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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Z-value: 0.69

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Transcription factors associated with meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

Gene Symbol Gene ID Gene Info
meis2b
ENSDARG00000077840 Meis homeobox 2a
meis2a
ENSDARG00000098240 Meis homeobox 2a
FO834857.1
ENSDARG00000112895 homeobox protein TGIF2-like
pknox1.1
ENSDARG00000018765 pbx/knotted 1 homeobox 1.1
pknox1.2
ENSDARG00000036542 pbx/knotted 1 homeobox 1.2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FO834857.1dr11_v1_chr6_-_1820606_18206060.831.9e-05Click!
meis2bdr11_v1_chr20_-_10118818_10118818-0.672.3e-03Click!
meis2adr11_v1_chr17_+_52822831_52822831-0.663.0e-03Click!
pknox1.2dr11_v1_chr1_-_46981134_46981134-0.653.4e-03Click!
pknox1.1dr11_v1_chr9_+_19529951_195299510.312.1e-01Click!

Activity profile of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Sorted Z-values of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_32385989 2.65 ENSDART00000143716
ENSDART00000098850
lipg
lipase, endothelial
chr2_-_11027258 2.10 ENSDART00000081072
ENSDART00000193824
ENSDART00000187036
ENSDART00000097741
ssbp3a
single stranded DNA binding protein 3a
chr12_-_48168135 1.81 ENSDART00000186624
pald1a
phosphatase domain containing, paladin 1a
chr4_-_20081621 1.80 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr14_-_41468892 1.74 ENSDART00000173099
ENSDART00000003170
mid1ip1l
MID1 interacting protein 1, like
chr3_+_7771420 1.48 ENSDART00000156809
ENSDART00000156309
hook2
hook microtubule-tethering protein 2
chr5_-_12587053 1.48 ENSDART00000162780
vsig10
V-set and immunoglobulin domain containing 10
chr20_+_14968031 1.45 ENSDART00000151805
ENSDART00000151448
ENSDART00000063874
ENSDART00000190910
vamp4
vesicle-associated membrane protein 4
chr22_-_37834312 1.38 ENSDART00000076128
ppp1r2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr25_+_22319940 1.38 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cyp11a1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr5_-_32489796 1.35 ENSDART00000168870
gpr107
G protein-coupled receptor 107
chr1_+_2301961 1.34 ENSDART00000108919
ENSDART00000143361
ENSDART00000142944
farp1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr17_-_7792376 1.33 ENSDART00000064655
zbtb2a
zinc finger and BTB domain containing 2a
chr8_+_25959940 1.32 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
si:dkey-72l14.4
chr23_+_13528053 1.28 ENSDART00000162217
uckl1b
uridine-cytidine kinase 1-like 1b
chr15_-_28587490 1.27 ENSDART00000186196
ssh2a
slingshot protein phosphatase 2a
chr5_-_69482891 1.25 ENSDART00000109487
CABZ01032476.1

chr15_-_28587147 1.23 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr7_-_26262978 1.20 ENSDART00000137769
ap1s1
adaptor-related protein complex 1, sigma 1 subunit
chr7_-_26263183 1.19 ENSDART00000079357
ENSDART00000190369
ENSDART00000193154
ENSDART00000101109
ap1s1
adaptor-related protein complex 1, sigma 1 subunit
chr4_+_27898833 1.12 ENSDART00000146099
cerk
ceramide kinase
chr11_-_10456387 1.10 ENSDART00000011087
ENSDART00000081827
ect2
epithelial cell transforming 2
chr12_+_33320884 1.10 ENSDART00000188988
csnk1db
casein kinase 1, delta b
chr25_-_2723682 1.06 ENSDART00000113382
adpgk
ADP-dependent glucokinase
chr18_+_39487486 1.06 ENSDART00000126978
acadl
acyl-CoA dehydrogenase long chain
chr9_+_27876146 1.02 ENSDART00000133997
armc8
armadillo repeat containing 8
chr14_-_34605607 1.00 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr6_-_41135215 1.00 ENSDART00000001861
slc6a22.1
solute carrier family 6 member 22, tandem duplicate 1
chr23_+_21492151 1.00 ENSDART00000025487
icmt
isoprenylcysteine carboxyl methyltransferase
chr24_-_36095526 1.00 ENSDART00000158145
CABZ01075509.1

chr2_-_27651674 0.99 ENSDART00000177402
tgs1
trimethylguanosine synthase 1
chr19_-_30800004 0.99 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
trit1
tRNA isopentenyltransferase 1
chr23_+_39963599 0.97 ENSDART00000166539
fyco1a
FYVE and coiled-coil domain containing 1a
chr10_+_28160265 0.97 ENSDART00000022484
rnft1
ring finger protein, transmembrane 1
chr5_-_13766651 0.96 ENSDART00000134064
mxd1
MAX dimerization protein 1
chr14_+_30340251 0.94 ENSDART00000148448
mtus1a
microtubule associated tumor suppressor 1a
chr5_-_23675222 0.94 ENSDART00000135153
TBC1D8B
si:dkey-110k5.6
chr21_-_14832369 0.91 ENSDART00000144859
pus1
pseudouridylate synthase 1
chr21_-_41065369 0.89 ENSDART00000143749
larsb
leucyl-tRNA synthetase b
chr18_+_35128685 0.89 ENSDART00000151579
si:ch211-195m9.3
si:ch211-195m9.3
chr14_-_6402769 0.89 ENSDART00000121552
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr5_-_39805620 0.89 ENSDART00000137801
rasgef1ba
RasGEF domain family, member 1Ba
chr5_+_27137473 0.87 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr15_+_41815703 0.86 ENSDART00000059508
pxylp1
2-phosphoxylose phosphatase 1
chr17_+_19630068 0.85 ENSDART00000182619
rgs7a
regulator of G protein signaling 7a
chr23_+_33963619 0.85 ENSDART00000140666
ENSDART00000084792
plpbp
pyridoxal phosphate binding protein
chr13_+_46803979 0.84 ENSDART00000159260
CU695232.1

chr5_-_41124241 0.82 ENSDART00000083561
mtmr12
myotubularin related protein 12
chr14_-_33481428 0.80 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr14_-_34605804 0.79 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr14_-_38889840 0.79 ENSDART00000035779
zgc:101583
zgc:101583
chr19_-_46032556 0.77 ENSDART00000167185
nup153
nucleoporin 153
chr17_-_23673864 0.77 ENSDART00000104738
ENSDART00000128958
ptena
phosphatase and tensin homolog A
chr5_-_39805874 0.76 ENSDART00000176202
ENSDART00000191683
rasgef1ba
RasGEF domain family, member 1Ba
chr25_-_36261836 0.76 ENSDART00000179411
dus2
dihydrouridine synthase 2
chr7_-_56766100 0.75 ENSDART00000189934
csnk2a2a
casein kinase 2, alpha prime polypeptide a
chr8_-_410728 0.74 ENSDART00000151255
trim36
tripartite motif containing 36
chr11_-_34478225 0.72 ENSDART00000189604
xxylt1
xyloside xylosyltransferase 1
chr16_+_33144306 0.71 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr14_-_33945692 0.70 ENSDART00000168546
ENSDART00000189778
zdhhc24
zinc finger, DHHC-type containing 24
chr16_+_50434668 0.68 ENSDART00000193500
IGLON5
zgc:110372
chr12_+_28888975 0.68 ENSDART00000076362
phkg2
phosphorylase kinase, gamma 2 (testis)
chr10_+_36695597 0.67 ENSDART00000169015
ENSDART00000171392
rab6a
RAB6A, member RAS oncogene family
chr23_-_31060350 0.66 ENSDART00000145598
ENSDART00000191491
si:ch211-197l9.5
si:ch211-197l9.5
chr10_-_35177257 0.66 ENSDART00000077426
pom121
POM121 transmembrane nucleoporin
chr17_+_49095662 0.65 ENSDART00000179545
tiam2a
T cell lymphoma invasion and metastasis 2a
chr19_+_42231431 0.65 ENSDART00000102698
jtb
jumping translocation breakpoint
chr8_-_18899427 0.64 ENSDART00000079840
rorca
RAR-related orphan receptor C a
chr19_-_12212692 0.64 ENSDART00000142077
ENSDART00000151599
ENSDART00000140834
ENSDART00000078781
znf706
zinc finger protein 706
chr17_-_24890843 0.64 ENSDART00000184984
ENSDART00000135569
ENSDART00000193661
gale
UDP-galactose-4-epimerase
chr18_+_14619544 0.64 ENSDART00000010821
utp4
UTP4, small subunit processome component
chr18_-_46010 0.63 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_-_51072406 0.63 ENSDART00000083777
ago3a
argonaute RISC catalytic component 3a
chr3_+_29082267 0.63 ENSDART00000145615
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr6_+_33537267 0.63 ENSDART00000040334
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr15_+_23528010 0.63 ENSDART00000152786
si:dkey-182i3.8
si:dkey-182i3.8
chr8_-_4760723 0.62 ENSDART00000064201
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae)
chr5_-_20135679 0.61 ENSDART00000079402
usp30
ubiquitin specific peptidase 30
chr13_-_24396003 0.60 ENSDART00000016211
tbp
TATA box binding protein
chr8_-_13678415 0.60 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
si:dkey-258f14.3
chr10_-_25328814 0.60 ENSDART00000123820
tmem135
transmembrane protein 135
chr10_+_10738880 0.60 ENSDART00000004181
slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr3_-_40836081 0.60 ENSDART00000143135
wipi2
WD repeat domain, phosphoinositide interacting 2
chr15_-_20528494 0.60 ENSDART00000048423
timm50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr6_+_21005725 0.58 ENSDART00000041370
cx44.2
connexin 44.2
chr18_-_41160975 0.58 ENSDART00000187517
CABZ01005876.1

chr9_+_34151367 0.58 ENSDART00000143991
gpr161
G protein-coupled receptor 161
chr20_-_28433990 0.58 ENSDART00000182824
ENSDART00000193381
wdr21
WD repeat domain 21
chr9_+_6009077 0.56 ENSDART00000057484
st6gal2a
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a
chr22_-_21897203 0.56 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr8_-_41519064 0.56 ENSDART00000098578
ENSDART00000112214
golga1
golgin A1
chr22_+_18316144 0.56 ENSDART00000137985
gatad2ab
GATA zinc finger domain containing 2Ab
chr20_+_27712714 0.55 ENSDART00000008306
zbtb1
zinc finger and BTB domain containing 1
chr13_-_24396199 0.55 ENSDART00000181093
tbp
TATA box binding protein
chr23_-_29667544 0.54 ENSDART00000059339
clstn1
calsyntenin 1
chr20_+_27713210 0.54 ENSDART00000132222
zbtb1
zinc finger and BTB domain containing 1
chr22_-_37796998 0.54 ENSDART00000124742
ENSDART00000191232
acap2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr8_-_41519234 0.53 ENSDART00000167283
ENSDART00000180666
golga1
golgin A1
chr20_+_21391181 0.53 ENSDART00000185158
ENSDART00000049586
ENSDART00000024922
jag2b
jagged 2b
chr7_+_41887429 0.53 ENSDART00000115090
gpt2
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr22_+_2769236 0.53 ENSDART00000141836
si:dkey-20i20.10
si:dkey-20i20.10
chr15_-_506010 0.52 ENSDART00000155472
nudt8
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr17_-_14780578 0.52 ENSDART00000154690
si:ch211-266o15.1
si:ch211-266o15.1
chr20_-_165818 0.51 ENSDART00000123860
si:ch211-241j12.3
si:ch211-241j12.3
chr15_-_20125331 0.50 ENSDART00000152355
med13b
mediator complex subunit 13b
chr13_+_24396666 0.50 ENSDART00000139197
ENSDART00000101200
zgc:153169
zgc:153169
chr22_-_17677947 0.49 ENSDART00000139911
tjp3
tight junction protein 3
chr16_+_33144112 0.49 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr15_+_17345609 0.49 ENSDART00000111753
vmp1
vacuole membrane protein 1
chr12_+_18916285 0.48 ENSDART00000127536
cbx7b
chromobox homolog 7b
chr10_+_20590190 0.47 ENSDART00000131819
letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr4_+_9612574 0.47 ENSDART00000150336
ENSDART00000041289
ENSDART00000150828
tmem243b
transmembrane protein 243, mitochondrial b
chr5_+_44346691 0.47 ENSDART00000034523
tars
threonyl-tRNA synthetase
chr3_+_28576173 0.47 ENSDART00000151189
sept12
septin 12
chr14_+_29200772 0.47 ENSDART00000166608
TENM2
si:dkey-34l15.2
chr16_-_32672883 0.47 ENSDART00000124515
ENSDART00000190920
ENSDART00000188776
pnisr
PNN-interacting serine/arginine-rich protein
chr2_+_2957515 0.46 ENSDART00000160715
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr22_-_16377666 0.45 ENSDART00000161878
ttc39c
tetratricopeptide repeat domain 39C
chr5_-_37103487 0.45 ENSDART00000149211
il13ra2
interleukin 13 receptor, alpha 2
chr21_-_25612658 0.45 ENSDART00000115276
fibpb
fibroblast growth factor (acidic) intracellular binding protein b
chr16_-_44673851 0.45 ENSDART00000015139
dcaf13
ddb1 and cul4 associated factor 13
chr16_+_20167811 0.44 ENSDART00000004031
hacl1
2-hydroxyacyl-CoA lyase 1
chr17_-_50040927 0.44 ENSDART00000184304
FO834825.1

chr23_-_4019928 0.44 ENSDART00000021062
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr15_+_23528310 0.44 ENSDART00000152523
si:dkey-182i3.8
si:dkey-182i3.8
chr17_+_50074372 0.44 ENSDART00000113644
vps39
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr22_-_16377960 0.44 ENSDART00000168170
ttc39c
tetratricopeptide repeat domain 39C
chr6_+_38773376 0.43 ENSDART00000078128
ENSDART00000184053
ube3a
ubiquitin protein ligase E3A
chr20_-_20270191 0.43 ENSDART00000009356
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr4_+_15006217 0.43 ENSDART00000090837
zc3hc1
zinc finger, C3HC-type containing 1
chr17_+_33999630 0.43 ENSDART00000167085
ENSDART00000155030
ENSDART00000168522
ENSDART00000191799
ENSDART00000189684
ENSDART00000153942
ENSDART00000187272
ENSDART00000127692
gphna
gephyrin a
chr5_+_72145468 0.43 ENSDART00000148626
abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr7_-_56766973 0.42 ENSDART00000020967
csnk2a2a
casein kinase 2, alpha prime polypeptide a
chr1_+_29183962 0.42 ENSDART00000113735
cars2
cysteinyl-tRNA synthetase 2, mitochondrial
chr10_+_20589969 0.42 ENSDART00000183042
letm2
leucine zipper-EF-hand containing transmembrane protein 2
chr19_-_81477 0.42 ENSDART00000159815
hnrnpr
heterogeneous nuclear ribonucleoprotein R
chr23_-_4019699 0.42 ENSDART00000159780
slc9a8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr23_-_45955177 0.42 ENSDART00000165963
ENSDART00000186649
ENSDART00000185773
LO017850.1

chr14_-_16082806 0.42 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr12_-_17201028 0.41 ENSDART00000020541
lipf
lipase, gastric
chr2_+_27855346 0.41 ENSDART00000175159
ENSDART00000192645
buc
bucky ball
chr18_+_15937610 0.41 ENSDART00000061134
ENSDART00000154505
itpr2
inositol 1,4,5-trisphosphate receptor, type 2
chr8_-_31384607 0.41 ENSDART00000164134
ENSDART00000024872
creb3l3l
cAMP responsive element binding protein 3-like 3 like
chr13_+_13945218 0.41 ENSDART00000089501
ENSDART00000142997
eif2ak3
eukaryotic translation initiation factor 2-alpha kinase 3
chr13_-_42749916 0.41 ENSDART00000140019
capn2a
calpain 2, (m/II) large subunit a
chr20_+_47953047 0.41 ENSDART00000079734
hadhaa
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a
chr2_-_41723487 0.41 ENSDART00000170171
zgc:110158
zgc:110158
chr11_-_16021424 0.40 ENSDART00000193291
ENSDART00000170731
ENSDART00000104107
zgc:173544
zgc:173544
chr9_+_21536122 0.40 ENSDART00000182266
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr20_+_33924235 0.40 ENSDART00000146292
ENSDART00000139609
lmx1a
LIM homeobox transcription factor 1, alpha
chr18_-_16907436 0.40 ENSDART00000146464
swap70b
switching B cell complex subunit SWAP70b
chr16_-_42770064 0.40 ENSDART00000112879
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr3_-_27880229 0.39 ENSDART00000151404
abat
4-aminobutyrate aminotransferase
chr24_+_37484661 0.39 ENSDART00000165125
ENSDART00000109221
wdr90
WD repeat domain 90
chr9_+_21535885 0.39 ENSDART00000141408
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr12_-_10505986 0.39 ENSDART00000152672
zgc:152977
zgc:152977
chr11_+_5880562 0.39 ENSDART00000129663
ENSDART00000130768
ENSDART00000160909
dazap1
DAZ associated protein 1
chr5_-_37341044 0.39 ENSDART00000084675
wdr44
WD repeat domain 44
chr3_-_50147160 0.39 ENSDART00000191341
btr02
bloodthirsty-related gene family, member 2
chr14_-_689841 0.38 ENSDART00000125969
ube2ka
ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast)
chr13_+_35765317 0.38 ENSDART00000100156
ENSDART00000167650
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr6_+_40952031 0.38 ENSDART00000189219
patz1
POZ (BTB) and AT hook containing zinc finger 1
chr7_-_59159253 0.38 ENSDART00000159285
haus6
HAUS augmin-like complex, subunit 6
chr1_+_24382651 0.37 ENSDART00000123789
qdprb2
quinoid dihydropteridine reductase b2
chr5_-_22082918 0.37 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr7_+_16352924 0.37 ENSDART00000158972
mpped2a
metallophosphoesterase domain containing 2a
chr2_+_30489846 0.37 ENSDART00000145732
march6
membrane-associated ring finger (C3HC4) 6
chr8_-_17184482 0.37 ENSDART00000025803
pola2
polymerase (DNA directed), alpha 2
chr11_+_26375979 0.37 ENSDART00000087652
ENSDART00000171748
ENSDART00000103513
ENSDART00000165931
ENSDART00000170043
cpne1
rbm12
copine I
RNA binding motif protein 12
chr21_-_38153824 0.37 ENSDART00000151226
klf5l
Kruppel-like factor 5 like
chr20_+_32478151 0.36 ENSDART00000145269
ostm1
osteopetrosis associated transmembrane protein 1
chr22_+_1481307 0.36 ENSDART00000177429
si:ch211-255f4.2
si:ch211-255f4.2
chr9_-_25366541 0.36 ENSDART00000021672
epc2
enhancer of polycomb homolog 2 (Drosophila)
chr13_+_45524475 0.35 ENSDART00000074567
ENSDART00000019113
maco1b
macoilin 1b
chr5_-_35200590 0.35 ENSDART00000051271
fcho2
FCH domain only 2
chr23_+_44427188 0.35 ENSDART00000160207
eif4e2rs1
eukaryotic translation initiation factor 4E family member 2 related sequence 1
chr6_+_4371137 0.35 ENSDART00000168973
rbm26
RNA binding motif protein 26
chr8_+_23639124 0.35 ENSDART00000083108
nt5dc2
5'-nucleotidase domain containing 2
chr2_-_38117538 0.34 ENSDART00000013676
chd8
chromodomain helicase DNA binding protein 8
chr5_-_21030934 0.34 ENSDART00000133461
ENSDART00000098667
camk2b1
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr10_+_44955106 0.34 ENSDART00000185837
il1b
interleukin 1, beta
chr4_-_16124417 0.34 ENSDART00000128079
ENSDART00000077664
atp2b1a
ATPase plasma membrane Ca2+ transporting 1a
chr9_-_12575776 0.34 ENSDART00000128931
ENSDART00000182695
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr7_+_21768452 0.34 ENSDART00000127719
kdm6ba
lysine (K)-specific demethylase 6B, a
chr6_+_4370935 0.34 ENSDART00000192368
rbm26
RNA binding motif protein 26
chr8_+_44623540 0.34 ENSDART00000141513
grk5l
G protein-coupled receptor kinase 5 like
chr8_+_12951155 0.33 ENSDART00000081601
cept1a
choline/ethanolamine phosphotransferase 1a
chr7_+_41812636 0.33 ENSDART00000174333
orc6
origin recognition complex, subunit 6
chr18_+_907266 0.33 ENSDART00000171729
pkma
pyruvate kinase M1/2a
chr18_-_49286381 0.33 ENSDART00000174248
ENSDART00000174038
si:zfos-464b6.2
si:zfos-464b6.2
chr5_-_3991655 0.33 ENSDART00000159368
myo19
myosin XIX
chr5_+_15992655 0.33 ENSDART00000182148
znrf3
zinc and ring finger 3
chr13_-_18011168 0.32 ENSDART00000144813
march8
membrane-associated ring finger (C3HC4) 8
chr9_-_12575569 0.32 ENSDART00000102419
igf2bp2a
insulin-like growth factor 2 mRNA binding protein 2a
chr17_+_38030327 0.32 ENSDART00000085481
slc25a21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr3_+_17616201 0.32 ENSDART00000156775
rab5c
RAB5C, member RAS oncogene family
chr20_-_28433616 0.32 ENSDART00000169289
wdr21
WD repeat domain 21
chr17_+_47174525 0.32 ENSDART00000156831
CLIP4
si:dkeyp-47f9.4
chr1_-_47122058 0.32 ENSDART00000159925
ENSDART00000101143
ENSDART00000176803
mhc1zea
major histocompatibility complex class I ZEA
chr7_+_34794829 0.32 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of meis2a+meis2b_FO834857.1_pknox1.1+pknox1.2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0090161 Golgi ribbon formation(GO:0090161)
0.3 1.4 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 1.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 0.6 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.2 0.2 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.2 1.0 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 1.0 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.2 0.9 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 0.9 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.2 2.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 0.8 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.2 1.2 GO:0044211 CTP salvage(GO:0044211)
0.1 0.4 GO:0042040 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.6 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.4 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.1 0.4 GO:0021824 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.1 0.4 GO:0045041 positive regulation of interleukin-6 production(GO:0032755) protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.3 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.1 1.1 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.3 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.1 0.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.3 GO:2000660 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.1 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 1.2 GO:0006405 RNA export from nucleus(GO:0006405)
0.1 0.3 GO:0032801 receptor catabolic process(GO:0032801)
0.1 1.9 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.4 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.1 1.3 GO:0032418 lysosome localization(GO:0032418)
0.1 0.6 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.7 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 0.4 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.1 0.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.6 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.4 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 0.2 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.3 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.6 GO:0018410 C-terminal protein amino acid modification(GO:0018410)
0.1 0.3 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.5 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.6 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.5 GO:0030104 water homeostasis(GO:0030104)
0.0 0.3 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.2 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.2 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 1.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.2 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.2 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.4 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 1.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.2 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 1.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 2.0 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0014015 positive regulation of gliogenesis(GO:0014015)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.9 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 2.1 GO:0006400 tRNA modification(GO:0006400)
0.0 1.1 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.5 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.6 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.2 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 2.3 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.1 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272) nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.3 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.0 GO:0070814 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.1 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.7 GO:0051028 mRNA transport(GO:0051028)
0.0 0.0 GO:0071042 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.5 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.2 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.4 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.0 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.7 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0035331 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.6 GO:0006096 glycolytic process(GO:0006096)
0.0 0.1 GO:0009437 carnitine metabolic process(GO:0009437)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.3 1.3 GO:0034657 GID complex(GO:0034657)
0.1 1.8 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.4 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 1.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.6 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.6 GO:0032021 NELF complex(GO:0032021)
0.1 0.3 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 1.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0032019 mitochondrial cloud(GO:0032019)
0.1 1.0 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 1.0 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0016605 PML body(GO:0016605)
0.0 1.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.4 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.7 GO:0005902 microvillus(GO:0005902)
0.0 0.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.4 1.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.4 1.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 2.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 0.6 GO:0003978 UDP-glucose 4-epimerase activity(GO:0003978)
0.2 0.8 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.2 1.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 1.2 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.2 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.4 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 0.6 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.9 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.0 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.3 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.6 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 3.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 1.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.8 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 1.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 4.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 3.7 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID ATM PATHWAY ATM pathway
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 1.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase