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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for msx2b

Z-value: 0.78

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Transcription factors associated with msx2b

Gene Symbol Gene ID Gene Info
msx2b
ENSDARG00000101023 muscle segment homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx2bdr11_v1_chr21_-_41147818_41147818-0.223.9e-01Click!

Activity profile of msx2b motif

Sorted Z-values of msx2b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_15957041 2.38 ENSDART00000149236
ENSDART00000187500
ENSDART00000176304
ENSDART00000080047
ENSDART00000190068
eps15l1a
epidermal growth factor receptor pathway substrate 15-like 1a
chr12_-_2993095 2.25 ENSDART00000152316
si:dkey-202c14.3
si:dkey-202c14.3
chr14_-_49063157 1.83 ENSDART00000021260
sept8b
septin 8b
chr22_-_15562933 1.82 ENSDART00000141528
ankmy1
ankyrin repeat and MYND domain containing 1
chr11_+_25259058 1.71 ENSDART00000154109
tp53inp2
tumor protein p53 inducible nuclear protein 2
chr17_+_50248152 1.60 ENSDART00000153998
zc2hc1c
zinc finger, C2HC-type containing 1C
chr5_-_61970674 1.60 ENSDART00000143161
znf541
zinc finger protein 541
chr22_-_547748 1.40 ENSDART00000037455
ENSDART00000140101
ccnd3
cyclin D3
chr20_-_29474859 1.40 ENSDART00000152906
ENSDART00000045249
scg5
secretogranin V
chr19_-_47527093 1.32 ENSDART00000171379
ENSDART00000171140
ENSDART00000114886
scg5
secretogranin V
chr7_-_6470431 1.29 ENSDART00000081359
zgc:110425
zgc:110425
chr25_+_26895394 1.28 ENSDART00000155820
si:dkey-42p14.3
si:dkey-42p14.3
chr20_-_43533096 1.22 ENSDART00000145199
pimr134
Pim proto-oncogene, serine/threonine kinase, related 134
chr10_-_16065185 1.16 ENSDART00000187266
si:dkey-184a18.5
si:dkey-184a18.5
chr1_-_55785722 1.15 ENSDART00000142069
ENSDART00000043933
ndufb7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7
chr21_-_5205617 1.15 ENSDART00000145554
ENSDART00000045284
rpl37
ribosomal protein L37
chr1_-_52659548 1.14 ENSDART00000029252
ENSDART00000150862
aptx
aprataxin
chr7_+_34687969 1.11 ENSDART00000182013
ENSDART00000188255
ENSDART00000182728
plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr14_-_41272034 1.11 ENSDART00000191709
ENSDART00000074438
cenpi
centromere protein I
chr14_+_23520986 1.07 ENSDART00000170473
ENSDART00000175970
si:ch211-221f10.2
si:ch211-221f10.2
chr3_+_18398876 1.07 ENSDART00000141100
ENSDART00000138107
rps2
ribosomal protein S2
chr16_-_40508624 1.07 ENSDART00000075718
ndufaf6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr21_-_2299002 1.06 ENSDART00000168712
si:ch73-299h12.6
si:ch73-299h12.6
chr10_-_5016997 1.03 ENSDART00000101414
hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr25_-_28926631 1.00 ENSDART00000112850
etfbkmt
electron transfer flavoprotein beta subunit lysine methyltransferase
chr20_+_36628059 0.99 ENSDART00000062898
ephx1
epoxide hydrolase 1, microsomal (xenobiotic)
chr24_-_26328721 0.96 ENSDART00000125468
apodb
apolipoprotein Db
chr12_-_48477031 0.94 ENSDART00000105176
ndufb8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr15_+_36309070 0.89 ENSDART00000157034
gmnc
geminin coiled-coil domain containing
chr21_+_38002879 0.89 ENSDART00000065183
cldn2
claudin 2
chr10_+_2715548 0.86 ENSDART00000130793
grk5
G protein-coupled receptor kinase 5
chr22_-_30973791 0.81 ENSDART00000104728
ssuh2.2
ssu-2 homolog, tandem duplicate 2
chr21_-_44009169 0.81 ENSDART00000028960
ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr23_+_35714574 0.79 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr8_+_23738122 0.79 ENSDART00000062983
rpl10a
ribosomal protein L10a
chr2_+_33747509 0.79 ENSDART00000134187
si:dkey-31m5.5
si:dkey-31m5.5
chr16_-_35394422 0.76 ENSDART00000180593
si:dkey-34d22.3
si:dkey-34d22.3
chr5_+_24882633 0.74 ENSDART00000111302
rhbdd3
rhomboid domain containing 3
chr1_+_34203817 0.69 ENSDART00000191432
ENSDART00000046094
arl6
ADP-ribosylation factor-like 6
chr7_+_65309738 0.69 ENSDART00000169228
vat1l
vesicle amine transport 1-like
chr19_-_1947403 0.68 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
znrf2a
zinc and ring finger 2a
chr14_-_32089117 0.68 ENSDART00000158014
si:ch211-69b22.5
si:ch211-69b22.5
chr11_+_6881001 0.66 ENSDART00000170331
klhl26
kelch-like family member 26
chr1_+_42225060 0.65 ENSDART00000138740
ENSDART00000101306
ctnna2
catenin (cadherin-associated protein), alpha 2
chr2_+_6127593 0.65 ENSDART00000184007
fzr1b
fizzy/cell division cycle 20 related 1b
chr3_-_31619463 0.64 ENSDART00000124559
moto
minamoto
chr3_-_33427803 0.64 ENSDART00000075495
rpl23
ribosomal protein L23
chr3_-_13461361 0.62 ENSDART00000080807
fbxw9
F-box and WD repeat domain containing 9
chr9_-_24031461 0.62 ENSDART00000021218
rpe
ribulose-5-phosphate-3-epimerase
chr23_-_35064785 0.62 ENSDART00000172240
BX294434.1

chr11_+_11360641 0.61 ENSDART00000159765
si:dkey-23f9.7
si:dkey-23f9.7
chr4_+_14900042 0.60 ENSDART00000018261
akr1b1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr21_+_19062124 0.57 ENSDART00000134746
rpl17
ribosomal protein L17
chr4_-_5455506 0.55 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
si:dkey-14d8.22
chr20_-_2134620 0.55 ENSDART00000064375
tmem244
transmembrane protein 244
chr2_+_38373272 0.55 ENSDART00000113111
psmb5
proteasome subunit beta 5
chr6_+_59984772 0.52 ENSDART00000048449
mtrf1
mitochondrial translational release factor 1
chr15_-_19669770 0.51 ENSDART00000152707
si:dkey-4p15.3
si:dkey-4p15.3
chr15_+_17074185 0.50 ENSDART00000046648
clptm1
cleft lip and palate associated transmembrane protein 1
chr6_-_30210378 0.50 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr5_-_2689753 0.50 ENSDART00000172699
gng10
guanine nucleotide binding protein (G protein), gamma 10
chr23_+_43489182 0.50 ENSDART00000162062
znf341
zinc finger protein 341
chr15_-_23784600 0.48 ENSDART00000059354
rad1
RAD1 homolog (S. pombe)
chr11_+_3254524 0.48 ENSDART00000159459
pmela
premelanosome protein a
chr8_+_17069577 0.47 ENSDART00000131847
si:dkey-190g11.3
si:dkey-190g11.3
chr22_-_18164671 0.47 ENSDART00000014057
rfxank
regulatory factor X-associated ankyrin-containing protein
chr13_-_4223955 0.46 ENSDART00000113060
dnph1
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr15_+_1796313 0.44 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr14_-_8453192 0.43 ENSDART00000136947
eif1ad
eukaryotic translation initiation factor 1A domain containing
chr4_+_5506952 0.43 ENSDART00000032857
ENSDART00000160222
mapk11
mitogen-activated protein kinase 11
chr11_+_25539698 0.43 ENSDART00000035602
cxxc1b
CXXC finger protein 1b
chr23_-_24493768 0.42 ENSDART00000135559
ENSDART00000046933
sult1st5
sulfotransferase family 1, cytosolic sulfotransferase 5
chr5_-_7834582 0.42 ENSDART00000162626
ENSDART00000157661
pdlim5a
PDZ and LIM domain 5a
chr5_-_38777852 0.42 ENSDART00000131603
si:dkey-58f10.4
si:dkey-58f10.4
chr1_+_11977426 0.42 ENSDART00000103399
tspan5b
tetraspanin 5b
chr20_+_38031439 0.41 ENSDART00000153208
galnt14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_-_26923957 0.41 ENSDART00000182390
skiv2l
SKI2 homolog, superkiller viralicidic activity 2-like
chr24_-_21923930 0.40 ENSDART00000131944
tagln3b
transgelin 3b
chr14_-_7137808 0.40 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr14_+_35369979 0.40 ENSDART00000144702
ENSDART00000169712
clint1a
clathrin interactor 1a
chr22_-_18164835 0.39 ENSDART00000143189
rfxank
regulatory factor X-associated ankyrin-containing protein
chr8_+_22930627 0.39 ENSDART00000187860
sypa
synaptophysin a
chr16_+_41570653 0.38 ENSDART00000102665
aste1a
asteroid homolog 1a
chr15_+_32711663 0.37 ENSDART00000157854
ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr20_-_53366137 0.37 ENSDART00000146001
wasf1
WAS protein family, member 1
chr11_-_44484952 0.36 ENSDART00000166674
ENSDART00000188016
mfn1b
mitofusin 1b
chr9_-_2572790 0.36 ENSDART00000135076
ENSDART00000016710
scrn3
secernin 3
chr5_+_13427826 0.35 ENSDART00000083359
sec14l8
SEC14-like lipid binding 8
chr19_-_22346582 0.35 ENSDART00000045675
ENSDART00000169065
slc52a2
zgc:109744
solute carrier family 52 (riboflavin transporter), member 2
zgc:109744
chr10_+_9697097 0.35 ENSDART00000167821
rabgap1
RAB GTPase activating protein 1
chr23_-_31974060 0.35 ENSDART00000168087
BX927210.1

chr5_+_67268110 0.33 ENSDART00000148116
si:ch211-110p13.9
si:ch211-110p13.9
chr24_-_3783497 0.32 ENSDART00000158354
adarb2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr14_-_4273396 0.31 ENSDART00000127318
frmpd1b
FERM and PDZ domain containing 1b
chr3_+_25195966 0.30 ENSDART00000112338
il2rb
interleukin 2 receptor, beta
chr7_-_24005268 0.30 ENSDART00000173608
si:dkey-183c6.9
si:dkey-183c6.9
chr25_-_18953322 0.30 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr3_-_44059902 0.29 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
il4r.1
interleukin 4 receptor, tandem duplicate 1
chr24_-_31843173 0.29 ENSDART00000185782
steap2
STEAP family member 2, metalloreductase
chr10_-_26430168 0.29 ENSDART00000128894
dchs1b
dachsous cadherin-related 1b
chr20_+_34870517 0.29 ENSDART00000191797
ankef1a
ankyrin repeat and EF-hand domain containing 1a
chr5_+_66433287 0.29 ENSDART00000170757
kntc1
kinetochore associated 1
chr12_-_5728755 0.28 ENSDART00000105887
dlx4b
distal-less homeobox 4b
chr8_-_44004135 0.28 ENSDART00000136269
rimbp2
RIMS binding protein 2
chr6_-_27891961 0.28 ENSDART00000155116
im:7152348
im:7152348
chr23_+_40460333 0.28 ENSDART00000184658
soga3b
SOGA family member 3b
chr7_-_13362590 0.27 ENSDART00000091616
sdhaf2
succinate dehydrogenase complex assembly factor 2
chr15_-_28082310 0.27 ENSDART00000152620
dhrs13a.3
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr22_-_15717897 0.27 ENSDART00000008424
malt2
MALT paracaspase 2
chr17_-_51199558 0.27 ENSDART00000154532
paplna
papilin a, proteoglycan-like sulfated glycoprotein
chr15_-_17813680 0.26 ENSDART00000158556
CT573342.2

chr7_+_6990510 0.25 ENSDART00000138948
ccs
copper chaperone for superoxide dismutase
chr5_+_24179307 0.25 ENSDART00000051552
mpdu1a
mannose-P-dolichol utilization defect 1a
chr5_-_9216758 0.25 ENSDART00000134896
ENSDART00000147000
lrp13
low-density lipoprotein receptor related-protein 13
chr15_-_4094888 0.24 ENSDART00000166307
TM4SF19
si:dkey-83h2.3
chr19_-_12392819 0.24 ENSDART00000052239
ptpn2b
protein tyrosine phosphatase, non-receptor type 2, b
chr11_+_42765963 0.23 ENSDART00000156080
ENSDART00000179888
tdrd3
tudor domain containing 3
chr18_-_33979693 0.23 ENSDART00000021215
si:ch211-203b20.7
si:ch211-203b20.7
chr12_+_5081759 0.23 ENSDART00000164178
prrt2
proline-rich transmembrane protein 2
chr6_-_55347616 0.22 ENSDART00000172081
pcif1
PDX1 C-terminal inhibiting factor 1
chr15_-_3976035 0.22 ENSDART00000168061
si:ch73-309g22.1
si:ch73-309g22.1
chr10_+_8690936 0.22 ENSDART00000144218
si:dkey-27b3.4
si:dkey-27b3.4
chr21_+_10712823 0.21 ENSDART00000123476
lman1
lectin, mannose-binding, 1
chr8_-_40276035 0.21 ENSDART00000185301
ENSDART00000187610
ENSDART00000053158
ENSDART00000162020
kdm2ba
lysine (K)-specific demethylase 2Ba
chr17_+_12658411 0.20 ENSDART00000139918
gpn1
GPN-loop GTPase 1
chr5_-_66768121 0.20 ENSDART00000141095
FERMT3 (1 of many)
im:7154036
chr21_+_43402794 0.20 ENSDART00000185572
frmd7
FERM domain containing 7
chr16_-_50897887 0.19 ENSDART00000156985
si:ch73-90p23.1
si:ch73-90p23.1
chr13_+_23988442 0.18 ENSDART00000010918
agt
angiotensinogen
chr3_-_17871846 0.18 ENSDART00000074478
ENSDART00000187941
nkiras2
NFKB inhibitor interacting Ras-like 2
chr15_+_19646902 0.17 ENSDART00000179822
lim2.3
lens intrinsic membrane protein 2.3
chr25_-_24248000 0.17 ENSDART00000073527
spty2d1
SPT2 chromatin protein domain containing 1
chr6_+_4033832 0.17 ENSDART00000159952
sema5bb
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr20_-_23426339 0.17 ENSDART00000004625
zar1
zygote arrest 1
chr14_-_11456724 0.16 ENSDART00000110424
si:ch211-153b23.4
si:ch211-153b23.4
chr23_-_41965557 0.16 ENSDART00000144183
slc1a7b
solute carrier family 1 (glutamate transporter), member 7b
chr15_+_7064819 0.16 ENSDART00000155268
pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr24_-_40860603 0.15 ENSDART00000188032
CU633479.7

chr14_-_35462148 0.15 ENSDART00000045809
srpx2
sushi-repeat containing protein, X-linked 2
chr24_-_14712427 0.15 ENSDART00000176316
jph1a
junctophilin 1a
chr24_-_24849091 0.15 ENSDART00000133649
ENSDART00000038290
crhb
corticotropin releasing hormone b
chr11_+_37178271 0.14 ENSDART00000161771
itih3b
inter-alpha-trypsin inhibitor heavy chain 3b
chr10_-_11353101 0.13 ENSDART00000092110
lin54
lin-54 DREAM MuvB core complex component
chr25_+_30442389 0.13 ENSDART00000003346
pdcd2l
programmed cell death 2-like
chr6_+_6828167 0.13 ENSDART00000181284
si:ch211-85n16.4
si:ch211-85n16.4
chr18_+_10884996 0.13 ENSDART00000147613
mical3a
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr19_-_3255725 0.12 ENSDART00000105165
illr1
immune-related, lectin-like receptor 1
chr7_+_69356661 0.12 ENSDART00000177049
CABZ01083862.1

chr13_+_8958438 0.12 ENSDART00000165721
ENSDART00000169398
haao
3-hydroxyanthranilate 3,4-dioxygenase
chr10_+_39952995 0.12 ENSDART00000183077
BX927333.1

chr5_+_9246458 0.12 ENSDART00000081772
susd1
sushi domain containing 1
chr11_+_29856032 0.12 ENSDART00000079150
grpr
gastrin-releasing peptide receptor
chr7_-_41812355 0.12 ENSDART00000016105
vps35
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr8_-_16788626 0.11 ENSDART00000191652
CR759968.2

chr8_+_3426522 0.11 ENSDART00000159466
CU929199.1

chr3_+_24571163 0.11 ENSDART00000123017
sp100.3
SP110 nuclear body protein, tandem duplicate 3
chr14_+_23874062 0.11 ENSDART00000172149
sh3rf2
SH3 domain containing ring finger 2
chr1_+_12068800 0.10 ENSDART00000055566
xpa
xeroderma pigmentosum, complementation group A
chr10_-_41157135 0.10 ENSDART00000134851
aak1b
AP2 associated kinase 1b
chr2_-_24398324 0.10 ENSDART00000165226
zgc:154006
zgc:154006
chr12_+_28574863 0.10 ENSDART00000153284
tbkbp1
TBK1 binding protein 1
chr23_-_44903048 0.10 ENSDART00000149103
fhdc5
FH2 domain containing 5
chr17_+_8542203 0.10 ENSDART00000158873
CU462878.2

chr17_+_31185276 0.10 ENSDART00000062887
disp2
dispatched homolog 2 (Drosophila)
chr2_+_37176814 0.10 ENSDART00000048277
ENSDART00000176827
copa
coatomer protein complex, subunit alpha
chr11_+_17984167 0.09 ENSDART00000020283
ENSDART00000188329
rpusd4
RNA pseudouridylate synthase domain containing 4
chr15_+_17031111 0.09 ENSDART00000175378
plin2
perilipin 2
chr9_+_29548195 0.09 ENSDART00000176057
rnf17
ring finger protein 17
chr13_+_50151407 0.08 ENSDART00000031858
gpr137ba
G protein-coupled receptor 137Ba
chr17_+_45607580 0.08 ENSDART00000122583
si:ch211-202f3.4
si:ch211-202f3.4
chr4_-_6373735 0.08 ENSDART00000140100
MDFIC
si:ch73-156e19.1
chr21_-_31013817 0.08 ENSDART00000065504
ncbp3
nuclear cap binding subunit 3
chr6_-_15641686 0.07 ENSDART00000135583
mlpha
melanophilin a
chr22_-_31672566 0.07 ENSDART00000128247
lsm3
LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr11_+_17984354 0.07 ENSDART00000179986
rpusd4
RNA pseudouridylate synthase domain containing 4
chr14_-_12307522 0.06 ENSDART00000163900
myot
myotilin
chr18_-_7539469 0.06 ENSDART00000101296
si:dkey-30c15.2
si:dkey-30c15.2
chr19_+_12406583 0.06 ENSDART00000013865
ENSDART00000151535
seh1l
SEH1-like (S. cerevisiae)
chr6_-_29515709 0.06 ENSDART00000180205
pex5la
peroxisomal biogenesis factor 5-like a
chr3_+_22935183 0.06 ENSDART00000157378
hdac5
histone deacetylase 5
chr4_+_78058635 0.06 ENSDART00000162631
ENSDART00000191619
CABZ01075274.1

chr19_+_20540843 0.05 ENSDART00000192500
kcnh8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr17_-_6730247 0.05 ENSDART00000031091
vsnl1b
visinin-like 1b
chr2_-_10600950 0.05 ENSDART00000160216
BX323564.1

chr20_-_20355577 0.04 ENSDART00000018500
hif1ab
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b
chr14_+_1007169 0.04 ENSDART00000172676
f8
coagulation factor VIII, procoagulant component
chr10_+_25726694 0.03 ENSDART00000140308
ugt5d1
UDP glucuronosyltransferase 5 family, polypeptide D1
chr25_+_25085349 0.03 ENSDART00000192166
si:ch73-182e20.4
si:ch73-182e20.4
chr2_-_23778180 0.03 ENSDART00000136782
si:dkey-24c2.7
si:dkey-24c2.7
chr22_+_31295791 0.03 ENSDART00000092447
grip2b
glutamate receptor interacting protein 2b
chr17_-_10122204 0.03 ENSDART00000160751
BX088587.1

chr18_+_7073130 0.03 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr13_-_40238813 0.02 ENSDART00000044963
loxl4
lysyl oxidase-like 4
chr18_+_33264609 0.02 ENSDART00000050639
v2ra20
vomeronasal 2 receptor, a20
chr15_+_17030941 0.02 ENSDART00000062069
plin2
perilipin 2
chr6_-_46861676 0.02 ENSDART00000188712
ENSDART00000190148
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr7_+_29512673 0.02 ENSDART00000173895
si:dkey-182o15.5
si:dkey-182o15.5
chr7_+_15313443 0.02 ENSDART00000045385
mespba
mesoderm posterior ba
chr16_+_14707960 0.02 ENSDART00000137912
col14a1a
collagen, type XIV, alpha 1a
chr19_+_22727940 0.02 ENSDART00000052509
trhrb
thyrotropin-releasing hormone receptor b

Network of associatons between targets according to the STRING database.

First level regulatory network of msx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.2 1.1 GO:0000012 single strand break repair(GO:0000012)
0.2 0.6 GO:0019323 pentose catabolic process(GO:0019323)
0.2 0.9 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 0.5 GO:0070126 mitochondrial translational termination(GO:0070126)
0.2 0.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 0.5 GO:0097435 fibril organization(GO:0097435)
0.2 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.4 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 2.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.3 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 1.4 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.3 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.6 GO:0007141 male meiosis I(GO:0007141)
0.1 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.3 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 0.3 GO:0015677 copper ion import(GO:0015677)
0.1 1.3 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 2.4 GO:0046883 regulation of hormone secretion(GO:0046883)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 1.1 GO:0034508 centromere complex assembly(GO:0034508)
0.0 1.0 GO:0009636 response to toxic substance(GO:0009636)
0.0 1.2 GO:0000302 response to reactive oxygen species(GO:0000302)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.0 0.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0043420 anthranilate metabolic process(GO:0043420)
0.0 0.1 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.2 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.4 GO:0045682 regulation of epidermis development(GO:0045682)
0.0 0.5 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.4 GO:0016203 muscle attachment(GO:0016203)
0.0 1.0 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.7 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 1.8 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.4 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990) endocrine process(GO:0050886)
0.0 2.5 GO:0016197 endosomal transport(GO:0016197)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.5 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.1 2.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.8 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 2.7 GO:0031514 motile cilium(GO:0031514)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 1.1 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 1.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.7 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.3 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 1.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 2.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 4.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress