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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxc12a+hoxc12b

Z-value: 0.42

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Transcription factors associated with hoxc12a+hoxc12b

Gene Symbol Gene ID Gene Info
hoxc12a
ENSDARG00000070352 homeobox C12a
hoxc12b
ENSDARG00000103133 homeobox C12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc12bdr11_v1_chr11_+_2172335_2172335-0.272.7e-01Click!
hoxc12adr11_v1_chr23_+_36063599_36063599-0.097.3e-01Click!

Activity profile of hoxc12a+hoxc12b motif

Sorted Z-values of hoxc12a+hoxc12b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_1550709 2.19 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr8_+_52442785 1.32 ENSDART00000189958
zgc:77112
zgc:77112
chr2_-_17114852 1.22 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr7_+_46019780 1.00 ENSDART00000163991
ccne1
cyclin E1
chr18_+_18000887 0.86 ENSDART00000147797
si:ch211-212o1.2
si:ch211-212o1.2
chr10_-_31805923 0.85 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr5_-_32489796 0.78 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr9_+_22634073 0.73 ENSDART00000181822
etv5a
ets variant 5a
chr6_-_13709591 0.71 ENSDART00000151771
chpfb
chondroitin polymerizing factor b
chr6_+_2174082 0.71 ENSDART00000073936
acvr1bb
activin A receptor type 1Bb
chr15_-_28904371 0.71 ENSDART00000155154
eml2
echinoderm microtubule associated protein like 2
chr1_-_29061285 0.67 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gemin8
gem (nuclear organelle) associated protein 8
chr17_+_17764979 0.66 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr6_-_14038804 0.64 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr20_-_44576949 0.63 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr15_+_29024895 0.62 ENSDART00000141164
ENSDART00000144126
si:ch211-137a8.2
si:ch211-137a8.2
chr9_-_29039506 0.60 ENSDART00000100744
tmem177
transmembrane protein 177
chr2_-_55797318 0.60 ENSDART00000158147
calr3b
calreticulin 3b
chr8_+_23861461 0.58 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr13_+_33268657 0.58 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr2_-_6065416 0.57 ENSDART00000037698
uck2b
uridine-cytidine kinase 2b
chr13_+_8892784 0.57 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr21_-_22357985 0.57 ENSDART00000101751
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr3_+_16663373 0.56 ENSDART00000100961
zgc:55558
zgc:55558
chr11_-_6880725 0.51 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr19_+_26640096 0.50 ENSDART00000067793
ints3
integrator complex subunit 3
chr1_-_26782573 0.50 ENSDART00000090611
sh3gl2a
SH3 domain containing GRB2 like 2a, endophilin A1
chr1_-_38171648 0.50 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr15_-_20412286 0.49 ENSDART00000008589
chp2
calcineurin-like EF-hand protein 2
chr13_-_25196758 0.48 ENSDART00000184722
adka
adenosine kinase a
chr22_-_31517300 0.46 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr5_-_24542726 0.46 ENSDART00000182975
trmt2a
tRNA methyltransferase 2 homolog A
chr5_+_41477954 0.46 ENSDART00000185871
pias2
protein inhibitor of activated STAT, 2
chr5_-_54395488 0.46 ENSDART00000160781
zmynd19
zinc finger, MYND-type containing 19
chr17_+_49500820 0.45 ENSDART00000170306
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
chr3_-_27868183 0.45 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr13_+_29925397 0.45 ENSDART00000123482
cuedc2
CUE domain containing 2
chr25_+_3294150 0.45 ENSDART00000030683
tmpob
thymopoietin b
chr3_-_40254634 0.43 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr12_-_17199381 0.43 ENSDART00000193292
lipf
lipase, gastric
chr7_-_25133783 0.43 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr6_-_3992942 0.41 ENSDART00000182328
unc50
unc-50 homolog (C. elegans)
chr13_-_3936555 0.41 ENSDART00000017052
ncoa4
nuclear receptor coactivator 4
chr3_-_23575007 0.40 ENSDART00000155282
ENSDART00000087726
igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr6_-_34838397 0.40 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr11_+_43751263 0.40 ENSDART00000163843
zgc:153431
zgc:153431
chr7_-_30624435 0.39 ENSDART00000173828
rnf111
ring finger protein 111
chr6_+_27991943 0.39 ENSDART00000143974
ENSDART00000141354
ENSDART00000088914
ENSDART00000139367
amotl2a
angiomotin like 2a
chr5_-_9216758 0.39 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr22_+_10676981 0.38 ENSDART00000138016
hyal2b
hyaluronoglucosaminidase 2b
chr3_-_18737126 0.38 ENSDART00000055767
e4f1
E4F transcription factor 1
chr6_+_13207139 0.38 ENSDART00000185601
ENSDART00000182182
ino80db
INO80 complex subunit Db
chr18_-_21685055 0.36 ENSDART00000019861
mbtps1
membrane-bound transcription factor peptidase, site 1
chr20_+_34671386 0.36 ENSDART00000152836
ENSDART00000138226
elp3
elongator acetyltransferase complex subunit 3
chr12_-_11560794 0.35 ENSDART00000149098
ENSDART00000169975
plekha1b
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr2_+_31330358 0.35 ENSDART00000178066
clul1
clusterin-like 1 (retinal)
chr2_+_8261109 0.35 ENSDART00000024677
dia1a
deleted in autism 1a
chr6_-_53334259 0.33 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr10_+_15967643 0.33 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr25_-_37121335 0.33 ENSDART00000017805
nfat5a
nuclear factor of activated T cells 5a
chr13_+_38817871 0.32 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr19_+_7424347 0.32 ENSDART00000004622
sf3b4
splicing factor 3b, subunit 4
chr13_-_36050303 0.31 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr2_+_23039041 0.31 ENSDART00000056921
csnk1g2a
casein kinase 1, gamma 2a
chr18_-_31105391 0.31 ENSDART00000039495
pdcd5
programmed cell death 5
chr6_+_27992886 0.31 ENSDART00000160354
amotl2a
angiomotin like 2a
chr11_-_26832685 0.30 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr3_-_48612078 0.30 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr2_+_55199721 0.29 ENSDART00000016143
zmp:0000000521
zmp:0000000521
chr19_+_30884960 0.29 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr16_+_10429770 0.29 ENSDART00000173132
vars
valyl-tRNA synthetase
chr4_-_13156971 0.28 ENSDART00000182164
grip1
glutamate receptor interacting protein 1
chr7_+_29167744 0.28 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr2_-_20715094 0.28 ENSDART00000155439
dusp12
dual specificity phosphatase 12
chr2_-_37134169 0.27 ENSDART00000146123
ENSDART00000146533
ENSDART00000040427
elavl1a
ELAV like RNA binding protein 1a
chr5_-_31857345 0.27 ENSDART00000112546
pkn3
protein kinase N3
chr9_+_38314466 0.27 ENSDART00000048753
ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr15_-_28262632 0.26 ENSDART00000134601
ENSDART00000175022
prpf8
pre-mRNA processing factor 8
chr24_-_24796583 0.26 ENSDART00000144791
ENSDART00000146570
pde7a
phosphodiesterase 7A
chr6_+_3730843 0.25 ENSDART00000019630
FO704755.1

chr6_+_42338309 0.25 ENSDART00000015277
gpx1b
glutathione peroxidase 1b
chr24_-_17029374 0.25 ENSDART00000039267
ptgdsb.1
prostaglandin D2 synthase b, tandem duplicate 1
chr3_+_31058464 0.24 ENSDART00000153381
si:dkey-66i24.7
si:dkey-66i24.7
chr4_-_73488406 0.24 ENSDART00000115002
si:ch73-266f23.1
si:ch73-266f23.1
chr5_+_32490238 0.23 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr15_+_44093286 0.23 ENSDART00000114352
zgc:112998
zgc:112998
chr15_-_23942861 0.23 ENSDART00000002824
appbp2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr8_-_8346023 0.23 ENSDART00000164731
ENSDART00000188259
tsr2
TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
chr25_-_7670616 0.23 ENSDART00000131583
ENSDART00000142794
bet1l
Bet1 golgi vesicular membrane trafficking protein-like
chr5_-_31856681 0.22 ENSDART00000187817
pkn3
protein kinase N3
chr1_+_31019165 0.22 ENSDART00000102210
itga6b
integrin, alpha 6b
chr22_-_10440688 0.22 ENSDART00000111962
nol8
nucleolar protein 8
chr7_+_30240791 0.21 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr16_-_12060488 0.21 ENSDART00000188733
si:ch211-69g19.2
si:ch211-69g19.2
chr2_-_37874647 0.20 ENSDART00000039386
zgc:66427
zgc:66427
chr19_-_7272921 0.19 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
rxrba
retinoid x receptor, beta a
chr14_+_2487672 0.19 ENSDART00000170629
ENSDART00000123063
fgf18a
fibroblast growth factor 18a
chr15_+_5132439 0.19 ENSDART00000010350
pgm2l1
phosphoglucomutase 2-like 1
chr7_+_10563017 0.19 ENSDART00000193520
ENSDART00000173125
zfand6
zinc finger, AN1-type domain 6
chr7_+_24522308 0.18 ENSDART00000173542
btr09
bloodthirsty-related gene family, member 9
chr2_-_18830722 0.18 ENSDART00000165330
ENSDART00000165698
pbx1a
pre-B-cell leukemia homeobox 1a
chr25_-_7670391 0.17 ENSDART00000044970
bet1l
Bet1 golgi vesicular membrane trafficking protein-like
chr6_-_28222592 0.17 ENSDART00000131126
bcl6a
B-cell CLL/lymphoma 6a (zinc finger protein 51)
chr15_-_19443997 0.16 ENSDART00000114936
esamb
endothelial cell adhesion molecule b
chr22_+_17286841 0.16 ENSDART00000133176
FAM163A
si:dkey-171o17.8
chr15_+_43799258 0.15 ENSDART00000122238
tyr
tyrosinase
chr8_-_65189 0.15 ENSDART00000168412
hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
chr20_-_19530751 0.14 ENSDART00000148574
eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr16_+_38659475 0.13 ENSDART00000023238
emc2
ER membrane protein complex subunit 2
chr5_-_26764298 0.13 ENSDART00000189373
rnf181
ring finger protein 181
chr18_-_21748808 0.13 ENSDART00000079253
pskh1
protein serine kinase H1
chr2_+_54696042 0.12 ENSDART00000074270
ankrd12
ankyrin repeat domain 12
chr16_+_11242443 0.12 ENSDART00000024935
gsk3ab
glycogen synthase kinase 3 alpha b
chr24_-_24797455 0.11 ENSDART00000138741
pde7a
phosphodiesterase 7A
chr16_-_6205790 0.10 ENSDART00000038495
ctnnb1
catenin (cadherin-associated protein), beta 1
chr3_+_37787229 0.10 ENSDART00000075028
rps11
ribosomal protein S11
chr20_-_47422469 0.10 ENSDART00000021341
kif3ca
kinesin family member 3Ca
chr9_-_10145795 0.10 ENSDART00000004745
ENSDART00000143295
hnmt
histamine N-methyltransferase
chr14_-_26425416 0.09 ENSDART00000088690
lman2
lectin, mannose-binding 2
chr25_-_7887274 0.09 ENSDART00000157276
si:ch73-151m17.5
si:ch73-151m17.5
chr18_+_3140682 0.09 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr7_+_27898091 0.09 ENSDART00000186451
ENSDART00000173510
tub
tubby bipartite transcription factor
chr22_+_30137374 0.08 ENSDART00000187808
add3a
adducin 3 (gamma) a
chr13_+_45431660 0.08 ENSDART00000099950
syf2
SYF2 pre-mRNA-splicing factor
chr15_+_34675660 0.08 ENSDART00000009127
lta
lymphotoxin alpha (TNF superfamily, member 1)
chr9_-_38399432 0.08 ENSDART00000148268
znf142
zinc finger protein 142
chr5_-_21065094 0.07 ENSDART00000143785
si:dkey-13n15.2
si:dkey-13n15.2
chr17_-_23727978 0.07 ENSDART00000079600
minpp1a
multiple inositol-polyphosphate phosphatase 1a
chr4_-_73520581 0.07 ENSDART00000171513
si:ch73-266f23.1
si:ch73-266f23.1
chr2_+_30103285 0.07 ENSDART00000019417
dnajb6a
DnaJ (Hsp40) homolog, subfamily B, member 6a
chr9_-_9242777 0.06 ENSDART00000021191
u2af1
U2 small nuclear RNA auxiliary factor 1
chr24_-_6898302 0.06 ENSDART00000158646
dpp6a
dipeptidyl-peptidase 6a
chr12_-_30777540 0.06 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr24_+_34069675 0.06 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr9_+_20483846 0.05 ENSDART00000192067
ENSDART00000145111
parp4
poly (ADP-ribose) polymerase family, member 4
chr3_+_23691847 0.05 ENSDART00000078453
hoxb7a
homeobox B7a
chr3_-_10749691 0.05 ENSDART00000183088
CU210890.1

chr16_-_47426482 0.05 ENSDART00000148631
ENSDART00000149723
sept7b
septin 7b
chr6_-_54816567 0.05 ENSDART00000150079
tnni1b
troponin I type 1b (skeletal, slow)
chr14_+_32022272 0.05 ENSDART00000105760
zic6
zic family member 6
chr18_+_31280984 0.04 ENSDART00000170285
ENSDART00000150608
ENSDART00000159720
def8
differentially expressed in FDCP 8 homolog (mouse)
chr16_-_33806390 0.04 ENSDART00000160671
rspo1
R-spondin 1
chr20_-_8094718 0.04 ENSDART00000122902
si:ch211-232i5.3
si:ch211-232i5.3
chr20_+_46183505 0.04 ENSDART00000060799
taar13b
trace amine associated receptor 13b
chr11_+_7214353 0.04 ENSDART00000156764
nwd1
NACHT and WD repeat domain containing 1
chr24_-_21913426 0.04 ENSDART00000081178
c1qtnf9
C1q and TNF related 9
chr12_-_9123352 0.04 ENSDART00000149655
adam8b
ADAM metallopeptidase domain 8b
chr7_-_32833153 0.04 ENSDART00000099871
ENSDART00000099872
slc17a6b
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr23_-_4855122 0.03 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr23_-_39849155 0.03 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr1_-_8101495 0.03 ENSDART00000161938
si:dkeyp-9d4.3
si:dkeyp-9d4.3
chr13_-_3351708 0.03 ENSDART00000042875
si:ch73-193i2.2
si:ch73-193i2.2
chr4_-_46915962 0.03 ENSDART00000169555
si:ch211-134c10.1
si:ch211-134c10.1
chr3_-_15734358 0.03 ENSDART00000137325
mvp
major vault protein
chr16_+_42471455 0.03 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr22_-_9736050 0.02 ENSDART00000152919
si:dkey-286j17.4
si:dkey-286j17.4
chr7_-_2116512 0.02 ENSDART00000098148
si:cabz01007802.1
si:cabz01007802.1
chr19_-_10425140 0.02 ENSDART00000145319
si:ch211-171h4.3
si:ch211-171h4.3
chr5_+_36611128 0.02 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr9_+_54290896 0.02 ENSDART00000149175
pou4f3
POU class 4 homeobox 3
chr23_-_12014931 0.02 ENSDART00000134652
si:dkey-178k16.1
si:dkey-178k16.1
chr1_+_58424507 0.02 ENSDART00000114197
si:ch73-236c18.3
si:ch73-236c18.3
chr23_+_33752275 0.02 ENSDART00000007260
si:ch211-210c8.6
si:ch211-210c8.6
chr14_-_32866351 0.01 ENSDART00000166133
ENSDART00000172545
ube2a
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr1_+_36437585 0.01 ENSDART00000189182
pou4f2
POU class 4 homeobox 2
chr13_+_39182099 0.01 ENSDART00000131434
fam135a
family with sequence similarity 135, member A
chr11_-_18557929 0.01 ENSDART00000110882
ENSDART00000181381
ENSDART00000189312
dido1
death inducer-obliterator 1
chr4_-_38259998 0.01 ENSDART00000172389
znf1093
zinc finger protein 1093
chr18_+_33264609 0.01 ENSDART00000050639
v2ra20
vomeronasal 2 receptor, a20
chr21_-_4539899 0.01 ENSDART00000112460
dolk
dolichol kinase
chr22_+_10440991 0.01 ENSDART00000064805
cenpp
centromere protein P
chr22_+_15308526 0.01 ENSDART00000188280
CU104797.1

chr1_-_34612613 0.00 ENSDART00000004361
klf5a
Kruppel-like factor 5a
chr10_-_15910974 0.00 ENSDART00000148169
pip5k1ba
phosphatidylinositol-4-phosphate 5-kinase, type I, beta a
chr17_-_51199219 0.00 ENSDART00000154403
paplna
papilin a, proteoglycan-like sulfated glycoprotein
chr12_+_46696867 0.00 ENSDART00000152928
ENSDART00000153445
ENSDART00000123357
ENSDART00000152880
ENSDART00000123834
ENSDART00000174765
ENSDART00000189923
exoc7
exocyst complex component 7

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc12a+hoxc12b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 0.4 GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.(GO:0002926)
0.1 1.2 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 1.4 GO:0035108 limb morphogenesis(GO:0035108)
0.1 0.5 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.7 GO:0035909 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1 0.5 GO:0044209 AMP salvage(GO:0044209)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.3 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.1 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0051299 mitotic centrosome separation(GO:0007100) centrosome separation(GO:0051299)
0.0 0.4 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.6 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.2 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.0 0.1 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.0 0.3 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.5 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.3 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 1.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.6 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.7 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.0 GO:0051044 regulation of cellular extravasation(GO:0002691) positive regulation of cellular extravasation(GO:0002693) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 0.7 GO:0032797 SMN complex(GO:0032797)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.8 GO:0030904 retromer complex(GO:0030904)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 1.2 GO:0005657 replication fork(GO:0005657)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.0 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.7 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 1.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.2 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.5 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination