Project

PRJNA438478: RNAseq of wild type zebrafish germline

Navigation
Downloads

Results for lhx1a+lhx1b

Z-value: 0.57

Motif logo

logo of

Transcription factors associated with lhx1a+lhx1b

Gene Symbol Gene ID Gene Info
lhx1b
ENSDARG00000007944 LIM homeobox 1b
lhx1a
ENSDARG00000014018 LIM homeobox 1a
lhx1b
ENSDARG00000111635 LIM homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx1adr11_v1_chr15_-_27710513_277105750.701.1e-03Click!
lhx1bdr11_v1_chr5_+_56268436_562684360.681.7e-03Click!

Activity profile of lhx1a+lhx1b motif

Sorted Z-values of lhx1a+lhx1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_38040407 1.72 ENSDART00000139936
si:dkey-111e8.4
si:dkey-111e8.4
chr3_+_39853788 1.66 ENSDART00000154869
cacna1ha
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr18_+_46382484 1.61 ENSDART00000024202
ENSDART00000142790
daw1
dynein assembly factor with WDR repeat domains 1
chr8_+_43340995 1.40 ENSDART00000038566
rflna
refilin A
chr11_-_2838699 1.35 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr24_-_26328721 1.26 ENSDART00000125468
apodb
apolipoprotein Db
chr15_-_20939579 1.22 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr12_+_45200744 1.08 ENSDART00000098932
wbp2
WW domain binding protein 2
chr12_+_7497882 1.05 ENSDART00000134608
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr6_-_21582444 1.01 ENSDART00000151339
si:dkey-43k4.3
si:dkey-43k4.3
chr17_+_15433518 0.95 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr16_-_28856112 0.93 ENSDART00000078543
syt11b
synaptotagmin XIb
chr17_+_15433671 0.85 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr7_+_20471315 0.81 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr22_-_24285432 0.79 ENSDART00000164083
si:ch211-117l17.4
si:ch211-117l17.4
chr11_-_25733910 0.79 ENSDART00000171935
brpf3a
bromodomain and PHD finger containing, 3a
chr19_+_43297546 0.78 ENSDART00000168002
laptm5
lysosomal protein transmembrane 5
chr3_+_45687266 0.76 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr13_-_9450210 0.73 ENSDART00000133768
pimr152
Pim proto-oncogene, serine/threonine kinase, related 152
chr20_-_45812144 0.73 ENSDART00000147897
ENSDART00000147637
fermt1
fermitin family member 1
chr7_-_52388734 0.70 ENSDART00000174186
wdr93
WD repeat domain 93
chr1_-_669717 0.69 ENSDART00000160564
cyyr1
cysteine/tyrosine-rich 1
chr5_+_2815021 0.68 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr3_-_31619463 0.65 ENSDART00000124559
moto
minamoto
chr25_+_22296666 0.63 ENSDART00000138887
ENSDART00000193410
cyp11a2
cytochrome P450, family 11, subfamily A, polypeptide 2
chr4_+_9669717 0.61 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr3_+_36424055 0.61 ENSDART00000170318
si:ch1073-443f11.2
si:ch1073-443f11.2
chr12_-_35830625 0.59 ENSDART00000180028
CU459056.1

chr18_-_17485419 0.58 ENSDART00000018764
foxl1
forkhead box L1
chr20_+_25586099 0.57 ENSDART00000063122
ENSDART00000134047
cyp2p10
cytochrome P450, family 2, subfamily P, polypeptide 10
chr4_-_9891874 0.56 ENSDART00000067193
adm2a
adrenomedullin 2a
chr24_-_38657683 0.53 ENSDART00000154843
si:ch1073-164k15.3
si:ch1073-164k15.3
chr23_-_16485190 0.53 ENSDART00000155038
si:dkeyp-100a5.4
si:dkeyp-100a5.4
chr4_+_72723304 0.50 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
rab3ip
RAB3A interacting protein (rabin3)
chr6_+_17053650 0.50 ENSDART00000155296
pimr16
Pim proto-oncogene, serine/threonine kinase, related 16
chr16_-_12173554 0.48 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr4_+_16885854 0.45 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr4_+_57881965 0.45 ENSDART00000162234
si:dkeyp-44b5.4
si:dkeyp-44b5.4
chr9_-_47472998 0.44 ENSDART00000134480
tns1b
tensin 1b
chr14_+_44794936 0.44 ENSDART00000128881
zgc:195212
zgc:195212
chr20_-_9095105 0.43 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr15_+_9861973 0.43 ENSDART00000170945
si:dkey-13m3.2
si:dkey-13m3.2
chr21_-_25801956 0.42 ENSDART00000101219
mettl27
methyltransferase like 27
chr20_+_11731039 0.40 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
si:ch211-155o21.3
chr2_-_30668580 0.40 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr21_-_13972745 0.40 ENSDART00000143874
akna
AT-hook transcription factor
chr1_+_10318089 0.39 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr13_+_646700 0.39 ENSDART00000006892
tp53bp2a
tumor protein p53 binding protein, 2a
chr16_-_12173399 0.39 ENSDART00000142574
clstn3
calsyntenin 3
chr9_+_28598577 0.38 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
si:ch73-7i4.1
chr24_-_31425799 0.36 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr22_-_12160283 0.35 ENSDART00000146785
ENSDART00000128176
tmem163b
transmembrane protein 163b
chr21_+_25802190 0.34 ENSDART00000128987
nf2b
neurofibromin 2b (merlin)
chr20_+_35438300 0.33 ENSDART00000102504
ENSDART00000153249
tdrd6
tudor domain containing 6
chr6_+_11989537 0.32 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr6_+_7444899 0.32 ENSDART00000053775
arf3b
ADP-ribosylation factor 3b
chr9_-_14504834 0.32 ENSDART00000056103
nrp2b
neuropilin 2b
chr22_-_5252005 0.31 ENSDART00000132942
ENSDART00000081801
ncln
nicalin
chr22_+_19552987 0.30 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr20_+_6035427 0.29 ENSDART00000054086
tshr
thyroid stimulating hormone receptor
chr8_-_45760087 0.29 ENSDART00000025620
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr12_-_6880694 0.28 ENSDART00000171846
pcdh15b
protocadherin-related 15b
chr7_-_38658411 0.28 ENSDART00000109463
ENSDART00000017155
npsn
nephrosin
chr9_+_34641237 0.27 ENSDART00000133996
shox
short stature homeobox
chr2_+_38373272 0.26 ENSDART00000113111
psmb5
proteasome subunit beta 5
chr2_+_42072231 0.26 ENSDART00000084517
vcpip1
valosin containing protein (p97)/p47 complex interacting protein 1
chr4_+_77943184 0.24 ENSDART00000159094
pacsin2
protein kinase C and casein kinase substrate in neurons 2
chr3_-_15999501 0.24 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr24_-_40860603 0.23 ENSDART00000188032
CU633479.7

chr15_-_22074315 0.23 ENSDART00000149830
drd2a
dopamine receptor D2a
chr10_-_11261565 0.23 ENSDART00000146727
ptbp3
polypyrimidine tract binding protein 3
chr22_-_19552796 0.23 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
si:dkey-78l4.14
chr24_+_13316737 0.22 ENSDART00000191658
SBSPON
somatomedin B and thrombospondin type 1 domain containing
chr17_+_45405821 0.22 ENSDART00000189482
ENSDART00000177422
tagapa
T cell activation RhoGTPase activating protein a
chr2_+_2223837 0.21 ENSDART00000101038
ENSDART00000129354
tmie
transmembrane inner ear
chr23_-_4409668 0.21 ENSDART00000081823
si:ch73-142c19.1
si:ch73-142c19.1
chr21_-_20939488 0.19 ENSDART00000039043
rgs7bpb
regulator of G protein signaling 7 binding protein b
chr1_+_51039558 0.19 ENSDART00000024743
dpy30
dpy-30 histone methyltransferase complex regulatory subunit
chr16_+_2820340 0.18 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
si:dkey-288i20.2
chr3_-_29941357 0.18 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
grna
granulin a
chr10_-_11261386 0.17 ENSDART00000189946
ptbp3
polypyrimidine tract binding protein 3
chr3_-_48716422 0.17 ENSDART00000164979
si:ch211-114m9.1
si:ch211-114m9.1
chr1_-_45616470 0.17 ENSDART00000150165
atf7ip
activating transcription factor 7 interacting protein
chr6_-_43677125 0.16 ENSDART00000150128
foxp1b
forkhead box P1b
chr1_+_21731382 0.16 ENSDART00000054395
pax5
paired box 5
chr20_-_40755614 0.16 ENSDART00000061247
cx32.3
connexin 32.3
chr2_-_16217344 0.15 ENSDART00000152031
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr14_-_413273 0.15 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr1_+_6172786 0.14 ENSDART00000126468
prkag3a
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr10_+_16584382 0.13 ENSDART00000112039
CR790388.1

chr11_-_41853874 0.13 ENSDART00000002556
mrto4
MRT4 homolog, ribosome maturation factor
chr22_+_19553390 0.13 ENSDART00000061739
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr3_-_32818607 0.13 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr7_+_22809905 0.13 ENSDART00000166900
ENSDART00000143455
ENSDART00000126037
sf1
splicing factor 1
chr10_+_42423318 0.12 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr4_-_2219705 0.12 ENSDART00000131046
si:ch73-278m9.1
si:ch73-278m9.1
chr23_-_1660708 0.11 ENSDART00000175138
CU693481.1

chr22_-_8725768 0.11 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr9_-_9415000 0.10 ENSDART00000146210
si:ch211-214p13.9
si:ch211-214p13.9
chr6_-_30839763 0.10 ENSDART00000154228
sgip1a
SH3-domain GRB2-like (endophilin) interacting protein 1a
chr2_+_20406399 0.10 ENSDART00000006817
ENSDART00000137848
palmda
palmdelphin a
chr5_-_38094130 0.10 ENSDART00000131831
si:ch211-284e13.4
si:ch211-284e13.4
chr3_-_19368435 0.09 ENSDART00000132987
s1pr5a
sphingosine-1-phosphate receptor 5a
chr21_-_35419486 0.09 ENSDART00000138529
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr3_-_56541723 0.09 ENSDART00000156398
ENSDART00000050576
ENSDART00000184874
si:ch211-189a21.1
cyth1a
si:ch211-189a21.1
cytohesin 1a
chr22_-_36530902 0.09 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr9_+_37152564 0.08 ENSDART00000189497
gli2a
GLI family zinc finger 2a
chr4_+_52212057 0.08 ENSDART00000165627
znf1034
zinc finger protein 1034
chr8_-_53044300 0.08 ENSDART00000191653
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr15_-_14552101 0.08 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr18_+_8320165 0.07 ENSDART00000092053
chkb
choline kinase beta
chr6_+_39905021 0.07 ENSDART00000064904
endou
endonuclease, polyU-specific
chr7_+_27317174 0.07 ENSDART00000193058
sox6
SRY (sex determining region Y)-box 6
chr22_-_28226948 0.07 ENSDART00000147686
si:dkey-222p3.1
si:dkey-222p3.1
chr21_-_39327223 0.07 ENSDART00000115097
aifm5
apoptosis-inducing factor, mitochondrion-associated, 5
chr4_-_1801519 0.05 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr12_+_13118540 0.05 ENSDART00000077840
ENSDART00000127870
cmn
calymmin
chr24_-_35767501 0.05 ENSDART00000105680
ENSDART00000042290
ENSDART00000166264
dtna
dystrobrevin, alpha
chr24_+_28953089 0.05 ENSDART00000153761
rnpc3
RNA-binding region (RNP1, RRM) containing 3
chr13_-_12602920 0.04 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr23_-_31969786 0.04 ENSDART00000134550
ormdl2
ORMDL sphingolipid biosynthesis regulator 2
chr12_-_48006835 0.04 ENSDART00000108989
adamts14
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr17_-_10122204 0.04 ENSDART00000160751
BX088587.1

chr25_-_13490744 0.04 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr12_+_16168342 0.04 ENSDART00000079326
ENSDART00000170024
lrp2b
low density lipoprotein receptor-related protein 2b
chr16_+_23303859 0.03 ENSDART00000006093
slc50a1
solute carrier family 50 (sugar efflux transporter), member 1
chr12_-_17712393 0.03 ENSDART00000143534
ENSDART00000010144
pvalb2
parvalbumin 2
chr23_+_4689626 0.03 ENSDART00000131532
gp9
glycoprotein IX (platelet)
chr16_-_16761164 0.02 ENSDART00000135872
si:dkey-27n14.1
si:dkey-27n14.1
chr8_-_53926228 0.01 ENSDART00000015554
ubiad1
UbiA prenyltransferase domain containing 1
chr25_+_4751879 0.01 ENSDART00000169465
si:zfos-2372e4.1
si:zfos-2372e4.1
chr1_-_21287724 0.01 ENSDART00000193900
npy1r
neuropeptide Y receptor Y1
chr21_+_42717424 0.01 ENSDART00000166936
ENSDART00000172135
sh3pxd2b
SH3 and PX domains 2B
chr19_+_2631565 0.01 ENSDART00000171487
fam126a
family with sequence similarity 126, member A
chr6_-_35052388 0.01 ENSDART00000181000
ENSDART00000170116
uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
chr3_+_3681116 0.01 ENSDART00000109618
art4
ADP-ribosyltransferase 4 (Dombrock blood group)
chr5_-_30620625 0.00 ENSDART00000098273
tcnl
transcobalamin like
chr8_-_12867434 0.00 ENSDART00000081657
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx1a+lhx1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.7 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.7 GO:0007141 male meiosis I(GO:0007141)
0.1 1.6 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.3 GO:0048313 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.8 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 1.6 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 1.3 GO:0007568 aging(GO:0007568)
0.0 0.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 1.1 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.3 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 1.2 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:0042181 ketone biosynthetic process(GO:0042181)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.3 GO:0045762 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.1 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.2 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.6 GO:0042737 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.0 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.3 GO:0033391 chromatoid body(GO:0033391)
0.1 1.7 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 1.4 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0031005 filamin binding(GO:0031005)
0.2 1.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.7 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 1.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.4 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 1.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 1.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors