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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mnx1+mnx2a+mnx2b

Z-value: 0.76

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Transcription factors associated with mnx1+mnx2a+mnx2b

Gene Symbol Gene ID Gene Info
mnx2b
ENSDARG00000030350 motor neuron and pancreas homeobox 2b
mnx1
ENSDARG00000035984 motor neuron and pancreas homeobox 1
mnx2a
ENSDARG00000042106 motor neuron and pancreas homeobox 2a
mnx1
ENSDARG00000109419 motor neuron and pancreas homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mnx1dr11_v1_chr7_+_40638210_40638210-0.736.5e-04Click!
mnx2adr11_v1_chr9_+_7724152_7724152-0.561.7e-02Click!
mnx2bdr11_v1_chr1_-_5455498_5455502-0.465.6e-02Click!

Activity profile of mnx1+mnx2a+mnx2b motif

Sorted Z-values of mnx1+mnx2a+mnx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_18130300 2.49 ENSDART00000169146
zgc:175135
zgc:175135
chr11_+_18157260 2.29 ENSDART00000144659
zgc:173545
zgc:173545
chr10_-_8046764 2.16 ENSDART00000099031
zgc:136254
zgc:136254
chr11_-_6452444 1.98 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
larp6b
La ribonucleoprotein domain family, member 6b
chr8_+_45334255 1.88 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr10_-_8060573 1.74 ENSDART00000147104
ENSDART00000099030
si:ch211-251f6.6
si:ch211-251f6.6
chr10_-_8053385 1.71 ENSDART00000142714
si:ch211-251f6.7
si:ch211-251f6.7
chr10_-_21362071 1.68 ENSDART00000125167
avd
avidin
chr20_-_23426339 1.68 ENSDART00000004625
zar1
zygote arrest 1
chr16_-_29387215 1.64 ENSDART00000148787
s100a1
S100 calcium binding protein A1
chr10_-_21362320 1.58 ENSDART00000189789
avd
avidin
chr10_-_25217347 1.39 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr11_-_44801968 1.11 ENSDART00000161846
map1lc3c
microtubule-associated protein 1 light chain 3 gamma
chr12_+_23912074 1.02 ENSDART00000152864
svila
supervillin a
chr17_-_40956035 1.01 ENSDART00000124715
si:dkey-16j16.4
si:dkey-16j16.4
chr16_+_39159752 0.86 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr16_-_42056137 0.81 ENSDART00000102798
zp3d.2
zona pellucida glycoprotein 3d tandem duplicate 2
chr19_+_42432625 0.81 ENSDART00000076938
pogza
pogo transposable element derived with ZNF domain a
chr3_-_27647845 0.81 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr17_+_16046314 0.80 ENSDART00000154554
ENSDART00000154338
ENSDART00000155336
si:ch73-204p21.2
si:ch73-204p21.2
chr13_-_8692860 0.76 ENSDART00000058107
mcfd2
multiple coagulation factor deficiency 2
chr22_-_2937503 0.76 ENSDART00000092991
ENSDART00000131110
pigx
phosphatidylinositol glycan anchor biosynthesis, class X
chr17_+_16090436 0.74 ENSDART00000136059
ENSDART00000138734
znf395a
zinc finger protein 395a
chr21_+_1647990 0.72 ENSDART00000148540
fech
ferrochelatase
chr14_+_34490445 0.67 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr20_-_45060241 0.67 ENSDART00000185227
klhl29
kelch-like family member 29
chr19_-_44065581 0.64 ENSDART00000006338
mterf3
mitochondrial transcription termination factor 3
chr13_+_21768447 0.60 ENSDART00000100941
chchd1
coiled-coil-helix-coiled-coil-helix domain containing 1
chr16_+_35916371 0.59 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr5_+_44805269 0.59 ENSDART00000136965
ctsla
cathepsin La
chr10_+_43039947 0.58 ENSDART00000193434
atg10
ATG10 autophagy related 10 homolog (S. cerevisiae)
chr14_-_16151055 0.58 ENSDART00000162431
ptcd3
pentatricopeptide repeat domain 3
chr12_+_22580579 0.56 ENSDART00000171725
ENSDART00000192290
capgb
capping protein (actin filament), gelsolin-like b
chr20_-_37813863 0.55 ENSDART00000147529
batf3
basic leucine zipper transcription factor, ATF-like 3
chr3_+_27798094 0.55 ENSDART00000075100
ENSDART00000151437
carhsp1
calcium regulated heat stable protein 1
chr14_+_16151368 0.54 ENSDART00000160973
polr1a
polymerase (RNA) I polypeptide A
chr5_-_25733745 0.53 ENSDART00000051566
zgc:101016
zgc:101016
chr6_-_7776612 0.52 ENSDART00000190269
myh9a
myosin, heavy chain 9a, non-muscle
chr9_+_50001746 0.52 ENSDART00000058892
slc38a11
solute carrier family 38, member 11
chr12_+_45238292 0.52 ENSDART00000057983
mrpl38
mitochondrial ribosomal protein L38
chr25_-_4313699 0.51 ENSDART00000154038
syt7a
synaptotagmin VIIa
chr24_-_35561672 0.51 ENSDART00000058564
mcm4
minichromosome maintenance complex component 4
chr14_+_35405518 0.50 ENSDART00000171565
zbtb3
zinc finger and BTB domain containing 3
chr3_-_16719244 0.48 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr19_+_40069524 0.48 ENSDART00000151365
ENSDART00000140926
zmym4
zinc finger, MYM-type 4
chr8_+_2487250 0.47 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
chr14_+_16151636 0.46 ENSDART00000159352
polr1a
polymerase (RNA) I polypeptide A
chr1_+_35985813 0.43 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
zgc:152968
chr5_+_25733774 0.43 ENSDART00000137088
ENSDART00000098467
abhd17b
abhydrolase domain containing 17B
chr1_-_54063520 0.43 ENSDART00000171722
smdt1b
single-pass membrane protein with aspartate-rich tail 1b
chr17_+_14965570 0.43 ENSDART00000066604
gpr137c
G protein-coupled receptor 137c
chr11_-_25257045 0.42 ENSDART00000130477
snai1a
snail family zinc finger 1a
chr17_+_28103675 0.41 ENSDART00000188078
zgc:91908
zgc:91908
chr13_+_38817871 0.41 ENSDART00000187708
col19a1
collagen, type XIX, alpha 1
chr2_+_37227011 0.39 ENSDART00000126587
ENSDART00000084958
samd7
sterile alpha motif domain containing 7
chr8_+_25034544 0.39 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr4_-_16833518 0.39 ENSDART00000179867
ldhba
lactate dehydrogenase Ba
chr2_-_38363017 0.38 ENSDART00000088026
prmt5
protein arginine methyltransferase 5
chr13_-_25719628 0.37 ENSDART00000135383
si:dkey-192p21.6
si:dkey-192p21.6
chr20_-_34028967 0.36 ENSDART00000153408
ENSDART00000033817
scyl3
SCY1-like, kinase-like 3
chr21_-_11654422 0.36 ENSDART00000081614
ENSDART00000132699
cast
calpastatin
chr14_+_35428152 0.36 ENSDART00000172597
sytl4
synaptotagmin-like 4
chr16_-_55028740 0.35 ENSDART00000156368
ENSDART00000161704
zgc:114181
zgc:114181
chr13_-_36034582 0.35 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr24_+_21540842 0.34 ENSDART00000091529
wasf3b
WAS protein family, member 3b
chr2_+_41526904 0.33 ENSDART00000127520
acvr1l
activin A receptor, type 1 like
chr17_+_31221761 0.33 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr24_-_30862168 0.32 ENSDART00000168540
ptbp2a
polypyrimidine tract binding protein 2a
chr22_-_20166660 0.32 ENSDART00000085913
ENSDART00000188241
btbd2a
BTB (POZ) domain containing 2a
chr20_-_7128612 0.31 ENSDART00000146755
ENSDART00000036871
si:ch211-121a2.4
si:ch211-121a2.4
chr17_+_30369396 0.31 ENSDART00000076611
greb1
growth regulation by estrogen in breast cancer 1
chr6_+_14301214 0.30 ENSDART00000129491
tmem182b
transmembrane protein 182b
chr16_+_33902006 0.30 ENSDART00000161807
ENSDART00000159474
gnl2
guanine nucleotide binding protein-like 2 (nucleolar)
chr1_-_32111882 0.29 ENSDART00000112639
ENSDART00000101958
pnpla4
patatin-like phospholipase domain containing 4
chr19_+_15441022 0.29 ENSDART00000098970
ENSDART00000140276
lin28a
lin-28 homolog A (C. elegans)
chr12_-_13549538 0.28 ENSDART00000133895
ghdc
GH3 domain containing
chr17_+_43867889 0.27 ENSDART00000132673
ENSDART00000167214
zgc:66313
zgc:66313
chr18_+_15644559 0.27 ENSDART00000061794
nr1h4
nuclear receptor subfamily 1, group H, member 4
chr7_-_46777876 0.26 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr20_-_16171297 0.25 ENSDART00000012476
coa7
cytochrome c oxidase assembly factor 7
chr2_+_50608099 0.24 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr18_+_19456648 0.24 ENSDART00000079695
zwilch
zwilch kinetochore protein
chr15_+_31344472 0.24 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
or107-1
odorant receptor, family D, subfamily 107, member 1
chr10_+_29850330 0.24 ENSDART00000168898
hspa8
heat shock protein 8
chr17_-_21162821 0.24 ENSDART00000157283
abhd12
abhydrolase domain containing 12
chr21_-_14966718 0.24 ENSDART00000151200
mmp17a
matrix metallopeptidase 17a
chr7_+_69019851 0.23 ENSDART00000162891
CABZ01057488.1

chr10_-_32494499 0.23 ENSDART00000129395
uvrag
UV radiation resistance associated gene
chr10_+_42521943 0.23 ENSDART00000010420
ENSDART00000075303
actr1
ARP1 actin related protein 1, centractin
chr8_-_25034411 0.23 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr5_+_20147830 0.22 ENSDART00000098727
svopa
SV2 related protein a
chr3_+_32365811 0.22 ENSDART00000155967
ap2a1
adaptor-related protein complex 2, alpha 1 subunit
chr10_-_32494304 0.21 ENSDART00000028161
uvrag
UV radiation resistance associated gene
chr14_+_22113331 0.21 ENSDART00000109759
tmx2a
thioredoxin-related transmembrane protein 2a
chr19_+_5480327 0.21 ENSDART00000148794
jupb
junction plakoglobin b
chr9_-_50001606 0.21 ENSDART00000161648
ENSDART00000168514
scn1a
sodium channel, voltage-gated, type I, alpha
chr18_-_14677936 0.20 ENSDART00000111995
si:dkey-238o13.4
si:dkey-238o13.4
chr20_+_27712714 0.20 ENSDART00000008306
zbtb1
zinc finger and BTB domain containing 1
chr8_+_2487883 0.20 ENSDART00000101841
dynll1
dynein, light chain, LC8-type 1
chr22_-_7129631 0.19 ENSDART00000171359
asic1b
acid-sensing (proton-gated) ion channel 1b
chr1_-_44812014 0.19 ENSDART00000139044
si:dkey-9i23.8
si:dkey-9i23.8
chr12_+_32199651 0.19 ENSDART00000153027
si:ch211-277e21.1
si:ch211-277e21.1
chr15_-_26931541 0.19 ENSDART00000027563
ccdc9
coiled-coil domain containing 9
chr11_-_39118882 0.19 ENSDART00000113185
ENSDART00000156526
ap5b1
adaptor-related protein complex 5, beta 1 subunit
chr15_-_17138640 0.18 ENSDART00000080777
mrpl28
mitochondrial ribosomal protein L28
chr22_-_10440688 0.18 ENSDART00000111962
nol8
nucleolar protein 8
chr14_-_22113600 0.18 ENSDART00000113752
si:dkey-6i22.5
si:dkey-6i22.5
chr11_+_33818179 0.17 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr22_+_9027884 0.17 ENSDART00000171839
si:ch211-213a13.2
si:ch211-213a13.2
chr25_-_20258508 0.15 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dnm1l
dynamin 1-like
chr1_+_11977426 0.15 ENSDART00000103399
tspan5b
tetraspanin 5b
chr17_-_37395460 0.15 ENSDART00000148160
ENSDART00000075975
crip1
cysteine-rich protein 1
chr1_-_9123465 0.15 ENSDART00000081337
ndufab1a
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1a
chr3_-_32873641 0.13 ENSDART00000075277
zgc:113090
zgc:113090
chr17_-_44249720 0.13 ENSDART00000156648
otx2b
orthodenticle homeobox 2b
chr10_+_11282883 0.13 ENSDART00000135355
si:ch211-126i22.5
si:ch211-126i22.5
chr18_-_19456269 0.13 ENSDART00000060363
rpl4
ribosomal protein L4
chr13_+_38430466 0.13 ENSDART00000132691
adgrb3
adhesion G protein-coupled receptor B3
chr20_+_25879826 0.12 ENSDART00000018519
zgc:153896
zgc:153896
chr19_+_15440841 0.12 ENSDART00000182329
lin28a
lin-28 homolog A (C. elegans)
chr25_+_13620555 0.12 ENSDART00000163642
si:ch211-172l8.4
si:ch211-172l8.4
chr4_-_15103646 0.12 ENSDART00000138183
ENSDART00000181044
nrf1
nuclear respiratory factor 1
chr16_+_42471455 0.11 ENSDART00000166640
si:ch211-215k15.5
si:ch211-215k15.5
chr20_-_43663494 0.11 ENSDART00000144564
BX470188.1

chr22_+_16308806 0.11 ENSDART00000162685
lrrc39
leucine rich repeat containing 39
chr2_-_28671139 0.11 ENSDART00000165272
ENSDART00000164657
dhcr7
7-dehydrocholesterol reductase
chr8_-_30979494 0.11 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr22_-_36836085 0.10 ENSDART00000131451
cart1
cocaine- and amphetamine-regulated transcript 1
chr7_-_23768234 0.10 ENSDART00000173981
si:ch211-200p22.4
si:ch211-200p22.4
chr6_-_3998199 0.10 ENSDART00000059212
unc50
unc-50 homolog (C. elegans)
chr19_+_1835940 0.09 ENSDART00000167372
ptk2aa
protein tyrosine kinase 2aa
chr4_+_3980247 0.09 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr15_-_16177603 0.09 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr19_-_5103141 0.09 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr13_-_31017960 0.09 ENSDART00000145287
wdfy4
WDFY family member 4
chr15_-_4528326 0.08 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
chr10_-_28028998 0.08 ENSDART00000023545
ENSDART00000143487
ints2
integrator complex subunit 2
chr17_+_23298928 0.08 ENSDART00000153652
zgc:165461
zgc:165461
chr18_+_9637744 0.08 ENSDART00000190171
pclob
piccolo presynaptic cytomatrix protein b
chr19_+_30884706 0.08 ENSDART00000052126
yars
tyrosyl-tRNA synthetase
chr9_-_14273652 0.08 ENSDART00000135458
abcb6b
ATP-binding cassette, sub-family B (MDR/TAP), member 6b
chr12_+_30723778 0.08 ENSDART00000153291
slc35f3a
solute carrier family 35, member F3a
chr4_-_16334362 0.08 ENSDART00000101461
epyc
epiphycan
chr15_+_6109861 0.07 ENSDART00000185154
PCP4 (1 of many)
Purkinje cell protein 4
chr1_-_22512063 0.07 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr7_+_39418869 0.07 ENSDART00000169195
CT030188.1

chr10_-_33297864 0.07 ENSDART00000163360
PRDM15
PR/SET domain 15
chr7_-_44957503 0.07 ENSDART00000165077
cdh16
cadherin 16, KSP-cadherin
chr24_-_29963858 0.07 ENSDART00000183442
CR352310.1

chr20_-_19511700 0.07 ENSDART00000040191
snx17
sorting nexin 17
chr19_-_32641725 0.07 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr23_+_28809002 0.06 ENSDART00000134121
ENSDART00000183661
pex14
peroxisomal biogenesis factor 14
chr5_+_32847238 0.06 ENSDART00000144364
si:ch211-208h16.4
si:ch211-208h16.4
chr6_-_51386656 0.06 ENSDART00000154732
ENSDART00000177990
ENSDART00000184928
ENSDART00000180197
ptprt
protein tyrosine phosphatase, receptor type, t
chr23_-_31512496 0.06 ENSDART00000158755
ENSDART00000143425
eya4
EYA transcriptional coactivator and phosphatase 4
chr15_+_857148 0.06 ENSDART00000156949
si:dkey-7i4.13
si:dkey-7i4.13
chr7_-_31321027 0.06 ENSDART00000186878
CR356242.1

chr16_+_26777473 0.06 ENSDART00000188870
cdh17
cadherin 17, LI cadherin (liver-intestine)
chr10_+_33744098 0.06 ENSDART00000147775
rxfp2a
relaxin/insulin-like family peptide receptor 2a
chr15_+_42933236 0.06 ENSDART00000167763
slc8a2b
solute carrier family 8 (sodium/calcium exchanger), member 2b
chr9_+_22485343 0.06 ENSDART00000146028
dgkg
diacylglycerol kinase, gamma
chr20_+_31076488 0.05 ENSDART00000136255
ENSDART00000008840
otofa
otoferlin a
chr23_+_16638639 0.05 ENSDART00000143545
snphb
syntaphilin b
chr14_+_36521005 0.05 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr11_-_25539323 0.05 ENSDART00000155785
si:dkey-245f22.3
si:dkey-245f22.3
chr25_+_28282274 0.05 ENSDART00000164502
aass
aminoadipate-semialdehyde synthase
chr8_-_12867128 0.05 ENSDART00000142201
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr22_+_30543437 0.05 ENSDART00000137983
si:dkey-103k4.1
si:dkey-103k4.1
chr21_-_42007213 0.05 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gabrg2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr17_+_49500820 0.05 ENSDART00000170306
AREL1
apoptosis resistant E3 ubiquitin protein ligase 1
chr6_-_40029423 0.05 ENSDART00000103230
pfkfb4b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr22_-_10397600 0.04 ENSDART00000181964
ENSDART00000142886
nisch
nischarin
chr22_-_24818066 0.04 ENSDART00000143443
vtg6
vitellogenin 6
chr21_+_28478663 0.04 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr8_+_21229718 0.04 ENSDART00000100222
cry1ba
cryptochrome circadian clock 1ba
chr7_+_17229980 0.04 ENSDART00000184910
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr10_+_40660772 0.04 ENSDART00000148007
taar19l
trace amine associated receptor 19l
chr19_-_30524952 0.04 ENSDART00000103506
hpcal4
hippocalcin like 4
chr12_+_30367371 0.03 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr18_-_33979422 0.03 ENSDART00000136535
ENSDART00000167698
si:ch211-203b20.7
si:ch211-203b20.7
chr8_-_12867434 0.03 ENSDART00000081657
slc2a6
solute carrier family 2 (facilitated glucose transporter), member 6
chr3_-_26806032 0.03 ENSDART00000143710
pigq
phosphatidylinositol glycan anchor biosynthesis, class Q
chr21_+_5580948 0.03 ENSDART00000160373
ly6m7
lymphocyte antigen 6 family member M7
chr9_-_38021889 0.03 ENSDART00000183482
ENSDART00000124333
adcy5
adenylate cyclase 5
chr18_+_20560442 0.03 ENSDART00000151990
wee2
WEE1 homolog 2 (S. pombe)
chr12_+_5081759 0.03 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr11_+_12052791 0.02 ENSDART00000158479
si:ch211-156l18.8
si:ch211-156l18.8
chr8_-_8446668 0.02 ENSDART00000132700
cdk16
cyclin-dependent kinase 16
chr14_+_25817628 0.02 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr6_+_24398907 0.02 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr11_-_12998400 0.02 ENSDART00000018614
chrna4b
cholinergic receptor, nicotinic, alpha 4b
chr4_+_31405646 0.02 ENSDART00000128732
si:rp71-5o12.3
si:rp71-5o12.3
chr3_+_45368973 0.02 ENSDART00000187282
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr6_-_11780070 0.02 ENSDART00000151195
march7
membrane-associated ring finger (C3HC4) 7
chr10_+_40568735 0.01 ENSDART00000136468
ENSDART00000182841
taar18i
trace amine associated receptor 18i
chr12_+_30367079 0.01 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr22_-_392224 0.01 ENSDART00000124720
CABZ01072989.1

chr8_-_30204650 0.01 ENSDART00000133209
zgc:162939
zgc:162939
chr1_+_33969015 0.01 ENSDART00000042984
ENSDART00000146530
epha6
eph receptor A6
chr23_+_25354856 0.01 ENSDART00000109023
ENSDART00000147440
fmnl3
formin-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of mnx1+mnx2a+mnx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.9 GO:0060074 synapse maturation(GO:0060074)
0.2 0.6 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.5 GO:0072104 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.4 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.3 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 1.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.5 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 1.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 1.6 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.8 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 2.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 1.2 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.4 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.8 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.4 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.2 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0070206 protein trimerization(GO:0070206)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 2.4 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0033512 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.3 GO:0046461 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.0 1.6 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 1.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.1 GO:0032096 adult feeding behavior(GO:0008343) negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.3 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:1901099 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0097189 apoptotic body(GO:0097189)
0.2 6.7 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.3 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.3 GO:0009374 biotin binding(GO:0009374)
0.2 0.6 GO:0019777 Atg12 transferase activity(GO:0019777)
0.2 5.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 2.3 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.1 1.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.3 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 1.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0032052 bile acid binding(GO:0032052)
0.0 0.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.3 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.7 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters