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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for ikzf2

Z-value: 1.11

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Transcription factors associated with ikzf2

Gene Symbol Gene ID Gene Info
ikzf2
ENSDARG00000069111 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2dr11_v1_chr9_-_40073255_400732550.419.4e-02Click!

Activity profile of ikzf2 motif

Sorted Z-values of ikzf2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_38626926 2.46 ENSDART00000190339
atp10a
ATPase phospholipid transporting 10A
chr6_+_38626684 2.25 ENSDART00000086533
atp10a
ATPase phospholipid transporting 10A
chr19_+_41479990 2.15 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr14_-_21618005 2.00 ENSDART00000043162
reep2
receptor accessory protein 2
chr14_-_34605607 1.96 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr17_+_32531854 1.95 ENSDART00000123399
gcfc2
GC-rich sequence DNA-binding factor 2
chr16_-_38333976 1.81 ENSDART00000031895
cdc42se1
CDC42 small effector 1
chr3_-_15470944 1.79 ENSDART00000185302
spns1
spinster homolog 1 (Drosophila)
chr14_-_46198373 1.78 ENSDART00000031640
ENSDART00000132966
zgc:113425
zgc:113425
chr4_+_9279784 1.73 ENSDART00000014897
srgap1b
SLIT-ROBO Rho GTPase activating protein 1b
chr3_+_30921246 1.70 ENSDART00000076850
cldni
claudin i
chr14_-_34605804 1.69 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr13_-_21672131 1.67 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr3_-_25055795 1.61 ENSDART00000156459
ep300b
E1A binding protein p300 b
chr20_-_44090624 1.61 ENSDART00000048978
ENSDART00000082283
ENSDART00000082276
runx2b
runt-related transcription factor 2b
chr5_-_28968964 1.58 ENSDART00000184936
ENSDART00000016628
fam129bb
family with sequence similarity 129, member Bb
chr19_-_18136410 1.56 ENSDART00000012352
cbx3a
chromobox homolog 3a (HP1 gamma homolog, Drosophila)
chr20_+_46040666 1.53 ENSDART00000060744
si:dkey-7c18.24
si:dkey-7c18.24
chr1_-_59169815 1.47 ENSDART00000100163
wu:fk65c09
wu:fk65c09
chr15_-_17024779 1.45 ENSDART00000154719
hip1
huntingtin interacting protein 1
chr19_+_27859546 1.43 ENSDART00000161908
nsun2
NOP2/Sun RNA methyltransferase family, member 2
chr12_+_33403694 1.41 ENSDART00000124083
fasn
fatty acid synthase
chr17_-_8592824 1.40 ENSDART00000127022
CU462878.1

chr16_-_17345377 1.39 ENSDART00000143056
zyx
zyxin
chr23_+_27782071 1.38 ENSDART00000131379
kmt2d
lysine (K)-specific methyltransferase 2D
chr10_+_33573838 1.38 ENSDART00000051197
ENSDART00000130093
c10h21orf59
c10h21orf59 homolog (H. sapiens)
chr21_-_19918286 1.34 ENSDART00000180816
ppp1r3b
protein phosphatase 1, regulatory subunit 3B
chr14_-_32876280 1.33 ENSDART00000173168
si:rp71-46j2.7
si:rp71-46j2.7
chr23_+_40133136 1.29 ENSDART00000157616
gpsm2l
G protein signaling modulator 2, like
chr25_-_18948816 1.28 ENSDART00000091549
nt5dc3
5'-nucleotidase domain containing 3
chr12_+_27232173 1.27 ENSDART00000193714
tmem106a
transmembrane protein 106A
chr24_-_26622423 1.24 ENSDART00000182044
tnikb
TRAF2 and NCK interacting kinase b
chr1_+_14454663 1.23 ENSDART00000005067
rbpja
recombination signal binding protein for immunoglobulin kappa J region a
chr8_-_22538588 1.23 ENSDART00000144041
csde1
cold shock domain containing E1, RNA-binding
chr5_-_50084310 1.21 ENSDART00000074599
ENSDART00000189970
fam172a
family with sequence similarity 172, member A
chr6_+_28208973 1.21 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr8_-_22539113 1.21 ENSDART00000183297
ENSDART00000185981
csde1
cold shock domain containing E1, RNA-binding
chr12_+_17603528 1.20 ENSDART00000111565
pms2
PMS1 homolog 2, mismatch repair system component
chr3_+_26245731 1.20 ENSDART00000103734
atad5a
ATPase family, AAA domain containing 5a
chr10_+_36662640 1.18 ENSDART00000063359
ucp2
uncoupling protein 2
chr8_+_47683539 1.17 ENSDART00000190701
dpp9
dipeptidyl-peptidase 9
chr3_-_36127234 1.17 ENSDART00000130917
coil
coilin p80
chr12_+_16953415 1.16 ENSDART00000020824
pank1b
pantothenate kinase 1b
chr3_+_35498119 1.16 ENSDART00000178963
tnrc6a
trinucleotide repeat containing 6a
chr11_-_21404358 1.13 ENSDART00000129062
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr5_-_31772559 1.12 ENSDART00000183879
fam102ab
family with sequence similarity 102, member Ab
chr19_-_47832853 1.11 ENSDART00000170988
ago4
argonaute RISC catalytic component 4
chr6_-_10034145 1.10 ENSDART00000185999
nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr22_-_17653143 1.10 ENSDART00000089171
hmha1b
histocompatibility (minor) HA-1 b
chr1_+_51391082 1.09 ENSDART00000063936
atg4da
autophagy related 4D, cysteine peptidase a
chr8_+_21254192 1.07 ENSDART00000167718
itpr3
inositol 1,4,5-trisphosphate receptor, type 3
chr6_+_38896158 1.05 ENSDART00000029930
ENSDART00000131347
slc48a1b
solute carrier family 48 (heme transporter), member 1b
chr13_+_15580758 1.05 ENSDART00000087194
ENSDART00000013525
mark3a
MAP/microtubule affinity-regulating kinase 3a
chr18_+_11858397 1.03 ENSDART00000133762
tmtc2b
transmembrane and tetratricopeptide repeat containing 2b
chr1_+_16548733 1.03 ENSDART00000048855
mtus1b
microtubule associated tumor suppressor 1b
chr8_+_47683352 1.03 ENSDART00000187320
ENSDART00000192605
dpp9
dipeptidyl-peptidase 9
chr8_-_7232413 1.02 ENSDART00000092426
grip2a
glutamate receptor interacting protein 2a
chr1_+_35494837 1.02 ENSDART00000140724
gab1
GRB2-associated binding protein 1
chr1_+_35495368 1.01 ENSDART00000053806
gab1
GRB2-associated binding protein 1
chr19_+_24324967 1.01 ENSDART00000090081
sema4ab
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ab
chr20_+_26943072 1.01 ENSDART00000153215
cdca4
cell division cycle associated 4
chr21_+_31253048 1.01 ENSDART00000178521
ENSDART00000132317
ENSDART00000040190
asl
argininosuccinate lyase
chr18_-_12295092 1.00 ENSDART00000033248
fam107b
family with sequence similarity 107, member B
chr23_-_26227805 1.00 ENSDART00000158082
BX927204.1

chr19_+_42071814 1.00 ENSDART00000166422
ENSDART00000191058
nfyc
nuclear transcription factor Y, gamma
chr25_-_12906872 1.00 ENSDART00000165156
ENSDART00000167449
sept15
septin 15
chr3_-_34528306 0.97 ENSDART00000023039
sept9a
septin 9a
chr6_+_23809163 0.96 ENSDART00000170402
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr23_+_40139765 0.96 ENSDART00000185376
gpsm2l
G protein signaling modulator 2, like
chr14_-_24277805 0.95 ENSDART00000054243
dpf2l
D4, zinc and double PHD fingers family 2, like
chr20_-_14718801 0.95 ENSDART00000137605
suco
SUN domain containing ossification factor
chr10_+_7703251 0.94 ENSDART00000165134
ggcx
gamma-glutamyl carboxylase
chr3_+_53156813 0.93 ENSDART00000114343
brd4
bromodomain containing 4
chr11_-_21404044 0.93 ENSDART00000080116
ikbke
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr4_-_4250317 0.92 ENSDART00000103316
cd9b
CD9 molecule b
chr7_-_30553588 0.91 ENSDART00000139546
sltm
SAFB-like, transcription modulator
chr22_-_155627 0.91 ENSDART00000110807
si:ch1073-335m2.2
si:ch1073-335m2.2
chr1_+_54737353 0.91 ENSDART00000130675
ENSDART00000162075
pi4k2a
phosphatidylinositol 4-kinase type 2 alpha
chr5_-_65158203 0.91 ENSDART00000171656
sh2d3cb
SH2 domain containing 3Cb
chr3_+_28576173 0.89 ENSDART00000151189
sept12
septin 12
chr17_+_19626479 0.89 ENSDART00000044993
ENSDART00000131863
rgs7a
regulator of G protein signaling 7a
chr25_-_17910714 0.89 ENSDART00000191586
arntl1a
aryl hydrocarbon receptor nuclear translocator-like 1a
chr18_-_13056801 0.89 ENSDART00000088908
srgap1a
SLIT-ROBO Rho GTPase activating protein 1a
chr23_-_270847 0.88 ENSDART00000191867
anks1aa
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr2_+_22416275 0.87 ENSDART00000185179
ENSDART00000172715
pkn2
protein kinase N2
chr11_-_6868287 0.87 ENSDART00000037824
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr6_-_39518489 0.87 ENSDART00000185446
atf1
activating transcription factor 1
chr15_+_23657051 0.86 ENSDART00000078336
klc3
kinesin light chain 3
chr4_-_4261673 0.86 ENSDART00000150694
cd9b
CD9 molecule b
chr5_+_65086856 0.86 ENSDART00000169209
ENSDART00000162409
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr9_+_44391254 0.86 ENSDART00000148826
ssfa2
sperm specific antigen 2
chr4_-_7876005 0.85 ENSDART00000109252
nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr23_+_1181248 0.85 ENSDART00000170942
utrn
utrophin
chr17_-_15528597 0.83 ENSDART00000150232
fyna
FYN proto-oncogene, Src family tyrosine kinase a
chr19_+_46222918 0.83 ENSDART00000158703
vps28
vacuolar protein sorting 28 (yeast)
chr11_-_6868474 0.81 ENSDART00000168372
lsm4
LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
chr11_-_36046458 0.81 ENSDART00000061520
brk1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr13_+_34690158 0.79 ENSDART00000182978
tasp1
taspase, threonine aspartase, 1
chr22_-_3182965 0.78 ENSDART00000158009
lonp1
lon peptidase 1, mitochondrial
chr19_+_46222428 0.78 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr23_-_18668836 0.77 ENSDART00000138792
ENSDART00000051182
arhgap4b
Rho GTPase activating protein 4b
chr5_-_13766651 0.77 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr4_+_13909398 0.77 ENSDART00000187959
ENSDART00000184926
pphln1
periphilin 1
chr3_-_1263047 0.77 ENSDART00000184388
tcf20
transcription factor 20
chr21_+_37513058 0.76 ENSDART00000141096
amot
angiomotin
chr21_+_25120546 0.76 ENSDART00000149507
ddx10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr25_-_29074064 0.74 ENSDART00000165603
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr3_+_26244353 0.73 ENSDART00000103733
atad5a
ATPase family, AAA domain containing 5a
chr9_-_28939796 0.73 ENSDART00000101269
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr2_-_21819421 0.73 ENSDART00000121586
chd7
chromodomain helicase DNA binding protein 7
chr14_-_26498196 0.73 ENSDART00000054175
ENSDART00000145625
ENSDART00000183347
ENSDART00000191084
ENSDART00000191143
smad5
SMAD family member 5
chr15_+_29408886 0.72 ENSDART00000184581
ENSDART00000184478
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr9_-_12659140 0.72 ENSDART00000058565
pttg1ipb
PTTG1 interacting protein b
chr20_-_18789543 0.72 ENSDART00000182240
ccm2
cerebral cavernous malformation 2
chr4_-_18416566 0.71 ENSDART00000033717
cradd
CASP2 and RIPK1 domain containing adaptor with death domain
chr3_-_48603471 0.70 ENSDART00000189027
ndel1b
nudE neurodevelopment protein 1-like 1b
chr19_-_20403507 0.69 ENSDART00000052603
ENSDART00000137590
dazl
deleted in azoospermia-like
chr2_-_52550135 0.69 ENSDART00000044411
gna11b
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr6_-_47246948 0.69 ENSDART00000162435
grm4
glutamate receptor, metabotropic 4
chr3_-_60856157 0.69 ENSDART00000053502
CABZ01087513.1

chr22_+_15720381 0.68 ENSDART00000128149
fam32a
family with sequence similarity 32, member A
chr15_-_33807758 0.68 ENSDART00000158445
pds5b
PDS5 cohesin associated factor B
chr4_-_11053543 0.68 ENSDART00000067262
mettl25
methyltransferase like 25
chr20_-_43750771 0.67 ENSDART00000100605
ttc32
tetratricopeptide repeat domain 32
chr9_-_55946377 0.67 ENSDART00000161536
ENSDART00000169432
SH3RF3
si:ch211-124n19.2
chr21_-_30166097 0.67 ENSDART00000130676
hbegfb
heparin-binding EGF-like growth factor b
chr6_+_19950107 0.67 ENSDART00000181632
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr19_+_32401278 0.66 ENSDART00000184353
atxn1a
ataxin 1a
chr16_-_21047483 0.65 ENSDART00000136235
cbx3b
chromobox homolog 3b
chr11_+_18216404 0.65 ENSDART00000086437
tmcc1b
transmembrane and coiled-coil domain family 1b
chr20_-_40367493 0.64 ENSDART00000075096
smpdl3a
sphingomyelin phosphodiesterase, acid-like 3A
chr17_-_11357851 0.64 ENSDART00000153915
si:ch211-185a18.2
si:ch211-185a18.2
chr21_-_36571804 0.64 ENSDART00000138129
wwc1
WW and C2 domain containing 1
chr3_+_22036113 0.64 ENSDART00000132190
cdc27
cell division cycle 27
chr8_-_23599096 0.63 ENSDART00000183096
slc38a5b
solute carrier family 38, member 5b
chr5_-_23574234 0.62 ENSDART00000002453
cwc15
CWC15 spliceosome-associated protein homolog (S. cerevisiae)
chr19_+_42086862 0.62 ENSDART00000151605
nfyc
nuclear transcription factor Y, gamma
chr3_+_22035863 0.61 ENSDART00000177169
cdc27
cell division cycle 27
chr7_-_64770456 0.60 ENSDART00000192618
zdhhc21
zinc finger, DHHC-type containing 21
chr5_+_65087226 0.60 ENSDART00000183187
ptrh1
peptidyl-tRNA hydrolase 1 homolog
chr19_+_15443540 0.60 ENSDART00000193355
lin28a
lin-28 homolog A (C. elegans)
chr12_-_22379421 0.59 ENSDART00000187875
si:dkey-38p12.3
si:dkey-38p12.3
chr12_-_17152139 0.58 ENSDART00000152478
stambpl1
STAM binding protein-like 1
chr11_+_18873619 0.58 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr5_+_63288599 0.58 ENSDART00000140065
si:ch73-37h15.2
si:ch73-37h15.2
chr11_+_43740949 0.58 ENSDART00000189296
CU862021.1

chr25_+_15273370 0.58 ENSDART00000045659
tcp11l1
t-complex 11, testis-specific-like 1
chr7_+_31130667 0.58 ENSDART00000173937
tjp1a
tight junction protein 1a
chr12_+_19036380 0.58 ENSDART00000153086
ENSDART00000181060
kctd17
potassium channel tetramerization domain containing 17
chr14_+_20929586 0.57 ENSDART00000106198
ENSDART00000166366
zgc:66433
zgc:66433
chr17_-_13058515 0.57 ENSDART00000172450
ENSDART00000170255
CU469462.1

chr17_-_8727699 0.57 ENSDART00000049236
ENSDART00000149505
ENSDART00000148619
ENSDART00000149668
ENSDART00000148827
ctbp2a
C-terminal binding protein 2a
chr24_-_25166720 0.57 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr2_-_29994726 0.57 ENSDART00000163350
cnpy1
canopy1
chr19_+_46158078 0.57 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr23_+_45027263 0.56 ENSDART00000058364
hmgb2b
high mobility group box 2b
chr10_+_10386435 0.56 ENSDART00000179214
ENSDART00000189799
ENSDART00000193875
sardh
sarcosine dehydrogenase
chr14_+_45259644 0.56 ENSDART00000168270
CABZ01048053.1

chr14_+_46342882 0.56 ENSDART00000193707
ENSDART00000060577
tmem33
transmembrane protein 33
chr16_+_12812214 0.56 ENSDART00000124875
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr6_+_6662479 0.55 ENSDART00000065568
zgc:113227
zgc:113227
chr4_+_279669 0.55 ENSDART00000184884
CABZ01085275.1

chr9_-_32684008 0.55 ENSDART00000041751
ercc1
excision repair cross-complementation group 1
chr18_-_37252036 0.54 ENSDART00000132230
six5
SIX homeobox 5
chr20_+_49787584 0.54 ENSDART00000193458
ENSDART00000181511
ENSDART00000185850
ENSDART00000185613
ENSDART00000191671
CABZ01078261.1

chr7_+_24889783 0.54 ENSDART00000005329
ENSDART00000159955
mark2b
MAP/microtubule affinity-regulating kinase 2b
chr12_+_14084291 0.54 ENSDART00000189734
si:ch211-217a12.1
si:ch211-217a12.1
chr2_-_5723786 0.53 ENSDART00000100924
cwc25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr24_-_25166416 0.53 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr1_+_2712956 0.53 ENSDART00000126093
gpc6a
glypican 6a
chr13_+_39208542 0.53 ENSDART00000147971
fam135a
family with sequence similarity 135, member A
chr3_+_36127287 0.53 ENSDART00000058605
ENSDART00000182500
scpep1
serine carboxypeptidase 1
chr1_-_28473350 0.52 ENSDART00000190608
ENSDART00000148175
si:ch1073-440b2.1
si:ch1073-440b2.1
chr3_+_12593558 0.52 ENSDART00000186891
ENSDART00000159252
abca3b
ATP-binding cassette, sub-family A (ABC1), member 3b
chr24_+_14801844 0.52 ENSDART00000141620
pi15a
peptidase inhibitor 15a
chr11_-_31226578 0.52 ENSDART00000109698
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr20_+_18943406 0.52 ENSDART00000193590
mtmr9
myotubularin related protein 9
chr9_+_12948511 0.51 ENSDART00000135797
si:dkey-230p4.1
si:dkey-230p4.1
chr12_-_33789006 0.51 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr5_-_40024902 0.51 ENSDART00000017451
cds1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr16_+_12812472 0.50 ENSDART00000008535
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr16_-_42152145 0.50 ENSDART00000038748
dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr9_-_22057658 0.50 ENSDART00000101944
crygmxl1
crystallin, gamma MX, like 1
chr25_+_17860962 0.50 ENSDART00000163153
pth1a
parathyroid hormone 1a
chr2_-_58183499 0.50 ENSDART00000172281
ENSDART00000186262
si:ch1073-185p12.2
si:ch1073-185p12.2
chr14_+_20156477 0.49 ENSDART00000123434
fmr1
fragile X mental retardation 1
chr12_-_3778848 0.49 ENSDART00000152128
si:ch211-166g5.4
si:ch211-166g5.4
chr17_-_5352924 0.48 ENSDART00000167275
supt3h
SPT3 homolog, SAGA and STAGA complex component
chr5_+_61361815 0.48 ENSDART00000009507
gatsl2
GATS protein-like 2
chr23_+_2717950 0.48 ENSDART00000137641
ncoa6
nuclear receptor coactivator 6
chr12_-_33789218 0.47 ENSDART00000193258
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr16_-_42151909 0.47 ENSDART00000160950
dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr22_+_20169352 0.46 ENSDART00000169055
ENSDART00000061617
hmg20b
high mobility group 20B
chr11_+_39935154 0.46 ENSDART00000187653
vamp3
vesicle-associated membrane protein 3 (cellubrevin)
chr8_-_25771474 0.46 ENSDART00000193883
suv39h1b
suppressor of variegation 3-9 homolog 1b
chr25_-_3808635 0.46 ENSDART00000075659
ENSDART00000154691
gatd1
glutamine amidotransferase like class 1 domain containing 1
chr18_+_44703343 0.46 ENSDART00000131510
b3gnt2l
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr17_-_29213710 0.46 ENSDART00000076481
ehd4
EH-domain containing 4
chr22_-_14262115 0.46 ENSDART00000168264
si:ch211-246m6.5
si:ch211-246m6.5
chr24_+_19518570 0.45 ENSDART00000056081
sulf1
sulfatase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.4 1.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.4 2.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.2 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.3 0.9 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.3 1.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 1.2 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.2 1.2 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.2 2.6 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 0.2 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.2 0.6 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 0.6 GO:1901052 sarcosine metabolic process(GO:1901052)
0.2 1.1 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.2 1.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.2 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 1.6 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 1.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.2 0.6 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.2 0.9 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 1.4 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 0.8 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 2.3 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 1.8 GO:0090398 cellular senescence(GO:0090398)
0.1 4.7 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.1 GO:0046070 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.7 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.7 GO:0007603 phototransduction, visible light(GO:0007603)
0.1 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.8 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 1.1 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.1 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.8 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.7 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 1.2 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.4 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 1.7 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.6 GO:0032475 otolith formation(GO:0032475)
0.1 1.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.5 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.8 GO:0046850 regulation of bone remodeling(GO:0046850)
0.1 0.7 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.9 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 1.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816)
0.1 0.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0030826 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 4.6 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 1.5 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.4 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.1 1.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.7 GO:0009303 rRNA transcription(GO:0009303) swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.1 GO:0046660 female sex differentiation(GO:0046660)
0.1 0.6 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 1.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.9 GO:0007032 endosome organization(GO:0007032)
0.0 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0 0.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 1.7 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.3 GO:0061055 myotome development(GO:0061055)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:0008354 germ cell migration(GO:0008354)
0.0 1.1 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.5 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 2.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 1.4 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 1.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.5 GO:0007338 single fertilization(GO:0007338)
0.0 0.7 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 2.4 GO:0016573 histone acetylation(GO:0016573)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.5 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0009408 response to heat(GO:0009408)
0.0 2.0 GO:0090504 epiboly(GO:0090504)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 1.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0006298 mismatch repair(GO:0006298)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.7 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 2.0 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.1 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.5 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.7 GO:0044744 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.4 1.5 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 3.7 GO:0002102 podosome(GO:0002102)
0.2 2.0 GO:0005688 U6 snRNP(GO:0005688)
0.2 2.0 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.5 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 1.2 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.1 GO:0089701 U2AF(GO:0089701)
0.1 3.1 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 0.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.2 GO:0015030 Cajal body(GO:0015030)
0.1 0.9 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.3 GO:0043034 costamere(GO:0043034)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.3 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.9 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.0 GO:0071565 nBAF complex(GO:0071565)
0.0 4.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0043296 apical junction complex(GO:0043296)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0016586 RSC complex(GO:0016586)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.6 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.5 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0035197 siRNA binding(GO:0035197)
0.4 1.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.3 1.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 1.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.3 1.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 1.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.2 0.9 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 1.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 1.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.7 GO:0070513 death domain binding(GO:0070513)
0.1 0.6 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 1.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.5 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 1.1 GO:0008494 translation activator activity(GO:0008494)
0.1 1.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.3 GO:2001069 glycogen binding(GO:2001069)
0.1 1.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.8 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 1.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 3.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.2 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 2.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 1.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.6 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.7 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 4.7 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.9 GO:0060090 binding, bridging(GO:0060090)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 3.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.2 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 5.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.9 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.6 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts