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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for jund_batf

Z-value: 1.23

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Transcription factors associated with jund_batf

Gene Symbol Gene ID Gene Info
jund
ENSDARG00000067850 JunD proto-oncogene, AP-1 transcription factor subunit
batf
ENSDARG00000011818 basic leucine zipper transcription factor, ATF-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
batfdr11_v1_chr20_+_46572550_46572550-0.962.2e-10Click!
junddr11_v1_chr2_-_56131312_561313120.662.7e-03Click!

Activity profile of jund_batf motif

Sorted Z-values of jund_batf motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_13818061 5.19 ENSDART00000132982
ENSDART00000144856
leng9
leukocyte receptor cluster (LRC) member 9
chr7_-_52963493 5.12 ENSDART00000052029
cart3
cocaine- and amphetamine-regulated transcript 3
chr9_+_2499627 4.94 ENSDART00000160782
wipf1a
WAS/WASL interacting protein family, member 1a
chr24_+_13277573 4.75 ENSDART00000137886
si:ch211-171b20.3
si:ch211-171b20.3
chr24_+_31361407 4.61 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr6_+_7421898 4.38 ENSDART00000043946
ccdc65
coiled-coil domain containing 65
chr3_+_24197934 4.02 ENSDART00000055609
atf4b
activating transcription factor 4b
chr21_+_22845317 3.99 ENSDART00000065555
birc2
baculoviral IAP repeat containing 2
chr20_+_2134816 3.97 ENSDART00000039249
l3mbtl3
l(3)mbt-like 3 (Drosophila)
chr22_+_16497670 3.97 ENSDART00000014330
ier5
immediate early response 5
chr24_+_35827766 3.93 ENSDART00000144700
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr22_+_36914636 3.80 ENSDART00000150948
pimr205
Pim proto-oncogene, serine/threonine kinase, related 205
chr25_-_15496485 3.48 ENSDART00000140245
si:dkeyp-67e1.6
si:dkeyp-67e1.6
chr3_+_24986145 3.48 ENSDART00000055428
cbx7a
chromobox homolog 7a
chr5_+_13385837 3.36 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr1_+_135903 2.97 ENSDART00000124837
f10
coagulation factor X
chr12_+_1455147 2.84 ENSDART00000018752
cops3
COP9 signalosome subunit 3
chr20_-_2134620 2.73 ENSDART00000064375
tmem244
transmembrane protein 244
chr19_+_37118547 2.60 ENSDART00000103163
cx30.9
connexin 30.9
chr6_+_49095646 2.58 ENSDART00000103385
slc25a55a
solute carrier family 25, member 55a
chr8_-_36554675 2.46 ENSDART00000132804
ENSDART00000078746
ccdc157
coiled-coil domain containing 157
chr3_+_31621774 2.14 ENSDART00000076636
fzd2
frizzled class receptor 2
chr3_-_26017592 2.09 ENSDART00000030890
hmox1a
heme oxygenase 1a
chr4_-_69189894 2.07 ENSDART00000169596
si:ch211-209j12.1
si:ch211-209j12.1
chr20_-_32658305 2.07 ENSDART00000140622
ENSDART00000152909
si:dkey-6f10.3
si:dkey-6f10.3
chr15_-_20933574 1.99 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
usp2a
ubiquitin specific peptidase 2a
chr16_-_50203058 1.89 ENSDART00000154570
vsig10l
V-set and immunoglobulin domain containing 10 like
chr16_+_42830152 1.88 ENSDART00000159730
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr22_+_38173960 1.75 ENSDART00000010537
cp
ceruloplasmin
chr3_-_16289826 1.70 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr8_+_25900049 1.69 ENSDART00000124300
ENSDART00000127618
ENSDART00000024009
rhoab
ras homolog gene family, member Ab
chr7_-_24236364 1.68 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr3_-_26017831 1.67 ENSDART00000179982
hmox1a
heme oxygenase 1a
chr16_-_38518270 1.65 ENSDART00000131899
rspo2
R-spondin 2
chr20_+_25340814 1.64 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr11_-_2478374 1.60 ENSDART00000173205
si:ch73-267c23.10
si:ch73-267c23.10
chr25_-_15512819 1.48 ENSDART00000142684
si:dkeyp-67e1.2
si:dkeyp-67e1.2
chr25_+_27873671 1.44 ENSDART00000088817
iqub
IQ motif and ubiquitin domain containing
chr3_-_16055432 1.43 ENSDART00000123621
ENSDART00000023859
atp6v0ca
ATPase H+ transporting V0 subunit ca
chr15_-_34558579 1.40 ENSDART00000140882
ispd
isoprenoid synthase domain containing
chr10_+_31344227 1.35 ENSDART00000184470
AL845320.2

chr25_+_27873836 1.35 ENSDART00000163801
iqub
IQ motif and ubiquitin domain containing
chr24_+_26658132 1.34 ENSDART00000183081
FQ378040.1

chr17_-_33714636 1.33 ENSDART00000188500
DNAL1
si:dkey-84k17.3
chr21_+_17024002 1.33 ENSDART00000080628
arpc3
actin related protein 2/3 complex, subunit 3
chr25_-_24233884 1.32 ENSDART00000146419
si:dkey-11e23.9
si:dkey-11e23.9
chr10_+_28428222 1.32 ENSDART00000135003
si:ch211-222e20.4
si:ch211-222e20.4
chr12_+_7497882 1.31 ENSDART00000134608
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr8_+_50531709 1.28 ENSDART00000193352
PEBP4
phosphatidylethanolamine binding protein 4
chr1_-_56176976 1.17 ENSDART00000052688
c3a.1
complement component c3a, duplicate 1
chr18_-_36909773 1.16 ENSDART00000141694
si:ch211-160d20.5
si:ch211-160d20.5
chr7_+_528593 1.15 ENSDART00000091955
nrxn2b
neurexin 2b
chr12_+_19188542 1.12 ENSDART00000134726
ENSDART00000148011
ENSDART00000109541
cby1
chibby homolog 1 (Drosophila)
chr25_-_15504559 1.10 ENSDART00000139294
BX323543.5

chr1_-_40086978 1.06 ENSDART00000136990
si:dkey-117m1.4
si:dkey-117m1.4
chr13_-_20381485 1.04 ENSDART00000131351
si:ch211-270n8.1
si:ch211-270n8.1
chr18_-_5692292 1.02 ENSDART00000121503
cplx3b
complexin 3b
chr21_+_33459524 1.02 ENSDART00000053205
cd74b
CD74 molecule, major histocompatibility complex, class II invariant chain b
chr6_-_31224563 1.01 ENSDART00000104616
lepr
leptin receptor
chr10_+_42733210 0.98 ENSDART00000189832
CABZ01063556.1

chr15_-_21877726 0.97 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
zgc:162608
chr5_+_38276582 0.96 ENSDART00000158532
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr9_-_7640692 0.95 ENSDART00000135616
dnajb2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr21_+_8341774 0.88 ENSDART00000129749
ENSDART00000055325
ENSDART00000133804
psmb7
proteasome subunit beta 7
chr11_-_39202915 0.88 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr5_-_57480660 0.85 ENSDART00000147875
ENSDART00000142776
si:ch211-202f5.2
si:ch211-202f5.2
chr3_-_41535647 0.82 ENSDART00000153723
ENSDART00000154198
si:ch211-222n22.1
si:ch211-222n22.1
chr14_-_26400501 0.82 ENSDART00000054189
pimr212
Pim proto-oncogene, serine/threonine kinase, related 212
chr23_-_44848961 0.79 ENSDART00000136839
wu:fb72h05
wu:fb72h05
chr14_+_49382180 0.79 ENSDART00000158329
tnip1
TNFAIP3 interacting protein 1
chr22_+_19365220 0.78 ENSDART00000132781
ENSDART00000135672
ENSDART00000153630
si:dkey-21e2.12
si:dkey-21e2.12
chr24_-_21404367 0.77 ENSDART00000152093
atp8a2
ATPase phospholipid transporting 8A2
chr25_-_18330503 0.75 ENSDART00000104496
dusp6
dual specificity phosphatase 6
chr23_+_29883216 0.72 ENSDART00000113367
ENSDART00000149761
ENSDART00000148706
aurkaip1
aurora kinase A interacting protein 1
chr5_-_30924347 0.70 ENSDART00000111749
ENSDART00000086564
ENSDART00000153909
spns2
spinster homolog 2 (Drosophila)
chr13_-_5257303 0.68 ENSDART00000110610
si:dkey-78p8.1
si:dkey-78p8.1
chr7_+_24496894 0.67 ENSDART00000149994
nelfa
negative elongation factor complex member A
chr23_-_18024543 0.67 ENSDART00000139695
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr19_+_48102560 0.66 ENSDART00000164464
utp18
UTP18 small subunit (SSU) processome component
chr12_+_9551667 0.64 ENSDART00000048493
ENSDART00000166178
p4ha1a
prolyl 4-hydroxylase, alpha polypeptide I a
chr16_-_32184460 0.63 ENSDART00000102027
kpna5
karyopherin alpha 5 (importin alpha 6)
chr5_-_30984010 0.63 ENSDART00000182367
spns3
spinster homolog 3 (Drosophila)
chr8_+_29856013 0.62 ENSDART00000061981
ENSDART00000149610
hsd17b3
hydroxysteroid (17-beta) dehydrogenase 3
chr23_+_40109353 0.62 ENSDART00000149249
ghrhrl
growth hormone releasing hormone receptor, like
chr6_-_48317562 0.62 ENSDART00000103425
st7l
suppression of tumorigenicity 7 like
chr15_+_29123031 0.60 ENSDART00000133988
ENSDART00000060030
zgc:101731
zgc:101731
chr9_-_2572790 0.60 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr13_+_10621257 0.60 ENSDART00000008603
prepl
prolyl endopeptidase-like
chr22_+_19247255 0.58 ENSDART00000144053
si:dkey-21e2.10
si:dkey-21e2.10
chr16_+_49005321 0.58 ENSDART00000160919
CABZ01068499.1

chr17_-_6536305 0.57 ENSDART00000154855
cenpo
centromere protein O
chr25_+_7423770 0.56 ENSDART00000155458
ubap1la
ubiquitin associated protein 1-like a
chr5_+_17624463 0.55 ENSDART00000183869
ENSDART00000081064
fbrsl1
fibrosin-like 1
chr13_-_50624743 0.54 ENSDART00000167949
vox
ventral homeobox
chr20_+_34868933 0.54 ENSDART00000153006
ankef1a
ankyrin repeat and EF-hand domain containing 1a
chr20_-_35040041 0.54 ENSDART00000131919
kif26bb
kinesin family member 26Bb
chr12_+_41348969 0.53 ENSDART00000171352
si:ch211-27e6.1
si:ch211-27e6.1
chr21_+_9628854 0.53 ENSDART00000161753
ENSDART00000160711
mapk10
mitogen-activated protein kinase 10
chr14_+_48062180 0.53 ENSDART00000056713
ppid
peptidylprolyl isomerase D
chr10_-_40514643 0.52 ENSDART00000140705
taar19k
trace amine associated receptor 19k
chr2_-_6182098 0.52 ENSDART00000156167
si:ch73-182a11.2
si:ch73-182a11.2
chr3_+_60044780 0.51 ENSDART00000080437
zgc:113030
zgc:113030
chr1_-_22834824 0.49 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr18_-_13360106 0.48 ENSDART00000091512
cmip
c-Maf inducing protein
chr18_+_45114392 0.46 ENSDART00000172328
large2
LARGE xylosyl- and glucuronyltransferase 2
chr5_-_30487822 0.45 ENSDART00000189288
ENSDART00000183201
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr2_-_49997055 0.45 ENSDART00000140294
si:ch211-106n13.3
si:ch211-106n13.3
chr8_+_8973425 0.44 ENSDART00000066107
bcap31
B cell receptor associated protein 31
chr17_+_23770848 0.43 ENSDART00000079646
kcnk18
potassium channel, subfamily K, member 18
chr5_-_43959972 0.43 ENSDART00000180517
si:ch211-204c21.1
si:ch211-204c21.1
chr19_-_36675023 0.42 ENSDART00000132471
csmd2
CUB and Sushi multiple domains 2
chr3_+_37707432 0.42 ENSDART00000151236
map3k14a
mitogen-activated protein kinase kinase kinase 14a
chr23_+_20863145 0.40 ENSDART00000129992
pax7b
paired box 7b
chr7_-_37563883 0.40 ENSDART00000148805
nod2
nucleotide-binding oligomerization domain containing 2
chr23_+_9067131 0.39 ENSDART00000144533
ccm2l
cerebral cavernous malformation 2-like
chr24_+_7800486 0.38 ENSDART00000145504
ptprh
protein tyrosine phosphatase, receptor type, h
chr1_+_7517454 0.38 ENSDART00000016139
lancl1
LanC antibiotic synthetase component C-like 1 (bacterial)
chr4_-_72080351 0.38 ENSDART00000174925
LO017820.1

chr7_-_35408618 0.38 ENSDART00000074963
lpcat2
lysophosphatidylcholine acyltransferase 2
chr2_-_6232517 0.38 ENSDART00000139842
rec8a
REC8 meiotic recombination protein a
chr19_+_33093395 0.36 ENSDART00000019459
fam91a1
family with sequence similarity 91, member A1
chr12_+_21684239 0.36 ENSDART00000043546
mrpl27
mitochondrial ribosomal protein L27
chr3_-_61185746 0.36 ENSDART00000028219
pvalb4
parvalbumin 4
chr17_-_52091999 0.36 ENSDART00000019766
tgfb3
transforming growth factor, beta 3
chr21_+_25071805 0.34 ENSDART00000078651
dixdc1b
DIX domain containing 1b
chr5_+_61556172 0.34 ENSDART00000131937
orai2
ORAI calcium release-activated calcium modulator 2
chr25_-_11026907 0.33 ENSDART00000156846
mespbb
mesoderm posterior bb
chr2_+_30379650 0.33 ENSDART00000129542
crispld1b
cysteine-rich secretory protein LCCL domain containing 1b
chr18_-_28938912 0.30 ENSDART00000136201
si:ch211-174j14.2
si:ch211-174j14.2
chr9_+_38372216 0.30 ENSDART00000141895
plcd4b
phospholipase C, delta 4b
chr13_-_21701323 0.30 ENSDART00000164112
si:dkey-191g9.7
si:dkey-191g9.7
chr4_-_76270779 0.30 ENSDART00000183709
ENSDART00000192689
si:ch211-106j21.4
si:ch211-106j21.4
chr5_-_41531629 0.30 ENSDART00000051082
akr1a1a
aldo-keto reductase family 1, member A1a (aldehyde reductase)
chr20_-_42972599 0.29 ENSDART00000100751
pomcb
proopiomelanocortin b
chr13_-_50624173 0.29 ENSDART00000184181
vox
ventral homeobox
chr7_-_35409027 0.28 ENSDART00000128334
lpcat2
lysophosphatidylcholine acyltransferase 2
chr4_+_68087932 0.28 ENSDART00000150494
znf1096
zinc finger protein 1096
chr24_+_17260001 0.28 ENSDART00000066765
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr23_+_39558508 0.28 ENSDART00000017902
camk1gb
calcium/calmodulin-dependent protein kinase IGb
chr24_+_26039464 0.28 ENSDART00000131017
tnk2a
tyrosine kinase, non-receptor, 2a
chr19_+_40856807 0.28 ENSDART00000139083
gngt1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr19_+_42142381 0.28 ENSDART00000129915
kcnq4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr8_+_39634114 0.27 ENSDART00000144293
msi1
musashi RNA-binding protein 1
chr21_+_5888641 0.26 ENSDART00000091331
prodha
proline dehydrogenase (oxidase) 1a
chr8_+_13389115 0.26 ENSDART00000184428
ENSDART00000154266
ENSDART00000049469
jak3
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
chr9_+_14010823 0.25 ENSDART00000143837
si:ch211-67e16.3
si:ch211-67e16.3
chr13_+_35637875 0.25 ENSDART00000180657
thbs2a
thrombospondin 2a
chr10_-_43928937 0.23 ENSDART00000168014
ENSDART00000086220
mctp1b
multiple C2 domains, transmembrane 1b
chr2_-_16224083 0.23 ENSDART00000165953
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr20_+_53474963 0.23 ENSDART00000138976
bub1ba
BUB1 mitotic checkpoint serine/threonine kinase Ba
chr8_+_43053519 0.23 ENSDART00000147178
prnpa
prion protein a
chr15_+_17446796 0.22 ENSDART00000157189
snx19b
sorting nexin 19b
chr4_+_33654247 0.21 ENSDART00000192537
si:dkey-84h14.1
si:dkey-84h14.1
chr3_+_30968176 0.21 ENSDART00000186266
prf1.9
perforin 1.9
chr14_-_17588345 0.21 ENSDART00000143486
selenot2
selenoprotein T, 2
chr20_+_20726231 0.20 ENSDART00000147112
zgc:193541
zgc:193541
chr17_-_6536466 0.20 ENSDART00000188735
cenpo
centromere protein O
chr14_-_32884138 0.20 ENSDART00000105726
slc25a5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr20_-_34127415 0.19 ENSDART00000010028
ptgs2b
prostaglandin-endoperoxide synthase 2b
chr20_+_23390984 0.19 ENSDART00000136922
fryl
furry homolog, like
chr4_-_30057608 0.19 ENSDART00000184429
si:rp71-7l19.2
si:rp71-7l19.2
chr14_-_976912 0.18 ENSDART00000114053
arsia
arylsulfatase family, member Ia
chr13_+_35339182 0.18 ENSDART00000019323
jag1b
jagged 1b
chr4_+_76957765 0.18 ENSDART00000129607
si:dkey-240n22.6
si:dkey-240n22.6
chr8_+_27807974 0.18 ENSDART00000078509
capza1b
capping protein (actin filament) muscle Z-line, alpha 1b
chr15_-_29586747 0.18 ENSDART00000076749
samsn1a
SAM domain, SH3 domain and nuclear localisation signals 1a
chr5_+_1911814 0.18 ENSDART00000172233
si:ch73-55i23.1
si:ch73-55i23.1
chr13_+_24280380 0.17 ENSDART00000184115
acta1b
actin, alpha 1b, skeletal muscle
chr10_-_26738209 0.17 ENSDART00000188590
fgf13b
fibroblast growth factor 13b
chr19_-_5669122 0.17 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr12_+_48390715 0.17 ENSDART00000149351
scd
stearoyl-CoA desaturase (delta-9-desaturase)
chr22_-_29336268 0.16 ENSDART00000132776
ENSDART00000186351
ENSDART00000121599
pdgfba
platelet-derived growth factor beta polypeptide a
chr24_+_17260329 0.16 ENSDART00000129554
bmi1a
bmi1 polycomb ring finger oncogene 1a
chr8_+_36554816 0.15 ENSDART00000126687
sf3a1
splicing factor 3a, subunit 1
chr20_-_29418620 0.15 ENSDART00000172634
ryr3
ryanodine receptor 3
chr21_-_19906388 0.15 ENSDART00000114969
mfhas1
malignant fibrous histiocytoma amplified sequence 1
chr5_-_24270989 0.15 ENSDART00000146251
si:ch211-137i24.12
si:ch211-137i24.12
chr10_+_24643079 0.15 ENSDART00000139641
ENSDART00000142617
vps36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr12_-_25294096 0.14 ENSDART00000183398
hcar1-4
hydroxycarboxylic acid receptor 1-4
chr8_-_40276035 0.13 ENSDART00000185301
ENSDART00000187610
ENSDART00000053158
ENSDART00000162020
kdm2ba
lysine (K)-specific demethylase 2Ba
chr19_+_33093577 0.13 ENSDART00000180317
fam91a1
family with sequence similarity 91, member A1
chr10_+_26901222 0.13 ENSDART00000188766
ehbp1l1b
EH domain binding protein 1-like 1b
chr4_+_42175261 0.13 ENSDART00000162193
si:ch211-142b24.2
si:ch211-142b24.2
chr4_-_64605318 0.12 ENSDART00000170391
znf1099
zinc finger protein 1099
chr17_+_24623561 0.12 ENSDART00000156734
thumpd2
THUMP domain containing 2
chr14_+_30774894 0.12 ENSDART00000023054
atl3
atlastin 3
chr13_-_12602920 0.12 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr18_+_24921587 0.12 ENSDART00000191345
rgma
repulsive guidance molecule family member a
chr5_+_54585431 0.12 ENSDART00000171225
npr2
natriuretic peptide receptor 2
chr25_+_20119466 0.12 ENSDART00000104304
bpgm
2,3-bisphosphoglycerate mutase
chr7_-_6357952 0.11 ENSDART00000173197
zgc:165555
zgc:165555
chr1_-_35694978 0.11 ENSDART00000136157
si:dkey-27h10.2
si:dkey-27h10.2
chr3_-_21402279 0.11 ENSDART00000164513
CT573446.1

chr1_-_43897831 0.11 ENSDART00000048225
si:dkey-22i16.2
si:dkey-22i16.2
chr9_-_24244383 0.10 ENSDART00000182407
cavin2a
caveolae associated protein 2a
chr6_-_16561536 0.10 ENSDART00000167295
unc80
unc-80 homolog (C. elegans)
chr4_+_1530287 0.10 ENSDART00000067446
slc38a4
solute carrier family 38, member 4
chr13_+_8987957 0.10 ENSDART00000148144
hcar1-3
hydroxycarboxylic acid receptor 1-3
chr19_-_21716593 0.10 ENSDART00000155126
znf516
zinc finger protein 516
chr3_-_4760384 0.10 ENSDART00000108810
CABZ01046997.1

Network of associatons between targets according to the STRING database.

First level regulatory network of jund_batf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
1.0 4.0 GO:0060546 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.7 2.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.6 5.1 GO:0008343 adult feeding behavior(GO:0008343)
0.6 1.7 GO:0033335 anal fin development(GO:0033335)
0.5 4.4 GO:0003352 regulation of cilium movement(GO:0003352)
0.3 1.0 GO:0010935 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.3 2.6 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 1.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.2 0.7 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.2 1.0 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 0.7 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 1.4 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.8 GO:0060420 regulation of heart growth(GO:0060420)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 1.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 1.8 GO:0006825 copper ion transport(GO:0006825)
0.1 3.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.8 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.7 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 1.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 4.9 GO:0030048 actin filament-based movement(GO:0030048)
0.1 0.4 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.1 0.6 GO:0046661 male sex differentiation(GO:0046661)
0.1 0.3 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.6 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177)
0.0 0.2 GO:0015860 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 1.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.0 GO:0009749 response to glucose(GO:0009749)
0.0 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 1.3 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 3.0 GO:0007596 blood coagulation(GO:0007596)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.8 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.4 GO:0036353 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.0 10.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 1.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.2 GO:0006956 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.0 2.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.3 2.8 GO:0008180 COP9 signalosome(GO:0008180)
0.2 4.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.2 0.8 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.9 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.0 GO:0042627 chylomicron(GO:0042627)
0.1 0.7 GO:0032021 NELF complex(GO:0032021)
0.1 1.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.4 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 1.0 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 4.0 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.2 2.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 5.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.6 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 1.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 1.7 GO:0033691 sialic acid binding(GO:0033691)
0.1 3.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0043295 glutathione binding(GO:0043295)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 1.0 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.6 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 4.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 3.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.5 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 3.3 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 3.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 1.8 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 1.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME OPSINS Genes involved in Opsins