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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for ikzf1

Z-value: 1.03

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Transcription factors associated with ikzf1

Gene Symbol Gene ID Gene Info
ikzf1
ENSDARG00000013539 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ikzf1dr11_v1_chr13_-_15982707_15982707-0.791.1e-04Click!

Activity profile of ikzf1 motif

Sorted Z-values of ikzf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_1009831 4.09 ENSDART00000172414
fabp1b.2
fatty acid binding protein 1b, liver, tandem duplicate 2
chr25_+_30196039 3.43 ENSDART00000005299
hsd17b12a
hydroxysteroid (17-beta) dehydrogenase 12a
chr7_+_67699009 3.29 ENSDART00000192810
zgc:162592
zgc:162592
chr11_-_1550709 2.53 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr1_-_33645967 2.26 ENSDART00000192758
cldng
claudin g
chr21_+_13383413 2.20 ENSDART00000151345
zgc:113162
zgc:113162
chr10_-_25217347 2.20 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr23_-_45955177 2.15 ENSDART00000165963
ENSDART00000186649
ENSDART00000185773
LO017850.1

chr5_+_39099172 2.14 ENSDART00000006079
bmp2k
BMP2 inducible kinase
chr24_-_34680956 2.09 ENSDART00000171009
ctnna1
catenin (cadherin-associated protein), alpha 1
chr18_-_16953978 2.06 ENSDART00000100126
akip1
A kinase (PRKA) interacting protein 1
chr2_+_35603637 2.00 ENSDART00000147278
plk3
polo-like kinase 3 (Drosophila)
chr6_+_21005725 1.97 ENSDART00000041370
cx44.2
connexin 44.2
chr7_+_61764040 1.95 ENSDART00000056745
acox3
acyl-CoA oxidase 3, pristanoyl
chr7_+_39410180 1.87 ENSDART00000168641
CT030188.1

chr6_+_54680730 1.86 ENSDART00000074602
smpd2b
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr12_-_1034383 1.85 ENSDART00000152455
ENSDART00000152346
polr3e
polymerase (RNA) III (DNA directed) polypeptide E
chr7_+_39410393 1.85 ENSDART00000158561
ENSDART00000185173
CT030188.1

chr13_-_15929402 1.84 ENSDART00000090273
ttl
tubulin tyrosine ligase
chr24_-_26622423 1.83 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr13_-_24825691 1.66 ENSDART00000142745
slka
STE20-like kinase a
chr2_-_15324837 1.61 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr8_+_52442785 1.61 ENSDART00000189958
zgc:77112
zgc:77112
chr8_-_1730686 1.59 ENSDART00000183802
CABZ01065416.1

chr15_+_30126971 1.58 ENSDART00000100214
nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr7_-_59159253 1.57 ENSDART00000159285
haus6
HAUS augmin-like complex, subunit 6
chr3_+_27665160 1.56 ENSDART00000103660
clcn7
chloride channel 7
chr5_+_44805269 1.54 ENSDART00000136965
ctsla
cathepsin La
chr15_-_47193564 1.53 ENSDART00000172453
LSAMP
limbic system-associated membrane protein
chr5_+_9037650 1.52 ENSDART00000158226
si:ch211-155m12.1
si:ch211-155m12.1
chr7_+_67699178 1.51 ENSDART00000160086
zgc:162592
zgc:162592
chr21_+_13387965 1.49 ENSDART00000134347
zgc:113162
zgc:113162
chr5_-_54712159 1.47 ENSDART00000149207
ccnb1
cyclin B1
chr16_+_31511739 1.44 ENSDART00000049420
ndrg1b
N-myc downstream regulated 1b
chr11_+_11303458 1.44 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
si:dkey-23f9.4
chr19_-_27830818 1.42 ENSDART00000131767
papd7
PAP associated domain containing 7
chr20_-_13623882 1.42 ENSDART00000125218
ENSDART00000152499
sytl3
synaptotagmin-like 3
chr19_+_34230108 1.41 ENSDART00000141950
galnt12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr13_-_36525982 1.40 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr18_-_16907436 1.40 ENSDART00000146464
swap70b
switching B cell complex subunit SWAP70b
chr21_-_4849029 1.40 ENSDART00000168930
ENSDART00000151019
notch1a
notch 1a
chr1_+_40613297 1.39 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr17_+_6793001 1.32 ENSDART00000030773
foxo3a
forkhead box O3A
chr20_-_15161669 1.31 ENSDART00000080333
ENSDART00000063882
plpp6
phospholipid phosphatase 6
chr3_+_46762703 1.31 ENSDART00000133283
prkcsh
protein kinase C substrate 80K-H
chr9_-_11676491 1.28 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr17_+_33415319 1.28 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr17_+_2549503 1.28 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr16_+_33142734 1.23 ENSDART00000138244
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr20_+_42246948 1.22 ENSDART00000061135
gopc
golgi-associated PDZ and coiled-coil motif containing
chr21_-_34951265 1.21 ENSDART00000135222
lipia
lipase, member Ia
chr2_-_42558549 1.21 ENSDART00000025997
dip2cb
disco-interacting protein 2 homolog Cb
chr24_-_9989634 1.20 ENSDART00000115275
zgc:152652
zgc:152652
chr15_+_29025090 1.19 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr19_+_20201254 1.19 ENSDART00000010140
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr8_-_43716897 1.18 ENSDART00000163237
ep400
E1A binding protein p400
chr21_+_43172506 1.18 ENSDART00000121725
zcchc10
zinc finger, CCHC domain containing 10
chr20_-_48898560 1.18 ENSDART00000163071
xrn2
5'-3' exoribonuclease 2
chr17_+_33415542 1.16 ENSDART00000183169
snap23.1
synaptosomal-associated protein 23.1
chr10_-_44008241 1.14 ENSDART00000137686
acads
acyl-CoA dehydrogenase short chain
chr6_+_36821621 1.14 ENSDART00000104157
tmem45a
transmembrane protein 45a
chr1_-_43712120 1.13 ENSDART00000074600
SLC9B2
si:dkey-162b23.4
chr17_+_28102487 1.13 ENSDART00000131638
ENSDART00000076265
zgc:91908
zgc:91908
chr22_-_17671348 1.12 ENSDART00000137995
tjp3
tight junction protein 3
chr23_+_26026383 1.12 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_+_28492990 1.11 ENSDART00000160347
ENSDART00000187176
ENSDART00000088094
stag2b
stromal antigen 2b
chr7_+_25003313 1.10 ENSDART00000131935
naa40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr15_+_11693624 1.08 ENSDART00000193630
ENSDART00000161930
strn4
striatin, calmodulin binding protein 4
chr19_+_1658698 1.07 ENSDART00000158311
klhl7
kelch-like family member 7
chr6_+_1724889 1.06 ENSDART00000157415
acvr2ab
activin A receptor type 2Ab
chr23_+_43668756 1.05 ENSDART00000112598
otud4
OTU deubiquitinase 4
chr7_-_58098814 1.05 ENSDART00000147287
ENSDART00000043984
ank2b
ankyrin 2b, neuronal
chr17_-_25331439 1.04 ENSDART00000155422
ENSDART00000082324
zpcx
zona pellucida protein C
chr2_-_49031303 1.03 ENSDART00000143471
cdc34b
cell division cycle 34 homolog (S. cerevisiae) b
chr13_+_15816573 1.03 ENSDART00000137061
klc1a
kinesin light chain 1a
chr11_-_27953135 1.02 ENSDART00000168338
ece1
endothelin converting enzyme 1
chr8_+_14959587 1.02 ENSDART00000138548
ENSDART00000041697
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr19_+_20201593 1.01 ENSDART00000163026
igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr17_-_8592824 1.01 ENSDART00000127022
CU462878.1

chr8_-_39822917 1.00 ENSDART00000067843
zgc:162025
zgc:162025
chr6_+_2195625 1.00 ENSDART00000155659
acvr1bb
activin A receptor type 1Bb
chr17_+_38295847 0.99 ENSDART00000008532
mbip
MAP3K12 binding inhibitory protein 1
chr20_-_4049862 0.98 ENSDART00000158057
sprtn
SprT-like N-terminal domain
chr17_+_25187670 0.98 ENSDART00000190873
cln8
CLN8, transmembrane ER and ERGIC protein
chr17_-_6613458 0.96 ENSDART00000175024
si:ch211-189e2.3
si:ch211-189e2.3
chr5_-_23675222 0.96 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr3_+_17653784 0.94 ENSDART00000159984
ENSDART00000157682
ENSDART00000187937
kat2a
K(lysine) acetyltransferase 2A
chr17_-_24879003 0.94 ENSDART00000123147
zbtb8a
zinc finger and BTB domain containing 8A
chr24_-_31090948 0.94 ENSDART00000176799
hccsb
holocytochrome c synthase b
chr14_+_7048930 0.93 ENSDART00000109138
hbegfa
heparin-binding EGF-like growth factor a
chr2_+_243778 0.92 ENSDART00000182262
CABZ01085887.1

chr9_-_28255029 0.91 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr7_+_34549377 0.91 ENSDART00000191814
fhod1
formin homology 2 domain containing 1
chr17_-_30521043 0.90 ENSDART00000087111
itsn2b
intersectin 2b
chr21_-_25295087 0.90 ENSDART00000087910
ENSDART00000147860
st14b
suppression of tumorigenicity 14 (colon carcinoma) b
chr2_+_54844755 0.90 ENSDART00000170428
rnf126
ring finger protein 126
chr3_+_35005730 0.89 ENSDART00000029451
prkcbb
protein kinase C, beta b
chr25_-_6049339 0.89 ENSDART00000075184
snx1a
sorting nexin 1a
chr20_+_36806398 0.89 ENSDART00000153317
abracl
ABRA C-terminal like
chr2_-_42492445 0.88 ENSDART00000139929
esyt2a
extended synaptotagmin-like protein 2a
chr23_-_31967554 0.88 ENSDART00000183973
ormdl2
ORMDL sphingolipid biosynthesis regulator 2
chr9_-_34260214 0.88 ENSDART00000012385
me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr5_+_48666485 0.88 ENSDART00000158000
ENSDART00000031141
polr3g
polymerase (RNA) III (DNA directed) polypeptide G
chr5_+_39099380 0.87 ENSDART00000166657
bmp2k
BMP2 inducible kinase
chr2_-_5723786 0.87 ENSDART00000100924
cwc25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr20_-_31238313 0.87 ENSDART00000028471
hpcal1
hippocalcin-like 1
chr22_-_15704704 0.86 ENSDART00000017838
ENSDART00000130238
safb
scaffold attachment factor B
chr19_-_17864213 0.86 ENSDART00000151043
ints8
integrator complex subunit 8
chr6_-_30485009 0.85 ENSDART00000025698
zgc:153311
zgc:153311
chr14_+_20918701 0.84 ENSDART00000144736
ENSDART00000148204
zgc:66433
zgc:66433
chr11_-_11791718 0.84 ENSDART00000180476
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr8_+_20488322 0.84 ENSDART00000036630
zgc:101100
zgc:101100
chr2_+_23701613 0.84 ENSDART00000047073
oxsr1a
oxidative stress responsive 1a
chr11_-_26701611 0.82 ENSDART00000083010
acad9
acyl-CoA dehydrogenase family, member 9
chr20_-_15161502 0.82 ENSDART00000187072
plpp6
phospholipid phosphatase 6
chr9_+_21402863 0.80 ENSDART00000125357
cx30.3
connexin 30.3
chr16_-_22585289 0.80 ENSDART00000134239
ENSDART00000193959
ENSDART00000077998
si:dkey-238m4.3
cgna
si:dkey-238m4.3
cingulin a
chr12_-_13549538 0.79 ENSDART00000133895
ghdc
GH3 domain containing
chr16_-_31791165 0.79 ENSDART00000148389
chd4b
chromodomain helicase DNA binding protein 4b
chr7_+_62080456 0.78 ENSDART00000092580
rbpjb
recombination signal binding protein for immunoglobulin kappa J region b
chr20_-_53078607 0.77 ENSDART00000163494
ENSDART00000191730
CABZ01066813.1

chr6_-_12135741 0.77 ENSDART00000155090
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr17_-_25861787 0.76 ENSDART00000182503
BX000364.5

chr3_+_31925067 0.75 ENSDART00000127330
ENSDART00000055279
snrnp70
small nuclear ribonucleoprotein 70 (U1)
chr5_+_24087035 0.75 ENSDART00000183644
tp53
tumor protein p53
chr1_+_51066671 0.75 ENSDART00000064007
srd5a2a
steroid-5-alpha-reductase, alpha polypeptide 2a
chr7_+_24006875 0.75 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr6_+_19933763 0.75 ENSDART00000166192
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr5_-_26247215 0.74 ENSDART00000136806
erap1b
endoplasmic reticulum aminopeptidase 1b
chr6_-_41135215 0.73 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr17_+_25331576 0.73 ENSDART00000157309
tmem54a
transmembrane protein 54a
chr23_-_270847 0.72 ENSDART00000191867
anks1aa
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr9_+_38888025 0.72 ENSDART00000148306
map2
microtubule-associated protein 2
chr17_+_23462972 0.72 ENSDART00000112959
ENSDART00000192168
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr13_+_15580758 0.71 ENSDART00000087194
ENSDART00000013525
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr19_+_9050852 0.71 ENSDART00000151031
ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr8_-_15182232 0.71 ENSDART00000138855
bcar3
BCAR3, NSP family adaptor protein
chr5_+_61657702 0.71 ENSDART00000134387
ENSDART00000171248
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr22_+_4443689 0.69 ENSDART00000185490
ticam1
toll-like receptor adaptor molecule 1
chr3_+_50172452 0.68 ENSDART00000191224
epn3a
epsin 3a
chr9_-_25366541 0.68 ENSDART00000021672
epc2
enhancer of polycomb homolog 2 (Drosophila)
chr17_-_33416020 0.68 ENSDART00000140149
ccdc28a
coiled-coil domain containing 28A
chr6_+_41554794 0.67 ENSDART00000165424
srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr20_+_22799857 0.67 ENSDART00000058527
scfd2
sec1 family domain containing 2
chr7_+_54259657 0.67 ENSDART00000170174
pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr10_-_35177257 0.67 ENSDART00000077426
pom121
POM121 transmembrane nucleoporin
chr21_+_39100289 0.67 ENSDART00000075958
slc13a2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_-_11357851 0.67 ENSDART00000153915
si:ch211-185a18.2
si:ch211-185a18.2
chr5_-_23705828 0.67 ENSDART00000189419
gbgt1l1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr6_+_58289335 0.66 ENSDART00000177399
ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr9_+_55857193 0.65 ENSDART00000160980
sept10
septin 10
chr6_-_11792152 0.64 ENSDART00000183403
march7
membrane-associated ring finger (C3HC4) 7
chr6_-_54433995 0.64 ENSDART00000017230
snrpc
small nuclear ribonucleoprotein polypeptide C
chr8_-_23776399 0.64 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr8_-_50888806 0.63 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr2_+_5300405 0.63 ENSDART00000019925
GNB4
G protein subunit beta 4
chr23_+_1661743 0.63 ENSDART00000044776
stxbp3
syntaxin binding protein 3
chr13_+_38302665 0.62 ENSDART00000145777
adgrb3
adhesion G protein-coupled receptor B3
chr17_-_14774117 0.62 ENSDART00000080401
si:ch211-266o15.1
si:ch211-266o15.1
chr23_+_33963619 0.61 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr15_-_1001177 0.60 ENSDART00000160730
zgc:162936
zgc:162936
chr13_-_31389661 0.60 ENSDART00000134630
zdhhc16a
zinc finger, DHHC-type containing 16a
chr6_-_10740365 0.60 ENSDART00000150942
sp3b
Sp3b transcription factor
chr20_+_22799641 0.60 ENSDART00000131132
scfd2
sec1 family domain containing 2
chr15_-_1835189 0.60 ENSDART00000154369
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_+_58377395 0.60 ENSDART00000193511
vapal
VAMP (vesicle-associated membrane protein)-associated protein A, like
chr6_-_10725847 0.59 ENSDART00000184567
sp3b
Sp3b transcription factor
chr2_-_22659450 0.59 ENSDART00000115025
thap4
THAP domain containing 4
chr6_-_16456093 0.59 ENSDART00000083305
ENSDART00000181640
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr18_+_7543347 0.59 ENSDART00000103467
arf5
ADP-ribosylation factor 5
chr2_-_30784502 0.59 ENSDART00000056735
rgs20
regulator of G protein signaling 20
chr3_+_17806213 0.59 ENSDART00000055890
znf385c
zinc finger protein 385C
chr5_+_20319519 0.59 ENSDART00000004217
coro1ca
coronin, actin binding protein, 1Ca
chr16_-_13680692 0.58 ENSDART00000047452
ube2s
ubiquitin-conjugating enzyme E2S
chr15_-_20709289 0.57 ENSDART00000136767
tpst1
tyrosylprotein sulfotransferase 1
chr25_-_31763897 0.57 ENSDART00000041740
ubl7a
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr7_+_36898622 0.57 ENSDART00000190773
tox3
TOX high mobility group box family member 3
chr10_+_35347993 0.57 ENSDART00000131350
si:dkey-259j3.5
si:dkey-259j3.5
chr5_+_26686639 0.57 ENSDART00000079064
tango2
transport and golgi organization 2 homolog (Drosophila)
chr12_+_23991276 0.56 ENSDART00000153136
psme4b
proteasome activator subunit 4b
chr12_+_28955766 0.56 ENSDART00000123417
ENSDART00000139347
znf668
zinc finger protein 668
chr10_-_38468847 0.55 ENSDART00000133914
gdpd5a
glycerophosphodiester phosphodiesterase domain containing 5a
chr6_-_53204808 0.55 ENSDART00000160955
slc38a3b
solute carrier family 38, member 3b
chr15_-_47895200 0.55 ENSDART00000027060
DMWD
zmp:0000000529
chr5_+_32817688 0.55 ENSDART00000139472
crata
carnitine O-acetyltransferase a
chr7_+_31130667 0.53 ENSDART00000173937
tjp1a
tight junction protein 1a
chr18_+_35861930 0.53 ENSDART00000185223
ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr23_-_25135046 0.53 ENSDART00000184844
ENSDART00000103989
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr12_+_27285994 0.53 ENSDART00000087204
dusp3a
dual specificity phosphatase 3a
chr2_-_21847935 0.52 ENSDART00000003940
rab2a
RAB2A, member RAS oncogene family
chr9_+_6997861 0.52 ENSDART00000190491
inpp4aa
inositol polyphosphate-4-phosphatase type I Aa
chr22_-_14255659 0.52 ENSDART00000167088
si:ch211-246m6.5
si:ch211-246m6.5
chr9_+_38458193 0.52 ENSDART00000008053
mcm3ap
minichromosome maintenance complex component 3 associated protein
chr20_+_54336137 0.52 ENSDART00000113792
cipcb
CLOCK-interacting pacemaker b
chr4_-_9822519 0.51 ENSDART00000131357
parp12b
poly (ADP-ribose) polymerase family, member 12b
chr2_+_23062085 0.51 ENSDART00000153745
csnk1g2a
casein kinase 1, gamma 2a
chr2_-_33645411 0.51 ENSDART00000114663
b4galt2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr25_+_33063762 0.51 ENSDART00000189974
tln2b
talin 2b
chr3_-_38777553 0.49 ENSDART00000193045
znf281a
zinc finger protein 281a
chr15_-_2857961 0.49 ENSDART00000033263
ankrd49
ankyrin repeat domain 49

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.5 1.4 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.5 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 3.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.3 2.0 GO:0044819 mitotic G1/S transition checkpoint(GO:0044819)
0.3 1.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.3 1.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.3 1.0 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 0.8 GO:1901216 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 0.7 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.2 1.4 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 0.7 GO:0032816 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.2 0.9 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 1.0 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 1.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 1.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.2 0.9 GO:0018063 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 0.9 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 3.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 1.0 GO:0097065 anterior head development(GO:0097065)
0.2 1.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.2 1.5 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.2 0.5 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.2 1.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.4 GO:1901004 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.5 GO:0006867 asparagine transport(GO:0006867)
0.1 2.1 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.6 GO:0016322 neuron remodeling(GO:0016322)
0.1 4.8 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.5 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 1.1 GO:0030104 water homeostasis(GO:0030104)
0.1 0.5 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.4 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.1 0.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 1.1 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.9 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of protein tyrosine kinase activity(GO:0061098) positive regulation of receptor activity(GO:2000273)
0.1 0.6 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.1 0.6 GO:0045117 azole transport(GO:0045117)
0.1 0.6 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.6 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 1.9 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.1 2.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.9 GO:1903010 regulation of bone development(GO:1903010)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:0034627 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.1 1.6 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.6 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 1.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.0 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.5 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.6 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 1.0 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.4 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.2 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.1 0.6 GO:0014028 notochord formation(GO:0014028)
0.1 0.3 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.5 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 2.2 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.0 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.7 GO:0006405 RNA export from nucleus(GO:0006405)
0.0 1.9 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.5 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.5 GO:0046620 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.0 0.4 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 3.0 GO:0051028 mRNA transport(GO:0051028)
0.0 1.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.5 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.9 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 1.3 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.3 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0003403 optic vesicle formation(GO:0003403)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.7 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0061511 centriole elongation(GO:0061511)
0.0 1.1 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 1.1 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.4 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.8 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.3 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.6 GO:0001894 tissue homeostasis(GO:0001894)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 1.0 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.9 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:0009648 photoperiodism(GO:0009648)
0.0 0.4 GO:0048264 positive regulation of BMP signaling pathway(GO:0030513) determination of ventral identity(GO:0048264)
0.0 0.2 GO:0051402 neuron apoptotic process(GO:0051402)
0.0 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.1 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.5 1.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.3 1.3 GO:0017177 glucosidase II complex(GO:0017177)
0.3 1.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 1.4 GO:0031415 NatA complex(GO:0031415)
0.2 0.7 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2 0.9 GO:0035339 SPOTS complex(GO:0035339)
0.2 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.2 1.6 GO:0042788 polysomal ribosome(GO:0042788)
0.2 2.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 2.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 2.1 GO:0030057 desmosome(GO:0030057)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 1.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0016586 RSC complex(GO:0016586)
0.1 0.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 1.6 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.0 GO:0030315 T-tubule(GO:0030315)
0.1 1.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.4 GO:0089701 U2AF(GO:0089701)
0.0 1.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 4.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.4 GO:0030118 clathrin coat(GO:0030118)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.4 GO:0030141 secretory granule(GO:0030141)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.8 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0071565 nBAF complex(GO:0071565)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.8 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.5 2.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.4 3.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.4 6.1 GO:0005504 fatty acid binding(GO:0005504)
0.3 1.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.3 1.1 GO:0043998 H2A histone acetyltransferase activity(GO:0043998)
0.3 0.8 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 1.1 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.3 3.0 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 0.9 GO:0004408 holocytochrome-c synthase activity(GO:0004408)
0.2 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.4 GO:0030619 U1 snRNA binding(GO:0030619)
0.2 1.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 1.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.6 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 2.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.5 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 1.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.9 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.4 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.5 GO:0070883 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.1 1.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 1.0 GO:0097001 sphingolipid binding(GO:0046625) ceramide binding(GO:0097001)
0.1 1.6 GO:2001069 glycogen binding(GO:2001069)
0.1 0.5 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.0 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 1.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 1.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.3 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.6 GO:0016504 peptidase activator activity(GO:0016504)
0.1 1.4 GO:0005112 Notch binding(GO:0005112)
0.1 1.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 1.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 4.4 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0030882 lipid antigen binding(GO:0030882)
0.0 1.9 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.8 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 2.2 GO:0030276 clathrin binding(GO:0030276)
0.0 2.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0 0.6 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.5 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 9.8 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 3.9 PID P73PATHWAY p73 transcription factor network
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 1.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.5 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 0.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 0.8 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.7 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane