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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for hoxd4a

Z-value: 0.39

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Transcription factors associated with hoxd4a

Gene Symbol Gene ID Gene Info
hoxd4a
ENSDARG00000059276 homeobox D4a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxd4adr11_v1_chr9_-_1951144_19511440.371.3e-01Click!

Activity profile of hoxd4a motif

Sorted Z-values of hoxd4a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_31868268 0.99 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr25_-_10503043 0.86 ENSDART00000155404
cox8b
cytochrome c oxidase subunit 8b
chr22_+_38037530 0.82 ENSDART00000012212
commd2
COMM domain containing 2
chr3_+_24361096 0.71 ENSDART00000132387
pvalb6
parvalbumin 6
chr20_+_36628059 0.69 ENSDART00000062898
ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
chr3_-_49382896 0.68 ENSDART00000169115
si:ch73-167f10.1
si:ch73-167f10.1
chr9_+_48219111 0.67 ENSDART00000111225
ENSDART00000145972
ccdc173
coiled-coil domain containing 173
chr12_-_990149 0.63 ENSDART00000054367
kdelr2b
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr11_+_25259058 0.63 ENSDART00000154109
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr16_+_26017360 0.60 ENSDART00000149466
prss59.2
protease, serine, 59, tandem duplicate 2
chr5_-_61970674 0.59 ENSDART00000143161
znf541
zinc finger protein 541
chr2_+_16160906 0.59 ENSDART00000135783
selenoj
selenoprotein J
chr15_-_45110011 0.58 ENSDART00000182047
ENSDART00000188662
CABZ01072607.1

chr12_+_3871452 0.55 ENSDART00000066546
nif3l1
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
chr5_+_42400777 0.54 ENSDART00000183114
BX548073.8

chr19_-_1855368 0.53 ENSDART00000029646
rplp1
ribosomal protein, large, P1
chr17_-_39772999 0.53 ENSDART00000155727
pimr60
Pim proto-oncogene, serine/threonine kinase, related 60
chr6_-_2627488 0.53 ENSDART00000044089
ENSDART00000158333
ENSDART00000155109
hyi
hydroxypyruvate isomerase
chr2_+_2181709 0.52 ENSDART00000092763
ENSDART00000148553
ccdc13
coiled-coil domain containing 13
chr23_+_39695827 0.52 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr23_+_24085531 0.49 ENSDART00000139710
ttll10
tubulin tyrosine ligase-like family, member 10
chr1_+_50921266 0.49 ENSDART00000006538
otx2a
orthodenticle homeobox 2a
chr23_-_42752387 0.46 ENSDART00000149781
si:ch73-217n20.1
si:ch73-217n20.1
chr5_-_18924834 0.45 ENSDART00000041371
poli
polymerase (DNA directed) iota
chr1_+_44003654 0.45 ENSDART00000131337
si:dkey-22i16.10
si:dkey-22i16.10
chr3_+_55031685 0.44 ENSDART00000132587
mpg
N-methylpurine DNA glycosylase
chr10_-_43771447 0.44 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr23_+_19813677 0.42 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr5_+_26847190 0.42 ENSDART00000076742
imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr19_+_45962016 0.42 ENSDART00000169710
utp23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr5_-_19394440 0.41 ENSDART00000163771
foxn4
forkhead box N4
chr7_+_65309738 0.41 ENSDART00000169228
vat1l
vesicle amine transport 1-like
chr20_-_29474859 0.41 ENSDART00000152906
ENSDART00000045249
scg5
secretogranin V
chr20_-_16171297 0.39 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr24_+_37902687 0.39 ENSDART00000042273
ccdc78
coiled-coil domain containing 78
chr5_+_23597144 0.38 ENSDART00000143929
ENSDART00000142420
ENSDART00000032909
kat5b
K(lysine) acetyltransferase 5b
chr20_-_438646 0.38 ENSDART00000009196
ufl1
UFM1-specific ligase 1
chr4_+_16885854 0.37 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr7_-_59311165 0.37 ENSDART00000171105
m1ap
meiosis 1 associated protein
chr4_-_74892355 0.37 ENSDART00000188725
PHF21B
PHD finger protein 21B
chr6_+_49053319 0.37 ENSDART00000124524
sycp1
synaptonemal complex protein 1
chr24_+_20536056 0.37 ENSDART00000082082
gars
glycyl-tRNA synthetase
chr24_-_37640705 0.36 ENSDART00000066583
zgc:112496
zgc:112496
chr2_+_54389750 0.36 ENSDART00000189236
rab12
RAB12, member RAS oncogene family
chr24_+_21621654 0.36 ENSDART00000002595
rpl21
ribosomal protein L21
chr19_+_43297546 0.35 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr7_+_22657566 0.35 ENSDART00000141048
ponzr5
plac8 onzin related protein 5
chr22_+_7439186 0.35 ENSDART00000190667
zgc:92041
zgc:92041
chr7_-_41512999 0.34 ENSDART00000173577
si:dkey-10f23.2
si:dkey-10f23.2
chr15_+_42285643 0.33 ENSDART00000152731
scaf4b
SR-related CTD-associated factor 4b
chr20_+_30939178 0.33 ENSDART00000062556
sod2
superoxide dismutase 2, mitochondrial
chr4_+_14900042 0.32 ENSDART00000018261
akr1b1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr14_-_32089117 0.32 ENSDART00000158014
si:ch211-69b22.5
si:ch211-69b22.5
chr2_+_33726862 0.32 ENSDART00000146745
si:dkey-31m5.5
si:dkey-31m5.5
chr17_-_24680965 0.32 ENSDART00000154880
arhgef33
Rho guanine nucleotide exchange factor (GEF) 33
chr5_+_24882633 0.31 ENSDART00000111302
rhbdd3
rhomboid domain containing 3
chr7_-_27038488 0.30 ENSDART00000052731
ENSDART00000191382
nucb2a
nucleobindin 2a
chr12_+_20352400 0.29 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr1_-_45662774 0.29 ENSDART00000042158
serhl
serine hydrolase-like
chr25_+_18563476 0.29 ENSDART00000170841
cav1
caveolin 1
chr7_-_20758825 0.28 ENSDART00000156717
ENSDART00000182629
ENSDART00000179801
chd3
chromodomain helicase DNA binding protein 3
chr15_-_14884332 0.28 ENSDART00000165237
si:ch211-24o8.4
si:ch211-24o8.4
chr19_-_47527093 0.28 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
scg5
secretogranin V
chr18_+_30508729 0.28 ENSDART00000185140
cox4i1
cytochrome c oxidase subunit IV isoform 1
chr6_+_30689239 0.27 ENSDART00000065206
wdr78
WD repeat domain 78
chr9_+_29616854 0.26 ENSDART00000033902
ENSDART00000143493
phf11
PHD finger protein 11
chr12_+_18899396 0.26 ENSDART00000105858
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr16_-_41465542 0.25 ENSDART00000169116
ENSDART00000187446
cpne4a
copine IVa
chr7_+_12927944 0.25 ENSDART00000027329
fth1a
ferritin, heavy polypeptide 1a
chr14_-_7137808 0.25 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr15_-_34658057 0.25 ENSDART00000110964
bag6
BCL2 associated athanogene 6
chr19_+_22074468 0.25 ENSDART00000136294
ENSDART00000090476
atp9b
ATPase phospholipid transporting 9B
chr16_+_7242610 0.24 ENSDART00000081477
sri
sorcin
chr22_+_37631234 0.24 ENSDART00000007346
psmd1
proteasome 26S subunit, non-ATPase 1
chr10_+_39893439 0.24 ENSDART00000003435
smfn
small fragment nuclease
chr2_+_20802876 0.24 ENSDART00000142321
prg4a
proteoglycan 4a
chr4_-_14915268 0.23 ENSDART00000067040
si:dkey-180p18.9
si:dkey-180p18.9
chr11_-_41220794 0.23 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr18_-_49318823 0.23 ENSDART00000098419
sb:cb81
sb:cb81
chr7_-_73851280 0.23 ENSDART00000190053
FP236812.3

chr18_+_16192083 0.23 ENSDART00000133042
lrriq1
leucine-rich repeats and IQ motif containing 1
chr1_-_46875493 0.23 ENSDART00000115081
agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr24_-_21819010 0.23 ENSDART00000091096
CR352265.1

chr15_-_21877726 0.22 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr21_-_19314618 0.22 ENSDART00000188744
gpat3
glycerol-3-phosphate acyltransferase 3
chr11_+_1608348 0.21 ENSDART00000162438
si:dkey-40c23.3
si:dkey-40c23.3
chr15_-_1822548 0.21 ENSDART00000082026
ENSDART00000180230
mmp28
matrix metallopeptidase 28
chr14_-_5678457 0.20 ENSDART00000012116
tlx2
T cell leukemia homeobox 2
chr5_-_10239079 0.20 ENSDART00000132739
si:ch73-42k18.1
si:ch73-42k18.1
chr11_-_22371105 0.20 ENSDART00000146873
tmem183a
transmembrane protein 183A
chr12_+_28799988 0.19 ENSDART00000022724
pnpo
pyridoxamine 5'-phosphate oxidase
chr12_+_47698356 0.19 ENSDART00000112010
lzts2b
leucine zipper, putative tumor suppressor 2b
chr25_+_14165447 0.19 ENSDART00000145387
shank2
SH3 and multiple ankyrin repeat domains 2
chr22_-_19552796 0.19 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
si:dkey-78l4.14
chr22_+_37631034 0.19 ENSDART00000159016
ENSDART00000193346
psmd1
proteasome 26S subunit, non-ATPase 1
chr6_+_18569453 0.18 ENSDART00000171338
rhot1b
ras homolog family member T1
chr23_-_44207349 0.18 ENSDART00000186276
zgc:158659
zgc:158659
chr8_+_20951590 0.18 ENSDART00000138728
si:dkeyp-82a1.1
si:dkeyp-82a1.1
chr2_-_1364678 0.17 ENSDART00000011919
ENSDART00000164674
ss18
synovial sarcoma translocation, chromosome 18 (H. sapiens)
chr5_+_66433287 0.17 ENSDART00000170757
kntc1
kinetochore associated 1
chr20_+_10544100 0.17 ENSDART00000113927
serpina1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_+_17069577 0.17 ENSDART00000131847
si:dkey-190g11.3
si:dkey-190g11.3
chr1_-_8192418 0.17 ENSDART00000136654
grapb
GRB2-related adaptor protein b
chr13_+_45709380 0.17 ENSDART00000192862
si:ch211-62a1.3
si:ch211-62a1.3
chr17_+_13088800 0.16 ENSDART00000149779
gemin2
gem (nuclear organelle) associated protein 2
chr23_-_16485190 0.16 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr1_+_8442071 0.16 ENSDART00000143547
myo15ab
myosin XVAb
chr23_+_4689626 0.16 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr22_+_16555939 0.15 ENSDART00000012604
pdzk1ip1
PDZK1 interacting protein 1
chr16_+_3004422 0.15 ENSDART00000189969
CABZ01043952.1

chr3_+_25825043 0.15 ENSDART00000153749
pik3r6b
phosphoinositide-3-kinase, regulatory subunit 6b
chr23_+_2760573 0.15 ENSDART00000129719
top1
DNA topoisomerase I
chr5_+_67268110 0.15 ENSDART00000148116
si:ch211-110p13.9
si:ch211-110p13.9
chr25_+_18965430 0.15 ENSDART00000169742
tdg.1
thymine DNA glycosylase, tandem duplicate 1
chr4_-_14315855 0.15 ENSDART00000133325
nell2b
neural EGFL like 2b
chr24_+_26134209 0.15 ENSDART00000038824
tmtopsb
teleost multiple tissue opsin b
chr9_-_52490579 0.15 ENSDART00000161667
smarcal1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr24_+_38301080 0.14 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr20_+_18551657 0.14 ENSDART00000147001
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr21_-_22689805 0.14 ENSDART00000157560
ENSDART00000110792
gig2e
grass carp reovirus (GCRV)-induced gene 2e
chr8_-_44004135 0.14 ENSDART00000136269
rimbp2
RIMS binding protein 2
chr25_-_24248000 0.14 ENSDART00000073527
spty2d1
SPT2 chromatin protein domain containing 1
chr11_+_36665359 0.14 ENSDART00000166144
si:ch211-11c3.9
si:ch211-11c3.9
chr6_-_43882696 0.13 ENSDART00000064938
foxp1b
forkhead box P1b
chr4_-_56898328 0.13 ENSDART00000169189
si:dkey-269o24.6
si:dkey-269o24.6
chr15_-_28082310 0.13 ENSDART00000152620
dhrs13a.3
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr4_+_16787488 0.13 ENSDART00000143006
golt1ba
golgi transport 1Ba
chr23_+_40460333 0.13 ENSDART00000184658
soga3b
SOGA family member 3b
chr15_-_30816370 0.13 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
msi2b
musashi RNA-binding protein 2b
chr21_+_9689103 0.12 ENSDART00000165132
mapk10
mitogen-activated protein kinase 10
chr15_-_20400423 0.12 ENSDART00000081290
ENSDART00000156813
ENSDART00000192427
rnaset2l
ribonuclease T2, like
chr2_+_31614533 0.12 ENSDART00000111038
ENSDART00000181311
si:ch211-106h4.6
si:ch211-106h4.6
chr7_-_38698583 0.12 ENSDART00000173900
ENSDART00000126737
cd59
CD59 molecule (CD59 blood group)
chr7_+_19495379 0.12 ENSDART00000180514
si:ch211-212k18.8
si:ch211-212k18.8
chr16_-_15988320 0.12 ENSDART00000160883
CABZ01060453.1

chr1_+_23784905 0.12 ENSDART00000171951
ENSDART00000188521
ENSDART00000183029
ENSDART00000187183
slit2
slit homolog 2 (Drosophila)
chr10_-_44355534 0.12 ENSDART00000160231
sbno1
strawberry notch homolog 1 (Drosophila)
chr18_-_33979693 0.11 ENSDART00000021215
si:ch211-203b20.7
si:ch211-203b20.7
chr16_-_13004166 0.11 ENSDART00000133735
cacng7b
calcium channel, voltage-dependent, gamma subunit 7b
chr10_+_40598791 0.11 ENSDART00000131895
taar17a
trace amine associated receptor 17a
chr6_-_27891961 0.11 ENSDART00000155116
im:7152348
im:7152348
chr17_+_32343121 0.11 ENSDART00000156051
dhx32b
DEAH (Asp-Glu-Ala-His) box polypeptide 32b
chr17_+_25444323 0.11 ENSDART00000030691
clic4
chloride intracellular channel 4
chr3_-_39198113 0.11 ENSDART00000102690
RETSAT
zgc:154169
chr5_+_36611128 0.11 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr13_-_7567707 0.11 ENSDART00000190296
ENSDART00000180348
pitx3
paired-like homeodomain 3
chr15_+_42397125 0.10 ENSDART00000169751
tiam1b
T cell lymphoma invasion and metastasis 1b
chr23_-_35491587 0.10 ENSDART00000153794
fam110c
family with sequence similarity 110, member C
chr14_-_413273 0.10 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr13_-_49585385 0.10 ENSDART00000165868
tomm20a
translocase of outer mitochondrial membrane 20
chr25_-_18953322 0.10 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr22_+_18166660 0.10 ENSDART00000105432
borcs8
BLOC-1 related complex subunit 8
chr25_-_13839743 0.09 ENSDART00000158780
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr4_-_43388943 0.09 ENSDART00000150796
si:dkey-29j8.2
si:dkey-29j8.2
chr15_+_23799461 0.09 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr10_+_40578332 0.09 ENSDART00000146155
si:ch211-238p8.18
si:ch211-238p8.18
chr6_-_39270851 0.09 ENSDART00000148839
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr20_-_29633507 0.09 ENSDART00000040292
cpsf3
cleavage and polyadenylation specific factor 3
chr5_-_30491172 0.09 ENSDART00000138464
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr5_-_66768121 0.09 ENSDART00000141095
FERMT3 (1 of many)
im:7154036
chr16_-_55028740 0.08 ENSDART00000156368
ENSDART00000161704
zgc:114181
zgc:114181
chr7_+_48761875 0.08 ENSDART00000003690
acana
aggrecan a
chr6_+_41191482 0.08 ENSDART00000000877
opn1mw3
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr1_-_999556 0.08 ENSDART00000170884
ENSDART00000172235
gart
phosphoribosylglycinamide formyltransferase
chr23_-_21453614 0.08 ENSDART00000079274
her4.1
hairy-related 4, tandem duplicate 1
chr11_-_41996957 0.08 ENSDART00000055706
her15.2
hairy and enhancer of split-related 15, tandem duplicate 2
chr11_-_27874116 0.08 ENSDART00000180579
eif4g3a
eukaryotic translation initiation factor 4 gamma, 3a
chr2_+_20793982 0.08 ENSDART00000014785
prg4a
proteoglycan 4a
chr7_+_20017211 0.08 ENSDART00000100808
bcl6b
B-cell CLL/lymphoma 6, member B
chr23_+_23182037 0.08 ENSDART00000137353
klhl17
kelch-like family member 17
chr7_-_17570923 0.07 ENSDART00000188476
ENSDART00000080624
nitr5
novel immune-type receptor 5
chr25_+_3318192 0.07 ENSDART00000146154
slc25a3b
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3b
chr18_-_30020879 0.07 ENSDART00000162086
si:ch211-220f16.2
si:ch211-220f16.2
chr19_+_7757682 0.07 ENSDART00000092138
ENSDART00000092112
ubap2l
ubiquitin associated protein 2-like
chr7_-_9873652 0.07 ENSDART00000006343
asb7
ankyrin repeat and SOCS box containing 7
chr7_-_24699985 0.07 ENSDART00000052802
calb2b
calbindin 2b
chr1_+_50987535 0.07 ENSDART00000140657
mdh1aa
malate dehydrogenase 1Aa, NAD (soluble)
chr21_-_13123176 0.07 ENSDART00000144866
ENSDART00000024616
fam219aa
family with sequence similarity 219, member Aa
chr15_-_17813680 0.07 ENSDART00000158556
CT573342.2

chr10_+_39952995 0.07 ENSDART00000183077
BX927333.1

chr10_-_41980797 0.07 ENSDART00000076575
rhof
ras homolog family member F
chr16_-_17578503 0.07 ENSDART00000122212
casp2
caspase 2, apoptosis-related cysteine peptidase
chr14_+_4807207 0.07 ENSDART00000167145
ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr11_+_10975012 0.06 ENSDART00000192872
itgb6
integrin, beta 6
chr2_+_37815687 0.06 ENSDART00000166352
sdr39u1
short chain dehydrogenase/reductase family 39U, member 1
chr23_+_404975 0.06 ENSDART00000181336
CU929146.1

chr16_-_17541890 0.06 ENSDART00000131328
clcn1b
chloride channel, voltage-sensitive 1b
chr5_+_59392183 0.06 ENSDART00000082983
ENSDART00000180882
clip2
CAP-GLY domain containing linker protein 2
chr13_+_30692669 0.06 ENSDART00000187818
CR762483.1

chr4_-_815871 0.06 ENSDART00000067455
dpysl5b
dihydropyrimidinase-like 5b
chr20_+_15600167 0.06 ENSDART00000171991
faslg
Fas ligand (TNF superfamily, member 6)
chr25_+_30074947 0.06 ENSDART00000154849
si:ch211-147k10.5
si:ch211-147k10.5
chr12_+_18681477 0.06 ENSDART00000127981
ENSDART00000143979
rgs9b
regulator of G protein signaling 9b
chr4_+_28364237 0.06 ENSDART00000187933
ENSDART00000150424
si:ch73-263o4.4
si:ch73-263o4.4
chr7_+_5910467 0.06 ENSDART00000173232
si:ch211-113a14.22
si:ch211-113a14.22
chr6_-_8480815 0.06 ENSDART00000162300
rasal3
RAS protein activator like 3
chr4_-_18202291 0.06 ENSDART00000169704
anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr22_-_24757785 0.06 ENSDART00000078225
vtg5
vitellogenin 5
chr23_-_29553430 0.05 ENSDART00000157773
ENSDART00000126384
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr8_+_28065803 0.05 ENSDART00000178481
kcnd3
potassium voltage-gated channel, Shal-related subfamily, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxd4a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0051026 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:1990592 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.2 GO:0042822 water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.3 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.2 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.3 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.3 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.3 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.7 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.1 GO:0071435 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.0 0.1 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.7 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.3 GO:0042744 oxygen transport(GO:0015671) hydrogen peroxide catabolic process(GO:0042744)
0.0 0.7 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.4 GO:0043073 germ cell nucleus(GO:0043073)
0.1 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.2 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.3 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 1.1 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.6 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID FOXO PATHWAY FoxO family signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA