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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for mycb

Z-value: 0.55

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Transcription factors associated with mycb

Gene Symbol Gene ID Gene Info
mycb
ENSDARG00000007241 MYC proto-oncogene, bHLH transcription factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycbdr11_v1_chr2_+_32016516_320165160.865.2e-06Click!

Activity profile of mycb motif

Sorted Z-values of mycb motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_26834043 1.73 ENSDART00000087202
si:dkey-44g23.5
si:dkey-44g23.5
chr15_-_17099560 0.99 ENSDART00000101724
mos
v-mos Moloney murine sarcoma viral oncogene homolog
chr9_-_27391908 0.96 ENSDART00000135221
nepro
nucleolus and neural progenitor protein
chr8_-_46386024 0.93 ENSDART00000136602
ENSDART00000060919
ENSDART00000137472
qars
glutaminyl-tRNA synthetase
chr12_-_4301234 0.84 ENSDART00000152377
ENSDART00000152521
ca15b
carbonic anhydrase XVb
chr13_-_35907768 0.84 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr9_-_11587070 0.81 ENSDART00000030995
umps
uridine monophosphate synthetase
chr20_-_25631256 0.76 ENSDART00000048164
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr1_-_19648227 0.76 ENSDART00000054574
polr1e
polymerase (RNA) I polypeptide E
chr5_-_30080332 0.72 ENSDART00000140049
bco2a
beta-carotene oxygenase 2a
chr1_+_5485799 0.68 ENSDART00000022307
atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr3_+_23029934 0.67 ENSDART00000110343
nags
N-acetylglutamate synthase
chr17_-_48705993 0.66 ENSDART00000030934
kcnk5a
potassium channel, subfamily K, member 5a
chr12_+_33975065 0.62 ENSDART00000036649
sfxn2
sideroflexin 2
chr24_-_39518599 0.61 ENSDART00000145606
ENSDART00000031486
lyrm1
LYR motif containing 1
chr17_+_24318753 0.61 ENSDART00000064083
otx1
orthodenticle homeobox 1
chr2_-_42375275 0.60 ENSDART00000026339
gtpbp4
GTP binding protein 4
chr5_-_3927692 0.60 ENSDART00000146840
ENSDART00000058346
c1qbp
complement component 1, q subcomponent binding protein
chr22_+_1440702 0.59 ENSDART00000165677
si:dkeyp-53d3.3
si:dkeyp-53d3.3
chr18_+_5850837 0.55 ENSDART00000013150
cog8
component of oligomeric golgi complex 8
chr24_+_36317544 0.55 ENSDART00000048640
ENSDART00000156096
pus3
pseudouridylate synthase 3
chr7_-_49800755 0.54 ENSDART00000180072
fjx1
four jointed box 1
chr1_-_26676391 0.54 ENSDART00000152492
trmo
tRNA methyltransferase O
chr1_-_26675969 0.53 ENSDART00000054184
trmo
tRNA methyltransferase O
chr21_+_22846757 0.52 ENSDART00000185766
birc2
baculoviral IAP repeat containing 2
chr12_-_33359654 0.51 ENSDART00000001907
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr9_-_12888082 0.50 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
si:ch211-167j6.3
chr17_+_51682429 0.49 ENSDART00000004379
nol10
nucleolar protein 10
chr9_+_38158570 0.49 ENSDART00000059549
ENSDART00000133060
nifk
nucleolar protein interacting with the FHA domain of MKI67
chr21_+_4509483 0.48 ENSDART00000025612
phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr14_+_22076596 0.48 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr4_-_14192254 0.40 ENSDART00000143804
pus7l
pseudouridylate synthase 7-like
chr15_+_6652396 0.40 ENSDART00000192813
ENSDART00000157678
nop53
NOP53 ribosome biogenesis factor
chr11_+_25485774 0.39 ENSDART00000026249
gnl3l
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr19_+_42983613 0.39 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr20_+_25625872 0.38 ENSDART00000078385
ppat
phosphoribosyl pyrophosphate amidotransferase
chr9_+_907459 0.38 ENSDART00000034850
ENSDART00000144114
dbi
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr12_-_33359052 0.38 ENSDART00000135943
slc16a3
solute carrier family 16 (monocarboxylate transporter), member 3
chr21_+_40443118 0.38 ENSDART00000190675
ssh2b
slingshot protein phosphatase 2b
chr2_+_9946121 0.38 ENSDART00000100696
tsen15
TSEN15 tRNA splicing endonuclease subunit
chr4_-_2945306 0.37 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr8_+_26059677 0.37 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr11_+_3959495 0.36 ENSDART00000122953
gnl3
guanine nucleotide binding protein-like 3 (nucleolar)
chr6_-_39080630 0.36 ENSDART00000021520
ENSDART00000128308
eif4bb
eukaryotic translation initiation factor 4Bb
chr22_-_28777557 0.35 ENSDART00000135214
ENSDART00000131761
ENSDART00000005112
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr13_-_3516473 0.34 ENSDART00000146240
prkn
parkin RBR E3 ubiquitin protein ligase
chr2_-_20715094 0.33 ENSDART00000155439
dusp12
dual specificity phosphatase 12
chr9_-_27719998 0.33 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr14_-_28568107 0.32 ENSDART00000042850
ENSDART00000145502
insb
preproinsulin b
chr13_-_280652 0.32 ENSDART00000193627
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr10_+_29771256 0.32 ENSDART00000193195
hyou1
hypoxia up-regulated 1
chr22_-_28777374 0.31 ENSDART00000188206
si:dkeyp-34c12.1
si:dkeyp-34c12.1
chr18_+_42970208 0.31 ENSDART00000084454
nectin1b
nectin cell adhesion molecule 1b
chr10_-_14929630 0.31 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
smad2
SMAD family member 2
chr10_+_29850330 0.31 ENSDART00000168898
hspa8
heat shock protein 8
chr13_+_13930263 0.31 ENSDART00000079154
rpia
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr10_+_29849977 0.31 ENSDART00000180242
hspa8
heat shock protein 8
chr13_-_280827 0.30 ENSDART00000144819
slc30a6
solute carrier family 30 (zinc transporter), member 6
chr24_+_16905188 0.29 ENSDART00000066760
cct5
chaperonin containing TCP1, subunit 5 (epsilon)
chr8_+_31799410 0.29 ENSDART00000141226
oxct1a
3-oxoacid CoA transferase 1a
chr8_-_13678415 0.29 ENSDART00000134153
ENSDART00000143331
si:dkey-258f14.3
si:dkey-258f14.3
chr18_-_5850683 0.29 ENSDART00000082087
nip7
NIP7, nucleolar pre-rRNA processing protein
chr9_-_11676491 0.28 ENSDART00000022358
zc3h15
zinc finger CCCH-type containing 15
chr21_+_17768174 0.27 ENSDART00000141380
rxraa
retinoid X receptor, alpha a
chr7_+_41322407 0.26 ENSDART00000114076
ENSDART00000139093
dph2
DPH2 homolog (S. cerevisiae)
chr7_+_69449814 0.25 ENSDART00000109644
ctdnep1b
CTD nuclear envelope phosphatase 1b
chr15_-_43978141 0.25 ENSDART00000041249
chordc1a
cysteine and histidine-rich domain (CHORD) containing 1a
chr10_+_2232023 0.24 ENSDART00000097695
cntnap3
contactin associated protein like 3
chr5_-_8765428 0.24 ENSDART00000167793
mybbp1a
MYB binding protein (P160) 1a
chr6_+_12006557 0.24 ENSDART00000128024
wdsub1
WD repeat, sterile alpha motif and U-box domain containing 1
chr11_+_6456146 0.24 ENSDART00000036939
gadd45ba
growth arrest and DNA-damage-inducible, beta a
chr14_-_12822 0.24 ENSDART00000180650
ENSDART00000188819
msx1a
muscle segment homeobox 1a
chr5_-_54714525 0.24 ENSDART00000150138
ENSDART00000150070
ccnb1
cyclin B1
chr22_+_17261801 0.24 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tdrd5
tudor domain containing 5
chr14_+_28432737 0.24 ENSDART00000026846
pin4
protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr23_-_38160024 0.24 ENSDART00000087112
pfdn4
prefoldin subunit 4
chr9_-_27720612 0.23 ENSDART00000000566
gtf2e1
general transcription factor IIE, polypeptide 1, alpha
chr19_+_1005933 0.22 ENSDART00000191953
zdhhc3b
zinc finger, DHHC-type containing 3b
chr11_-_21303946 0.22 ENSDART00000185786
RASSF5
si:dkey-85p17.3
chr8_-_39977026 0.22 ENSDART00000141707
asphd2
aspartate beta-hydroxylase domain containing 2
chr22_+_835728 0.21 ENSDART00000003325
dennd2db
DENN/MADD domain containing 2Db
chr5_+_68807170 0.20 ENSDART00000017849
her7
hairy and enhancer of split related-7
chr8_-_2246143 0.20 ENSDART00000135835
si:dkeyp-117b11.3
si:dkeyp-117b11.3
chr5_-_54714789 0.20 ENSDART00000063357
ccnb1
cyclin B1
chr18_-_5103931 0.19 ENSDART00000188091
pdcd10a
programmed cell death 10a
chr21_-_11199366 0.19 ENSDART00000167666
dnajc21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr1_-_14533611 0.19 ENSDART00000180678
CR847936.6

chr2_+_50999675 0.19 ENSDART00000158064
ENSDART00000165746
ENSDART00000163917
ENSDART00000172038
ENSDART00000169048
ENSDART00000164775
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr19_-_26964348 0.19 ENSDART00000103955
zbtb12.2
zinc finger and BTB domain containing 12, tandem duplicate 2
chr9_+_33788389 0.19 ENSDART00000144623
kdm6a
lysine (K)-specific demethylase 6A
chr1_-_29061285 0.18 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gemin8
gem (nuclear organelle) associated protein 8
chr21_+_26071874 0.18 ENSDART00000003001
ENSDART00000146573
rpl23a
ribosomal protein L23a
chr24_+_32668675 0.17 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
si:ch211-282b22.1
chr6_-_10752937 0.17 ENSDART00000135093
ola1
Obg-like ATPase 1
chr3_+_24595922 0.17 ENSDART00000169405
si:dkey-68o6.5
si:dkey-68o6.5
chr9_+_12887491 0.17 ENSDART00000102386
si:ch211-167j6.4
si:ch211-167j6.4
chr25_+_30442389 0.17 ENSDART00000003346
pdcd2l
programmed cell death 2-like
chr11_+_24800156 0.17 ENSDART00000131976
adipor1a
adiponectin receptor 1a
chr24_-_42090635 0.17 ENSDART00000166413
ssr1
signal sequence receptor, alpha
chr9_+_27720428 0.16 ENSDART00000112415
lcmt2
leucine carboxyl methyltransferase 2
chr14_+_52408619 0.15 ENSDART00000163856
noa1
nitric oxide associated 1
chr8_-_40251126 0.15 ENSDART00000180435
kdm2ba
lysine (K)-specific demethylase 2Ba
chr2_+_50999477 0.15 ENSDART00000190111
eef1da
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr7_+_40148492 0.15 ENSDART00000110789
esyt2b
extended synaptotagmin-like protein 2b
chr9_-_29985390 0.14 ENSDART00000134157
il1rapl1a
interleukin 1 receptor accessory protein-like 1a
chr19_+_791538 0.14 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr7_+_49800849 0.12 ENSDART00000164838
ENSDART00000187888
PAMR1 (1 of many)
si:ch211-102l7.3
chr16_-_38629208 0.12 ENSDART00000126705
eif3ea
eukaryotic translation initiation factor 3, subunit E, a
chr22_+_5118361 0.12 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
mibp
muscle-specific beta 1 integrin binding protein
chr21_-_14832369 0.11 ENSDART00000144859
pus1
pseudouridylate synthase 1
chr11_-_21304452 0.11 ENSDART00000163008
RASSF5
si:dkey-85p17.3
chr23_+_25135858 0.11 ENSDART00000103986
fam3a
family with sequence similarity 3, member A
chr25_+_17405201 0.10 ENSDART00000164349
e2f4
E2F transcription factor 4
chr17_+_19499157 0.10 ENSDART00000077804
slc22a15
solute carrier family 22, member 15
chr2_+_19236969 0.10 ENSDART00000163875
ENSDART00000168644
cc2d1b
coiled-coil and C2 domain containing 1B
chr1_-_44025066 0.09 ENSDART00000148932
si:ch73-109d9.1
si:ch73-109d9.1
chr3_+_28939759 0.09 ENSDART00000141904
lgals1l1
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
chr10_+_39283985 0.09 ENSDART00000016464
dcps
decapping enzyme, scavenger
chr6_-_58975010 0.09 ENSDART00000144911
ENSDART00000144514
mars
methionyl-tRNA synthetase
chr17_-_29877336 0.08 ENSDART00000166976
esrrb
estrogen-related receptor beta
chr2_+_33796207 0.08 ENSDART00000124647
kiss1ra
KISS1 receptor a
chr7_-_39751540 0.08 ENSDART00000016803
grpel1
GrpE-like 1, mitochondrial
chr8_-_22739757 0.08 ENSDART00000182167
ENSDART00000171891
iqsec2a
IQ motif and Sec7 domain 2a
chr13_+_15702142 0.07 ENSDART00000135960
trmt61a
tRNA methyltransferase 61A
chr13_+_39277178 0.07 ENSDART00000113259
si:dkey-85a20.4
si:dkey-85a20.4
chr6_+_12462079 0.07 ENSDART00000192029
ENSDART00000065385
nr4a2b
nuclear receptor subfamily 4, group A, member 2b
chr11_+_42478184 0.07 ENSDART00000089963
zgc:110286
zgc:110286
chr5_-_26950374 0.07 ENSDART00000050542
htra4
HtrA serine peptidase 4
chr8_-_30979494 0.07 ENSDART00000138959
si:ch211-251j10.3
si:ch211-251j10.3
chr10_+_16036573 0.07 ENSDART00000188757
lmnb1
lamin B1
chr9_+_29985010 0.07 ENSDART00000020743
cmss1
cms1 ribosomal small subunit homolog (yeast)
chr25_+_17405458 0.07 ENSDART00000186711
e2f4
E2F transcription factor 4
chr15_-_12229874 0.06 ENSDART00000165159
dscaml1
Down syndrome cell adhesion molecule like 1
chr19_-_22346582 0.06 ENSDART00000045675
ENSDART00000169065
slc52a2
zgc:109744
solute carrier family 52 (riboflavin transporter), member 2
zgc:109744
chr19_-_24758109 0.06 ENSDART00000161016
si:dkey-154b15.1
si:dkey-154b15.1
chr24_+_10302955 0.06 ENSDART00000112455
ENSDART00000066794
ENSDART00000149432
otulina
otulina
OTU deubiquitinase with linear linkage specificity a
OTU deubiquitinase with linear linkage specificity a
chr10_+_16036246 0.06 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lmnb1
lamin B1
chr24_+_33392698 0.06 ENSDART00000122579
si:ch73-173p19.1
si:ch73-173p19.1
chr5_+_72194444 0.06 ENSDART00000165436
ddx54
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr12_+_28995942 0.06 ENSDART00000076334
valopb
vertebrate ancient long opsin b
chr2_+_19236677 0.06 ENSDART00000166292
cc2d1b
coiled-coil and C2 domain containing 1B
chr3_-_28120092 0.05 ENSDART00000151143
rbfox1
RNA binding fox-1 homolog 1
chr7_+_40148213 0.05 ENSDART00000173705
esyt2b
extended synaptotagmin-like protein 2b
chr5_+_3927989 0.05 ENSDART00000030125
znhit3
zinc finger, HIT-type containing 3
chr2_-_5199431 0.05 ENSDART00000063384
phb2a
prohibitin 2a
chr10_-_7913591 0.05 ENSDART00000139661
slc35e4
solute carrier family 35, member E4
chr14_+_5385855 0.05 ENSDART00000031508
lbx2
ladybird homeobox 2
chr8_-_49705058 0.04 ENSDART00000083760
frmd3
FERM domain containing 3
chr13_-_9061944 0.04 ENSDART00000164186
ENSDART00000102051
si:dkey-112g5.12
si:dkey-112g5.12
chr15_-_2632891 0.04 ENSDART00000081840
cldnj
claudin j
chr3_-_47038481 0.04 ENSDART00000193260
CR392045.1

chr21_+_3941758 0.04 ENSDART00000181345
setx
senataxin
chr25_+_10909850 0.04 ENSDART00000186021
CR339041.3

chr20_-_25645150 0.04 ENSDART00000063137
si:dkeyp-117h8.4
si:dkeyp-117h8.4
chr21_-_45382112 0.04 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr15_+_17621375 0.03 ENSDART00000158352
adamts15b
ADAM metallopeptidase with thrombospondin type 1 motif, 15b
chr7_+_20344032 0.03 ENSDART00000144948
ENSDART00000138786
ponzr1
plac8 onzin related protein 1
chr10_-_105100 0.03 ENSDART00000145716
ttc3
tetratricopeptide repeat domain 3
chr15_-_3940671 0.03 ENSDART00000189741
mindy4b
MINDY family member 4B
chr5_-_61609448 0.03 ENSDART00000133426
si:dkey-261j4.5
si:dkey-261j4.5
chr20_+_25445826 0.03 ENSDART00000012581
pfas
phosphoribosylformylglycinamidine synthase
chr13_-_18345854 0.03 ENSDART00000080107
si:dkey-228d14.5
si:dkey-228d14.5
chr10_-_15963903 0.03 ENSDART00000142357
si:dkey-3h23.3
si:dkey-3h23.3
chr25_+_29474982 0.02 ENSDART00000130410
il17rel
interleukin 17 receptor E-like
chr12_-_34716037 0.02 ENSDART00000152876
bahcc1b
BAH domain and coiled-coil containing 1b
chr2_+_39618951 0.02 ENSDART00000077108
zgc:136870
zgc:136870
chr8_+_46386601 0.02 ENSDART00000129661
ENSDART00000084081
ogg1
8-oxoguanine DNA glycosylase
chr14_+_16287968 0.02 ENSDART00000106593
prpf19
pre-mRNA processing factor 19
chr15_-_14552101 0.02 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr19_-_791016 0.02 ENSDART00000037515
msto1
misato 1, mitochondrial distribution and morphology regulator
chr13_+_25199849 0.02 ENSDART00000139209
ENSDART00000130876
ap3m1
adaptor-related protein complex 3, mu 1 subunit
chr4_+_18824959 0.02 ENSDART00000146141
ENSDART00000040424
slc26a3.1
solute carrier family 26 (anion exchanger), member 3
chr1_-_45042210 0.02 ENSDART00000073694
smu1b
SMU1, DNA replication regulator and spliceosomal factor b
chr15_-_14589677 0.02 ENSDART00000172195
coq8b
coenzyme Q8B
chr11_+_25296366 0.02 ENSDART00000065949
top1l
DNA topoisomerase I, like
chr3_+_57991074 0.01 ENSDART00000076077
myadml2
myeloid-associated differentiation marker-like 2
chr12_+_42436328 0.01 ENSDART00000167324
ebf3a
early B cell factor 3a
chr6_-_54078623 0.01 ENSDART00000154076
hyal1
hyaluronoglucosaminidase 1
chr7_+_20017211 0.01 ENSDART00000100808
bcl6b
B-cell CLL/lymphoma 6, member B
chr17_+_51627209 0.01 ENSDART00000056886
zgc:113142
zgc:113142
chr14_+_4796168 0.01 ENSDART00000041468
ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr20_+_25645459 0.01 ENSDART00000143555
ENSDART00000036350
aasdh
aminoadipate-semialdehyde dehydrogenase
chr1_-_54972170 0.01 ENSDART00000150548
ENSDART00000038330
khsrp
KH-type splicing regulatory protein
chr19_-_8940068 0.01 ENSDART00000043507
ciarta
circadian associated repressor of transcription a
chr11_+_45299447 0.01 ENSDART00000172999
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr19_-_32804535 0.00 ENSDART00000175613
ENSDART00000052098
nt5c1aa
5'-nucleotidase, cytosolic IAa
chr21_+_45510448 0.00 ENSDART00000160494
ENSDART00000167914
fnip1
folliculin interacting protein 1
chr10_+_29260096 0.00 ENSDART00000088973
sytl2a
synaptotagmin-like 2a
chr20_+_35998073 0.00 ENSDART00000140457
opn5
opsin 5

Network of associatons between targets according to the STRING database.

First level regulatory network of mycb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.2 0.6 GO:0001112 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.2 1.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 0.7 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 0.8 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.2 0.8 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.6 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.5 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.1 0.3 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.6 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 0.7 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.2 GO:1903358 regulation of Golgi organization(GO:1903358)
0.1 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 1.0 GO:0008354 germ cell migration(GO:0008354)
0.1 0.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.3 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.4 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.4 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:1904035 activation of MAPKKK activity(GO:0000185) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0030719 P granule organization(GO:0030719)
0.0 0.6 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.5 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.2 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.1 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.6 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 2.9 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034618 arginine binding(GO:0034618)
0.2 0.8 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.2 1.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 0.6 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.7 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.7 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 0.4 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.5 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.7 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.0 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)