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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mta3

Z-value: 0.27

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Transcription factors associated with mta3

Gene Symbol Gene ID Gene Info
mta3
ENSDARG00000054903 metastasis associated 1 family, member 3
mta3
ENSDARG00000113436 metastasis associated 1 family, member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mta3dr11_v1_chr12_+_25223843_252238730.581.1e-02Click!

Activity profile of mta3 motif

Sorted Z-values of mta3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_2578026 0.83 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr5_-_54712159 0.61 ENSDART00000149207
ccnb1
cyclin B1
chr12_+_13348918 0.35 ENSDART00000181373
rnasen
ribonuclease type III, nuclear
chr6_+_3334392 0.29 ENSDART00000133707
ENSDART00000130879
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr16_-_280835 0.29 ENSDART00000190541
LO017917.1

chr23_+_2825940 0.28 ENSDART00000135781
plcg1
phospholipase C, gamma 1
chr21_+_44581654 0.27 ENSDART00000187201
ENSDART00000180360
ENSDART00000191543
ENSDART00000180039
ENSDART00000186308
TMEM164
transmembrane protein 164
chr5_+_20453874 0.22 ENSDART00000124545
ENSDART00000008402
sart3
squamous cell carcinoma antigen recognized by T cells 3
chr3_+_16566361 0.22 ENSDART00000132869
ENSDART00000080771
slc6a16a
solute carrier family 6, member 16a
chr13_+_1100197 0.21 ENSDART00000139560
ppp3r1a
protein phosphatase 3, regulatory subunit B, alpha a
chr20_+_9474841 0.21 ENSDART00000053847
rad51b
RAD51 paralog B
chr25_-_35143360 0.19 ENSDART00000188033
zgc:165555
zgc:165555
chr5_-_23800376 0.18 ENSDART00000134184
gbgt1l4
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr18_-_45736 0.17 ENSDART00000148373
ENSDART00000148950
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr13_+_31545812 0.17 ENSDART00000076527
ppm1aa
protein phosphatase, Mg2+/Mn2+ dependent, 1Aa
chr17_-_25630822 0.17 ENSDART00000126201
ENSDART00000105503
ENSDART00000151878
rab3gap2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr2_-_22535 0.16 ENSDART00000157877
CABZ01092282.1

chr15_-_25198107 0.16 ENSDART00000159793
mnta
MAX network transcriptional repressor a
chr20_-_33675676 0.16 ENSDART00000147168
rock2b
rho-associated, coiled-coil containing protein kinase 2b
chr4_-_13255700 0.15 ENSDART00000162277
ENSDART00000026593
grip1
glutamate receptor interacting protein 1
chr1_+_14454663 0.14 ENSDART00000005067
rbpja
recombination signal binding protein for immunoglobulin kappa J region a
chr7_+_1579510 0.13 ENSDART00000190525
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr13_+_23093743 0.12 ENSDART00000148034
pik3ap1
phosphoinositide-3-kinase adaptor protein 1
chr18_-_46010 0.11 ENSDART00000052641
gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_-_20678300 0.10 ENSDART00000088639
wscd2
WSC domain containing 2
chr6_+_3334710 0.09 ENSDART00000132848
st3gal3a
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr25_-_35106751 0.08 ENSDART00000180682
ENSDART00000073457
zgc:194989
zgc:194989
chr21_+_45712247 0.08 ENSDART00000163982
camlg
calcium modulating ligand
chr14_-_237130 0.08 ENSDART00000164988
bod1l1
biorientation of chromosomes in cell division 1-like 1
chr3_-_5228137 0.06 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr14_-_2369849 0.05 ENSDART00000180422
ENSDART00000189731
ENSDART00000111748
pcdhb
protocadherin b
chr7_+_1579236 0.05 ENSDART00000172830
supt16h
SPT16 homolog, facilitates chromatin remodeling subunit
chr23_-_24825863 0.05 ENSDART00000112493
syt6a
synaptotagmin VIa
chr19_+_41769135 0.03 ENSDART00000087096
tinagl1
tubulointerstitial nephritis antigen-like 1
chr22_-_7809904 0.03 ENSDART00000182269
ENSDART00000097201
ENSDART00000138522
si:ch73-44m9.3
si:ch73-44m9.1
si:ch73-44m9.3
si:ch73-44m9.1
chr22_-_193234 0.02 ENSDART00000131067
fbxo42
F-box protein 42
chr25_+_27744293 0.02 ENSDART00000103519
ENSDART00000149456
wasla
Wiskott-Aldrich syndrome-like a
chr16_-_17207754 0.02 ENSDART00000063804
wu:fj39g12
wu:fj39g12
chr4_-_34799395 0.01 ENSDART00000170744
si:dkey-146m20.13
si:dkey-146m20.13
chr5_+_45139196 0.01 ENSDART00000113738
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_13069168 0.00 ENSDART00000192832
prkag2b
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr6_-_12270226 0.00 ENSDART00000180473
pkp4
plakophilin 4
chr4_+_69577362 0.00 ENSDART00000160913
znf1030
zinc finger protein 1030

Network of associatons between targets according to the STRING database.

First level regulatory network of mta3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1 0.3 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.8 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0072314 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.2 GO:0099638 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes