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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for myf6

Z-value: 0.85

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Transcription factors associated with myf6

Gene Symbol Gene ID Gene Info
myf6
ENSDARG00000029830 myogenic factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myf6dr11_v1_chr4_+_21717793_217177930.532.4e-02Click!

Activity profile of myf6 motif

Sorted Z-values of myf6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_45319592 2.03 ENSDART00000189861
ccdc171
coiled-coil domain containing 171
chr17_-_5769196 1.78 ENSDART00000113885
si:dkey-100n19.2
si:dkey-100n19.2
chr11_-_6001845 1.67 ENSDART00000108628
ano8b
anoctamin 8b
chr13_+_27951688 1.45 ENSDART00000050303
b3gat2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr5_+_42381273 1.44 ENSDART00000142387
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr6_+_9241121 1.42 ENSDART00000064989
pimr70
Pim proto-oncogene, serine/threonine kinase, related 70
chr9_-_105135 1.33 ENSDART00000180126
FQ377903.3

chr7_+_44715224 1.32 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr5_-_29671586 1.26 ENSDART00000098336
spaca9
sperm acrosome associated 9
chr10_-_625441 1.26 ENSDART00000171171
rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr6_-_9459440 1.23 ENSDART00000064991
pimr71
Pim proto-oncogene, serine/threonine kinase, related 71
chr6_-_39313027 1.20 ENSDART00000012644
krt4
keratin 4
chr19_-_5332784 1.20 ENSDART00000010373
krt1-19d
keratin, type 1, gene 19d
chr13_-_7767044 1.19 ENSDART00000159453
h2afy2
H2A histone family, member Y2
chr21_+_198269 1.15 ENSDART00000193485
ENSDART00000163696
gsdf
gonadal somatic cell derived factor
chr17_-_39786222 1.11 ENSDART00000154515
pimr62
Pim proto-oncogene, serine/threonine kinase, related 62
chr5_-_71705191 1.10 ENSDART00000187767
ak1
adenylate kinase 1
chr22_-_3344613 1.08 ENSDART00000165600
tbxa2r
thromboxane A2 receptor
chr21_-_18972206 1.07 ENSDART00000146743
pimr72
Pim proto-oncogene, serine/threonine kinase, related 72
chr13_-_7766758 1.04 ENSDART00000171831
h2afy2
H2A histone family, member Y2
chr1_-_625875 1.02 ENSDART00000167331
appa
amyloid beta (A4) precursor protein a
chr5_+_29671681 1.02 ENSDART00000043096
ak8
adenylate kinase 8
chr22_-_5099824 1.02 ENSDART00000122341
ENSDART00000161345
zfr2
zinc finger RNA binding protein 2
chr25_+_1035656 1.01 ENSDART00000179843
ENSDART00000168637
si:ch211-284k5.2
si:ch211-284k5.2
chr23_-_45318760 1.01 ENSDART00000166883
ccdc171
coiled-coil domain containing 171
chr8_-_50259448 0.98 ENSDART00000146056
nkx3-1
NK3 homeobox 1
chr10_-_690072 0.95 ENSDART00000164871
ENSDART00000142833
glis3
GLIS family zinc finger 3
chr14_-_36862745 0.95 ENSDART00000109293
rnf130
ring finger protein 130
chr1_+_57311901 0.94 ENSDART00000149397
mycbpap
mycbp associated protein
chr5_-_36948586 0.93 ENSDART00000193606
h3f3c
H3 histone, family 3C
chr5_+_19867794 0.90 ENSDART00000051614
tchp
trichoplein, keratin filament binding
chr9_-_48407408 0.89 ENSDART00000058248
zgc:172182
zgc:172182
chr19_+_31904836 0.89 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tpd52
tumor protein D52
chr25_+_245018 0.88 ENSDART00000155344
zgc:92481
zgc:92481
chr5_+_42467867 0.87 ENSDART00000172028
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr2_-_7696287 0.86 ENSDART00000190769
CABZ01055306.1

chr5_-_19400166 0.85 ENSDART00000008994
foxn4
forkhead box N4
chr23_-_12423778 0.83 ENSDART00000124091
wfdc2
WAP four-disulfide core domain 2
chr21_-_3452683 0.83 ENSDART00000009740
smad7
SMAD family member 7
chr3_-_22829710 0.82 ENSDART00000055659
cyb561
cytochrome b561
chr20_-_9199721 0.82 ENSDART00000064140
ylpm1
YLP motif containing 1
chr4_+_69619 0.81 ENSDART00000164425
mansc1
MANSC domain containing 1
chr17_-_7861219 0.79 ENSDART00000148604
syne1b
spectrin repeat containing, nuclear envelope 1b
chr4_+_90048 0.78 ENSDART00000166440
lrp6
low density lipoprotein receptor-related protein 6
chr7_-_20756013 0.78 ENSDART00000185259
chd3
chromodomain helicase DNA binding protein 3
chr9_-_68934 0.77 ENSDART00000054594
ENSDART00000009389
il10rb
interleukin 10 receptor, beta
chr25_-_13188214 0.76 ENSDART00000187298
si:ch211-147m6.1
si:ch211-147m6.1
chr5_+_62723233 0.76 ENSDART00000183718
nanos2
nanos homolog 2
chr6_+_9893554 0.76 ENSDART00000064979
pimr74
Pim proto-oncogene, serine/threonine kinase, related 74
chr12_+_18533198 0.75 ENSDART00000189729
meiob
meiosis specific with OB domains
chr1_-_52498146 0.74 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr2_+_27491066 0.74 ENSDART00000078305
zswim5
zinc finger, SWIM-type containing 5
chr7_+_1467863 0.74 ENSDART00000173433
emc4
ER membrane protein complex subunit 4
chr25_-_4482449 0.73 ENSDART00000056278
ENSDART00000149425
slc25a22a
solute carrier family 25 member 22a
chr8_+_54188978 0.72 ENSDART00000175913
FO904970.1

chr12_-_145076 0.72 ENSDART00000160926
dnah9
dynein, axonemal, heavy chain 9
chr12_-_47793857 0.71 ENSDART00000161294
dydc2
DPY30 domain containing 2
chr13_-_37619159 0.71 ENSDART00000186348
zgc:152791
zgc:152791
chr22_+_35472653 0.70 ENSDART00000076424
ENSDART00000187204
tctex1d2
Tctex1 domain containing 2
chr5_+_42402536 0.69 ENSDART00000186754
BX548073.11

chr4_+_61171310 0.69 ENSDART00000141738
si:dkey-9p20.18
si:dkey-9p20.18
chr13_-_438705 0.68 ENSDART00000082142
CU570800.1

chr22_-_38607504 0.66 ENSDART00000164609
si:ch211-126j24.1
si:ch211-126j24.1
chr16_+_52512025 0.66 ENSDART00000056095
fabp10a
fatty acid binding protein 10a, liver basic
chr3_+_26145013 0.65 ENSDART00000162546
ENSDART00000129561
atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr11_-_30636163 0.65 ENSDART00000140516
zgc:153665
zgc:153665
chr20_+_52774730 0.63 ENSDART00000014606
phactr1
phosphatase and actin regulator 1
chr12_-_11570 0.63 ENSDART00000186179
shisa6
shisa family member 6
chr18_+_41250938 0.63 ENSDART00000087566
trip12
thyroid hormone receptor interactor 12
chr7_-_59256806 0.63 ENSDART00000167955
m1ap
meiosis 1 associated protein
chr8_+_26522013 0.62 ENSDART00000046863
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr10_-_44027391 0.62 ENSDART00000145404
crybb1
crystallin, beta B1
chr19_+_31404686 0.60 ENSDART00000078459
pip4p2
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2
chr18_-_44285539 0.60 ENSDART00000137222
pimr179
Pim proto-oncogene, serine/threonine kinase, related 179
chr25_+_37480285 0.60 ENSDART00000166187
CABZ01095001.1

chr4_-_64709908 0.60 ENSDART00000161032
si:dkey-9i5.2
si:dkey-9i5.2
chr22_+_24715282 0.60 ENSDART00000088027
ENSDART00000189054
ENSDART00000140430
ssx2ipb
synovial sarcoma, X breakpoint 2 interacting protein b
chr6_-_9922266 0.59 ENSDART00000151549
pimr73
Pim proto-oncogene, serine/threonine kinase, related 73
chr13_-_28674422 0.57 ENSDART00000122754
ENSDART00000057574
nt5c2a
5'-nucleotidase, cytosolic IIa
chr10_+_35265083 0.57 ENSDART00000048831
tmem120a
transmembrane protein 120A
chr1_-_59407322 0.57 ENSDART00000161661
si:ch211-188p14.5
si:ch211-188p14.5
chr2_-_7696503 0.56 ENSDART00000169709
CABZ01055306.1

chr8_+_53928472 0.56 ENSDART00000063242
MMP23B
matrix metallopeptidase 23B
chr1_-_52497834 0.55 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr14_+_39255437 0.54 ENSDART00000147443
diaph2
diaphanous-related formin 2
chr10_+_41986685 0.54 ENSDART00000086165
ENSDART00000171983
setd1ba
SET domain containing 1B, a
chr13_-_37615029 0.54 ENSDART00000111199
si:dkey-188i13.6
si:dkey-188i13.6
chr4_-_38033800 0.53 ENSDART00000159662
si:dkeyp-82b4.4
si:dkeyp-82b4.4
chr13_-_37180815 0.53 ENSDART00000139907
si:dkeyp-77c8.1
si:dkeyp-77c8.1
chr20_+_34029820 0.53 ENSDART00000143901
ENSDART00000134305
prg4b
proteoglycan 4b
chr19_-_42391383 0.53 ENSDART00000110075
ENSDART00000087002
plekho1a
pleckstrin homology domain containing, family O member 1a
chr1_-_52128425 0.53 ENSDART00000149939
rad23aa
RAD23 homolog A, nucleotide excision repair protein a
chr17_+_41992054 0.53 ENSDART00000182878
ENSDART00000111537
kiz
kizuna centrosomal protein
chr10_+_439692 0.52 ENSDART00000147740
zdhhc8a
zinc finger, DHHC-type containing 8a
chr3_-_3496738 0.52 ENSDART00000186849
CABZ01040998.1

chr21_+_18353703 0.52 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
si:ch73-287m6.1
chr21_-_30545121 0.52 ENSDART00000019199
rab39ba
RAB39B, member RAS oncogene family a
chr10_+_16592851 0.51 ENSDART00000187508
ENSDART00000101142
chsy3
chondroitin sulfate synthase 3
chr2_-_57891504 0.51 ENSDART00000139948
zgc:92789
zgc:92789
chr23_+_4288964 0.51 ENSDART00000138408
l3mbtl1
l(3)mbt-like 1 (Drosophila)
chr11_-_8208464 0.51 ENSDART00000161283
pimr203
Pim proto-oncogene, serine/threonine kinase, related 203
chr21_+_45496442 0.51 ENSDART00000164880
si:dkey-223p19.1
si:dkey-223p19.1
chr5_-_72136548 0.51 ENSDART00000007827
spra
sepiapterin reductase a
chr16_-_54405976 0.50 ENSDART00000055395
osr2
odd-skipped related transciption factor 2
chr18_+_5549672 0.50 ENSDART00000184970
nnt2
nicotinamide nucleotide transhydrogenase 2
chr1_-_18446161 0.50 ENSDART00000089442
klhl5
kelch-like family member 5
chr2_+_13462305 0.50 ENSDART00000149309
ENSDART00000080900
cfap57
cilia and flagella associated protein 57
chr13_+_30903816 0.50 ENSDART00000191727
ercc6
excision repair cross-complementation group 6
chr21_+_45366229 0.49 ENSDART00000029946
ube2b
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr2_-_2937225 0.49 ENSDART00000168132
si:ch1073-82l19.1
si:ch1073-82l19.1
chr14_-_36863432 0.49 ENSDART00000158052
rnf130
ring finger protein 130
chr12_+_47945664 0.48 ENSDART00000189824
ENSDART00000055743
ENSDART00000188936
CABZ01074994.1

chr13_-_6218248 0.48 ENSDART00000159052
si:zfos-1056e6.1
si:zfos-1056e6.1
chr23_-_46201008 0.48 ENSDART00000160110
tgm1l4
transglutaminase 1 like 4
chr8_-_29719393 0.48 ENSDART00000077635
si:ch211-103n10.5
si:ch211-103n10.5
chr23_-_42752550 0.48 ENSDART00000187059
si:ch73-217n20.1
si:ch73-217n20.1
chr1_+_52398205 0.48 ENSDART00000143225
si:ch211-217k17.9
si:ch211-217k17.9
chr4_+_10017049 0.48 ENSDART00000144175
ccdc136b
coiled-coil domain containing 136b
chr23_-_19558556 0.47 ENSDART00000134012
dnah12
dynein, axonemal, heavy chain 12
chr18_+_37259800 0.47 ENSDART00000078053
ENSDART00000132577
tbcb
tubulin folding cofactor B
chr12_+_18532866 0.47 ENSDART00000152126
ENSDART00000152443
ENSDART00000089589
meiob
meiosis specific with OB domains
chr12_+_49135755 0.47 ENSDART00000153460
si:zfos-911d5.4
si:zfos-911d5.4
chr25_-_518656 0.47 ENSDART00000156421
myo9ab
myosin IXAb
chr23_+_44644911 0.46 ENSDART00000140799
zgc:85858
zgc:85858
chr8_-_6877390 0.46 ENSDART00000170883
ENSDART00000005321
neflb
neurofilament, light polypeptide b
chr24_+_26997798 0.46 ENSDART00000089506
larp4b
La ribonucleoprotein domain family, member 4B
chr12_+_18782821 0.45 ENSDART00000152918
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr2_-_26563978 0.45 ENSDART00000150016
glis1a
GLIS family zinc finger 1a
chr4_-_9764767 0.45 ENSDART00000164328
ENSDART00000147699
mical3b
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr14_+_31657412 0.45 ENSDART00000105767
fhl1a
four and a half LIM domains 1a
chr22_+_20720808 0.45 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr9_+_22657221 0.45 ENSDART00000101765
si:dkey-189g17.2
si:dkey-189g17.2
chr19_+_63567 0.45 ENSDART00000165657
ENSDART00000165183
zhx2b
zinc fingers and homeoboxes 2b
chr24_-_35707552 0.45 ENSDART00000165199
mapre2
microtubule-associated protein, RP/EB family, member 2
chr2_-_56431298 0.45 ENSDART00000182544
ctxn1
cortexin 1
chr8_+_52788997 0.44 ENSDART00000169198
adgrd2
adhesion G protein-coupled receptor D2
chr1_-_36151377 0.44 ENSDART00000037516
znf827
zinc finger protein 827
chr9_-_296169 0.44 ENSDART00000165228
kif5aa
kinesin family member 5A, a
chr25_+_37209619 0.44 ENSDART00000112192
si:dkey-234i14.3
si:dkey-234i14.3
chr20_+_48100261 0.44 ENSDART00000158604
xkr5a
XK related 5a
chr9_+_41024973 0.44 ENSDART00000014660
ENSDART00000144467
ormdl1
ORMDL sphingolipid biosynthesis regulator 1
chr8_+_53344726 0.44 ENSDART00000184395
ENSDART00000170212
CU914536.1

chr13_+_48482256 0.44 ENSDART00000053332
FOXN2 (1 of many)
forkhead box N2
chr19_+_551963 0.43 ENSDART00000110495
akap9
A kinase (PRKA) anchor protein 9
chr17_+_32500387 0.43 ENSDART00000018423
ywhaqb
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr5_-_67895656 0.43 ENSDART00000158917
abhd10a
abhydrolase domain containing 10a
chr4_-_8093753 0.43 ENSDART00000133434
wnk1b
WNK lysine deficient protein kinase 1b
chr13_-_19799824 0.43 ENSDART00000058032
fam204a
family with sequence similarity 204, member A
chr10_-_5020378 0.42 ENSDART00000191857
hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr20_-_29787192 0.42 ENSDART00000125348
ENSDART00000048759
id2b
inhibitor of DNA binding 2b
chr5_+_2815021 0.42 ENSDART00000020472
hpda
4-hydroxyphenylpyruvate dioxygenase a
chr25_-_3549321 0.42 ENSDART00000181214
ENSDART00000160600
hdhd5
haloacid dehalogenase like hydrolase domain containing 5
chr5_+_43530388 0.42 ENSDART00000190254
ENSDART00000097618
ENSDART00000133006
si:dkey-40c11.2
si:dkey-40c11.2
chr5_-_46273938 0.42 ENSDART00000080033
si:ch211-130m23.3
si:ch211-130m23.3
chr17_+_46739693 0.42 ENSDART00000097810
pimr22
Pim proto-oncogene, serine/threonine kinase, related 22
chr23_+_23658474 0.42 ENSDART00000162838
agrn
agrin
chr14_+_15191176 0.42 ENSDART00000183447
ENSDART00000193093
ENSDART00000169309
si:dkey-203a12.2
si:dkey-203a12.2
chr23_-_19558263 0.41 ENSDART00000084477
ENSDART00000179748
ENSDART00000193127
dnah12
dynein, axonemal, heavy chain 12
chr7_-_27037990 0.41 ENSDART00000173561
nucb2a
nucleobindin 2a
chr14_+_41345175 0.41 ENSDART00000086104
nox1
NADPH oxidase 1
chr7_+_17816470 0.41 ENSDART00000173807
eml3
echinoderm microtubule associated protein like 3
chr21_-_32467799 0.41 ENSDART00000007675
ENSDART00000133099
zgc:123105
zgc:123105
chr25_-_4525081 0.41 ENSDART00000184347
pidd1
p53-induced death domain protein 1
chr12_-_17810543 0.41 ENSDART00000090484
tecpr1a
tectonin beta-propeller repeat containing 1a
chr2_-_58902477 0.41 ENSDART00000061638
ENSDART00000172822
mau2
MAU2 sister chromatid cohesion factor
chr14_-_33454595 0.40 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
tmem255a
transmembrane protein 255A
chr2_-_183992 0.40 ENSDART00000126704
ENSDART00000191283
ENSDART00000034783
zgc:113518
zgc:113518
chr10_+_10351685 0.40 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr19_-_46957968 0.40 ENSDART00000043713
angpt1
angiopoietin 1
chr1_-_46505310 0.40 ENSDART00000178072
si:busm1-105l16.2
si:busm1-105l16.2
chr19_+_48410195 0.40 ENSDART00000166877
si:ch1073-376c22.1
si:ch1073-376c22.1
chr7_-_73848458 0.40 ENSDART00000041385
zgc:163061
zgc:163061
chr7_+_34506937 0.39 ENSDART00000111303
rfx7a
regulatory factor X7a
chr4_+_12358822 0.39 ENSDART00000172557
ENSDART00000150627
pimr168
Pim proto-oncogene, serine/threonine kinase, related 168
chr3_+_1211242 0.39 ENSDART00000171287
ENSDART00000165769
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr14_-_46310549 0.39 ENSDART00000123832
crybb1l1
crystallin, beta B1, like 1
chr17_+_23255365 0.39 ENSDART00000180277
AL935174.5

chr20_+_591505 0.39 ENSDART00000046438
kcnk2b
potassium channel, subfamily K, member 2b
chr13_+_681628 0.39 ENSDART00000016604
abcc2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr2_-_20599315 0.39 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr14_+_45732081 0.38 ENSDART00000110103
ccdc88b
coiled-coil domain containing 88B
chr10_+_17592273 0.38 ENSDART00000141221
KCNN2
si:dkey-76p7.5
chr15_-_19771981 0.38 ENSDART00000175502
ENSDART00000159475
picalmb
phosphatidylinositol binding clathrin assembly protein b
chr6_+_11989537 0.38 ENSDART00000190817
baz2ba
bromodomain adjacent to zinc finger domain, 2Ba
chr7_+_19903924 0.38 ENSDART00000159112
si:ch211-285j22.3
si:ch211-285j22.3
chr25_+_3549401 0.38 ENSDART00000166312
ccdc77
coiled-coil domain containing 77
chr17_-_6600899 0.38 ENSDART00000154074
ENSDART00000180912
ANKRD66
si:ch211-189e2.2
chr3_-_56924654 0.38 ENSDART00000157038
hid1a
HID1 domain containing a
chr10_+_25355308 0.38 ENSDART00000100415
map3k7cl
map3k7 C-terminal like
chr18_+_37272568 0.37 ENSDART00000132749
tmem123
transmembrane protein 123
chr6_+_53429228 0.37 ENSDART00000165067
abhd14b
abhydrolase domain containing 14B
chr21_-_43040780 0.37 ENSDART00000187037
jakmip2
janus kinase and microtubule interacting protein 2
chr23_+_20795781 0.37 ENSDART00000128577
ttc34
tetratricopeptide repeat domain 34
chr1_-_45920632 0.37 ENSDART00000140890
pnpla6
patatin-like phospholipase domain containing 6
chr24_-_21674950 0.37 ENSDART00000123216
ENSDART00000046211
lnx2a
ligand of numb-protein X 2a
chr18_-_26977940 0.37 ENSDART00000147823
rcn2
reticulocalbin 2
chr2_+_16160906 0.36 ENSDART00000135783
selenoj
selenoprotein J
chr23_-_306796 0.36 ENSDART00000143125
anks1aa
ankyrin repeat and sterile alpha motif domain containing 1Aa
chr13_+_233482 0.36 ENSDART00000102511
cfap36
cilia and flagella associated protein 36
chr15_+_3284684 0.36 ENSDART00000179778
foxo1a
forkhead box O1 a

Network of associatons between targets according to the STRING database.

First level regulatory network of myf6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.2 1.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2 1.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 0.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.4 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.4 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.6 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.5 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.4 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.3 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.1 0.3 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.4 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.4 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.7 GO:0006953 acute-phase response(GO:0006953)
0.1 0.7 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 2.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.4 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.5 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.4 GO:0015871 choline transport(GO:0015871)
0.1 1.1 GO:0045777 positive regulation of blood pressure(GO:0045777)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.7 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 0.5 GO:0061511 centriole elongation(GO:0061511)
0.1 0.8 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 2.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.2 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.1 0.7 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0043584 nose development(GO:0043584)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.1 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.3 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:0060879 peripheral nervous system myelin formation(GO:0032290) semicircular canal fusion(GO:0060879)
0.1 0.3 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.3 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.1 0.6 GO:0045444 fat cell differentiation(GO:0045444)
0.1 1.1 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.1 0.2 GO:0003413 plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.9 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.4 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.2 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.2 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.5 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 1.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0033238 regulation of cellular amino acid metabolic process(GO:0006521) regulation of cellular amine metabolic process(GO:0033238)
0.0 0.6 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.3 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.2 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.0 0.9 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.2 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 1.0 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.1 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.2 GO:0055014 atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.2 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.3 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.6 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.5 GO:1902307 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.3 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.5 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 11.0 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.1 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.1 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.2 GO:0055016 hypochord development(GO:0055016)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.1 GO:0048940 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.4 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0014009 glial cell proliferation(GO:0014009) regulation of glial cell proliferation(GO:0060251)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 1.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.3 GO:0003139 secondary heart field specification(GO:0003139)
0.0 0.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.3 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 0.4 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0035912 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.2 GO:0030431 sleep(GO:0030431)
0.0 0.1 GO:0016037 light absorption(GO:0016037)
0.0 0.0 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.5 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.2 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 1.3 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)
0.0 0.2 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.9 GO:0003341 cilium movement(GO:0003341)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0001964 startle response(GO:0001964)
0.0 0.3 GO:0021551 central nervous system morphogenesis(GO:0021551)
0.0 0.1 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.9 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.5 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.1 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.4 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.1 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.8 GO:0022900 electron transport chain(GO:0022900)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.0 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.3 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.1 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0008207 C21-steroid hormone metabolic process(GO:0008207)
0.0 0.0 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0014020 neural tube closure(GO:0001843) primary neural tube formation(GO:0014020) tube closure(GO:0060606)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031673 H zone(GO:0031673)
0.2 2.0 GO:0045095 keratin filament(GO:0045095)
0.2 1.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.9 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0005883 neurofilament(GO:0005883)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 1.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 1.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:1990071 TRAPPII protein complex(GO:1990071)
0.1 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.8 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0043198 ciliary rootlet(GO:0035253) dendritic shaft(GO:0043198)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.8 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 1.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 1.3 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 1.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 0.8 GO:0004904 interferon receptor activity(GO:0004904)
0.2 1.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.2 1.1 GO:0004960 thromboxane receptor activity(GO:0004960)
0.1 0.4 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.5 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0031704 apelin receptor binding(GO:0031704)
0.1 1.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.7 GO:0032052 bile acid binding(GO:0032052)
0.1 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.7 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.1 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.3 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.3 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.7 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.3 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.4 GO:0008126 acetylesterase activity(GO:0008126)
0.1 0.5 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.2 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.9 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.2 GO:0042974 estrogen receptor binding(GO:0030331) retinoic acid receptor binding(GO:0042974)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.3 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.0 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 1.3 GO:0008201 heparin binding(GO:0008201)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 9.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 1.8 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol