ISMARA results: mta3

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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mta3

Z-value: 0.27

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Transcription factors associated with mta3

Gene Symbol	Gene ID	Gene Info
mta3 NCBI UniProt	ENSDARG00000054903	metastasis associated 1 family, member 3
mta3 NCBI UniProt	ENSDARG00000113436	metastasis associated 1 family, member 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
mta3	dr11_v1_chr12_+_25223843_25223873	0.58	1.1e-02	Click!

Activity profile of mta3 motif

Sorted Z-values of mta3 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr17_-_2578026 Show fit	0.83	ENSDART00000065821	zp3.2 NCBI UniProt Show fit	zona pellucida glycoprotein 3, tandem duplicate 2
chr5_-_54712159 Show fit	0.61	ENSDART00000149207	ccnb1 NCBI UniProt Show fit	cyclin B1
chr12_+_13348918 Show fit	0.35	ENSDART00000181373	rnasen NCBI UniProt Show fit	ribonuclease type III, nuclear
chr6_+_3334392 Show fit	0.29	ENSDART00000133707 ENSDART00000130879	st3gal3a NCBI UniProt Show fit	ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr16_-_280835 Show fit	0.29	ENSDART00000190541	LO017917.1 NCBI UniProt Show fit
chr23_+_2825940 Show fit	0.28	ENSDART00000135781	plcg1 NCBI UniProt Show fit	phospholipase C, gamma 1
chr21_+_44581654 Show fit	0.27	ENSDART00000187201 ENSDART00000180360 ENSDART00000191543 ENSDART00000180039 ENSDART00000186308	TMEM164 NCBI UniProt Show fit	transmembrane protein 164
chr5_+_20453874 Show fit	0.22	ENSDART00000124545 ENSDART00000008402	sart3 NCBI UniProt Show fit	squamous cell carcinoma antigen recognized by T cells 3
chr3_+_16566361 Show fit	0.22	ENSDART00000132869 ENSDART00000080771	slc6a16a NCBI UniProt Show fit	solute carrier family 6, member 16a
chr13_+_1100197 Show fit	0.21	ENSDART00000139560	ppp3r1a NCBI UniProt Show fit	protein phosphatase 3, regulatory subunit B, alpha a

Showing 1 to 10 of 43 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of mta3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	GO:0035803	binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1	0.6	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.1	0.3	GO:0006601	creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1	0.3	GO:0035477	regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1	0.2	GO:1903003	positive regulation of protein deubiquitination(GO:1903003)
0.0	0.2	GO:0099638	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0	0.2	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0072314	glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0	0.1	GO:0070650	actin filament bundle distribution(GO:0070650)

Showing 1 to 9 of 9 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0097125	cyclin B1-CDK1 complex(GO:0097125)
0.0	0.2	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.2	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0035101	FACT complex(GO:0035101)

Showing 1 to 4 of 4 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0035804	structural constituent of egg coat(GO:0035804)
0.1	0.4	GO:0008118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0072518	Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)

Showing 1 to 6 of 6 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway

Showing 1 to 2 of 2 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling

Showing 1 to 2 of 2 entries

Results for mta3

Z-value: 0.27

Motif logo

Transcription factors associated with mta3

Activity-expression correlation:

Activity profile of mta3 motif

Sorted Z-values of mta3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of mta3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: