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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mef2d

Z-value: 0.82

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Transcription factors associated with mef2d

Gene Symbol Gene ID Gene Info
mef2d
ENSDARG00000040237 myocyte enhancer factor 2d

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2ddr11_v1_chr16_-_29164379_291643790.744.2e-04Click!

Activity profile of mef2d motif

Sorted Z-values of mef2d motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_36948586 2.26 ENSDART00000193606
h3f3c
H3 histone, family 3C
chr3_+_28953274 2.11 ENSDART00000133528
ENSDART00000103602
lgals2a
lectin, galactoside-binding, soluble, 2a
chr22_-_906757 2.05 ENSDART00000193182
FP016205.1

chr10_-_22845485 1.89 ENSDART00000079454
vamp2
vesicle-associated membrane protein 2
chr5_-_38643188 1.89 ENSDART00000144972
si:ch211-271e10.1
si:ch211-271e10.1
chr16_+_34523515 1.74 ENSDART00000041007
stmn1b
stathmin 1b
chr17_-_5769196 1.70 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr10_-_29816467 1.51 ENSDART00000055913
hist2h2l
histone 2, H2, like
chr20_-_22778394 1.49 ENSDART00000152645
fip1l1a
FIP1 like 1a (S. cerevisiae)
chr12_-_36521767 1.46 ENSDART00000110290
unc13d
unc-13 homolog D (C. elegans)
chr15_+_40008370 1.46 ENSDART00000063783
itm2ca
integral membrane protein 2Ca
chr7_-_28148310 1.45 ENSDART00000044208
lmo1
LIM domain only 1
chr8_-_50259448 1.43 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr8_+_44703864 1.36 ENSDART00000016225
star
steroidogenic acute regulatory protein
chr5_-_72125551 1.27 ENSDART00000149412
smyd1a
SET and MYND domain containing 1a
chr2_+_49569017 1.21 ENSDART00000109471
sema4e
semaphorin 4e
chr23_-_23401305 1.18 ENSDART00000078936
her9
hairy-related 9
chr25_-_4482449 1.17 ENSDART00000056278
ENSDART00000149425
slc25a22a
solute carrier family 25 member 22a
chr10_+_29816681 1.17 ENSDART00000100022
h2afx1
H2A histone family member X1
chr4_-_12795030 1.15 ENSDART00000150427
b2m
beta-2-microglobulin
chr20_+_41549200 1.15 ENSDART00000135715
fam184a
family with sequence similarity 184, member A
chr23_-_40766518 1.11 ENSDART00000127420
si:dkeyp-27c8.2
si:dkeyp-27c8.2
chr8_+_22930627 1.10 ENSDART00000187860
sypa
synaptophysin a
chr5_-_63286077 1.10 ENSDART00000131274
tbcelb
tubulin folding cofactor E-like b
chr21_+_40589770 1.10 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pdk3b
pyruvate dehydrogenase kinase, isozyme 3b
chr24_-_4765740 1.08 ENSDART00000121576
cpb1
carboxypeptidase B1 (tissue)
chr4_-_9592402 1.04 ENSDART00000114060
cdnf
cerebral dopamine neurotrophic factor
chr2_+_6181383 1.04 ENSDART00000153307
si:ch73-344o19.1
si:ch73-344o19.1
chr14_+_23520986 1.04 ENSDART00000170473
ENSDART00000175970
si:ch211-221f10.2
si:ch211-221f10.2
chr3_-_52674089 1.03 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
si:dkey-210j14.4
chr5_+_62723233 1.02 ENSDART00000183718
nanos2
nanos homolog 2
chr10_-_3332362 1.01 ENSDART00000007577
ENSDART00000055140
tor4aa
torsin family 4, member Aa
chr10_-_24371312 1.01 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr5_-_19394440 0.99 ENSDART00000163771
foxn4
forkhead box N4
chr25_-_16554757 0.99 ENSDART00000154480
si:ch211-266k8.6
si:ch211-266k8.6
chr13_-_37647209 0.99 ENSDART00000189102
si:dkey-188i13.10
si:dkey-188i13.10
chr17_-_10025234 0.99 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr22_+_16320076 0.96 ENSDART00000164161
osbpl1a
oxysterol binding protein-like 1A
chr4_-_12795436 0.95 ENSDART00000131026
ENSDART00000075127
b2m
beta-2-microglobulin
chr14_+_24215046 0.93 ENSDART00000079215
stc2a
stanniocalcin 2a
chr5_-_10946232 0.92 ENSDART00000163139
ENSDART00000031265
rtn4r
reticulon 4 receptor
chr13_-_28674422 0.89 ENSDART00000122754
ENSDART00000057574
nt5c2a
5'-nucleotidase, cytosolic IIa
chr1_+_7546259 0.88 ENSDART00000015732
mylz3
myosin, light polypeptide 3, skeletal muscle
chr16_-_31919568 0.87 ENSDART00000027364
rbfox1l
RNA binding fox-1 homolog 1, like
chr25_-_7753207 0.86 ENSDART00000126499
phf21ab
PHD finger protein 21Ab
chr23_+_20110086 0.86 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr3_-_31655796 0.85 ENSDART00000181052
CU062431.1

chr14_-_36799280 0.83 ENSDART00000168615
rnf130
ring finger protein 130
chr25_+_32530976 0.82 ENSDART00000156190
ENSDART00000103324
scaper
S-phase cyclin A-associated protein in the ER
chr23_+_20687340 0.81 ENSDART00000143503
usp21
ubiquitin specific peptidase 21
chr9_-_21382190 0.81 ENSDART00000110943
ENSDART00000188129
ENSDART00000193876
ift88
intraflagellar transport 88 homolog
chr21_+_22828500 0.80 ENSDART00000151109
si:rp71-1p14.7
si:rp71-1p14.7
chr15_+_37412883 0.79 ENSDART00000156474
zbtb32
zinc finger and BTB domain containing 32
chr22_+_15898221 0.78 ENSDART00000062587
klf2a
Kruppel-like factor 2a
chr1_-_58592866 0.78 ENSDART00000161039
adgre5b.2
adhesion G protein-coupled receptor E5b, duplicate 2
chr22_+_16497670 0.77 ENSDART00000014330
ier5
immediate early response 5
chr23_+_32011768 0.77 ENSDART00000053509
plagx
pleiomorphic adenoma gene X
chr24_+_17068724 0.77 ENSDART00000191137
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr8_+_17987215 0.77 ENSDART00000113605
lrriq3
leucine-rich repeats and IQ motif containing 3
chr17_+_42842632 0.76 ENSDART00000155547
ENSDART00000126087
qpct
glutaminyl-peptide cyclotransferase
chr23_+_20705849 0.76 ENSDART00000079538
ccdc30
coiled-coil domain containing 30
chr11_+_11201096 0.76 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myom2a
myomesin 2a
chr24_+_17069420 0.76 ENSDART00000014787
pip4k2aa
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr21_-_5799122 0.74 ENSDART00000129351
ENSDART00000151202
ccni
cyclin I
chr9_+_31795343 0.74 ENSDART00000139584
itgbl1
integrin, beta-like 1
chr7_+_14291323 0.73 ENSDART00000053521
rhcga
Rh family, C glycoprotein a
chr9_-_23891102 0.72 ENSDART00000186799
asb18
ankyrin repeat and SOCS box containing 18
chr22_+_38310957 0.72 ENSDART00000040550
traf5
Tnf receptor-associated factor 5
chr6_-_40722480 0.71 ENSDART00000188187
kbtbd12
kelch repeat and BTB (POZ) domain containing 12
chr12_-_17707449 0.71 ENSDART00000142427
ENSDART00000034914
pvalb3
parvalbumin 3
chr3_+_32425202 0.70 ENSDART00000156464
prr12b
proline rich 12b
chr9_-_43142636 0.70 ENSDART00000134349
ENSDART00000181835
ccdc141
coiled-coil domain containing 141
chr12_-_19007834 0.70 ENSDART00000153248
chadlb
chondroadherin-like b
chr22_-_31059670 0.69 ENSDART00000022445
cand2
cullin-associated and neddylation-dissociated 2 (putative)
chr23_+_44497701 0.68 ENSDART00000149903
si:ch73-375g18.1
si:ch73-375g18.1
chr3_+_18398876 0.66 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr8_-_46321889 0.66 ENSDART00000075189
ENSDART00000122801
mtor
mechanistic target of rapamycin kinase
chr19_+_40983221 0.64 ENSDART00000144544
col1a2
collagen, type I, alpha 2
chr25_+_13791627 0.64 ENSDART00000159278
zgc:92873
zgc:92873
chr7_-_40993456 0.64 ENSDART00000031700
en2a
engrailed homeobox 2a
chr3_+_18399315 0.64 ENSDART00000110842
rps2
ribosomal protein S2
chr17_+_32374876 0.63 ENSDART00000183851
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr20_+_46371458 0.63 ENSDART00000152912
adgrg11
adhesion G protein-coupled receptor G11
chr21_+_28445052 0.63 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr17_-_13026634 0.62 ENSDART00000113713
fam177a1
family with sequence similarity 177, member A1
chr1_-_11075403 0.61 ENSDART00000102903
ENSDART00000170290
dmd
dystrophin
chr23_+_23022790 0.61 ENSDART00000189843
samd11
sterile alpha motif domain containing 11
chr8_-_25002182 0.61 ENSDART00000078792
ahcyl1
adenosylhomocysteinase-like 1
chr16_+_16968682 0.60 ENSDART00000111074
si:ch211-120k19.1
si:ch211-120k19.1
chr2_-_43168292 0.58 ENSDART00000132588
crema
cAMP responsive element modulator a
chr10_-_22803740 0.58 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr24_-_24038800 0.58 ENSDART00000080549
lyz
lysozyme
chr9_-_34300707 0.58 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr17_+_7513673 0.58 ENSDART00000156674
klhl10b.1
kelch-like family member 10b, tandem duplicate 1
chr16_-_22713152 0.58 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
si:ch211-105c13.3
chr3_+_18555899 0.58 ENSDART00000163036
ENSDART00000158791
cbx4
chromobox homolog 4 (Pc class homolog, Drosophila)
chr2_+_2737422 0.57 ENSDART00000032459
aqp1a.1
aquaporin 1a (Colton blood group), tandem duplicate 1
chr21_-_22828593 0.56 ENSDART00000150993
angptl5
angiopoietin-like 5
chr16_+_16969060 0.56 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
rpl18
si:ch211-120k19.1
ribosomal protein L18
chr14_-_30704075 0.56 ENSDART00000134098
efemp2a
EGF containing fibulin extracellular matrix protein 2a
chr9_+_17438765 0.56 ENSDART00000138953
rgcc
regulator of cell cycle
chr1_-_411331 0.55 ENSDART00000092524
rasa3
RAS p21 protein activator 3
chr10_+_2981090 0.55 ENSDART00000111830
zfyve16
zinc finger, FYVE domain containing 16
chr5_-_48268049 0.55 ENSDART00000187454
mef2cb
myocyte enhancer factor 2cb
chr20_+_812012 0.55 ENSDART00000179299
ENSDART00000137135
mei4
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr2_-_16562505 0.55 ENSDART00000156406
atp1b3a
ATPase Na+/K+ transporting subunit beta 3a
chr21_+_19070921 0.55 ENSDART00000029874
nkx6.1
NK6 homeobox 1
chr20_+_15552657 0.54 ENSDART00000063912
jun
Jun proto-oncogene, AP-1 transcription factor subunit
chr4_+_11375894 0.54 ENSDART00000190471
ENSDART00000143963
pcloa
piccolo presynaptic cytomatrix protein a
chr20_+_16881883 0.53 ENSDART00000130107
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr25_+_3677650 0.53 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr1_-_53907092 0.53 ENSDART00000007732
capn9
calpain 9
chr19_-_38611814 0.52 ENSDART00000151958
col16a1
collagen, type XVI, alpha 1
chr12_+_6002715 0.51 ENSDART00000114961
si:ch211-131k2.3
si:ch211-131k2.3
chr10_-_4980150 0.51 ENSDART00000093228
mat2al
methionine adenosyltransferase II, alpha-like
chr20_-_36617313 0.50 ENSDART00000172395
ENSDART00000152856
enah
enabled homolog (Drosophila)
chr2_+_29976419 0.50 ENSDART00000056748
en2b
engrailed homeobox 2b
chr8_-_25728628 0.49 ENSDART00000127237
foxp3a
forkhead box P3a
chr4_-_57530817 0.49 ENSDART00000158435
zgc:173702
zgc:173702
chr8_-_26388090 0.49 ENSDART00000147912
si:dkey-20d21.12
si:dkey-20d21.12
chr25_-_3644574 0.49 ENSDART00000188569
si:ch211-272n13.3
si:ch211-272n13.3
chr17_+_15899039 0.48 ENSDART00000154181
syne3
spectrin repeat containing, nuclear envelope family member 3
chr8_+_52637507 0.48 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr14_-_21064199 0.48 ENSDART00000172099
si:dkey-74k8.3
si:dkey-74k8.3
chr14_-_21063977 0.47 ENSDART00000164373
si:dkey-74k8.3
si:dkey-74k8.3
chr16_-_24518027 0.47 ENSDART00000134120
ENSDART00000143761
cadm4
cell adhesion molecule 4
chr10_+_29698467 0.46 ENSDART00000163402
dlg2
discs, large homolog 2 (Drosophila)
chr5_-_22619879 0.46 ENSDART00000051623
zgc:113208
zgc:113208
chr12_+_33894665 0.45 ENSDART00000004769
mfsd13a
major facilitator superfamily domain containing 13A
chr11_-_3860534 0.45 ENSDART00000082425
gata2a
GATA binding protein 2a
chr15_+_47903864 0.45 ENSDART00000063835
otx5
orthodenticle homolog 5
chr9_-_52814204 0.45 ENSDART00000140771
ENSDART00000007401
MAP3K13
si:ch211-45c16.2
chr9_-_12424791 0.45 ENSDART00000135447
ENSDART00000088199
zgc:162707
zgc:162707
chr7_-_7420301 0.44 ENSDART00000102620
six7
SIX homeobox 7
chr11_-_18601955 0.44 ENSDART00000180565
zmynd8
zinc finger, MYND-type containing 8
chr22_-_29204960 0.44 ENSDART00000131386
pvalb7
parvalbumin 7
chr15_-_23645810 0.44 ENSDART00000168845
ckmb
creatine kinase, muscle b
chr23_+_6077503 0.44 ENSDART00000081714
ENSDART00000139834
mybpha
myosin binding protein Ha
chr18_+_30567945 0.43 ENSDART00000078894
irf8
interferon regulatory factor 8
chr12_-_36521947 0.43 ENSDART00000152946
unc13d
unc-13 homolog D (C. elegans)
chr7_+_31879649 0.43 ENSDART00000099789
mybpc3
myosin binding protein C, cardiac
chr1_-_6494384 0.42 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr14_-_30366196 0.42 ENSDART00000007022
pdgfrl
platelet-derived growth factor receptor-like
chr19_-_25464291 0.42 ENSDART00000112915
umad1
UBAP1-MVB12-associated (UMA) domain containing 1
chr7_-_18547420 0.41 ENSDART00000173969
rgs12a
regulator of G protein signaling 12a
chr6_+_29410986 0.41 ENSDART00000065293
usp13
ubiquitin specific peptidase 13
chr18_-_2639351 0.41 ENSDART00000168106
relt
RELT, TNF receptor
chr14_-_24081929 0.41 ENSDART00000158576
msx2a
muscle segment homeobox 2a
chr21_-_22951604 0.41 ENSDART00000083449
ENSDART00000180129
dub
duboraya
chr12_+_16440708 0.40 ENSDART00000113810
ankrd1b
ankyrin repeat domain 1b (cardiac muscle)
chr13_-_37636147 0.40 ENSDART00000144065
si:dkey-188i13.8
si:dkey-188i13.8
chr8_+_17184602 0.40 ENSDART00000050228
ENSDART00000140531
dimt1l
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr19_+_3056450 0.40 ENSDART00000141324
ENSDART00000082353
hsf1
heat shock transcription factor 1
chr24_-_35534273 0.39 ENSDART00000026578
ube2v2
ubiquitin-conjugating enzyme E2 variant 2
chr7_+_38811800 0.39 ENSDART00000052322
zgc:110699
zgc:110699
chr5_+_66132394 0.39 ENSDART00000073892
zgc:114041
zgc:114041
chr15_+_15856178 0.39 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr22_+_10606863 0.38 ENSDART00000147975
rad54l2
RAD54 like 2
chr25_+_31264155 0.38 ENSDART00000012256
tnni2a.3
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr17_-_24439672 0.38 ENSDART00000155020
wdpcp
WD repeat containing planar cell polarity effector
chr16_-_32975951 0.37 ENSDART00000101969
ENSDART00000175149
me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr16_+_29663809 0.37 ENSDART00000191336
tmod4
tropomodulin 4 (muscle)
chr2_-_22492289 0.37 ENSDART00000168022
gtf2b
general transcription factor IIB
chr22_+_29204885 0.37 ENSDART00000133409
ENSDART00000059820
ncf4
neutrophil cytosolic factor 4
chr23_+_23485858 0.36 ENSDART00000114067
agrn
agrin
chr3_-_14103551 0.36 ENSDART00000127604
nfil3-6
nuclear factor, interleukin 3 regulated, member 6
chr11_+_40148181 0.36 ENSDART00000125119
si:dkey-264d12.5
si:dkey-264d12.5
chr2_-_6182098 0.35 ENSDART00000156167
si:ch73-182a11.2
si:ch73-182a11.2
chr25_+_20716176 0.35 ENSDART00000073651
ergic2
ERGIC and golgi 2
chr22_+_10606573 0.35 ENSDART00000192638
rad54l2
RAD54 like 2
chr13_-_11536951 0.35 ENSDART00000018155
adss
adenylosuccinate synthase
chr21_+_27448856 0.35 ENSDART00000100784
cfbl
complement factor b-like
chr18_+_17959681 0.34 ENSDART00000142700
znf423
zinc finger protein 423
chr25_+_29160102 0.34 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr16_+_5259886 0.34 ENSDART00000186668
plecb
plectin b
chr11_-_39202915 0.34 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr3_-_13946446 0.33 ENSDART00000171249
gcdhb
glutaryl-CoA dehydrogenase b
chr3_+_52442102 0.33 ENSDART00000155455
si:ch211-191c10.1
si:ch211-191c10.1
chr1_+_8601935 0.33 ENSDART00000152367
si:ch211-160d14.6
si:ch211-160d14.6
chr8_+_23147218 0.33 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
gid8a
GID complex subunit 8 homolog a (S. cerevisiae)
chr25_+_14092871 0.33 ENSDART00000067239
guca1g
guanylate cyclase activator 1g
chr2_+_9552456 0.33 ENSDART00000056896
dnajb4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr17_-_12336987 0.32 ENSDART00000172001
snap25b
synaptosomal-associated protein, 25b
chr23_-_18030399 0.32 ENSDART00000136967
pm20d1.1
peptidase M20 domain containing 1, tandem duplicate 1
chr14_+_1240419 0.32 ENSDART00000181248
adad1
adenosine deaminase domain containing 1 (testis-specific)
chr6_-_40697585 0.31 ENSDART00000113196
si:ch211-157b11.14
si:ch211-157b11.14
chr20_-_38836161 0.31 ENSDART00000061358
si:dkey-221h15.4
si:dkey-221h15.4
chr5_+_28041967 0.31 ENSDART00000133641
ogfod2
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr1_-_44638058 0.31 ENSDART00000081835
slc43a1b
solute carrier family 43 (amino acid system L transporter), member 1b
chr9_+_44430974 0.31 ENSDART00000056846
ppp1r1c
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr6_+_54187643 0.31 ENSDART00000056830
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr11_-_3954691 0.30 ENSDART00000182041
pbrm1
polybromo 1
chr11_+_11200550 0.30 ENSDART00000181339
ENSDART00000187116
myom2a
myomesin 2a
chr4_-_20313810 0.30 ENSDART00000136350
dcp1b
decapping mRNA 1B
chr11_-_29685853 0.29 ENSDART00000128468
nr0b1
nuclear receptor subfamily 0, group B, member 1
chr15_+_19885498 0.29 ENSDART00000152123
dyrk1ab
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, b
chr13_-_32635859 0.29 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matn3b
matrilin 3b
chr20_-_39271844 0.29 ENSDART00000192708
clu
clusterin
chr13_-_50139916 0.28 ENSDART00000099475
nid1a
nidogen 1a
chr15_+_19652807 0.28 ENSDART00000134321
ENSDART00000054426
lim2.3
lens intrinsic membrane protein 2.3

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2d

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0042985 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.3 1.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.3 0.8 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.3 0.8 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.2 1.2 GO:0010693 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.2 1.4 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.2 0.6 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.2 0.8 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.2 0.9 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.2 0.6 GO:0003097 renal water homeostasis(GO:0003091) renal water transport(GO:0003097)
0.2 0.5 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.2 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.5 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.0 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 2.1 GO:0090303 positive regulation of wound healing(GO:0090303)
0.2 0.5 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 0.4 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 1.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 1.9 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.4 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.6 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 1.3 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.9 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.1 0.4 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.5 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 1.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 1.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.4 GO:0045730 respiratory burst(GO:0045730)
0.1 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.7 GO:0031643 positive regulation of myelination(GO:0031643)
0.1 0.3 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.9 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 0.2 GO:0010155 regulation of proton transport(GO:0010155)
0.1 0.4 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.5 GO:0003207 cardiac chamber formation(GO:0003207)
0.1 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.6 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.5 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.3 GO:0008584 male gonad development(GO:0008584) water homeostasis(GO:0030104)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.7 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 1.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 2.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.9 GO:0060324 face development(GO:0060324)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.8 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.5 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 1.5 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 0.6 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.7 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.5 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.5 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0006833 water transport(GO:0006833)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.2 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.1 GO:1902914 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.4 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.3 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.9 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0 0.5 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.5 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 0.4 GO:0009408 response to heat(GO:0009408)
0.0 0.6 GO:0045197 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.7 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.5 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.9 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.5 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.6 GO:0060914 heart formation(GO:0060914)
0.0 0.5 GO:0030901 midbrain development(GO:0030901)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.4 GO:0097541 axonemal basal plate(GO:0097541)
0.1 2.3 GO:0031430 M band(GO:0031430)
0.1 1.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0008352 katanin complex(GO:0008352)
0.1 0.7 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 1.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0016586 RSC complex(GO:0016586)
0.0 0.8 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.4 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 2.1 GO:0016936 galactoside binding(GO:0016936)
0.2 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.8 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.6 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.4 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 3.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.3 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.1 0.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.7 GO:0015250 water channel activity(GO:0015250)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.9 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 2.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.5 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.5 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.0 0.3 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0033549 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 2.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.7 PID P73PATHWAY p73 transcription factor network
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4 2.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.8 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation