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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for lhx6

Z-value: 0.64

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Transcription factors associated with lhx6

Gene Symbol Gene ID Gene Info
lhx6
ENSDARG00000006896 LIM homeobox 6
lhx6
ENSDARG00000112520 LIM homeobox 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx6dr11_v1_chr10_+_9372702_9372702-0.933.1e-08Click!

Activity profile of lhx6 motif

Sorted Z-values of lhx6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_21362071 3.35 ENSDART00000125167
avd
avidin
chr8_-_23780334 3.26 ENSDART00000145179
ENSDART00000145894
zgc:195245
zgc:195245
chr10_-_21362320 3.13 ENSDART00000189789
avd
avidin
chr10_-_34002185 2.47 ENSDART00000046599
zar1l
zygote arrest 1-like
chr21_+_25777425 2.28 ENSDART00000021620
cldnd
claudin d
chr11_-_44801968 2.25 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr12_-_14143344 2.19 ENSDART00000152742
buc2l
bucky ball 2-like
chr12_-_33357655 2.14 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr9_-_35633827 1.96 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr2_-_15324837 1.91 ENSDART00000015655
tecrl2b
trans-2,3-enoyl-CoA reductase-like 2b
chr23_+_2728095 1.74 ENSDART00000066086
zgc:114123
zgc:114123
chr6_+_28208973 1.72 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
LSM2 (1 of many)
si:ch73-14h10.2
chr19_+_31585917 1.68 ENSDART00000132182
gmnn
geminin, DNA replication inhibitor
chr24_-_9979342 1.62 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr5_+_37903790 1.60 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr2_+_6253246 1.58 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr25_+_5972690 1.53 ENSDART00000067517
si:ch211-11i22.4
si:ch211-11i22.4
chr20_-_6532462 1.49 ENSDART00000054653
mcm3l
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr15_+_46313082 1.38 ENSDART00000153830
si:ch1073-190k2.1
si:ch1073-190k2.1
chr20_-_14114078 1.37 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr20_+_14114258 1.35 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr1_-_18811517 1.34 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr6_+_21001264 1.33 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr12_-_48188928 1.30 ENSDART00000184384
pald1a
phosphatase domain containing, paladin 1a
chr20_-_23426339 1.26 ENSDART00000004625
zar1
zygote arrest 1
chr21_-_32060993 1.17 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr1_-_55248496 1.06 ENSDART00000098615
nanos3
nanos homolog 3
chr17_-_40956035 1.04 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr10_-_34916208 1.00 ENSDART00000187371
ccna1
cyclin A1
chr13_+_38814521 0.96 ENSDART00000110976
col19a1
collagen, type XIX, alpha 1
chr14_+_8940326 0.95 ENSDART00000159920
rps6kal
ribosomal protein S6 kinase a, like
chr11_+_37638873 0.93 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
sh2d5
SH2 domain containing 5
chr14_+_15155684 0.92 ENSDART00000167966
zgc:158852
zgc:158852
chr7_-_59159253 0.92 ENSDART00000159285
haus6
HAUS augmin-like complex, subunit 6
chr2_-_26596794 0.89 ENSDART00000134685
ENSDART00000056787
zgc:113691
zgc:113691
chr10_+_11261576 0.88 ENSDART00000155333
hsdl2
hydroxysteroid dehydrogenase like 2
chr23_-_28120058 0.88 ENSDART00000087815
b4galnt1a
beta-1,4-N-acetyl-galactosaminyl transferase 1a
chr17_+_16046314 0.88 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr7_+_51795667 0.87 ENSDART00000174201
ENSDART00000073839
slc38a7
solute carrier family 38, member 7
chr14_+_34492288 0.86 ENSDART00000144301
wnt8a
wingless-type MMTV integration site family, member 8a
chr8_-_25034411 0.78 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr19_+_10661520 0.77 ENSDART00000091813
ENSDART00000165653
ago3b
argonaute RISC catalytic component 3b
chr20_+_29209767 0.76 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr16_+_47207691 0.76 ENSDART00000062507
ica1
islet cell autoantigen 1
chr5_+_25733774 0.74 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr23_-_10786400 0.74 ENSDART00000055038
rybpa
RING1 and YY1 binding protein a
chr25_-_6049339 0.74 ENSDART00000075184
snx1a
sorting nexin 1a
chr10_+_33393829 0.73 ENSDART00000163458
ENSDART00000115379
zgc:153345
zgc:153345
chr4_+_4849789 0.72 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr8_-_25033681 0.72 ENSDART00000003493
nfyal
nuclear transcription factor Y, alpha, like
chr6_+_50393047 0.72 ENSDART00000055502
ENSDART00000055511
ergic3
ERGIC and golgi 3
chr1_-_513762 0.71 ENSDART00000148162
ENSDART00000144606
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr15_+_28410664 0.71 ENSDART00000132028
ENSDART00000057697
ENSDART00000057257
pitpnaa
phosphatidylinositol transfer protein, alpha a
chr20_+_29209926 0.70 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr9_-_11676491 0.70 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr5_-_19006290 0.70 ENSDART00000137022
golga3
golgin A3
chr7_-_26532089 0.69 ENSDART00000121698
senp3b
SUMO1/sentrin/SMT3 specific peptidase 3b
chr14_+_35428152 0.69 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr11_+_18873619 0.68 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr1_-_23308225 0.67 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr10_-_35257458 0.66 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
prr11
proline rich 11
chr8_-_15129573 0.66 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr22_-_21897203 0.66 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr23_-_33709964 0.66 ENSDART00000143333
ENSDART00000130338
pou6f1
POU class 6 homeobox 1
chr5_+_29851433 0.65 ENSDART00000143434
ubash3ba
ubiquitin associated and SH3 domain containing Ba
chr13_-_35808904 0.64 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr15_+_17345609 0.62 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr9_-_746317 0.62 ENSDART00000129632
ENSDART00000130720
usp37
ubiquitin specific peptidase 37
chr24_+_29912509 0.62 ENSDART00000168422
frrs1b
ferric-chelate reductase 1b
chr23_-_36446307 0.62 ENSDART00000136623
zgc:174906
zgc:174906
chr20_+_29209615 0.61 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr5_+_60590796 0.61 ENSDART00000159859
tmem132e
transmembrane protein 132E
chr1_+_13930625 0.61 ENSDART00000111026
noctb
nocturnin b
chr6_-_12172424 0.60 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr17_+_37227936 0.59 ENSDART00000076009
hadhab
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr7_-_49594995 0.58 ENSDART00000174161
ENSDART00000109147
brsk2b
BR serine/threonine kinase 2b
chr12_-_35393211 0.57 ENSDART00000137139
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr1_+_35985813 0.56 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr24_+_19415124 0.55 ENSDART00000186931
sulf1
sulfatase 1
chr15_-_18115540 0.54 ENSDART00000131639
ENSDART00000047902
arcn1b
archain 1b
chr12_+_22580579 0.53 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr8_-_49728590 0.52 ENSDART00000135714
ENSDART00000138810
ENSDART00000098319
gkap1
G kinase anchoring protein 1
chr4_-_2637689 0.52 ENSDART00000192550
ENSDART00000021953
ENSDART00000150344
cog5
component of oligomeric golgi complex 5
chr5_-_25733745 0.52 ENSDART00000051566
zgc:101016
zgc:101016
chr13_+_38817871 0.52 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr5_+_36768674 0.51 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr25_-_10791437 0.51 ENSDART00000127054
BX572619.1

chr4_+_2637947 0.50 ENSDART00000130623
dus4l
dihydrouridine synthase 4-like (S. cerevisiae)
chr2_+_26237322 0.50 ENSDART00000030520
palm1b
paralemmin 1b
chr1_-_40102836 0.50 ENSDART00000147317
cntf
ciliary neurotrophic factor
chr1_+_513986 0.49 ENSDART00000109083
ENSDART00000081945
txnl4b
thioredoxin-like 4B
chr14_-_16082806 0.49 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr21_-_18275226 0.48 ENSDART00000126672
ENSDART00000135239
brd3a
bromodomain containing 3a
chr22_-_14247276 0.48 ENSDART00000033332
si:ch211-246m6.5
si:ch211-246m6.5
chr23_-_2901167 0.47 ENSDART00000165955
ENSDART00000190616
zhx3
zinc fingers and homeoboxes 3
chr12_-_18577983 0.47 ENSDART00000193262
zdhhc4
zinc finger, DHHC-type containing 4
chr25_+_35891342 0.46 ENSDART00000147093
lsm14aa
LSM14A mRNA processing body assembly factor a
chr24_-_25004553 0.46 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr20_-_9436521 0.45 ENSDART00000133000
zgc:101840
zgc:101840
chr21_-_39177564 0.45 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr23_-_29394505 0.44 ENSDART00000017728
pgd
phosphogluconate dehydrogenase
chr3_-_26787430 0.43 ENSDART00000087047
rab40c
RAB40c, member RAS oncogene family
chr20_-_37813863 0.43 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr17_+_49281597 0.42 ENSDART00000155599
zgc:113176
zgc:113176
chr8_-_23776399 0.42 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr2_+_40294313 0.41 ENSDART00000037292
epha4b
eph receptor A4b
chr5_-_67241633 0.41 ENSDART00000114783
clip1a
CAP-GLY domain containing linker protein 1a
chr19_-_12648122 0.40 ENSDART00000151184
fam210aa
family with sequence similarity 210, member Aa
chr16_-_41714988 0.40 ENSDART00000138798
cep85
centrosomal protein 85
chr15_-_9272328 0.40 ENSDART00000172114
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr9_+_18829360 0.39 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr15_+_21262917 0.39 ENSDART00000101000
gkup
glucuronokinase with putative uridyl pyrophosphorylase
chr4_-_77557279 0.39 ENSDART00000180113
AL935186.10

chr23_+_27782071 0.38 ENSDART00000131379
kmt2d
lysine (K)-specific methyltransferase 2D
chr6_-_55585423 0.38 ENSDART00000157129
slc12a5a
solute carrier family 12 (potassium/chloride transporter), member 5a
chr17_+_8799661 0.38 ENSDART00000105326
tonsl
tonsoku-like, DNA repair protein
chr4_+_25917915 0.37 ENSDART00000138603
vezt
vezatin, adherens junctions transmembrane protein
chr8_-_21142550 0.37 ENSDART00000143192
ENSDART00000186820
ENSDART00000135938
cpt2
carnitine palmitoyltransferase 2
chr10_-_32494499 0.35 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr4_-_73756673 0.35 ENSDART00000174274
ENSDART00000192913
ENSDART00000113546
BX855614.4
si:dkey-262g12.14
zgc:171551

si:dkey-262g12.14
zgc:171551
chr9_-_50001606 0.35 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr2_-_38363017 0.34 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr17_-_43594864 0.34 ENSDART00000139980
zfyve28
zinc finger, FYVE domain containing 28
chr20_-_48604199 0.34 ENSDART00000161762
ENSDART00000170894
mgst3a
microsomal glutathione S-transferase 3a
chr25_-_29087925 0.34 ENSDART00000171758
rpp25a
ribonuclease P and MRP subunit p25, a
chr9_-_3934963 0.33 ENSDART00000062336
ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr20_+_28803977 0.33 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr3_+_27798094 0.32 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr6_-_40922971 0.32 ENSDART00000155363
sfi1
SFI1 centrin binding protein
chr3_+_53116172 0.32 ENSDART00000115117
brd4
bromodomain containing 4
chr6_-_3982783 0.32 ENSDART00000171944
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr13_-_31017960 0.31 ENSDART00000145287
wdfy4
WDFY family member 4
chr17_+_8799451 0.31 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr21_+_20386865 0.31 ENSDART00000144366
si:dkey-30k6.5
si:dkey-30k6.5
chr6_-_40713183 0.31 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr10_-_42519773 0.31 ENSDART00000039187
march5l
membrane-associated ring finger (C3HC4) 5, like
chr7_+_36898850 0.31 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr7_+_17908235 0.31 ENSDART00000077113
mta2
metastasis associated 1 family, member 2
chr13_+_2442841 0.30 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
arfgef3
ARFGEF family member 3
chr13_+_40501455 0.30 ENSDART00000114985
hpse2
heparanase 2
chr4_-_4834617 0.30 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr24_+_16547035 0.30 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr19_-_12648408 0.30 ENSDART00000103692
fam210aa
family with sequence similarity 210, member Aa
chr9_-_28274932 0.29 ENSDART00000137582
ENSDART00000146932
creb1b
cAMP responsive element binding protein 1b
chr5_+_19933356 0.29 ENSDART00000088819
ankrd13a
ankyrin repeat domain 13A
chr18_-_15551360 0.29 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr14_+_29941445 0.29 ENSDART00000181761
fam149a
family with sequence similarity 149 member A
chr3_+_45364849 0.29 ENSDART00000153974
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr10_-_32494304 0.29 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr5_-_68093169 0.27 ENSDART00000051849
slc25a11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr3_-_43356082 0.27 ENSDART00000171213
uncx
UNC homeobox
chr21_+_18274825 0.27 ENSDART00000144322
ENSDART00000147768
wdr5
WD repeat domain 5
chr18_+_17725410 0.26 ENSDART00000090608
rspry1
ring finger and SPRY domain containing 1
chr20_-_34750363 0.26 ENSDART00000152845
znf395b
zinc finger protein 395b
chr6_-_48418021 0.26 ENSDART00000090528
rhoca
ras homolog family member Ca
chr1_-_21563040 0.25 ENSDART00000049572
ncapd3
non-SMC condensin II complex, subunit D3
chr13_+_15838151 0.25 ENSDART00000008987
klc1a
kinesin light chain 1a
chr24_+_39518774 0.25 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr3_-_61162750 0.25 ENSDART00000055064
pvalb8
parvalbumin 8
chr9_+_50001746 0.25 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr7_-_30174882 0.24 ENSDART00000110409
frmd5
FERM domain containing 5
chr19_+_47502581 0.24 ENSDART00000171526
CU695215.2

chr8_+_25034544 0.24 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr1_-_15797663 0.24 ENSDART00000177122
SGCZ
sarcoglycan zeta
chr12_+_48803098 0.23 ENSDART00000074768
ppifb
peptidylprolyl isomerase Fb
chr4_-_4834347 0.23 ENSDART00000141803
coa6
cytochrome c oxidase assembly factor 6
chr21_+_42226113 0.23 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr11_+_31864921 0.22 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr16_+_33144306 0.22 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr21_+_34814444 0.22 ENSDART00000161816
wdr55
WD repeat domain 55
chr9_-_43538328 0.22 ENSDART00000140526
znf385b
zinc finger protein 385B
chr9_+_17983463 0.22 ENSDART00000182150
akap11
A kinase (PRKA) anchor protein 11
chr2_+_37140448 0.22 ENSDART00000045016
ENSDART00000142940
pex19
peroxisomal biogenesis factor 19
chr5_+_61301525 0.21 ENSDART00000128773
doc2b
double C2-like domains, beta
chr23_-_46020226 0.21 ENSDART00000160010
SYDE2
synapse defective Rho GTPase homolog 2
chr11_+_5588122 0.21 ENSDART00000113281
zgc:172302
zgc:172302
chr17_-_22552678 0.20 ENSDART00000079401
si:ch211-125o16.4
si:ch211-125o16.4
chr4_+_3980247 0.20 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr5_-_69004007 0.20 ENSDART00000137443
ank1a
ankyrin 1, erythrocytic a
chr10_+_13000669 0.20 ENSDART00000158919
ENSDART00000172625
lpar1
lysophosphatidic acid receptor 1
chr24_-_39518599 0.19 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr5_-_15851953 0.19 ENSDART00000173101
si:dkey-1k23.3
si:dkey-1k23.3
chr21_+_26748141 0.19 ENSDART00000169025
pcxa
pyruvate carboxylase a
chr20_+_41021054 0.18 ENSDART00000146052
man1a1
mannosidase, alpha, class 1A, member 1
chr20_-_34750045 0.18 ENSDART00000186130
znf395b
zinc finger protein 395b
chr16_-_26855936 0.18 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr7_-_12464412 0.18 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr10_-_11385155 0.18 ENSDART00000064214
plac8.1
placenta-specific 8, tandem duplicate 1
chr8_-_49766205 0.17 ENSDART00000137941
ENSDART00000097919
ENSDART00000147309
hnrnpk
heterogeneous nuclear ribonucleoprotein K
chr18_+_2554666 0.17 ENSDART00000167218
p2ry2.1
purinergic receptor P2Y2, tandem duplicate 1
chr13_+_38521152 0.17 ENSDART00000145292
adgrb3
adhesion G protein-coupled receptor B3
chr22_-_20166660 0.17 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr7_-_7692723 0.17 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr17_-_37395460 0.17 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr23_-_18130264 0.16 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr19_-_42588510 0.16 ENSDART00000102583
sytl1
synaptotagmin-like 1
chr9_-_51436377 0.16 ENSDART00000006612
tbr1b
T-box, brain, 1b
chr9_+_19529951 0.16 ENSDART00000125416
pknox1.1
pbx/knotted 1 homeobox 1.1
chr17_+_20589553 0.15 ENSDART00000154447
si:ch73-288o11.4
si:ch73-288o11.4
chr13_-_38088627 0.15 ENSDART00000175268
CT027676.1

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.9 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.3 1.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 1.7 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 1.5 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.2 0.9 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.7 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 0.5 GO:0051645 Golgi localization(GO:0051645)
0.1 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 2.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.4 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.1 1.6 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.8 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 0.3 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.1 1.7 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.6 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.4 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 1.9 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 0.2 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 1.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.3 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.2 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.4 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:1904869 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.7 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.4 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 1.0 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:2000434 regulation of protein neddylation(GO:2000434)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.6 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0060465 pharynx development(GO:0060465)
0.0 0.3 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 2.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 1.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.5 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 1.0 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 1.5 GO:0048846 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.7 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.6 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 1.3 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.1 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.3 0.9 GO:0097189 apoptotic body(GO:0097189)
0.2 0.9 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 1.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 2.2 GO:0042555 MCM complex(GO:0042555)
0.1 0.8 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.3 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.7 GO:0030904 retromer complex(GO:0030904)
0.1 2.2 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.7 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 2.7 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.1 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.7 GO:0009374 biotin binding(GO:0009374)
0.3 0.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.2 0.6 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 2.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.7 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.1 1.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.1 0.5 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.8 GO:0035198 miRNA binding(GO:0035198)
0.1 0.7 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 1.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.3 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 2.0 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.3 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.0 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.7 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation