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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mecp2

Z-value: 1.21

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Transcription factors associated with mecp2

Gene Symbol Gene ID Gene Info
mecp2
ENSDARG00000014218 methyl CpG binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecp2dr11_v1_chr8_-_7637626_76376400.184.8e-01Click!

Activity profile of mecp2 motif

Sorted Z-values of mecp2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_68789 3.53 ENSDART00000058569
cldn1
claudin 1
chr1_-_55248496 2.90 ENSDART00000098615
nanos3
nanos homolog 3
chr2_-_38287987 2.82 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
si:ch211-14a17.6
chr4_-_77561679 2.72 ENSDART00000180809
AL935186.9

chr4_-_12930086 2.62 ENSDART00000013604
lemd3
LEM domain containing 3
chr18_+_18000695 2.59 ENSDART00000146898
si:ch211-212o1.2
si:ch211-212o1.2
chr19_-_27830818 2.54 ENSDART00000131767
papd7
PAP associated domain containing 7
chr4_-_77557279 2.54 ENSDART00000180113
AL935186.10

chr12_-_13730501 2.51 ENSDART00000152370
foxh1
forkhead box H1
chr19_+_14454306 2.46 ENSDART00000161965
zdhhc18b
zinc finger, DHHC-type containing 18b
chr20_+_34502606 2.22 ENSDART00000139739
gorab
golgin, rab6-interacting
chr8_+_48965767 2.13 ENSDART00000008058
aak1a
AP2 associated kinase 1a
chr22_+_105376 2.00 ENSDART00000059140
slc25a20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr8_+_48966165 2.00 ENSDART00000165425
aak1a
AP2 associated kinase 1a
chr15_+_38299563 1.96 ENSDART00000099375
si:dkey-24p1.6
si:dkey-24p1.6
chr21_-_22357545 1.94 ENSDART00000134320
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr15_-_47895200 1.93 ENSDART00000027060
DMWD
zmp:0000000529
chr7_-_51773166 1.93 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr15_+_24737599 1.92 ENSDART00000078024
crk
v-crk avian sarcoma virus CT10 oncogene homolog
chr19_-_31576321 1.90 ENSDART00000103612
tdp2b
tyrosyl-DNA phosphodiesterase 2b
chr13_-_36566260 1.87 ENSDART00000030133
synj2bp
synaptojanin 2 binding protein
chr17_+_24318753 1.86 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr20_-_30035326 1.85 ENSDART00000141068
sox11b
SRY (sex determining region Y)-box 11b
chr9_-_32343673 1.82 ENSDART00000078499
rftn2
raftlin family member 2
chr20_+_32523576 1.82 ENSDART00000147319
scml4
Scm polycomb group protein like 4
chr5_-_12587053 1.80 ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr23_+_20431388 1.72 ENSDART00000132920
ENSDART00000102963
ENSDART00000109899
ENSDART00000140219
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr12_+_24060894 1.69 ENSDART00000021298
asb3
ankyrin repeat and SOCS box containing 3
chr5_-_30382925 1.62 ENSDART00000125381
gig2o
grass carp reovirus (GCRV)-induced gene 2o
chr1_-_54972170 1.62 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr23_-_18568522 1.61 ENSDART00000004655
sephs2
selenophosphate synthetase 2
chr2_-_47620806 1.61 ENSDART00000038228
ap1s3b
adaptor-related protein complex 1, sigma 3 subunit, b
chr19_-_47587719 1.60 ENSDART00000111108
CABZ01071972.1

chr5_+_15992655 1.60 ENSDART00000182148
znrf3
zinc and ring finger 3
chr4_+_3438510 1.57 ENSDART00000155320
atxn7l1
ataxin 7-like 1
chr16_-_43317927 1.53 ENSDART00000164472
washc5
WASH complex subunit 5
chr5_+_872299 1.52 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr25_+_753364 1.50 ENSDART00000183804
TWF1 (1 of many)
twinfilin actin binding protein 1
chr5_+_69950882 1.49 ENSDART00000097359
dnajc25
DnaJ (Hsp40) homolog, subfamily C , member 25
chr20_-_23253630 1.48 ENSDART00000103365
ociad1
OCIA domain containing 1
chr7_-_24112484 1.47 ENSDART00000111923
ajuba
ajuba LIM protein
chr6_+_33931740 1.47 ENSDART00000130492
ENSDART00000151213
orc1
origin recognition complex, subunit 1
chr19_-_32914227 1.47 ENSDART00000186115
ENSDART00000124246
mtdha
metadherin a
chr10_-_6588793 1.46 ENSDART00000163788
chd1
chromodomain helicase DNA binding protein 1
chr16_-_42066523 1.45 ENSDART00000180538
ENSDART00000058620
zp3d.1
zona pellucida glycoprotein 3d tandem duplicate 1
chr23_+_553396 1.45 ENSDART00000034707
lsm14b
LSM family member 14B
chr11_+_2687395 1.44 ENSDART00000082510
b3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr7_+_32693890 1.44 ENSDART00000121972
slc39a13
solute carrier family 39 (zinc transporter), member 13
chr21_-_22357985 1.44 ENSDART00000101751
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr10_+_43037064 1.43 ENSDART00000160159
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr3_-_27880229 1.41 ENSDART00000151404
abat
4-aminobutyrate aminotransferase
chr17_-_27235797 1.40 ENSDART00000130080
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr21_+_13233377 1.40 ENSDART00000142569
specc1lb
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr7_-_41881177 1.38 ENSDART00000174258
ENSDART00000018972
zgc:92818
zgc:92818
chr5_-_9824908 1.37 ENSDART00000169698
zgc:158343
zgc:158343
chr23_+_20431140 1.35 ENSDART00000193950
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr1_-_23294753 1.34 ENSDART00000013263
ugdh
UDP-glucose 6-dehydrogenase
chr5_-_9216758 1.34 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr21_-_44731865 1.32 ENSDART00000013814
ammecr1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 homolog (human)
chr5_+_58455488 1.32 ENSDART00000038602
ENSDART00000127958
slc37a2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr23_-_44819100 1.30 ENSDART00000076373
st8sia7.1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 7.1
chr6_-_59357256 1.30 ENSDART00000074534
fam210b
family with sequence similarity 210, member B
chr15_-_34871968 1.28 ENSDART00000191980
mgat1a
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr12_-_13966184 1.28 ENSDART00000066368
klhl11
kelch-like family member 11
chr14_+_25505468 1.28 ENSDART00000079016
thoc3
THO complex 3
chr15_+_46853252 1.27 ENSDART00000186040
zgc:153039
zgc:153039
chr10_-_36633882 1.27 ENSDART00000077161
ENSDART00000137688
rsf1b.1
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr16_+_33953644 1.24 ENSDART00000164447
ENSDART00000159969
arid1aa
AT rich interactive domain 1Aa (SWI-like)
chr3_+_35005062 1.23 ENSDART00000181163
prkcbb
protein kinase C, beta b
chr1_-_54971968 1.23 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr17_+_52300018 1.22 ENSDART00000190302
esrrb
estrogen-related receptor beta
chr15_+_40188076 1.22 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr13_+_9559461 1.22 ENSDART00000047740
wdr32
WD repeat domain 32
chr14_-_33858214 1.21 ENSDART00000112268
ocrl
oculocerebrorenal syndrome of Lowe
chr4_-_12102025 1.19 ENSDART00000048391
ENSDART00000023894
braf
B-Raf proto-oncogene, serine/threonine kinase
chr11_-_45171139 1.19 ENSDART00000167036
ENSDART00000161712
ENSDART00000158156
syngr2b
synaptogyrin 2b
chr17_-_23709347 1.18 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr24_+_35387517 1.17 ENSDART00000058571
snai2
snail family zinc finger 2
chr15_+_45595385 1.17 ENSDART00000161937
ENSDART00000170214
ENSDART00000157450
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr14_+_46118834 1.17 ENSDART00000124417
ENSDART00000017785
naa15a
N(alpha)-acetyltransferase 15, NatA auxiliary subunit a
chr12_-_33789006 1.17 ENSDART00000034550
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr6_+_41554794 1.16 ENSDART00000165424
srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr20_-_48898560 1.16 ENSDART00000163071
xrn2
5'-3' exoribonuclease 2
chr9_-_32158288 1.15 ENSDART00000037182
ankrd44
ankyrin repeat domain 44
chr19_+_32979331 1.14 ENSDART00000078066
spire1a
spire-type actin nucleation factor 1a
chr4_-_73545626 1.11 ENSDART00000174295
si:ch73-266f23.1
si:ch73-266f23.1
chr14_-_22108718 1.11 ENSDART00000054410
med19a
mediator complex subunit 19a
chr15_-_25367309 1.09 ENSDART00000047471
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr16_+_22864722 1.09 ENSDART00000137783
flad1
flavin adenine dinucleotide synthetase 1
chr12_-_33789218 1.08 ENSDART00000193258
llgl2
lethal giant larvae homolog 2 (Drosophila)
chr19_+_41479990 1.07 ENSDART00000087187
ago2
argonaute RISC catalytic component 2
chr25_-_30357027 1.07 ENSDART00000171137
pdia3
protein disulfide isomerase family A, member 3
chr23_-_32156278 1.07 ENSDART00000157479
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr1_+_40613297 1.04 ENSDART00000040798
ENSDART00000168067
ENSDART00000130490
naa15b
N(alpha)-acetyltransferase 15, NatA auxiliary subunit b
chr20_-_48898371 1.04 ENSDART00000170617
xrn2
5'-3' exoribonuclease 2
chr8_-_11131695 1.04 ENSDART00000055742
nras
NRAS proto-oncogene, GTPase
chr25_+_186583 1.04 ENSDART00000161504
pclaf
PCNA clamp associated factor
chr7_-_25133783 1.03 ENSDART00000173781
ENSDART00000121943
ENSDART00000077219
badb
BCL2 associated agonist of cell death b
chr3_+_17653784 1.03 ENSDART00000159984
ENSDART00000157682
ENSDART00000187937
kat2a
K(lysine) acetyltransferase 2A
chr2_-_57264262 1.03 ENSDART00000183815
ENSDART00000149829
ENSDART00000088508
ENSDART00000149508
mbd3a
methyl-CpG binding domain protein 3a
chr15_+_43398317 1.02 ENSDART00000182528
ENSDART00000172154
ENSDART00000187688
actn4
actinin, alpha 4
chr2_+_25658112 1.02 ENSDART00000051234
tnika
TRAF2 and NCK interacting kinase a
chr2_-_37401600 1.02 ENSDART00000015723
prkci
protein kinase C, iota
chr19_-_11846958 1.02 ENSDART00000148516
ctdp1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr7_+_53254234 1.01 ENSDART00000169830
trip4
thyroid hormone receptor interactor 4
chr11_+_42422371 1.01 ENSDART00000163780
dennd6aa
DENN/MADD domain containing 6Aa
chr3_-_10582384 1.01 ENSDART00000048095
ENSDART00000155152
elac2
elaC ribonuclease Z 2
chr1_+_52632856 1.00 ENSDART00000011725
slc44a1a
solute carrier family 44 (choline transporter), member 1a
chr21_-_2042037 0.99 ENSDART00000171131
ENSDART00000160144
add1
adducin 1 (alpha)
chr7_-_30926030 0.98 ENSDART00000075421
sord
sorbitol dehydrogenase
chr8_+_50190742 0.97 ENSDART00000099863
slc25a37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr3_+_11926030 0.97 ENSDART00000081367
dnaja3a
DnaJ (Hsp40) homolog, subfamily A, member 3A
chr21_-_226071 0.97 ENSDART00000160667
nup54
nucleoporin 54
chr17_-_20202725 0.96 ENSDART00000133650
ecd
ecdysoneless homolog (Drosophila)
chr11_-_25853212 0.96 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr1_+_15258641 0.96 ENSDART00000033018
pi4k2b
phosphatidylinositol 4-kinase type 2 beta
chr25_+_4581214 0.95 ENSDART00000185552
CABZ01068600.1

chr3_-_25054002 0.95 ENSDART00000086768
ep300b
E1A binding protein p300 b
chr18_+_50961953 0.93 ENSDART00000158768
ppfia1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
chr1_-_23370395 0.92 ENSDART00000143014
ENSDART00000126785
ENSDART00000159138
pds5a
PDS5 cohesin associated factor A
chr15_-_47479119 0.92 ENSDART00000164957
inppl1a
inositol polyphosphate phosphatase-like 1a
chr10_+_10972795 0.91 ENSDART00000127331
cdc37l1
cell division cycle 37-like 1
chr11_-_36230146 0.91 ENSDART00000135888
ENSDART00000189782
rrp9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr10_+_3428194 0.90 ENSDART00000081599
ptpn11a
protein tyrosine phosphatase, non-receptor type 11, a
chr8_-_4574328 0.89 ENSDART00000090731
dhx37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr21_-_30030644 0.89 ENSDART00000190810
CU855895.2

chr13_-_36525982 0.88 ENSDART00000114744
pacs2
phosphofurin acidic cluster sorting protein 2
chr6_+_40952031 0.86 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr11_+_2649664 0.86 ENSDART00000166357
si:ch211-160o17.4
si:ch211-160o17.4
chr19_-_7441686 0.84 ENSDART00000168194
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr12_-_18961289 0.83 ENSDART00000168405
ep300a
E1A binding protein p300 a
chr7_-_33829824 0.83 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr5_-_22573624 0.83 ENSDART00000131889
ENSDART00000080886
ENSDART00000147513
ENSDART00000080882
aifm1
apoptosis-inducing factor, mitochondrion-associated 1
chr15_+_46853505 0.82 ENSDART00000159844
zgc:153039
zgc:153039
chr13_-_51922290 0.82 ENSDART00000168648
srfb
serum response factor b
chr6_+_6802142 0.82 ENSDART00000065566
dtd1
D-tyrosyl-tRNA deacylase 1
chr22_-_34609528 0.81 ENSDART00000190781
ENSDART00000171712
terf2ip
telomeric repeat binding factor 2, interacting protein
chr7_+_41887429 0.81 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr13_-_36911118 0.80 ENSDART00000048739
trim9
tripartite motif containing 9
chr11_+_2649891 0.80 ENSDART00000093052
si:ch211-160o17.4
si:ch211-160o17.4
chr8_+_22327251 0.80 ENSDART00000075129
lrrc47
leucine rich repeat containing 47
chr24_+_25210015 0.80 ENSDART00000081043
cip2a
cell proliferation regulating inhibitor of protein phosphatase 2A
chr1_+_12335816 0.80 ENSDART00000067086
nansa
N-acetylneuraminic acid synthase a
chr12_+_33484458 0.79 ENSDART00000000069
slc9a3r1a
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1a
chr14_-_6402769 0.79 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr2_+_25657958 0.79 ENSDART00000161407
tnika
TRAF2 and NCK interacting kinase a
chr12_+_36428052 0.78 ENSDART00000131300
unk
unkempt family zinc finger
chr23_+_44614056 0.77 ENSDART00000188379
eno3
enolase 3, (beta, muscle)
chr9_-_135774 0.76 ENSDART00000160435
FQ377903.1

chr19_+_13994563 0.76 ENSDART00000164696
tmem222b
transmembrane protein 222b
chr20_-_52939501 0.76 ENSDART00000166508
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr19_-_3726768 0.76 ENSDART00000161738
smim13
small integral membrane protein 13
chr11_-_21363834 0.75 ENSDART00000080051
RASSF5
si:dkey-85p17.3
chr23_+_30859086 0.74 ENSDART00000053661
zgc:198371
zgc:198371
chr21_-_14692119 0.74 ENSDART00000123047
ehmt1b
euchromatic histone-lysine N-methyltransferase 1b
chr3_+_48842918 0.73 ENSDART00000159420
hs3st3b1a
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a
chr5_+_4016271 0.72 ENSDART00000113627
ENSDART00000105832
ENSDART00000121415
ggnbp2
gametogenetin binding protein 2
chr12_-_3705862 0.72 ENSDART00000193864
ENSDART00000185857
CABZ01069040.1

chr16_+_22864313 0.71 ENSDART00000164757
flad1
flavin adenine dinucleotide synthetase 1
chr2_-_9744081 0.70 ENSDART00000097732
dvl3a
dishevelled segment polarity protein 3a
chr8_+_14915332 0.70 ENSDART00000164385
abl2
c-abl oncogene 2, non-receptor tyrosine kinase
chr17_+_26803470 0.70 ENSDART00000023470
pgrmc2
progesterone receptor membrane component 2
chr24_+_23840821 0.69 ENSDART00000128595
ENSDART00000127188
pola1
polymerase (DNA directed), alpha 1
chr7_-_30925798 0.69 ENSDART00000149303
sord
sorbitol dehydrogenase
chr5_-_41103583 0.69 ENSDART00000051070
ENSDART00000074781
golph3
golgi phosphoprotein 3
chr20_+_30702531 0.68 ENSDART00000062525
acbd3
acyl-Coenzyme A binding domain containing 3
chr6_+_68220 0.68 ENSDART00000082955
sowahcb
sosondowah ankyrin repeat domain family Cb
chr6_-_10728921 0.67 ENSDART00000151484
sp3b
Sp3b transcription factor
chr3_-_52899394 0.66 ENSDART00000128223
CHCHD5
coiled-coil-helix-coiled-coil-helix domain containing 5
chr4_+_13931578 0.66 ENSDART00000142466
pphln1
periphilin 1
chr1_-_23308225 0.65 ENSDART00000137567
ENSDART00000008201
smim14
small integral membrane protein 14
chr8_-_21071476 0.65 ENSDART00000184184
ENSDART00000100288
zgc:112962
zgc:112962
chr12_-_17492852 0.65 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
minpp1b
multiple inositol-polyphosphate phosphatase 1b
chr5_+_50913357 0.65 ENSDART00000092938
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr9_-_12595003 0.64 ENSDART00000184900
tra2b
transformer 2 beta homolog
chr4_-_13931508 0.63 ENSDART00000067174
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr12_-_27588299 0.63 ENSDART00000178023
ENSDART00000066282
dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr1_-_53407448 0.63 ENSDART00000160033
ENSDART00000172322
elmod2
ELMO/CED-12 domain containing 2
chr20_+_9474841 0.63 ENSDART00000053847
rad51b
RAD51 paralog B
chr19_-_7441948 0.62 ENSDART00000003544
gabpb2a
GA binding protein transcription factor, beta subunit 2a
chr16_-_52966811 0.62 ENSDART00000153758
ENSDART00000009256
brd9
bromodomain containing 9
chr10_+_8554929 0.62 ENSDART00000190849
tbc1d10ab
TBC1 domain family, member 10Ab
chr21_-_2814709 0.61 ENSDART00000097664
SEMA4D
semaphorin 4D
chr6_-_33931696 0.61 ENSDART00000057290
prpf38a
pre-mRNA processing factor 38A
chr5_+_50913034 0.61 ENSDART00000149787
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr17_-_33414781 0.60 ENSDART00000142203
ENSDART00000034638
ccdc28a
coiled-coil domain containing 28A
chr21_-_45685063 0.60 ENSDART00000162422
sar1b
secretion associated, Ras related GTPase 1B
chr17_+_33415319 0.60 ENSDART00000140805
ENSDART00000025501
ENSDART00000146447
snap23.1
synaptosomal-associated protein 23.1
chr19_-_47782916 0.60 ENSDART00000063337
cdca8
cell division cycle associated 8
chr8_-_4327473 0.60 ENSDART00000134378
cux2b
cut-like homeobox 2b
chr21_+_11367253 0.59 ENSDART00000091835
gtf3c5
general transcription factor IIIC, polypeptide 5
chr4_-_13931293 0.59 ENSDART00000067172
zcrb1
zinc finger CCHC-type and RNA binding motif 1
chr22_-_3182965 0.59 ENSDART00000158009
lonp1
lon peptidase 1, mitochondrial
chr1_+_25650917 0.59 ENSDART00000054235
plrg1
pleiotropic regulator 1
chr17_+_43926523 0.58 ENSDART00000121550
ENSDART00000041447
ktn1
kinectin 1
chr5_-_24154437 0.58 ENSDART00000080609
mrps31
mitochondrial ribosomal protein S31
chr11_+_41459408 0.58 ENSDART00000182285
park7
parkinson protein 7
chr23_+_10426219 0.58 ENSDART00000139100
eif4ba
eukaryotic translation initiation factor 4Ba
chr11_-_38510469 0.57 ENSDART00000162305
si:ch211-117k10.3
si:ch211-117k10.3
chr22_-_4398069 0.56 ENSDART00000181893
kdm4b
lysine (K)-specific demethylase 4B

Network of associatons between targets according to the STRING database.

First level regulatory network of mecp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.7 2.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.6 1.8 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.6 1.7 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.5 1.9 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.5 1.4 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.5 2.3 GO:0010719 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.4 1.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.6 GO:0032801 receptor catabolic process(GO:0032801)
0.4 1.2 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.3 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 1.0 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.3 1.0 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.3 2.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3 1.2 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.3 1.4 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.3 0.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 1.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.3 1.0 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.3 4.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 4.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 1.2 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.2 1.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 0.6 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 1.7 GO:0019405 alditol catabolic process(GO:0019405)
0.2 1.0 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 0.6 GO:2000378 methylglyoxal metabolic process(GO:0009438) negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.2 1.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 2.6 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.7 GO:0006272 leading strand elongation(GO:0006272)
0.2 1.9 GO:0046548 retinal rod cell development(GO:0046548)
0.2 0.5 GO:0061355 Wnt protein secretion(GO:0061355)
0.2 0.5 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.6 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.1 1.0 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.1 0.6 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 1.1 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.8 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.9 GO:1902623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1 2.5 GO:0007032 endosome organization(GO:0007032)
0.1 0.9 GO:0098971 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.6 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.1 1.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 0.7 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.7 GO:0030728 ovulation(GO:0030728)
0.1 1.7 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 1.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.8 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.4 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 1.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.0 GO:1903010 regulation of bone development(GO:1903010)
0.1 0.8 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 2.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 2.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 0.5 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.6 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.8 GO:0070475 rRNA base methylation(GO:0070475)
0.1 3.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.0 GO:0061055 myotome development(GO:0061055)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.1 3.5 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.1 1.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.5 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.4 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 3.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.1 1.3 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.3 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 2.7 GO:0043113 receptor clustering(GO:0043113)
0.1 0.5 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 1.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.6 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 1.0 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 1.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 4.8 GO:0006457 protein folding(GO:0006457)
0.0 1.4 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 2.3 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.3 GO:0061056 sclerotome development(GO:0061056)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.2 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.0 0.2 GO:0008105 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 2.1 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.0 1.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.5 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.5 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.6 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.0 GO:0006497 protein lipidation(GO:0006497)
0.0 0.8 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 1.7 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 0.5 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 1.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0099633 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.6 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 3.0 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 1.0 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.1 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.1 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.9 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.7 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0031415 NatA complex(GO:0031415)
0.4 1.3 GO:0031213 RSF complex(GO:0031213)
0.3 1.5 GO:0071203 WASH complex(GO:0071203)
0.2 1.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 1.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.2 GO:0035060 brahma complex(GO:0035060)
0.2 1.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.9 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 2.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.6 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.5 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.0 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 4.0 GO:0016605 PML body(GO:0016605)
0.1 3.1 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 3.1 GO:0043186 P granule(GO:0043186)
0.1 1.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 0.6 GO:0000974 Prp19 complex(GO:0000974)
0.1 0.5 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.4 GO:0005921 gap junction(GO:0005921)
0.1 0.8 GO:0070187 telosome(GO:0070187)
0.1 0.5 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 2.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.1 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.0 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 2.2 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0090576 transcription factor TFIIIB complex(GO:0000126) RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 3.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 3.5 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.9 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 1.6 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.7 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 1.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 2.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.6 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 5.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.5 GO:0005794 Golgi apparatus(GO:0005794)
0.0 3.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.0 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.6 1.8 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.6 2.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.5 1.4 GO:0019777 Atg12 transferase activity(GO:0019777)
0.4 1.3 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 1.2 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 0.8 GO:1990715 mRNA CDS binding(GO:1990715)
0.3 4.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.3 1.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.3 1.3 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.3 1.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.3 2.9 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.3 1.9 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 0.8 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.3 1.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.3 0.8 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.3 0.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.3 4.3 GO:0032190 acrosin binding(GO:0032190)
0.2 0.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 0.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 1.2 GO:0035173 histone kinase activity(GO:0035173)
0.2 2.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.2 0.7 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.2 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.4 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 1.0 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.9 GO:0045159 myosin II binding(GO:0045159)
0.1 1.0 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.1 1.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.3 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 2.3 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 1.2 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1 2.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.6 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 1.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.7 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 3.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.2 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.6 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.2 GO:0030882 lipid antigen binding(GO:0030882)
0.0 0.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.4 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 1.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087)
0.0 3.1 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.9 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.7 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030) neurotrophin binding(GO:0043121)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 4.9 PID MYC PATHWAY C-MYC pathway
0.1 3.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.5 4.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 2.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 2.7 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 0.7 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 2.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 2.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 1.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 1.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)