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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for hmbox1a+zgc:91944
Z-value: 0.40
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Transcription factors associated with hmbox1a+zgc:91944
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hmbox1a | dr11_v1_chr17_-_16324565_16324565 | 0.84 | 1.6e-05 | Click! |
| CABZ01078261.1 | dr11_v1_chr20_+_49787584_49787584 | 0.75 | 3.4e-04 | Click! |
| zgc:91944 | dr11_v1_chr19_-_32600823_32600868 | -0.30 | 2.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_35191220 Show fit | 0.63 |
ENSDART00000110552
|
zinc finger, DHHC-type containing 1 |
|
| chr18_+_35130416 Show fit | 0.59 |
ENSDART00000151595
|
si:ch211-195m9.3 |
|
| chr2_-_21438492 Show fit | 0.54 |
ENSDART00000046098
|
phospholipase C, delta 1b |
|
| chr10_+_7709724 Show fit | 0.52 |
ENSDART00000097670
|
gamma-glutamyl carboxylase |
|
| chr17_+_21902058 Show fit | 0.52 |
ENSDART00000142178
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a |
|
| chr13_-_21672131 Show fit | 0.46 |
ENSDART00000067537
|
ELOVL family member 6, elongation of long chain fatty acids like |
|
| chr2_-_27619954 Show fit | 0.45 |
ENSDART00000144826
|
trimethylguanosine synthase 1 |
|
| chr7_+_36467796 Show fit | 0.43 |
ENSDART00000146202
|
akt interacting protein |
|
| chr15_-_1036878 Show fit | 0.41 |
ENSDART00000123844
|
si:dkey-77f5.3 |
|
| chr17_-_11368662 Show fit | 0.38 |
ENSDART00000159061
ENSDART00000188694 ENSDART00000190932 |
si:ch211-185a18.2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of hmbox1a+zgc:91944
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 0.5 | GO:0017187 | peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214) |
| 0.0 | 0.4 | GO:0050435 | beta-amyloid metabolic process(GO:0050435) |
| 0.0 | 0.4 | GO:0098927 | early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927) |
| 0.0 | 0.4 | GO:0034625 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.0 | 0.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.4 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 0.1 | 0.3 | GO:0031335 | regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666) |
| 0.1 | 0.3 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.1 | 0.3 | GO:0015990 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.4 | GO:0001401 | mitochondrial sorting and assembly machinery complex(GO:0001401) |
| 0.0 | 0.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 0.3 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 0.1 | 0.3 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.1 | 0.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 0.3 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 0.3 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.1 | 0.2 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 0.1 | 0.2 | GO:0044279 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 0.5 | GO:0008488 | gamma-glutamyl carboxylase activity(GO:0008488) |
| 0.0 | 0.5 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.5 | GO:0004629 | phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629) |
| 0.0 | 0.4 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 0.4 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.0 | 0.4 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.3 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.1 | 0.3 | GO:0031956 | medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760) |
| 0.1 | 0.3 | GO:0008905 | mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.3 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.4 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.0 | 0.4 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.3 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.3 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.3 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |