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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for lhx8a+lhx8b

Z-value: 0.66

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Transcription factors associated with lhx8a+lhx8b

Gene Symbol Gene ID Gene Info
lhx8a
ENSDARG00000002330 LIM homeobox 8a
lhx8b
ENSDARG00000042145 LIM homeobox 8b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx8adr11_v1_chr2_+_11205795_11205795-0.644.1e-03Click!
lhx8bdr11_v1_chr8_-_17926620_179266200.233.6e-01Click!

Activity profile of lhx8a+lhx8b motif

Sorted Z-values of lhx8a+lhx8b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_32384683 0.95 ENSDART00000182942
ENSDART00000141757
ubtfl
upstream binding transcription factor, like
chr11_+_13424116 0.86 ENSDART00000125563
homer3b
homer scaffolding protein 3b
chr11_+_13423776 0.66 ENSDART00000102553
homer3b
homer scaffolding protein 3b
chr8_+_29635968 0.61 ENSDART00000139029
ENSDART00000091409
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr11_-_43200994 0.59 ENSDART00000164700
sptbn1
spectrin, beta, non-erythrocytic 1
chr17_+_10570906 0.57 ENSDART00000182371
ENSDART00000176097
ENSDART00000110593
ENSDART00000169356
mgaa
MGA, MAX dimerization protein a
chr21_-_36571804 0.57 ENSDART00000138129
wwc1
WW and C2 domain containing 1
chr10_+_20364009 0.57 ENSDART00000186139
ENSDART00000080395
golga7
golgin A7
chr8_+_29636431 0.56 ENSDART00000133047
smarcad1a
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr4_+_14727018 0.56 ENSDART00000124189
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr18_-_158541 0.55 ENSDART00000188914
ENSDART00000191052
trpm7
transient receptor potential cation channel, subfamily M, member 7
chr2_+_49644803 0.52 ENSDART00000160342
si:ch211-209f23.7
si:ch211-209f23.7
chr4_+_14727212 0.51 ENSDART00000158094
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr7_+_13609457 0.50 ENSDART00000172857
ankdd1a
ankyrin repeat and death domain containing 1A
chr20_-_7080427 0.49 ENSDART00000140166
ENSDART00000023677
si:ch211-121a2.2
si:ch211-121a2.2
chr7_+_41887429 0.49 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr15_-_34866219 0.49 ENSDART00000099723
sh3bp5la
SH3-binding domain protein 5-like, a
chr16_-_36979592 0.48 ENSDART00000168443
snrnp48
small nuclear ribonucleoprotein 48 (U11/U12)
chr15_+_11427620 0.47 ENSDART00000168688
ndufc2
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr8_+_10823069 0.46 ENSDART00000081341
mapk13
mitogen-activated protein kinase 13
chr16_-_21903083 0.45 ENSDART00000165849
setdb1b
SET domain, bifurcated 1b
chr15_-_34865952 0.44 ENSDART00000186868
sh3bp5la
SH3-binding domain protein 5-like, a
chr21_-_13662237 0.44 ENSDART00000091647
ENSDART00000151547
pnpla7a
patatin-like phospholipase domain containing 7a
chr19_+_46222428 0.44 ENSDART00000183984
vps28
vacuolar protein sorting 28 (yeast)
chr1_+_45671687 0.44 ENSDART00000146101
mcoln1a
mucolipin 1a
chr20_+_6535438 0.44 ENSDART00000145763
si:ch211-191a24.4
si:ch211-191a24.4
chr7_-_39378903 0.42 ENSDART00000173659
slc8b1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr23_-_29668286 0.42 ENSDART00000129248
clstn1
calsyntenin 1
chr25_+_19238175 0.42 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
ppip5k1b
diphosphoinositol pentakisphosphate kinase 1b
chr24_+_39027481 0.41 ENSDART00000085565
capn15
calpain 15
chr9_-_12401871 0.40 ENSDART00000191901
nup35
nucleoporin 35
chr5_+_44944778 0.40 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
dmrt1
doublesex and mab-3 related transcription factor 1
chr5_-_15494164 0.40 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
taok3a
TAO kinase 3a
chr13_+_29925397 0.39 ENSDART00000123482
cuedc2
CUE domain containing 2
chr4_-_5775507 0.38 ENSDART00000021753
ccnc
cyclin C
chr16_-_35329803 0.38 ENSDART00000161729
ENSDART00000157700
ENSDART00000184584
ENSDART00000174713
ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr17_-_29271359 0.37 ENSDART00000104219
rcor1
REST corepressor 1
chr25_-_36263115 0.36 ENSDART00000143046
ENSDART00000139002
dus2
dihydrouridine synthase 2
chr21_-_34926619 0.36 ENSDART00000065337
ENSDART00000192740
kif20a
kinesin family member 20A
chr3_-_33935200 0.35 ENSDART00000151211
gtf2f1
general transcription factor IIF, polypeptide 1
chr14_-_23801389 0.35 ENSDART00000054264
nr3c1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_28518349 0.34 ENSDART00000159961
stag2b
stromal antigen 2b
chr17_+_15559046 0.34 ENSDART00000187126
bach2a
BTB and CNC homology 1, basic leucine zipper transcription factor 2a
chr5_+_36654817 0.34 ENSDART00000131339
capns1a
calpain, small subunit 1 a
chr7_-_32629458 0.34 ENSDART00000001376
arl14ep
ADP-ribosylation factor-like 14 effector protein
chr9_+_42606681 0.34 ENSDART00000191186
gulp1a
GULP, engulfment adaptor PTB domain containing 1a
chr3_-_30488063 0.34 ENSDART00000055393
ENSDART00000151367
med25
mediator complex subunit 25
chr4_+_9536860 0.33 ENSDART00000130083
lsm8
LSM8 homolog, U6 small nuclear RNA associated
chr25_+_21098675 0.33 ENSDART00000079012
rad52
RAD52 homolog, DNA repair protein
chr17_-_33412868 0.33 ENSDART00000187521
BX323819.1

chr8_-_16725959 0.32 ENSDART00000183593
depdc1a
DEP domain containing 1a
chr14_-_33945692 0.32 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr6_+_2195625 0.32 ENSDART00000155659
acvr1bb
activin A receptor type 1Bb
chr24_+_12945803 0.32 ENSDART00000005105
psme1
proteasome activator subunit 1
chr14_+_8638353 0.32 ENSDART00000163240
si:dkeyp-115e12.6
si:dkeyp-115e12.6
chr8_-_16725573 0.32 ENSDART00000049676
depdc1a
DEP domain containing 1a
chr24_+_792429 0.31 ENSDART00000082523
impa2
inositol(myo)-1(or 4)-monophosphatase 2
chr21_+_27302752 0.31 ENSDART00000012855
sart1
SART1, U4/U6.U5 tri-snRNP-associated protein 1
chr13_-_8892514 0.30 ENSDART00000144553
plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr1_-_55873178 0.30 ENSDART00000019936
prkacab
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b
chr3_-_33934788 0.29 ENSDART00000151411
gtf2f1
general transcription factor IIF, polypeptide 1
chr9_+_42607138 0.29 ENSDART00000138133
ENSDART00000002027
gulp1a
GULP, engulfment adaptor PTB domain containing 1a
chr5_+_13326765 0.29 ENSDART00000090851
ydjc
YdjC chitooligosaccharide deacetylase homolog
chr9_+_25775816 0.28 ENSDART00000127834
ENSDART00000189994
zeb2a
zinc finger E-box binding homeobox 2a
chr24_-_32025637 0.28 ENSDART00000180448
ENSDART00000159034
rsu1
Ras suppressor protein 1
chr13_+_29292011 0.28 ENSDART00000115023
parga
poly (ADP-ribose) glycohydrolase a
chr5_+_57320113 0.28 ENSDART00000036331
atp6v1g1
ATPase H+ transporting V1 subunit G1
chr4_+_15605844 0.27 ENSDART00000101619
ENSDART00000021384
exoc4
exocyst complex component 4
chr17_+_24590177 0.27 ENSDART00000092941
rlf
rearranged L-myc fusion
chr19_-_31042570 0.27 ENSDART00000144337
ENSDART00000136213
ENSDART00000133101
ENSDART00000190949
bzw2
basic leucine zipper and W2 domains 2
chr17_+_41081512 0.27 ENSDART00000056742
babam2
BRISC and BRCA1 A complex member 2
chr1_-_7673376 0.27 ENSDART00000013264
arglu1b
arginine and glutamate rich 1b
chr18_+_26899316 0.27 ENSDART00000050230
tspan3a
tetraspanin 3a
chr21_-_44771213 0.26 ENSDART00000188534
kif4
kinesin family member 4
chr22_-_910926 0.26 ENSDART00000180075
FP016205.1

chr22_-_15562933 0.25 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr24_+_33589667 0.25 ENSDART00000152097
dnah5l
dynein, axonemal, heavy chain 5 like
chr20_-_33507458 0.25 ENSDART00000140287
paplnb
papilin b, proteoglycan-like sulfated glycoprotein
chr10_+_17747880 0.25 ENSDART00000135044
pigo
phosphatidylinositol glycan anchor biosynthesis, class O
chr16_-_35427060 0.25 ENSDART00000172294
ctps1b
CTP synthase 1b
chr2_+_50062165 0.24 ENSDART00000097939
ENSDART00000138214
zcchc2
zinc finger, CCHC domain containing 2
chr1_+_10019653 0.24 ENSDART00000190227
trim2b
tripartite motif containing 2b
chr19_+_366034 0.24 ENSDART00000093383
vps72
vacuolar protein sorting 72 homolog (S. cerevisiae)
chr13_-_24260609 0.24 ENSDART00000138747
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr6_-_16456093 0.24 ENSDART00000083305
ENSDART00000181640
slc19a2
solute carrier family 19 (thiamine transporter), member 2
chr17_+_21486047 0.24 ENSDART00000104608
pla2g4f.2
phospholipase A2, group IVF, tandem duplicate 2
chr15_-_25613114 0.23 ENSDART00000182431
ENSDART00000187405
taok1a
TAO kinase 1a
chr13_+_8892784 0.23 ENSDART00000075054
ENSDART00000143705
thada
thyroid adenoma associated
chr24_+_39137001 0.23 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
tbc1d24
TBC1 domain family, member 24
chr2_-_22659450 0.23 ENSDART00000115025
thap4
THAP domain containing 4
chr15_-_45356635 0.23 ENSDART00000192000
CABZ01068246.1

chr11_+_36355348 0.23 ENSDART00000145427
sypl2a
synaptophysin-like 2a
chr7_-_51727760 0.23 ENSDART00000174180
hdac8
histone deacetylase 8
chr15_-_5901514 0.22 ENSDART00000155252
si:ch73-281n10.2
si:ch73-281n10.2
chr6_-_12456077 0.22 ENSDART00000190107
gpd2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr7_-_30280934 0.22 ENSDART00000126741
serf2
small EDRK-rich factor 2
chr25_+_15938880 0.21 ENSDART00000089035
ppfibp2b
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr9_-_16218097 0.21 ENSDART00000190503
myo1b
myosin IB
chr22_+_1313046 0.21 ENSDART00000170421
si:ch73-138e16.6
si:ch73-138e16.6
chr3_-_45281350 0.20 ENSDART00000020168
kctd5a
potassium channel tetramerization domain containing 5a
chr21_-_25601648 0.20 ENSDART00000042578
efemp2b
EGF containing fibulin extracellular matrix protein 2b
chr21_-_8153165 0.20 ENSDART00000182580
CABZ01074363.1

chr7_-_64770456 0.20 ENSDART00000192618
zdhhc21
zinc finger, DHHC-type containing 21
chr16_+_25535993 0.19 ENSDART00000077436
mylipb
myosin regulatory light chain interacting protein b
chr21_+_21201346 0.19 ENSDART00000142961
rictorb
RPTOR independent companion of MTOR, complex 2b
chr5_-_8614217 0.19 ENSDART00000164844
rictora
RPTOR independent companion of MTOR, complex 2 a
chr13_+_43650632 0.19 ENSDART00000141024
zfyve21
zinc finger, FYVE domain containing 21
chr6_+_40661703 0.18 ENSDART00000142492
eno1b
enolase 1b, (alpha)
chr7_+_72469724 0.18 ENSDART00000187629
HECTD4
HECT domain E3 ubiquitin protein ligase 4
chr11_+_44236183 0.18 ENSDART00000193470
gnb4b
guanine nucleotide binding protein (G protein), beta polypeptide 4b
chr1_+_7414318 0.18 ENSDART00000127426
si:ch73-383l1.1
si:ch73-383l1.1
chr8_+_7737062 0.18 ENSDART00000166712
fgd1
FYVE, RhoGEF and PH domain containing 1
chr12_-_24812403 0.17 ENSDART00000185517
foxn2b
forkhead box N2b
chr3_+_50201240 0.17 ENSDART00000156347
epn3a
epsin 3a
chr8_+_3820134 0.16 ENSDART00000122454
citb
citron rho-interacting serine/threonine kinase b
chr7_-_2285499 0.16 ENSDART00000182211
si:dkey-187j14.6
si:dkey-187j14.6
chr9_-_25055722 0.16 ENSDART00000137131
dnah7
dynein, axonemal, heavy chain 7
chr17_-_30652738 0.16 ENSDART00000154960
sh3yl1
SH3 and SYLF domain containing 1
chr2_-_14387335 0.16 ENSDART00000189332
ENSDART00000164786
ENSDART00000188572
sgip1b
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr9_-_41040492 0.16 ENSDART00000163164
adat3
adenosine deaminase, tRNA-specific 3
chr16_+_29514473 0.16 ENSDART00000034102
ctss2.2
cathepsin S, ortholog 2, tandem duplicate 2
chr16_+_4838808 0.15 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr8_-_23612462 0.15 ENSDART00000025024
slc38a5b
solute carrier family 38, member 5b
chr17_-_22552678 0.15 ENSDART00000079401
si:ch211-125o16.4
si:ch211-125o16.4
chr19_-_43004356 0.15 ENSDART00000098101
zcchc17
zinc finger, CCHC domain containing 17
chr20_+_492529 0.15 ENSDART00000141709
FO904980.1

chr21_+_43400351 0.15 ENSDART00000141098
frmd7
FERM domain containing 7
chr11_-_12471837 0.15 ENSDART00000113175
ENSDART00000186965
si:dkey-27d5.6
si:dkey-27d5.6
chr20_+_34151670 0.14 ENSDART00000152870
ENSDART00000010329
ENSDART00000145852
arpc5b
actin related protein 2/3 complex, subunit 5B
chr17_+_7513673 0.14 ENSDART00000156674
klhl10b.1
kelch-like family member 10b, tandem duplicate 1
chr21_-_17016788 0.14 ENSDART00000186703
AL844518.1

chr18_+_30370559 0.14 ENSDART00000165450
gse1
Gse1 coiled-coil protein
chr15_-_45246911 0.14 ENSDART00000189557
ENSDART00000185291
CABZ01072607.1

chr25_+_28893615 0.14 ENSDART00000156994
ENSDART00000075151
amn1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr10_-_44482911 0.14 ENSDART00000085556
hip1ra
huntingtin interacting protein 1 related a
chr23_-_19051710 0.14 ENSDART00000111852
arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr8_+_8196087 0.14 ENSDART00000026965
plxnb3
plexin B3
chr5_+_27137473 0.14 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr6_+_19948043 0.14 ENSDART00000182636
pik3r5
phosphoinositide-3-kinase, regulatory subunit 5
chr13_+_21677767 0.13 ENSDART00000165166
mtg1
mitochondrial ribosome-associated GTPase 1
chr15_-_41708657 0.13 ENSDART00000154384
si:ch211-276c2.4
si:ch211-276c2.4
chr11_+_11430725 0.13 ENSDART00000188040
si:dkey-23f9.11
si:dkey-23f9.11
chr4_-_25812329 0.13 ENSDART00000146658
tmcc3
transmembrane and coiled-coil domain family 3
chr4_+_612363 0.13 ENSDART00000049154
pthlha
parathyroid hormone-like hormone a
chr2_+_42005217 0.13 ENSDART00000143562
gbp2
guanylate binding protein 2
chr25_+_7591293 0.13 ENSDART00000130416
FO704779.1

chr21_-_17016105 0.12 ENSDART00000189120
AL844518.1

chr21_-_11970199 0.12 ENSDART00000114524
nop56
NOP56 ribonucleoprotein homolog
chr19_-_20162980 0.12 ENSDART00000184605
fam221a
family with sequence similarity 221, member A
chr7_-_1101694 0.11 ENSDART00000183017
ENSDART00000182681
dctn1a
dynactin 1a
chr4_-_25515154 0.11 ENSDART00000186524
rbm17
RNA binding motif protein 17
chr5_-_20205075 0.11 ENSDART00000051611
dao.3
D-amino-acid oxidase, tandem duplicate 3
chr23_-_19051869 0.11 ENSDART00000140866
arfgef2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr10_-_36721726 0.11 ENSDART00000122132
pimr137
Pim proto-oncogene, serine/threonine kinase, related 137
chr3_-_52674089 0.11 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
si:dkey-210j14.4
chr22_-_817479 0.11 ENSDART00000123487
zgc:153675
zgc:153675
chr24_+_26887487 0.11 ENSDART00000189425
CR376848.1

chr7_+_16509201 0.10 ENSDART00000173777
zdhhc13
zinc finger, DHHC-type containing 13
chr5_+_51026563 0.10 ENSDART00000050988
gcnt4a
glucosaminyl (N-acetyl) transferase 4, core 2, a
chr23_+_32101361 0.10 ENSDART00000138849
zgc:56699
zgc:56699
chr8_+_20438884 0.10 ENSDART00000016422
ENSDART00000133794
mknk2b
MAP kinase interacting serine/threonine kinase 2b
chr10_+_14210667 0.10 ENSDART00000138854
si:dkey-286h21.1
si:dkey-286h21.1
chr23_+_45282858 0.10 ENSDART00000162353
CABZ01073265.1

chr16_-_24819860 0.10 ENSDART00000183874
kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr15_+_36966369 0.09 ENSDART00000163622
kirrel3l
kirre like nephrin family adhesion molecule 3, like
chr10_-_43568239 0.09 ENSDART00000131731
ENSDART00000097433
ENSDART00000131309
mef2ca
myocyte enhancer factor 2ca
chr6_+_11249706 0.09 ENSDART00000186547
ENSDART00000193287
atg9a
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr9_+_25776971 0.09 ENSDART00000146011
zeb2a
zinc finger E-box binding homeobox 2a
chr9_-_16853462 0.09 ENSDART00000160273
CT573248.2

chr11_-_12350237 0.09 ENSDART00000191094
si:dkey-27d5.14
si:dkey-27d5.14
chr9_-_2892250 0.09 ENSDART00000140695
cdca7a
cell division cycle associated 7a
chr23_+_21278948 0.08 ENSDART00000156701
ENSDART00000033970
ubr4
ubiquitin protein ligase E3 component n-recognin 4
chr18_-_48558420 0.08 ENSDART00000058987
kcnj1a.1
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr6_+_12865137 0.08 ENSDART00000090065
fam117ba
family with sequence similarity 117, member Ba
chr20_+_18551657 0.08 ENSDART00000147001
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr20_+_42563618 0.08 ENSDART00000153441
igf2r
insulin-like growth factor 2 receptor
chr15_+_5132439 0.08 ENSDART00000010350
pgm2l1
phosphoglucomutase 2-like 1
chr23_-_43486714 0.08 ENSDART00000169726
e2f1
E2F transcription factor 1
chr4_+_3455146 0.08 ENSDART00000180124
znf800b
zinc finger protein 800b
chr24_+_9003998 0.07 ENSDART00000179656
ENSDART00000191314
CR318624.2

chr15_+_32268790 0.07 ENSDART00000154457
fhdc4
FH2 domain containing 4
chr9_-_21918963 0.07 ENSDART00000090782
lmo7a
LIM domain 7a
chr20_+_23173710 0.07 ENSDART00000074172
sgcb
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr23_+_36095260 0.07 ENSDART00000127384
hoxc9a
homeobox C9a
chr4_-_22311610 0.07 ENSDART00000137814
hcls1
hematopoietic cell-specific Lyn substrate 1
chr9_-_2892045 0.07 ENSDART00000137201
cdca7a
cell division cycle associated 7a
chr1_-_2457546 0.07 ENSDART00000103795
ggact.1
gamma-glutamylamine cyclotransferase, tandem duplicate 1
chr11_+_24620742 0.06 ENSDART00000182471
ENSDART00000048365
syt6b
synaptotagmin VIb
chr15_-_1038193 0.06 ENSDART00000159462
si:dkey-77f5.3
si:dkey-77f5.3
chr16_+_20926673 0.06 ENSDART00000009827
hoxa2b
homeobox A2b
chr14_-_25577094 0.06 ENSDART00000163669
cplx2
complexin 2
chr13_+_10970614 0.06 ENSDART00000058147
dync2li1
dynein, cytoplasmic 2, light intermediate chain 1
chr6_+_20647155 0.06 ENSDART00000193477
slc19a1
solute carrier family 19 (folate transporter), member 1
chr25_-_28768489 0.06 ENSDART00000088315
washc4
WASH complex subunit 4
chr22_+_10010292 0.06 ENSDART00000180096
BX324216.4

chr10_+_24631976 0.06 ENSDART00000181928
slc46a3
solute carrier family 46, member 3
chr11_+_25276748 0.05 ENSDART00000126211
cyldb
cylindromatosis (turban tumor syndrome), b
chr7_-_31441420 0.05 ENSDART00000075398
cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr7_-_22941472 0.05 ENSDART00000190334
tnfsf10l
TNF superfamily member 10, like
chr7_+_53152108 0.05 ENSDART00000171350
cdh29
cadherin 29

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx8a+lhx8b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.6 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.4 GO:0030238 male sex determination(GO:0030238)
0.1 0.3 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 1.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.1 1.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0071387 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.1 0.6 GO:0032475 otolith formation(GO:0032475)
0.1 0.9 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.4 GO:0045117 azole transport(GO:0045117)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607) nuclear pore organization(GO:0006999)
0.0 0.4 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.1 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712) ectodermal cell fate specification(GO:0001715) ectodermal cell differentiation(GO:0010668) regulation of ectodermal cell fate specification(GO:0042665) regulation of ectoderm development(GO:2000383)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.3 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.6 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.2 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:0060021 palate development(GO:0060021)
0.0 0.4 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:0035476 angioblast cell migration(GO:0035476)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 0.6 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.2 GO:0097268 cytoophidium(GO:0097268)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.3 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0005903 brush border(GO:0005903)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 0.6 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.1 0.4 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 1.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.3 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.2 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.9 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 1.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.3 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery