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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mafaa

Z-value: 0.25

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Transcription factors associated with mafaa

Gene Symbol Gene ID Gene Info
ENSDARG00000044155 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafaadr11_v1_chr6_-_32703317_32703317-0.772.1e-04Click!

Activity profile of mafaa motif

Sorted Z-values of mafaa motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_19596214 0.85 ENSDART00000183110

chr5_-_33230794 0.47 ENSDART00000144273
KN motif and ankyrin repeat domains 1b
chr6_-_33913184 0.41 ENSDART00000146373
nuclear autoantigenic sperm protein (histone-binding)
chr12_+_30789611 0.36 ENSDART00000181501
aldehyde dehydrogenase 18 family, member A1
chr7_+_27603211 0.33 ENSDART00000148782
cytochrome P450, family 2, subfamily R, polypeptide 1
chr21_-_17037907 0.25 ENSDART00000101263
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr17_-_20202725 0.25 ENSDART00000133650
ecdysoneless homolog (Drosophila)
chr9_-_1639884 0.22 ENSDART00000062850
ENSDART00000150947
alkylglycerone phosphate synthase
chr22_+_5574952 0.21 ENSDART00000171774
zgc:171566
chr13_-_50463938 0.18 ENSDART00000083857
cyclin J
chr5_-_23795688 0.17 ENSDART00000099084
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr19_-_48010490 0.16 ENSDART00000159938
zgc:158376
chr15_-_17138640 0.15 ENSDART00000080777
mitochondrial ribosomal protein L28
chr7_-_40578733 0.14 ENSDART00000173926
ENSDART00000010035
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr24_-_38079261 0.14 ENSDART00000105662
C-reactive protein 1
chr1_-_26045007 0.14 ENSDART00000129259
G patch domain and ankyrin repeats 1
chr5_-_5326010 0.14 ENSDART00000161946
pre-B-cell leukemia homeobox 3a
chr2_-_57707039 0.13 ENSDART00000097685

chr25_+_3217419 0.12 ENSDART00000104859
RCC1 domain containing 1
chr2_-_37465517 0.12 ENSDART00000139983
si:dkey-57k2.6
chr25_-_4235037 0.12 ENSDART00000093003
synaptotagmin VIIa
chr21_-_1642739 0.11 ENSDART00000151118
zgc:152948
chr4_-_14486822 0.11 ENSDART00000048821
plexin b2a
chr24_+_37709191 0.11 ENSDART00000066558
2,4-dienoyl CoA reductase 2, peroxisomal
chr8_-_21071711 0.10 ENSDART00000111600
ENSDART00000135204
ENSDART00000131371
ENSDART00000146532
ENSDART00000137606
zgc:112962
chr8_-_21071476 0.10 ENSDART00000184184
ENSDART00000100288
zgc:112962
chr10_-_2788668 0.10 ENSDART00000131749
ENSDART00000124356
ENSDART00000085031
ash2 (absent, small, or homeotic)-like (Drosophila)
chr4_-_58448785 0.09 ENSDART00000172359
si:ch211-212k5.3
chr6_+_42475730 0.09 ENSDART00000150226
macrophage stimulating 1 receptor a
chr12_-_19119176 0.08 ENSDART00000149180
aconitase 2, mitochondrial
chr14_-_30490763 0.08 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
mitochondrial calcium uptake family, member 3b
chr6_-_25371196 0.08 ENSDART00000187291
zgc:153916
chr17_-_14966384 0.08 ENSDART00000105064
thioredoxin domain containing 16
chr24_+_80653 0.08 ENSDART00000158473
ENSDART00000129135
reversion-inducing-cysteine-rich protein with kazal motifs
chr6_-_13709591 0.08 ENSDART00000151771
chondroitin polymerizing factor b
chr7_-_7493758 0.07 ENSDART00000036703
prefoldin subunit 2
chr11_+_12719944 0.07 ENSDART00000054837
ENSDART00000144954
adaptor-related protein complex 1, sigma 2 subunit
chr20_+_54323218 0.07 ENSDART00000191096

chr12_+_12789853 0.07 ENSDART00000064839
glutamate receptor, ionotropic, delta 1b
chr16_-_27676123 0.06 ENSDART00000180804
transforming growth factor beta regulator 4
chr25_+_459901 0.06 ENSDART00000154895
protogenin homolog b (Gallus gallus)
chr25_-_24240797 0.05 ENSDART00000132790
SPT2 chromatin protein domain containing 1
chr19_-_3777217 0.05 ENSDART00000160510
si:dkey-206d17.15
chr1_+_52392511 0.05 ENSDART00000144025
si:ch211-217k17.8
chr11_+_6115621 0.05 ENSDART00000165031
ENSDART00000027666
ENSDART00000161458
nuclear receptor subfamily 2, group F, member 6b
chr20_-_14321359 0.04 ENSDART00000145104
discs, large (Drosophila) homolog-associated protein 2b
chr7_+_41421998 0.04 ENSDART00000083967
chondroitin polymerizing factor 2
chr16_+_42465518 0.04 ENSDART00000058699
si:ch211-215k15.4
chr16_+_4658250 0.04 ENSDART00000006212
si:ch1073-284b18.2
chr13_-_28272299 0.04 ENSDART00000006393
T cell leukemia homeobox 1
chr16_+_1353894 0.04 ENSDART00000148426
cugbp, Elav-like family member 3b
chr5_-_35137365 0.04 ENSDART00000141218
FCH domain only 2
chr3_-_10677890 0.04 ENSDART00000155382
ENSDART00000171319
si:ch1073-144j5.2
chr18_+_33591704 0.04 ENSDART00000185631
ENSDART00000057845
si:dkey-47k20.5
chr8_+_9699111 0.03 ENSDART00000111853
GRIP1 associated protein 1
chr5_+_51102010 0.03 ENSDART00000110377
zgc:194398
chr23_+_3538463 0.03 ENSDART00000172758
si:dkey-9l20.3
chr22_-_27709692 0.03 ENSDART00000172458

chr12_+_40905427 0.03 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
cadherin 18
chr15_+_26940569 0.03 ENSDART00000189636
ENSDART00000077172
breast carcinoma amplified sequence 3
chr23_+_12916062 0.03 ENSDART00000144268
si:dkey-150i13.2
chr4_+_19700308 0.03 ENSDART00000027919
paired box 4
chr4_+_9911534 0.03 ENSDART00000109452
SET binding factor 1
chr1_-_16676177 0.03 ENSDART00000159038
FSHD region gene 1
chr8_-_14052349 0.02 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr25_-_27842654 0.02 ENSDART00000154852
ENSDART00000156906
ankyrin repeat and SOCS box containing 15a
chr24_+_6353394 0.02 ENSDART00000165118

chr3_-_62417677 0.02 ENSDART00000101888
somatostatin receptor 2b
chr13_+_6295173 0.02 ENSDART00000163855
angiopoietin 2a
chr4_-_50926767 0.02 ENSDART00000183430
si:ch211-208f21.3
chr1_+_59090583 0.02 ENSDART00000150658
microfibril associated protein 4
chr15_-_18432673 0.02 ENSDART00000146853
neural cell adhesion molecule 1b
chr13_+_4671698 0.02 ENSDART00000164617
ENSDART00000128494
ENSDART00000165776
phospholipase A2, group XIIB
chr8_-_3336273 0.01 ENSDART00000081160
zgc:173737
chr16_-_46567344 0.01 ENSDART00000127721
si:dkey-152b24.7
chr6_-_131401 0.01 ENSDART00000151251
si:zfos-323e3.4
chr3_-_1388936 0.01 ENSDART00000171278
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr11_+_25276748 0.01 ENSDART00000126211
cylindromatosis (turban tumor syndrome), b
chr13_-_301309 0.01 ENSDART00000131747
chitin synthase 1
chr1_+_59090743 0.01 ENSDART00000100199
microfibril associated protein 4
chr25_-_3217115 0.01 ENSDART00000032390
general transcription factor IIH, polypeptide 1
chr22_-_775776 0.01 ENSDART00000149749
retinoblastoma binding protein 5
chr3_-_34055745 0.00 ENSDART00000151652
immunoglobulin heavy variable 2-2
chr1_+_59090972 0.00 ENSDART00000171497
microfibril associated protein 4

Network of associatons between targets according to the STRING database.

First level regulatory network of mafaa

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.1 0.3 GO:0070640 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.0 0.4 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0003994 aconitate hydratase activity(GO:0003994)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type