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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for klf12a

Z-value: 0.46

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Transcription factors associated with klf12a

Gene Symbol Gene ID Gene Info
klf12a
ENSDARG00000015312 Kruppel-like factor 12a
klf12a
ENSDARG00000115152 Kruppel-like factor 12a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12adr11_v1_chr1_+_34527213_34527213-0.233.5e-01Click!

Activity profile of klf12a motif

Sorted Z-values of klf12a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_17197546 2.10 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
gapdh
glyceraldehyde-3-phosphate dehydrogenase
chr7_+_1473929 1.50 ENSDART00000050687
lpcat4
lysophosphatidylcholine acyltransferase 4
chr17_-_18898115 1.46 ENSDART00000028044
galcb
galactosylceramidase b
chr12_+_46634736 1.43 ENSDART00000008009
trim16
tripartite motif containing 16
chr22_+_835728 1.40 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr8_-_32385989 1.35 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr13_-_6252498 1.31 ENSDART00000115157
tuba4l
tubulin, alpha 4 like
chr10_-_34002185 1.25 ENSDART00000046599
zar1l
zygote arrest 1-like
chr8_-_410728 1.25 ENSDART00000151255
trim36
tripartite motif containing 36
chr2_+_59015878 1.06 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
si:ch1073-391i24.1
chr5_-_69482891 1.06 ENSDART00000109487
CABZ01032476.1

chr23_-_31645760 1.05 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr20_-_182841 0.96 ENSDART00000064546
si:ch211-241j12.3
si:ch211-241j12.3
chr11_-_34577034 0.93 ENSDART00000133302
ENSDART00000184367
pfkfb4a
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr7_-_59159253 0.92 ENSDART00000159285
haus6
HAUS augmin-like complex, subunit 6
chr19_+_46113828 0.91 ENSDART00000159331
ENSDART00000161826
rbm24a
RNA binding motif protein 24a
chr9_+_8380728 0.91 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr21_-_13856689 0.88 ENSDART00000102197
fam129ba
family with sequence similarity 129, member Ba
chr1_+_45707219 0.87 ENSDART00000143363
si:ch211-214c7.4
si:ch211-214c7.4
chr17_+_17804752 0.86 ENSDART00000123350
sptlc2a
serine palmitoyltransferase, long chain base subunit 2a
chr3_-_40054615 0.84 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
llgl1
lethal giant larvae homolog 1 (Drosophila)
chr20_-_4031475 0.83 ENSDART00000112053
fam89a
family with sequence similarity 89, member A
chr21_+_34167178 0.81 ENSDART00000158308
trpc5b
transient receptor potential cation channel, subfamily C, member 5b
chr8_+_47219107 0.81 ENSDART00000146018
ENSDART00000075068
mthfr
methylenetetrahydrofolate reductase (NAD(P)H)
chr24_-_11076400 0.80 ENSDART00000003195
chmp4c
charged multivesicular body protein 4C
chr4_-_4612116 0.78 ENSDART00000130601
CABZ01020840.1
Danio rerio apoptosis facilitator Bcl-2-like protein 14 (LOC101885512), mRNA.
chr14_+_7048930 0.77 ENSDART00000109138
hbegfa
heparin-binding EGF-like growth factor a
chr11_+_45287541 0.76 ENSDART00000165321
ENSDART00000173116
pycr1b
pyrroline-5-carboxylate reductase 1b
chr10_-_44017642 0.72 ENSDART00000135240
ENSDART00000014669
acads
acyl-CoA dehydrogenase short chain
chr2_-_32513538 0.72 ENSDART00000056640
abcf2a
ATP-binding cassette, sub-family F (GCN20), member 2a
chr16_-_17713859 0.70 ENSDART00000149275
zgc:174935
zgc:174935
chr5_-_9824908 0.67 ENSDART00000169698
zgc:158343
zgc:158343
chr23_+_30730121 0.64 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr22_+_24623936 0.63 ENSDART00000160924
mcoln2
mucolipin 2
chr5_+_36850650 0.62 ENSDART00000051186
nccrp1
non-specific cytotoxic cell receptor protein 1
chr24_-_36238054 0.62 ENSDART00000155725
tmem241
transmembrane protein 241
chr7_+_55292959 0.62 ENSDART00000147539
ENSDART00000073555
ctu2
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr16_+_30002605 0.58 ENSDART00000160555
sema6e
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr7_+_38349667 0.58 ENSDART00000010046
rhpn2
rhophilin, Rho GTPase binding protein 2
chr25_+_7492663 0.58 ENSDART00000166496
cat
catalase
chr15_+_29025090 0.57 ENSDART00000131755
si:ch211-137a8.2
si:ch211-137a8.2
chr17_+_16429826 0.57 ENSDART00000136078
efcab11
EF-hand calcium binding domain 11
chr7_-_19364813 0.57 ENSDART00000173977
ntn4
netrin 4
chr5_-_23696926 0.57 ENSDART00000021462
rnf128a
ring finger protein 128a
chr6_+_41503854 0.57 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cish
cytokine inducible SH2-containing protein
chr14_-_24110707 0.56 ENSDART00000133522
ENSDART00000123152
cpeb4a
cytoplasmic polyadenylation element binding protein 4a
chr8_+_104114 0.56 ENSDART00000172101
sncaip
synuclein, alpha interacting protein
chr20_-_15104709 0.56 ENSDART00000034011
fmo5
flavin containing monooxygenase 5
chr16_+_43077909 0.55 ENSDART00000014140
rundc3b
RUN domain containing 3b
chr2_+_25658112 0.54 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr22_-_20924747 0.54 ENSDART00000185845
ENSDART00000179672
ell
elongation factor RNA polymerase II
chr3_-_32362872 0.54 ENSDART00000035545
ENSDART00000012630
prmt1
protein arginine methyltransferase 1
chr13_+_42309688 0.53 ENSDART00000158367
ide
insulin-degrading enzyme
chr22_-_20924564 0.53 ENSDART00000100642
ENSDART00000032770
ell
elongation factor RNA polymerase II
chr25_+_186583 0.53 ENSDART00000161504
pclaf
PCNA clamp associated factor
chr11_+_13524504 0.52 ENSDART00000139889
arrdc2
arrestin domain containing 2
chr17_+_35097024 0.51 ENSDART00000026152
asap2a
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr15_+_28410664 0.50 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr5_-_36597612 0.50 ENSDART00000031270
ENSDART00000122098
rhogc
ras homolog gene family, member Gc
chr21_-_22122312 0.49 ENSDART00000101726
slc35f2
solute carrier family 35, member F2
chr21_+_1647990 0.48 ENSDART00000148540
fech
ferrochelatase
chr6_-_40657653 0.48 ENSDART00000154359
ppil1
peptidylprolyl isomerase (cyclophilin)-like 1
chr8_-_410199 0.47 ENSDART00000091177
ENSDART00000122979
ENSDART00000151331
ENSDART00000151155
trim36
tripartite motif containing 36
chr6_-_7776612 0.47 ENSDART00000190269
myh9a
myosin, heavy chain 9a, non-muscle
chr18_+_38191346 0.46 ENSDART00000052703
nucb2b
nucleobindin 2b
chr25_+_6122823 0.43 ENSDART00000191824
ENSDART00000067514
rbpms2a
RNA binding protein with multiple splicing 2a
chr2_-_39675829 0.43 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr5_-_12031174 0.43 ENSDART00000159896
castor1
cytosolic arginine sensor for mTORC1 subunit 1
chr17_-_24889837 0.43 ENSDART00000187980
gale
UDP-galactose-4-epimerase
chr10_+_1052591 0.42 ENSDART00000123405
unc5c
unc-5 netrin receptor C
chr21_-_32060993 0.42 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr21_+_21279159 0.42 ENSDART00000148346
itpkca
inositol-trisphosphate 3-kinase Ca
chr16_-_7793457 0.41 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr3_-_31924643 0.41 ENSDART00000122589
rnf113a
ring finger protein 113A
chr7_+_55518519 0.41 ENSDART00000098476
ENSDART00000149915
cdt1
chromatin licensing and DNA replication factor 1
chr6_+_7533601 0.41 ENSDART00000057823
pa2g4a
proliferation-associated 2G4, a
chr3_-_32541033 0.40 ENSDART00000151476
ENSDART00000055324
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr3_+_32410746 0.40 ENSDART00000025496
rras
RAS related
chr21_+_22330005 0.40 ENSDART00000140751
ENSDART00000157839
ENSDART00000140468
nadk2
NAD kinase 2, mitochondrial
chr24_-_26632171 0.40 ENSDART00000008374
ENSDART00000017384
tnikb
TRAF2 and NCK interacting kinase b
chr15_-_19128705 0.40 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr4_+_9011448 0.40 ENSDART00000192357
samm50l
sorting and assembly machinery component 50 homolog, like
chr5_+_43458304 0.40 ENSDART00000051114
rhobtb2a
Rho-related BTB domain containing 2a
chr15_-_1001177 0.40 ENSDART00000160730
zgc:162936
zgc:162936
chr22_+_5118361 0.39 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr8_-_4618653 0.39 ENSDART00000025535
sept5a
septin 5a
chr25_+_3788443 0.39 ENSDART00000189747
chid1
chitinase domain containing 1
chr17_+_44441042 0.38 ENSDART00000142123
ap5m1
adaptor-related protein complex 5, mu 1 subunit
chr11_+_5499661 0.38 ENSDART00000027850
slc35e1
solute carrier family 35, member E1
chr9_+_50110763 0.38 ENSDART00000162990
cobll1b
cordon-bleu WH2 repeat protein-like 1b
chr2_+_35880600 0.37 ENSDART00000004277
lamc1
laminin, gamma 1
chr20_-_51656512 0.37 ENSDART00000129965
LO018154.1

chr17_+_25332711 0.37 ENSDART00000082319
tmem54a
transmembrane protein 54a
chr2_+_25657958 0.36 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr20_-_25748407 0.36 ENSDART00000063152
chst14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr10_-_41352502 0.36 ENSDART00000052971
ENSDART00000128156
rab11fip1b
RAB11 family interacting protein 1 (class I) b
chr2_+_25560556 0.36 ENSDART00000133623
pld1a
phospholipase D1a
chr4_+_9011825 0.36 ENSDART00000058007
samm50l
sorting and assembly machinery component 50 homolog, like
chr9_+_30421489 0.34 ENSDART00000145025
ENSDART00000132058
zgc:113314
zgc:113314
chr20_+_35058634 0.34 ENSDART00000122696
hnrnpub
heterogeneous nuclear ribonucleoprotein Ub
chr5_+_4006837 0.34 ENSDART00000138862
pigw
phosphatidylinositol glycan anchor biosynthesis, class W
chr2_+_11028923 0.34 ENSDART00000076725
acot11a
acyl-CoA thioesterase 11a
chr23_-_18707418 0.34 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
zgc:103759
chr16_-_26132122 0.33 ENSDART00000157787
lipeb
lipase, hormone-sensitive b
chr2_+_43894368 0.33 ENSDART00000143885
gbp3
guanylate binding protein 3
chr22_-_21676364 0.33 ENSDART00000183668
tle2b
transducin like enhancer of split 2b
chr13_+_28618086 0.33 ENSDART00000087001
cnnm2a
cyclin and CBS domain divalent metal cation transport mediator 2a
chr8_-_1698155 0.32 ENSDART00000186159
CABZ01065417.1

chr23_-_27822920 0.32 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr7_+_40083601 0.32 ENSDART00000099046
zgc:112356
zgc:112356
chr3_+_15893039 0.32 ENSDART00000055780
jpt2
Jupiter microtubule associated homolog 2
chr6_-_25165693 0.32 ENSDART00000167259
znf326
zinc finger protein 326
chr1_+_1712140 0.31 ENSDART00000081047
atp1a1a.1
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 1
chr1_-_8653385 0.31 ENSDART00000193041
actb1
actin, beta 1
chr5_+_61658282 0.31 ENSDART00000188878
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr20_-_13140309 0.31 ENSDART00000020703
ENSDART00000188594
ints7
integrator complex subunit 7
chr23_-_10745288 0.31 ENSDART00000140745
ENSDART00000013768
eif4e3
eukaryotic translation initiation factor 4E family member 3
chr3_-_52899394 0.30 ENSDART00000128223
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr6_-_1591002 0.30 ENSDART00000087039
zgc:123305
zgc:123305
chr13_+_421231 0.30 ENSDART00000188212
ENSDART00000017854
lgi1a
leucine-rich, glioma inactivated 1a
chr21_-_11657043 0.30 ENSDART00000141297
cast
calpastatin
chr10_+_29204581 0.29 ENSDART00000148503
picalma
phosphatidylinositol binding clathrin assembly protein a
chr17_-_44440832 0.29 ENSDART00000148786
exoc5
exocyst complex component 5
chr18_+_6558338 0.29 ENSDART00000110892
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr13_-_42673978 0.29 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
lrrfip2
leucine rich repeat (in FLII) interacting protein 2
chr12_-_48312647 0.29 ENSDART00000114415
ascc1
activating signal cointegrator 1 complex subunit 1
chr16_+_53455638 0.29 ENSDART00000045792
ENSDART00000154189
rbm24b
RNA binding motif protein 24b
chr10_+_37500234 0.28 ENSDART00000132096
ENSDART00000099473
msi2a
musashi RNA-binding protein 2a
chr19_-_31686252 0.28 ENSDART00000131721
ripor2
RHO family interacting cell polarization regulator 2
chr5_+_61657702 0.28 ENSDART00000134387
ENSDART00000171248
ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr18_+_6558146 0.28 ENSDART00000169401
b4galnt3b
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr16_+_19637384 0.27 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr7_+_29044888 0.27 ENSDART00000086871
gfod2
glucose-fructose oxidoreductase domain containing 2
chr16_-_31351419 0.27 ENSDART00000178298
ENSDART00000018091
mroh1
maestro heat-like repeat family member 1
chr25_+_35375848 0.27 ENSDART00000155721
ano3
anoctamin 3
chr23_-_5818992 0.27 ENSDART00000148730
csrp1a
cysteine and glycine-rich protein 1a
chr3_-_40276057 0.26 ENSDART00000132225
ENSDART00000074737
shmt1
serine hydroxymethyltransferase 1 (soluble)
chr20_+_29565906 0.26 ENSDART00000062383
ywhaqa
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
chr10_+_6383270 0.26 ENSDART00000170548
zgc:114200
zgc:114200
chr6_+_23122789 0.26 ENSDART00000049226
ENSDART00000067560
acox1
acyl-CoA oxidase 1, palmitoyl
chr6_+_18520859 0.26 ENSDART00000158263
si:dkey-10p5.10
si:dkey-10p5.10
chr17_-_51260476 0.26 ENSDART00000084348
trappc12
trafficking protein particle complex 12
chr24_-_38644937 0.26 ENSDART00000170194
slc6a16b
solute carrier family 6, member 16b
chr15_-_19443997 0.26 ENSDART00000114936
esamb
endothelial cell adhesion molecule b
chr22_-_3172823 0.25 ENSDART00000167550
lonp1
lon peptidase 1, mitochondrial
chr23_-_19831739 0.25 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr8_+_47099033 0.25 ENSDART00000142979
arhgef16
Rho guanine nucleotide exchange factor (GEF) 16
chr23_-_3759345 0.25 ENSDART00000132205
ENSDART00000137707
ENSDART00000189382
hmga1a
high mobility group AT-hook 1a
chr15_-_9593532 0.25 ENSDART00000169912
gab2
GRB2-associated binding protein 2
chr16_+_26747766 0.24 ENSDART00000183257
rad54b
RAD54 homolog B (S. cerevisiae)
chr22_-_38224315 0.24 ENSDART00000165430
ENSDART00000140968
hps3
Hermansky-Pudlak syndrome 3
chr14_+_31566517 0.24 ENSDART00000002684
ints6l
integrator complex subunit 6 like
chr18_-_7481036 0.24 ENSDART00000101292
si:dkey-238c7.16
si:dkey-238c7.16
chr2_+_58221163 0.24 ENSDART00000157939
FO704813.1

chr20_+_1196386 0.24 ENSDART00000041192
lyrm2
LYR motif containing 2
chr1_+_53714734 0.23 ENSDART00000114689
pus10
pseudouridylate synthase 10
chr1_-_493218 0.23 ENSDART00000031635
ercc5
excision repair cross-complementation group 5
chr25_-_6049339 0.23 ENSDART00000075184
snx1a
sorting nexin 1a
chr3_+_19685873 0.23 ENSDART00000006490
tlk2
tousled-like kinase 2
chr19_+_8144556 0.23 ENSDART00000027274
ENSDART00000147218
efna3a
ephrin-A3a
chr5_+_68807170 0.23 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr5_-_43819663 0.23 ENSDART00000022481
mccc2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr3_-_50998577 0.23 ENSDART00000157735
cdc42ep4a
CDC42 effector protein (Rho GTPase binding) 4a
chr17_+_6765621 0.22 ENSDART00000156637
ENSDART00000007622
afg1la
AFG1 like ATPase a
chr10_+_33382858 0.22 ENSDART00000063662
mdh2
malate dehydrogenase 2, NAD (mitochondrial)
chr19_-_34011340 0.22 ENSDART00000172618
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr13_-_44808783 0.22 ENSDART00000099984
glo1
glyoxalase 1
chr18_+_20047374 0.22 ENSDART00000146957
uacaa
uveal autoantigen with coiled-coil domains and ankyrin repeats a
chr1_-_55058795 0.21 ENSDART00000187293
peli1a
pellino E3 ubiquitin protein ligase 1a
chr16_-_280835 0.21 ENSDART00000190541
LO017917.1

chr1_-_55210619 0.21 ENSDART00000111671
mri1
methylthioribose-1-phosphate isomerase 1
chr11_-_25384213 0.20 ENSDART00000103650
mafbb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
chr25_+_4635355 0.20 ENSDART00000021120
pgghg
protein-glucosylgalactosylhydroxylysine glucosidase
chr15_-_5580093 0.20 ENSDART00000143726
wdr62
WD repeat domain 62
chr18_+_27077853 0.20 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
ppp1r15b
protein phosphatase 1, regulatory subunit 15B
chr1_+_45922699 0.20 ENSDART00000033669
lipt1
lipoyltransferase 1
chr13_-_33671694 0.20 ENSDART00000143945
ENSDART00000100504
zgc:163030
zgc:163030
chr25_-_37284370 0.19 ENSDART00000103222
nudt7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr21_-_5056812 0.18 ENSDART00000139713
ENSDART00000140859
zgc:77838
zgc:77838
chr14_-_24277805 0.18 ENSDART00000054243
dpf2l
D4, zinc and double PHD fingers family 2, like
chr11_+_3005536 0.18 ENSDART00000174539
cpne5b
copine Vb
chr19_-_2421793 0.18 ENSDART00000180238
TMEM196 (1 of many)
transmembrane protein 196
chr21_-_14692119 0.18 ENSDART00000123047
ehmt1b
euchromatic histone-lysine N-methyltransferase 1b
chr3_+_17951790 0.17 ENSDART00000164663
aclya
ATP citrate lyase a
chr24_-_20152965 0.17 ENSDART00000147004
oxsr1b
oxidative stress responsive 1b
chr17_-_25831569 0.17 ENSDART00000148743
hhat
hedgehog acyltransferase
chr19_+_29854223 0.17 ENSDART00000109729
ENSDART00000157419
si:ch73-130a3.4
si:ch73-130a3.4
chr3_+_22984098 0.17 ENSDART00000043190
lsm12a
LSM12 homolog a
chr7_-_73815262 0.16 ENSDART00000185351
zgc:165555
zgc:165555
chr8_+_20157798 0.16 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr19_+_7154500 0.16 ENSDART00000035967
ENSDART00000160894
brd2a
bromodomain containing 2a
chr22_-_2922053 0.16 ENSDART00000178290
pak2b
p21 protein (Cdc42/Rac)-activated kinase 2b
chr13_-_36621926 0.16 ENSDART00000057155
cdkn3
cyclin-dependent kinase inhibitor 3
chr23_-_17429775 0.16 ENSDART00000043076
ppdpfb
pancreatic progenitor cell differentiation and proliferation factor b
chr9_-_3149896 0.16 ENSDART00000020861
pdk1
pyruvate dehydrogenase kinase, isozyme 1
chr23_-_3759692 0.15 ENSDART00000028885
hmga1a
high mobility group AT-hook 1a
chr5_+_23136544 0.15 ENSDART00000003428
ENSDART00000109340
ENSDART00000171039
ENSDART00000178821
prps1a
phosphoribosyl pyrophosphate synthetase 1A
chr25_+_19008497 0.15 ENSDART00000104420
samm50
SAMM50 sorting and assembly machinery component
chr11_-_40647190 0.15 ENSDART00000173217
ENSDART00000173276
ENSDART00000147264
fam213b
family with sequence similarity 213, member B
chr14_+_33264303 0.15 ENSDART00000130680
ENSDART00000075187
pdzd11
PDZ domain containing 11

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:2001014 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 0.9 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.2 1.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.2 0.7 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 1.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.5 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.6 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.3 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.3 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.5 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.4 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.4 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.8 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 0.4 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.3 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 0.8 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:0002931 response to ischemia(GO:0002931)
0.1 0.9 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.8 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.8 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.7 GO:0016074 snoRNA metabolic process(GO:0016074)
0.1 0.4 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1 2.1 GO:0050821 protein stabilization(GO:0050821)
0.1 0.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 0.5 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.7 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.5 GO:0032094 response to food(GO:0032094)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0001709 cell fate determination(GO:0001709)
0.0 0.6 GO:0046688 response to copper ion(GO:0046688)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0031268 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.7 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.4 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0061055 myotome development(GO:0061055)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 0.1 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.5 GO:0043249 heme biosynthetic process(GO:0006783) erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 1.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.0 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.2 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 1.3 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 0.9 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.6 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:0044609 DBIRD complex(GO:0044609)
0.1 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0097433 dense body(GO:0097433)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.1 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.3 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.3 0.9 GO:1990715 mRNA CDS binding(GO:1990715)
0.2 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0034618 arginine binding(GO:0034618)
0.1 0.4 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.6 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.1 0.3 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.3 GO:0043621 protein self-association(GO:0043621)
0.1 0.3 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.5 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.6 GO:0004096 catalase activity(GO:0004096)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.8 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.5 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.4 GO:0008061 chitin binding(GO:0008061)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 1.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.6 PID FOXO PATHWAY FoxO family signaling
0.0 2.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 1.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex