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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hnf1a

Z-value: 0.63

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Transcription factors associated with hnf1a

Gene Symbol Gene ID Gene Info
hnf1a
ENSDARG00000009470 HNF1 homeobox a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf1adr11_v1_chr8_+_39802506_39802506-0.401.0e-01Click!

Activity profile of hnf1a motif

Sorted Z-values of hnf1a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_35066457 2.44 ENSDART00000058067
zgc:112160
zgc:112160
chr24_-_39610585 2.40 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr24_-_4765740 2.15 ENSDART00000121576
cpb1
carboxypeptidase B1 (tissue)
chr3_+_31039923 1.97 ENSDART00000147706
cox6a2
cytochrome c oxidase subunit VIa polypeptide 2
chr7_-_10560964 1.83 ENSDART00000172761
ENSDART00000170476
mthfs
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
chr5_+_13385837 1.67 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr16_-_42894628 1.67 ENSDART00000045600
hfe2
hemochromatosis type 2
chr11_-_37997419 1.66 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr24_+_26345427 1.54 ENSDART00000089756
lrrc34
leucine rich repeat containing 34
chr20_+_18741089 1.38 ENSDART00000183218
fam167ab
family with sequence similarity 167, member Ab
chr5_-_30715225 1.32 ENSDART00000016758
ftr82
finTRIM family, member 82
chr7_-_25126212 1.23 ENSDART00000173588
MAJIN
si:dkey-23i12.11
chr3_-_16250527 1.13 ENSDART00000146699
ENSDART00000141181
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr24_+_26345609 1.11 ENSDART00000186844
lrrc34
leucine rich repeat containing 34
chr2_-_17828279 1.10 ENSDART00000083314
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr8_+_26522013 1.08 ENSDART00000046863
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr2_+_26647472 1.02 ENSDART00000145415
ENSDART00000157409
ttpa
tocopherol (alpha) transfer protein
chr21_+_38002879 1.01 ENSDART00000065183
cldn2
claudin 2
chr3_+_26734162 1.00 ENSDART00000114552
si:dkey-202l16.5
si:dkey-202l16.5
chr4_+_7827261 1.00 ENSDART00000129568
phyh
phytanoyl-CoA 2-hydroxylase
chr21_-_45920 0.97 ENSDART00000040422
bhmt
betaine-homocysteine methyltransferase
chr1_+_10051763 0.96 ENSDART00000011701
fgb
fibrinogen beta chain
chr12_+_47044707 0.84 ENSDART00000186506
zranb1a
zinc finger, RAN-binding domain containing 1a
chr1_-_22851481 0.84 ENSDART00000054386
qdprb1
quinoid dihydropteridine reductase b1
chr21_+_37442458 0.82 ENSDART00000180161
ENSDART00000186950
cox7b
cytochrome c oxidase subunit VIIb
chr12_-_20373058 0.79 ENSDART00000066382
aqp8a.1
aquaporin 8a, tandem duplicate 1
chr1_-_19502322 0.79 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr22_-_36750589 0.79 ENSDART00000010824
acy1
aminoacylase 1
chr3_+_15505275 0.77 ENSDART00000141714
nupr1
nuclear protein 1
chr3_-_53092509 0.76 ENSDART00000062081
lpar2a
lysophosphatidic acid receptor 2a
chr12_+_35067863 0.76 ENSDART00000152849
syt15
synaptotagmin XV
chr10_-_41664427 0.75 ENSDART00000150213
ggt1b
gamma-glutamyltransferase 1b
chr10_+_2981090 0.74 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr25_-_37191929 0.70 ENSDART00000128108
urahb
urate (5-hydroxyiso-) hydrolase b
chr4_-_9533345 0.64 ENSDART00000128501
si:ch73-139j3.4
si:ch73-139j3.4
chr25_+_34915576 0.63 ENSDART00000073441
sntb2
syntrophin, beta 2
chr18_+_3530769 0.63 ENSDART00000163469
si:ch73-338a16.3
si:ch73-338a16.3
chr22_+_38978084 0.61 ENSDART00000025482
arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr25_+_34915762 0.59 ENSDART00000191776
sntb2
syntrophin, beta 2
chr5_+_9428876 0.59 ENSDART00000081791
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr3_-_53091946 0.58 ENSDART00000187297
lpar2a
lysophosphatidic acid receptor 2a
chr22_-_17595310 0.57 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr3_-_41535647 0.56 ENSDART00000153723
ENSDART00000154198
si:ch211-222n22.1
si:ch211-222n22.1
chr11_+_43419809 0.55 ENSDART00000172982
slc29a1b
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr7_-_59564011 0.55 ENSDART00000186053
zgc:112271
zgc:112271
chr3_+_13559199 0.54 ENSDART00000166547
si:ch73-106n3.1
si:ch73-106n3.1
chr21_+_10076203 0.52 ENSDART00000190383
CABZ01043506.1

chr7_-_25895189 0.51 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
cd99l2
CD99 molecule-like 2
chr8_+_7144066 0.50 ENSDART00000146306
slc6a6a
solute carrier family 6 (neurotransmitter transporter), member 6a
chr9_+_28688574 0.50 ENSDART00000101319
zgc:162396
zgc:162396
chr20_+_22666548 0.50 ENSDART00000147520
lnx1
ligand of numb-protein X 1
chr18_-_5111449 0.49 ENSDART00000046902
pdcd10a
programmed cell death 10a
chr8_+_999421 0.49 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr2_-_127945 0.49 ENSDART00000056453
igfbp1b
insulin-like growth factor binding protein 1b
chr17_+_4030493 0.47 ENSDART00000151849
hao1
hydroxyacid oxidase (glycolate oxidase) 1
chr20_-_47347962 0.47 ENSDART00000080863
dtnba
dystrobrevin, beta a
chr25_+_7670683 0.46 ENSDART00000040275
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr8_-_47800754 0.45 ENSDART00000115050
ENSDART00000133669
kank3
KN motif and ankyrin repeat domains 3
chr5_+_45677781 0.45 ENSDART00000163120
ENSDART00000126537
gc
group-specific component (vitamin D binding protein)
chr20_+_18740518 0.44 ENSDART00000142196
fam167ab
family with sequence similarity 167, member Ab
chr4_+_18804317 0.43 ENSDART00000101043
slc26a3.2
solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2
chr25_+_31323978 0.41 ENSDART00000067030
lsp1
lymphocyte-specific protein 1
chr20_+_10544100 0.41 ENSDART00000113927
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr20_-_47348116 0.41 ENSDART00000162087
ENSDART00000160769
ENSDART00000164484
dtnba
dystrobrevin, beta a
chr5_+_32345187 0.41 ENSDART00000147132
c9
complement component 9
chr13_-_40726865 0.41 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr12_-_28848015 0.40 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr25_+_23280220 0.39 ENSDART00000153940
ptprjb.1
protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1
chr1_+_22851261 0.39 ENSDART00000193925
gtf2e2
general transcription factor IIE, polypeptide 2, beta
chr24_+_23791758 0.39 ENSDART00000066655
ENSDART00000146580
mybl1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr15_-_17869115 0.38 ENSDART00000112838
atf5b
activating transcription factor 5b
chr22_-_17611742 0.38 ENSDART00000144031
gpx4a
glutathione peroxidase 4a
chr4_+_57881965 0.38 ENSDART00000162234
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr22_-_23625351 0.37 ENSDART00000192588
ENSDART00000163423
cfhl4
complement factor H like 4
chr16_+_11724230 0.36 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr10_+_2899108 0.36 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr1_-_59348118 0.35 ENSDART00000170901
cyp3a65
cytochrome P450, family 3, subfamily A, polypeptide 65
chr22_-_23748284 0.35 ENSDART00000162005
cfhl2
complement factor H like 2
chr24_-_3304664 0.35 ENSDART00000183168
sugct
succinyl-CoA:glutarate-CoA transferase
chr22_-_26005894 0.35 ENSDART00000105088
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr20_+_18740799 0.34 ENSDART00000174532
fam167ab
family with sequence similarity 167, member Ab
chr24_-_23675446 0.34 ENSDART00000066644
hnf4g
hepatocyte nuclear factor 4, gamma
chr5_-_29488245 0.34 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
cacna1ba
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr9_+_29994439 0.33 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr7_+_27250186 0.32 ENSDART00000150068
sox6
SRY (sex determining region Y)-box 6
chr19_+_24882845 0.32 ENSDART00000010580
si:ch211-195b13.1
si:ch211-195b13.1
chr22_-_23668356 0.31 ENSDART00000167106
ENSDART00000159622
ENSDART00000163228
cfh
complement factor H
chr14_-_41556720 0.31 ENSDART00000149244
itga6l
integrin, alpha 6, like
chr15_+_27364394 0.31 ENSDART00000122101
tbx2b
T-box 2b
chr6_+_41039166 0.31 ENSDART00000125659
entpd8
ectonucleoside triphosphate diphosphohydrolase 8
chr8_+_1187928 0.30 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr14_+_8504410 0.29 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
chr1_-_9134045 0.29 ENSDART00000142132
palb2
partner and localizer of BRCA2
chr13_-_23666579 0.28 ENSDART00000192457
ENSDART00000179777
map3k21
mitogen-activated protein kinase kinase kinase 21
chr24_-_17039638 0.27 ENSDART00000048823
c8g
complement component 8, gamma polypeptide
chr5_+_21225017 0.27 ENSDART00000141573
si:dkey-13n15.11
si:dkey-13n15.11
chr20_-_43723860 0.27 ENSDART00000122051
mixl1
Mix paired-like homeobox
chr5_+_28830643 0.27 ENSDART00000051448
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr22_-_26100282 0.26 ENSDART00000166075
pdgfaa
platelet-derived growth factor alpha polypeptide a
chr21_-_23308286 0.26 ENSDART00000184419
zbtb16a
zinc finger and BTB domain containing 16a
chr4_+_76416268 0.26 ENSDART00000174351
ENSDART00000191591
zgc:113209
FP074874.1
zgc:113209

chr20_+_6543674 0.26 ENSDART00000134204
tns3.1
tensin 3, tandem duplicate 1
chr13_-_42579437 0.25 ENSDART00000135172
fam83ha
family with sequence similarity 83, member Ha
chr3_-_18047150 0.25 ENSDART00000020376
hsd17b1
hydroxysteroid (17-beta) dehydrogenase 1
chr6_-_59563597 0.25 ENSDART00000166311
INHBE
inhibin beta E subunit
chr6_+_40723554 0.25 ENSDART00000103833
slc26a6l
solute carrier family 26, member 6, like
chr5_-_67783593 0.25 ENSDART00000010934
casr
calcium-sensing receptor
chr21_+_44684577 0.24 ENSDART00000099528
spry4
sprouty homolog 4 (Drosophila)
chr19_+_20274944 0.24 ENSDART00000151237
oxnad1
oxidoreductase NAD-binding domain containing 1
chr20_+_41756996 0.24 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr3_+_54761569 0.23 ENSDART00000135913
ENSDART00000180983
si:ch211-74m13.1
si:ch211-74m13.1
chr3_+_40170216 0.23 ENSDART00000011568
syngr3a
synaptogyrin 3a
chr25_-_13490744 0.22 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr20_+_35473288 0.22 ENSDART00000047195
mep1a.1
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 1
chr10_+_7255695 0.22 ENSDART00000161506
ENSDART00000181304
fut10
fucosyltransferase 10
chr14_-_32884138 0.22 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr7_-_29625509 0.21 ENSDART00000173723
rorab
RAR-related orphan receptor A, paralog b
chr13_+_23988442 0.20 ENSDART00000010918
agt
angiotensinogen
chr20_-_25436389 0.20 ENSDART00000153266
itsn2a
intersectin 2a
chr20_-_42534504 0.20 ENSDART00000132310
rfx6
regulatory factor X, 6
chr6_+_7977611 0.19 ENSDART00000112290
palm3
paralemmin 3
chr6_+_30456788 0.19 ENSDART00000121492
FP236735.1

chr6_-_39344259 0.19 ENSDART00000104074
zgc:158846
zgc:158846
chr5_+_9348284 0.19 ENSDART00000149417
tal2
T-cell acute lymphocytic leukemia 2
chr8_-_13013123 0.19 ENSDART00000147802
dennd2da
DENN/MADD domain containing 2Da
chr22_+_12770877 0.18 ENSDART00000044683
ftcd
formimidoyltransferase cyclodeaminase
chr10_+_21867307 0.18 ENSDART00000126629
cbln17
cerebellin 17
chr11_+_25129013 0.18 ENSDART00000132879
ndrg3a
ndrg family member 3a
chr18_+_17786548 0.18 ENSDART00000189493
ENSDART00000146133
ZNF423
si:ch211-216l23.1
chr2_-_24402341 0.18 ENSDART00000155442
ENSDART00000088572
zgc:154006
zgc:154006
chr24_+_14713776 0.18 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr3_-_34337969 0.16 ENSDART00000151634
tnrc6c1
trinucleotide repeat containing 6C1
chr9_+_4429593 0.16 ENSDART00000184855
FP015810.1

chr10_-_8032885 0.15 ENSDART00000188619
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr2_+_17055069 0.15 ENSDART00000115078
thpo
thrombopoietin
chr8_-_40555340 0.15 ENSDART00000163348
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr5_+_9382301 0.14 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr2_-_27609189 0.14 ENSDART00000040555
lyn
LYN proto-oncogene, Src family tyrosine kinase
chr7_-_29534001 0.14 ENSDART00000124028
anxa2b
annexin A2b
chr10_-_8033468 0.14 ENSDART00000140476
atp6v0a2a
ATPase H+ transporting V0 subunit a2a
chr4_+_45484774 0.14 ENSDART00000150573
si:dkey-256i11.6
si:dkey-256i11.6
chr12_-_6172154 0.13 ENSDART00000185434
a1cf
apobec1 complementation factor
chr6_+_54221654 0.13 ENSDART00000128456
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr5_+_26795773 0.13 ENSDART00000145631
tcn2
transcobalamin II
chr17_-_7371564 0.13 ENSDART00000060336
rab32b
RAB32b, member RAS oncogene family
chr11_-_6069081 0.12 ENSDART00000008980
babam1
BRISC and BRCA1 A complex member 1
chr5_+_28830388 0.12 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_+_49521106 0.12 ENSDART00000162799
crb3a
crumbs homolog 3a
chr15_+_35139457 0.11 ENSDART00000059204
slc19a3a
solute carrier family 19 (thiamine transporter), member 3a
chr6_-_49078702 0.11 ENSDART00000135185
slc5a8l
solute carrier family 5 (iodide transporter), member 8-like
chr6_+_28141135 0.11 ENSDART00000113405
ENSDART00000179795
inpp5d
inositol polyphosphate-5-phosphatase D
chr10_+_20108557 0.11 ENSDART00000142708
dmtn
dematin actin binding protein
chr12_+_5209822 0.11 ENSDART00000152610
SLC35G1
si:ch211-197g18.2
chr15_-_17868870 0.11 ENSDART00000170950
atf5b
activating transcription factor 5b
chr17_+_15033822 0.11 ENSDART00000154987
samd4a
sterile alpha motif domain containing 4A
chr22_-_24818066 0.11 ENSDART00000143443
vtg6
vitellogenin 6
chr2_-_41942666 0.11 ENSDART00000075673
ebi3
Epstein-Barr virus induced 3
chr6_+_8622228 0.11 ENSDART00000110470
tspeara
thrombospondin-type laminin G domain and EAR repeats a
chr12_+_2648043 0.10 ENSDART00000082220
gdf2
growth differentiation factor 2
chr12_-_6177894 0.10 ENSDART00000152292
a1cf
apobec1 complementation factor
chr5_+_45322734 0.10 ENSDART00000084411
adamts3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr22_-_27113332 0.10 ENSDART00000146951
ENSDART00000178855
xpnpep1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr5_+_9377005 0.10 ENSDART00000124924
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr17_+_43595692 0.10 ENSDART00000156271
cfap99
cilia and flagella associated protein 99
chr19_-_22387141 0.09 ENSDART00000151234
eppk1
epiplakin 1
chr20_-_40750953 0.09 ENSDART00000061256
cx28.9
connexin 28.9
chr1_+_26667872 0.09 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemgn
hemogen
chr16_+_55059026 0.08 ENSDART00000109391
LO017815.1
Danio rerio nuclear receptor coactivator 7-like (LOC792958), mRNA.
chr21_+_43669943 0.08 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr20_-_7293837 0.08 ENSDART00000100060
dsc2l
desmocollin 2 like
chr14_-_17622080 0.08 ENSDART00000112149
si:ch211-159i8.4
si:ch211-159i8.4
chr2_-_10821053 0.07 ENSDART00000056034
rpap2
RNA polymerase II associated protein 2
chr10_+_4499943 0.07 ENSDART00000125299
plk2a
polo-like kinase 2a (Drosophila)
chr16_+_4138331 0.07 ENSDART00000192403
ENSDART00000193036
mtf1
metal-regulatory transcription factor 1
chr5_+_9417409 0.05 ENSDART00000125421
ENSDART00000130265
ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr9_-_9977827 0.05 ENSDART00000187315
ENSDART00000010246
ugt1ab
UDP glucuronosyltransferase 1 family a, b
chr6_+_28140816 0.05 ENSDART00000137907
inpp5d
inositol polyphosphate-5-phosphatase D
chr16_+_34531486 0.05 ENSDART00000043291
paqr7b
progestin and adipoQ receptor family member VII, b
chr18_+_13182528 0.04 ENSDART00000166298
zgc:56622
zgc:56622
chr4_-_32642681 0.04 ENSDART00000188695
ENSDART00000193974
si:dkey-265e7.1
si:dkey-265e7.1
chr21_+_40092301 0.04 ENSDART00000145150
serpinf2a
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr11_-_6068375 0.04 ENSDART00000167672
ENSDART00000122262
babam1
BRISC and BRCA1 A complex member 1
chr5_+_1877464 0.04 ENSDART00000050658
zgc:101699
zgc:101699
chr23_-_20345473 0.04 ENSDART00000140935
si:rp71-17i16.6
si:rp71-17i16.6
chr22_+_29135846 0.03 ENSDART00000143811
baiap2l2b
BAI1-associated protein 2-like 2b
chr19_+_31043002 0.03 ENSDART00000171591
ankmy2b
ankyrin repeat and MYND domain containing 2b
chr15_+_29283981 0.03 ENSDART00000099895
rap1gap2a
RAP1 GTPase activating protein 2a
chr14_-_41556533 0.03 ENSDART00000074401
itga6l
integrin, alpha 6, like
chr5_-_56513825 0.03 ENSDART00000024207
tbx2a
T-box 2a
chr4_+_2620751 0.03 ENSDART00000013924
gpr22a
G protein-coupled receptor 22a
chr12_+_31673588 0.03 ENSDART00000152971
dnmbp
dynamin binding protein
chr5_-_30620625 0.02 ENSDART00000098273
tcnl
transcobalamin like
chr2_-_23778180 0.02 ENSDART00000136782
si:dkey-24c2.7
si:dkey-24c2.7
chr9_-_14108896 0.02 ENSDART00000135209
prkag3b
protein kinase, AMP-activated, gamma 3b non-catalytic subunit
chr16_-_29403711 0.02 ENSDART00000175571
tlr18
toll-like receptor 18
chr17_+_15388479 0.02 ENSDART00000052439
si:ch211-266g18.6
si:ch211-266g18.6
chr22_-_36770649 0.02 ENSDART00000169442
acy1
aminoacylase 1
chr23_+_32335871 0.02 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr16_+_11623956 0.02 ENSDART00000137788
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr12_+_15666949 0.02 ENSDART00000079803
nmt1b
N-myristoyltransferase 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 1.8 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 1.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 0.8 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 0.8 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 0.5 GO:1903358 regulation of Golgi organization(GO:1903358)
0.2 1.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.2 2.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.6 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.1 0.3 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.1 0.8 GO:0031179 peptide modification(GO:0031179)
0.1 0.6 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 1.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.2 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 1.0 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 0.2 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 1.7 GO:0051180 vitamin transport(GO:0051180)
0.1 0.2 GO:0015867 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.9 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0044320 leptin-mediated signaling pathway(GO:0033210) cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.4 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.7 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.3 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.2 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 2.3 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.2 GO:0072425 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.6 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.4 GO:0043407 negative regulation of MAP kinase activity(GO:0043407) artery morphogenesis(GO:0048844)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.8 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.3 GO:0043507 activation of JUN kinase activity(GO:0007257) regulation of JUN kinase activity(GO:0043506) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.8 GO:0050922 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.2 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.5 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.2 2.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.4 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 2.8 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 1.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0015250 water channel activity(GO:0015250)
0.1 0.8 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.1 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.5 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 1.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 1.8 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.5 GO:1901682 sulfur compound transmembrane transporter activity(GO:1901682)
0.0 1.0 GO:0019842 vitamin binding(GO:0019842)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.3 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.0 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 1.1 GO:0008201 heparin binding(GO:0008201)
0.0 2.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID BMP PATHWAY BMP receptor signaling
0.1 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules