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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for gsx2+pnx

Z-value: 1.35

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Transcription factors associated with gsx2+pnx

Gene Symbol Gene ID Gene Info
pnx
ENSDARG00000025899 posterior neuron-specific homeobox
gsx2
ENSDARG00000043322 GS homeobox 2
gsx2
ENSDARG00000116417 GS homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pnxdr11_v1_chr10_+_2799285_27992850.978.6e-11Click!
gsx2dr11_v1_chr20_-_22484621_224846210.644.3e-03Click!

Activity profile of gsx2+pnx motif

Sorted Z-values of gsx2+pnx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_33865312 6.56 ENSDART00000166141
tekt1
tektin 1
chr7_-_1504382 5.25 ENSDART00000172770
si:zfos-405g10.4
si:zfos-405g10.4
chr10_-_17083180 4.61 ENSDART00000170083
fam166b
family with sequence similarity 166, member B
chr11_-_40728380 4.57 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr6_-_40352215 4.39 ENSDART00000103992
ttll3
tubulin tyrosine ligase-like family, member 3
chr2_-_2957970 4.35 ENSDART00000162505
si:ch1073-82l19.1
si:ch1073-82l19.1
chr4_+_306036 4.17 ENSDART00000103659
msgn1
mesogenin 1
chr6_+_40354424 4.00 ENSDART00000047416
slc4a8
solute carrier family 4, sodium bicarbonate cotransporter, member 8
chr5_+_42308955 3.58 ENSDART00000136683
pimr201
Pim proto-oncogene, serine/threonine kinase, related 201
chr18_+_1154189 3.35 ENSDART00000135090
si:ch1073-75f15.2
si:ch1073-75f15.2
chr20_-_14925281 3.31 ENSDART00000152641
dnm3a
dynamin 3a
chr11_-_472547 3.19 ENSDART00000005923
zgc:77375
zgc:77375
chr1_-_17715493 3.18 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr20_-_1378514 3.03 ENSDART00000181830
scara5
scavenger receptor class A, member 5 (putative)
chr19_+_43978814 2.94 ENSDART00000102314
nkd3
naked cuticle homolog 3
chr21_+_43404945 2.90 ENSDART00000142234
frmd7
FERM domain containing 7
chr20_-_14924858 2.89 ENSDART00000047039
dnm3a
dynamin 3a
chr5_-_13564961 2.85 ENSDART00000146827
si:ch211-230g14.3
si:ch211-230g14.3
chr1_-_59287410 2.84 ENSDART00000158011
ENSDART00000170580
col5a3b
collagen, type V, alpha 3b
chr21_-_29991098 2.75 ENSDART00000155772
si:ch73-190f9.4
si:ch73-190f9.4
chr8_-_21372446 2.71 ENSDART00000061481
ENSDART00000079293
ela2l
elastase 2 like
chr8_-_24502997 2.68 ENSDART00000184801
ENSDART00000179794
BX296549.1

chr2_-_1569250 2.65 ENSDART00000167202
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr6_+_3280939 2.62 ENSDART00000151359
kdm4aa
lysine (K)-specific demethylase 4A, genome duplicate a
chr6_-_7720332 2.56 ENSDART00000135945
rpsa
ribosomal protein SA
chr16_-_13818061 2.54 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr1_+_50921266 2.30 ENSDART00000006538
otx2a
orthodenticle homeobox 2a
chr23_+_19813677 2.29 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr23_+_45966436 2.28 ENSDART00000172160
CABZ01069338.1

chr5_-_65969959 2.18 ENSDART00000170677
ttc16
tetratricopeptide repeat domain 16
chr18_+_3332999 2.16 ENSDART00000160857
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr25_+_31868268 2.11 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr7_-_24046999 2.11 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr18_-_36909773 2.11 ENSDART00000141694
si:ch211-160d20.5
si:ch211-160d20.5
chr13_-_6218248 2.02 ENSDART00000159052
si:zfos-1056e6.1
si:zfos-1056e6.1
chr3_-_39180048 1.98 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr3_-_23643751 1.93 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr10_+_35257651 1.93 ENSDART00000028940
styxl1
serine/threonine/tyrosine interacting-like 1
chr13_+_8677166 1.92 ENSDART00000181016
ENSDART00000135028
prop1
PROP paired-like homeobox 1
chr5_+_69747417 1.87 ENSDART00000153717
si:ch211-275j6.5
si:ch211-275j6.5
chr5_-_19394440 1.85 ENSDART00000163771
foxn4
forkhead box N4
chr20_+_535458 1.85 ENSDART00000152453
dse
dermatan sulfate epimerase
chr21_-_5205617 1.85 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr2_-_43124747 1.82 ENSDART00000188883
lrrc6
leucine rich repeat containing 6
chr15_-_36533322 1.76 ENSDART00000156466
ENSDART00000121755
si:dkey-262k9.4
si:dkey-262k9.4
chr17_+_3379673 1.76 ENSDART00000176354
sntg2
syntrophin, gamma 2
chr24_-_8777781 1.75 ENSDART00000082362
ENSDART00000177400
mak
male germ cell-associated kinase
chr25_+_5035343 1.70 ENSDART00000011751
parvb
parvin, beta
chr15_-_4528326 1.68 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr1_-_58963395 1.66 ENSDART00000130415
CABZ01115881.1

chr15_-_4969525 1.60 ENSDART00000157223
lipt2
lipoyl(octanoyl) transferase 2
chr3_+_62356578 1.59 ENSDART00000157030
iqck
IQ motif containing K
chr21_-_22827548 1.56 ENSDART00000079161
angptl5
angiopoietin-like 5
chr3_+_30500968 1.54 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr5_+_19343880 1.51 ENSDART00000148130
acacb
acetyl-CoA carboxylase beta
chr17_+_43908428 1.51 ENSDART00000180332
msh4
mutS homolog 4
chr20_-_46362606 1.49 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr7_-_48667056 1.47 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr13_+_30903816 1.47 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr14_-_36320506 1.47 ENSDART00000074639
egf
epidermal growth factor
chr4_+_72723304 1.45 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr15_+_15856178 1.41 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr11_+_26476153 1.39 ENSDART00000103507
unm_sa1614
un-named sa1614
chr19_+_3826782 1.39 ENSDART00000169222
oscp1a
organic solute carrier partner 1a
chr21_+_6751405 1.39 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr3_-_23407720 1.37 ENSDART00000155658
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr18_-_48547564 1.37 ENSDART00000138607
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr21_-_45077429 1.34 ENSDART00000187268
ENSDART00000191003
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr24_-_3783497 1.34 ENSDART00000158354
adarb2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr9_-_950004 1.33 ENSDART00000168917
SCTR
secretin receptor
chr2_-_43123949 1.32 ENSDART00000075347
ENSDART00000132346
lrrc6
leucine rich repeat containing 6
chr10_-_5847655 1.31 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr12_+_20352400 1.30 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr3_+_18398876 1.28 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr13_-_42400647 1.28 ENSDART00000043069
march5
membrane-associated ring finger (C3HC4) 5
chr10_-_26744131 1.26 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr21_+_25198637 1.25 ENSDART00000164972
si:dkey-183i3.6
si:dkey-183i3.6
chr21_-_45076778 1.24 ENSDART00000181525
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6
chr1_+_7517454 1.24 ENSDART00000016139
lancl1
LanC antibiotic synthetase component C-like 1 (bacterial)
chr10_+_26645953 1.23 ENSDART00000131482
adgrg4b
adhesion G protein-coupled receptor G4b
chr16_+_6021908 1.22 ENSDART00000163786
BX511115.1

chr15_+_1796313 1.22 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr24_-_38657683 1.21 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr15_-_21877726 1.21 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr20_-_1176631 1.20 ENSDART00000152255
gabrr2b
gamma-aminobutyric acid (GABA) A receptor, rho 2b
chr21_+_6751760 1.19 ENSDART00000135914
olfm1b
olfactomedin 1b
chr12_+_30265802 1.18 ENSDART00000182412
afap1l2
actin filament associated protein 1-like 2
chr19_-_7495006 1.18 ENSDART00000148836
rfx5
regulatory factor X, 5
chr6_+_9677420 1.16 ENSDART00000064995
sumo1
small ubiquitin-like modifier 1
chr16_+_41826584 1.16 ENSDART00000147523
si:dkey-199f5.6
si:dkey-199f5.6
chr10_+_6884627 1.14 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr1_-_19502322 1.14 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr11_+_7264457 1.13 ENSDART00000154182
reep6
receptor accessory protein 6
chr20_-_9095105 1.12 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr6_+_6924637 1.10 ENSDART00000065551
ENSDART00000151393
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr4_+_11464255 1.10 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr18_-_43884044 1.10 ENSDART00000087382
ddx6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr2_+_33051730 1.09 ENSDART00000177902
ENSDART00000187903
rnf220a
ring finger protein 220a
chr11_+_33818179 1.08 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr18_+_7639401 1.08 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr4_+_22480169 1.08 ENSDART00000146272
ENSDART00000066904
ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr19_-_31402429 1.07 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr6_+_41191482 1.05 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr12_-_28363111 1.05 ENSDART00000016283
ENSDART00000164156
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr25_+_31267268 1.04 ENSDART00000181239
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr18_-_21950751 1.04 ENSDART00000043452
tsnaxip1
translin-associated factor X interacting protein 1
chr20_-_48470599 1.04 ENSDART00000166857
CABZ01059120.1

chr16_-_42933332 1.01 ENSDART00000057305
thbs3a
thrombospondin 3a
chr23_+_26979174 0.99 ENSDART00000018654
rnd1b
Rho family GTPase 1b
chr16_-_51271962 0.99 ENSDART00000164021
ENSDART00000046420
serpinb1l1
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr23_+_20110086 0.98 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr15_-_22074315 0.97 ENSDART00000149830
drd2a
dopamine receptor D2a
chr21_+_45841731 0.97 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr15_-_35252522 0.96 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr11_-_2131280 0.95 ENSDART00000008409
calcoco1b
calcium binding and coiled-coil domain 1b
chr3_+_29445473 0.94 ENSDART00000020381
grap2a
GRB2-related adaptor protein 2a
chr8_+_20776654 0.93 ENSDART00000135850
nfic
nuclear factor I/C
chr18_+_14529005 0.93 ENSDART00000186379
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr24_+_12133814 0.93 ENSDART00000158562
ENSDART00000159029
ENSDART00000168248
lztfl1
leucine zipper transcription factor-like 1
chr6_-_40832245 0.92 ENSDART00000007783
eefsec
eukaryotic elongation factor, selenocysteine-tRNA-specific
chr9_-_813511 0.90 ENSDART00000082368
marco
macrophage receptor with collagenous structure
chr3_+_59784632 0.89 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr9_-_53666031 0.89 ENSDART00000126314
pcdh8
protocadherin 8
chr1_-_50859053 0.89 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr13_-_36663358 0.88 ENSDART00000085319
sos2
son of sevenless homolog 2 (Drosophila)
chr25_+_20715950 0.87 ENSDART00000180223
ergic2
ERGIC and golgi 2
chr10_+_42690374 0.87 ENSDART00000123496
rhobtb2b
Rho-related BTB domain containing 2b
chr18_+_5137241 0.86 ENSDART00000159601
serpini1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr4_+_74929427 0.86 ENSDART00000174082
nup50
nucleoporin 50
chr15_+_41027466 0.85 ENSDART00000075940
mtnr1ba
melatonin receptor type 1Ba
chr19_-_5103313 0.85 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr9_-_22834860 0.85 ENSDART00000146486
neb
nebulin
chr14_-_7137808 0.85 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr13_+_22295905 0.84 ENSDART00000180133
ENSDART00000181125
usp54a
ubiquitin specific peptidase 54a
chr23_-_16485190 0.84 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr11_+_25129013 0.84 ENSDART00000132879
ndrg3a
ndrg family member 3a
chr4_+_76575585 0.83 ENSDART00000131588
ms4a17a.11
membrane-spanning 4-domains, subfamily A, member 17A.11
chr23_+_40460333 0.82 ENSDART00000184658
soga3b
SOGA family member 3b
chr20_-_47188966 0.81 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr5_+_40485503 0.81 ENSDART00000051055
ndufs4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, (NADH-coenzyme Q reductase)
chr22_-_15578402 0.79 ENSDART00000062986
hsh2d
hematopoietic SH2 domain containing
chr19_-_5103141 0.79 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr6_-_30210378 0.77 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr2_+_6963296 0.76 ENSDART00000147146
ddr2b
discoidin domain receptor tyrosine kinase 2b
chr4_+_58576146 0.76 ENSDART00000164911
si:ch211-212k5.4
si:ch211-212k5.4
chr3_+_32112004 0.75 ENSDART00000105272
zgc:173593
zgc:173593
chr4_+_71989418 0.75 ENSDART00000170996
parp11
poly(ADP-ribose) polymerase family member 11
chr20_+_46513651 0.75 ENSDART00000152977
zc3h14
zinc finger CCCH-type containing 14
chr11_-_41853874 0.74 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr19_-_29853402 0.73 ENSDART00000024292
ENSDART00000188508
txlna
taxilin alpha
chr18_+_17827149 0.73 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr14_-_40390757 0.73 ENSDART00000149443
pcdh19
protocadherin 19
chr12_+_5977777 0.72 ENSDART00000152302
si:ch211-131k2.2
si:ch211-131k2.2
chr24_-_31425799 0.72 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr8_+_52637507 0.72 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr11_+_38280454 0.71 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr4_+_47636303 0.71 ENSDART00000167272
ENSDART00000166961
BX324142.1

chr18_+_11506561 0.71 ENSDART00000121647
PRMT8
protein arginine methyltransferase 8
chr16_-_31754102 0.71 ENSDART00000185043
ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr15_+_23799461 0.70 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr13_+_35339182 0.69 ENSDART00000019323
jag1b
jagged 1b
chr8_+_52619365 0.69 ENSDART00000162953
cyr61l2
cysteine-rich, angiogenic inducer, 61 like 2
chr14_-_4145594 0.69 ENSDART00000077348
casp3b
caspase 3, apoptosis-related cysteine peptidase b
chr22_-_8388678 0.69 ENSDART00000184389
CABZ01061498.1

chr4_-_948776 0.69 ENSDART00000023483
sim1b
single-minded family bHLH transcription factor 1b
chr4_+_77943184 0.67 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr3_-_30625219 0.67 ENSDART00000151698
syt3
synaptotagmin III
chr15_+_47492838 0.65 ENSDART00000122372
sik3
SIK family kinase 3
chr9_-_6372535 0.64 ENSDART00000149189
ecrg4a
esophageal cancer related gene 4a
chr3_-_60827402 0.64 ENSDART00000053494
anks4b
ankyrin repeat and sterile alpha motif domain containing 4B
chr23_-_31512496 0.63 ENSDART00000158755
ENSDART00000143425
eya4
EYA transcriptional coactivator and phosphatase 4
chr23_+_44374041 0.63 ENSDART00000136056
ephb4b
eph receptor B4b
chr21_-_37790727 0.63 ENSDART00000162907
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr18_-_46258612 0.62 ENSDART00000153930
si:dkey-244a7.1
si:dkey-244a7.1
chr18_-_2433011 0.61 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr17_-_3815693 0.61 ENSDART00000161207
PLCB4
phospholipase C beta 4
chr25_+_29160102 0.61 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr14_+_11458044 0.61 ENSDART00000186425
si:ch211-153b23.5
si:ch211-153b23.5
chr5_-_69649044 0.60 ENSDART00000011192
ENSDART00000170885
eif2b1
eukaryotic translation initiation factor 2B, subunit 1 alpha
chr1_-_14332283 0.59 ENSDART00000090025
wfs1a
Wolfram syndrome 1a (wolframin)
chr19_-_38611814 0.58 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr25_-_31953516 0.57 ENSDART00000110180
duox2
dual oxidase 2
chr19_+_5543072 0.56 ENSDART00000082080
jupb
junction plakoglobin b
chr21_-_26490186 0.55 ENSDART00000009889
zgc:110540
zgc:110540
chr24_-_6078222 0.55 ENSDART00000146830
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr15_+_44366556 0.54 ENSDART00000133449
GUCY1A2
guanylate cyclase 1 soluble subunit alpha 2
chr8_+_29986265 0.54 ENSDART00000148258
ptch1
patched 1
chr11_-_15296805 0.54 ENSDART00000124968
rpn2
ribophorin II
chr22_-_209741 0.53 ENSDART00000171954
ora1
olfactory receptor class A related 1
chr5_+_9147497 0.53 ENSDART00000003273
rchy1
ring finger and CHY zinc finger domain containing 1
chr5_+_66433287 0.52 ENSDART00000170757
kntc1
kinetochore associated 1
chr3_-_7546740 0.52 ENSDART00000128960
zmp:0000001003
zmp:0000001003
chr4_-_55459037 0.52 ENSDART00000172184
znf569l
zinc finger protein 569, like
chr18_+_48423973 0.51 ENSDART00000184233
ENSDART00000147074
fli1a
Fli-1 proto-oncogene, ETS transcription factor a
chr6_-_40884453 0.50 ENSDART00000017968
ENSDART00000154100
sirt4
sirtuin 4
chr21_+_18997511 0.49 ENSDART00000145591
rpl17
ribosomal protein L17
chr22_-_36530902 0.48 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr18_+_23408073 0.47 ENSDART00000136489
mctp2a
multiple C2 domains, transmembrane 2a
chr20_+_35382482 0.47 ENSDART00000135284
vsnl1a
visinin-like 1a
chr18_-_502722 0.47 ENSDART00000185757
sdr42e1
short chain dehydrogenase/reductase family 42E, member 1

Network of associatons between targets according to the STRING database.

First level regulatory network of gsx2+pnx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.5 1.6 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.5 6.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.5 1.9 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.4 3.0 GO:0070207 protein homotrimerization(GO:0070207)
0.4 1.6 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.4 1.2 GO:0032637 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.4 1.5 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.4 1.9 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.3 2.6 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.3 6.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 1.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.3 0.9 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.3 1.2 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.3 1.1 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 0.7 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 1.2 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 0.6 GO:0070314 G1 to G0 transition(GO:0070314)
0.2 1.5 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 1.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 1.0 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.2 1.9 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.2 4.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.8 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 1.1 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.1 GO:0034063 stress granule assembly(GO:0034063)
0.1 1.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 2.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.6 GO:0002159 desmosome assembly(GO:0002159)
0.1 1.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 2.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.6 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 1.9 GO:0006415 translational termination(GO:0006415)
0.1 1.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.9 GO:1903828 negative regulation of cellular protein localization(GO:1903828)
0.1 1.9 GO:0021984 adenohypophysis development(GO:0021984)
0.1 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.1 GO:0032418 lysosome localization(GO:0032418)
0.1 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 2.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.0 GO:0043248 proteasome assembly(GO:0043248)
0.1 3.8 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.7 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 1.1 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 1.3 GO:0015671 oxygen transport(GO:0015671)
0.1 0.5 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 5.0 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.1 1.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.1 1.8 GO:0042073 intraciliary transport(GO:0042073)
0.1 0.2 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.3 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.3 GO:0098586 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.1 0.8 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.5 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:0036268 swimming(GO:0036268)
0.1 0.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.5 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.7 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 1.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.1 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 1.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.4 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 2.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 1.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 2.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.7 GO:0048854 brain morphogenesis(GO:0048854)
0.0 0.4 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 5.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839) negative regulation of nuclear division(GO:0051784)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.5 GO:0046474 glycerophospholipid biosynthetic process(GO:0046474)
0.0 1.4 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.8 GO:0022900 electron transport chain(GO:0022900)
0.0 1.6 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.9 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.7 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.9 GO:0006694 steroid biosynthetic process(GO:0006694)
0.0 0.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 6.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.3 4.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 1.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.2 GO:0042627 chylomicron(GO:0042627)
0.1 6.6 GO:0031514 motile cilium(GO:0031514)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.9 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 3.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 4.4 GO:0005930 axoneme(GO:0005930)
0.1 1.5 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.7 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.8 GO:0005861 troponin complex(GO:0005861)
0.0 1.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.1 GO:0043186 P granule(GO:0043186)
0.0 0.2 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.8 GO:0005604 collagen trimer(GO:0005581) basement membrane(GO:0005604)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 1.1 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 1.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.9 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 2.0 GO:0030018 Z disc(GO:0030018)
0.0 2.6 GO:0005840 ribosome(GO:0005840)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.5 1.6 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.4 1.6 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.4 1.5 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.4 1.9 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.4 1.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.3 4.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.7 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.2 1.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.2 1.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 1.9 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 2.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.5 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.9 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.0 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 1.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 2.6 GO:0043236 laminin binding(GO:0043236)
0.1 1.3 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.8 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 1.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.1 1.2 GO:0031386 protein tag(GO:0031386)
0.1 2.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 3.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.7 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 1.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 1.8 GO:0019843 rRNA binding(GO:0019843)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.5 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.7 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 2.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0051020 GTPase binding(GO:0051020)
0.0 1.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 6.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 1.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 5.3 GO:0003924 GTPase activity(GO:0003924)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.8 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.5 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 4.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.9 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 2.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.1 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.4 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions