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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for msx1b+msx3

Z-value: 0.71

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Transcription factors associated with msx1b+msx3

Gene Symbol Gene ID Gene Info
msx1b
ENSDARG00000008886 muscle segment homeobox 1b
msx3
ENSDARG00000015674 muscle segment homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx3dr11_v1_chr13_+_24662238_24662238-0.832.2e-05Click!
msx1bdr11_v1_chr1_+_49352900_49352900-0.292.4e-01Click!

Activity profile of msx1b+msx3 motif

Sorted Z-values of msx1b+msx3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_9979342 3.20 ENSDART00000138576
ENSDART00000191206
zgc:171977
zgc:171977
chr12_-_33357655 2.64 ENSDART00000066233
ENSDART00000148165
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr5_-_29512538 2.33 ENSDART00000098364
ehmt1a
euchromatic histone-lysine N-methyltransferase 1a
chr5_+_29794058 2.15 ENSDART00000045410
thy1
Thy-1 cell surface antigen
chr17_-_50071748 2.05 ENSDART00000075188
zgc:113886
zgc:113886
chr2_+_6253246 2.04 ENSDART00000058256
ENSDART00000076700
zp3b
zona pellucida glycoprotein 3b
chr19_-_8768564 1.77 ENSDART00000170416
si:ch73-350k19.1
si:ch73-350k19.1
chr9_-_35633827 1.56 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr14_+_34490445 1.46 ENSDART00000132193
ENSDART00000148044
wnt8a
wingless-type MMTV integration site family, member 8a
chr15_+_46344655 1.44 ENSDART00000155893
si:ch1073-340i21.2
si:ch1073-340i21.2
chr19_-_18127808 1.31 ENSDART00000108627
snx10a
sorting nexin 10a
chr22_-_21150845 1.23 ENSDART00000027345
tmem59l
transmembrane protein 59-like
chr3_-_26191960 1.20 ENSDART00000113843
ypel3
yippee-like 3
chr19_-_18127629 1.18 ENSDART00000187722
snx10a
sorting nexin 10a
chr3_+_32663865 1.08 ENSDART00000190240
si:dkey-16l2.16
si:dkey-16l2.16
chr4_-_77260727 1.05 ENSDART00000075770
zgc:162948
zgc:162948
chr9_-_32343673 1.05 ENSDART00000078499
rftn2
raftlin family member 2
chr5_-_31926906 1.00 ENSDART00000187340
ssh1b
slingshot protein phosphatase 1b
chr16_-_41714988 0.98 ENSDART00000138798
cep85
centrosomal protein 85
chr4_+_4849789 0.98 ENSDART00000130818
ENSDART00000127751
ptprz1b
protein tyrosine phosphatase, receptor-type, Z polypeptide 1b
chr8_-_15129573 0.97 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr17_-_6618574 0.95 ENSDART00000184486
si:ch211-189e2.3
si:ch211-189e2.3
chr6_-_9695294 0.93 ENSDART00000162728
nop58
NOP58 ribonucleoprotein homolog (yeast)
chr10_+_17235370 0.87 ENSDART00000038780
sppl3
signal peptide peptidase 3
chr20_-_51831816 0.85 ENSDART00000060505
mia3
melanoma inhibitory activity family, member 3
chr5_+_872299 0.83 ENSDART00000130042
fubp3
far upstream element (FUSE) binding protein 3
chr11_-_40457325 0.82 ENSDART00000128442
tnfrsf1b
tumor necrosis factor receptor superfamily, member 1B
chr10_-_44560165 0.82 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr21_+_15592426 0.80 ENSDART00000138207
smarcb1b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr7_+_59677273 0.77 ENSDART00000039535
ENSDART00000132044
trmt44
tRNA methyltransferase 44 homolog
chr22_-_26274177 0.77 ENSDART00000060978
wdr83
WD repeat domain containing 83
chr24_-_25144441 0.76 ENSDART00000152104
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr19_-_19871211 0.76 ENSDART00000170980
evx1
even-skipped homeobox 1
chr24_-_7957581 0.72 ENSDART00000145815
txndc5
thioredoxin domain containing 5
chr5_+_9224051 0.72 ENSDART00000139265
si:ch211-12e13.12
si:ch211-12e13.12
chr21_-_38730557 0.72 ENSDART00000150984
ENSDART00000111885
taf9
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr24_-_25004553 0.70 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr25_+_14697247 0.70 ENSDART00000180747
mpped2
metallophosphoesterase domain containing 2b
chr11_+_2855430 0.63 ENSDART00000172837
kif21b
kinesin family member 21B
chr11_+_31864921 0.62 ENSDART00000180252
diaph3
diaphanous-related formin 3
chr22_+_2769236 0.60 ENSDART00000141836
si:dkey-20i20.10
si:dkey-20i20.10
chr23_-_42876596 0.57 ENSDART00000086156
dlgap4a
discs, large (Drosophila) homolog-associated protein 4a
chr19_+_1673599 0.57 ENSDART00000163127
klhl7
kelch-like family member 7
chr5_+_19933356 0.50 ENSDART00000088819
ankrd13a
ankyrin repeat domain 13A
chr20_+_28803977 0.49 ENSDART00000153351
ENSDART00000038149
fntb
farnesyltransferase, CAAX box, beta
chr25_-_13558172 0.46 ENSDART00000139970
ENSDART00000133789
ENSDART00000144426
ano10b
anoctamin 10b
chr5_-_68093169 0.46 ENSDART00000051849
slc25a11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr16_+_33144306 0.45 ENSDART00000101953
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr16_+_20161805 0.44 ENSDART00000192146
c16h2orf66
chromosome 16 C2orf66 homolog
chr23_+_44427188 0.44 ENSDART00000160207
eif4e2rs1
eukaryotic translation initiation factor 4E family member 2 related sequence 1
chr3_-_31715714 0.44 ENSDART00000051542
ccdc47
coiled-coil domain containing 47
chr3_-_31716157 0.42 ENSDART00000193189
ccdc47
coiled-coil domain containing 47
chr9_-_16133263 0.41 ENSDART00000077187
myo1b
myosin IB
chr9_+_18829360 0.40 ENSDART00000006514
gtf2f2b
general transcription factor IIF, polypeptide 2b
chr13_-_9213207 0.40 ENSDART00000139861
ENSDART00000140524
HTRA2 (1 of many)
si:dkey-33c12.11
chr17_-_35279422 0.40 ENSDART00000181587
adam17a
ADAM metallopeptidase domain 17a
chr25_+_34748860 0.39 ENSDART00000087364
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr20_+_46040666 0.37 ENSDART00000060744
si:dkey-7c18.24
si:dkey-7c18.24
chr18_+_50890749 0.36 ENSDART00000174109
si:ch1073-450f2.1
si:ch1073-450f2.1
chr2_+_30032303 0.36 ENSDART00000151841
rbm33b
RNA binding motif protein 33b
chr10_-_13343831 0.35 ENSDART00000135941
il11ra
interleukin 11 receptor, alpha
chr20_-_9436521 0.32 ENSDART00000133000
zgc:101840
zgc:101840
chr4_-_12997348 0.32 ENSDART00000171451
si:dkey-6a5.3
si:dkey-6a5.3
chr14_+_50937757 0.30 ENSDART00000163865
rnf44
ring finger protein 44
chr16_+_33144112 0.30 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr1_+_55730205 0.28 ENSDART00000148075
adgre10
adhesion G protein-coupled receptor E10
chr18_+_26895994 0.27 ENSDART00000098347
ch25hl1.2
cholesterol 25-hydroxylase like 1, tandem duplicate 2
chr20_-_45060241 0.26 ENSDART00000185227
klhl29
kelch-like family member 29
chr14_+_6535426 0.26 ENSDART00000055961
thg1l
tRNA-histidine guanylyltransferase 1-like
chr13_+_35955562 0.25 ENSDART00000137377
si:ch211-67f13.7
si:ch211-67f13.7
chr13_+_9521629 0.25 ENSDART00000149870
ENSDART00000137666
si:dkey-19p15.4
si:dkey-19p15.4
chr13_-_9045879 0.25 ENSDART00000155463
ENSDART00000140041
ENSDART00000137454
si:dkey-112g5.11
si:dkey-112g5.11
chr13_+_9468535 0.24 ENSDART00000135088
ENSDART00000164270
ENSDART00000099619
ENSDART00000164656
HTRA2 (1 of many)
si:dkey-265c15.6
chr13_+_18321140 0.24 ENSDART00000180947
eif4e1c
eukaryotic translation initiation factor 4E family member 1c
chr14_+_36521005 0.23 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr19_+_9212031 0.23 ENSDART00000052930
ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr16_+_41171949 0.22 ENSDART00000135294
nek11
NIMA-related kinase 11
chr8_+_18555559 0.22 ENSDART00000149523
tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr19_+_8985230 0.22 ENSDART00000018973
scamp3
secretory carrier membrane protein 3
chr9_+_35832294 0.22 ENSDART00000130549
ENSDART00000122169
si:dkey-67c22.2
si:dkey-67c22.2
chr4_-_14185225 0.22 ENSDART00000147061
si:dkey-234l24.8
si:dkey-234l24.8
chr14_+_20918701 0.21 ENSDART00000144736
ENSDART00000148204
zgc:66433
zgc:66433
chr17_-_6514962 0.21 ENSDART00000163514
dnajc5gb
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma b
chr13_-_9159852 0.21 ENSDART00000170185
ENSDART00000158697
ENSDART00000143393
ENSDART00000164973
ENSDART00000159910
HTRA2 (1 of many)
si:dkey-112g5.16
chr18_+_43891051 0.20 ENSDART00000024213
cxcr5
chemokine (C-X-C motif) receptor 5
chr16_-_18960613 0.19 ENSDART00000183197
fhod3b
formin homology 2 domain containing 3b
chr17_-_2834764 0.17 ENSDART00000024027
bdkrb1
bradykinin receptor B1
chr1_-_48615105 0.17 ENSDART00000189744
LO017711.1

chr15_-_25518084 0.16 ENSDART00000158594
hif1al
hypoxia-inducible factor 1, alpha subunit, like
chr2_-_3678029 0.15 ENSDART00000146861
mmp16b
matrix metallopeptidase 16b (membrane-inserted)
chr20_-_19511016 0.14 ENSDART00000168521
snx17
sorting nexin 17
chr15_-_37620167 0.14 ENSDART00000059582
si:ch211-137j23.8
si:ch211-137j23.8
chr3_+_23692462 0.14 ENSDART00000145934
hoxb7a
homeobox B7a
chr15_-_37683768 0.13 ENSDART00000059609
si:dkey-117a8.3
si:dkey-117a8.3
chr7_-_8324927 0.13 ENSDART00000102535
f13a1b
coagulation factor XIII, A1 polypeptide b
chr25_+_16116740 0.12 ENSDART00000139778
far1
fatty acyl CoA reductase 1
chr15_-_37673733 0.12 ENSDART00000154513
si:dkey-117a8.4
si:dkey-117a8.4
chr21_-_20328375 0.12 ENSDART00000079593
slc26a1
solute carrier family 26 (anion exchanger), member 1
chr22_+_5532003 0.11 ENSDART00000106174
si:ch73-256j6.2
si:ch73-256j6.2
chr13_+_23282549 0.11 ENSDART00000101134
khdrbs2
KH domain containing, RNA binding, signal transduction associated 2
chr25_+_6471401 0.11 ENSDART00000132927
snx33
sorting nexin 33
chr16_+_35595312 0.10 ENSDART00000170438
si:ch211-1i11.3
si:ch211-1i11.3
chr15_-_14212777 0.10 ENSDART00000165572
CR925813.1

chr4_-_75681004 0.10 ENSDART00000186296
si:dkey-71l4.5
si:dkey-71l4.5
chr22_+_9761930 0.10 ENSDART00000181107
BX664625.5

chr18_+_44630415 0.10 ENSDART00000098540
bicra
BRD4 interacting chromatin remodeling complex associated protein
chr1_+_29068654 0.10 ENSDART00000053932
cbsa
cystathionine-beta-synthase a
chr15_-_19051152 0.10 ENSDART00000186453
arhgap32a
Rho GTPase activating protein 32a
chr1_+_40801448 0.08 ENSDART00000187394
cpz
carboxypeptidase Z
chr21_-_23503032 0.08 ENSDART00000101117
ncam1a
neural cell adhesion molecule 1a
chr22_+_9114416 0.08 ENSDART00000190169
nlrp15
NACHT, LRR and PYD domains-containing protein 15
chr11_-_11910225 0.07 ENSDART00000159922
si:ch211-69b7.6
si:ch211-69b7.6
chr24_+_22485710 0.07 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr4_+_19700308 0.07 ENSDART00000027919
pax4
paired box 4
chr15_-_37719015 0.07 ENSDART00000154875
si:dkey-117a8.1
si:dkey-117a8.1
chr5_+_7564644 0.07 ENSDART00000192173
CABZ01039096.1

chr23_+_18527028 0.07 ENSDART00000190263
ENSDART00000104545
avpr2ab
arginine vasopressin receptor 2a, duplicate b
chr10_+_36194527 0.06 ENSDART00000076810
or108-1
odorant receptor, family D, subfamily 108, member 1
chr13_+_15701596 0.06 ENSDART00000130832
trmt61a
tRNA methyltransferase 61A
chr21_-_37973081 0.06 ENSDART00000136569
ripply1
ripply transcriptional repressor 1
chr9_+_12444494 0.06 ENSDART00000102430
tmem41aa
transmembrane protein 41aa
chr15_-_37767901 0.06 ENSDART00000154763
si:dkey-42l23.4
si:dkey-42l23.4
chr16_-_26855936 0.06 ENSDART00000167320
ENSDART00000078119
ino80c
INO80 complex subunit C
chr12_+_3078221 0.05 ENSDART00000148835
ENSDART00000149427
sgca
sarcoglycan, alpha
chr4_-_14162327 0.05 ENSDART00000138656
si:dkey-234l24.1
si:dkey-234l24.1
chr14_-_1543834 0.05 ENSDART00000185876
CABZ01109480.1

chr1_-_7975755 0.04 ENSDART00000141765
si:dkey-79f11.7
si:dkey-79f11.7
chr25_+_19666621 0.04 ENSDART00000112746
zgc:171459
zgc:171459
chr1_-_25966068 0.04 ENSDART00000137869
ENSDART00000134192
synpo2b
synaptopodin 2b
chr18_+_34225520 0.04 ENSDART00000126115
v2rl1
vomeronasal 2 receptor, l1
chr4_-_42408339 0.03 ENSDART00000172612
si:ch211-59d8.3
si:ch211-59d8.3
chr2_+_50608099 0.03 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr17_+_24821627 0.03 ENSDART00000112389
wdr43
WD repeat domain 43
chr17_+_24851951 0.03 ENSDART00000180746
cx35.4
connexin 35.4
chr17_+_41081977 0.03 ENSDART00000137091
ENSDART00000143714
babam2
BRISC and BRCA1 A complex member 2
chr8_-_7567815 0.02 ENSDART00000132536
hcfc1b
host cell factor C1b
chr1_+_40801696 0.02 ENSDART00000147497
cpz
carboxypeptidase Z
chr17_+_41081512 0.02 ENSDART00000056742
babam2
BRISC and BRCA1 A complex member 2
chr24_+_20373605 0.02 ENSDART00000112349
plcd1a
phospholipase C, delta 1a
chr4_-_14173138 0.02 ENSDART00000142487
si:dkey-234l24.7
si:dkey-234l24.7
chr4_+_54519511 0.01 ENSDART00000161653
znf974
zinc finger protein 974
chr5_+_27897504 0.01 ENSDART00000130936
adam28
ADAM metallopeptidase domain 28
chr6_+_52877147 0.01 ENSDART00000174370
or137-8
odorant receptor, family H, subfamily 137, member 8
chr8_-_45838277 0.01 ENSDART00000046064
ogdha
oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
chr18_-_46380471 0.00 ENSDART00000144444
ENSDART00000086772
slc19a3b
solute carrier family 19 (thiamine transporter), member 3b
chr21_-_22648007 0.00 ENSDART00000121788
gig2l
grass carp reovirus (GCRV)-induced gene 2l

Network of associatons between targets according to the STRING database.

First level regulatory network of msx1b+msx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0070986 left/right axis specification(GO:0070986)
0.5 1.5 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 2.3 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.5 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.8 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.8 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.8 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.9 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 1.0 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 2.0 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.1 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.1 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 1.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0060021 palate development(GO:0060021)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.0 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0097189 apoptotic body(GO:0097189)
0.2 0.9 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 0.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.8 GO:0035060 brahma complex(GO:0035060)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0045180 basal cortex(GO:0045180)
0.0 0.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0005903 brush border(GO:0005903)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 3.7 GO:0005813 centrosome(GO:0005813)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 2.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 2.0 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 2.3 GO:0002039 p53 binding(GO:0002039)
0.1 0.5 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.9 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.5 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.7 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.9 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.7 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.3 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) FMN binding(GO:0010181) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening