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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for meox2b

Z-value: 0.47

Motif logo

Transcription factors associated with meox2b

Gene Symbol Gene ID Gene Info
ENSDARG00000061818 mesenchyme homeobox 2b
ENSDARG00000116206 mesenchyme homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meox2bdr11_v1_chr19_+_31183495_311834950.608.9e-03Click!

Activity profile of meox2b motif

Sorted Z-values of meox2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_+_17269849 1.77 ENSDART00000017605
sperm associated antigen 6
chr10_-_29236860 1.73 ENSDART00000111620
coiled-coil domain containing 83
chr23_-_32404022 1.44 ENSDART00000156387
ENSDART00000155508
si:ch211-66i15.4
chr17_+_21295132 1.38 ENSDART00000103845
enolase family member 4
chr6_-_40352215 1.30 ENSDART00000103992
tubulin tyrosine ligase-like family, member 3
chr23_-_23401305 1.28 ENSDART00000078936
hairy-related 9
chr15_+_34988148 1.25 ENSDART00000076269
coiled-coil domain containing 105
chr25_-_16581233 1.24 ENSDART00000155312
structural maintenance of chromosomes 1B
chr9_-_48407408 1.18 ENSDART00000058248
zgc:172182
chr5_+_6954162 1.13 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr11_-_37997419 1.10 ENSDART00000102870
solute carrier family 41 (magnesium transporter), member 1
chr20_-_7072487 1.09 ENSDART00000145954
si:ch211-121a2.2
chr5_+_44944778 1.04 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr17_+_30205258 0.99 ENSDART00000076596
ENSDART00000153795
spermatogenesis associated 17
chr5_-_10007897 0.98 ENSDART00000109052
Danio rerio uncharacterized LOC799523 (LOC799523), mRNA.
chr4_+_17279966 0.97 ENSDART00000067005
ENSDART00000137487
branched chain amino-acid transaminase 1, cytosolic
chr3_+_28953274 0.96 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr8_+_49117518 0.94 ENSDART00000079631
RAD21 cohesin complex component like 1
chr21_-_25618175 0.89 ENSDART00000133512
FOS-like antigen 1b
chr17_+_15433671 0.86 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr17_+_15433518 0.84 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr22_-_25469751 0.84 ENSDART00000171670

chr2_+_49799470 0.83 ENSDART00000146325
si:ch211-190k17.19
chr19_+_43604643 0.83 ENSDART00000151168
si:ch211-199g17.9
chr25_+_26895394 0.83 ENSDART00000155820
si:dkey-42p14.3
chr20_+_27691307 0.81 ENSDART00000153299
si:dkey-1h6.8
chr23_+_19813677 0.79 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr7_-_20758825 0.79 ENSDART00000156717
ENSDART00000182629
ENSDART00000179801
chromodomain helicase DNA binding protein 3
chr24_-_39610585 0.78 ENSDART00000066506
cytochrome c oxidase subunit VIb polypeptide 1
chr24_-_26399623 0.77 ENSDART00000112317
zgc:194621
chr14_-_15171435 0.77 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr1_-_46244523 0.77 ENSDART00000143908
si:ch211-138g9.3
chr24_+_12989727 0.77 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr4_-_815871 0.76 ENSDART00000067455
dihydropyrimidinase-like 5b
chr15_-_20933574 0.76 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
ubiquitin specific peptidase 2a
chr10_+_6884627 0.75 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr14_-_858985 0.74 ENSDART00000148687
ENSDART00000149375
solute carrier family 34 (type II sodium/phosphate cotransporter), member 1a
chr21_+_43404945 0.74 ENSDART00000142234
FERM domain containing 7
chr8_-_13046089 0.74 ENSDART00000137784
si:dkey-208b23.5
chr19_+_43604256 0.74 ENSDART00000151080
ENSDART00000110305
si:ch211-199g17.9
chr15_-_45110011 0.74 ENSDART00000182047
ENSDART00000188662

chr15_+_36309070 0.74 ENSDART00000157034
geminin coiled-coil domain containing
chr20_+_36629173 0.73 ENSDART00000161241
epoxide hydrolase 1, microsomal (xenobiotic)
chr6_+_41191482 0.72 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr16_-_54455573 0.71 ENSDART00000075275
pyruvate kinase L/R
chr9_-_7652792 0.70 ENSDART00000137957
DnaJ (Hsp40) homolog, subfamily B, member 2
chr10_+_39084354 0.70 ENSDART00000158245
si:ch73-1a9.3
chr19_+_43297546 0.70 ENSDART00000168002
lysosomal protein transmembrane 5
chr4_-_22472653 0.69 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
lysine (K)-specific methyltransferase 2E
chr4_-_72544805 0.68 ENSDART00000110261
zgc:175107
chr1_+_22691256 0.67 ENSDART00000017413
zinc finger, MYND-type containing 10
chr5_+_42400777 0.67 ENSDART00000183114

chr21_-_22827548 0.66 ENSDART00000079161
angiopoietin-like 5
chr12_-_35830625 0.65 ENSDART00000180028

chr6_+_3280939 0.65 ENSDART00000151359
lysine (K)-specific demethylase 4A, genome duplicate a
chr19_+_31873308 0.63 ENSDART00000146560
ENSDART00000133045
si:dkeyp-34f6.4
chr16_+_6021908 0.63 ENSDART00000163786

chr21_+_45502621 0.62 ENSDART00000166719
si:dkey-223p19.2
chr13_-_37620091 0.62 ENSDART00000135875
ENSDART00000193270
ENSDART00000018064
zgc:152791
chr10_+_31222433 0.62 ENSDART00000185080
transmembrane protein 218
chr8_+_2438638 0.61 ENSDART00000141263
si:ch211-220d9.3
chr17_+_12285285 0.61 ENSDART00000154336
Pim proto-oncogene, serine/threonine kinase, related 174
chr1_-_44701313 0.60 ENSDART00000193926
si:dkey-28b4.8
chr6_-_31361546 0.60 ENSDART00000027550
adenylate kinase 4
chr14_+_33329420 0.59 ENSDART00000171090
ENSDART00000164062
sosondowah ankyrin repeat domain family d
chr20_-_51355465 0.59 ENSDART00000151620
ENSDART00000151690
ENSDART00000110289
t-complex-associated-testis-expressed 1
chr11_-_2478374 0.59 ENSDART00000173205
si:ch73-267c23.10
chr19_-_41069573 0.58 ENSDART00000111982
ENSDART00000193142
sarcoglycan, epsilon
chr10_+_40324395 0.58 ENSDART00000147205
glycolipid transfer protein b
chr24_+_24831727 0.57 ENSDART00000080969
tripartite motif containing 55b
chr25_-_28600433 0.57 ENSDART00000138980
ATP/GTP binding protein-like 2
chr8_+_7144066 0.57 ENSDART00000146306
solute carrier family 6 (neurotransmitter transporter), member 6a
chr12_+_47698356 0.57 ENSDART00000112010
leucine zipper, putative tumor suppressor 2b
chr22_+_2860260 0.57 ENSDART00000106221
si:dkey-20i20.2
chr3_+_17537352 0.57 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr8_-_7475917 0.56 ENSDART00000082157
GATA binding protein 1b
chr21_+_30355767 0.56 ENSDART00000189948

chr13_+_30903816 0.55 ENSDART00000191727
excision repair cross-complementation group 6
chr8_+_22930627 0.55 ENSDART00000187860
synaptophysin a
chr1_+_52929185 0.55 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr10_-_9410068 0.55 ENSDART00000041382
MORN repeat containing 5
chr18_+_402048 0.54 ENSDART00000166345
glucose-6-phosphate isomerase b
chr15_-_22251089 0.54 ENSDART00000153646
si:ch211-286b4.4
chr3_-_40202607 0.54 ENSDART00000074757
zinc finger protein 598
chr25_+_3327071 0.54 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr20_+_39457598 0.54 ENSDART00000140931
ENSDART00000156176
Pim proto-oncogene, serine/threonine kinase, related 128
chr16_+_23961276 0.53 ENSDART00000192754
apolipoprotein Eb
chr13_-_42400647 0.53 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr7_+_72460911 0.53 ENSDART00000160682
ENSDART00000168532
HECT domain E3 ubiquitin protein ligase 4
chr22_+_18187857 0.53 ENSDART00000166300
myocyte enhancer factor 2b
chr16_+_4695075 0.52 ENSDART00000039054
mitochondrial trans-2-enoyl-CoA reductase
chr15_-_4969525 0.52 ENSDART00000157223
lipoyl(octanoyl) transferase 2
chr8_+_21384288 0.52 ENSDART00000079263
forkhead-associated (FHA) phosphopeptide binding domain 1
chr15_-_28596507 0.52 ENSDART00000156800
si:ch211-225b7.5
chr24_+_40860320 0.52 ENSDART00000161351
golgi reassembly stacking protein 1b
chr8_-_34762163 0.50 ENSDART00000114080
SET domain containing 1B, b
chr5_-_25723079 0.50 ENSDART00000014013
guanine deaminase
chr6_-_37469775 0.50 ENSDART00000156546
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr23_+_40460333 0.50 ENSDART00000184658
SOGA family member 3b
chr9_-_20372977 0.49 ENSDART00000113418
immunoglobulin superfamily, member 3
chr12_+_24952902 0.49 ENSDART00000189086
ENSDART00000014868
calmodulin 3a (phosphorylase kinase, delta)
chr13_-_37545487 0.49 ENSDART00000131269
synaptotagmin XVI
chr7_-_28148310 0.49 ENSDART00000044208
LIM domain only 1
chr24_+_12945803 0.49 ENSDART00000005105
proteasome activator subunit 1
chr11_-_3987885 0.49 ENSDART00000058735
glycosyltransferase 8 domain containing 1
chr9_-_30576522 0.49 ENSDART00000101085
MORC family CW-type zinc finger 3a
chr17_+_7513673 0.48 ENSDART00000156674
kelch-like family member 10b, tandem duplicate 1
chr25_+_3326885 0.48 ENSDART00000104866
lactate dehydrogenase Bb
chr17_+_6625717 0.48 ENSDART00000190753
ENSDART00000181298

chr7_-_20103384 0.48 ENSDART00000052902
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr1_-_46981134 0.48 ENSDART00000130607
pbx/knotted 1 homeobox 1.2
chr3_-_60175470 0.48 ENSDART00000156597
si:ch73-364h19.1
chr4_+_11384891 0.48 ENSDART00000092381
ENSDART00000186577
ENSDART00000191054
ENSDART00000191584
piccolo presynaptic cytomatrix protein a
chr19_+_233143 0.48 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr22_+_1796057 0.48 ENSDART00000170834
zinc finger protein 1179
chr3_+_18398876 0.48 ENSDART00000141100
ENSDART00000138107
ribosomal protein S2
chr6_+_46258866 0.48 ENSDART00000134584
zgc:162324
chr16_+_11029762 0.47 ENSDART00000091183
Ets2 repressor factor like 3
chr2_+_19578079 0.47 ENSDART00000144413
Pim proto-oncogene, serine/threonine kinase, related 50
chr13_+_27232848 0.47 ENSDART00000138043
Ras and Rab interactor 2
chr7_+_34687969 0.47 ENSDART00000182013
ENSDART00000188255
ENSDART00000182728
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr1_+_44003654 0.47 ENSDART00000131337
si:dkey-22i16.10
chr1_-_17715493 0.47 ENSDART00000133027
si:dkey-256e7.8
chr3_-_24456451 0.46 ENSDART00000024480
ENSDART00000156814
BAI1-associated protein 2-like 2a
chr8_+_21353878 0.46 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr3_+_24458899 0.46 ENSDART00000156655
chromobox homolog 6b
chr1_-_58562129 0.46 ENSDART00000159070
solute carrier family 27 (fatty acid transporter), member 1b
chr22_-_15578402 0.46 ENSDART00000062986
hematopoietic SH2 domain containing
chr4_-_69189894 0.46 ENSDART00000169596
si:ch211-209j12.1
chr18_+_20838786 0.46 ENSDART00000138692
tetratricopeptide repeat domain 23
chr5_+_63668735 0.46 ENSDART00000134261
ENSDART00000097330
dynamin 1b
chr12_-_20795867 0.46 ENSDART00000152835
ENSDART00000153424
NME/NM23 nucleoside diphosphate kinase 2a
chr20_-_9095105 0.45 ENSDART00000140792
OMA1 zinc metallopeptidase
chr2_+_33747509 0.45 ENSDART00000134187
si:dkey-31m5.5
chr23_-_24493768 0.45 ENSDART00000135559
ENSDART00000046933
sulfotransferase family 1, cytosolic sulfotransferase 5
chr16_+_40576679 0.45 ENSDART00000169412
ENSDART00000193464
cyclin E2
chr15_-_21877726 0.45 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr1_-_47071979 0.44 ENSDART00000160817
intersectin 1 (SH3 domain protein)
chr25_+_4979446 0.44 ENSDART00000154131
ENSDART00000155537
si:ch73-265h17.1
chr13_+_22295905 0.44 ENSDART00000180133
ENSDART00000181125
ubiquitin specific peptidase 54a
chr22_-_547748 0.44 ENSDART00000037455
ENSDART00000140101
cyclin D3
chr1_+_22174251 0.44 ENSDART00000137429
dynein, axonemal, heavy chain 6
chr14_+_6546516 0.44 ENSDART00000097214
ADAM metallopeptidase domain 19b
chr22_+_2937485 0.43 ENSDART00000082222
ENSDART00000135507
ENSDART00000143258
centrosomal protein 19
chr3_+_26135502 0.43 ENSDART00000146979
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr20_-_1378514 0.43 ENSDART00000181830
scavenger receptor class A, member 5 (putative)
chr1_+_52662203 0.43 ENSDART00000141530
oxysterol binding protein
chr14_+_41345175 0.42 ENSDART00000086104
NADPH oxidase 1
chr4_-_17642168 0.42 ENSDART00000007030
kelch-like family, member 42
chr9_-_889567 0.42 ENSDART00000155921
si:ch73-250a16.5
chr12_+_27117609 0.42 ENSDART00000076154
homeobox B8b
chr23_+_39695827 0.42 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr7_-_25895189 0.41 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr4_-_2545310 0.41 ENSDART00000150619
ENSDART00000140760
E2F transcription factor 7
chr24_-_21923930 0.41 ENSDART00000131944
transgelin 3b
chr18_+_30028135 0.40 ENSDART00000140825
ENSDART00000145306
ENSDART00000136810
si:ch211-220f16.1
chr7_+_20031202 0.40 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr11_-_45138857 0.40 ENSDART00000166501
calcium activated nucleotidase 1b
chr1_+_53374454 0.40 ENSDART00000038807
uncoupling protein 1
chr13_+_25380432 0.40 ENSDART00000038524
glutathione S-transferase omega 1
chr25_+_5288665 0.40 ENSDART00000169540

chr11_-_1509773 0.40 ENSDART00000050762
phosphatase and actin regulator 3b
chr5_+_19343880 0.40 ENSDART00000148130
acetyl-CoA carboxylase beta
chr17_-_25649079 0.40 ENSDART00000130955
protein phosphatase 1, catalytic subunit, beta isozyme
chr18_-_48550426 0.39 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr23_+_355021 0.39 ENSDART00000190738
adaptor-related protein complex 4, beta 1 subunit
chr3_+_30500968 0.39 ENSDART00000103447
si:dkey-13n23.3
chr19_+_770300 0.39 ENSDART00000062518
glutathione S-transferase rho
chr24_+_23730061 0.39 ENSDART00000080343
protein phosphatase 1, regulatory subunit 42
chr16_-_41004731 0.39 ENSDART00000102591
si:dkey-201i6.2
chr10_-_25860102 0.39 ENSDART00000080789
transient receptor potential cation channel, subfamily C, member 4a
chr10_-_16065185 0.39 ENSDART00000187266
si:dkey-184a18.5
chr25_+_14507567 0.39 ENSDART00000015681
developing brain homeobox 1b
chr3_+_57038033 0.39 ENSDART00000162930
BAH domain and coiled-coil containing 1a
chr5_-_72125551 0.38 ENSDART00000149412
SET and MYND domain containing 1a
chr10_-_26766780 0.38 ENSDART00000146666
MCF.2 cell line derived transforming sequence b
chr20_+_539852 0.38 ENSDART00000185994
dermatan sulfate epimerase
chr12_+_20352400 0.38 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr16_+_16969060 0.38 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
ribosomal protein L18
chr4_+_14900042 0.38 ENSDART00000018261
aldo-keto reductase family 1, member B1 (aldose reductase)
chr12_-_19007834 0.38 ENSDART00000153248
chondroadherin-like b
chr1_+_33668236 0.38 ENSDART00000122316
ENSDART00000102184
ADP-ribosylation factor-like 13b
chr13_+_31402067 0.38 ENSDART00000019202
tudor domain containing 9
chr25_+_31868268 0.38 ENSDART00000022325
poly (ADP-ribose) polymerase family, member 16
chr13_+_4225173 0.38 ENSDART00000058242
ENSDART00000143456
male-enhanced antigen 1
chr22_+_20427170 0.38 ENSDART00000136744
forkhead box Q2
chr16_-_51271962 0.38 ENSDART00000164021
ENSDART00000046420
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr21_+_28445052 0.37 ENSDART00000077871
phosphorylase, glycogen, muscle A
chr10_+_42358426 0.37 ENSDART00000025691
drebrin-like a
chr23_+_31913292 0.37 ENSDART00000136910
armadillo repeat containing 1, like
chr3_+_13624815 0.37 ENSDART00000161451
peptidoglycan recognition protein 6
chr2_+_26288301 0.37 ENSDART00000017668
polypyrimidine tract binding protein 1a
chr11_+_30057762 0.37 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr16_-_36093776 0.37 ENSDART00000159134
organic solute carrier partner 1
chr11_+_26604224 0.37 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynein, light chain, roadblock-type 1
chr25_-_3469576 0.37 ENSDART00000186738
HMG-box transcription factor 1
chr20_-_46362606 0.37 ENSDART00000153087
BCL2 modifying factor 2
chr10_+_6884123 0.37 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr20_+_4060839 0.36 ENSDART00000178565
tripartite motif containing 67
chr7_+_19562045 0.36 ENSDART00000077545
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7

Network of associatons between targets according to the STRING database.

First level regulatory network of meox2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030238 male sex determination(GO:0030238)
0.2 0.7 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.2 1.0 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 1.4 GO:0001659 temperature homeostasis(GO:0001659)
0.2 0.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.2 1.7 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.5 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.5 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 0.5 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.2 0.5 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.7 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 2.5 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.1 0.4 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.4 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.1 0.4 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.1 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.4 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.1 0.3 GO:0010657 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.4 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.9 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.3 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.7 GO:0007141 male meiosis I(GO:0007141)
0.1 1.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.3 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.1 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.4 GO:0010872 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
0.1 0.4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.4 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.6 GO:0035627 ceramide transport(GO:0035627)
0.1 0.4 GO:0032877 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 0.2 GO:0097435 fibril organization(GO:0097435)
0.1 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.4 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) microglia development(GO:0014005) regulation of cellular amine metabolic process(GO:0033238)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 1.0 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 1.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.3 GO:0010159 specification of organ position(GO:0010159)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.3 GO:0015677 copper ion import(GO:0015677)
0.1 0.2 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.3 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.2 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.4 GO:0043584 nose development(GO:0043584)
0.1 1.1 GO:0008406 gonad development(GO:0008406)
0.1 0.6 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.2 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.2 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.8 GO:0046113 pyrimidine nucleobase catabolic process(GO:0006208) nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.0 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.3 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.2 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.3 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.2 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.3 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.2 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.2 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.1 GO:0060155 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.3 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 1.3 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.7 GO:0006094 gluconeogenesis(GO:0006094)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.6 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.5 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.1 GO:0043606 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0089700 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.5 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.1 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.3 GO:0051383 kinetochore organization(GO:0051383)
0.0 0.3 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.5 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.0 0.1 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.1 GO:0006562 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) proline catabolic process(GO:0006562) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.0 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.4 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671) hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.0 0.1 GO:0032732 interleukin-1 production(GO:0032612) regulation of interleukin-1 production(GO:0032652) positive regulation of interleukin-1 production(GO:0032732)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011) anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.2 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.2 GO:1901642 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 4.4 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.4 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.2 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.0 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.8 GO:0030048 actin filament-based movement(GO:0030048)
0.0 1.2 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0007379 somite specification(GO:0001757) segment specification(GO:0007379)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 2.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 1.8 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.6 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0005903 brush border(GO:0005903)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.8 GO:0022626 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.6 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.2 0.7 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.2 1.0 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.7 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.5 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.2 1.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.1 0.7 GO:0043295 glutathione binding(GO:0043295)
0.1 0.7 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.6 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 0.9 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.0 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.5 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.4 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.3 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.3 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.1 0.2 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.5 GO:0008061 chitin binding(GO:0008061)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.6 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0038046 enkephalin receptor activity(GO:0038046)
0.0 0.2 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.8 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0098847 double-stranded telomeric DNA binding(GO:0003691) single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.5 GO:0019239 deaminase activity(GO:0019239)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0048487 beta-tubulin binding(GO:0048487)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 2.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.