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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for gsc

Z-value: 0.61

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Transcription factors associated with gsc

Gene Symbol Gene ID Gene Info
gsc
ENSDARG00000059073 goosecoid
gsc
ENSDARG00000111184 goosecoid
gsc
ENSDARG00000115937 goosecoid

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
gscdr11_v1_chr17_-_19345521_19345521-0.691.6e-03Click!

Activity profile of gsc motif

Sorted Z-values of gsc motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_2841205 2.09 ENSDART00000131505
ENSDART00000055869
ykt6
YKT6 v-SNARE homolog (S. cerevisiae)
chr22_-_22147375 1.39 ENSDART00000149304
cdc34a
cell division cycle 34 homolog (S. cerevisiae) a
chr1_-_44928987 1.34 ENSDART00000134635
si:dkey-9i23.15
si:dkey-9i23.15
chr17_+_16090436 1.33 ENSDART00000136059
ENSDART00000138734
znf395a
zinc finger protein 395a
chr21_-_9562272 1.29 ENSDART00000162225
ENSDART00000163874
ENSDART00000168173
ptpn13
protein tyrosine phosphatase, non-receptor type 13
chr18_+_49969568 1.22 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr9_+_8396755 1.21 ENSDART00000043067
zgc:171776
zgc:171776
chr8_+_2656231 1.19 ENSDART00000160833
fam102aa
family with sequence similarity 102, member Aa
chr8_+_2656681 1.18 ENSDART00000185067
ENSDART00000165943
fam102aa
family with sequence similarity 102, member Aa
chr2_-_58075414 1.18 ENSDART00000161920
nectin4
nectin cell adhesion molecule 4
chr19_+_24068223 1.16 ENSDART00000141351
ENSDART00000100420
pex11b
peroxisomal biogenesis factor 11 beta
chr22_-_20695237 1.10 ENSDART00000112722
org
oogenesis-related gene
chr21_+_15756549 1.07 ENSDART00000026903
ptpra
protein tyrosine phosphatase, receptor type, A
chr17_+_35097024 1.01 ENSDART00000026152
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr7_+_66884291 1.00 ENSDART00000187499
sbf2
SET binding factor 2
chr14_-_45551572 0.99 ENSDART00000111410
ganab
glucosidase, alpha; neutral AB
chr21_-_20945658 0.99 ENSDART00000079701
rnf180
ring finger protein 180
chr13_-_36525982 0.97 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr2_-_57264262 0.96 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
mbd3a
methyl-CpG binding domain protein 3a
chr5_+_25733774 0.93 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr19_-_11846958 0.89 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr2_-_32262287 0.86 ENSDART00000056621
ENSDART00000039717
fam49ba
family with sequence similarity 49, member Ba
chr18_+_6638726 0.84 ENSDART00000142755
ENSDART00000167781
c2cd5
C2 calcium-dependent domain containing 5
chr23_-_17509656 0.83 ENSDART00000148423
dnajc5ab
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr17_-_12249990 0.82 ENSDART00000177889
ENSDART00000155545
ahctf1
AT hook containing transcription factor 1
chr6_-_17999776 0.81 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
rptor
regulatory associated protein of MTOR, complex 1
chr14_-_25928899 0.81 ENSDART00000143518
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr8_-_25814263 0.81 ENSDART00000143397
taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_+_66884570 0.81 ENSDART00000082664
sbf2
SET binding factor 2
chr18_+_6638974 0.80 ENSDART00000162398
c2cd5
C2 calcium-dependent domain containing 5
chr24_-_24060460 0.76 ENSDART00000142813
abcc13
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr20_-_25643667 0.76 ENSDART00000137457
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr22_+_438714 0.71 ENSDART00000136491
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr19_-_6193067 0.71 ENSDART00000092656
ENSDART00000140347
erf
Ets2 repressor factor
chr5_+_60518611 0.70 ENSDART00000130565
ENSDART00000186310
tmem132e
transmembrane protein 132E
chrM_+_12897 0.70 ENSDART00000093622
mt-nd5
NADH dehydrogenase 5, mitochondrial
chr1_+_16574312 0.70 ENSDART00000187067
mtus1b
microtubule associated tumor suppressor 1b
chr3_+_46764278 0.69 ENSDART00000136051
ENSDART00000164930
prkcsh
protein kinase C substrate 80K-H
chr24_-_24060632 0.69 ENSDART00000090514
abcc13
ATP-binding cassette, sub-family C (CFTR/MRP), member 13
chr14_+_7699443 0.68 ENSDART00000123139
brd8
bromodomain containing 8
chr14_-_25935167 0.68 ENSDART00000139855
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr22_+_34701848 0.67 ENSDART00000082066
atpv0e2
ATPase H+ transporting V0 subunit e2
chr16_-_20932896 0.65 ENSDART00000180646
tax1bp1b
Tax1 (human T-cell leukemia virus type I) binding protein 1b
chr5_+_59030096 0.65 ENSDART00000179814
ENSDART00000110182
rabep1
rabaptin, RAB GTPase binding effector protein 1
chr3_-_49504023 0.64 ENSDART00000168108
prkacaa
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr20_-_34663209 0.64 ENSDART00000132545
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr7_-_9674073 0.64 ENSDART00000187902
lrrk1
leucine-rich repeat kinase 1
chr3_-_23513155 0.63 ENSDART00000170200
BX682558.1

chr2_-_32513538 0.63 ENSDART00000056640
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr5_-_24029228 0.62 ENSDART00000051546
rps6ka3a
ribosomal protein S6 kinase a, polypeptide 3a
chr15_+_45591669 0.61 ENSDART00000157459
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr17_-_8656155 0.59 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr8_+_21280360 0.58 ENSDART00000144488
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr11_+_31680513 0.58 ENSDART00000139900
ENSDART00000040305
diaph3
diaphanous-related formin 3
chr17_-_33414781 0.58 ENSDART00000142203
ENSDART00000034638
ccdc28a
coiled-coil domain containing 28A
chr16_-_22585289 0.57 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr15_-_26887028 0.56 ENSDART00000156292
si:dkey-243i1.1
si:dkey-243i1.1
chr20_-_24182689 0.55 ENSDART00000171184
map3k7
mitogen-activated protein kinase kinase kinase 7
chr20_+_34671386 0.54 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr12_+_5048044 0.53 ENSDART00000161548
ENSDART00000172607
kif22
kinesin family member 22
chr3_+_46764022 0.51 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr2_-_32387441 0.51 ENSDART00000148202
ubtfl
upstream binding transcription factor, like
chr1_+_27690 0.51 ENSDART00000162928
eed
embryonic ectoderm development
chr23_-_31060350 0.50 ENSDART00000145598
ENSDART00000191491
si:ch211-197l9.5
si:ch211-197l9.5
chr6_+_12527725 0.50 ENSDART00000149328
stk24b
serine/threonine kinase 24b (STE20 homolog, yeast)
chr18_+_21951551 0.50 ENSDART00000146261
ranbp10
RAN binding protein 10
chr2_-_30784198 0.50 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr24_-_24271629 0.50 ENSDART00000135060
rps6ka3b
ribosomal protein S6 kinase, polypeptide 3b
chr20_+_32473584 0.49 ENSDART00000192449
ostm1
osteopetrosis associated transmembrane protein 1
chr24_+_3478871 0.47 ENSDART00000111491
ENSDART00000134598
ENSDART00000142407
wdr37
WD repeat domain 37
chr24_+_37533728 0.46 ENSDART00000061203
rhot2
ras homolog family member T2
chr5_+_31791001 0.46 ENSDART00000043010
slc25a25b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr9_-_52598343 0.45 ENSDART00000167922
xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5
chr7_-_49594995 0.45 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr12_+_33460794 0.44 ENSDART00000007053
ENSDART00000142716
narf
nuclear prelamin A recognition factor
chr2_-_9696283 0.41 ENSDART00000165712
selenot1a
selenoprotein T, 1a
chr3_-_29891456 0.40 ENSDART00000151677
ENSDART00000014021
slc25a39
solute carrier family 25, member 39
chr19_+_3140313 0.39 ENSDART00000125504
zgc:86598
zgc:86598
chr16_+_11297703 0.39 ENSDART00000125158
znf574
zinc finger protein 574
chr5_+_47882319 0.39 ENSDART00000149316
rasa1a
RAS p21 protein activator (GTPase activating protein) 1a
chr12_-_19119176 0.37 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr2_+_30531726 0.36 ENSDART00000146518
ankrd33bb
ankyrin repeat domain 33Bb
chr25_-_32381642 0.36 ENSDART00000133872
ENSDART00000006124
cops2
COP9 signalosome subunit 2
chr6_-_19270484 0.36 ENSDART00000186894
ENSDART00000188709
zgc:174863
zgc:174863
chr19_+_18797623 0.36 ENSDART00000166172
ddah2
dimethylarginine dimethylaminohydrolase 2
chr14_+_30753666 0.36 ENSDART00000009385
ENSDART00000137782
ENSDART00000172778
yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr7_+_17063761 0.35 ENSDART00000182880
htatip2
HIV-1 Tat interactive protein 2
chr25_-_22889519 0.35 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr1_+_16573982 0.35 ENSDART00000166317
mtus1b
microtubule associated tumor suppressor 1b
chr3_+_14157090 0.35 ENSDART00000156766
si:ch211-108d22.2
si:ch211-108d22.2
chr20_+_37866686 0.34 ENSDART00000036546
vash2
vasohibin 2
chr24_-_7777389 0.33 ENSDART00000138541
rpgrip1
RPGR interacting protein 1
chr23_+_17509794 0.32 ENSDART00000148457
gid8b
GID complex subunit 8 homolog b (S. cerevisiae)
chr6_-_43283122 0.32 ENSDART00000186022
frmd4ba
FERM domain containing 4Ba
chr19_-_32944050 0.32 ENSDART00000137611
azin1b
antizyme inhibitor 1b
chr3_-_29891218 0.31 ENSDART00000142118
slc25a39
solute carrier family 25, member 39
chr21_-_28235361 0.31 ENSDART00000164458
nrxn2a
neurexin 2a
chr14_+_32838110 0.31 ENSDART00000158077
arr3b
arrestin 3b, retinal (X-arrestin)
chr7_-_57933736 0.30 ENSDART00000142580
ank2b
ankyrin 2b, neuronal
chr23_-_27152866 0.30 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr20_+_26987416 0.30 ENSDART00000012816
sel1l
sel-1 suppressor of lin-12-like (C. elegans)
chr10_+_6013076 0.30 ENSDART00000167613
ENSDART00000159216
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr1_+_41690402 0.29 ENSDART00000177298
fbxo41
F-box protein 41
chr18_-_38245062 0.29 ENSDART00000189092
nat10
N-acetyltransferase 10
chr13_+_39182099 0.28 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr20_-_20270191 0.28 ENSDART00000009356
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr20_+_37866861 0.27 ENSDART00000153220
vash2
vasohibin 2
chr8_-_48847772 0.27 ENSDART00000122458
wrap73
WD repeat containing, antisense to TP73
chr17_-_2685026 0.27 ENSDART00000191014
ENSDART00000179309
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr6_-_59381391 0.27 ENSDART00000157066
ppp1r16b
protein phosphatase 1, regulatory subunit 16B
chr23_-_25779995 0.26 ENSDART00000110670
si:dkey-21c19.3
si:dkey-21c19.3
chr24_-_16905018 0.26 ENSDART00000066759
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr11_-_15090118 0.25 ENSDART00000171118
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr10_-_41400049 0.25 ENSDART00000009838
gpat4
glycerol-3-phosphate acyltransferase 4
chr5_-_57526807 0.25 ENSDART00000022866
pisd
phosphatidylserine decarboxylase
chr23_+_39854566 0.25 ENSDART00000190423
ENSDART00000164473
ENSDART00000161881
si:ch73-217b7.1
si:ch73-217b7.1
chr23_+_6232895 0.25 ENSDART00000139795
syt2a
synaptotagmin IIa
chr18_-_21640389 0.23 ENSDART00000100857
slc38a8a
solute carrier family 38, member 8a
chr24_+_9881219 0.23 ENSDART00000036204
cdv3
carnitine deficiency-associated gene expressed in ventricle 3
chr19_+_18799319 0.22 ENSDART00000171843
ddah2
dimethylarginine dimethylaminohydrolase 2
chr14_+_32837914 0.22 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr6_-_33924883 0.22 ENSDART00000132762
ENSDART00000148142
ENSDART00000142213
akr1a1b
aldo-keto reductase family 1, member A1b (aldehyde reductase)
chr24_+_37825634 0.21 ENSDART00000129889
ift140
intraflagellar transport 140 homolog (Chlamydomonas)
chr7_-_21905851 0.20 ENSDART00000111066
ENSDART00000020288
epoa
erythropoietin a
chr15_+_42995381 0.20 ENSDART00000152222
acsl3a
acyl-CoA synthetase long chain family member 3a
chr14_+_32839535 0.20 ENSDART00000168975
arr3b
arrestin 3b, retinal (X-arrestin)
chr25_+_7299488 0.19 ENSDART00000184836
hmg20a
high mobility group 20A
chr21_+_33187992 0.19 ENSDART00000162745
ENSDART00000188388
BX072577.1

chr23_-_10137322 0.19 ENSDART00000142442
plxnb1a
plexin b1a
chr5_+_26199537 0.18 ENSDART00000144303
zgc:86811
zgc:86811
chr17_-_14559576 0.18 ENSDART00000162452
daam1a
dishevelled associated activator of morphogenesis 1a
chr3_-_10970502 0.18 ENSDART00000127500
CR382337.1

chr17_-_50010121 0.16 ENSDART00000122747
tmem30aa
transmembrane protein 30Aa
chr24_-_16904803 0.15 ENSDART00000165972
ENSDART00000149974
ENSDART00000149706
mtrr
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr14_+_21754521 0.14 ENSDART00000111839
kdm2ab
lysine (K)-specific demethylase 2Ab
chr18_-_25646286 0.14 ENSDART00000099511
ENSDART00000186890
si:ch211-13k12.2
si:ch211-13k12.2
chr19_+_2631565 0.14 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr10_+_36345176 0.14 ENSDART00000099397
or105-1
odorant receptor, family C, subfamily 105, member 1
chr7_+_52887701 0.14 ENSDART00000109973
tp53bp1
tumor protein p53 binding protein, 1
chr1_-_45177373 0.14 ENSDART00000143142
ENSDART00000034549
zgc:111983
zgc:111983
chr11_-_15090564 0.13 ENSDART00000162079
slc1a8a
solute carrier family 1 (glutamate transporter), member 8a
chr2_+_4146299 0.13 ENSDART00000173418
mib1
mindbomb E3 ubiquitin protein ligase 1
chr21_-_2348838 0.12 ENSDART00000160337
si:ch73-299h12.8
si:ch73-299h12.8
chr20_+_29587995 0.12 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr23_-_1587955 0.11 ENSDART00000136037
fndc7b
fibronectin type III domain containing 7b
chr20_-_18736281 0.11 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr22_+_661505 0.10 ENSDART00000149460
elf3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr10_-_25628555 0.10 ENSDART00000143978
tiam1a
T cell lymphoma invasion and metastasis 1a
chr14_+_44545092 0.10 ENSDART00000175454
lingo2a
leucine rich repeat and Ig domain containing 2a
chr4_+_33012407 0.08 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr2_+_4146606 0.07 ENSDART00000171170
mib1
mindbomb E3 ubiquitin protein ligase 1
chr23_+_13814978 0.07 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr3_-_5277041 0.07 ENSDART00000046995
txn2
thioredoxin 2
chr3_-_36209936 0.06 ENSDART00000175208
csnk1da
casein kinase 1, delta a
chr25_+_16079913 0.06 ENSDART00000146350
far1
fatty acyl CoA reductase 1
chr8_-_54077740 0.05 ENSDART00000027000
rho
rhodopsin
chr2_-_16986894 0.05 ENSDART00000145720
clcn2a
chloride channel, voltage-sensitive 2a
chr15_+_9053059 0.05 ENSDART00000012039
ppm1na
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr5_-_14390445 0.05 ENSDART00000026120
ap3m2
adaptor-related protein complex 3, mu 2 subunit
chr11_-_29563437 0.04 ENSDART00000163958
arhgef10la
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr2_+_36828746 0.04 ENSDART00000186638
nrd1a
nardilysin a (N-arginine dibasic convertase)
chr17_-_2690083 0.04 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr17_-_51202339 0.04 ENSDART00000167117
si:ch1073-469d17.2
si:ch1073-469d17.2
chr19_+_4061699 0.04 ENSDART00000158309
ENSDART00000166512
btr25
btr26
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr7_+_30970045 0.04 ENSDART00000155974
tjp1a
tight junction protein 1a
chr7_-_66864756 0.04 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr22_+_38581012 0.03 ENSDART00000169239
BX088728.1

chr1_-_11627289 0.03 ENSDART00000163312
si:dkey-26i13.3
si:dkey-26i13.3
chr17_-_15657029 0.03 ENSDART00000153925
fut9a
fucosyltransferase 9a
chr23_-_18981595 0.03 ENSDART00000147617
bcl2l1
bcl2-like 1
chr9_+_20519846 0.03 ENSDART00000109680
ENSDART00000142220
vtcn1
V-set domain containing T cell activation inhibitor 1
chr18_+_7639401 0.03 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr15_+_45640906 0.03 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr1_-_45146834 0.03 ENSDART00000144997
si:ch211-239f4.6
si:ch211-239f4.6
chr22_+_5103349 0.02 ENSDART00000083474
atcaya
ataxia, cerebellar, Cayman type a
chr3_-_33574576 0.02 ENSDART00000184881
CR847537.1

chr9_-_29544720 0.02 ENSDART00000130317
arhgap20
Rho GTPase activating protein 20
chr19_+_42693855 0.02 ENSDART00000136873
clasp2
cytoplasmic linker associated protein 2
chr16_+_29555801 0.02 ENSDART00000169425
ensab
endosulfine alpha b
chr11_+_36180349 0.02 ENSDART00000012940
grm2b
glutamate receptor, metabotropic 2b
chr25_+_16080181 0.01 ENSDART00000061753
far1
fatty acyl CoA reductase 1
chr7_-_17780048 0.01 ENSDART00000183336
si:dkey-106g10.7
si:dkey-106g10.7
chr24_+_5826005 0.01 ENSDART00000154930
si:ch211-157j23.5
si:ch211-157j23.5
chr14_+_33486179 0.01 ENSDART00000149254
cul4b
cullin 4B
chr2_+_29795833 0.01 ENSDART00000056750
si:ch211-207d6.2
si:ch211-207d6.2
chr9_+_21990095 0.01 ENSDART00000146829
ENSDART00000133515
ENSDART00000193582
si:dkey-57a22.13
si:dkey-57a22.13
chr7_-_18656069 0.01 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr2_+_36828243 0.01 ENSDART00000135754
ENSDART00000140474
nrd1a
nardilysin a (N-arginine dibasic convertase)
chr17_-_32426392 0.01 ENSDART00000148455
ENSDART00000149885
ENSDART00000179314
grhl1
grainyhead-like transcription factor 1
chr1_-_11596829 0.00 ENSDART00000140725
si:dkey-26i13.7
si:dkey-26i13.7
chr16_+_19536614 0.00 ENSDART00000112894
ENSDART00000079201
ENSDART00000139357
sp8b
sp8 transcription factor b
chr10_+_13279079 0.00 ENSDART00000135082
tmem267
transmembrane protein 267
chr1_-_11616142 0.00 ENSDART00000131668
si:dkey-26i13.5
si:dkey-26i13.5
chr15_-_38154616 0.00 ENSDART00000099392
irgq2
immunity-related GTPase family, q2

Network of associatons between targets according to the STRING database.

First level regulatory network of gsc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.3 1.6 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.3 0.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 1.0 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.2 1.2 GO:0016559 peroxisome fission(GO:0016559)
0.2 0.5 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.2 0.7 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.2 0.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.6 GO:0045428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.1 0.6 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.1 0.3 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.6 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.9 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.6 GO:0071331 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.1 0.2 GO:0021519 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 0.7 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.7 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.7 GO:0021754 facial nucleus development(GO:0021754)
0.1 1.2 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.8 GO:0071230 TORC1 signaling(GO:0038202) cellular response to amino acid stimulus(GO:0071230)
0.0 0.5 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.6 GO:0007099 centriole replication(GO:0007099)
0.0 0.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.5 GO:0034112 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:0043588 skin development(GO:0043588)
0.0 0.0 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.3 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.3 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.4 GO:0006099 tricarboxylic acid cycle(GO:0006099)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0017177 glucosidase II complex(GO:0017177)
0.1 1.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.8 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 1.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0003994 aconitate hydratase activity(GO:0003994)
0.1 0.4 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0030586 [methionine synthase] reductase activity(GO:0030586)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.9 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 1.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.7 GO:0016530 metallochaperone activity(GO:0016530)
0.1 0.7 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.3 GO:0017020 myosin phosphatase regulator activity(GO:0017020)
0.1 0.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.7 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.1 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 0.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase