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PRJNA438478: RNAseq of wild type zebrafish germline
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Results for hnf4g
Z-value: 1.29
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Transcription factors associated with hnf4g
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hnf4g | dr11_v1_chr24_-_23671709_23671709 | -0.79 | 9.8e-05 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_2590222 Show fit | 7.22 |
ENSDART00000185711
|
|
|
| chr17_-_2573021 Show fit | 6.13 |
ENSDART00000074181
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2578026 Show fit | 6.02 |
ENSDART00000065821
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2595736 Show fit | 5.62 |
ENSDART00000128797
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2584423 Show fit | 5.57 |
ENSDART00000013506
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr4_-_77114795 Show fit | 5.50 |
ENSDART00000144849
|
|
|
| chr10_+_19569052 Show fit | 5.39 |
ENSDART00000058425
|
|
|
| chr9_+_8380728 Show fit | 5.03 |
ENSDART00000133501
|
si:ch1073-75o15.4 |
|
| chr22_-_24992532 Show fit | 2.90 |
ENSDART00000102751
|
si:dkey-179j5.5 |
|
| chr16_+_26846495 Show fit | 2.81 |
ENSDART00000078124
|
tripartite motif containing 35-29 |
Network of associatons between targets according to the STRING database.
First level regulatory network of hnf4g
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 23.4 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.1 | 2.5 | GO:0060841 | venous blood vessel development(GO:0060841) |
| 0.3 | 2.4 | GO:0033206 | meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) |
| 0.2 | 1.7 | GO:0046247 | carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247) |
| 0.1 | 1.5 | GO:0051452 | vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452) |
| 0.1 | 1.5 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 1.5 | GO:0002183 | cytoplasmic translational initiation(GO:0002183) |
| 0.0 | 1.4 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.4 | 1.3 | GO:0018872 | arsonoacetate metabolic process(GO:0018872) |
| 0.1 | 1.2 | GO:0071850 | mitotic cell cycle arrest(GO:0071850) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 23.4 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 3.2 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
| 0.0 | 2.5 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.2 | 1.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.2 | 1.2 | GO:0033557 | Slx1-Slx4 complex(GO:0033557) |
| 0.0 | 1.2 | GO:0000922 | spindle pole(GO:0000922) |
| 0.1 | 1.0 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.2 | 0.9 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.0 | 0.9 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.0 | 0.7 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 23.4 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 0.0 | 8.0 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.8 | 2.5 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.0 | 2.2 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.2 | 1.7 | GO:0010436 | beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436) |
| 0.1 | 1.5 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.1 | 1.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 1.5 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.4 | 1.3 | GO:0030791 | arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792) |
| 0.2 | 1.2 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.8 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.0 | 0.8 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.7 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.6 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.3 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.3 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.4 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.1 | 1.0 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.9 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 0.8 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.8 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.0 | 0.7 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 0.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.2 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.1 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |