Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for lef1

Z-value: 1.32

Motif logo

logo of

Transcription factors associated with lef1

Gene Symbol Gene ID Gene Info
lef1
ENSDARG00000031894 lymphoid enhancer-binding factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lef1dr11_v1_chr1_+_49814942_498149420.911.6e-07Click!

Activity profile of lef1 motif

Sorted Z-values of lef1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_10175898 5.02 ENSDART00000146185
krt5
keratin 5
chr1_+_44173245 3.80 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
ctnnd1
catenin (cadherin-associated protein), delta 1
chr3_-_55650771 3.44 ENSDART00000162413
axin2
axin 2 (conductin, axil)
chr20_-_29498178 3.35 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
rrm2
ribonucleotide reductase M2 polypeptide
chr1_+_44173506 3.09 ENSDART00000170512
ctnnd1
catenin (cadherin-associated protein), delta 1
chr11_-_26832685 2.52 ENSDART00000153519
iqsec1b
IQ motif and Sec7 domain 1b
chr5_-_28149767 2.49 ENSDART00000051515
zgc:110329
zgc:110329
chr1_+_36772348 2.39 ENSDART00000109314
arhgap10
Rho GTPase activating protein 10
chr12_+_48340133 2.34 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
ddit4
DNA-damage-inducible transcript 4
chr19_+_43523690 2.32 ENSDART00000113031
wasf2
WAS protein family, member 2
chr7_-_24112484 2.24 ENSDART00000111923
ajuba
ajuba LIM protein
chr2_+_35603637 2.11 ENSDART00000147278
plk3
polo-like kinase 3 (Drosophila)
chr15_-_25099679 2.09 ENSDART00000154628
rflnb
refilin B
chr8_+_13106760 1.99 ENSDART00000029308
itgb4
integrin, beta 4
chr7_+_17947217 1.90 ENSDART00000101601
cth1
cysteine three histidine 1
chr8_-_9570511 1.89 ENSDART00000044000
plxna3
plexin A3
chr3_-_55650417 1.85 ENSDART00000171441
axin2
axin 2 (conductin, axil)
chr21_-_30082414 1.84 ENSDART00000157307
ENSDART00000155188
ccnjl
cyclin J-like
chr17_-_4245311 1.84 ENSDART00000055379
gdf3
growth differentiation factor 3
chr20_-_3319642 1.83 ENSDART00000186743
ENSDART00000123096
marcksa
myristoylated alanine-rich protein kinase C substrate a
chr2_-_49031303 1.83 ENSDART00000143471
cdc34b
cell division cycle 34 homolog (S. cerevisiae) b
chr17_-_26507289 1.82 ENSDART00000155616
ccser2a
coiled-coil serine-rich protein 2a
chr21_-_18275226 1.77 ENSDART00000126672
ENSDART00000135239
brd3a
bromodomain containing 3a
chr11_+_31609481 1.74 ENSDART00000124830
ENSDART00000162768
zgc:162816
zgc:162816
chr14_+_15155684 1.74 ENSDART00000167966
zgc:158852
zgc:158852
chr21_-_13690712 1.73 ENSDART00000065817
pou5f3
POU domain, class 5, transcription factor 3
chr5_+_57924611 1.71 ENSDART00000050949
btg4
B-cell translocation gene 4
chr6_-_33913184 1.71 ENSDART00000146373
nasp
nuclear autoantigenic sperm protein (histone-binding)
chr2_-_51087077 1.70 ENSDART00000167987
ftr67
finTRIM family, member 67
chr16_-_34195002 1.70 ENSDART00000054026
rcc1
regulator of chromosome condensation 1
chr5_+_44846280 1.65 ENSDART00000084370
kank1a
KN motif and ankyrin repeat domains 1a
chr7_+_10701938 1.63 ENSDART00000158162
arnt2
aryl-hydrocarbon receptor nuclear translocator 2
chr19_-_29302249 1.62 ENSDART00000188751
srfbp1
serum response factor binding protein 1
chr17_-_31483469 1.60 ENSDART00000062907
ENSDART00000061547
ltk
leukocyte receptor tyrosine kinase
chr12_+_38774860 1.58 ENSDART00000130371
kif19
kinesin family member 19
chr15_-_31177324 1.57 ENSDART00000008854
wsb1
WD repeat and SOCS box containing 1
chr13_+_31716820 1.56 ENSDART00000034745
prkcha
protein kinase C, eta, a
chr8_+_30742898 1.56 ENSDART00000018475
snrpd3
small nuclear ribonucleoprotein D3 polypeptide
chr7_+_40081630 1.53 ENSDART00000173559
zgc:112356
zgc:112356
chr7_+_71955486 1.53 ENSDART00000189349
CABZ01071171.1
Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA.
chr7_-_6754012 1.52 ENSDART00000113658
zgc:55262
zgc:55262
chr22_-_10541712 1.52 ENSDART00000013933
si:dkey-42i9.4
si:dkey-42i9.4
chr23_-_36449111 1.52 ENSDART00000110478
zgc:174906
zgc:174906
chr14_+_6963312 1.49 ENSDART00000150050
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr17_-_12498096 1.48 ENSDART00000149551
ENSDART00000105215
ENSDART00000191207
emilin1b
elastin microfibril interfacer 1b
chr17_-_7218481 1.47 ENSDART00000181967
SAMD5
sterile alpha motif domain containing 5
chr21_-_20321660 1.46 ENSDART00000188497
zgc:86764
zgc:86764
chr14_+_6962271 1.46 ENSDART00000148447
ENSDART00000149114
ENSDART00000149492
ENSDART00000148394
hnrnpaba
heterogeneous nuclear ribonucleoprotein A/Ba
chr18_+_14307059 1.45 ENSDART00000186558
zgc:173742
zgc:173742
chr12_+_35203091 1.45 ENSDART00000153022
ndst2b
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b
chr23_-_27822920 1.44 ENSDART00000023094
acvr1ba
activin A receptor type 1Ba
chr7_-_26270014 1.43 ENSDART00000079347
serpine1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr21_+_34119759 1.42 ENSDART00000024750
ENSDART00000128242
hmgb3b
high mobility group box 3b
chr17_+_15535501 1.41 ENSDART00000002932
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr8_-_19467011 1.41 ENSDART00000162010
zgc:92140
zgc:92140
chr17_-_4245902 1.40 ENSDART00000151851
gdf3
growth differentiation factor 3
chr7_+_59677273 1.40 ENSDART00000039535
ENSDART00000132044
trmt44
tRNA methyltransferase 44 homolog
chr8_+_7854130 1.39 ENSDART00000165575
cxxc1a
CXXC finger protein 1a
chr1_-_52790724 1.37 ENSDART00000139577
ENSDART00000100937
patl1
protein associated with topoisomerase II homolog 1 (yeast)
chr6_+_23810529 1.36 ENSDART00000166921
glulb
glutamate-ammonia ligase (glutamine synthase) b
chr6_+_296130 1.36 ENSDART00000073985
rbfox2
RNA binding fox-1 homolog 2
chr12_+_27231607 1.34 ENSDART00000066270
tmem106a
transmembrane protein 106A
chr1_-_23293261 1.34 ENSDART00000122648
ugdh
UDP-glucose 6-dehydrogenase
chr9_-_12401871 1.33 ENSDART00000191901
nup35
nucleoporin 35
chr13_-_35808904 1.33 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr5_-_23596339 1.33 ENSDART00000024815
fam76b
family with sequence similarity 76, member B
chr1_-_36772147 1.32 ENSDART00000053369
prmt9
protein arginine methyltransferase 9
chr23_-_3758637 1.32 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
hmga1a
high mobility group AT-hook 1a
chr14_+_7699443 1.32 ENSDART00000123139
brd8
bromodomain containing 8
chr23_-_10745288 1.29 ENSDART00000140745
ENSDART00000013768
eif4e3
eukaryotic translation initiation factor 4E family member 3
chr11_-_2250767 1.29 ENSDART00000018131
hnrnpa1a
heterogeneous nuclear ribonucleoprotein A1a
chr12_+_46855036 1.28 ENSDART00000148670
adkb
adenosine kinase b
chr15_-_28587147 1.28 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr10_+_3153973 1.28 ENSDART00000183223
hic2
hypermethylated in cancer 2
chr10_+_17371356 1.27 ENSDART00000122663
sppl3
signal peptide peptidase 3
chr12_+_27231212 1.27 ENSDART00000133023
ENSDART00000123739
tmem106a
transmembrane protein 106A
chr11_-_23687158 1.27 ENSDART00000189599
pik3c2b
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr5_-_56964547 1.26 ENSDART00000074400
tia1
TIA1 cytotoxic granule-associated RNA binding protein
chr19_-_23249822 1.26 ENSDART00000140665
grb10a
growth factor receptor-bound protein 10a
chr1_+_36771954 1.25 ENSDART00000149022
arhgap10
Rho GTPase activating protein 10
chr9_-_39547907 1.23 ENSDART00000163635
erbb4b
erb-b2 receptor tyrosine kinase 4b
chr7_+_41887429 1.23 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr21_+_13387965 1.23 ENSDART00000134347
zgc:113162
zgc:113162
chr7_+_36467796 1.23 ENSDART00000146202
aktip
akt interacting protein
chr4_-_10826575 1.22 ENSDART00000164771
ENSDART00000067256
ppfibp1a
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr25_+_8921425 1.22 ENSDART00000128591
accs
1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
chr9_-_28990649 1.22 ENSDART00000078823
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr11_-_11792766 1.21 ENSDART00000011657
cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr1_+_49814461 1.21 ENSDART00000132405
lef1
lymphoid enhancer-binding factor 1
chr17_-_6613458 1.20 ENSDART00000175024
si:ch211-189e2.3
si:ch211-189e2.3
chr5_+_33301005 1.20 ENSDART00000006021
usp20
ubiquitin specific peptidase 20
chr20_-_48701593 1.20 ENSDART00000132835
pax1b
paired box 1b
chr21_-_37027252 1.20 ENSDART00000076483
zgc:77151
zgc:77151
chr22_-_10541372 1.20 ENSDART00000179708
si:dkey-42i9.4
si:dkey-42i9.4
chr14_-_21618005 1.20 ENSDART00000043162
reep2
receptor accessory protein 2
chr13_+_30506781 1.19 ENSDART00000110884
zmiz1a
zinc finger, MIZ-type containing 1a
chr22_+_21549419 1.19 ENSDART00000139411
plpp2b
phospholipid phosphatase 2b
chr2_+_25658112 1.19 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr8_+_30743263 1.18 ENSDART00000181234
p2rx4b
purinergic receptor P2X, ligand-gated ion channel, 4b
chr12_-_33354409 1.17 ENSDART00000178515
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr20_+_46040666 1.16 ENSDART00000060744
si:dkey-7c18.24
si:dkey-7c18.24
chr10_+_39199547 1.16 ENSDART00000075943
ei24
etoposide induced 2.4
chr2_-_37312927 1.16 ENSDART00000141214
skila
SKI-like proto-oncogene a
chr19_+_26072624 1.16 ENSDART00000147627
jarid2b
jumonji, AT rich interactive domain 2b
chr15_-_35930070 1.16 ENSDART00000076229
irs1
insulin receptor substrate 1
chr13_+_29925397 1.15 ENSDART00000123482
cuedc2
CUE domain containing 2
chr19_-_47570672 1.15 ENSDART00000112155
rrm2
ribonucleotide reductase M2 polypeptide
chr2_-_22152797 1.13 ENSDART00000145188
cyp7a1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr4_-_27117112 1.13 ENSDART00000034534
zbed4
zinc finger, BED-type containing 4
chr18_-_13133268 1.12 ENSDART00000081811
zgc:112052
zgc:112052
chr9_-_34507680 1.12 ENSDART00000113656
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr10_+_15608326 1.12 ENSDART00000188770
zfand5b
zinc finger, AN1-type domain 5b
chr13_-_45022527 1.12 ENSDART00000159021
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr15_-_26930999 1.11 ENSDART00000181674
ENSDART00000126046
ccdc9
coiled-coil domain containing 9
chr9_-_54840124 1.11 ENSDART00000137214
ENSDART00000085693
gpm6bb
glycoprotein M6Bb
chr5_-_22019061 1.10 ENSDART00000113066
amer1
APC membrane recruitment protein 1
chr20_-_33705044 1.09 ENSDART00000166573
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr7_+_66634167 1.09 ENSDART00000027616
eif4g2a
eukaryotic translation initiation factor 4, gamma 2a
chr17_+_44030692 1.09 ENSDART00000049503
peli2
pellino E3 ubiquitin protein ligase family member 2
chr19_-_20106486 1.09 ENSDART00000043924
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr9_+_34148714 1.08 ENSDART00000078051
gpr161
G protein-coupled receptor 161
chr9_-_20853439 1.08 ENSDART00000028247
ENSDART00000133321
gdap2
ganglioside induced differentiation associated protein 2
chr8_-_18899427 1.08 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr14_-_5642371 1.07 ENSDART00000183859
ENSDART00000054876
npm1b
nucleophosmin 1b
chr17_-_29312506 1.07 ENSDART00000133668
tecpr2
tectonin beta-propeller repeat containing 2
chr15_-_26931541 1.06 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr14_+_28492990 1.06 ENSDART00000160347
ENSDART00000187176
ENSDART00000088094
stag2b
stromal antigen 2b
chr20_+_23625387 1.06 ENSDART00000147945
ENSDART00000150497
palld
palladin, cytoskeletal associated protein
chr10_-_15879569 1.06 ENSDART00000136789
tjp2a
tight junction protein 2a (zona occludens 2)
chr2_+_9821757 1.06 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
anxa13l
annexin A13, like
chr8_-_22542467 1.05 ENSDART00000182588
ENSDART00000134542
csde1
cold shock domain containing E1, RNA-binding
chr11_-_43226255 1.05 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr2_+_25657958 1.05 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr2_+_32846602 1.04 ENSDART00000056649
tmem53
transmembrane protein 53
chr11_+_24313931 1.03 ENSDART00000017599
ENSDART00000166045
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr5_+_43470544 1.03 ENSDART00000111587
rhobtb2a
Rho-related BTB domain containing 2a
chr3_+_26245731 1.03 ENSDART00000103734
atad5a
ATPase family, AAA domain containing 5a
chr9_-_27410597 1.02 ENSDART00000135652
ENSDART00000042297
kdelc1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr19_-_11014641 1.02 ENSDART00000183745
tpm3
tropomyosin 3
chr14_+_25505468 1.01 ENSDART00000079016
thoc3
THO complex 3
chr6_+_6780873 1.01 ENSDART00000011865
sec23b
Sec23 homolog B, COPII coat complex component
chr14_-_33308138 1.01 ENSDART00000136442
ENSDART00000139615
sept6
septin 6
chr24_+_35911300 1.01 ENSDART00000129679
abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr7_+_20260172 1.00 ENSDART00000012450
dvl2
dishevelled segment polarity protein 2
chr13_-_45022301 1.00 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
khdrbs1a
KH domain containing, RNA binding, signal transduction associated 1a
chr9_+_33340311 1.00 ENSDART00000140064
ddx3a
DEAD (Asp-Glu-Ala-Asp) box helicase 3a
chr13_+_30421472 0.99 ENSDART00000143569
zmiz1a
zinc finger, MIZ-type containing 1a
chr3_-_18373425 0.99 ENSDART00000178522
spag9a
sperm associated antigen 9a
chr22_+_21618121 0.99 ENSDART00000133939
tle2a
transducin like enhancer of split 2a
chr3_-_23574622 0.98 ENSDART00000176012
igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr19_+_29337789 0.98 ENSDART00000021396
ldlrap1a
low density lipoprotein receptor adaptor protein 1a
chr11_-_12800945 0.98 ENSDART00000191178
txlng
taxilin gamma
chr11_-_12801157 0.98 ENSDART00000103449
txlng
taxilin gamma
chr5_+_15992655 0.97 ENSDART00000182148
znrf3
zinc and ring finger 3
chr3_-_60589292 0.97 ENSDART00000157822
jmjd6
jumonji domain containing 6
chr1_-_28950366 0.96 ENSDART00000110270
pwp2h
PWP2 periodic tryptophan protein homolog (yeast)
chr14_-_25930182 0.95 ENSDART00000018651
ENSDART00000147991
g3bp1
GTPase activating protein (SH3 domain) binding protein 1
chr9_-_34509997 0.95 ENSDART00000169114
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta
chr2_+_49805892 0.94 ENSDART00000056248
wdr48b
WD repeat domain 48b
chr17_-_29311835 0.94 ENSDART00000104224
tecpr2
tectonin beta-propeller repeat containing 2
chr15_+_40188076 0.94 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr17_+_35243753 0.94 ENSDART00000016702
iah1
isoamyl acetate hydrolyzing esterase 1 (putative)
chr17_-_21057617 0.94 ENSDART00000148095
ENSDART00000048853
ube2d1a
ubiquitin-conjugating enzyme E2D 1a
chr1_+_49814942 0.94 ENSDART00000164936
lef1
lymphoid enhancer-binding factor 1
chr5_+_6672870 0.93 ENSDART00000126598
pxna
paxillin a
chr8_-_25034411 0.93 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr8_-_12847483 0.93 ENSDART00000146186
si:dkey-104n9.1
si:dkey-104n9.1
chr11_+_24314148 0.93 ENSDART00000171491
rem1
RAS (RAD and GEM)-like GTP-binding 1
chr11_+_19068442 0.92 ENSDART00000171766
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr6_+_59832786 0.92 ENSDART00000154985
ENSDART00000102148
ddx3b
DEAD (Asp-Glu-Ala-Asp) box helicase 3b
chr7_+_13609457 0.92 ENSDART00000172857
ankdd1a
ankyrin repeat and death domain containing 1A
chr20_-_33704753 0.92 ENSDART00000157427
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr14_+_12178915 0.92 ENSDART00000054626
hdac3
histone deacetylase 3
chr5_-_22602979 0.91 ENSDART00000146287
nono
non-POU domain containing, octamer-binding
chr19_+_7636941 0.90 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr20_+_4221978 0.90 ENSDART00000171898
ipcef1
interaction protein for cytohesin exchange factors 1
chr12_+_23991639 0.90 ENSDART00000003143
psme4b
proteasome activator subunit 4b
chr13_-_42721076 0.90 ENSDART00000160472
capn1a
calpain 1, (mu/I) large subunit a
chr20_-_29499363 0.90 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
rrm2
ribonucleotide reductase M2 polypeptide
chr13_+_33268657 0.90 ENSDART00000002095
tmem39b
transmembrane protein 39B
chr20_-_6196989 0.90 ENSDART00000013343
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr18_-_25051846 0.90 ENSDART00000013082
st8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr6_+_32382743 0.89 ENSDART00000190009
dock7
dedicator of cytokinesis 7
chr9_+_54716436 0.89 ENSDART00000000552
ofd1
oral-facial-digital syndrome 1
chr2_+_26240339 0.89 ENSDART00000191006
palm1b
paralemmin 1b
chr14_-_8080416 0.89 ENSDART00000045109
zgc:92242
zgc:92242
chr9_-_41401564 0.88 ENSDART00000059628
nab1b
NGFI-A binding protein 1b (EGR1 binding protein 1)
chr13_+_29926326 0.88 ENSDART00000131609
cuedc2
CUE domain containing 2
chr3_-_58823762 0.88 ENSDART00000101253
luc7l3
LUC7-like 3 pre-mRNA splicing factor
chr2_-_38204845 0.88 ENSDART00000142342
acin1a
apoptotic chromatin condensation inducer 1a
chr7_+_24006875 0.87 ENSDART00000033755
homezb
homeobox and leucine zipper encoding b
chr23_+_36730713 0.87 ENSDART00000113179
tspan31
tetraspanin 31
chr8_+_17869225 0.87 ENSDART00000080079
slc44a5b
solute carrier family 44, member 5b
chr12_+_23991276 0.86 ENSDART00000153136
psme4b
proteasome activator subunit 4b
chr25_-_21492630 0.86 ENSDART00000141481
immp2l
inner mitochondrial membrane peptidase subunit 2
chr25_+_22017182 0.86 ENSDART00000156517
si:dkey-217l24.1
si:dkey-217l24.1
chr23_-_31645760 0.86 ENSDART00000035031
sgk1
serum/glucocorticoid regulated kinase 1
chr5_+_4016271 0.85 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
ggnbp2
gametogenetin binding protein 2
chr5_-_22602780 0.85 ENSDART00000011699
nono
non-POU domain containing, octamer-binding
chr10_-_33156789 0.85 ENSDART00000192268
ENSDART00000182065
ENSDART00000081170
cux1a
cut-like homeobox 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of lef1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0061037 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.6 3.2 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.5 2.1 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.5 5.4 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 2.1 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.4 1.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 1.3 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 2.1 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.4 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.4 1.1 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.4 1.4 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.3 1.7 GO:0036088 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.3 4.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.3 1.0 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.3 0.9 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.3 0.9 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.3 1.8 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.3 1.8 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.3 6.1 GO:0008078 mesodermal cell migration(GO:0008078)
0.3 0.8 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.3 2.3 GO:0006465 signal peptide processing(GO:0006465)
0.2 0.7 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.2 1.7 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.2 1.0 GO:0032801 receptor catabolic process(GO:0032801)
0.2 1.0 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 1.6 GO:0070285 pigment cell development(GO:0070285)
0.2 0.7 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.2 0.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.2 1.3 GO:0044209 AMP salvage(GO:0044209)
0.2 0.8 GO:0010039 response to iron ion(GO:0010039)
0.2 1.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 1.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 0.7 GO:2000048 activation of phospholipase D activity(GO:0031584) negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 0.2 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.2 0.7 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 3.9 GO:0060541 respiratory system development(GO:0060541)
0.2 1.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 0.5 GO:2000434 regulation of protein neddylation(GO:2000434)
0.2 0.8 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.2 0.5 GO:0051026 chiasma assembly(GO:0051026)
0.2 0.8 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.2 3.5 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 1.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.2 1.5 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.2 1.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 1.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 1.8 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 2.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.0 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.4 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 1.7 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 1.0 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.1 1.3 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 0.8 GO:0030242 pexophagy(GO:0030242)
0.1 1.5 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 2.3 GO:0006265 DNA topological change(GO:0006265)
0.1 0.7 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.1 1.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.9 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.4 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.9 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.1 GO:0001709 cell fate determination(GO:0001709)
0.1 1.3 GO:0033198 response to ATP(GO:0033198)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.5 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 1.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.3 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.5 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.3 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.5 GO:1901797 negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1 0.5 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.1 0.5 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 1.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.6 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 1.6 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 1.7 GO:0002574 thrombocyte differentiation(GO:0002574)
0.1 0.8 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.2 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.2 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 2.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.9 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 0.8 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.6 GO:0021634 optic nerve formation(GO:0021634)
0.1 0.4 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.5 GO:0061511 centriole elongation(GO:0061511)
0.1 0.4 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 0.7 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.8 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.8 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.3 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.1 0.5 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 1.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.9 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.5 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.5 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.9 GO:0061055 myotome development(GO:0061055)
0.1 0.6 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.5 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.4 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:2000047 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047)
0.1 1.0 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 1.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 2.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 5.7 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.1 0.2 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.4 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:1902750 negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.1 0.7 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.3 GO:0042088 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) regulation of type 2 immune response(GO:0002828) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) negative regulation of T cell differentiation(GO:0045581) regulation of T-helper cell differentiation(GO:0045622) negative regulation of T-helper cell differentiation(GO:0045623) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) negative regulation of alpha-beta T cell differentiation(GO:0046639) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.7 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 1.0 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 0.2 GO:1902946 protein localization to early endosome(GO:1902946)
0.0 0.4 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 5.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 1.0 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0030237 female sex determination(GO:0030237)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 2.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 1.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0043486 histone exchange(GO:0043486)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.9 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.4 GO:0070613 negative regulation of protein processing(GO:0010955) regulation of protein processing(GO:0070613) regulation of protein maturation(GO:1903317) negative regulation of protein maturation(GO:1903318)
0.0 4.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.9 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 3.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.1 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.4 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 1.1 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 1.2 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 2.7 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.8 GO:0006284 base-excision repair(GO:0006284)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 2.1 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 1.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.5 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.9 GO:0050684 regulation of mRNA processing(GO:0050684)
0.0 1.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.3 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.0 1.0 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 1.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.3 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 1.2 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.2 GO:0046512 sphingosine metabolic process(GO:0006670) diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0002931 response to ischemia(GO:0002931)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.4 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.4 GO:0072662 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.4 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 1.3 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 2.2 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.8 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0009408 response to heat(GO:0009408)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 GO:0045095 keratin filament(GO:0045095)
0.4 1.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 1.3 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.7 GO:0010369 chromocenter(GO:0010369)
0.2 0.9 GO:0044609 DBIRD complex(GO:0044609)
0.2 2.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 1.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 1.0 GO:0008091 spectrin(GO:0008091)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.2 0.9 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 1.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 2.3 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.5 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 1.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.8 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.7 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 1.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 2.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.3 GO:0072380 TRC complex(GO:0072380)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.3 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 6.1 GO:0032432 actin filament bundle(GO:0032432)
0.1 1.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.5 GO:0005685 U1 snRNP(GO:0005685)
0.1 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:0031464 inclusion body(GO:0016234) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.7 GO:0031526 brush border membrane(GO:0031526)
0.1 1.6 GO:0030686 90S preribosome(GO:0030686)
0.1 1.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.5 GO:0016586 RSC complex(GO:0016586)
0.1 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.2 GO:0030057 desmosome(GO:0030057)
0.1 2.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 2.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.6 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 1.1 GO:0008278 cohesin complex(GO:0008278)
0.0 3.8 GO:0000922 spindle pole(GO:0000922)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 9.3 GO:0005912 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 3.2 GO:0016607 nuclear speck(GO:0016607)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.9 GO:0043296 apical junction complex(GO:0043296)
0.0 2.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.0 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.8 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.9 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.6 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 2.3 GO:0005938 cell cortex(GO:0005938)
0.0 1.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 1.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.8 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.4 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.6 2.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.5 2.1 GO:0031005 filamin binding(GO:0031005)
0.5 1.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.3 1.7 GO:0016841 ammonia-lyase activity(GO:0016841)
0.3 1.3 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.3 2.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.3 1.0 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.3 0.9 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.3 0.8 GO:0003994 aconitate hydratase activity(GO:0003994)
0.3 2.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 0.7 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 0.7 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.2 1.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 2.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 2.4 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.2 2.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 0.8 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.2 3.6 GO:0008301 DNA binding, bending(GO:0008301)
0.2 1.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 2.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 1.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.2 1.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.8 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 3.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.9 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.7 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 2.2 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.9 GO:0008263 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.1 1.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.6 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.7 GO:0030619 U1 snRNA binding(GO:0030619)
0.1 1.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.6 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 7.3 GO:0045296 cadherin binding(GO:0045296)
0.1 0.8 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 1.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.8 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.8 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 1.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.6 GO:0070628 proteasome binding(GO:0070628)
0.1 5.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.2 GO:2001070 starch binding(GO:2001070)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.4 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 2.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.4 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 1.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 2.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 1.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 4.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 2.2 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.3 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.1 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) 5'-3' exonuclease activity(GO:0008409)
0.0 5.3 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 6.2 GO:0003682 chromatin binding(GO:0003682)
0.0 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.5 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 1.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.0 5.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.3 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 2.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 2.8 GO:0000989 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.8 GO:0046332 SMAD binding(GO:0046332)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.8 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 1.8 GO:0060090 binding, bridging(GO:0060090)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 6.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.2 2.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 1.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 4.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 1.6 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 4.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 7.2 PID E2F PATHWAY E2F transcription factor network
0.1 0.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 1.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 ST P38 MAPK PATHWAY p38 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 6.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 1.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.2 2.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 1.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.3 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 1.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 1.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 3.6 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.4 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 1.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination