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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxa11b

Z-value: 1.17

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Transcription factors associated with hoxa11b

Gene Symbol Gene ID Gene Info
hoxa11b
ENSDARG00000007009 homeobox A11b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa11bdr11_v1_chr16_+_20904754_20904754-0.718.6e-04Click!

Activity profile of hoxa11b motif

Sorted Z-values of hoxa11b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_28208973 3.94 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr7_+_1473929 3.89 ENSDART00000050687
lpcat4
lysophosphatidylcholine acyltransferase 4
chr16_+_29509133 3.13 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr23_+_2666944 3.00 ENSDART00000192861
CABZ01057928.1

chr3_-_26184018 2.94 ENSDART00000191604
si:ch211-11k18.4
si:ch211-11k18.4
chr3_-_26183699 2.85 ENSDART00000147517
ENSDART00000140731
si:ch211-11k18.4
si:ch211-11k18.4
chr2_+_16597011 2.80 ENSDART00000160641
ENSDART00000125413
xrn1
5'-3' exoribonuclease 1
chr1_-_6028876 2.69 ENSDART00000168117
si:ch1073-345a8.1
si:ch1073-345a8.1
chr8_+_12951155 2.67 ENSDART00000081601
cept1a
choline/ethanolamine phosphotransferase 1a
chr14_+_32918172 2.64 ENSDART00000182867
lnx2b
ligand of numb-protein X 2b
chr24_-_10014512 2.63 ENSDART00000124341
ENSDART00000191630
zgc:171474
zgc:171474
chr8_+_12118097 2.56 ENSDART00000081819
endog
endonuclease G
chr21_-_19918286 2.53 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr2_-_32738535 2.50 ENSDART00000135293
nrbp2a
nuclear receptor binding protein 2a
chr12_-_4249000 2.25 ENSDART00000059298
zgc:92313
zgc:92313
chr5_+_44805028 2.24 ENSDART00000141198
ctsla
cathepsin La
chr6_+_4528631 2.24 ENSDART00000122042
RNF219
ring finger protein 219
chr14_+_34490445 2.20 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr1_+_494297 2.20 ENSDART00000108579
ENSDART00000146732
blzf1
basic leucine zipper nuclear factor 1
chr5_+_44805269 2.20 ENSDART00000136965
ctsla
cathepsin La
chr19_-_47571456 2.16 ENSDART00000158071
ENSDART00000165841
rrm2
ribonucleotide reductase M2 polypeptide
chr20_-_51831657 2.05 ENSDART00000165076
mia3
melanoma inhibitory activity family, member 3
chr20_-_34028967 2.00 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr20_-_51831816 1.97 ENSDART00000060505
mia3
melanoma inhibitory activity family, member 3
chr13_+_33462232 1.93 ENSDART00000177841
zgc:136302
zgc:136302
chr5_+_3891485 1.92 ENSDART00000129329
ENSDART00000091711
rpain
RPA interacting protein
chr12_-_25887864 1.92 ENSDART00000152983
si:dkey-193p11.2
si:dkey-193p11.2
chr10_-_10969596 1.89 ENSDART00000092011
exd3
exonuclease 3'-5' domain containing 3
chr6_-_9282080 1.88 ENSDART00000159506
ccdc14
coiled-coil domain containing 14
chr21_-_22357545 1.84 ENSDART00000134320
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr8_+_45334255 1.82 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr20_-_49889111 1.81 ENSDART00000058858
kif13bb
kinesin family member 13Bb
chr6_-_42388608 1.81 ENSDART00000049425
sec61a1l
Sec61 translocon alpha 1 subunit, like
chr8_+_21229718 1.78 ENSDART00000100222
cry1ba
cryptochrome circadian clock 1ba
chr19_+_9111550 1.78 ENSDART00000088336
setdb1a
SET domain, bifurcated 1a
chr17_+_14965570 1.77 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr19_-_31042570 1.73 ENSDART00000144337
ENSDART00000136213
ENSDART00000133101
ENSDART00000190949
bzw2
basic leucine zipper and W2 domains 2
chr22_-_11661724 1.72 ENSDART00000025198
mettl21a
methyltransferase like 21A
chr22_+_10713713 1.71 ENSDART00000122349
hiat1b
hippocampus abundant transcript 1b
chr3_+_46763745 1.71 ENSDART00000185437
prkcsh
protein kinase C substrate 80K-H
chr12_+_22674030 1.68 ENSDART00000153254
ENSDART00000152930
cdca9
cell division cycle associated 9
chr16_+_23487051 1.67 ENSDART00000145496
icn2
ictacalcin 2
chr10_-_10969444 1.67 ENSDART00000138041
exd3
exonuclease 3'-5' domain containing 3
chr14_-_33481428 1.65 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr19_-_10915898 1.65 ENSDART00000163179
pip5k1aa
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a
chr12_-_10512911 1.64 ENSDART00000124562
ENSDART00000106163
zgc:152977
zgc:152977
chr11_-_6452444 1.64 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr22_-_10541372 1.62 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr3_-_3366590 1.62 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
si:dkey-46g23.1
chr12_+_16087077 1.61 ENSDART00000141898
znf281b
zinc finger protein 281b
chr25_+_7532627 1.59 ENSDART00000187660
ptdss2
phosphatidylserine synthase 2
chr2_-_44777592 1.57 ENSDART00000113351
ENSDART00000169310
ncapd2
non-SMC condensin I complex, subunit D2
chr4_+_20486041 1.56 ENSDART00000017572
ints13
integrator complex subunit 13
chr14_+_15155684 1.55 ENSDART00000167966
zgc:158852
zgc:158852
chr13_-_2981472 1.55 ENSDART00000184820
CABZ01087623.1

chr20_-_29499363 1.54 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr5_-_1274794 1.53 ENSDART00000167337
ENSDART00000125247
ciz1a
cdkn1a interacting zinc finger protein 1a
chr4_-_20108833 1.50 ENSDART00000100867
fam3c
family with sequence similarity 3, member C
chr19_-_47571797 1.50 ENSDART00000166180
ENSDART00000168134
rrm2
ribonucleotide reductase M2 polypeptide
chr17_-_4245902 1.49 ENSDART00000151851
gdf3
growth differentiation factor 3
chr13_+_36585399 1.46 ENSDART00000030211
gmfb
glia maturation factor, beta
chr7_-_69429561 1.46 ENSDART00000127351
atxn1l
ataxin 1-like
chr3_+_39579393 1.46 ENSDART00000055170
cln3
ceroid-lipofuscinosis, neuronal 3
chr16_-_41717063 1.45 ENSDART00000084610
cep85
centrosomal protein 85
chr13_-_4018888 1.44 ENSDART00000058238
tjap1
tight junction associated protein 1 (peripheral)
chr15_-_16946124 1.44 ENSDART00000154923
hip1
huntingtin interacting protein 1
chr12_-_17152139 1.43 ENSDART00000152478
stambpl1
STAM binding protein-like 1
chr19_-_27550768 1.42 ENSDART00000142313
si:dkeyp-46h3.8
si:dkeyp-46h3.8
chr15_+_29024895 1.41 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr18_-_3520358 1.41 ENSDART00000181412
capn5a
calpain 5a
chr13_-_24717618 1.40 ENSDART00000172156
erlin1
ER lipid raft associated 1
chr17_+_24318753 1.40 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr12_+_19408373 1.39 ENSDART00000114248
snx29
sorting nexin 29
chr7_+_71955486 1.38 ENSDART00000189349
CABZ01071171.1
Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA.
chr12_-_20616160 1.38 ENSDART00000105362
snx11
sorting nexin 11
chr5_-_54712159 1.38 ENSDART00000149207
ccnb1
cyclin B1
chr3_+_24062748 1.37 ENSDART00000188574
cbx1a
chromobox homolog 1a (HP1 beta homolog Drosophila)
chr11_-_25257045 1.37 ENSDART00000130477
snai1a
snail family zinc finger 1a
chr5_-_36597612 1.36 ENSDART00000031270
ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr13_+_39277178 1.36 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr1_-_55044256 1.36 ENSDART00000165505
ENSDART00000167536
ENSDART00000170001
vps54
vacuolar protein sorting 54 homolog (S. cerevisiae)
chr2_-_45663945 1.35 ENSDART00000075080
prpf38b
pre-mRNA processing factor 38B
chr2_+_3823813 1.35 ENSDART00000103596
ENSDART00000161880
ENSDART00000185408
npc1
Niemann-Pick disease, type C1
chr7_-_24112484 1.35 ENSDART00000111923
ajuba
ajuba LIM protein
chr17_-_30521043 1.33 ENSDART00000087111
itsn2b
intersectin 2b
chr15_-_1843831 1.33 ENSDART00000156718
ENSDART00000154175
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr10_+_15967341 1.32 ENSDART00000115130
ENSDART00000189687
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr5_+_44846280 1.31 ENSDART00000084370
kank1a
KN motif and ankyrin repeat domains 1a
chr12_-_33817114 1.31 ENSDART00000161265
twnk
twinkle mtDNA helicase
chr1_+_44173245 1.30 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr16_+_40340222 1.30 ENSDART00000190631
mettl6
methyltransferase like 6
chr5_-_54554583 1.30 ENSDART00000158865
ENSDART00000158069
ssna1
Sjogren syndrome nuclear autoantigen 1
chr12_-_44759246 1.30 ENSDART00000162888
dock1
dedicator of cytokinesis 1
chr7_-_51773166 1.29 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr5_-_15283509 1.29 ENSDART00000052712
gnb1l
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr9_+_2452672 1.29 ENSDART00000193993
chn1
chimerin 1
chr2_+_22409249 1.29 ENSDART00000182915
zgc:56628
zgc:56628
chr11_+_24313931 1.28 ENSDART00000017599
ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr21_-_32781612 1.28 ENSDART00000031028
cnot6a
CCR4-NOT transcription complex, subunit 6a
chr16_+_38940758 1.28 ENSDART00000102482
ENSDART00000136215
eny2
enhancer of yellow 2 homolog (Drosophila)
chr11_+_11303458 1.26 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr5_-_65662996 1.26 ENSDART00000147707
camsap1b
calmodulin regulated spectrin-associated protein 1b
chr8_-_13722682 1.26 ENSDART00000142052
si:dkey-258f14.2
si:dkey-258f14.2
chr17_+_21887823 1.26 ENSDART00000131929
ENSDART00000165192
plekha1a
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a
chr10_+_15967643 1.26 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr7_+_32695954 1.25 ENSDART00000184425
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr5_-_48664522 1.25 ENSDART00000083229
mblac2
metallo-beta-lactamase domain containing 2
chr9_+_32178374 1.24 ENSDART00000078576
coq10b
coenzyme Q10B
chr16_-_25368048 1.24 ENSDART00000132445
rbfa
ribosome binding factor A
chr25_+_7532811 1.24 ENSDART00000161593
ptdss2
phosphatidylserine synthase 2
chr6_-_41138854 1.24 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr9_-_41040492 1.23 ENSDART00000163164
adat3
adenosine deaminase, tRNA-specific 3
chr16_-_28658341 1.23 ENSDART00000148456
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr13_+_47710434 1.23 ENSDART00000188724
TMEM87B
transmembrane protein 87B
chr1_+_2301961 1.23 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_32337653 1.22 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
si:dkey-16p21.8
chr18_+_26428829 1.22 ENSDART00000190779
ENSDART00000193226
ENSDART00000110746
blm
Bloom syndrome, RecQ helicase-like
chr1_+_2321384 1.22 ENSDART00000157662
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr18_-_12295092 1.22 ENSDART00000033248
fam107b
family with sequence similarity 107, member B
chr21_+_13327527 1.22 ENSDART00000114294
snrpd3l
small nuclear ribonucleoprotein D3 polypeptide, like
chr16_+_39146696 1.21 ENSDART00000121756
ENSDART00000084381
sybu
syntabulin (syntaxin-interacting)
chr20_+_29565906 1.21 ENSDART00000062383
ywhaqa
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
chr8_+_23355484 1.21 ENSDART00000085361
ENSDART00000125729
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr17_+_17764979 1.20 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr15_+_1534644 1.20 ENSDART00000130413
smc4
structural maintenance of chromosomes 4
chr22_-_10158038 1.20 ENSDART00000047444
rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr20_+_14789305 1.20 ENSDART00000002463
tmed5
transmembrane p24 trafficking protein 5
chr10_+_15454745 1.19 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbin
erbb2 interacting protein
chr20_-_25643667 1.19 ENSDART00000137457
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr8_-_30395888 1.18 ENSDART00000144637
dock8
dedicator of cytokinesis 8
chr24_-_26622423 1.18 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr22_-_881725 1.17 ENSDART00000035514
cept1b
choline/ethanolamine phosphotransferase 1b
chr10_+_5234327 1.17 ENSDART00000133927
ENSDART00000063120
sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr24_-_36238054 1.17 ENSDART00000155725
tmem241
transmembrane protein 241
chr25_-_2723902 1.17 ENSDART00000143721
ENSDART00000175224
adpgk
ADP-dependent glucokinase
chr14_+_45028062 1.17 ENSDART00000184717
ENSDART00000185481
ATP8A1
ATPase phospholipid transporting 8A1
chr24_+_29912509 1.16 ENSDART00000168422
frrs1b
ferric-chelate reductase 1b
chr8_-_39822917 1.16 ENSDART00000067843
zgc:162025
zgc:162025
chr3_+_46764022 1.15 ENSDART00000023814
prkcsh
protein kinase C substrate 80K-H
chr18_+_15876385 1.15 ENSDART00000142527
eea1
early endosome antigen 1
chr12_+_30788912 1.15 ENSDART00000160422
aldh18a1
aldehyde dehydrogenase 18 family, member A1
chr16_+_7380463 1.15 ENSDART00000029727
ENSDART00000149086
atg5
ATG5 autophagy related 5 homolog (S. cerevisiae)
chr23_+_43718115 1.14 ENSDART00000149266
ENSDART00000149503
anapc10
anaphase promoting complex subunit 10
chr20_-_34670236 1.14 ENSDART00000033325
slc25a24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr15_-_26931541 1.14 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr21_+_3166519 1.14 ENSDART00000160585
hnrnpabb
heterogeneous nuclear ribonucleoprotein A/Bb
chr5_-_48070779 1.13 ENSDART00000078401
tmem161b
transmembrane protein 161B
chr21_-_22122312 1.13 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr14_+_16036139 1.12 ENSDART00000190733
prelid1a
PRELI domain containing 1a
chr15_+_25439106 1.12 ENSDART00000156252
aifm4
apoptosis-inducing factor, mitochondrion-associated, 4
chr12_-_17686404 1.12 ENSDART00000079065
ccz1
CCZ1 homolog, vacuolar protein trafficking and biogenesis associated
chr8_+_50190742 1.12 ENSDART00000099863
slc25a37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr22_+_2751887 1.11 ENSDART00000133652
si:dkey-20i20.11
si:dkey-20i20.11
chr15_-_23721618 1.11 ENSDART00000109318
zc3h4
zinc finger CCCH-type containing 4
chr2_-_21170517 1.10 ENSDART00000135417
bmi1b
bmi1 polycomb ring finger oncogene 1b
chr16_-_10223741 1.10 ENSDART00000188099
si:rp71-15i12.1
si:rp71-15i12.1
chr5_-_62940851 1.10 ENSDART00000137052
specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr9_-_30259295 1.09 ENSDART00000139106
si:dkey-100n23.5
si:dkey-100n23.5
chr24_-_33801668 1.09 ENSDART00000079202
abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr24_+_36840652 1.09 ENSDART00000088168
CABZ01055347.1

chr8_+_9699111 1.08 ENSDART00000111853
gripap1
GRIP1 associated protein 1
chr19_-_30447611 1.08 ENSDART00000073705
ENSDART00000048977
ENSDART00000191237
abcf1
ATP-binding cassette, sub-family F (GCN20), member 1
chr21_+_3166988 1.08 ENSDART00000168163
hnrnpabb
heterogeneous nuclear ribonucleoprotein A/Bb
chr9_-_34269066 1.08 ENSDART00000059955
ildr1b
immunoglobulin-like domain containing receptor 1b
chr16_-_42965192 1.08 ENSDART00000113714
mtx1a
metaxin 1a
chr20_-_48700370 1.08 ENSDART00000185195
ENSDART00000184898
pax1b
paired box 1b
chr10_+_8197827 1.07 ENSDART00000026244
mtrex
Mtr4 exosome RNA helicase
chr8_-_31416403 1.07 ENSDART00000098912
znf131
zinc finger protein 131
chr13_-_23067381 1.07 ENSDART00000078140
vps26a
vacuolar protein sorting 26 homolog A (S. pombe)
chr6_-_33685325 1.07 ENSDART00000181883
mast2
microtubule associated serine/threonine kinase 2
chr5_-_29531948 1.07 ENSDART00000098360
arrdc1a
arrestin domain containing 1a
chr16_+_40340523 1.06 ENSDART00000102571
mettl6
methyltransferase like 6
chr18_+_18000695 1.06 ENSDART00000146898
si:ch211-212o1.2
si:ch211-212o1.2
chr3_-_32873641 1.05 ENSDART00000075277
zgc:113090
zgc:113090
chr25_-_25142387 1.05 ENSDART00000031814
tsg101a
tumor susceptibility 101a
chr5_+_67835595 1.05 ENSDART00000159386
si:ch211-271b14.1
si:ch211-271b14.1
chr19_-_432083 1.04 ENSDART00000165371
dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr5_-_11809710 1.04 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
nf2a
neurofibromin 2a (merlin)
chr3_+_17933132 1.04 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr22_-_31517300 1.03 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr14_+_14841685 1.03 ENSDART00000158291
ENSDART00000162039
slbp
stem-loop binding protein
chr8_+_13364950 1.02 ENSDART00000159760
slc5a5
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr3_-_43650189 1.02 ENSDART00000161127
axin1
axin 1
chr8_+_35964482 1.02 ENSDART00000129357
ENSDART00000154953
glt1d1
glycosyltransferase 1 domain containing 1
chr23_+_39963599 1.02 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr3_-_36364903 1.02 ENSDART00000028883
gna13b
guanine nucleotide binding protein (G protein), alpha 13b
chr10_+_15608326 1.02 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr16_+_13883872 1.02 ENSDART00000101304
ENSDART00000136005
atg12
ATG12 autophagy related 12 homolog (S. cerevisiae)
chr16_-_41646164 1.02 ENSDART00000184257
atp2c1
ATPase secretory pathway Ca2+ transporting 1
chr1_+_6225493 1.01 ENSDART00000145378
fastkd2
FAST kinase domains 2
chr12_-_13650344 1.01 ENSDART00000124364
ENSDART00000124638
ENSDART00000171929
stat5b
signal transducer and activator of transcription 5b
chr8_-_28274552 1.01 ENSDART00000131580
rap1aa
RAP1A, member of RAS oncogene family a
chr17_-_10498347 1.01 ENSDART00000171324
mipol1
mirror-image polydactyly 1
chr19_+_40069524 1.00 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr5_+_9037650 1.00 ENSDART00000158226
si:ch211-155m12.1
si:ch211-155m12.1
chr13_+_22675802 1.00 ENSDART00000145538
ENSDART00000143312
zgc:193505
zgc:193505
chr4_-_1776352 0.99 ENSDART00000123089
dnajc2
DnaJ (Hsp40) homolog, subfamily C, member 2
chr5_-_39805874 0.99 ENSDART00000176202
ENSDART00000191683
rasgef1ba
RasGEF domain family, member 1Ba
chr3_+_26244353 0.99 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr16_+_35916371 0.99 ENSDART00000167208
sh3d21
SH3 domain containing 21

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa11b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.7 2.2 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 1.7 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.5 3.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.5 5.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.5 5.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 1.3 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 1.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.4 1.6 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.2 GO:0097065 anterior head development(GO:0097065)
0.4 1.9 GO:2000301 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.4 2.6 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.3 3.4 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.3 1.3 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.3 1.3 GO:0021557 oculomotor nerve development(GO:0021557)
0.3 1.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.3 1.2 GO:0060074 synapse maturation(GO:0060074)
0.3 1.5 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.3 2.0 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.3 0.8 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 1.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.3 1.4 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.3 1.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 1.3 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 1.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.3 1.0 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.3 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.2 1.2 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.2 1.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.2 0.7 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.9 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.2 0.7 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 2.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.2 4.0 GO:0035459 cargo loading into vesicle(GO:0035459)
0.2 1.1 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.2 3.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 1.5 GO:0015809 arginine transport(GO:0015809)
0.2 1.9 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 1.0 GO:0055071 manganese ion homeostasis(GO:0055071)
0.2 1.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.2 2.4 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 3.0 GO:0016075 rRNA catabolic process(GO:0016075)
0.2 0.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.8 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.2 0.5 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.2 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.2 0.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 1.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 0.5 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.2 0.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 1.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.2 1.8 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.2 2.4 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.2 0.6 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 0.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.2 3.2 GO:0006491 N-glycan processing(GO:0006491)
0.2 1.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.2 0.9 GO:0016572 histone phosphorylation(GO:0016572)
0.1 1.0 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) histone mRNA metabolic process(GO:0008334)
0.1 1.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.9 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 1.2 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.6 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 0.5 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.3 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 1.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.5 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 2.7 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.6 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 1.0 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.1 0.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.6 GO:0015729 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.7 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.3 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.6 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.4 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.5 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.1 0.8 GO:0035912 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.9 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.3 GO:0002631 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.5 GO:0097094 regulation of osteoblast proliferation(GO:0033688) craniofacial suture morphogenesis(GO:0097094)
0.1 0.8 GO:0044211 CTP salvage(GO:0044211)
0.1 0.4 GO:1905038 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 1.0 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.1 0.3 GO:0030238 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.1 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 1.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 0.7 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 2.8 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 1.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.2 GO:0051014 actin filament severing(GO:0051014)
0.1 1.0 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.5 GO:0048478 replication fork protection(GO:0048478)
0.1 1.9 GO:0022011 myelination in peripheral nervous system(GO:0022011)
0.1 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.4 GO:0009988 cell-cell recognition(GO:0009988)
0.1 1.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.4 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.2 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 1.3 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.7 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 1.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 1.1 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 0.4 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 1.2 GO:1901661 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.1 1.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 2.3 GO:0003094 glomerular filtration(GO:0003094)
0.1 1.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 1.3 GO:0009636 response to toxic substance(GO:0009636)
0.1 1.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.9 GO:0006415 translational termination(GO:0006415)
0.1 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.1 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 0.5 GO:0071174 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.1 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 1.2 GO:0006825 copper ion transport(GO:0006825)
0.1 0.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.2 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.1 0.3 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.4 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.1 0.2 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.1 0.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.1 0.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 2.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0034627 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.2 GO:0018377 N-terminal protein myristoylation(GO:0006499) N-terminal peptidyl-glycine N-myristoylation(GO:0018008) protein myristoylation(GO:0018377)
0.0 1.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.1 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.3 GO:1900027 regulation of ruffle assembly(GO:1900027) positive regulation of ruffle assembly(GO:1900029)
0.0 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 1.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.8 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.0 0.8 GO:0008354 germ cell migration(GO:0008354)
0.0 1.3 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.7 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.3 GO:0061641 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.5 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.8 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.2 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 1.3 GO:0001878 response to yeast(GO:0001878)
0.0 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 1.1 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.9 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 1.8 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 1.2 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0070169 positive regulation of bone mineralization(GO:0030501) positive regulation of ossification(GO:0045778) positive regulation of biomineral tissue development(GO:0070169)
0.0 0.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0090594 inflammatory response to wounding(GO:0090594)
0.0 0.6 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 2.3 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.5 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 1.6 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 5.3 GO:0007034 vacuolar transport(GO:0007034)
0.0 0.3 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 1.5 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 1.5 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.6 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 2.4 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 1.8 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.0 GO:0032640 tumor necrosis factor production(GO:0032640) positive regulation of interleukin-6 production(GO:0032755) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.0 0.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.3 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.4 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.8 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.7 GO:0046466 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.2 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 4.8 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.1 GO:0018210 peptidyl-threonine modification(GO:0018210)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.1 GO:2000725 regulation of cardiac muscle tissue development(GO:0055024) regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.0 0.1 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of hormone metabolic process(GO:0032350) histone H3-K4 demethylation(GO:0034720) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.2 GO:0031297 replication fork processing(GO:0031297)
0.0 0.5 GO:0034111 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 1.0 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.3 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.2 GO:0051642 centrosome localization(GO:0051642)
0.0 0.3 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0019859 thymine catabolic process(GO:0006210) uracil catabolic process(GO:0006212) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.9 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.1 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0032231 regulation of actin filament bundle assembly(GO:0032231)
0.0 0.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.3 GO:0006298 mismatch repair(GO:0006298)
0.0 1.9 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.3 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.4 GO:0031647 regulation of protein stability(GO:0031647)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0097189 apoptotic body(GO:0097189)
0.7 2.9 GO:0017177 glucosidase II complex(GO:0017177)
0.6 1.7 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.5 1.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.4 1.4 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 1.8 GO:0005784 Sec61 translocon complex(GO:0005784)
0.3 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.3 1.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 2.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.3 1.3 GO:0070390 transcription export complex 2(GO:0070390)
0.3 1.8 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 0.9 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.2 1.4 GO:0000938 GARP complex(GO:0000938)
0.2 0.6 GO:0031213 RSF complex(GO:0031213)
0.2 1.8 GO:0036449 microtubule minus-end(GO:0036449)
0.2 0.9 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 1.0 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.2 1.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 0.5 GO:0034457 Mpp10 complex(GO:0034457)
0.2 3.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 1.8 GO:0030904 retromer complex(GO:0030904)
0.1 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 3.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.2 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.4 GO:0030689 Noc complex(GO:0030689)
0.1 0.6 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.0 GO:0031526 brush border membrane(GO:0031526)
0.1 0.4 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.9 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.7 GO:0001650 fibrillar center(GO:0001650) multimeric ribonuclease P complex(GO:0030681)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 2.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.6 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 0.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 1.6 GO:0032039 integrator complex(GO:0032039)
0.1 1.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.8 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.4 GO:0000776 kinetochore(GO:0000776)
0.1 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 4.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0035101 FACT complex(GO:0035101)
0.1 2.3 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688) Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 2.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 10.0 GO:0005764 lysosome(GO:0005764)
0.0 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 2.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.5 GO:0043596 nuclear replication fork(GO:0043596)
0.0 2.1 GO:0005795 Golgi stack(GO:0005795)
0.0 1.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 2.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 3.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 1.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 6.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.7 5.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.7 2.8 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.4 2.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.4 1.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4 1.2 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.4 1.2 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.4 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.0 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.3 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.3 1.2 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.3 0.9 GO:0030623 U5 snRNA binding(GO:0030623)
0.3 2.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.3 1.3 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.2 1.2 GO:0016531 copper chaperone activity(GO:0016531)
0.2 1.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.2 1.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.2 1.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.2 0.6 GO:0000996 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.2 1.4 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.2 0.8 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.2 0.6 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.2 1.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 0.7 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.2 1.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.2 0.9 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.2 0.7 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 0.5 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 1.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.7 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.2 1.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 2.5 GO:2001069 glycogen binding(GO:2001069)
0.2 1.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.2 1.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.5 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 1.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 2.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 1.8 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 2.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.4 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 1.2 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.6 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 1.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.6 GO:0043531 ADP binding(GO:0043531)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.7 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 2.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 2.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 2.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 1.0 GO:0048038 quinone binding(GO:0048038)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 3.6 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 2.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.6 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0016972 thiol oxidase activity(GO:0016972)
0.1 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.4 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.8 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 7.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.2 GO:0005109 frizzled binding(GO:0005109)
0.1 0.8 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.0 0.8 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.7 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.7 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 1.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 1.0 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.8 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.9 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0030882 lipid antigen binding(GO:0030882)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 1.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 1.4 GO:0015370 solute:sodium symporter activity(GO:0015370)
0.0 0.7 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.4 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0004788 thiamine diphosphokinase activity(GO:0004788) thiamine binding(GO:0030975)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 2.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.9 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.9 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.4 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 1.1 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 1.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.0 GO:0015297 antiporter activity(GO:0015297)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.0 GO:0008168 methyltransferase activity(GO:0008168)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.0 PID FOXO PATHWAY FoxO family signaling
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.8 PID AURORA B PATHWAY Aurora B signaling
0.1 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.9 PID E2F PATHWAY E2F transcription factor network
0.1 3.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.8 PID ATM PATHWAY ATM pathway
0.1 0.8 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.1 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 3.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 1.2 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.5 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 2.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.2 5.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 3.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.2 1.8 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.2 1.1 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.2 2.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 1.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.8 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 2.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 2.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.6 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.8 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers