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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for msc

Z-value: 0.48

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Transcription factors associated with msc

Gene Symbol Gene ID Gene Info
msc
ENSDARG00000110016 musculin (activated B-cell factor-1)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mscdr11_v1_chr24_+_13735616_13735616-0.503.5e-02Click!

Activity profile of msc motif

Sorted Z-values of msc motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_11756040 0.66 ENSDART00000105808
krt97
keratin 97
chr3_-_29962345 0.62 ENSDART00000136819
bcat2
branched chain amino-acid transaminase 2, mitochondrial
chr25_-_9013963 0.62 ENSDART00000073912
rag2
recombination activating gene 2
chr25_-_19655820 0.56 ENSDART00000149585
ENSDART00000104353
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr3_+_17910569 0.54 ENSDART00000080946
ttc25
tetratricopeptide repeat domain 25
chr10_-_6867282 0.51 ENSDART00000144001
ENSDART00000109744
ppip5k2
diphosphoinositol pentakisphosphate kinase 2
chr16_-_4610255 0.47 ENSDART00000081852
ENSDART00000123253
ENSDART00000127554
ENSDART00000029485
arnt
aryl hydrocarbon receptor nuclear translocator
chr16_-_28727763 0.41 ENSDART00000149575
dcst1
DC-STAMP domain containing 1
chr18_+_19820008 0.41 ENSDART00000079691
ENSDART00000135049
iqch
IQ motif containing H
chr24_-_35707552 0.41 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr12_-_33659328 0.40 ENSDART00000153457
tmem94
transmembrane protein 94
chr20_-_21672970 0.40 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr5_-_15494164 0.38 ENSDART00000140668
ENSDART00000188076
ENSDART00000085943
taok3a
TAO kinase 3a
chr1_-_39895859 0.38 ENSDART00000135791
ENSDART00000035739
tmem134
transmembrane protein 134
chr6_+_46259950 0.36 ENSDART00000032326
zgc:162324
zgc:162324
chr9_-_40873934 0.36 ENSDART00000066424
pofut2
protein O-fucosyltransferase 2
chr22_+_35472653 0.35 ENSDART00000076424
ENSDART00000187204
tctex1d2
Tctex1 domain containing 2
chr2_-_55779927 0.35 ENSDART00000168579
CABZ01066725.1

chr16_-_13281380 0.35 ENSDART00000103882
grin2db
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr9_+_21795917 0.35 ENSDART00000169069
rev1
REV1, polymerase (DNA directed)
chr7_+_6652967 0.34 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr7_+_19552381 0.33 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr5_-_22019061 0.33 ENSDART00000113066
amer1
APC membrane recruitment protein 1
chr17_+_12075805 0.33 ENSDART00000155329
cnsta
consortin, connexin sorting protein a
chr5_+_25762271 0.32 ENSDART00000181323
tmem2
transmembrane protein 2
chr10_+_22891126 0.32 ENSDART00000057291
arrb2a
arrestin, beta 2a
chr22_+_11775269 0.32 ENSDART00000140272
krt96
keratin 96
chr1_+_27825980 0.30 ENSDART00000160524
pspc1
paraspeckle component 1
chr19_+_7636941 0.30 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr22_+_17214389 0.30 ENSDART00000187083
ENSDART00000159468
ENSDART00000129109
ENSDART00000090107
nrd1b
nardilysin b (N-arginine dibasic convertase)
chr7_-_50367642 0.30 ENSDART00000134941
prc1b
protein regulator of cytokinesis 1b
chr19_-_10214264 0.30 ENSDART00000053300
ENSDART00000148225
znf865
zinc finger protein 865
chr5_-_29152457 0.29 ENSDART00000078469
noxa1
NADPH oxidase activator 1
chr5_-_19400166 0.29 ENSDART00000008994
foxn4
forkhead box N4
chr12_-_33646010 0.29 ENSDART00000111259
tmem94
transmembrane protein 94
chr4_-_75175407 0.29 ENSDART00000180125
CABZ01043953.1

chr8_-_1219815 0.29 ENSDART00000016800
ENSDART00000149969
znf367
zinc finger protein 367
chr4_-_20081621 0.28 ENSDART00000024647
dennd6b
DENN/MADD domain containing 6B
chr7_-_69795488 0.28 ENSDART00000162414
USP53 (1 of many)
ubiquitin specific peptidase 53
chr1_-_14258409 0.28 ENSDART00000079359
pde5aa
phosphodiesterase 5A, cGMP-specific, a
chr20_-_33497128 0.28 ENSDART00000101974
erh
enhancer of rudimentary homolog (Drosophila)
chr1_-_6085750 0.27 ENSDART00000138891
si:ch1073-345a8.1
si:ch1073-345a8.1
chr6_+_23931236 0.27 ENSDART00000166079
gadd45ab
growth arrest and DNA-damage-inducible, alpha, b
chr18_-_14337450 0.27 ENSDART00000061435
hsbp1b
heat shock factor binding protein 1b
chr16_-_21489514 0.26 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
mpp6a
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr2_+_47471943 0.26 ENSDART00000141974
acsl3b
acyl-CoA synthetase long chain family member 3b
chr2_+_47471647 0.26 ENSDART00000184199
acsl3b
acyl-CoA synthetase long chain family member 3b
chr4_-_21466480 0.26 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr7_-_50367326 0.25 ENSDART00000141926
prc1b
protein regulator of cytokinesis 1b
chr10_+_26667475 0.25 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
si:ch73-52f15.5
chr7_+_27059330 0.25 ENSDART00000173919
plekha7b
pleckstrin homology domain containing, family A member 7b
chr17_+_23968214 0.25 ENSDART00000183053
xpo1b
exportin 1 (CRM1 homolog, yeast) b
chr1_-_24349759 0.25 ENSDART00000142740
ENSDART00000177989
lrba
LPS-responsive vesicle trafficking, beach and anchor containing
chr20_+_43691208 0.25 ENSDART00000152976
ENSDART00000045185
lin9
lin-9 DREAM MuvB core complex component
chr8_-_44299247 0.24 ENSDART00000144497
piwil1
piwi-like RNA-mediated gene silencing 1
chr22_+_465269 0.24 ENSDART00000145767
celsr2
cadherin, EGF LAG seven-pass G-type receptor 2
chr15_-_5624361 0.24 ENSDART00000176446
ENSDART00000114410
wdr62
WD repeat domain 62
chr18_-_14337065 0.23 ENSDART00000135703
hsbp1b
heat shock factor binding protein 1b
chr11_-_44999858 0.23 ENSDART00000167759
ENSDART00000126845
ldb1b
LIM-domain binding 1b
chr23_-_21758253 0.23 ENSDART00000046613
vps13d
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr10_+_31809226 0.23 ENSDART00000087898
foxo1b
forkhead box O1 b
chr19_-_6134802 0.23 ENSDART00000140051
cica
capicua transcriptional repressor a
chr10_-_31805923 0.23 ENSDART00000077785
vps26bl
vacuolar protein sorting 26 homolog B, like
chr7_+_17096281 0.23 ENSDART00000035558
htatip2
HIV-1 Tat interactive protein 2
chr14_-_34605804 0.22 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr21_+_27382893 0.22 ENSDART00000005682
actn3a
actinin alpha 3a
chr25_+_36045072 0.22 ENSDART00000126326
rpgrip1l
RPGRIP1-like
chr8_+_8643901 0.22 ENSDART00000142076
ENSDART00000075624
usp11
ubiquitin specific peptidase 11
chr4_-_22335247 0.22 ENSDART00000192781
golgb1
golgin B1
chr19_-_23892243 0.22 ENSDART00000132384
si:dkey-222b8.4
si:dkey-222b8.4
chr1_+_25801648 0.21 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr2_+_1988036 0.21 ENSDART00000155956
ssx2ipa
synovial sarcoma, X breakpoint 2 interacting protein a
chr9_-_28939181 0.21 ENSDART00000101276
ENSDART00000135334
epb41l5
erythrocyte membrane protein band 4.1 like 5
chr14_+_35464994 0.21 ENSDART00000115307
si:ch211-203d1.3
si:ch211-203d1.3
chr18_-_7948188 0.20 ENSDART00000091805
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr8_-_11229523 0.20 ENSDART00000002164
unc45b
unc-45 myosin chaperone B
chr7_-_18470963 0.20 ENSDART00000173929
ENSDART00000173638
znf16l
zinc finger protein 16 like
chr16_+_28728347 0.20 ENSDART00000149240
si:dkey-24i24.3
si:dkey-24i24.3
chr16_+_26706519 0.19 ENSDART00000142706
virma
vir like m6A methyltransferase associated
chr7_-_24364536 0.19 ENSDART00000064789
txn
thioredoxin
chr7_-_59311165 0.19 ENSDART00000171105
m1ap
meiosis 1 associated protein
chr7_+_49664174 0.19 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr7_+_37742299 0.18 ENSDART00000143300
brd7
bromodomain containing 7
chr6_-_35032792 0.18 ENSDART00000168256
ddr2a
discoidin domain receptor tyrosine kinase 2a
chr22_-_22231720 0.18 ENSDART00000160165
ap3d1
adaptor-related protein complex 3, delta 1 subunit
chr8_+_18615938 0.18 ENSDART00000089161
si:ch211-232d19.4
si:ch211-232d19.4
chr16_+_3004422 0.17 ENSDART00000189969
CABZ01043952.1

chr19_+_29808699 0.17 ENSDART00000051799
ENSDART00000164205
hdac1
histone deacetylase 1
chr16_+_40575742 0.17 ENSDART00000161503
ccne2
cyclin E2
chr17_-_51195651 0.17 ENSDART00000191205
ENSDART00000088185
paplna
papilin a, proteoglycan-like sulfated glycoprotein
chr23_-_18057851 0.17 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr19_+_29808471 0.17 ENSDART00000186428
hdac1
histone deacetylase 1
chr1_-_17650223 0.16 ENSDART00000043484
si:dkey-256e7.5
si:dkey-256e7.5
chr20_-_51831657 0.16 ENSDART00000165076
mia3
melanoma inhibitory activity family, member 3
chr7_+_67381912 0.16 ENSDART00000167564
nfat5b
nuclear factor of activated T cells 5b
chr21_+_5974590 0.16 ENSDART00000098499
dck
deoxycytidine kinase
chr23_-_18057553 0.16 ENSDART00000173102
ENSDART00000058742
zgc:92287
zgc:92287
chr13_-_31452516 0.15 ENSDART00000193268
rtn1a
reticulon 1a
chr14_+_21699129 0.15 ENSDART00000073707
stx3a
syntaxin 3A
chr7_+_38962459 0.15 ENSDART00000173851
dgkza
diacylglycerol kinase, zeta a
chr1_-_55118745 0.15 ENSDART00000133915
sertad2a
SERTA domain containing 2a
chr20_-_37831849 0.15 ENSDART00000188483
ENSDART00000153005
ENSDART00000142364
si:ch211-147d7.5
si:ch211-147d7.5
chr19_-_20446756 0.15 ENSDART00000140711
tbc1d5
TBC1 domain family, member 5
chr8_-_14609284 0.15 ENSDART00000146175
cep350
centrosomal protein 350
chr20_-_51831816 0.14 ENSDART00000060505
mia3
melanoma inhibitory activity family, member 3
chr22_-_21897203 0.14 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr11_-_35171162 0.14 ENSDART00000017393
traip
TRAF-interacting protein
chr15_+_34963316 0.14 ENSDART00000153840
si:ch73-95l15.5
si:ch73-95l15.5
chr9_+_32306862 0.14 ENSDART00000078513
mob4
MOB family member 4, phocein
chr10_+_10738880 0.14 ENSDART00000004181
slc27a4
solute carrier family 27 (fatty acid transporter), member 4
chr16_-_26676685 0.14 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr13_+_7575563 0.14 ENSDART00000146592
gbf1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr18_-_3542435 0.14 ENSDART00000184017
dcun1d5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr10_-_1697037 0.13 ENSDART00000125188
ENSDART00000002985
srsf9
serine/arginine-rich splicing factor 9
chr16_+_28764017 0.13 ENSDART00000122433
trim33l
tripartite motif containing 33, like
chr14_-_34605607 0.13 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr9_+_2020667 0.13 ENSDART00000157818
lnpa
limb and neural patterns a
chr19_-_32150078 0.13 ENSDART00000134934
ENSDART00000186410
ENSDART00000181780
pag1
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr15_+_40188076 0.13 ENSDART00000063779
efhd1
EF-hand domain family, member D1
chr16_+_46401576 0.13 ENSDART00000130264
rpz
rapunzel
chr1_-_20593778 0.13 ENSDART00000124770
ugt8
UDP glycosyltransferase 8
chr23_+_19790962 0.13 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr2_-_51087077 0.13 ENSDART00000167987
ftr67
finTRIM family, member 67
chr14_-_46897067 0.12 ENSDART00000058789
qdpra
quinoid dihydropteridine reductase a
chr11_+_18873113 0.12 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr8_-_44298964 0.12 ENSDART00000098520
fzd10
frizzled class receptor 10
chr2_-_15040345 0.12 ENSDART00000109657
si:dkey-10f21.4
si:dkey-10f21.4
chr4_+_20255160 0.12 ENSDART00000188658
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr7_-_41726657 0.12 ENSDART00000099121
arl8
ADP-ribosylation factor-like 8
chr15_-_32383529 0.12 ENSDART00000028349
c4
complement component 4
chr23_-_32162810 0.11 ENSDART00000155905
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr20_+_23501535 0.11 ENSDART00000177922
ENSDART00000058532
palld
palladin, cytoskeletal associated protein
chr6_-_12722360 0.11 ENSDART00000090174
dock9b
dedicator of cytokinesis 9b
chr20_+_18580176 0.11 ENSDART00000185310
si:dkeyp-72h1.1
si:dkeyp-72h1.1
chr10_-_22803740 0.11 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
pcolcea
procollagen C-endopeptidase enhancer a
chr7_+_20471315 0.11 ENSDART00000173714
si:dkey-19b23.13
si:dkey-19b23.13
chr22_-_10891213 0.11 ENSDART00000145229
arhgef18b
rho/rac guanine nucleotide exchange factor (GEF) 18b
chr24_-_9300160 0.11 ENSDART00000152378
tgif1
TGFB-induced factor homeobox 1
chr7_-_29356084 0.11 ENSDART00000075757
gtf2a2
general transcription factor IIA, 2
chr17_-_19466319 0.11 ENSDART00000170429
dicer1
dicer 1, ribonuclease type III
chr4_+_20263097 0.11 ENSDART00000138820
lrtm2a
leucine-rich repeats and transmembrane domains 2a
chr16_-_42750295 0.11 ENSDART00000176570
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_+_38962207 0.11 ENSDART00000173565
dgkza
diacylglycerol kinase, zeta a
chr4_-_18635005 0.11 ENSDART00000125361
pparaa
peroxisome proliferator-activated receptor alpha a
chr16_+_11151699 0.11 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr5_-_13315726 0.11 ENSDART00000143364
sdf2l1
stromal cell-derived factor 2-like 1
chr14_+_30730749 0.11 ENSDART00000087884
ccdc85b
coiled-coil domain containing 85B
chr13_-_31164749 0.11 ENSDART00000049180
mapk8a
mitogen-activated protein kinase 8a
chr25_-_25619550 0.10 ENSDART00000150400
tbc1d2b
TBC1 domain family, member 2B
chr7_+_10610791 0.10 ENSDART00000166064
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr12_-_31103187 0.10 ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
ENSDART00000122972
ENSDART00000153068
tcf7l2
transcription factor 7 like 2
chr2_+_37480669 0.10 ENSDART00000029801
sppl2
signal peptide peptidase-like 2
chr18_-_5781922 0.10 ENSDART00000128722
RGS9BP
si:ch73-167i17.6
chr24_+_33802528 0.10 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
atg9b
autophagy related 9B
chr2_-_7185460 0.10 ENSDART00000092078
rc3h1b
ring finger and CCCH-type domains 1b
chr20_+_20902549 0.10 ENSDART00000181195
brf1b
BRF1, RNA polymerase III transcription initiation factor b
chr14_+_38656776 0.10 ENSDART00000186197
ENSDART00000185861
ENSDART00000020625
fbxo38
F-box protein 38
chr23_-_27647769 0.10 ENSDART00000059974
wnt10b
wingless-type MMTV integration site family, member 10b
chr23_+_13528550 0.10 ENSDART00000099903
uckl1b
uridine-cytidine kinase 1-like 1b
chr3_+_24537023 0.10 ENSDART00000077702
sp100.1
SP110 nuclear body protein, tandem duplicate 1
chr25_-_36044583 0.10 ENSDART00000073432
rbl2
retinoblastoma-like 2 (p130)
chr6_+_23057311 0.10 ENSDART00000026448
evpla
envoplakin a
chr14_+_21699414 0.10 ENSDART00000169942
stx3a
syntaxin 3A
chr2_+_37245382 0.10 ENSDART00000004626
sec62
SEC62 homolog, preprotein translocation factor
chr5_-_17601759 0.09 ENSDART00000138387
si:ch211-130h14.6
si:ch211-130h14.6
chr17_-_42842129 0.09 ENSDART00000009528
mocs3
molybdenum cofactor synthesis 3
chr7_-_7692992 0.09 ENSDART00000192619
aadat
aminoadipate aminotransferase
chr12_-_10505986 0.09 ENSDART00000152672
zgc:152977
zgc:152977
chr20_+_25645459 0.09 ENSDART00000143555
ENSDART00000036350
aasdh
aminoadipate-semialdehyde dehydrogenase
chr10_+_25355308 0.09 ENSDART00000100415
map3k7cl
map3k7 C-terminal like
chr10_-_24371312 0.09 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr8_+_21376290 0.09 ENSDART00000136765
ela2
elastase 2
chr7_+_44715224 0.09 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr16_-_14353567 0.09 ENSDART00000139859
itga10
integrin, alpha 10
chr23_+_35714574 0.09 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr16_-_13623928 0.09 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr23_+_23658474 0.09 ENSDART00000162838
agrn
agrin
chr5_-_30475011 0.09 ENSDART00000187501
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr20_-_26467307 0.09 ENSDART00000078072
ENSDART00000158213
akap12b
A kinase (PRKA) anchor protein 12b
chr23_-_19831739 0.08 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr23_-_30954738 0.08 ENSDART00000188996
osbpl2a
oxysterol binding protein-like 2a
chr8_+_7033049 0.08 ENSDART00000064172
ENSDART00000134440
gpd1a
glycerol-3-phosphate dehydrogenase 1a
chr13_+_1575276 0.08 ENSDART00000165987
DST
dystonin
chr13_+_24834199 0.08 ENSDART00000101274
zgc:153981
zgc:153981
chr3_+_22935183 0.08 ENSDART00000157378
hdac5
histone deacetylase 5
chr2_-_39015130 0.08 ENSDART00000044331
copb2
coatomer protein complex, subunit beta 2
chr6_-_10912424 0.08 ENSDART00000036456
cycsb
cytochrome c, somatic b
chr3_-_12227359 0.08 ENSDART00000167356
tfap4
transcription factor AP-4 (activating enhancer binding protein 4)
chr18_-_26797723 0.08 ENSDART00000008013
sec11a
SEC11 homolog A, signal peptidase complex subunit
chr13_+_42124566 0.08 ENSDART00000074707
cdc42ep3
CDC42 effector protein (Rho GTPase binding) 3
chr18_+_34861568 0.08 ENSDART00000192825
LO018333.1

chr7_-_7692723 0.08 ENSDART00000183352
aadat
aminoadipate aminotransferase
chr3_-_45245607 0.08 ENSDART00000181003
ENSDART00000193586
usp31
ubiquitin specific peptidase 31
chr1_+_2101541 0.08 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
mbnl2
muscleblind-like splicing regulator 2
chr9_-_53666031 0.08 ENSDART00000126314
pcdh8
protocadherin 8
chr10_-_25069155 0.08 ENSDART00000078226
ENSDART00000181941
mtnr1bb
melatonin receptor 1Bb
chr11_+_31730680 0.07 ENSDART00000145497
diaph3
diaphanous-related formin 3
chr13_+_40815012 0.07 ENSDART00000016960
prkg1a
protein kinase, cGMP-dependent, type Ia
chr18_+_35742838 0.07 ENSDART00000088504
ENSDART00000140386
rasgrp4
RAS guanyl releasing protein 4
chr15_+_32727848 0.07 ENSDART00000161361
postnb
periostin, osteoblast specific factor b

Network of associatons between targets according to the STRING database.

First level regulatory network of msc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.6 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.3 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.3 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.2 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.6 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.2 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.1 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.0 0.2 GO:0021744 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.2 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.2 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.3 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.0 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.0 0.5 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.0 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973)
0.0 0.3 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.5 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.0 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.2 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.0 0.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.0 0.6 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.6 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.5 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.3 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.4 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism