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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxb8a+hoxb8b

Z-value: 0.74

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Transcription factors associated with hoxb8a+hoxb8b

Gene Symbol Gene ID Gene Info
hoxb8b
ENSDARG00000054025 homeobox B8b
hoxb8a
ENSDARG00000056027 homeobox B8a
hoxb8b
ENSDARG00000111056 homeobox B8b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxb8bdr11_v1_chr12_+_27117609_271176090.068.2e-01Click!
hoxb8adr11_v1_chr3_+_23687909_236879090.048.9e-01Click!

Activity profile of hoxb8a+hoxb8b motif

Sorted Z-values of hoxb8a+hoxb8b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_4461104 2.19 ENSDART00000023090
ENSDART00000140770
slc12a10.1
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr1_+_16144615 1.69 ENSDART00000054707
tusc3
tumor suppressor candidate 3
chr17_-_2595736 1.51 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2573021 1.49 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr23_+_12545114 1.27 ENSDART00000105283
ENSDART00000166990
si:zfos-452g4.1
si:zfos-452g4.1
chr11_+_13528437 1.03 ENSDART00000011362
arrdc2
arrestin domain containing 2
chr11_+_3959495 0.92 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr21_-_31241254 0.91 ENSDART00000065365
tpst1l
tyrosylprotein sulfotransferase 1, like
chr24_-_7826489 0.86 ENSDART00000112777
si:dkey-197c15.6
si:dkey-197c15.6
chr16_-_26855936 0.84 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr3_+_26813058 0.80 ENSDART00000055537
socs1a
suppressor of cytokine signaling 1a
chr7_+_12927944 0.78 ENSDART00000027329
fth1a
ferritin, heavy polypeptide 1a
chr2_-_10821053 0.75 ENSDART00000056034
rpap2
RNA polymerase II associated protein 2
chr17_-_2578026 0.71 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr8_-_49495584 0.68 ENSDART00000141691
opn7d
opsin 7, group member d
chr17_-_8570257 0.68 ENSDART00000154713
ENSDART00000121488
fzd3b
frizzled class receptor 3b
chr22_+_35089031 0.65 ENSDART00000076040
srfa
serum response factor a
chr18_-_26715156 0.64 ENSDART00000142043
malt3
MALT paracaspase 3
chr9_+_50000504 0.64 ENSDART00000164409
ENSDART00000165451
ENSDART00000166509
slc38a11
solute carrier family 38, member 11
chr17_-_38778826 0.64 ENSDART00000168182
ENSDART00000124041
ENSDART00000136921
dglucy
D-glutamate cyclase
chr19_+_12444943 0.62 ENSDART00000135706
ldlrad4a
low density lipoprotein receptor class A domain containing 4a
chr5_-_25733745 0.60 ENSDART00000051566
zgc:101016
zgc:101016
chr16_+_10776688 0.60 ENSDART00000161969
ENSDART00000172657
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr3_-_34717882 0.58 ENSDART00000151127
thraa
thyroid hormone receptor alpha a
chr7_+_52154215 0.57 ENSDART00000098712
TMEM208
zgc:77041
chr20_+_54274431 0.57 ENSDART00000099338
actr10
ARP10 actin related protein 10 homolog
chr9_-_9415000 0.56 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr3_+_23752150 0.56 ENSDART00000146636
hoxb2a
homeobox B2a
chr13_-_36621926 0.56 ENSDART00000057155
cdkn3
cyclin-dependent kinase inhibitor 3
chr13_+_8604710 0.53 ENSDART00000091097
socs5b
suppressor of cytokine signaling 5b
chr15_-_34567370 0.53 ENSDART00000099793
sostdc1a
sclerostin domain containing 1a
chr24_+_38301080 0.50 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr20_-_22778394 0.50 ENSDART00000152645
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr3_+_33300522 0.49 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr1_-_9277986 0.49 ENSDART00000146065
ENSDART00000114876
ENSDART00000132812
ubn1
ubinuclein 1
chr9_+_42066030 0.46 ENSDART00000185311
ENSDART00000015267
pcbp3
poly(rC) binding protein 3
chr15_+_32405959 0.46 ENSDART00000177269
si:ch211-162k9.6
si:ch211-162k9.6
chr9_-_43644261 0.46 ENSDART00000023684
cwc22
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr5_-_34185115 0.45 ENSDART00000192771
fibcd1
fibrinogen C domain containing 1
chr18_+_783936 0.44 ENSDART00000193357
rpp25b
ribonuclease P and MRP subunit p25, b
chr11_-_3959477 0.42 ENSDART00000045971
pbrm1
polybromo 1
chr10_-_39011514 0.42 ENSDART00000075123
pcp4a
Purkinje cell protein 4a
chr24_+_34113424 0.42 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr6_-_53281518 0.40 ENSDART00000157621
rbm5
RNA binding motif protein 5
chr1_-_19402802 0.39 ENSDART00000135552
rbm47
RNA binding motif protein 47
chr5_-_825920 0.39 ENSDART00000126982
zgc:158463
zgc:158463
chr4_-_9909371 0.39 ENSDART00000102656
si:dkey-22l11.6
si:dkey-22l11.6
chr19_+_28256076 0.38 ENSDART00000133354
irx4b
iroquois homeobox 4b
chr10_+_43039947 0.37 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr11_-_3959889 0.37 ENSDART00000159683
pbrm1
polybromo 1
chr6_+_50451337 0.35 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr24_+_26328787 0.35 ENSDART00000003884
mynn
myoneurin
chr24_+_26329018 0.34 ENSDART00000145752
mynn
myoneurin
chr19_+_5480327 0.34 ENSDART00000148794
jupb
junction plakoglobin b
chr19_-_3876877 0.33 ENSDART00000163711
thrap3b
thyroid hormone receptor associated protein 3b
chr7_-_35126374 0.32 ENSDART00000141211
hsd11b2
hydroxysteroid (11-beta) dehydrogenase 2
chr7_-_46777876 0.32 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr3_+_59784632 0.32 ENSDART00000084729
pecam1
platelet/endothelial cell adhesion molecule 1
chr24_+_5789790 0.31 ENSDART00000189600
BX470065.1

chr24_-_6898302 0.31 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr2_+_7818368 0.30 ENSDART00000007068
kcnmb2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr18_-_26715655 0.30 ENSDART00000181497
malt3
MALT paracaspase 3
chr12_+_17201522 0.30 ENSDART00000014536
ENSDART00000152452
rnls
renalase, FAD-dependent amine oxidase
chr2_+_3809226 0.30 ENSDART00000147261
egfra
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr7_+_21272833 0.30 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr3_-_13599482 0.29 ENSDART00000166639
tufm
Tu translation elongation factor, mitochondrial
chr12_-_28848015 0.29 ENSDART00000153200
si:ch211-194k22.8
si:ch211-194k22.8
chr1_-_43862638 0.29 ENSDART00000145044
tacr3a
tachykinin receptor 3a
chr24_+_5789582 0.29 ENSDART00000141504
BX470065.1

chr10_-_45210184 0.29 ENSDART00000167128
pargl
poly (ADP-ribose) glycohydrolase, like
chr6_-_23931442 0.29 ENSDART00000160547
sec16b
SEC16 homolog B, endoplasmic reticulum export factor
chr2_-_24962820 0.28 ENSDART00000182767
hltf
helicase-like transcription factor
chr9_-_20372977 0.27 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr15_-_15968883 0.27 ENSDART00000166583
ENSDART00000154042
synrg
synergin, gamma
chr14_-_6666854 0.25 ENSDART00000133031
si:dkeyp-44a8.4
si:dkeyp-44a8.4
chr1_-_26071535 0.25 ENSDART00000185187
pdcd4a
programmed cell death 4a
chr7_+_13382852 0.25 ENSDART00000166318
dagla
diacylglycerol lipase, alpha
chr10_+_40321067 0.25 ENSDART00000109816
gltpb
glycolipid transfer protein b
chr11_+_36243774 0.24 ENSDART00000023323
zgc:172270
zgc:172270
chr21_-_23308286 0.24 ENSDART00000184419
zbtb16a
zinc finger and BTB domain containing 16a
chr4_-_5366566 0.22 ENSDART00000150788
si:dkey-14d8.1
si:dkey-14d8.1
chr18_-_14836862 0.22 ENSDART00000124843
mtss1la
metastasis suppressor 1-like a
chr15_+_8767650 0.22 ENSDART00000033871
ap2s1
adaptor-related protein complex 2, sigma 1 subunit
chr5_+_19261391 0.21 ENSDART00000089173
atp8b5a
ATPase phospholipid transporting 8B5a
chr4_+_13810811 0.21 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr14_+_5383060 0.21 ENSDART00000187825
lbx2
ladybird homeobox 2
chr10_-_27741793 0.21 ENSDART00000129369
ENSDART00000192440
ENSDART00000189808
ENSDART00000138149
auts2a
si:dkey-33o22.1
autism susceptibility candidate 2a
si:dkey-33o22.1
chr5_+_19261687 0.20 ENSDART00000139401
atp8b5a
ATPase phospholipid transporting 8B5a
chr16_+_17389116 0.19 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr16_-_54498109 0.19 ENSDART00000083713
clk2b
CDC-like kinase 2b
chr8_+_20503842 0.18 ENSDART00000100328
csnk1g2b
casein kinase 1, gamma 2b
chr2_+_47623202 0.17 ENSDART00000154465
si:ch211-165b10.3
si:ch211-165b10.3
chr12_+_39685485 0.17 ENSDART00000163403
LO017650.1

chr4_+_7391110 0.17 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr24_+_25259154 0.16 ENSDART00000171125
gabrr3b
gamma-aminobutyric acid (GABA) A receptor, rho 3b
chr21_-_40348790 0.16 ENSDART00000178123
CR847523.1

chr11_-_2838699 0.15 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr8_+_18588551 0.15 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr12_-_38548299 0.15 ENSDART00000153374
si:dkey-1f1.3
si:dkey-1f1.3
chr13_+_22316746 0.15 ENSDART00000188968
usp54a
ubiquitin specific peptidase 54a
chr25_+_15647750 0.15 ENSDART00000137375
spon1b
spondin 1b
chr4_-_55728559 0.14 ENSDART00000186201
CT583728.14

chr8_+_21437908 0.14 ENSDART00000142758
si:dkey-163f12.10
si:dkey-163f12.10
chr21_+_40092301 0.14 ENSDART00000145150
serpinf2a
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2a
chr15_+_28202170 0.14 ENSDART00000077736
vtna
vitronectin a
chr25_+_15647993 0.14 ENSDART00000186578
ENSDART00000031828
spon1b
spondin 1b
chr12_-_11457625 0.14 ENSDART00000012318
htra1b
HtrA serine peptidase 1b
chr15_-_30450898 0.14 ENSDART00000156584
msi2b
musashi RNA-binding protein 2b
chr7_+_31879649 0.13 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr2_+_2223837 0.13 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr24_+_13735616 0.13 ENSDART00000184267
msc
musculin (activated B-cell factor-1)
chr9_-_15789526 0.13 ENSDART00000141318
si:dkey-103d23.3
si:dkey-103d23.3
chr6_-_32087108 0.13 ENSDART00000150934
ENSDART00000130627
alg6
asparagine-linked glycosylation 6 (alpha-1,3,-glucosyltransferase)
chr17_+_39242437 0.13 ENSDART00000156138
ENSDART00000128863
zgc:174356
zgc:174356
chr20_-_19590378 0.13 ENSDART00000152588
baalcb
brain and acute leukemia, cytoplasmic b
chr19_-_3123963 0.13 ENSDART00000122816
si:ch211-80h18.1
si:ch211-80h18.1
chr1_+_51191049 0.13 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
btbd3a
BTB (POZ) domain containing 3a
chr13_-_5569562 0.12 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr11_+_6819050 0.12 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr18_-_38088099 0.12 ENSDART00000146120
luzp2
leucine zipper protein 2
chr24_-_40009446 0.12 ENSDART00000087422
aoc1
amine oxidase, copper containing 1
chr14_+_22297257 0.12 ENSDART00000113676
atp10b
ATPase phospholipid transporting 10B
chr24_+_5840258 0.11 ENSDART00000087034
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr13_-_5568928 0.11 ENSDART00000192679
meis1b
Meis homeobox 1 b
chr13_+_36622100 0.11 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr25_-_16157776 0.11 ENSDART00000138453
si:dkey-80c24.5
si:dkey-80c24.5
chr21_-_22812417 0.11 ENSDART00000079151
ENSDART00000112175
trpc6a
transient receptor potential cation channel, subfamily C, member 6a
chr23_+_21479958 0.11 ENSDART00000188302
ENSDART00000144320
si:dkey-1c11.1
si:dkey-1c11.1
chr12_-_26406323 0.10 ENSDART00000131896
myoz1b
myozenin 1b
chr13_-_8776474 0.10 ENSDART00000122371
STPG4
si:ch211-93n23.7
chr1_+_23784905 0.10 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr7_+_27976448 0.10 ENSDART00000181026
tub
tubby bipartite transcription factor
chr2_-_10188598 0.10 ENSDART00000189122
dmbx1a
diencephalon/mesencephalon homeobox 1a
chr22_+_18389271 0.10 ENSDART00000088270
yjefn3
YjeF N-terminal domain containing 3
chr11_+_23265157 0.10 ENSDART00000110152
csf1a
colony stimulating factor 1a (macrophage)
chr24_-_26328721 0.09 ENSDART00000125468
apodb
apolipoprotein Db
chr15_+_28116129 0.09 ENSDART00000185157
unc119a
unc-119 homolog a (C. elegans)
chr7_-_31938938 0.09 ENSDART00000132353
bdnf
brain-derived neurotrophic factor
chr21_+_5192016 0.09 ENSDART00000139288
si:dkey-121h17.7
si:dkey-121h17.7
chr12_-_3756405 0.09 ENSDART00000150839
fam57bb
family with sequence similarity 57, member Bb
chr7_+_31879986 0.09 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr6_+_14949950 0.09 ENSDART00000149202
ENSDART00000149949
pou3f3b
POU class 3 homeobox 3b
chr8_-_14484599 0.08 ENSDART00000057644
lhx4
LIM homeobox 4
chr1_-_8980665 0.08 ENSDART00000148182
si:ch73-191k20.3
si:ch73-191k20.3
chr3_-_33574576 0.08 ENSDART00000184881
CR847537.1

chr11_+_43419809 0.08 ENSDART00000172982
slc29a1b
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr13_-_30027730 0.08 ENSDART00000044009
scdb
stearoyl-CoA desaturase b
chr15_+_29727799 0.08 ENSDART00000182006
zgc:153372
zgc:153372
chr17_-_30666037 0.08 ENSDART00000156509
alkal2b
ALK and LTK ligand 2b
chr14_+_46274611 0.08 ENSDART00000134363
cabp2b
calcium binding protein 2b
chr4_-_77331797 0.08 ENSDART00000162325
slco1f3
solute carrier organic anion transporter family, member 1F3
chr3_-_29508959 0.08 ENSDART00000055408
cyth4a
cytohesin 4a
chr7_+_42460302 0.07 ENSDART00000004120
adamts18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr15_-_5467477 0.07 ENSDART00000123839
arrb1
arrestin, beta 1
chr4_-_9891874 0.07 ENSDART00000067193
adm2a
adrenomedullin 2a
chr6_+_52804267 0.07 ENSDART00000065681
matn4
matrilin 4
chr20_-_8443425 0.07 ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr5_-_24869213 0.07 ENSDART00000112287
ENSDART00000144635
gas2l1
growth arrest-specific 2 like 1
chr5_+_9382301 0.07 ENSDART00000124017
ugt2a7
UDP glucuronosyltransferase 2 family, polypeptide A7
chr20_-_29420713 0.07 ENSDART00000147464
ryr3
ryanodine receptor 3
chr20_-_43663494 0.06 ENSDART00000144564
BX470188.1

chr14_+_25465346 0.06 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr7_-_69983948 0.06 ENSDART00000185827
KCNIP4
potassium voltage-gated channel interacting protein 4
chr1_-_21901589 0.06 ENSDART00000140553
frmpd1a
FERM and PDZ domain containing 1a
chr21_+_22423286 0.06 ENSDART00000133190
capslb
calcyphosine-like b
chr14_+_4796168 0.06 ENSDART00000041468
ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr20_-_32188897 0.06 ENSDART00000133887
si:ch211-51a19.5
si:ch211-51a19.5
chr2_-_54039293 0.06 ENSDART00000166013
abhd8a
abhydrolase domain containing 8a
chr13_+_30912385 0.06 ENSDART00000182642
drgx
dorsal root ganglia homeobox
chr4_-_77332032 0.06 ENSDART00000168628
ENSDART00000172025
slco1f3
solute carrier organic anion transporter family, member 1F3
chr21_-_27338639 0.06 ENSDART00000130632
hif1al2
hypoxia-inducible factor 1, alpha subunit, like 2
chr1_-_47431453 0.06 ENSDART00000101104
gja5b
gap junction protein, alpha 5b
chr1_+_57151926 0.06 ENSDART00000152628
si:ch73-94k4.5
si:ch73-94k4.5
chr2_-_9646857 0.06 ENSDART00000056901
zgc:153615
zgc:153615
chr24_+_24461558 0.06 ENSDART00000182424
bhlhe22
basic helix-loop-helix family, member e22
chr1_+_56801021 0.05 ENSDART00000146545
si:ch211-1f22.3
si:ch211-1f22.3
chr25_+_5972690 0.05 ENSDART00000067517
si:ch211-11i22.4
si:ch211-11i22.4
chr2_+_38608290 0.05 ENSDART00000159066
cdh24b
cadherin 24, type 2b
chr9_-_3934963 0.05 ENSDART00000062336
ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr20_-_40754794 0.05 ENSDART00000187251
cx32.3
connexin 32.3
chr5_+_19094462 0.05 ENSDART00000190596
unc13ba
unc-13 homolog Ba (C. elegans)
chr3_+_18936009 0.05 ENSDART00000140330
si:ch211-198m1.1
si:ch211-198m1.1
chr11_+_3281899 0.05 ENSDART00000181012
mmp19
matrix metallopeptidase 19
chr24_+_41915878 0.05 ENSDART00000171523
TMEM200C
transmembrane protein 200C
chr4_+_20954929 0.05 ENSDART00000143674
nav3
neuron navigator 3
chr20_-_2949028 0.05 ENSDART00000104667
ENSDART00000193151
ENSDART00000131946
cdk19
cyclin-dependent kinase 19
chr23_-_7674902 0.05 ENSDART00000185612
ENSDART00000180524
plagl2
pleiomorphic adenoma gene-like 2
chr10_-_8197049 0.04 ENSDART00000129467
dhx29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr1_+_57208005 0.04 ENSDART00000152410
si:dkey-27j5.10
si:dkey-27j5.10
chr15_-_21132480 0.04 ENSDART00000078734
ENSDART00000157481
a2ml
alpha-2-macroglobulin-like
chr23_+_5490854 0.04 ENSDART00000175403
tulp1a
tubby like protein 1a
chr23_-_11870962 0.04 ENSDART00000143481
si:dkey-178k16.1
si:dkey-178k16.1
chr7_+_37377335 0.04 ENSDART00000111842
sall1a
spalt-like transcription factor 1a
chr10_-_7785930 0.04 ENSDART00000043961
ENSDART00000111058
mpx
myeloid-specific peroxidase
chr6_-_43677125 0.04 ENSDART00000150128
foxp1b
forkhead box P1b
chr20_-_26491567 0.04 ENSDART00000147154
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr6_-_18960105 0.04 ENSDART00000185278
ENSDART00000162968
sept9b
septin 9b
chr1_+_26071869 0.04 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr24_-_28893251 0.04 ENSDART00000042065
ENSDART00000003503
col11a1a
collagen, type XI, alpha 1a
chr4_+_54618332 0.04 ENSDART00000171824
si:ch211-227e10.2
si:ch211-227e10.2

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxb8a+hoxb8b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 3.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.8 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.6 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.9 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.8 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 1.7 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.9 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 0.6 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 2.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.4 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.2 GO:0071926 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.6 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.1 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.5 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.0 0.3 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.0 0.2 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.2 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.5 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.6 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) potassium ion homeostasis(GO:0055075) sodium ion export(GO:0071436)
0.0 0.3 GO:0031579 membrane raft organization(GO:0031579)
0.0 1.3 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.6 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.6 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.1 GO:0070375 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.1 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.7 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.7 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.1 GO:2001287 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.6 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.8 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.8 GO:0016586 RSC complex(GO:0016586)
0.1 0.5 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.8 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.2 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 2.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.9 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.5 GO:0036122 BMP binding(GO:0036122)
0.1 0.8 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.3 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0009975 cyclase activity(GO:0009975)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation