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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for irx2a

Z-value: 0.38

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Transcription factors associated with irx2a

Gene Symbol Gene ID Gene Info
irx2a
ENSDARG00000001785 iroquois homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irx2adr11_v1_chr16_-_563732_5637320.263.0e-01Click!

Activity profile of irx2a motif

Sorted Z-values of irx2a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_17083180 1.35 ENSDART00000170083
fam166b
family with sequence similarity 166, member B
chr12_-_11649690 1.15 ENSDART00000149713
btbd16
BTB (POZ) domain containing 16
chr5_-_22621417 1.00 ENSDART00000138716
zgc:113208
zgc:113208
chr12_+_2870671 0.99 ENSDART00000165225
prkar1ab
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b
chr18_-_29961784 0.88 ENSDART00000135601
ENSDART00000140661
si:ch73-103b9.2
si:ch73-103b9.2
chr12_+_36891483 0.86 ENSDART00000048927
cox10
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr1_+_55239710 0.82 ENSDART00000174846
si:ch211-286b5.2
si:ch211-286b5.2
chr13_-_11971148 0.80 ENSDART00000066230
ENSDART00000185614
ARL3 (1 of many)
zgc:110197
chr23_-_28141419 0.78 ENSDART00000133039
tac3a
tachykinin 3a
chr23_+_42819221 0.72 ENSDART00000180495
myl9a
myosin, light chain 9a, regulatory
chr3_+_55105066 0.72 ENSDART00000110848
si:ch211-5k11.8
si:ch211-5k11.8
chr19_-_41069573 0.70 ENSDART00000111982
ENSDART00000193142
sgce
sarcoglycan, epsilon
chr14_-_33360344 0.67 ENSDART00000181291
pimr117
Pim proto-oncogene, serine/threonine kinase, related 117
chr22_-_21314821 0.66 ENSDART00000105546
ENSDART00000135388
cks2
CDC28 protein kinase regulatory subunit 2
chr12_+_10163585 0.62 ENSDART00000106191
psmc5
proteasome 26S subunit, ATPase 5
chr6_-_24320268 0.54 ENSDART00000171733
si:dkeyp-85h7.1
si:dkeyp-85h7.1
chr6_-_54845622 0.52 ENSDART00000048887
csrp1b
cysteine and glycine-rich protein 1b
chr19_+_9004256 0.51 ENSDART00000186401
ENSDART00000091443
si:ch211-81a5.1
si:ch211-81a5.1
chr21_+_22423286 0.50 ENSDART00000133190
capslb
calcyphosine-like b
chr5_+_338154 0.49 ENSDART00000191743
rnf170
ring finger protein 170
chr14_-_48103207 0.48 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr6_-_7720332 0.47 ENSDART00000135945
rpsa
ribosomal protein SA
chr24_-_37955993 0.46 ENSDART00000041805
metrn
meteorin, glial cell differentiation regulator
chr8_+_26565512 0.45 ENSDART00000140980
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr14_-_26400501 0.45 ENSDART00000054189
pimr212
Pim proto-oncogene, serine/threonine kinase, related 212
chr24_-_7632187 0.44 ENSDART00000041714
atp6v0a1b
ATPase H+ transporting V0 subunit a1b
chr23_+_4299887 0.44 ENSDART00000132604
l3mbtl1a
l(3)mbt-like 1a (Drosophila)
chr21_+_723998 0.42 ENSDART00000160956
oaz1b
ornithine decarboxylase antizyme 1b
chr13_+_32636197 0.42 ENSDART00000141057
si:ch211-206k20.5
si:ch211-206k20.5
chr22_+_7480465 0.41 ENSDART00000034545
CELA1 (1 of many)
zgc:92745
chr12_+_27024676 0.41 ENSDART00000153104
msl1b
male-specific lethal 1 homolog b (Drosophila)
chr7_+_17255705 0.40 ENSDART00000053357
ENSDART00000167849
ENSDART00000165833
nitr9
si:ch73-46n24.1
novel immune-type receptor 9
si:ch73-46n24.1
chr23_+_23658474 0.39 ENSDART00000162838
agrn
agrin
chr21_-_37733287 0.39 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr1_-_49544601 0.39 ENSDART00000145960
slc47a2.2
solute carrier family 47 (multidrug and toxin extrusion), member 2.2
chr2_+_44545912 0.38 ENSDART00000155362
si:dkeyp-94h10.5
si:dkeyp-94h10.5
chr1_+_52518176 0.37 ENSDART00000003278
tacr3l
tachykinin receptor 3-like
chr7_-_5316901 0.37 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
si:cabz01074946.1
chr2_+_34138376 0.37 ENSDART00000137170
dars2
aspartyl-tRNA synthetase 2, mitochondrial
chr9_-_56231387 0.37 ENSDART00000149851
rpl31
ribosomal protein L31
chr3_+_62161184 0.37 ENSDART00000090370
ENSDART00000192665
noxo1a
NADPH oxidase organizer 1a
chr6_-_54845083 0.37 ENSDART00000148815
csrp1b
cysteine and glycine-rich protein 1b
chr14_-_28568107 0.37 ENSDART00000042850
ENSDART00000145502
insb
preproinsulin b
chr21_+_45223194 0.36 ENSDART00000150902
si:ch73-269m14.3
si:ch73-269m14.3
chr20_-_5267600 0.35 ENSDART00000099258
cyp46a1.4
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr12_+_28854410 0.35 ENSDART00000152991
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr8_-_23573084 0.35 ENSDART00000139084
wasb
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr16_-_52821023 0.35 ENSDART00000074718
spire1b
spire-type actin nucleation factor 1b
chr13_-_44738574 0.35 ENSDART00000074761
zfand3
zinc finger, AN1-type domain 3
chr21_+_6961635 0.35 ENSDART00000137281
si:ch211-93g21.2
si:ch211-93g21.2
chr16_-_40508624 0.34 ENSDART00000075718
ndufaf6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr7_-_27033080 0.33 ENSDART00000173516
nucb2a
nucleobindin 2a
chr1_-_13968153 0.32 ENSDART00000103383
elf2b
E74-like factor 2b (ets domain transcription factor)
chr18_-_14691727 0.32 ENSDART00000010129
pdf
peptide deformylase, mitochondrial
chr25_+_34845115 0.31 ENSDART00000061996
tmem231
transmembrane protein 231
chr12_+_46960579 0.31 ENSDART00000149032
oat
ornithine aminotransferase
chr8_+_23213320 0.31 ENSDART00000032996
ENSDART00000137536
ppdpfa
pancreatic progenitor cell differentiation and proliferation factor a
chr8_+_471342 0.30 ENSDART00000167205
nudt12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr2_+_22795494 0.30 ENSDART00000042255
rab6bb
RAB6B, member RAS oncogene family b
chr24_-_25186895 0.30 ENSDART00000081029
plcxd2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr25_-_36286186 0.29 ENSDART00000182398
slc7a10b
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10b
chr5_+_37785152 0.29 ENSDART00000053511
ENSDART00000189812
myo1ca
myosin Ic, paralog a
chr11_+_3254252 0.28 ENSDART00000123568
pmela
premelanosome protein a
chr6_-_13200585 0.28 ENSDART00000185321
eef1b2
eukaryotic translation elongation factor 1 beta 2
chr8_-_25011157 0.28 ENSDART00000078795
ahcyl1
adenosylhomocysteinase-like 1
chr14_+_8476769 0.28 ENSDART00000131773
dnajc4
DnaJ (Hsp40) homolog, subfamily C, member 4
chr1_-_44940830 0.27 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
tmem176
transmembrane protein 176
chr17_-_43428397 0.26 ENSDART00000043866
plk4
polo-like kinase 4 (Drosophila)
chr10_-_33379850 0.26 ENSDART00000186924
ska2
spindle and kinetochore associated complex subunit 2
chr22_+_21972824 0.25 ENSDART00000183708
ENSDART00000133739
gna15.3
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3
chr13_+_28512863 0.25 ENSDART00000043117
fbxw4
F-box and WD repeat domain containing 4
chr13_+_45709380 0.25 ENSDART00000192862
si:ch211-62a1.3
si:ch211-62a1.3
chr3_-_2589704 0.25 ENSDART00000187239
si:dkey-217f16.5
si:dkey-217f16.5
chr23_+_36653376 0.25 ENSDART00000053189
gpr182
G protein-coupled receptor 182
chr2_+_47581997 0.25 ENSDART00000112579
scg2b
secretogranin II (chromogranin C), b
chr17_-_53329704 0.24 ENSDART00000193895
exd1
exonuclease 3'-5' domain containing 1
chr21_-_2238277 0.24 ENSDART00000165754
si:dkey-50i6.6
si:dkey-50i6.6
chr17_-_51938663 0.24 ENSDART00000179784
ERG28
ergosterol biosynthesis 28 homolog
chr19_+_34742706 0.24 ENSDART00000103276
fam206a
family with sequence similarity 206, member A
chr3_+_26223376 0.24 ENSDART00000128284
nudt9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr13_-_32635859 0.23 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr17_+_24006792 0.23 ENSDART00000122415
si:ch211-63b16.4
si:ch211-63b16.4
chr6_-_32314913 0.23 ENSDART00000051779
atg4c
autophagy related 4C, cysteine peptidase
chr4_-_12725513 0.23 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr17_+_53284040 0.23 ENSDART00000165368
atxn3
ataxin 3
chr19_+_30387999 0.22 ENSDART00000145396
tspan13b
tetraspanin 13b
chr21_+_21339311 0.22 ENSDART00000137693
ENSDART00000161820
sdhaf1
si:ch211-191j22.3
succinate dehydrogenase complex assembly factor 1
si:ch211-191j22.3
chr6_+_14980761 0.22 ENSDART00000087782
mrps9
mitochondrial ribosomal protein S9
chr23_+_43855618 0.21 ENSDART00000156842
cnga1
cyclic nucleotide gated channel alpha 1
chr16_+_40508882 0.21 ENSDART00000126129
nagpa
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr21_-_9991502 0.21 ENSDART00000169320
esm1
endothelial cell-specific molecule 1
chr7_-_24644893 0.20 ENSDART00000048921
rgp1
GP1 homolog, RAB6A GEF complex partner 1
chr15_+_5973909 0.20 ENSDART00000126886
ENSDART00000189618
igsf5b
immunoglobulin superfamily, member 5b
chr25_-_35996141 0.20 ENSDART00000149074
sall1b
spalt-like transcription factor 1b
chr5_-_6508250 0.20 ENSDART00000060535
crybb3
crystallin, beta B3
chr12_-_46959990 0.20 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr23_+_32499916 0.20 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr6_+_28205284 0.19 ENSDART00000160707
ENSDART00000190509
smx5
LSM2 (1 of many)
smx5
si:ch73-14h10.2
chr7_-_38638809 0.19 ENSDART00000144341
c6ast4
six-cysteine containing astacin protease 4
chr8_-_30791266 0.19 ENSDART00000062220
gstt1a
glutathione S-transferase theta 1a
chr6_-_39218609 0.19 ENSDART00000133305
os9
osteosarcoma amplified 9, endoplasmic reticulum lectin
chr1_-_7582859 0.19 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr20_-_26929685 0.18 ENSDART00000132556
ftr79
finTRIM family, member 79
chr1_+_20635190 0.18 ENSDART00000145418
ENSDART00000148518
ENSDART00000139461
ENSDART00000102969
ENSDART00000166479
spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_+_9533008 0.18 ENSDART00000104607
fam131ba
family with sequence similarity 131, member Ba
chr12_+_26632448 0.18 ENSDART00000185762
arhgap12b
Rho GTPase activating protein 12b
chr25_-_13676682 0.18 ENSDART00000090226
znf319b
zinc finger protein 319b
chr19_+_30388186 0.18 ENSDART00000103474
tspan13b
tetraspanin 13b
chr7_+_17374560 0.18 ENSDART00000172272
ENSDART00000073467
nitr7a
novel immune-type receptor 7a
chr21_+_5915041 0.18 ENSDART00000151370
prodha
proline dehydrogenase (oxidase) 1a
chr21_-_4244514 0.17 ENSDART00000065880
uck1
uridine-cytidine kinase 1
chr25_+_25438322 0.17 ENSDART00000150364
LRRC56
si:ch211-103e16.5
chr7_-_23873173 0.17 ENSDART00000101408
zgc:162171
zgc:162171
chr21_-_2248239 0.17 ENSDART00000169448
si:ch73-299h12.1
si:ch73-299h12.1
chr8_-_30791089 0.17 ENSDART00000147332
gstt1a
glutathione S-transferase theta 1a
chr8_+_23009662 0.17 ENSDART00000030885
uckl1a
uridine-cytidine kinase 1-like 1a
chr21_-_26483237 0.17 ENSDART00000169072
ENSDART00000147947
ankhd1
ankyrin repeat and KH domain containing 1
chr1_+_24366110 0.16 ENSDART00000139913
pimr178
Pim proto-oncogene, serine/threonine kinase, related 178
chr4_-_8093753 0.16 ENSDART00000133434
wnk1b
WNK lysine deficient protein kinase 1b
chr16_+_32131568 0.16 ENSDART00000171454
sphk2
sphingosine kinase 2
chr17_-_9995667 0.16 ENSDART00000148463
snx6
sorting nexin 6
chr24_-_12938922 0.16 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr22_-_13165186 0.16 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr16_-_19349318 0.15 ENSDART00000020821
dnah11
dynein, axonemal, heavy chain 11
chr3_+_57997980 0.15 ENSDART00000168477
ENSDART00000193840
pycr1a
pyrroline-5-carboxylate reductase 1a
chr20_+_26349002 0.14 ENSDART00000152842
syne1a
spectrin repeat containing, nuclear envelope 1a
chr25_+_7671640 0.14 ENSDART00000145367
kcnj11l
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr22_-_30948457 0.14 ENSDART00000139887
ssuh2.1
ssu-2 homolog, tandem duplicate 1
chr11_-_21014572 0.14 ENSDART00000042220
slc6a14
solute carrier family 6 (amino acid transporter), member 14
chr20_+_49119633 0.14 ENSDART00000151435
cd109
CD109 molecule
chr24_+_2961098 0.14 ENSDART00000163760
ENSDART00000170835
eci2
enoyl-CoA delta isomerase 2
chr12_-_10275320 0.14 ENSDART00000170078
mpp2b
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr11_-_41130239 0.14 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr8_+_44926946 0.13 ENSDART00000098567
zgc:154046
zgc:154046
chr10_+_3875716 0.13 ENSDART00000189268
ENSDART00000180624
TTC28
tetratricopeptide repeat domain 28
chr7_-_41916505 0.13 ENSDART00000185785
dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr22_-_28226948 0.13 ENSDART00000147686
si:dkey-222p3.1
si:dkey-222p3.1
chr1_+_44941031 0.13 ENSDART00000141145
si:dkey-9i23.16
si:dkey-9i23.16
chr16_+_34479064 0.13 ENSDART00000159965
si:ch211-255i3.4
si:ch211-255i3.4
chr25_-_3759322 0.12 ENSDART00000088077
zgc:158398
zgc:158398
chr2_-_32386598 0.12 ENSDART00000145575
ubtfl
upstream binding transcription factor, like
chr2_+_47582681 0.12 ENSDART00000187579
scg2b
secretogranin II (chromogranin C), b
chr11_-_3574311 0.12 ENSDART00000167064
si:dkey-33m11.7
si:dkey-33m11.7
chr2_+_35854242 0.12 ENSDART00000134918
dhx9
DEAH (Asp-Glu-Ala-His) box helicase 9
chr5_+_31860043 0.12 ENSDART00000036235
ENSDART00000140541
iscub
iron-sulfur cluster assembly enzyme b
chr25_-_6557854 0.12 ENSDART00000181740
cspg4
chondroitin sulfate proteoglycan 4
chr3_+_28831450 0.12 ENSDART00000055422
flr
fleer
chr8_+_68864 0.11 ENSDART00000164574
prr16
proline rich 16
chr19_+_10832092 0.11 ENSDART00000191851
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr17_+_45404758 0.11 ENSDART00000147557
tagapa
T cell activation RhoGTPase activating protein a
chr12_-_47899497 0.11 ENSDART00000162219
QRFPR
pyroglutamylated RFamide peptide receptor
chr17_+_8323348 0.11 ENSDART00000169900
cdc42bpaa
CDC42 binding protein kinase alpha (DMPK-like) a
chr8_-_20858676 0.11 ENSDART00000018515
dohh
deoxyhypusine hydroxylase/monooxygenase
chr7_+_23875269 0.11 ENSDART00000101406
rab39bb
RAB39B, member RAS oncogene family b
chr6_-_18698006 0.10 ENSDART00000170128
rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr3_-_58798377 0.10 ENSDART00000161248
si:ch73-281f12.4
si:ch73-281f12.4
chr19_+_8973042 0.10 ENSDART00000039597
crabp2b
cellular retinoic acid binding protein 2, b
chr23_-_4404105 0.10 ENSDART00000146941
si:ch73-142c19.1
si:ch73-142c19.1
chr17_+_43468732 0.10 ENSDART00000055487
chmp3
charged multivesicular body protein 3
chr22_+_24378064 0.10 ENSDART00000180592
BX649608.2

chr19_+_34311374 0.10 ENSDART00000086617
gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr7_+_6879534 0.09 ENSDART00000157731
zgc:175248
zgc:175248
chr6_+_12326267 0.09 ENSDART00000155101
si:dkey-276j7.3
si:dkey-276j7.3
chr19_+_5480327 0.09 ENSDART00000148794
jupb
junction plakoglobin b
chr7_+_4384863 0.08 ENSDART00000042955
ENSDART00000134653
slc12a10.3
slc12a10.3 solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 3
chr3_-_32611833 0.08 ENSDART00000151282
si:ch73-248e21.5
si:ch73-248e21.5
chr20_-_17259573 0.08 ENSDART00000166397
AL928808.1

chr12_-_32426685 0.08 ENSDART00000105574
enpp7.2
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 2
chr13_+_4205724 0.08 ENSDART00000134105
dlk2
delta-like 2 homolog (Drosophila)
chr9_-_23944470 0.08 ENSDART00000138754
col6a3
collagen, type VI, alpha 3
chr6_-_18698669 0.08 ENSDART00000168554
ENSDART00000175205
rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr3_+_25849560 0.08 ENSDART00000007119
mfsd6l
major facilitator superfamily domain containing 6-like
chr16_+_24681177 0.07 ENSDART00000058956
ENSDART00000189335
ywhabl
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr9_+_31282161 0.07 ENSDART00000010774
zic2a
zic family member 2 (odd-paired homolog, Drosophila), a
chr23_+_19606291 0.07 ENSDART00000139415
flnb
filamin B, beta (actin binding protein 278)
chr14_-_25985698 0.07 ENSDART00000172909
ENSDART00000123053
atox1
antioxidant 1 copper chaperone
chr13_-_40726865 0.07 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr7_+_21272833 0.07 ENSDART00000052942
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr21_-_4032650 0.07 ENSDART00000151648
ntng2b
netrin g2b
chr6_-_18698456 0.07 ENSDART00000166587
rhbdl3
rhomboid, veinlet-like 3 (Drosophila)
chr7_-_18656069 0.06 ENSDART00000021559
coro1b
coronin, actin binding protein, 1B
chr21_-_31238244 0.06 ENSDART00000159678
tpst1l
tyrosylprotein sulfotransferase 1, like
chr3_+_38793499 0.06 ENSDART00000083394
kcnj19a
potassium voltage-gated channel subfamily J member 19a
chr11_+_44579865 0.06 ENSDART00000173425
nid1b
nidogen 1b
chr7_+_50464500 0.06 ENSDART00000191356
serinc4
serine incorporator 4
chr3_+_32689707 0.06 ENSDART00000029262
si:dkey-16l2.17
si:dkey-16l2.17
chr7_-_17779644 0.06 ENSDART00000128504
si:dkey-106g10.7
si:dkey-106g10.7
chr2_+_47582488 0.06 ENSDART00000149967
scg2b
secretogranin II (chromogranin C), b
chr2_-_6039757 0.06 ENSDART00000013079
scp2a
sterol carrier protein 2a
chr5_+_69868911 0.06 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr22_+_17192767 0.06 ENSDART00000130810
ENSDART00000183006
atpaf1
ATP synthase mitochondrial F1 complex assembly factor 1
chr21_-_40083432 0.06 ENSDART00000141160
ENSDART00000191195
slc13a5a
info solute carrier family 13 (sodium-dependent citrate transporter), member 5a
chr6_-_43007264 0.06 ENSDART00000124623
si:ch73-361p23.3
si:ch73-361p23.3
chr24_+_14713776 0.06 ENSDART00000134475
gdap1
ganglioside induced differentiation associated protein 1
chr13_-_15865335 0.06 ENSDART00000135186
si:ch211-57f7.7
si:ch211-57f7.7
chr12_+_20412564 0.05 ENSDART00000186783
arhgap17a
Rho GTPase activating protein 17a
chr5_-_24270989 0.05 ENSDART00000146251
si:ch211-137i24.12
si:ch211-137i24.12
chr2_+_30960351 0.05 ENSDART00000141575
lpin2
lipin 2
chr18_-_34156765 0.05 ENSDART00000059400
c18h3orf33
c18h3orf33 homolog (H. sapiens)
chr14_-_1280907 0.05 ENSDART00000186150
CABZ01081490.1

Network of associatons between targets according to the STRING database.

First level regulatory network of irx2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.4 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.6 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.3 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.3 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.1 0.3 GO:0097435 fibril organization(GO:0097435)
0.1 0.3 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.4 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.3 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.3 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0036372 opsin transport(GO:0036372)
0.0 0.9 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0006801 superoxide metabolic process(GO:0006801)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.0 GO:0019474 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.4 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.2 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 1.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.7 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 0.2 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0101006 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.0 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.9 GO:0043236 laminin binding(GO:0043236)
0.0 0.9 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.4 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters