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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mecom

Z-value: 0.48

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Transcription factors associated with mecom

Gene Symbol Gene ID Gene Info
mecom
ENSDARG00000060808 MDS1 and EVI1 complex locus

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecomdr11_v1_chr15_-_35406564_354065640.753.6e-04Click!

Activity profile of mecom motif

Sorted Z-values of mecom motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_19838458 0.77 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr21_-_40799404 0.76 ENSDART00000147405
ENSDART00000157512
zgc:162239
zgc:162239
chr25_+_7571920 0.69 ENSDART00000042928
fuk
fucokinase
chr25_+_25438165 0.68 ENSDART00000161369
LRRC56
si:ch211-103e16.5
chr23_+_13928346 0.67 ENSDART00000155326
si:dkey-90a13.10
si:dkey-90a13.10
chr24_+_31348595 0.66 ENSDART00000160140
ENSDART00000158661
cremb
cAMP responsive element modulator b
chr13_-_11971148 0.63 ENSDART00000066230
ENSDART00000185614
ARL3 (1 of many)
zgc:110197
chr8_+_8893535 0.61 ENSDART00000139150
otud5a
OTU deubiquitinase 5a
chr18_-_17485419 0.57 ENSDART00000018764
foxl1
forkhead box L1
chr14_-_10617127 0.56 ENSDART00000154299
si:dkey-92i17.2
si:dkey-92i17.2
chr16_+_19014886 0.55 ENSDART00000079298
si:ch211-254p10.2
si:ch211-254p10.2
chr2_+_17540720 0.54 ENSDART00000114638
pimr198
Pim proto-oncogene, serine/threonine kinase, related 198
chr8_+_17990195 0.53 ENSDART00000140759
si:dkey-267j14.7
si:dkey-267j14.7
chr2_-_1548330 0.52 ENSDART00000082155
ENSDART00000108481
ENSDART00000111272
dab1b
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr1_+_22003173 0.52 ENSDART00000054388
dnah6
dynein, axonemal, heavy chain 6
chr13_+_9408101 0.51 ENSDART00000091502
si:ch211-243o19.4
si:ch211-243o19.4
chr9_+_48455909 0.50 ENSDART00000167243
lrp2a
low density lipoprotein receptor-related protein 2a
chr7_+_38395197 0.50 ENSDART00000138669
cep89
centrosomal protein 89
chr7_-_24364536 0.50 ENSDART00000064789
txn
thioredoxin
chr1_+_22002649 0.50 ENSDART00000141317
dnah6
dynein, axonemal, heavy chain 6
chr5_-_10946232 0.48 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr21_-_37733287 0.46 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr12_-_6551681 0.46 ENSDART00000145413
si:ch211-253p2.2
si:ch211-253p2.2
chr2_-_43168292 0.46 ENSDART00000132588
crema
cAMP responsive element modulator a
chr4_+_306036 0.46 ENSDART00000103659
msgn1
mesogenin 1
chr1_+_9994811 0.46 ENSDART00000143719
ENSDART00000110749
si:dkeyp-75b4.10
si:dkeyp-75b4.10
chr21_+_6556635 0.45 ENSDART00000139598
col5a1
procollagen, type V, alpha 1
chr10_-_28761454 0.45 ENSDART00000129400
alcama
activated leukocyte cell adhesion molecule a
chr7_-_59054322 0.45 ENSDART00000165390
chmp5b
charged multivesicular body protein 5b
chr6_+_46259950 0.45 ENSDART00000032326
zgc:162324
zgc:162324
chr14_-_32089117 0.44 ENSDART00000158014
si:ch211-69b22.5
si:ch211-69b22.5
chr15_+_42285643 0.44 ENSDART00000152731
scaf4b
SR-related CTD-associated factor 4b
chr25_-_31629095 0.44 ENSDART00000170673
ENSDART00000166930
lamb1a
laminin, beta 1a
chr10_+_9159279 0.43 ENSDART00000064968
rasgef1bb
RasGEF domain family, member 1Bb
chr2_+_17524278 0.43 ENSDART00000165633
pimr196
Pim proto-oncogene, serine/threonine kinase, related 196
chr11_-_14924138 0.43 ENSDART00000168348
si:dkey-6d5.1
si:dkey-6d5.1
chr22_+_11535131 0.43 ENSDART00000113930
npb
neuropeptide B
chr8_-_52715911 0.42 ENSDART00000168241
tubb2b
tubulin, beta 2b
chr16_+_10972733 0.42 ENSDART00000049323
pou2f2a
POU class 2 homeobox 2a
chr7_-_38340674 0.41 ENSDART00000075782
slc7a10a
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10a
chr8_-_28349859 0.41 ENSDART00000062671
tuba8l
tubulin, alpha 8 like
chr22_+_10752511 0.39 ENSDART00000081188
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr16_+_7662609 0.39 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
bves
blood vessel epicardial substance
chr22_+_10752787 0.38 ENSDART00000186542
lsm7
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
chr25_-_7723685 0.38 ENSDART00000146882
phf21ab
PHD finger protein 21Ab
chr17_-_125091 0.38 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr25_+_25438322 0.38 ENSDART00000150364
LRRC56
si:ch211-103e16.5
chr3_-_16289826 0.37 ENSDART00000131972
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr23_+_9220436 0.37 ENSDART00000033663
ENSDART00000139870
rps21
ribosomal protein S21
chr12_-_45197038 0.36 ENSDART00000016635
bccip
BRCA2 and CDKN1A interacting protein
chr22_+_26793389 0.36 ENSDART00000165381
pimr69
Pim proto-oncogene, serine/threonine kinase, related 69
chr3_+_32443395 0.36 ENSDART00000188447
prr12b
proline rich 12b
chr8_-_14179798 0.36 ENSDART00000040645
ENSDART00000146749
rhoaa
ras homolog gene family, member Aa
chr15_+_22311803 0.36 ENSDART00000150182
hepacama
hepatic and glial cell adhesion molecule a
chr24_-_5889878 0.35 ENSDART00000077951
pcolce2b
procollagen C-endopeptidase enhancer 2b
chr19_-_3790595 0.35 ENSDART00000172415
btr18
bloodthirsty-related gene family, member 18
chr5_+_49744713 0.34 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr16_+_4838808 0.33 ENSDART00000179363
ibtk
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr3_-_61116258 0.33 ENSDART00000009194
ENSDART00000156978
aimp2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr13_-_12005429 0.32 ENSDART00000180302
mgea5
meningioma expressed antigen 5 (hyaluronidase)
chr22_+_38301365 0.32 ENSDART00000137339
traf5
Tnf receptor-associated factor 5
chr13_+_28512863 0.31 ENSDART00000043117
fbxw4
F-box and WD repeat domain containing 4
chr3_-_61203203 0.31 ENSDART00000171787
pvalb1
parvalbumin 1
chr3_+_32112004 0.31 ENSDART00000105272
zgc:173593
zgc:173593
chr15_-_23647078 0.30 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr11_+_35364445 0.30 ENSDART00000125766
camkvb
CaM kinase-like vesicle-associated b
chr22_-_17611742 0.30 ENSDART00000144031
gpx4a
glutathione peroxidase 4a
chr20_+_26538137 0.29 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr15_-_32383529 0.29 ENSDART00000028349
c4
complement component 4
chr14_+_52563794 0.28 ENSDART00000168874
rpl26
ribosomal protein L26
chr8_-_31369161 0.28 ENSDART00000019937
gadd45ga
growth arrest and DNA-damage-inducible, gamma a
chr10_-_31782616 0.28 ENSDART00000128839
fez1
fasciculation and elongation protein zeta 1 (zygin I)
chr17_-_15149192 0.28 ENSDART00000180511
ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr21_+_21012210 0.28 ENSDART00000190317
ndr1
nodal-related 1
chr15_+_6652396 0.27 ENSDART00000192813
ENSDART00000157678
nop53
NOP53 ribosome biogenesis factor
chr9_+_13714379 0.27 ENSDART00000017593
ENSDART00000145503
tmem237a
transmembrane protein 237a
chr6_-_40697585 0.27 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr10_-_22854758 0.27 ENSDART00000079449
and3
actinodin3
chr10_-_7988396 0.26 ENSDART00000141445
ENSDART00000024282
ewsr1a
EWS RNA-binding protein 1a
chr18_+_16246806 0.26 ENSDART00000142584
alx1
ALX homeobox 1
chr19_+_16222618 0.25 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
ptprua
protein tyrosine phosphatase, receptor type, U, a
chr10_-_15672862 0.25 ENSDART00000109231
mamdc2b
MAM domain containing 2b
chr11_-_3865472 0.25 ENSDART00000161426
gata2a
GATA binding protein 2a
chr14_+_8725216 0.25 ENSDART00000157630
pimr57
Pim proto-oncogene, serine/threonine kinase, related 57
chr22_-_17256573 0.25 ENSDART00000136119
ENSDART00000062891
nphs2
nephrosis 2, idiopathic, steroid-resistant (podocin)
chr7_+_21887307 0.25 ENSDART00000052871
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr15_+_33991928 0.24 ENSDART00000170177
vwde
von Willebrand factor D and EGF domains
chr12_-_7854216 0.24 ENSDART00000149594
ank3b
ankyrin 3b
chr8_-_38477817 0.24 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr25_-_4148719 0.24 ENSDART00000112880
ENSDART00000023278
fads2
fatty acid desaturase 2
chr11_-_42315748 0.24 ENSDART00000169853
slmapa
sarcolemma associated protein a
chr3_-_32817274 0.24 ENSDART00000142582
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr3_-_7296189 0.23 ENSDART00000148349
si:ch1073-186o8.3
si:ch1073-186o8.3
chr17_-_24521382 0.23 ENSDART00000092948
peli1b
pellino E3 ubiquitin protein ligase 1b
chr25_-_1235457 0.23 ENSDART00000093093
coro2bb
coronin, actin binding protein, 2Bb
chr21_+_7582036 0.23 ENSDART00000135485
ENSDART00000027268
otpa
orthopedia homeobox a
chr25_+_18563476 0.23 ENSDART00000170841
cav1
caveolin 1
chr2_-_51794472 0.23 ENSDART00000186652
BX908782.3

chr5_+_68807170 0.23 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr4_-_685412 0.23 ENSDART00000168167
rtcb
RNA 2',3'-cyclic phosphate and 5'-OH ligase
chr3_-_18792492 0.22 ENSDART00000134208
ENSDART00000034373
hagh
hydroxyacylglutathione hydrolase
chr4_-_12104421 0.22 ENSDART00000139561
mrps33
mitochondrial ribosomal protein S33
chr18_-_21271373 0.22 ENSDART00000060001
pnp6
purine nucleoside phosphorylase 6
chr14_+_35691889 0.22 ENSDART00000074685
glrbb
glycine receptor, beta b
chr7_+_38750871 0.22 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
f2
coagulation factor II (thrombin)
chr20_-_5369105 0.22 ENSDART00000114316
sptlc2b
serine palmitoyltransferase, long chain base subunit 2b
chr6_-_9630081 0.21 ENSDART00000013066
ercc3
excision repair cross-complementation group 3
chr10_+_2899108 0.21 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr25_+_18564266 0.21 ENSDART00000172338
cav1
caveolin 1
chr2_+_29976419 0.21 ENSDART00000056748
en2b
engrailed homeobox 2b
chr23_+_20110086 0.21 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr22_+_14051245 0.21 ENSDART00000043711
ENSDART00000164259
aox6
aldehyde oxidase 6
chr21_-_22317920 0.21 ENSDART00000191083
ENSDART00000108701
gdpd4b
glycerophosphodiester phosphodiesterase domain containing 4b
chr21_+_15704556 0.20 ENSDART00000024858
ENSDART00000146909
chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr11_-_37359416 0.20 ENSDART00000159184
erc2
ELKS/RAB6-interacting/CAST family member 2
chr2_-_24981356 0.20 ENSDART00000111212
nck1a
NCK adaptor protein 1a
chr7_+_24114694 0.20 ENSDART00000127177
mrpl52
mitochondrial ribosomal protein L52
chr16_-_1757521 0.19 ENSDART00000124660
ascc3
activating signal cointegrator 1 complex subunit 3
chr6_+_8176486 0.19 ENSDART00000193308
nfil3-5
nuclear factor, interleukin 3 regulated, member 5
chr9_-_19161982 0.19 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr24_-_36337395 0.19 ENSDART00000154402
si:ch211-40k21.9
si:ch211-40k21.9
chr4_-_73256421 0.19 ENSDART00000174158
CABZ01021433.1

chr22_-_29242347 0.19 ENSDART00000040761
pvalb7
parvalbumin 7
chr3_-_18575868 0.19 ENSDART00000122968
aqp8b
aquaporin 8b
chr24_+_23742690 0.18 ENSDART00000130162
TCF24
transcription factor 24
chr3_-_33437796 0.18 ENSDART00000075499
si:dkey-283b1.7
si:dkey-283b1.7
chr19_+_27342479 0.18 ENSDART00000184687
ddx39b
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr7_+_50828774 0.17 ENSDART00000182821
per1b
period circadian clock 1b
chr23_-_45705525 0.17 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr4_+_27131725 0.17 ENSDART00000013083
brd1a
bromodomain containing 1a
chr5_+_28161079 0.17 ENSDART00000141109
tacr1a
tachykinin receptor 1a
chr9_+_2002701 0.17 ENSDART00000082329
evx2
even-skipped homeobox 2
chr23_+_42304602 0.17 ENSDART00000166004
cyp2aa11
cytochrome P450, family 2, subfamily AA, polypeptide 11
chr11_-_13126969 0.17 ENSDART00000169052
ENSDART00000190120
elovl1b
ELOVL fatty acid elongase 1b
chr10_+_34394454 0.17 ENSDART00000110121
stard13a
StAR-related lipid transfer (START) domain containing 13a
chr11_-_3343463 0.17 ENSDART00000066177
tuba2
tubulin, alpha 2
chr10_+_35152928 0.16 ENSDART00000063418
nsun5
NOP2/Sun domain family, member 5
chr15_-_32383340 0.16 ENSDART00000185632
c4
complement component 4
chr20_+_18260358 0.16 ENSDART00000187734
ENSDART00000191947
ENSDART00000057039
taf4b
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_-_18508815 0.16 ENSDART00000173539
rgs12a
regulator of G protein signaling 12a
chr1_+_52690448 0.16 ENSDART00000150326
osbp
oxysterol binding protein
chr3_+_37824268 0.16 ENSDART00000137038
asic2
acid-sensing (proton-gated) ion channel 2
chr1_-_45553602 0.16 ENSDART00000143664
grin2bb
glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b
chr2_+_25816843 0.16 ENSDART00000078639
slc2a2
solute carrier family 2 (facilitated glucose transporter), member 2
chr24_+_41915878 0.16 ENSDART00000171523
TMEM200C
transmembrane protein 200C
chr4_+_7391110 0.16 ENSDART00000160708
ENSDART00000187823
tnni4a
troponin I4a
chr21_+_30043054 0.16 ENSDART00000065448
fabp6
fatty acid binding protein 6, ileal (gastrotropin)
chr20_-_5052786 0.15 ENSDART00000138818
ENSDART00000181655
ENSDART00000164274
arid1b
AT rich interactive domain 1B (SWI1-like)
chr24_-_31843173 0.15 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr21_-_38031038 0.15 ENSDART00000179483
ENSDART00000076238
rbm41
RNA binding motif protein 41
chr16_-_14353567 0.15 ENSDART00000139859
itga10
integrin, alpha 10
chr8_-_53680653 0.15 ENSDART00000164739
wnt5a
wingless-type MMTV integration site family, member 5a
chr16_-_41990421 0.15 ENSDART00000055921
pycard
PYD and CARD domain containing
chr16_-_42013858 0.15 ENSDART00000045403
etv2
ets variant 2
chr9_-_21904695 0.15 ENSDART00000134768
lmo7a
LIM domain 7a
chr20_+_33175343 0.14 ENSDART00000131785
ddx1
DEAD (Asp-Glu-Ala-Asp) box helicase 1
chr1_-_21723329 0.14 ENSDART00000137138
si:ch211-134c9.2
si:ch211-134c9.2
chr5_-_33298352 0.14 ENSDART00000015076
zgc:103692
zgc:103692
chr6_-_39765546 0.14 ENSDART00000185767
pfkmb
phosphofructokinase, muscle b
chr6_-_7438584 0.14 ENSDART00000053776
fkbp11
FK506 binding protein 11
chr7_-_41915312 0.14 ENSDART00000159869
dnaja2
DnaJ (Hsp40) homolog, subfamily A, member 2
chr11_+_39672874 0.14 ENSDART00000046663
ENSDART00000157659
camta1b
calmodulin binding transcription activator 1b
chr4_+_646154 0.14 ENSDART00000171138
xpot
exportin, tRNA (nuclear export receptor for tRNAs)
chr8_+_1187928 0.14 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr3_-_9488350 0.13 ENSDART00000186707
FO904885.2

chr20_+_710052 0.13 ENSDART00000166656
senp6a
SUMO1/sentrin specific peptidase 6a
chr7_+_35238234 0.13 ENSDART00000178732
tppp3
tubulin polymerization-promoting protein family member 3
chr25_-_37319117 0.13 ENSDART00000044499
igl4v9
immunoglobulin light 4 variable 9
chr24_+_28525507 0.13 ENSDART00000191121
arhgap29a
Rho GTPase activating protein 29a
chr20_+_33175190 0.13 ENSDART00000023963
ddx1
DEAD (Asp-Glu-Ala-Asp) box helicase 1
chr1_-_37383741 0.13 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr3_+_23743139 0.13 ENSDART00000187409
hoxb3a
homeobox B3a
chr2_-_59145027 0.13 ENSDART00000128320
FO834803.1

chr20_-_45807982 0.12 ENSDART00000074546
fermt1
fermitin family member 1
chr8_+_2487250 0.12 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
chr13_+_13681681 0.12 ENSDART00000057825
cfd
complement factor D (adipsin)
chr8_+_27743550 0.12 ENSDART00000046004
wnt2bb
wingless-type MMTV integration site family, member 2Bb
chr7_+_21887787 0.12 ENSDART00000162252
pop7
POP7 homolog, ribonuclease P/MRP subunit
chr16_-_11778933 0.12 ENSDART00000184916
pafah1b3
platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit
chr21_+_5209716 0.12 ENSDART00000102539
ENSDART00000053148
ENSDART00000102536
st8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr11_-_13126505 0.12 ENSDART00000158377
elovl1b
ELOVL fatty acid elongase 1b
chr1_+_33383971 0.12 ENSDART00000150043
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr25_-_6432463 0.12 ENSDART00000110389
ptpn9a
protein tyrosine phosphatase, non-receptor type 9, a
chr14_+_36738069 0.12 ENSDART00000105590
tdo2a
tryptophan 2,3-dioxygenase a
chr2_-_1188707 0.11 ENSDART00000066378
CABZ01084564.1

chr25_-_3217115 0.11 ENSDART00000032390
gtf2h1
general transcription factor IIH, polypeptide 1
chr11_-_41130239 0.11 ENSDART00000173268
dnajc11b
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr19_+_37620342 0.11 ENSDART00000158960
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr18_-_28938912 0.11 ENSDART00000136201
si:ch211-174j14.2
si:ch211-174j14.2
chr13_-_33822550 0.11 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr5_+_69686368 0.11 ENSDART00000158237
znf1005
zinc finger protein 1005
chr18_+_8346920 0.11 ENSDART00000083421
cpt1b
carnitine palmitoyltransferase 1B (muscle)
chr3_+_23742868 0.11 ENSDART00000153512
hoxb3a
homeobox B3a
chr12_-_32426685 0.11 ENSDART00000105574
enpp7.2
ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 2
chr8_+_30456161 0.11 ENSDART00000085894
pgm5
phosphoglucomutase 5
chr22_+_33362552 0.11 ENSDART00000101580
nicn1
nicolin 1
chr20_+_34845672 0.10 ENSDART00000128895
emilin1a
elastin microfibril interfacer 1a
chr1_-_37383539 0.10 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr9_+_10014817 0.10 ENSDART00000132065
nxph2a
neurexophilin 2a
chr7_-_8374950 0.10 ENSDART00000057101
aep1
aerolysin-like protein

Network of associatons between targets according to the STRING database.

First level regulatory network of mecom

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.1 0.4 GO:0042941 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.1 0.8 GO:0021885 forebrain cell migration(GO:0021885)
0.1 0.4 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.1 0.2 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.4 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.4 GO:0055016 hypochord development(GO:0055016)
0.1 0.3 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.5 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.5 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.5 GO:0070293 renal absorption(GO:0070293)
0.1 0.5 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.4 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.2 GO:0071312 response to cocaine(GO:0042220) cellular response to alkaloid(GO:0071312) cellular response to cocaine(GO:0071314)
0.1 0.3 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.0 1.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0021767 mammillary body development(GO:0021767)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0015677 copper ion import(GO:0015677)
0.0 0.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.2 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 0.1 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.7 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.0 0.3 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.4 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.2 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.4 GO:0060324 face development(GO:0060324)
0.0 0.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.3 GO:0051351 positive regulation of ligase activity(GO:0051351)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595) Spemann organizer formation(GO:0060061)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.5 GO:0007631 feeding behavior(GO:0007631)
0.0 0.2 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529)
0.0 0.0 GO:0060907 macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0061621 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.0 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.5 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0001757 somite specification(GO:0001757)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 1.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.8 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic cytoskeleton(GO:0099569)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.5 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.2 GO:0016496 substance P receptor activity(GO:0016496)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.3 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 1.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.3 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.0 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.0 GO:0031704 apelin receptor binding(GO:0031704)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.7 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation