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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxd12a

Z-value: 0.48

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Transcription factors associated with hoxd12a

Gene Symbol Gene ID Gene Info
hoxd12a
ENSDARG00000059263 homeobox D12a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd12adr11_v1_chr9_-_1986014_19860140.465.7e-02Click!

Activity profile of hoxd12a motif

Sorted Z-values of hoxd12a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_1550709 1.41 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr24_+_34069675 0.93 ENSDART00000143995
si:ch211-190p8.2
si:ch211-190p8.2
chr21_-_43665537 0.92 ENSDART00000157610
si:dkey-229d11.3
si:dkey-229d11.3
chr23_+_17926279 0.73 ENSDART00000012540
chia.4
chitinase, acidic.4
chr22_-_11078988 0.70 ENSDART00000126664
ENSDART00000006927
use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr2_-_6065416 0.69 ENSDART00000037698
uck2b
uridine-cytidine kinase 2b
chr8_+_52442785 0.61 ENSDART00000189958
zgc:77112
zgc:77112
chr24_-_5713799 0.56 ENSDART00000137293
dia1b
deleted in autism 1b
chr6_-_13709591 0.53 ENSDART00000151771
chpfb
chondroitin polymerizing factor b
chr23_-_14769523 0.52 ENSDART00000054909
gss
glutathione synthetase
chr3_+_11072958 0.52 ENSDART00000158899
mrps7
mitochondrial ribosomal protein S7
chr7_+_55292959 0.50 ENSDART00000147539
ENSDART00000073555
ctu2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr17_+_17764979 0.49 ENSDART00000105013
alkbh1
alkB homolog 1, histone H2A dioxygenase
chr19_+_28291062 0.48 ENSDART00000163382
lpcat1
lysophosphatidylcholine acyltransferase 1
chr6_-_14038804 0.48 ENSDART00000184606
ENSDART00000184609
etv5b
ets variant 5b
chr19_+_28291376 0.48 ENSDART00000139433
ENSDART00000103855
lpcat1
lysophosphatidylcholine acyltransferase 1
chr18_+_18000887 0.45 ENSDART00000147797
si:ch211-212o1.2
si:ch211-212o1.2
chr19_-_1948236 0.45 ENSDART00000163344
znrf2a
zinc and ring finger 2a
chr6_+_3730843 0.42 ENSDART00000019630
FO704755.1

chr13_+_35472803 0.41 ENSDART00000011583
mkks
McKusick-Kaufman syndrome
chr2_+_22409249 0.41 ENSDART00000182915
zgc:56628
zgc:56628
chr4_+_9279515 0.40 ENSDART00000048707
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr6_-_18228358 0.40 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr5_-_31856681 0.40 ENSDART00000187817
pkn3
protein kinase N3
chr19_-_7321221 0.40 ENSDART00000092375
oxr1b
oxidation resistance 1b
chr21_-_22357985 0.40 ENSDART00000101751
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr24_-_31223232 0.39 ENSDART00000164155
alg14
ALG14, UDP-N-acetylglucosaminyltransferase subunit
chr25_+_31122806 0.37 ENSDART00000067039
rassf8a
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8a
chr5_-_32489796 0.37 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr25_-_21066136 0.37 ENSDART00000109520
fbxl14a
F-box and leucine-rich repeat protein 14a
chr20_-_26391958 0.37 ENSDART00000078062
armt1
acidic residue methyltransferase 1
chr15_-_20412286 0.37 ENSDART00000008589
chp2
calcineurin-like EF-hand protein 2
chr1_-_26782573 0.37 ENSDART00000090611
sh3gl2a
SH3 domain containing GRB2 like 2a, endophilin A1
chr3_-_27868183 0.37 ENSDART00000185812
abat
4-aminobutyrate aminotransferase
chr9_-_29039506 0.36 ENSDART00000100744
tmem177
transmembrane protein 177
chr25_+_3788443 0.36 ENSDART00000189747
chid1
chitinase domain containing 1
chr22_-_31517300 0.35 ENSDART00000164799
slc6a6b
solute carrier family 6 (neurotransmitter transporter), member 6b
chr11_-_6880725 0.35 ENSDART00000007204
ddx49
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr22_+_10676981 0.35 ENSDART00000138016
hyal2b
hyaluronoglucosaminidase 2b
chr13_-_17860307 0.35 ENSDART00000135920
ENSDART00000054579
march8
membrane-associated ring finger (C3HC4) 8
chr18_+_8812549 0.34 ENSDART00000017619
impdh1a
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr8_+_23861461 0.34 ENSDART00000037109
srpk1a
SRSF protein kinase 1a
chr20_-_45772306 0.33 ENSDART00000062092
trmt6
tRNA methyltransferase 6 homolog (S. cerevisiae)
chr3_-_50147160 0.31 ENSDART00000191341
btr02
bloodthirsty-related gene family, member 2
chr4_-_13156971 0.31 ENSDART00000182164
grip1
glutamate receptor interacting protein 1
chr2_-_55797318 0.31 ENSDART00000158147
calr3b
calreticulin 3b
chr3_+_25166805 0.31 ENSDART00000077493
TST
zgc:162544
chr8_-_12432604 0.31 ENSDART00000133350
ENSDART00000140699
ENSDART00000101174
traf1
TNF receptor-associated factor 1
chr21_-_26406244 0.30 ENSDART00000137312
ENSDART00000077200
eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr7_-_55051692 0.30 ENSDART00000170637
tpcn2
two pore segment channel 2
chr10_-_14943281 0.30 ENSDART00000143608
smad2
SMAD family member 2
chr10_-_31805923 0.30 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr15_-_28904371 0.29 ENSDART00000155154
eml2
echinoderm microtubule associated protein like 2
chr20_-_44576949 0.29 ENSDART00000148639
ubxn2a
UBX domain protein 2A
chr9_+_500052 0.29 ENSDART00000166707
CU984600.1

chr5_+_32490595 0.29 ENSDART00000165417
ndor1
NADPH dependent diflavin oxidoreductase 1
chr9_+_41080029 0.29 ENSDART00000141179
ENSDART00000019289
zgc:136439
zgc:136439
chr13_+_35856463 0.28 ENSDART00000171056
ENSDART00000017202
kcnk1b
potassium channel, subfamily K, member 1b
chr25_-_34973211 0.28 ENSDART00000045177
cdk10
cyclin-dependent kinase 10
chr25_+_3294150 0.28 ENSDART00000030683
tmpob
thymopoietin b
chr23_+_39611688 0.28 ENSDART00000034690
otud3
OTU deubiquitinase 3
chr16_+_32014552 0.27 ENSDART00000047570
mboat7
membrane bound O-acyltransferase domain containing 7
chr11_-_36040549 0.27 ENSDART00000112684
setmar
SET domain and mariner transposase fusion gene
chr1_-_38171648 0.27 ENSDART00000137451
ENSDART00000047159
hmgb2a
high mobility group box 2a
chr18_-_41161828 0.27 ENSDART00000114993
CABZ01005876.1

chr6_-_30485009 0.27 ENSDART00000025698
zgc:153311
zgc:153311
chr5_+_29714786 0.27 ENSDART00000148314
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr7_-_41014773 0.27 ENSDART00000013785
insig1
insulin induced gene 1
chr14_+_8940326 0.26 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr22_+_20169352 0.26 ENSDART00000169055
ENSDART00000061617
hmg20b
high mobility group 20B
chr2_+_26240339 0.25 ENSDART00000191006
palm1b
paralemmin 1b
chr5_-_24542726 0.25 ENSDART00000182975
trmt2a
tRNA methyltransferase 2 homolog A
chr24_+_21174851 0.25 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr5_-_23696926 0.25 ENSDART00000021462
rnf128a
ring finger protein 128a
chr17_+_30843881 0.25 ENSDART00000149600
ENSDART00000148547
tpp1
tripeptidyl peptidase I
chr20_+_405811 0.25 ENSDART00000149311
gpr63
G protein-coupled receptor 63
chr22_-_9860792 0.25 ENSDART00000155908
si:dkey-253d23.2
si:dkey-253d23.2
chr20_-_154989 0.25 ENSDART00000064542
rpf2
ribosome production factor 2 homolog
chr3_+_16663373 0.24 ENSDART00000100961
zgc:55558
zgc:55558
chr6_+_13207139 0.24 ENSDART00000185601
ENSDART00000182182
ino80db
INO80 complex subunit Db
chr3_-_26191960 0.24 ENSDART00000113843
ypel3
yippee-like 3
chr5_+_23598364 0.24 ENSDART00000132155
kat5b
K(lysine) acetyltransferase 5b
chr5_+_29715040 0.24 ENSDART00000192563
ddx31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr11_+_43751263 0.23 ENSDART00000163843
zgc:153431
zgc:153431
chr14_+_16287968 0.23 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr16_+_33143503 0.23 ENSDART00000058471
ENSDART00000179385
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr24_+_30392834 0.23 ENSDART00000162555
dpyda.1
dihydropyrimidine dehydrogenase a, tandem duplicate 1
chr19_+_42227400 0.23 ENSDART00000131574
ENSDART00000135436
jtb
jumping translocation breakpoint
chr21_-_13055195 0.22 ENSDART00000133517
myorg
myogenesis regulating glycosidase (putative)
chr17_+_1632294 0.22 ENSDART00000191959
srp14
signal recognition particle 14
chr13_+_21768447 0.22 ENSDART00000100941
chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr6_-_34838397 0.22 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr7_-_25133783 0.22 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr21_-_3007412 0.22 ENSDART00000190839
CKS2
zgc:86839
chr9_-_38399432 0.21 ENSDART00000148268
znf142
zinc finger protein 142
chr2_+_371759 0.21 ENSDART00000153788
si:dkey-33c14.7
si:dkey-33c14.7
chr2_+_31330358 0.21 ENSDART00000178066
clul1
clusterin-like 1 (retinal)
chr22_-_10440688 0.21 ENSDART00000111962
nol8
nucleolar protein 8
chr4_-_25271455 0.20 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr21_-_36396334 0.20 ENSDART00000183627
mrpl22
mitochondrial ribosomal protein L22
chr16_-_33650578 0.20 ENSDART00000058460
utp11l
UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
chr11_-_21303946 0.19 ENSDART00000185786
RASSF5
si:dkey-85p17.3
chr2_+_26240631 0.19 ENSDART00000129895
palm1b
paralemmin 1b
chr11_-_26832685 0.19 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr11_+_25560632 0.19 ENSDART00000033914
mbd1b
methyl-CpG binding domain protein 1b
chr17_+_49500820 0.19 ENSDART00000170306
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
chr5_+_32490238 0.19 ENSDART00000191839
ndor1
NADPH dependent diflavin oxidoreductase 1
chr2_-_34138064 0.19 ENSDART00000133381
cenpl
centromere protein L
chr7_+_42206847 0.19 ENSDART00000149250
phkb
phosphorylase kinase, beta
chr2_-_13254594 0.18 ENSDART00000155671
kdsr
3-ketodihydrosphingosine reductase
chr16_-_30655980 0.18 ENSDART00000146508
ldlrad4b
low density lipoprotein receptor class A domain containing 4b
chr16_+_4078240 0.18 ENSDART00000160890
inpp5b
inositol polyphosphate-5-phosphatase B
chr1_+_41466011 0.18 ENSDART00000135280
paip2b
poly(A) binding protein interacting protein 2B
chr23_-_27505825 0.18 ENSDART00000137229
ENSDART00000013797
asb8
ankyrin repeat and SOCS box containing 8
chr2_+_55199721 0.18 ENSDART00000016143
zmp:0000000521
zmp:0000000521
chr12_-_11560794 0.18 ENSDART00000149098
ENSDART00000169975
plekha1b
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1b
chr10_+_2582254 0.18 ENSDART00000016103
nxnl2
nucleoredoxin like 2
chr24_-_16979728 0.18 ENSDART00000005331
klhl15
kelch-like family member 15
chr7_+_29167744 0.18 ENSDART00000076345
slc38a8b
solute carrier family 38, member 8b
chr24_-_16980337 0.17 ENSDART00000183812
klhl15
kelch-like family member 15
chr17_+_31221761 0.17 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr24_-_26632171 0.17 ENSDART00000008374
ENSDART00000017384
tnikb
TRAF2 and NCK interacting kinase b
chr5_-_26764880 0.17 ENSDART00000140392
ENSDART00000134728
rnf181
ring finger protein 181
chr20_-_19530751 0.17 ENSDART00000148574
eif2b4
eukaryotic translation initiation factor 2B, subunit 4 delta
chr12_-_17199381 0.17 ENSDART00000193292
lipf
lipase, gastric
chr7_-_26125092 0.16 ENSDART00000079364
snapc2
small nuclear RNA activating complex, polypeptide 2
chr14_+_30568961 0.16 ENSDART00000184303
mrpl11
mitochondrial ribosomal protein L11
chr3_-_40254634 0.16 ENSDART00000154562
top3a
DNA topoisomerase III alpha
chr5_-_32396929 0.16 ENSDART00000023977
fbxw2
F-box and WD repeat domain containing 2
chr23_-_4933508 0.16 ENSDART00000137578
ENSDART00000141196
ngfa
nerve growth factor a (beta polypeptide)
chr19_-_25081711 0.16 ENSDART00000058513
xkr8.3
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 3
chr10_+_25947946 0.15 ENSDART00000064393
ufm1
ubiquitin-fold modifier 1
chr19_+_19989380 0.15 ENSDART00000142841
osbpl3a
oxysterol binding protein-like 3a
chr19_-_31007417 0.15 ENSDART00000048144
rbbp4
retinoblastoma binding protein 4
chr6_+_32326074 0.15 ENSDART00000042134
ENSDART00000181177
dock7
dedicator of cytokinesis 7
chr2_-_13254821 0.15 ENSDART00000022621
kdsr
3-ketodihydrosphingosine reductase
chr15_-_19443997 0.15 ENSDART00000114936
esamb
endothelial cell adhesion molecule b
chr23_-_27506161 0.15 ENSDART00000145007
asb8
ankyrin repeat and SOCS box containing 8
chr24_-_24796583 0.14 ENSDART00000144791
ENSDART00000146570
pde7a
phosphodiesterase 7A
chr4_-_18851365 0.14 ENSDART00000021782
mcat
malonyl CoA:ACP acyltransferase (mitochondrial)
chr17_+_38295847 0.14 ENSDART00000008532
mbip
MAP3K12 binding inhibitory protein 1
chr13_-_36050303 0.14 ENSDART00000134955
ENSDART00000139087
lgmn
legumain
chr13_-_34862452 0.14 ENSDART00000134573
ENSDART00000047552
sptlc3
serine palmitoyltransferase, long chain base subunit 3
chr3_-_48612078 0.14 ENSDART00000169923
ndel1b
nudE neurodevelopment protein 1-like 1b
chr5_+_23599259 0.14 ENSDART00000138902
kat5b
K(lysine) acetyltransferase 5b
chr24_+_21174523 0.14 ENSDART00000183849
naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr9_-_2892045 0.13 ENSDART00000137201
cdca7a
cell division cycle associated 7a
chr24_-_36175365 0.13 ENSDART00000065338
pak1ip1
PAK1 interacting protein 1
chr6_-_53334259 0.13 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr18_+_31280984 0.13 ENSDART00000170285
ENSDART00000150608
ENSDART00000159720
def8
differentially expressed in FDCP 8 homolog (mouse)
chr2_-_26499842 0.13 ENSDART00000186929
BX569796.1

chr19_-_7272921 0.13 ENSDART00000102075
ENSDART00000132887
ENSDART00000130234
ENSDART00000193535
ENSDART00000136528
rxrba
retinoid x receptor, beta a
chr13_+_29925397 0.13 ENSDART00000123482
cuedc2
CUE domain containing 2
chr2_-_5728843 0.13 ENSDART00000014020
sst2
somatostatin 2
chr16_+_10429770 0.12 ENSDART00000173132
vars
valyl-tRNA synthetase
chr7_+_14005111 0.12 ENSDART00000187365
furina
furin (paired basic amino acid cleaving enzyme) a
chr11_+_25560072 0.12 ENSDART00000124131
ENSDART00000147179
mbd1b
methyl-CpG binding domain protein 1b
chr5_-_69499486 0.11 ENSDART00000023983
ENSDART00000180293
psat1
phosphoserine aminotransferase 1
chr16_+_4078608 0.11 ENSDART00000166241
inpp5b
inositol polyphosphate-5-phosphatase B
chr1_+_41465771 0.11 ENSDART00000010211
paip2b
poly(A) binding protein interacting protein 2B
chr22_-_9901788 0.11 ENSDART00000141526
znf991
zinc finger protein 991
chr19_+_29808699 0.11 ENSDART00000051799
ENSDART00000164205
hdac1
histone deacetylase 1
chr15_+_2857556 0.11 ENSDART00000157758
mre11a
MRE11 homolog A, double strand break repair nuclease
chr18_+_3140682 0.11 ENSDART00000166382
clns1a
chloride channel, nucleotide-sensitive, 1A
chr16_+_33144306 0.11 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr25_-_37084032 0.10 ENSDART00000025494
hprt1l
hypoxanthine phosphoribosyltransferase 1, like
chr15_-_2754056 0.10 ENSDART00000129380
ppp5c
protein phosphatase 5, catalytic subunit
chr1_+_42225060 0.10 ENSDART00000138740
ENSDART00000101306
ctnna2
catenin (cadherin-associated protein), alpha 2
chr19_+_29808471 0.10 ENSDART00000186428
hdac1
histone deacetylase 1
chr9_+_55321322 0.10 ENSDART00000111111
ENSDART00000191579
nlgn4b
neuroligin 4b
chr12_+_46696867 0.10 ENSDART00000152928
ENSDART00000153445
ENSDART00000123357
ENSDART00000152880
ENSDART00000123834
ENSDART00000174765
ENSDART00000189923
exoc7
exocyst complex component 7
chr7_-_73846995 0.10 ENSDART00000188079
FP236812.4

chr25_-_37121335 0.09 ENSDART00000017805
nfat5a
nuclear factor of activated T cells 5a
chr15_-_5467477 0.09 ENSDART00000123839
arrb1
arrestin, beta 1
chr10_-_41397663 0.09 ENSDART00000158038
gpat4
glycerol-3-phosphate acyltransferase 4
chr9_-_2892250 0.09 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr18_+_13275735 0.09 ENSDART00000148127
plcg2
phospholipase C, gamma 2
chr19_+_3840955 0.09 ENSDART00000172305
lsm10
LSM10, U7 small nuclear RNA associated
chr19_+_30884960 0.09 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
yars
tyrosyl-tRNA synthetase
chr15_+_5132439 0.09 ENSDART00000010350
pgm2l1
phosphoglucomutase 2-like 1
chr6_+_49742164 0.08 ENSDART00000024578
npepl1
aminopeptidase like 1
chr7_-_30624435 0.08 ENSDART00000173828
rnf111
ring finger protein 111
chr7_+_30240791 0.08 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr7_-_42206720 0.08 ENSDART00000110907
itfg1
integrin alpha FG-GAP repeat containing 1
chr11_+_7214353 0.08 ENSDART00000156764
nwd1
NACHT and WD repeat domain containing 1
chr4_-_73520581 0.08 ENSDART00000171513
si:ch73-266f23.1
si:ch73-266f23.1
chr3_-_34599662 0.07 ENSDART00000055259
nmrk1
nicotinamide riboside kinase 1
chr6_-_57476465 0.07 ENSDART00000128065
ddx27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr23_+_4226341 0.07 ENSDART00000012445
zgc:113278
zgc:113278
chr19_+_30885258 0.07 ENSDART00000143394
yars
tyrosyl-tRNA synthetase
chr24_+_21540842 0.07 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr1_+_42224769 0.07 ENSDART00000177496
ENSDART00000184778
ENSDART00000110860
ctnna2
catenin (cadherin-associated protein), alpha 2
chr16_+_42471455 0.07 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr16_-_12060488 0.06 ENSDART00000188733
si:ch211-69g19.2
si:ch211-69g19.2
chr14_+_33507608 0.06 ENSDART00000038128
mcts1
malignant T cell amplified sequence 1
chr6_+_52853384 0.06 ENSDART00000174155
ENSDART00000164391
BX957318.1

chr7_+_20524064 0.06 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr16_-_24561354 0.06 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr11_+_6881001 0.06 ENSDART00000170331
klhl26
kelch-like family member 26
chr7_+_31120766 0.06 ENSDART00000173703
tjp1a
tight junction protein 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd12a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.5 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.1 0.4 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.3 GO:0036315 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.3 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.5 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.6 GO:0044211 CTP salvage(GO:0044211)
0.1 0.3 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.4 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 0.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.7 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.2 GO:0019860 uracil catabolic process(GO:0006212) uracil metabolic process(GO:0019860)
0.0 0.4 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.4 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:2000290 regulation of myotome development(GO:2000290)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.5 GO:0021979 hypothalamus cell differentiation(GO:0021979) limb morphogenesis(GO:0035108)
0.0 0.5 GO:1901655 cellular response to ketone(GO:1901655)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.6 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:0060300 microglial cell activation(GO:0001774) regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.6 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.5 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.1 0.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.5 GO:0043295 glutathione binding(GO:0043295)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.1 GO:0008061 chitin binding(GO:0008061)
0.1 0.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0002058 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.6 GO:2001069 glycogen binding(GO:2001069)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.5 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0071617 lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0008483 transaminase activity(GO:0008483)
0.0 0.0 GO:0030623 U5 snRNA binding(GO:0030623)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.3 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase