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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for maza+mazb

Z-value: 1.18

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Transcription factors associated with maza+mazb

Gene Symbol Gene ID Gene Info
mazb
ENSDARG00000063555 si_ch211-166g5.4
maza
ENSDARG00000087330 MYC-associated zinc finger protein a (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mazadr11_v1_chr3_-_21118969_21118969-0.984.9e-13Click!
si:ch211-166g5.4dr11_v1_chr12_-_3778848_37788480.484.2e-02Click!

Activity profile of maza+mazb motif

Sorted Z-values of maza+mazb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_44183613 7.00 ENSDART00000079596
cadm3
cell adhesion molecule 3
chr2_-_44183451 6.45 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr24_+_31361407 4.11 ENSDART00000162668
cremb
cAMP responsive element modulator b
chr10_-_641609 3.61 ENSDART00000041236
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr20_-_7080427 2.63 ENSDART00000140166
ENSDART00000023677
si:ch211-121a2.2
si:ch211-121a2.2
chr3_+_32425202 2.57 ENSDART00000156464
prr12b
proline rich 12b
chr6_+_59029485 1.90 ENSDART00000050140
CABZ01088367.1

chr17_-_4395373 1.90 ENSDART00000015923
klhl10a
kelch-like family member 10a
chr25_+_1732838 1.87 ENSDART00000159555
ENSDART00000168161
FBLN1
fibulin 1
chr21_+_13577227 1.83 ENSDART00000146283
si:dkey-248f6.3
si:dkey-248f6.3
chr2_+_22694382 1.80 ENSDART00000139196
kif1ab
kinesin family member 1Ab
chr10_-_27197044 1.76 ENSDART00000137928
auts2a
autism susceptibility candidate 2a
chr23_+_19691146 1.75 ENSDART00000143001
si:dkey-93l1.6
si:dkey-93l1.6
chr15_+_19838458 1.72 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr13_+_37022601 1.71 ENSDART00000131800
ENSDART00000041300
esr2b
estrogen receptor 2b
chr5_-_22619879 1.60 ENSDART00000051623
zgc:113208
zgc:113208
chr19_-_35035857 1.60 ENSDART00000103253
bmp8a
bone morphogenetic protein 8a
chr2_-_43168292 1.57 ENSDART00000132588
crema
cAMP responsive element modulator a
chr23_-_19140781 1.55 ENSDART00000143580
si:ch73-381f5.2
si:ch73-381f5.2
chr1_-_39943596 1.54 ENSDART00000149730
stox2a
storkhead box 2a
chr2_-_24907741 1.51 ENSDART00000155013
si:dkey-149i17.11
si:dkey-149i17.11
chr12_-_26851726 1.49 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr14_-_9522364 1.48 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr4_-_16406737 1.48 ENSDART00000013085
dcn
decorin
chr23_+_19182819 1.47 ENSDART00000131804
si:dkey-93l1.4
si:dkey-93l1.4
chr16_+_10918252 1.43 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr3_-_16289826 1.43 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr5_-_30715225 1.37 ENSDART00000016758
ftr82
finTRIM family, member 82
chr17_+_43889371 1.36 ENSDART00000156871
ENSDART00000154702
msh4
mutS homolog 4
chr3_+_60721342 1.36 ENSDART00000157772
foxj1a
forkhead box J1a
chr16_-_23800484 1.34 ENSDART00000139964
rps27.2
ribosomal protein S27, isoform 2
chr4_-_8060962 1.33 ENSDART00000146622
wnk1b
WNK lysine deficient protein kinase 1b
chr7_+_528593 1.33 ENSDART00000091955
nrxn2b
neurexin 2b
chr21_-_43015383 1.33 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr20_-_48516765 1.32 ENSDART00000150200
si:zfos-223e1.2
si:zfos-223e1.2
chr7_+_44713135 1.31 ENSDART00000170721
si:dkey-56m19.5
si:dkey-56m19.5
chr12_-_10705916 1.29 ENSDART00000164038
FO704786.1

chr13_+_41022502 1.26 ENSDART00000026808
dkk1a
dickkopf WNT signaling pathway inhibitor 1a
chr1_-_38709551 1.26 ENSDART00000128794
gpm6ab
glycoprotein M6Ab
chr11_-_11518469 1.24 ENSDART00000104254
krt15
keratin 15
chr5_-_68022631 1.23 ENSDART00000143199
wasf3a
WAS protein family, member 3a
chr10_+_10210455 1.23 ENSDART00000144214
sh2d3ca
SH2 domain containing 3Ca
chr20_-_14875308 1.23 ENSDART00000141290
dnm3a
dynamin 3a
chr16_+_7662609 1.22 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
bves
blood vessel epicardial substance
chr21_-_43117327 1.22 ENSDART00000122352
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr19_+_9533008 1.22 ENSDART00000104607
fam131ba
family with sequence similarity 131, member Ba
chr1_-_19402802 1.21 ENSDART00000135552
rbm47
RNA binding motif protein 47
chr10_-_5857548 1.19 ENSDART00000166933
si:ch211-281k19.2
si:ch211-281k19.2
chr18_+_21122818 1.18 ENSDART00000060015
ENSDART00000060184
chka
choline kinase alpha
chr2_-_32501501 1.16 ENSDART00000181309
faim2a
Fas apoptotic inhibitory molecule 2a
chr19_-_10043142 1.15 ENSDART00000193016
grin2da
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a
chr4_-_17055782 1.15 ENSDART00000134595
sox5
SRY (sex determining region Y)-box 5
chr17_-_26926577 1.14 ENSDART00000050202
rcan3
regulator of calcineurin 3
chr10_-_44026369 1.12 ENSDART00000185456
crybb1
crystallin, beta B1
chr14_+_30730749 1.11 ENSDART00000087884
ccdc85b
coiled-coil domain containing 85B
chr15_-_5742531 1.08 ENSDART00000045985
phkg1a
phosphorylase kinase, gamma 1a (muscle)
chr4_-_8058214 1.08 ENSDART00000132228
wnk1b
WNK lysine deficient protein kinase 1b
chr10_-_31563049 1.07 ENSDART00000023575
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr22_+_2860260 1.04 ENSDART00000106221
si:dkey-20i20.2
si:dkey-20i20.2
chr22_-_17729778 1.02 ENSDART00000192132
si:ch73-63e15.2
si:ch73-63e15.2
chr12_-_684200 1.00 ENSDART00000152122
si:ch211-176g6.2
si:ch211-176g6.2
chr1_+_12009673 1.00 ENSDART00000080100
slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr15_-_30450898 0.99 ENSDART00000156584
msi2b
musashi RNA-binding protein 2b
chr9_+_12907574 0.98 ENSDART00000102348
si:dkey-230p4.1
si:dkey-230p4.1
chr20_+_18740518 0.98 ENSDART00000142196
fam167ab
family with sequence similarity 167, member Ab
chr6_-_43922813 0.97 ENSDART00000123341
prok2
prokineticin 2
chr17_+_26783828 0.97 ENSDART00000154921
larp1b
La ribonucleoprotein domain family, member 1B
chr1_-_58562129 0.97 ENSDART00000159070
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr14_-_36862745 0.96 ENSDART00000109293
rnf130
ring finger protein 130
chr11_-_11471857 0.95 ENSDART00000030103
krt94
keratin 94
chr7_-_24236364 0.94 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr7_+_36552725 0.94 ENSDART00000173682
chd9
chromodomain helicase DNA binding protein 9
chr7_+_19552381 0.93 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr5_+_38263240 0.91 ENSDART00000051231
gnb2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr7_-_10606 0.91 ENSDART00000192650
ENSDART00000186761
FO704772.2

chr7_-_24995631 0.91 ENSDART00000173955
ENSDART00000173791
rcor2
REST corepressor 2
chr24_+_42127983 0.90 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr19_+_4912817 0.90 ENSDART00000101658
ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr24_-_28243186 0.89 ENSDART00000105691
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr23_-_40796992 0.89 ENSDART00000145116
si:dkey-194e6.2
si:dkey-194e6.2
chr18_+_44649804 0.88 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr7_+_46261199 0.88 ENSDART00000170390
ENSDART00000183227
znf536
zinc finger protein 536
chr13_-_31435137 0.88 ENSDART00000057441
rtn1a
reticulon 1a
chr20_-_26420939 0.87 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr2_+_24931677 0.86 ENSDART00000021528
agtr1a
angiotensin II receptor, type 1a
chr14_+_24283915 0.86 ENSDART00000172868
klhl3
kelch-like family member 3
chr18_-_2668698 0.84 ENSDART00000157510
relt
RELT, TNF receptor
chr5_+_37087583 0.84 ENSDART00000049900
tagln2
transgelin 2
chr7_+_26029672 0.83 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr17_+_32500387 0.83 ENSDART00000018423
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr24_+_42132962 0.83 ENSDART00000187739
wwp1
WW domain containing E3 ubiquitin protein ligase 1
chr3_-_57425961 0.79 ENSDART00000033716
socs3a
suppressor of cytokine signaling 3a
chr24_+_3050020 0.79 ENSDART00000004241
inhbaa
inhibin, beta Aa
chr2_-_23479714 0.79 ENSDART00000167291
si:ch211-14p21.3
si:ch211-14p21.3
chr15_-_20024205 0.79 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr4_+_20255160 0.78 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr20_-_26421112 0.78 ENSDART00000183767
ENSDART00000182330
akap12b
A kinase (PRKA) anchor protein 12b
chr7_+_39401388 0.78 ENSDART00000144750
tnni2b.1
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr23_-_40817792 0.77 ENSDART00000136343
si:dkeyp-27c8.1
si:dkeyp-27c8.1
chr14_-_1990290 0.75 ENSDART00000183382
pcdh2g5
protocadherin 2 gamma 5
chr4_-_68569527 0.74 ENSDART00000192091
BX548011.5

chr20_+_20672163 0.74 ENSDART00000027758
rtn1b
reticulon 1b
chr18_-_15911394 0.74 ENSDART00000091339
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr4_-_9764767 0.73 ENSDART00000164328
ENSDART00000147699
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr1_-_58561963 0.72 ENSDART00000165040
slc27a1b
solute carrier family 27 (fatty acid transporter), member 1b
chr21_-_9991502 0.72 ENSDART00000169320
esm1
endothelial cell-specific molecule 1
chr9_-_32912638 0.72 ENSDART00000110582
fam160a2
family with sequence similarity 160, member A2
chr25_-_12788370 0.70 ENSDART00000158551
slc7a5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr8_-_36554675 0.70 ENSDART00000132804
ENSDART00000078746
ccdc157
coiled-coil domain containing 157
chr11_-_38928760 0.70 ENSDART00000146277
si:ch211-122l14.6
si:ch211-122l14.6
chr4_-_26108053 0.70 ENSDART00000066951
si:ch211-244b2.4
si:ch211-244b2.4
chr3_+_14388010 0.69 ENSDART00000171726
ENSDART00000165452
tmem56b
transmembrane protein 56b
chr7_+_24888910 0.69 ENSDART00000173994
mark2b
MAP/microtubule affinity-regulating kinase 2b
chr17_+_26569601 0.69 ENSDART00000153897
ndnfl
neuron-derived neurotrophic factor , like
chr13_-_45523026 0.68 ENSDART00000020663
rhd
Rh blood group, D antigen
chr3_-_39152478 0.68 ENSDART00000154550
si:dkeyp-57f11.2
si:dkeyp-57f11.2
chr21_-_32684570 0.68 ENSDART00000162873
adamts2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr6_+_9651703 0.68 ENSDART00000122937
tcf23
transcription factor 23
chr16_+_23431189 0.67 ENSDART00000004679
icn
ictacalcin
chr20_+_6630540 0.67 ENSDART00000138361
tns3.2
tensin 3, tandem duplicate 2
chr21_+_41649336 0.67 ENSDART00000164694
ENSDART00000181539
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr1_-_19502322 0.67 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr2_-_23443189 0.66 ENSDART00000168894
si:ch211-14p21.4
si:ch211-14p21.4
chr6_-_442163 0.66 ENSDART00000163564
ENSDART00000189134
ENSDART00000169789
grap2b
GRB2-related adaptor protein 2b
chr23_-_40779334 0.66 ENSDART00000141432
DUPD1 (1 of many)
si:dkeyp-27c8.1
chr3_-_23643751 0.66 ENSDART00000078425
ENSDART00000140264
eve1
even-skipped-like1
chr4_+_5537101 0.65 ENSDART00000008692
si:dkey-14d8.7
si:dkey-14d8.7
chr4_-_17055950 0.65 ENSDART00000162945
sox5
SRY (sex determining region Y)-box 5
chr2_+_31597841 0.65 ENSDART00000162181
si:ch211-106h4.4
si:ch211-106h4.4
chr24_-_4450238 0.65 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr6_+_39836474 0.65 ENSDART00000112637
smarcc2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr22_+_16418688 0.64 ENSDART00000009360
ankrd29
ankyrin repeat domain 29
chr8_+_22931427 0.64 ENSDART00000063096
sypa
synaptophysin a
chr7_-_41468942 0.63 ENSDART00000174087
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr3_-_22212764 0.63 ENSDART00000155490
maptb
microtubule-associated protein tau b
chr4_-_26107841 0.62 ENSDART00000172012
si:ch211-244b2.4
si:ch211-244b2.4
chr14_-_42231293 0.62 ENSDART00000185486
BX890543.1

chr14_-_2602445 0.62 ENSDART00000166910
etf1a
eukaryotic translation termination factor 1a
chr3_-_33417826 0.62 ENSDART00000084284
abi3a
ABI family, member 3a
chr8_-_11229523 0.61 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr2_+_21486529 0.61 ENSDART00000047468
inhbab
inhibin, beta Ab
chr8_+_39802506 0.59 ENSDART00000018862
hnf1a
HNF1 homeobox a
chr17_-_43287290 0.58 ENSDART00000156885
EML5
si:dkey-1f12.3
chr10_+_34394454 0.58 ENSDART00000110121
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr12_-_31009315 0.57 ENSDART00000133854
tcf7l2
transcription factor 7 like 2
chr20_+_33875256 0.57 ENSDART00000002554
rxrgb
retinoid X receptor, gamma b
chr21_+_45841731 0.55 ENSDART00000038657
faxdc2
fatty acid hydroxylase domain containing 2
chr12_-_45349849 0.54 ENSDART00000183036
CABZ01068367.1
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr12_-_34887943 0.54 ENSDART00000027379
bicral
BRD4 interacting chromatin remodeling complex associated protein like
chr11_-_3334248 0.54 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr8_+_8947623 0.54 ENSDART00000131215
slc35a2
solute carrier family 35 (UDP-galactose transporter), member 2
chr6_+_6850821 0.53 ENSDART00000166607
ENSDART00000111024
zgc:171558
zgc:171558
chr23_+_14217508 0.53 ENSDART00000143618
birc7
baculoviral IAP repeat containing 7
chr25_-_11088839 0.53 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr3_-_30625219 0.52 ENSDART00000151698
syt3
synaptotagmin III
chr9_-_39968820 0.52 ENSDART00000100311
IKZF2
si:zfos-1425h8.1
chr20_-_21672970 0.51 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr5_-_14344647 0.51 ENSDART00000188456
tet3
tet methylcytosine dioxygenase 3
chr2_-_23411368 0.51 ENSDART00000159495
si:ch73-129a22.11
si:ch73-129a22.11
chr4_+_8680767 0.51 ENSDART00000182726
adipor2
adiponectin receptor 2
chr15_+_47903864 0.51 ENSDART00000063835
otx5
orthodenticle homolog 5
chr5_+_57641554 0.51 ENSDART00000171309
ENSDART00000157992
ENSDART00000164742
cryabb
crystallin, alpha B, b
chr6_-_42418225 0.51 ENSDART00000002501
ip6k2a
inositol hexakisphosphate kinase 2a
chr16_-_9802449 0.50 ENSDART00000081208
tapbpl
TAP binding protein (tapasin)-like
chr19_-_8600383 0.50 ENSDART00000081546
trim46b
tripartite motif containing 46b
chr21_+_16980141 0.50 ENSDART00000101241
aqp3b
aquaporin 3b
chr11_-_22303678 0.50 ENSDART00000159527
ENSDART00000159681
tfeb
transcription factor EB
chr17_-_8976307 0.49 ENSDART00000092113
zranb1b
zinc finger, RAN-binding domain containing 1b
chr10_-_31562695 0.49 ENSDART00000186456
robo3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr4_-_16545085 0.49 ENSDART00000033188
btg1
B-cell translocation gene 1, anti-proliferative
chr21_-_25748913 0.48 ENSDART00000134217
CR388166.2

chr11_-_41130239 0.48 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr17_+_53418445 0.47 ENSDART00000097631
slc9a1b
solute carrier family 9 member A1b
chr4_+_20263097 0.47 ENSDART00000138820
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr5_-_16351306 0.47 ENSDART00000168643
CABZ01088700.1

chr10_-_22803740 0.46 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr14_-_16423200 0.46 ENSDART00000108868
ENSDART00000161793
maml1
mastermind-like transcriptional coactivator 1
chr5_-_67661102 0.46 ENSDART00000013605
zbtb20
zinc finger and BTB domain containing 20
chr12_-_34459601 0.46 ENSDART00000111717
fscn2b
fascin actin-bundling protein 2b, retinal
chr2_-_56095275 0.46 ENSDART00000154701
si:ch211-178n15.1
si:ch211-178n15.1
chr11_-_11878099 0.46 ENSDART00000188314
wipf2a
WAS/WASL interacting protein family, member 2a
chr2_+_24781026 0.45 ENSDART00000145692
pde4ca
phosphodiesterase 4C, cAMP-specific a
chr19_-_27777228 0.45 ENSDART00000046166
adcy2b
adenylate cyclase 2b (brain)
chr14_-_25577094 0.45 ENSDART00000163669
cplx2
complexin 2
chr21_+_26697536 0.45 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr15_-_37543591 0.44 ENSDART00000180400
kmt2bb
lysine (K)-specific methyltransferase 2Bb
chr13_+_771403 0.43 ENSDART00000093166
nrxn1b
neurexin 1b
chr1_-_49225890 0.43 ENSDART00000111598
cxcl18b
chemokine (C-X-C motif) ligand 18b
chr8_+_32516160 0.43 ENSDART00000061786
ncs1b
neuronal calcium sensor 1b
chr3_+_36284986 0.43 ENSDART00000059533
wipi1
WD repeat domain, phosphoinositide interacting 1
chr12_+_27061720 0.43 ENSDART00000153426
srcap
Snf2-related CREBBP activator protein
chr2_+_33052360 0.43 ENSDART00000134651
rnf220a
ring finger protein 220a
chr11_+_37137196 0.43 ENSDART00000172950
wnk2
WNK lysine deficient protein kinase 2
chr3_+_6469754 0.42 ENSDART00000185809
NUP85 (1 of many)
nucleoporin 85
chr10_+_33895315 0.42 ENSDART00000142881
fryb
furry homolog b (Drosophila)
chr13_-_50139916 0.42 ENSDART00000099475
nid1a
nidogen 1a
chr24_+_13925066 0.41 ENSDART00000134221
ENSDART00000012253
ENSDART00000081595
ENSDART00000136443
eya1
EYA transcriptional coactivator and phosphatase 1
chr19_-_26863626 0.41 ENSDART00000145568
prrt1
proline-rich transmembrane protein 1
chr9_+_38446504 0.41 ENSDART00000077479
cyp27a1.4
cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4
chr11_-_6206520 0.41 ENSDART00000150199
ENSDART00000148246
ENSDART00000019440
pole4
polymerase (DNA-directed), epsilon 4, accessory subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of maza+mazb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.5 1.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.3 1.7 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.3 1.0 GO:0060292 long term synaptic depression(GO:0060292)
0.3 1.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 1.5 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.3 0.9 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.3 1.4 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.3 3.6 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 1.7 GO:0021885 forebrain cell migration(GO:0021885)
0.2 1.2 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.2 0.6 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.2 2.8 GO:1903286 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 1.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 0.7 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.2 0.5 GO:0044107 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.1 0.6 GO:0010226 response to lithium ion(GO:0010226)
0.1 0.4 GO:0003071 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.1 1.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 1.6 GO:0050936 xanthophore differentiation(GO:0050936)
0.1 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.4 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.3 GO:0070293 renal absorption(GO:0070293)
0.1 2.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.5 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.5 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.1 0.3 GO:0055016 hypochord development(GO:0055016)
0.1 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.8 GO:0021884 forebrain neuron development(GO:0021884)
0.1 1.0 GO:0030431 sleep(GO:0030431)
0.1 0.9 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 1.3 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.1 1.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 1.0 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.8 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.7 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 0.3 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1 1.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.3 GO:0071169 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 1.2 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.3 GO:0010481 ventriculo bulbo valve development(GO:0003173) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 2.9 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.3 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.2 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 1.5 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.2 GO:0060074 synapse maturation(GO:0060074)
0.1 0.2 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 0.5 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.3 GO:0003272 endocardial cushion development(GO:0003197) endocardial cushion morphogenesis(GO:0003203) endocardial cushion formation(GO:0003272)
0.0 0.5 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.2 GO:0001843 neural tube closure(GO:0001843)
0.0 0.9 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.5 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.2 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 1.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.3 GO:0021703 locus ceruleus development(GO:0021703)
0.0 0.9 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.9 GO:0019229 regulation of vasoconstriction(GO:0019229)
0.0 0.4 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.3 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 1.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.5 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 8.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.5 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.1 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0001783 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.0 0.2 GO:0036268 swimming(GO:0036268)
0.0 2.1 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.5 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.4 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.2 GO:0008298 cytoplasm organization(GO:0007028) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) intracellular mRNA localization(GO:0008298) maternal determination of anterior/posterior axis, embryo(GO:0008358)
0.0 1.0 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.6 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.5 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.4 GO:0071219 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.0 GO:0048569 post-embryonic organ development(GO:0048569)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.3 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.4 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0021654 rhombomere boundary formation(GO:0021654)
0.0 3.5 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.6 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 1.1 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.4 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.3 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.2 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 1.5 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.7 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.6 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.2 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 1.4 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0016586 RSC complex(GO:0016586)
0.0 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0032019 mitochondrial cloud(GO:0032019)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 0.9 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 2.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0031672 A band(GO:0031672)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.0 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:1903924 estradiol binding(GO:1903924)
0.3 1.3 GO:0039706 co-receptor binding(GO:0039706)
0.2 1.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 0.9 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.2 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 2.8 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.2 1.6 GO:0070700 BMP receptor binding(GO:0070700)
0.2 0.5 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.1 1.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.1 1.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 1.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.6 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 1.9 GO:0051018 protein kinase A binding(GO:0051018)
0.1 1.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.4 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.2 GO:0030552 cAMP binding(GO:0030552)
0.1 0.4 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 1.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 4.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.5 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.2 GO:0098632 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 1.1 GO:0051020 GTPase binding(GO:0051020)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.9 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 2.2 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0042285 xylosyltransferase activity(GO:0042285)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.6 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.4 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0003678 DNA helicase activity(GO:0003678)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.2 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.8 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing