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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mixl1+mxtx1+sebox

Z-value: 0.56

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Transcription factors associated with mixl1+mxtx1+sebox

Gene Symbol Gene ID Gene Info
sebox
ENSDARG00000042526 SEBOX homeobox
mixl1
ENSDARG00000069252 Mix paired-like homeobox
mxtx1
ENSDARG00000069382 mix-type homeobox gene 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mixl1dr11_v1_chr20_-_43723860_43723860-0.625.6e-03Click!
seboxdr11_v1_chr5_+_67371650_67371650-0.331.8e-01Click!
mxtx1dr11_v1_chr13_-_21660203_21660203-0.322.0e-01Click!

Activity profile of mixl1+mxtx1+sebox motif

Sorted Z-values of mixl1+mxtx1+sebox motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_23426339 2.13 ENSDART00000004625
zar1
zygote arrest 1
chr1_-_18811517 1.41 ENSDART00000142026
si:dkey-167i21.2
si:dkey-167i21.2
chr2_+_6253246 1.35 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr18_-_40708537 1.01 ENSDART00000077577
si:ch211-132b12.8
si:ch211-132b12.8
chr3_+_28860283 0.96 ENSDART00000077235
alg1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr10_-_21362071 0.94 ENSDART00000125167
avd
avidin
chr8_+_45334255 0.88 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr10_-_21362320 0.88 ENSDART00000189789
avd
avidin
chr16_-_42056137 0.87 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr21_+_25777425 0.87 ENSDART00000021620
cldnd
claudin d
chr22_+_4488454 0.77 ENSDART00000170620
ctxn1
cortexin 1
chr16_-_29387215 0.73 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr24_-_37640705 0.71 ENSDART00000066583
zgc:112496
zgc:112496
chr1_-_55248496 0.71 ENSDART00000098615
nanos3
nanos homolog 3
chr20_-_14114078 0.67 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr22_-_2937503 0.61 ENSDART00000092991
ENSDART00000131110
pigx
phosphatidylinositol glycan anchor biosynthesis, class X
chr20_+_52554352 0.60 ENSDART00000153217
ENSDART00000145230
eef1db
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr17_+_16046132 0.60 ENSDART00000155005
si:ch73-204p21.2
si:ch73-204p21.2
chr12_-_14143344 0.57 ENSDART00000152742
buc2l
bucky ball 2-like
chr10_-_25217347 0.56 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr17_+_16046314 0.55 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr14_-_33481428 0.53 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lamp2
lysosomal-associated membrane protein 2
chr5_-_20491198 0.47 ENSDART00000183051
ENSDART00000144232
ficd
FIC domain containing
chr7_-_51773166 0.46 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr3_-_26244256 0.46 ENSDART00000103741
ppp4ca
protein phosphatase 4, catalytic subunit a
chr4_-_5455506 0.46 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
si:dkey-14d8.22
chr20_-_20931197 0.45 ENSDART00000152726
btbd6b
BTB (POZ) domain containing 6b
chr20_-_20930926 0.43 ENSDART00000123909
btbd6b
BTB (POZ) domain containing 6b
chr17_-_40956035 0.43 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr14_+_34492288 0.43 ENSDART00000144301
wnt8a
wingless-type MMTV integration site family, member 8a
chr16_+_29509133 0.41 ENSDART00000112116
ctss2.1
cathepsin S, ortholog2, tandem duplicate 1
chr11_-_41220794 0.40 ENSDART00000192895
mrps16
mitochondrial ribosomal protein S16
chr21_+_42226113 0.39 ENSDART00000170362
GABRB2 (1 of many)
gamma-aminobutyric acid type A receptor beta2 subunit
chr24_+_40860320 0.39 ENSDART00000161351
gorasp1b
golgi reassembly stacking protein 1b
chr25_-_27621268 0.38 ENSDART00000146205
ENSDART00000073511
hyal6
hyaluronoglucosaminidase 6
chr18_+_19456648 0.37 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr8_+_25034544 0.37 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr19_+_7152966 0.37 ENSDART00000080348
brd2a
bromodomain containing 2a
chr16_-_43344859 0.36 ENSDART00000058680
psma2
proteasome subunit alpha 2
chr20_-_37813863 0.35 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr8_+_36500308 0.35 ENSDART00000098701
slc7a4
solute carrier family 7, member 4
chr14_+_34490445 0.34 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr6_+_50381665 0.34 ENSDART00000141128
cyc1
cytochrome c-1
chr23_+_31913292 0.34 ENSDART00000136910
armc1l
armadillo repeat containing 1, like
chr23_+_31912882 0.34 ENSDART00000140505
armc1l
armadillo repeat containing 1, like
chr11_-_1550709 0.33 ENSDART00000110097
si:ch73-303b9.1
si:ch73-303b9.1
chr20_-_16171297 0.33 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr10_+_43039947 0.32 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr19_+_40069524 0.30 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr16_+_33902006 0.29 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr1_+_35985813 0.29 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr6_+_21001264 0.28 ENSDART00000044519
ENSDART00000151278
cx44.2
connexin 44.2
chr21_+_34088377 0.28 ENSDART00000170070
mtmr1b
myotubularin related protein 1b
chr24_+_12835935 0.28 ENSDART00000114762
nanog
nanog homeobox
chr21_-_11654422 0.27 ENSDART00000081614
ENSDART00000132699
cast
calpastatin
chr17_+_37227936 0.27 ENSDART00000076009
hadhab
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b
chr2_+_50608099 0.27 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr23_-_25135046 0.27 ENSDART00000184844
ENSDART00000103989
idh3g
isocitrate dehydrogenase 3 (NAD+) gamma
chr11_+_33818179 0.27 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr21_+_34088110 0.27 ENSDART00000145123
ENSDART00000029599
ENSDART00000147519
mtmr1b
myotubularin related protein 1b
chr20_-_45062514 0.26 ENSDART00000183529
ENSDART00000182955
klhl29
kelch-like family member 29
chr6_+_40922572 0.26 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eif4enif1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr5_+_37903790 0.25 ENSDART00000162470
tmprss4b
transmembrane protease, serine 4b
chr10_-_32494499 0.25 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr16_+_47207691 0.24 ENSDART00000062507
ica1
islet cell autoantigen 1
chr13_+_2625150 0.24 ENSDART00000164177
plpp4
phospholipid phosphatase 4
chr18_-_19456269 0.24 ENSDART00000060363
rpl4
ribosomal protein L4
chr7_+_28612671 0.24 ENSDART00000019991
slc7a6os
solute carrier family 7, member 6 opposite strand
chr3_+_17537352 0.24 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr22_-_20166660 0.24 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr1_-_43727012 0.24 ENSDART00000181064
bdh2
3-hydroxybutyrate dehydrogenase, type 2
chr25_+_11456696 0.24 ENSDART00000171408
AGBL1
si:ch73-141f14.1
chr24_+_21540842 0.23 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr3_-_16719244 0.23 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr10_-_32494304 0.23 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr24_-_30862168 0.22 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr6_+_50381347 0.21 ENSDART00000055504
cyc1
cytochrome c-1
chr20_-_45060241 0.21 ENSDART00000185227
klhl29
kelch-like family member 29
chr24_+_16547035 0.21 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr8_-_37249813 0.20 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
rbm39b
RNA binding motif protein 39b
chr19_-_5103141 0.20 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr21_-_39177564 0.18 ENSDART00000065143
unc119b
unc-119 homolog b (C. elegans)
chr3_+_32365811 0.18 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr20_-_52902693 0.17 ENSDART00000166115
ENSDART00000161050
ctsbb
cathepsin Bb
chr20_-_52338782 0.17 ENSDART00000109735
ENSDART00000132941
si:ch1073-287p18.1
si:ch1073-287p18.1
chr12_+_20352400 0.16 ENSDART00000066383
hbae5
hemoglobin, alpha embryonic 5
chr20_-_7583486 0.16 ENSDART00000144729
usp24
ubiquitin specific peptidase 24
chr13_+_4225173 0.16 ENSDART00000058242
ENSDART00000143456
mea1
male-enhanced antigen 1
chr15_-_18115540 0.16 ENSDART00000131639
ENSDART00000047902
arcn1b
archain 1b
chr22_+_31207799 0.15 ENSDART00000133267
grip2b
glutamate receptor interacting protein 2b
chr25_+_31276842 0.15 ENSDART00000187238
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr18_-_29896367 0.15 ENSDART00000191303
cmc2
C-x(9)-C motif containing 2
chr6_-_12172424 0.15 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr3_-_31079186 0.15 ENSDART00000145636
ENSDART00000140569
ELOB (1 of many)
elob
elongin B
elongin B
chr23_+_39695827 0.14 ENSDART00000113893
ENSDART00000186679
tmco4
transmembrane and coiled-coil domains 4
chr21_-_23331619 0.13 ENSDART00000007806
zbtb16a
zinc finger and BTB domain containing 16a
chr24_-_24724233 0.13 ENSDART00000127044
ENSDART00000012399
armc1
armadillo repeat containing 1
chr24_+_32668675 0.13 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
si:ch211-282b22.1
chr2_-_3678029 0.13 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr19_-_32710922 0.13 ENSDART00000004034
hpca
hippocalcin
chr17_+_43032529 0.13 ENSDART00000055611
ENSDART00000154863
isca2
iron-sulfur cluster assembly 2
chr21_-_32060993 0.13 ENSDART00000131651
si:ch211-160j14.2
si:ch211-160j14.2
chr14_-_22113600 0.13 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr8_-_37249991 0.12 ENSDART00000189275
ENSDART00000178556
rbm39b
RNA binding motif protein 39b
chr15_-_16177603 0.12 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr21_+_15592426 0.12 ENSDART00000138207
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr5_+_52167986 0.12 ENSDART00000162256
ENSDART00000073626
slc14a2
solute carrier family 14 (urea transporter), member 2
chr22_-_10586191 0.12 ENSDART00000148418
si:dkey-42i9.16
si:dkey-42i9.16
chr12_-_30359498 0.11 ENSDART00000152981
ENSDART00000189988
tdrd1
tudor domain containing 1
chr5_+_36611128 0.10 ENSDART00000097684
nova1
neuro-oncological ventral antigen 1
chr19_+_15441022 0.10 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr1_-_26444075 0.10 ENSDART00000125690
ints12
integrator complex subunit 12
chr3_-_29899172 0.09 ENSDART00000140518
ENSDART00000020311
rpl27
ribosomal protein L27
chr16_+_42471455 0.09 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr13_+_1132261 0.09 ENSDART00000146049
wdr92
WD repeat domain 92
chr15_-_2519640 0.09 ENSDART00000047013
srprb
signal recognition particle receptor, B subunit
chr9_-_31278048 0.09 ENSDART00000022204
zic5
zic family member 5 (odd-paired homolog, Drosophila)
chr13_-_24311628 0.08 ENSDART00000004420
rab4a
RAB4a, member RAS oncogene family
chr11_+_26604224 0.08 ENSDART00000030453
ENSDART00000168895
ENSDART00000159505
dynlrb1
dynein, light chain, roadblock-type 1
chr5_-_37871526 0.08 ENSDART00000136450
arhgap35b
Rho GTPase activating protein 35b
chr9_-_746317 0.07 ENSDART00000129632
ENSDART00000130720
usp37
ubiquitin specific peptidase 37
chr17_-_16422654 0.07 ENSDART00000150149
tdp1
tyrosyl-DNA phosphodiesterase 1
chr17_-_31639845 0.07 ENSDART00000154196
znf839
zinc finger protein 839
chr17_+_8799451 0.06 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr8_+_11425048 0.06 ENSDART00000018739
tjp2b
tight junction protein 2b (zona occludens 2)
chr21_-_25801956 0.06 ENSDART00000101219
mettl27
methyltransferase like 27
chr6_-_3982783 0.06 ENSDART00000171944
slc25a12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr1_+_135903 0.05 ENSDART00000124837
f10
coagulation factor X
chr14_+_22113331 0.05 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr4_+_3980247 0.05 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr2_+_41526904 0.05 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr23_-_17003533 0.05 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr16_+_5774977 0.04 ENSDART00000134202
ccka
cholecystokinin a
chr21_-_5205617 0.04 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr3_-_50443607 0.04 ENSDART00000074036
rcvrna
recoverin a
chr8_+_37527575 0.04 ENSDART00000147239
or135-1
odorant receptor, family H, subfamily 135, member 1
chr11_+_12052791 0.04 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr3_+_18398876 0.04 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr13_-_12602920 0.04 ENSDART00000102311
lrit3b
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3b
chr17_+_23298928 0.04 ENSDART00000153652
zgc:165461
zgc:165461
chr20_+_19238382 0.04 ENSDART00000136757
fndc4a
fibronectin type III domain containing 4a
chr15_+_31344472 0.04 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
or107-1
odorant receptor, family D, subfamily 107, member 1
chr22_+_19552987 0.04 ENSDART00000105315
hsd11b1la
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr22_-_19552796 0.04 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
si:dkey-78l4.14
chr9_-_19161982 0.03 ENSDART00000081878
pou1f1
POU class 1 homeobox 1
chr1_+_21731382 0.03 ENSDART00000054395
pax5
paired box 5
chr14_+_36521005 0.03 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr22_-_14739491 0.03 ENSDART00000133385
lrp1ba
low density lipoprotein receptor-related protein 1Ba
chr12_+_10631266 0.03 ENSDART00000161455
csf3a
colony stimulating factor 3 (granulocyte) a
chr14_+_45406299 0.03 ENSDART00000173142
ENSDART00000112377
map1lc3cl
microtubule-associated protein 1 light chain 3 gamma, like
chr1_+_21937201 0.03 ENSDART00000087729
kdm4c
lysine (K)-specific demethylase 4C
chr4_-_71912457 0.03 ENSDART00000179685
si:dkey-92c21.1
si:dkey-92c21.1
chr23_+_26003187 0.02 ENSDART00000147271
wisp2
WNT1 inducible signaling pathway protein 2
chr18_+_20560442 0.02 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr21_+_44857293 0.02 ENSDART00000134365
ENSDART00000168217
ENSDART00000065083
fstl4
follistatin-like 4
chr13_+_38430466 0.02 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr1_+_56873359 0.02 ENSDART00000152713
si:ch211-152f2.2
si:ch211-152f2.2
chr7_+_56098590 0.02 ENSDART00000098453
cdh15
cadherin 15, type 1, M-cadherin (myotubule)
chr13_-_31017960 0.02 ENSDART00000145287
wdfy4
WDFY family member 4
chr11_+_29770966 0.02 ENSDART00000088624
ENSDART00000124471
rpgrb
retinitis pigmentosa GTPase regulator b
chr19_-_30524952 0.02 ENSDART00000103506
hpcal4
hippocalcin like 4
chr15_+_857148 0.02 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr10_+_40660772 0.02 ENSDART00000148007
taar19l
trace amine associated receptor 19l
chr4_+_31405646 0.02 ENSDART00000128732
si:rp71-5o12.3
si:rp71-5o12.3
chr5_-_50640171 0.01 ENSDART00000183353
mctp1a
multiple C2 domains, transmembrane 1a
chr5_-_14326959 0.01 ENSDART00000137355
tet3
tet methylcytosine dioxygenase 3
chr1_+_8694196 0.01 ENSDART00000025604
zgc:77849
zgc:77849
chr25_+_3549584 0.01 ENSDART00000165913
ccdc77
coiled-coil domain containing 77
chr19_+_30884706 0.01 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr6_-_54826061 0.01 ENSDART00000149982
tnni1b
troponin I type 1b (skeletal, slow)
chr18_+_507835 0.01 ENSDART00000189701
nedd4a
neural precursor cell expressed, developmentally down-regulated 4a
chr2_+_20332044 0.01 ENSDART00000112131
plppr4a
phospholipid phosphatase related 4a
chr16_-_29458806 0.01 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr8_-_25033681 0.01 ENSDART00000003493
nfyal
nuclear transcription factor Y, alpha, like
chr4_-_49582108 0.00 ENSDART00000154999
si:dkey-159n16.2
si:dkey-159n16.2
chr19_-_20113696 0.00 ENSDART00000188813
npy
neuropeptide Y

Network of associatons between targets according to the STRING database.

First level regulatory network of mixl1+mxtx1+sebox

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.5 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.2 GO:0042755 eating behavior(GO:0042755)
0.1 0.2 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.2 GO:0051645 Golgi localization(GO:0051645)
0.0 0.3 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.5 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.2 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.2 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 2.3 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.3 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.1 GO:0032481 positive regulation of type I interferon production(GO:0032481)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0097189 apoptotic body(GO:0097189)
0.2 0.5 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0030667 secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0009374 biotin binding(GO:0009374)
0.1 2.2 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.5 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.9 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.7 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions