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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxa13a+hoxa13b

Z-value: 0.64

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Transcription factors associated with hoxa13a+hoxa13b

Gene Symbol Gene ID Gene Info
ENSDARG00000036254 homeobox A13b
ENSDARG00000100312 homeobox A13a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxa13bdr11_v1_chr16_+_20895904_208959040.599.6e-03Click!
hoxa13adr11_v1_chr19_+_19729506_197295060.484.5e-02Click!

Activity profile of hoxa13a+hoxa13b motif

Sorted Z-values of hoxa13a+hoxa13b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_39606108 2.08 ENSDART00000109464
G0/G1 switch 2
chr7_-_30367650 1.54 ENSDART00000075519
aldehyde dehydrogenase 1 family, member A2
chr14_+_80685 1.48 ENSDART00000188443
stromal antigen 3
chr6_+_13039951 1.30 ENSDART00000091700
ciliogenesis associated TTC17 interacting protein
chr19_-_10881486 1.17 ENSDART00000168852
ENSDART00000160438
proteasome 26S subunit, non-ATPase 4
proteasome 26S subunit, non-ATPase 4a
chr12_+_19356623 1.10 ENSDART00000078284
DNA meiotic recombinase 1
chr5_-_23200880 1.08 ENSDART00000051531
IQ motif containing D
chr20_+_2139436 1.07 ENSDART00000155311
l(3)mbt-like 3 (Drosophila)
chr17_+_21295132 1.06 ENSDART00000103845
enolase family member 4
chr13_-_37619159 0.99 ENSDART00000186348
zgc:152791
chr21_+_22845317 0.99 ENSDART00000065555
baculoviral IAP repeat containing 2
chr25_+_34641536 0.99 ENSDART00000167033

chr21_-_2299002 0.99 ENSDART00000168712
si:ch73-299h12.6
chr3_-_19200571 0.97 ENSDART00000131503
ENSDART00000012335
regulatory factor X, 1a (influences HLA class II expression)
chr10_+_26612321 0.96 ENSDART00000134322
four and a half LIM domains 1b
chr14_-_21123551 0.96 ENSDART00000171679
ENSDART00000165882
si:dkey-74k8.4
chr5_+_67971627 0.94 ENSDART00000144879
mitochondrial translational initiation factor 3
chr8_+_17933475 0.94 ENSDART00000100651
glutamate-rich 3
chr23_+_19813677 0.93 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr20_-_50049099 0.92 ENSDART00000123634
NADH:ubiquinone oxidoreductase subunit B1
chr16_+_4838808 0.92 ENSDART00000179363
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr6_+_7421898 0.91 ENSDART00000043946
coiled-coil domain containing 65
chr3_-_7656059 0.90 ENSDART00000170917
JunB proto-oncogene, AP-1 transcription factor subunit b
chr12_+_2870671 0.89 ENSDART00000165225
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b
chr21_-_37733287 0.88 ENSDART00000157826
membrane protein, palmitoylated 1
chr25_-_10503043 0.88 ENSDART00000155404
cytochrome c oxidase subunit 8b
chr22_-_547748 0.88 ENSDART00000037455
ENSDART00000140101
cyclin D3
chr21_+_45366229 0.87 ENSDART00000029946
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr4_-_5652030 0.86 ENSDART00000010903
radial spoke head 9 homolog
chr5_-_36948586 0.84 ENSDART00000193606
H3 histone, family 3C
chr19_+_17385561 0.84 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
ribosomal protein L15
chr23_+_42810055 0.82 ENSDART00000186647
myosin, light chain 9a, regulatory
chr7_+_12371061 0.82 ENSDART00000053860
stabilizer of axonemal microtubules 2
chr2_-_53896300 0.81 ENSDART00000161221
calcyphosine-like a
chr24_+_40860320 0.80 ENSDART00000161351
golgi reassembly stacking protein 1b
chr21_-_25756119 0.80 ENSDART00000002341
claudin c
chr6_-_2627488 0.79 ENSDART00000044089
ENSDART00000158333
ENSDART00000155109
hydroxypyruvate isomerase
chr3_+_16771797 0.79 ENSDART00000147418
leucine rich repeat containing 3Cb
chr13_+_37022601 0.78 ENSDART00000131800
ENSDART00000041300
estrogen receptor 2b
chr19_+_20778011 0.77 ENSDART00000024208
nuclear transport factor 2, like
chr6_-_19683406 0.77 ENSDART00000158041
cilia and flagella associated protein 52
chr3_+_13600714 0.77 ENSDART00000162124
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr11_-_1392468 0.77 ENSDART00000004423
isoleucyl-tRNA synthetase
chr4_-_64703 0.76 ENSDART00000167851

chr15_-_20933574 0.75 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
ubiquitin specific peptidase 2a
chr17_-_15382704 0.74 ENSDART00000005313
zgc:85722
chr16_-_54471235 0.74 ENSDART00000061572
cytochrome P450, family 11, subfamily C, polypeptide 1
chr2_+_49569017 0.72 ENSDART00000109471
semaphorin 4e
chr12_+_8074343 0.72 ENSDART00000124084
ciliary associated calcium binding coiled-coil 1
chr16_+_42830152 0.72 ENSDART00000159730
polymerase (RNA) III (DNA directed) polypeptide G like b
chr21_+_44557006 0.70 ENSDART00000170159
C-x(9)-C motif containing 4 homolog (S. cerevisiae)
chr6_+_43015916 0.70 ENSDART00000064888
T cell leukemia translocation altered
chr16_+_41668474 0.69 ENSDART00000141293
ENSDART00000102721
UBX domain protein 11
chr5_-_61970674 0.69 ENSDART00000143161
zinc finger protein 541
chr16_+_42829735 0.69 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr10_-_34889053 0.68 ENSDART00000136966
coiled-coil domain containing 169
chr8_+_37755099 0.68 ENSDART00000075708
ENSDART00000140966
glutamic-oxaloacetic transaminase 1 like 1
chr20_+_52546186 0.67 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr19_+_40177246 0.67 ENSDART00000049147
RNA binding motif protein 48
chr16_-_21785261 0.67 ENSDART00000078858
si:ch73-86n18.1
chr4_+_14926948 0.66 ENSDART00000019647
proteasome 26S subunit, ATPase 2
chr17_+_7513673 0.66 ENSDART00000156674
kelch-like family member 10b, tandem duplicate 1
chr15_+_25683069 0.65 ENSDART00000148190
hypermethylated in cancer 1
chr23_+_19182819 0.64 ENSDART00000131804
si:dkey-93l1.4
chr3_-_37759969 0.64 ENSDART00000151105
ENSDART00000151208
si:dkey-260c8.6
chr22_-_910926 0.64 ENSDART00000180075

chr20_-_40487208 0.64 ENSDART00000075070
ENSDART00000142029
heat shock transcription factor 2
chr20_+_34717403 0.64 ENSDART00000034252
prepronociceptin b
chr6_+_46431848 0.63 ENSDART00000181056
ENSDART00000144569
ENSDART00000064865
ENSDART00000133992
staufen double-stranded RNA binding protein 1
chr14_-_15171435 0.63 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr13_+_17694845 0.62 ENSDART00000079778
interferon-induced protein with tetratricopeptide repeats 8
chr7_+_59169081 0.62 ENSDART00000167980
oligosaccharyltransferase complex subunit
chr14_-_24391424 0.62 ENSDART00000113376
ENSDART00000126894
family with sequence similarity 13, member B
chr6_+_27514465 0.61 ENSDART00000128985
ENSDART00000079397
receptor-like tyrosine kinase
chr15_-_34567370 0.60 ENSDART00000099793
sclerostin domain containing 1a
chr17_-_26610814 0.60 ENSDART00000133402
ENSDART00000016608
mitochondrial ribosomal protein L57
chr20_-_22798794 0.60 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr11_-_12364122 0.59 ENSDART00000170129
zgc:174353
chr12_-_31457301 0.59 ENSDART00000043887
ENSDART00000148603
acyl-CoA synthetase long chain family member 5
chr10_+_42678520 0.59 ENSDART00000182496
Rho-related BTB domain containing 2b
chr12_+_26471712 0.58 ENSDART00000162115
nudE neurodevelopment protein 1-like 1a
chr2_-_5728843 0.58 ENSDART00000014020
somatostatin 2
chr22_+_18188045 0.58 ENSDART00000140106
myocyte enhancer factor 2b
chr24_+_24923166 0.58 ENSDART00000065288
phosphate cytidylyltransferase 1, choline, beta a
chr5_-_1203455 0.57 ENSDART00000172177
surfeit gene 4
chr6_-_43233700 0.57 ENSDART00000113706
tRNA nucleotidyl transferase, CCA-adding, 1
chr19_+_7810028 0.57 ENSDART00000081592
ENSDART00000140719
aquaporin 10b
chr3_-_55147731 0.57 ENSDART00000155871
ENSDART00000109016
ENSDART00000122904
hemoglobin alpha embryonic-3
chr16_-_45917322 0.57 ENSDART00000060822
antifreeze protein type IV
chr20_+_33739059 0.57 ENSDART00000140361
peptidylprolyl isomerase (cyclophilin)-like 6
chr3_-_53091946 0.56 ENSDART00000187297
lysophosphatidic acid receptor 2a
chr17_-_12407106 0.55 ENSDART00000183540
ankyrin repeat and EF-hand domain containing 1b
chr22_+_15624371 0.55 ENSDART00000124868
lipoprotein lipase
chr11_+_7580079 0.55 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr22_+_18187857 0.54 ENSDART00000166300
myocyte enhancer factor 2b
chr10_+_2899108 0.54 ENSDART00000147031
endoplasmic reticulum aminopeptidase 1a
chr7_-_26457208 0.54 ENSDART00000173519
zgc:172079
chr16_-_27543024 0.54 ENSDART00000147737
ENSDART00000078283
testis expressed 10
chr13_+_25380432 0.54 ENSDART00000038524
glutathione S-transferase omega 1
chr20_-_52338782 0.53 ENSDART00000109735
ENSDART00000132941
si:ch1073-287p18.1
chr17_-_10309766 0.53 ENSDART00000160994
tetratricopeptide repeat domain 6
chr2_+_14992879 0.53 ENSDART00000137546
Pim proto-oncogene, serine/threonine kinase, related 55
chr19_+_636886 0.53 ENSDART00000149192
telomerase reverse transcriptase
chr19_-_1948236 0.53 ENSDART00000163344
zinc and ring finger 2a
chr8_+_23809843 0.52 ENSDART00000099724
si:ch211-163l21.10
chr5_+_58687541 0.52 ENSDART00000083015
ENSDART00000181902
coiled-coil domain containing 84
chr2_-_24907741 0.52 ENSDART00000155013
si:dkey-149i17.11
chr4_-_149334 0.52 ENSDART00000163280
TANK-binding kinase 1
chr13_+_30804367 0.51 ENSDART00000053946
chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
chr17_-_17764801 0.51 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr21_-_43079161 0.51 ENSDART00000144151
janus kinase and microtubule interacting protein 2
chr13_+_24584401 0.50 ENSDART00000057599
fucose mutarotase
chr24_+_37903448 0.50 ENSDART00000155476
coiled-coil domain containing 78
chr22_+_24715282 0.50 ENSDART00000088027
ENSDART00000189054
ENSDART00000140430
synovial sarcoma, X breakpoint 2 interacting protein b
chr20_+_25586099 0.50 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr17_-_31695217 0.49 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr13_+_844150 0.49 ENSDART00000058260
glutathione S-transferase, alpha tandem duplicate 1
chr7_+_23515966 0.49 ENSDART00000186893
ENSDART00000186189
zgc:109889
chr13_+_45980163 0.49 ENSDART00000074547
ENSDART00000005195
BSD domain containing 1
chr6_-_49526510 0.49 ENSDART00000128025
ribosomal protein S26, like
chr6_-_17206028 0.48 ENSDART00000155756
Pim proto-oncogene, serine/threonine kinase, related 3
chr6_-_28943056 0.48 ENSDART00000065138
TBC1 domain family, member 23
chr19_-_32600823 0.48 ENSDART00000134149
ENSDART00000187858
zgc:91944
chr24_-_21674950 0.48 ENSDART00000123216
ENSDART00000046211
ligand of numb-protein X 2a
chr11_-_25539323 0.48 ENSDART00000155785
si:dkey-245f22.3
chr22_+_2937485 0.48 ENSDART00000082222
ENSDART00000135507
ENSDART00000143258
centrosomal protein 19
chr16_-_52821023 0.48 ENSDART00000074718
spire-type actin nucleation factor 1b
chr22_+_2409175 0.48 ENSDART00000141776
zgc:113220
chr14_+_15495088 0.47 ENSDART00000165765
ENSDART00000188577
si:dkey-203a12.6
chr5_+_23597144 0.47 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
K(lysine) acetyltransferase 5b
chr9_+_18716485 0.47 ENSDART00000135125
stress-associated endoplasmic reticulum protein family member 2
chr21_-_27195256 0.47 ENSDART00000133152
ENSDART00000065401
zgc:110782
chr21_+_4702773 0.47 ENSDART00000147404
si:dkey-102g19.3
chr2_-_30135446 0.47 ENSDART00000141906
transient receptor potential cation channel, subfamily A, member 1a
chr22_+_1911269 0.46 ENSDART00000164158
ENSDART00000168205
zinc finger protein 1156
chr21_+_22828500 0.46 ENSDART00000151109
si:rp71-1p14.7
chr6_-_8295657 0.46 ENSDART00000185135
solute carrier family 44 (choline transporter), member 2
chr5_-_26181863 0.46 ENSDART00000098500
coiled-coil domain containing 125
chr16_-_35585374 0.46 ENSDART00000180208
Scm polycomb group protein homolog 1
chr4_-_72573359 0.46 ENSDART00000130342
si:cabz01054396.2
chr22_-_2937503 0.45 ENSDART00000092991
ENSDART00000131110
phosphatidylinositol glycan anchor biosynthesis, class X
chr2_+_24352497 0.45 ENSDART00000134909
Pim proto-oncogene, serine/threonine kinase, related 68
chr25_-_16146851 0.45 ENSDART00000104043
dickkopf WNT signaling pathway inhibitor 3b
chr2_-_27975530 0.45 ENSDART00000020367
zgc:56556
chr1_+_50538839 0.45 ENSDART00000020412
polycystic kidney disease 2
chr25_-_8916913 0.45 ENSDART00000104629
ENSDART00000131748
furin (paired basic amino acid cleaving enzyme) b
chr24_+_21621654 0.45 ENSDART00000002595
ribosomal protein L21
chr10_+_42374770 0.45 ENSDART00000020000
zgc:86599
chr8_+_14381272 0.44 ENSDART00000057642
acyl-CoA binding domain containing 6
chr20_-_14012859 0.43 ENSDART00000152429
si:ch211-22i13.2
chr16_+_30575901 0.43 ENSDART00000077231
melanocortin 2 receptor
chr14_-_25042184 0.43 ENSDART00000131027
si:rp71-1d10.5
chr21_-_29364166 0.43 ENSDART00000188602

chr11_+_25539698 0.43 ENSDART00000035602
CXXC finger protein 1b
chr2_-_16159203 0.42 ENSDART00000153480
vav 3 guanine nucleotide exchange factor b
chr8_+_53051701 0.42 ENSDART00000131514
NAD kinase a
chr9_-_42696408 0.42 ENSDART00000144744
collagen, type V, alpha 2a
chr8_-_44299247 0.41 ENSDART00000144497
piwi-like RNA-mediated gene silencing 1
chr5_+_54555567 0.41 ENSDART00000171159
anaphase promoting complex subunit 2
chr9_-_48214216 0.41 ENSDART00000012938
phosphoglycerate dehydrogenase
chr2_-_24962820 0.41 ENSDART00000182767
helicase-like transcription factor
chr3_-_60316118 0.41 ENSDART00000171458
si:ch211-214b16.2
chr21_-_22827548 0.41 ENSDART00000079161
angiopoietin-like 5
chr24_+_23202545 0.41 ENSDART00000143862
peroxisomal biogenesis factor 2
chr21_+_11503212 0.41 ENSDART00000146701
si:dkey-184p9.7
chr4_-_18850799 0.41 ENSDART00000151844
malonyl CoA:ACP acyltransferase (mitochondrial)
chr10_+_18952271 0.41 ENSDART00000146517
dihydropyrimidinase-like 2b
chr13_-_37620091 0.41 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
chr5_+_43807003 0.41 ENSDART00000097625
zgc:158640
chr23_-_35694171 0.40 ENSDART00000077539
tubulin, alpha 1c
chr12_-_36521767 0.40 ENSDART00000110290
unc-13 homolog D (C. elegans)
chr21_+_13150937 0.40 ENSDART00000102251
spectrin alpha, non-erythrocytic 1
chr7_+_24494299 0.40 ENSDART00000087568
negative elongation factor complex member A
chr10_-_5016997 0.40 ENSDART00000101414
heterogeneous nuclear ribonucleoprotein D
chr16_+_21242491 0.40 ENSDART00000145886
oxysterol binding protein-like 3b
chr17_-_49280308 0.40 ENSDART00000059658
ENSDART00000169207
transcription factor B1, mitochondrial
chr24_-_9960290 0.40 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr23_+_7379728 0.40 ENSDART00000012194
GATA binding protein 5
chr5_-_9073433 0.39 ENSDART00000099891
ATP synthase membrane subunit eb
chr19_+_7835025 0.39 ENSDART00000026276
CDC28 protein kinase regulatory subunit 1B
chr1_-_35924495 0.39 ENSDART00000184424
SMAD family member 1
chr2_-_30182353 0.39 ENSDART00000019149
ribosomal protein L7
chr3_+_22059066 0.39 ENSDART00000155739
KAT8 regulatory NSL complex subunit 1b
chr14_-_24761132 0.39 ENSDART00000146299
slit homolog 3 (Drosophila)
chr9_+_41080029 0.39 ENSDART00000141179
ENSDART00000019289
zgc:136439
chr7_-_24364536 0.39 ENSDART00000064789
thioredoxin
chr11_-_3343463 0.39 ENSDART00000066177
tubulin, alpha 2
chr2_+_26682913 0.38 ENSDART00000010683
ENSDART00000131411
ENSDART00000137933
inositol monophosphatase 1
chr21_-_21781158 0.38 ENSDART00000113734
chordin-like 2
chr2_+_19578446 0.38 ENSDART00000164758
Pim proto-oncogene, serine/threonine kinase, related 50
chr7_+_49664174 0.38 ENSDART00000137059
ENSDART00000131210
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr22_-_35330532 0.38 ENSDART00000172654

chr1_-_13989643 0.38 ENSDART00000191046
E74-like factor 2b (ets domain transcription factor)
chr24_-_12689571 0.38 ENSDART00000015517
programmed cell death 6
chr22_+_14051245 0.38 ENSDART00000043711
ENSDART00000164259
aldehyde oxidase 6
chr6_+_49551614 0.38 ENSDART00000022581
RAB22A, member RAS oncogene family
chr3_-_23596809 0.38 ENSDART00000156897
ubiquitin-conjugating enzyme E2Z
chr13_+_13668991 0.38 ENSDART00000148266
Pim proto-oncogene, serine/threonine kinase, related 48
chr19_+_9097013 0.37 ENSDART00000139781
si:ch211-81a5.5
chr25_-_35360096 0.37 ENSDART00000154053
ENSDART00000171917
si:ch73-147o17.1

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxa13a+hoxa13b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 0.9 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 1.1 GO:0042148 strand invasion(GO:0042148)
0.2 1.0 GO:0060546 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.2 0.7 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.2 0.9 GO:0032790 ribosome disassembly(GO:0032790)
0.2 0.6 GO:2000193 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.2 0.5 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.2 0.7 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.7 GO:0006531 aspartate metabolic process(GO:0006531)
0.2 0.5 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.7 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.1 0.7 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:0050955 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.1 1.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.4 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.1 0.4 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.5 GO:0015871 choline transport(GO:0015871)
0.1 0.9 GO:0003352 regulation of cilium movement(GO:0003352)
0.1 0.8 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.7 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.3 GO:0036363 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 1.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.5 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.3 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.2 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.2 GO:0065001 specification of axis polarity(GO:0065001)
0.1 0.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 1.2 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.8 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.5 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.2 GO:1903392 epicardial cell to mesenchymal cell transition(GO:0003347) negative regulation of adherens junction organization(GO:1903392)
0.1 0.6 GO:0006833 water transport(GO:0006833)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.4 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.6 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.3 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 1.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 0.2 GO:1902746 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 0.5 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.9 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.2 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.1 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.3 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.1 0.2 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.2 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.1 0.2 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.2 GO:0048855 glossopharyngeal nerve development(GO:0021563) adenohypophysis morphogenesis(GO:0048855)
0.0 0.2 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.3 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.5 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.4 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.8 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.2 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.7 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.3 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.1 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.4 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0070861 regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.0 GO:0051793 medium-chain fatty acid metabolic process(GO:0051791) medium-chain fatty acid catabolic process(GO:0051793)
0.0 0.1 GO:0006589 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.0 0.3 GO:0071679 commissural neuron axon guidance(GO:0071679)
0.0 0.4 GO:0035108 limb morphogenesis(GO:0035108)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.6 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.1 GO:0010934 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0046323 glucose import(GO:0046323)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.6 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.9 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.2 GO:0010890 regulation of sequestering of triglyceride(GO:0010889) positive regulation of sequestering of triglyceride(GO:0010890) sequestering of triglyceride(GO:0030730)
0.0 0.2 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.7 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 5.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.0 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.4 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:0071696 ectodermal placode development(GO:0071696)
0.0 0.2 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.0 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 0.3 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.9 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.4 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:1901827 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.8 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0001534 radial spoke(GO:0001534)
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.2 0.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.8 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.4 GO:0030897 HOPS complex(GO:0030897)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.9 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0032021 NELF complex(GO:0032021)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 1.0 GO:0008278 cohesin complex(GO:0008278)
0.0 0.5 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 1.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.1 GO:0031514 motile cilium(GO:0031514)
0.0 0.6 GO:0043679 axon terminus(GO:0043679)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0000150 recombinase activity(GO:0000150)
0.2 0.7 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2 0.5 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 0.5 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.2 0.5 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 0.7 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 0.7 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 0.5 GO:0042806 fucose binding(GO:0042806)
0.1 1.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0034246 core DNA-dependent RNA polymerase binding promoter specificity activity(GO:0000996) mitochondrial RNA polymerase binding promoter specificity activity(GO:0034246)
0.1 0.8 GO:1903924 estradiol binding(GO:1903924)
0.1 0.4 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.5 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.3 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:0001729 ceramide kinase activity(GO:0001729) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.1 0.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.9 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.2 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.0 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.6 GO:0036122 BMP binding(GO:0036122)
0.1 0.2 GO:0043185 vascular endothelial growth factor receptor 3 binding(GO:0043185)
0.1 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.3 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.6 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.6 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.6 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.7 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.9 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0051379 epinephrine binding(GO:0051379)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0005111 type 1 fibroblast growth factor receptor binding(GO:0005105) type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0043295 glutathione binding(GO:0043295)
0.0 0.0 GO:0031704 apelin receptor binding(GO:0031704)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:1990238 double-stranded DNA endodeoxyribonuclease activity(GO:1990238)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.0 GO:0050251 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 2.8 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.7 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 1.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones