0.72 ENSDART00000149304
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr10_+_16036246 0.72 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr1_+_54737353 0.72 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr18_-_40753583 0.70 ENSDART00000026767
akt2
v-akt murine thymoma viral oncogene homolog 2
chr11_+_5468629 0.68 ENSDART00000013203
cse1l
CSE1 chromosome segregation 1-like (yeast)
chr19_-_8926575 0.67 ENSDART00000080897
rprd2a
regulation of nuclear pre-mRNA domain containing 2a
chr14_+_28486213 0.64 ENSDART00000161852
stag2b
stromal antigen 2b
chr17_-_4252221 0.62 ENSDART00000152020
gdf3
growth differentiation factor 3
chr1_-_14506759 0.61 ENSDART00000057044
si:dkey-194g4.1
si:dkey-194g4.1
chr2_-_57707039 0.61 ENSDART00000097685
CABZ01060891.1

chr19_+_7424347 0.60 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr24_+_39641991 0.56 ENSDART00000142182
luc7l
LUC7-like (S. cerevisiae)
chr5_+_13472234 0.56 ENSDART00000114069
ENSDART00000132406
cnnm4b
cyclin and CBS domain divalent metal cation transport mediator 4b
chr20_+_51730658 0.54 ENSDART00000010271
aida
axin interactor, dorsalization associated
chr14_-_15155384 0.54 ENSDART00000172666
uvssa
UV-stimulated scaffold protein A
chr15_+_24737599 0.52 ENSDART00000078024
crk
v-crk avian sarcoma virus CT10 oncogene homolog
chr2_+_51783120 0.51 ENSDART00000177559
crygn1
crystallin, gamma N1
chr1_+_19434198 0.51 ENSDART00000012552
clockb
clock circadian regulator b
chr7_+_10701938 0.49 ENSDART00000158162
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr19_-_46566430 0.49 ENSDART00000166668
ext1b
exostosin glycosyltransferase 1b
chr1_-_9527200 0.49 ENSDART00000110790
si:ch73-12o23.1
si:ch73-12o23.1
chr19_+_48060464 0.48 ENSDART00000123163
zgc:85936
zgc:85936
chr25_+_14697247 0.48 ENSDART00000180747
mpped2
metallophosphoesterase domain containing 2b
chr7_+_10701770 0.47 ENSDART00000167323
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr12_+_13091842 0.46 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
si:ch211-103b1.2
chr23_+_4226341 0.45 ENSDART00000012445
zgc:113278
zgc:113278
chr6_+_27090800 0.45 ENSDART00000121558
atg4b
autophagy related 4B, cysteine peptidase
chr24_+_39518774 0.45 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr21_-_17037907 0.44 ENSDART00000101263
ube2g1b
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr20_-_51186524 0.44 ENSDART00000027836
ENSDART00000114407
rbm25b
RNA binding motif protein 25b
chr5_+_66326004 0.43 ENSDART00000144351
malt1
MALT paracaspase 1
chr13_+_7242916 0.43 ENSDART00000184238
aifm2
apoptosis-inducing factor, mitochondrion-associated, 2
chr22_+_26665422 0.42 ENSDART00000164994
adcy9
adenylate cyclase 9
chr19_+_9050852 0.42 ENSDART00000151031
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr16_+_13822137 0.42 ENSDART00000163251
flcn
folliculin
chr13_-_865193 0.41 ENSDART00000187053
AL929536.7

chr9_+_4252839 0.40 ENSDART00000169740
kalrna
kalirin RhoGEF kinase a
chr3_+_34986837 0.39 ENSDART00000190341
smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr25_-_34740627 0.39 ENSDART00000137665
frs2b
fibroblast growth factor receptor substrate 2b
chr13_+_15657911 0.38 ENSDART00000134972
ENSDART00000138991
ENSDART00000133342
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr17_-_17447899 0.38 ENSDART00000156928
ENSDART00000109034
nrxn3a
neurexin 3a
chr13_-_1423008 0.38 ENSDART00000110828
znf451
zinc finger protein 451
chr14_+_49233896 0.36 ENSDART00000159526
rmnd5b
required for meiotic nuclear division 5 homolog B
chr11_+_24314148 0.34 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr13_-_50002852 0.34 ENSDART00000099439
lyst
lysosomal trafficking regulator
chr5_+_52844681 0.34 ENSDART00000162459
ENSDART00000184914
scarb2a
scavenger receptor class B, member 2a
chr3_-_33941319 0.34 ENSDART00000026090
ENSDART00000111878
gtf2f1
general transcription factor IIF, polypeptide 1
chr9_-_46072805 0.33 ENSDART00000169682
hdac4
histone deacetylase 4
chr3_+_45365098 0.33 ENSDART00000052746
ENSDART00000156555
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr24_+_39137001 0.32 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr17_+_34215886 0.32 ENSDART00000186775
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr5_-_17876709 0.31 ENSDART00000141978
si:dkey-112e17.1
si:dkey-112e17.1
chr14_-_16476863 0.30 ENSDART00000089021
canx
calnexin
chr2_+_54086436 0.29 ENSDART00000174581
CU179656.1

chr15_-_19128705 0.28 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr11_+_2855430 0.28 ENSDART00000172837
kif21b
kinesin family member 21B
chr5_-_57311037 0.27 ENSDART00000149855
fer
fer (fps/fes related) tyrosine kinase
chr15_-_43287515 0.26 ENSDART00000155103
prss16
protease, serine, 16 (thymus)
chr3_+_45368973 0.26 ENSDART00000187282
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr6_-_3982783 0.24 ENSDART00000171944
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr2_-_30784198 0.24 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr3_-_21062706 0.24 ENSDART00000155605
ENSDART00000153686
ENSDART00000157168
ENSDART00000156614
ENSDART00000155743
ENSDART00000156275
fam57ba
family with sequence similarity 57, member Ba
chr9_-_10145795 0.23 ENSDART00000004745
ENSDART00000143295
hnmt
histamine N-methyltransferase
chr2_+_42005217 0.23 ENSDART00000143562
gbp2
guanylate binding protein 2
chr4_+_10721795 0.23 ENSDART00000136000
ENSDART00000067253
stab2
stabilin 2
chr5_+_30596822 0.23 ENSDART00000188375
hinfp
histone H4 transcription factor
chr12_-_31422433 0.22 ENSDART00000186075
ENSDART00000153172
ENSDART00000066256
vti1a
vesicle transport through interaction with t-SNAREs 1A
chr22_-_18546241 0.22 ENSDART00000105404
ENSDART00000105405
cirbpb
cold inducible RNA binding protein b
chr21_-_44731865 0.20 ENSDART00000013814
ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr19_-_6988837 0.20 ENSDART00000145741
ENSDART00000167640
znf384l
zinc finger protein 384 like
chr20_+_13969414 0.19 ENSDART00000049864
rd3
retinal degeneration 3
chr13_+_6219551 0.19 ENSDART00000025910
apmap
adipocyte plasma membrane associated protein
chr1_+_59146298 0.18 ENSDART00000191885
ENSDART00000152747
gpr108
G protein-coupled receptor 108
chr7_+_53156810 0.18 ENSDART00000189816
cdh29
cadherin 29
chr2_+_46589798 0.18 ENSDART00000128457
ENSDART00000145347
ephb1
EPH receptor B1
chr10_-_44411032 0.18 ENSDART00000111509
CABZ01072096.1

chr3_+_19621034 0.16 ENSDART00000025358
itgb3a
integrin beta 3a
chr13_-_40754499 0.16 ENSDART00000111641
ENSDART00000159255
morn4
MORN repeat containing 4
chr14_+_15430991 0.15 ENSDART00000158221
si:dkey-203a12.5
si:dkey-203a12.5
chr6_-_30859656 0.15 ENSDART00000156235
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr21_+_261490 0.14 ENSDART00000177919
jak2a
Janus kinase 2a
chr16_-_30885838 0.14 ENSDART00000131356
dennd3b
DENN/MADD domain containing 3b
chr2_+_42005475 0.14 ENSDART00000056461
gbp2
guanylate binding protein 2
chr17_-_27200634 0.14 ENSDART00000185332
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr6_-_31326398 0.13 ENSDART00000190749
ENSDART00000192789
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr19_-_34995629 0.13 ENSDART00000141704
si:rp71-45k5.2
si:rp71-45k5.2
chr4_-_2219705 0.13 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr5_+_69878693 0.12 ENSDART00000073671
ythdc1
YTH domain containing 1
chr10_-_45379831 0.12 ENSDART00000186205
CABZ01117348.1

chr8_-_14121634 0.12 ENSDART00000184946
bgna
biglycan a
chr22_+_15979430 0.11 ENSDART00000189703
ENSDART00000192674
rc3h1a
ring finger and CCCH-type domains 1a
chr19_+_13994563 0.11 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr20_-_28642061 0.11 ENSDART00000135513
rgs6
regulator of G protein signaling 6
chr23_-_27152866 0.11 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr10_-_35542071 0.11 ENSDART00000162139
si:ch211-244c8.4
si:ch211-244c8.4
chr2_-_30784502 0.11 ENSDART00000056735
rgs20
regulator of G protein signaling 20
chr12_+_30367371 0.11 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr15_-_38129845 0.11 ENSDART00000057095
si:dkey-24p1.1
si:dkey-24p1.1
chr25_+_32474031 0.10 ENSDART00000152124
sqor
sulfide quinone oxidoreductase
chr13_+_31583034 0.10 ENSDART00000111763
six6a
SIX homeobox 6a
chr1_-_470812 0.10 ENSDART00000192527
zgc:92518
zgc:92518
chr16_-_43041324 0.09 ENSDART00000155445
ENSDART00000156836
ENSDART00000154945
si:dkey-7j14.6
si:dkey-7j14.6
chr12_+_30367079 0.09 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr21_+_13389499 0.09 ENSDART00000151268
zgc:113162
zgc:113162
chr3_+_34121156 0.08 ENSDART00000174929
aldh3b1
aldehyde dehydrogenase 3 family, member B1
chr18_+_30567945 0.08 ENSDART00000078894
irf8
interferon regulatory factor 8
chr6_+_11850359 0.08 ENSDART00000109552
ENSDART00000188139
ENSDART00000181499
ENSDART00000178269
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr6_+_28796773 0.08 ENSDART00000168237
ENSDART00000163541
tp63
tumor protein p63
chr16_-_22930925 0.08 ENSDART00000133819
si:dkey-246i14.3
si:dkey-246i14.3
chr23_+_4414343 0.07 ENSDART00000081821
wnt7ab
wingless-type MMTV integration site family, member 7Ab
chr19_+_49721 0.07 ENSDART00000160489
col14a1b
collagen, type XIV, alpha 1b
chr4_-_11077872 0.07 ENSDART00000150566
BX784029.4

chr5_+_40224938 0.07 ENSDART00000142897
si:dkey-193c22.2
si:dkey-193c22.2
chr5_-_25620594 0.07 ENSDART00000189346
cyp1d1
cytochrome P450, family 1, subfamily D, polypeptide 1
chr25_-_14637660 0.06 ENSDART00000143666
nav2b
neuron navigator 2b
chr9_-_46399611 0.05 ENSDART00000164914
ENSDART00000145931
lct
si:dkey-79p17.3
lactase
si:dkey-79p17.3
chr23_-_22130778 0.05 ENSDART00000079212
phc2a
polyhomeotic homolog 2a (Drosophila)
chr23_-_33038423 0.05 ENSDART00000180539
plxna2
plexin A2
chr15_+_7992906 0.05 ENSDART00000090790
cadm2b
cell adhesion molecule 2b
chr23_+_4414164 0.04 ENSDART00000192762
wnt7ab
wingless-type MMTV integration site family, member 7Ab
chr10_+_43188678 0.04 ENSDART00000012522
vcanb
versican b
chr4_+_27130412 0.04 ENSDART00000145083
brd1a
bromodomain containing 1a
chr10_+_5645887 0.04 ENSDART00000171426
pdzph1
PDZ and pleckstrin homology domains 1
chr9_+_56194410 0.04 ENSDART00000168530
LO018176.1

chr3_-_8285123 0.04 ENSDART00000158699
ENSDART00000138588
trim35-9
tripartite motif containing 35-9
chr18_-_16395668 0.04 ENSDART00000186004
mgat4c
mgat4 family, member C
chr20_+_35484070 0.03 ENSDART00000026234
ENSDART00000141675
mep1a.2
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr11_+_14295011 0.03 ENSDART00000060226
si:ch211-262i1.4
si:ch211-262i1.4
chr5_+_36439405 0.03 ENSDART00000102973
eda
ectodysplasin A
chr4_+_28997595 0.03 ENSDART00000133357
si:dkey-13e3.1
si:dkey-13e3.1
chr6_-_11768198 0.03 ENSDART00000183463
march7
membrane-associated ring finger (C3HC4) 7
chr1_+_57235896 0.03 ENSDART00000152621
si:dkey-27j5.7
si:dkey-27j5.7
chr23_+_34005792 0.03 ENSDART00000132668
si:ch211-207e14.4
si:ch211-207e14.4
chr4_+_77160027 0.03 ENSDART00000174060
ENSDART00000174364
znf1009
zinc finger protein 1009
chr2_-_38337122 0.03 ENSDART00000076523
ENSDART00000187473
slc7a8b
solute carrier family 7 (amino acid transporter light chain, L system), member 8b
chr8_+_1065458 0.03 ENSDART00000081432
sprb
sepiapterin reductase b
chr21_-_21465111 0.02 ENSDART00000141487
nectin3b
nectin cell adhesion molecule 3b
chr4_-_77506362 0.02 ENSDART00000174387
ENSDART00000181181
CABZ01087415.1

chr21_+_11560153 0.02 ENSDART00000065842
cd8a
CD8a molecule
chr24_-_21587335 0.02 ENSDART00000091528
gpr12
G protein-coupled receptor 12
chr15_-_35212462 0.02 ENSDART00000043960
agfg1a
ArfGAP with FG repeats 1a
chr4_-_72101234 0.02 ENSDART00000167048
slco1f1
solute carrier organic anion transporter family, member 1F1
chr10_-_40490647 0.02 ENSDART00000143660
taar20x
trace amine associated receptor 20x
chr4_+_63253425 0.01 ENSDART00000193510
si:ch211-258f1.3
si:ch211-258f1.3
chr4_-_17741513 0.01 ENSDART00000141680
mybpc1
myosin binding protein C, slow type
chr4_-_5856200 0.01 ENSDART00000121936
slc5a8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr1_+_59090583 0.01 ENSDART00000150658
mfap4
microfibril associated protein 4
chr4_+_58016732 0.01 ENSDART00000165777
CT027609.1

chr13_-_38039871 0.01 ENSDART00000140645
CR456624.1

chr22_-_24858042 0.01 ENSDART00000137998
ENSDART00000078216
ENSDART00000138378
vtg7
vitellogenin 7
chrM_+_9735 0.01 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr22_+_31207799 0.01 ENSDART00000133267
grip2b
glutamate receptor interacting protein 2b
chr22_+_38762693 0.00 ENSDART00000015016
ENSDART00000150187
alpi.1
alkaline phosphatase, intestinal, tandem duplicate 1
chr25_+_32473433 0.00 ENSDART00000152326
sqor
sulfide quinone oxidoreductase
chr20_+_27194833 0.00 ENSDART00000150072
si:dkey-85n7.8
si:dkey-85n7.8
chr22_-_3261879 0.00 ENSDART00000159643
gpr35.1
G protein-coupled receptor 35, tandem duplicate 1

Network of associatons between targets according to the STRING database.

First level regulatory network of gli1+gli2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.2 0.7 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.7 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.6 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.6 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.7 GO:0007589 body fluid secretion(GO:0007589)
0.1 0.8 GO:2000095 cerebrospinal fluid circulation(GO:0090660) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 1.0 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.6 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.8 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.3 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.4 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.4 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter(GO:0060260) regulation of DNA-templated transcription, initiation(GO:2000142)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.5 GO:0009648 photoperiodism(GO:0009648)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.4 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.3 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.7 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 0.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.2 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0048730 epidermis morphogenesis(GO:0048730)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:0034657 GID complex(GO:0034657)
0.1 1.0 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0016586 RSC complex(GO:0016586)
0.0 0.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0008278 cohesin complex(GO:0008278)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.4 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.1 0.8 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.7 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis