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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mef2b

Z-value: 0.13

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Transcription factors associated with mef2b

Gene Symbol Gene ID Gene Info
ENSDARG00000093170 myocyte enhancer factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2bdr11_v1_chr22_+_18187857_18187857-0.503.5e-02Click!

Activity profile of mef2b motif

Sorted Z-values of mef2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_17200120 0.24 ENSDART00000147739
glyceraldehyde-3-phosphate dehydrogenase
chr21_+_25777425 0.22 ENSDART00000021620
claudin d
chr23_+_44614056 0.21 ENSDART00000188379
enolase 3, (beta, muscle)
chr7_-_48263516 0.16 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr16_+_35401543 0.15 ENSDART00000171608
RAB42, member RAS oncogene family
chr14_+_14806851 0.14 ENSDART00000169235
FH2 domain containing 2
chr5_-_31926906 0.11 ENSDART00000187340
slingshot protein phosphatase 1b
chr22_-_4769140 0.11 ENSDART00000165235
calreticulin 3a
chr19_+_31585341 0.10 ENSDART00000052185
geminin, DNA replication inhibitor
chr19_+_31585917 0.09 ENSDART00000132182
geminin, DNA replication inhibitor
chr9_-_41153896 0.08 ENSDART00000059667
WD repeat domain 75
chr13_+_1944451 0.08 ENSDART00000125914
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr10_-_8032885 0.08 ENSDART00000188619
ATPase H+ transporting V0 subunit a2a
chr3_-_61205711 0.08 ENSDART00000055062
parvalbumin 1
chr24_+_8736497 0.08 ENSDART00000181904
transmembrane protein 14Ca
chr14_+_14806692 0.08 ENSDART00000193050
FH2 domain containing 2
chr3_-_7897563 0.08 ENSDART00000185232
ubinuclein 2b
chr14_+_30285613 0.08 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr7_+_32695954 0.07 ENSDART00000184425
solute carrier family 39 (zinc transporter), member 13
chr21_+_12010505 0.07 ENSDART00000123522
aquaporin 7
chr3_-_7897305 0.07 ENSDART00000169757
ubinuclein 2b
chr6_-_42003780 0.06 ENSDART00000032527
caveolin 3
chr7_-_30143092 0.06 ENSDART00000173636
FERM domain containing 5
chr19_-_32518556 0.06 ENSDART00000103410
zinc finger and BTB domain containing 8B
chr4_+_11464255 0.06 ENSDART00000008584
GDP dissociation inhibitor 2
chr14_+_2487672 0.06 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr10_-_2527342 0.05 ENSDART00000184168

chr1_+_19708508 0.05 ENSDART00000054581
ENSDART00000131206
membrane-associated ring finger (C3HC4) 1
chr5_+_36666715 0.05 ENSDART00000097686
zgc:153990
chr9_+_50599362 0.05 ENSDART00000023105
fidgetin
chr10_-_2522588 0.05 ENSDART00000081926

chr20_+_37794633 0.05 ENSDART00000022060
activating transcription factor 3
chr23_+_22658700 0.05 ENSDART00000192248
enolase 1a, (alpha)
chr17_-_50233493 0.05 ENSDART00000172266
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr13_+_11439486 0.05 ENSDART00000138312
zinc finger and BTB domain containing 18
chr6_+_14301214 0.05 ENSDART00000129491
transmembrane protein 182b
chr19_-_7321221 0.05 ENSDART00000092375
oxidation resistance 1b
chr14_-_24332786 0.05 ENSDART00000173164
family with sequence similarity 13, member B
chr10_-_17170086 0.05 ENSDART00000020122
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr4_+_77060861 0.05 ENSDART00000174271
ENSDART00000174393
ENSDART00000150450
si:dkey-240n22.8
chr20_-_7000225 0.04 ENSDART00000100098
adenylate cyclase 1a
chr4_-_4261673 0.04 ENSDART00000150694
CD9 molecule b
chr10_+_29259882 0.04 ENSDART00000180606
synaptotagmin-like 2a
chr24_-_28333029 0.04 ENSDART00000149015
ENSDART00000129174
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr2_-_7131657 0.04 ENSDART00000175565
ENSDART00000092116
exostosin-like glycosyltransferase 2
chr3_-_18189283 0.04 ENSDART00000049240
transducer of ERBB2, 1a
chr13_-_36582341 0.04 ENSDART00000137335
lectin, galactoside binding soluble 3a
chr1_-_45662774 0.04 ENSDART00000042158
serine hydrolase-like
chr10_-_8033468 0.04 ENSDART00000140476
ATPase H+ transporting V0 subunit a2a
chr19_-_8096984 0.04 ENSDART00000146987
si:dkey-266f7.9
chr3_-_32818607 0.04 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr6_-_6248893 0.04 ENSDART00000124662
reticulon 4a
chr21_+_25669934 0.04 ENSDART00000101203
sulfatase modifying factor 2
chr1_-_17569793 0.03 ENSDART00000125125
acyl-CoA synthetase long chain family member 1a
chr6_+_27897313 0.03 ENSDART00000128935
centrosomal protein 63
chr9_-_4018452 0.03 ENSDART00000181059
ubiquitin protein ligase E3 component n-recognin 3
chr10_+_29260096 0.03 ENSDART00000088973
synaptotagmin-like 2a
chr6_+_27896657 0.03 ENSDART00000079419
centrosomal protein 63
chr20_-_26383368 0.03 ENSDART00000024518
ENSDART00000087844
estrogen receptor 1
chr2_-_42704863 0.03 ENSDART00000140159
myosin X
chr5_-_9948497 0.03 ENSDART00000183196
torsin family 4, member Ab
chr18_+_40354998 0.03 ENSDART00000098791
ENSDART00000049171
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr7_+_39679944 0.03 ENSDART00000133420
TBC1 domain family, member 14
chr6_+_51713076 0.03 ENSDART00000146281
RIPOR family member 3
chr25_-_13381854 0.03 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr2_-_4787566 0.03 ENSDART00000160663
ENSDART00000157808
tyrosine kinase, non-receptor, 2b
chr1_-_25936677 0.03 ENSDART00000146488
ENSDART00000136321
myozenin 2b
chr18_+_20034023 0.03 ENSDART00000139441
mortality factor 4 like 1
chr11_-_7139555 0.03 ENSDART00000016472
bone morphogenetic protein 7a
chr6_+_12503849 0.03 ENSDART00000149529
serine/threonine kinase 24b (STE20 homolog, yeast)
chr18_+_49248389 0.03 ENSDART00000059285
ENSDART00000142004
ENSDART00000132751
Yip1 interacting factor homolog B (S. cerevisiae)
chr25_-_29363934 0.03 ENSDART00000166889
neuroplastin a
chr17_-_14671098 0.03 ENSDART00000037371
protein phosphatase 1, regulatory subunit 13Ba
chr4_-_20222182 0.02 ENSDART00000132464
gamma-secretase activating protein
chr7_-_23745984 0.02 ENSDART00000048050
zgc:92429
chr23_-_36670369 0.02 ENSDART00000006881
zinc finger and BTB domain containing 39
chr4_+_13449775 0.02 ENSDART00000172552
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr24_-_7777389 0.02 ENSDART00000138541
RPGR interacting protein 1
chr21_+_19368720 0.02 ENSDART00000187759
ENSDART00000185829
ENSDART00000158471
ENSDART00000168728
betacellulin, epidermal growth factor family member
chr22_-_26852516 0.02 ENSDART00000005829
glycerophosphodiester phosphodiesterase 1
chr8_-_53166975 0.02 ENSDART00000114683
rabenosyn, RAB effector
chr5_-_25236340 0.02 ENSDART00000162774
ATP-binding cassette, sub-family A (ABC1), member 2
chr3_+_31717291 0.02 ENSDART00000058221
ddb1 and cul4 associated factor 7
chr17_-_23545716 0.02 ENSDART00000079534
5-hydroxytryptamine (serotonin) receptor 7a
chr9_+_29985010 0.02 ENSDART00000020743
cms1 ribosomal small subunit homolog (yeast)
chr10_+_37145007 0.02 ENSDART00000131777
CUE domain containing 1a
chr2_+_23352302 0.02 ENSDART00000187760
ring finger protein 2
chr21_+_11684830 0.02 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr4_+_14343706 0.02 ENSDART00000142845
prolactin 2
chr11_-_1948784 0.02 ENSDART00000082475
nuclear receptor subfamily 1, group D, member 4b
chr23_-_38497705 0.02 ENSDART00000109493
teashirt zinc finger homeobox 2
chr5_+_61657702 0.02 ENSDART00000134387
ENSDART00000171248
adaptor-related protein complex 2, beta 1 subunit
chr11_-_26701611 0.02 ENSDART00000083010
acyl-CoA dehydrogenase family, member 9
chr21_+_11685009 0.02 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr18_+_26719787 0.02 ENSDART00000141672
alpha-kinase 3a
chr16_+_29663809 0.02 ENSDART00000191336
tropomodulin 4 (muscle)
chr5_+_61658282 0.02 ENSDART00000188878
adaptor-related protein complex 2, beta 1 subunit
chr5_+_44346691 0.02 ENSDART00000034523
threonyl-tRNA synthetase
chr24_+_9178064 0.02 ENSDART00000142971
discs, large (Drosophila) homolog-associated protein 1b
chr19_+_41169996 0.02 ENSDART00000048438
ankyrin repeat and SOCS box containing 4
chr3_+_1735214 0.02 ENSDART00000185454

chr7_+_50464500 0.02 ENSDART00000191356
serine incorporator 4
chr15_-_36347858 0.01 ENSDART00000155274
ENSDART00000157936
si:dkey-23k10.2
chr7_+_3442834 0.01 ENSDART00000138247
si:ch211-285c6.2
chr3_+_23092762 0.01 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr9_-_23894392 0.01 ENSDART00000133417
ankyrin repeat and SOCS box containing 18
chr7_-_49646251 0.01 ENSDART00000193674
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr21_+_39432248 0.01 ENSDART00000179938
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr24_-_26369185 0.01 ENSDART00000080039
leucine rich repeat containing 31
chr4_-_23908802 0.01 ENSDART00000138873
cugbp, Elav-like family member 2
chr18_+_7264961 0.01 ENSDART00000188461

chr15_+_20543770 0.01 ENSDART00000092357
small G protein signaling modulator 2
chr22_+_9772754 0.01 ENSDART00000130194

chr11_-_11336986 0.01 ENSDART00000016677
zgc:77929
chr7_-_52334840 0.01 ENSDART00000174173

chr21_+_43559123 0.01 ENSDART00000151212
G protein-coupled receptor 185 a
chr20_+_45620076 0.01 ENSDART00000113806
heterogeneous nuclear ribonucleoprotein A0, like
chr25_-_29988352 0.01 ENSDART00000067059
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr14_+_1240419 0.01 ENSDART00000181248
adenosine deaminase domain containing 1 (testis-specific)
chr10_-_17501528 0.01 ENSDART00000144847
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr6_+_52918537 0.01 ENSDART00000174229
odorant receptor, family H, subfamily 137, member 1
chr4_-_13509946 0.01 ENSDART00000134720
interferon, gamma 1-2
chr17_-_15600455 0.01 ENSDART00000110272
ENSDART00000156911
si:ch211-266g18.9
chr24_+_25471196 0.01 ENSDART00000066625
small muscle protein, X-linked
chr4_-_5863906 0.01 ENSDART00000169424
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr16_+_25245857 0.01 ENSDART00000155220
kelch-like family member 38b
chr13_-_36581875 0.01 ENSDART00000113204
lectin, galactoside binding soluble 3a
chr5_+_16580739 0.01 ENSDART00000135140
5-hydroxytryptamine (serotonin) receptor 7c
chr7_+_21859337 0.01 ENSDART00000159626
si:dkey-85k7.7
chr6_-_14139503 0.01 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr14_+_1240235 0.01 ENSDART00000127477
adenosine deaminase domain containing 1 (testis-specific)
chr8_+_44420108 0.01 ENSDART00000075381

chr8_+_4337312 0.01 ENSDART00000182228
myosin, light chain 2b, regulatory, cardiac, slow
chr12_-_26430507 0.01 ENSDART00000153214
synaptopodin 2-like b
chr4_-_72144903 0.01 ENSDART00000186600
solute carrier organic anion transporter family, member 1F1
chr15_-_14755236 0.01 ENSDART00000166880
ENSDART00000160302
prolyl 4-hydroxylase, alpha polypeptide III
chr10_-_41450367 0.01 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr15_-_14552101 0.01 ENSDART00000171169
numb homolog (Drosophila)-like
chr17_-_26867725 0.01 ENSDART00000153590
si:dkey-221l4.10
chr21_-_25669820 0.01 ENSDART00000148236
transmembrane protein 179B
chr2_+_35880600 0.01 ENSDART00000004277
laminin, gamma 1
chr13_-_27767330 0.01 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr11_+_29965822 0.01 ENSDART00000127049
interleukin-1 family member A
chr22_-_9199911 0.01 ENSDART00000138646
si:ch211-213a13.5
chr5_+_67390115 0.01 ENSDART00000193255
early B cell factor 2
chr25_-_21816269 0.01 ENSDART00000152014
zgc:158222
chr5_-_30151815 0.01 ENSDART00000156048
zinc finger and BTB domain containing 44
chr6_-_35472923 0.01 ENSDART00000185907
regulator of G protein signaling 8
chr7_+_20563305 0.01 ENSDART00000169661
si:dkey-19b23.10
chr13_+_42011287 0.01 ENSDART00000131147
cytochrome P450, family 1, subfamily B, polypeptide 1
chr17_-_50234004 0.01 ENSDART00000058706
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr23_-_25050329 0.01 ENSDART00000140216
arginine vasopressin receptor 2a, duplicate a
chr5_-_18911114 0.01 ENSDART00000014434
bri3 binding protein
chr6_+_38896158 0.01 ENSDART00000029930
ENSDART00000131347
solute carrier family 48 (heme transporter), member 1b
chr4_+_76353418 0.01 ENSDART00000171289
si:ch73-158p21.2
chr9_-_48184823 0.01 ENSDART00000180264
kelch-like family member 23
chr23_-_39849155 0.01 ENSDART00000115330
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr24_+_26088143 0.01 ENSDART00000171129

chr11_-_18253111 0.01 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr15_+_31462664 0.01 ENSDART00000174267
ENSDART00000185665
ENSDART00000060087
odorant receptor, family C, subfamily 102, member 1
chr20_+_34455645 0.01 ENSDART00000135789
methyltransferase like 11B
chr2_-_33993533 0.00 ENSDART00000140910
ENSDART00000077304
patched 2
chr25_-_20691609 0.00 ENSDART00000186942
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr17_+_45648836 0.00 ENSDART00000155037
zgc:162184
chr9_-_33107237 0.00 ENSDART00000013918
calsequestrin 2
chr20_-_26001288 0.00 ENSDART00000136518
ENSDART00000063177
calpain 3b
chr24_-_32665283 0.00 ENSDART00000038364
carbonic anhydrase II
chr10_+_8688678 0.00 ENSDART00000147568
si:dkey-27b3.4
chr7_-_27686021 0.00 ENSDART00000079112
ENSDART00000100989
calcitonin/calcitonin-related polypeptide, alpha
chr20_+_15552657 0.00 ENSDART00000063912
Jun proto-oncogene, AP-1 transcription factor subunit
chr12_+_30563550 0.00 ENSDART00000126064
si:ch211-28p3.4
chr15_-_41503392 0.00 ENSDART00000169351
si:dkey-230i18.2
chr1_-_17570013 0.00 ENSDART00000146946
acyl-CoA synthetase long chain family member 1a
chr13_+_9432501 0.00 ENSDART00000058064
zgc:123321
chr5_+_67390645 0.00 ENSDART00000014822
early B cell factor 2
chr7_+_38349667 0.00 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr7_-_31938938 0.00 ENSDART00000132353
brain-derived neurotrophic factor
chr6_-_46403475 0.00 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr20_+_40739964 0.00 ENSDART00000061251
ENSDART00000156669
connexin 28.1
chr16_-_30655980 0.00 ENSDART00000146508
low density lipoprotein receptor class A domain containing 4b
chr12_-_36740781 0.00 ENSDART00000105484
si:ch211-216b21.2
chr3_-_49504023 0.00 ENSDART00000168108
protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a
chr8_-_17980317 0.00 ENSDART00000129148
TNNI3 interacting kinase
chr5_+_51597677 0.00 ENSDART00000048210
ENSDART00000184797
creatine kinase, mitochondrial 2b (sarcomeric)
chr9_+_24065855 0.00 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr1_-_44638058 0.00 ENSDART00000081835
solute carrier family 43 (amino acid system L transporter), member 1b
chr3_+_31093455 0.00 ENSDART00000153074
si:dkey-66i24.9
chr11_-_34478225 0.00 ENSDART00000189604
xyloside xylosyltransferase 1
chr1_-_55210619 0.00 ENSDART00000111671
methylthioribose-1-phosphate isomerase 1
chr19_+_44039849 0.00 ENSDART00000086040
leucine rich repeat containing 14B
chr14_-_32405387 0.00 ENSDART00000184647
fibroblast growth factor 13a

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.2 GO:0051145 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.0 0.1 GO:0019863 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex